CN113892980A - Recovery unit of tumour tissue in intracranial high-grade glioma art - Google Patents

Recovery unit of tumour tissue in intracranial high-grade glioma art Download PDF

Info

Publication number
CN113892980A
CN113892980A CN202111317854.9A CN202111317854A CN113892980A CN 113892980 A CN113892980 A CN 113892980A CN 202111317854 A CN202111317854 A CN 202111317854A CN 113892980 A CN113892980 A CN 113892980A
Authority
CN
China
Prior art keywords
storage bottle
liquid storage
pipe
centrifugal
sample inlet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202111317854.9A
Other languages
Chinese (zh)
Inventor
张鹏
吴翠莹
李运军
戴以武
徐如祥
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN202111317854.9A priority Critical patent/CN113892980A/en
Publication of CN113892980A publication Critical patent/CN113892980A/en
Pending legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/0233Pointed or sharp biopsy instruments
    • A61B10/0283Pointed or sharp biopsy instruments with vacuum aspiration, e.g. caused by retractable plunger or by connected syringe

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medical Informatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • External Artificial Organs (AREA)
  • Centrifugal Separators (AREA)

Abstract

The application discloses recovery unit of tumour tissue in intracranial high-level glioma art includes: the top end of the liquid storage bottle is closed and is connected with a suction apparatus connecting pipe and a cleaning solution conveying pipe, and the cleaning solution conveying pipe is connected with the cleaning solution storage bottle and is used for conveying the cleaning solution to the liquid storage bottle; the discharge end of the negative pressure aspirator is communicated with the aspirator connecting pipe; the centrifugal collecting assembly comprises a centrifugal device, a centrifugal sleeve arranged inside the centrifugal device and a sample inlet pipe connected to the bottom end of the liquid storage bottle, wherein the centrifugal sleeve is communicated with the discharge end of the sample inlet pipe. The utility model provides a recovery unit simple structure can collect a large amount of tumor tissue and not increase patient's health burden, and the tumor tissue of retrieving can be used to the process of diagnosing in patient's later stage, can avoid the gene detection that causes because of tumor tissue draws materials not enough and leak or cause the condition that can't effectively activate external immune cell because of patient's tumor tissue is not enough in the biological treatment process of later stage.

Description

Recovery unit of tumour tissue in intracranial high-grade glioma art
Technical Field
The invention relates to the technical field of medical auxiliary instruments, in particular to a device for recovering tumor tissues in intracranial high-grade glioma operation.
Background
In recent years, with the rapid development of molecular biology, genetic biology and other disciplines, immunotherapy and gene therapy of tumors have become new tumor treatment modalities. Whether biological immunotherapy or gene therapy, tumor tissues at corresponding parts are required to be obtained for in vitro culture or gene detection. The pathological tissues are obtained to be used as the core work for making pathological diagnosis in the medical treatment process, and for most diseases, the difficulty is not high as long as invasive or non-invasive professional means are adopted; and for diseases with small focus, difficult material taking or easy secondary damage to patients in the material taking process, such as high-grade glioma and cord cell tumor, because the blood supply of the tumor is abundant, a large amount of tissues are reserved at one time, the blood output is easily increased, and meanwhile, the brain tissue is excessively pulled, so that the secondary damage is easily caused. Many meaningful pathological tissues are directly sucked away by a suction apparatus in the operation process, the quantity of the taken tissues ensures that the pathological diagnosis is still possible, but the gene detection or the biological immunotherapy is very reluctant. Therefore, in clinical work, how to effectively recover pathological tissues is a difficult problem.
Disclosure of Invention
In view of the above defects or shortcomings in the prior art, it is desirable to provide a device for recovering tumor tissue in intracranial high-grade glioma operation, which has a simple structure, can effectively recover a large amount of tumor tissue without increasing the burden of the body of a patient, and the recovered tumor tissue can be used in the later diagnosis and treatment process of the patient.
In a first aspect, the present application provides a device for recovering tumor tissue in intracranial high-grade glioma surgery, comprising:
the top end of the liquid storage bottle is closed and is connected with a suction apparatus connecting pipe and a cleaning solution conveying pipe, and the cleaning solution conveying pipe is connected with the cleaning solution storage bottle and is used for conveying the cleaning solution to the liquid storage bottle;
the discharge end of the negative pressure aspirator is communicated with the aspirator connecting pipe;
the centrifugal collecting assembly comprises a centrifugal device, a centrifugal sleeve arranged inside the centrifugal device and a sample inlet pipe connected to the bottom end of the liquid storage bottle, wherein the centrifugal sleeve is communicated with the discharge end of the sample inlet pipe.
As an optional scheme, the device also comprises a red blood cell lysate storage bottle, and a lysate conveying pipe is arranged between the red blood cell lysate storage bottle and the liquid storage bottle and is used for conveying the red blood cell lysate to the liquid storage bottle.
As an optional scheme, the device also comprises a peristaltic pump, and the peristaltic pump is connected with the washing liquid conveying pipe and the lysis liquid conveying pipe.
As an alternative, the negative pressure aspirator comprises:
the suction apparatus head is connected with the suction apparatus connecting pipe;
the first negative pressure pump is connected with an air exhaust pipe which is communicated with the liquid storage bottle and is used for forming negative pressure inside the liquid storage bottle.
As an optional scheme, a switch part is arranged at the joint of the sample introduction end of the sample introduction tube and the bottom end of the liquid storage bottle, and the switch part is used for adjusting the communication state of the bottom end of the liquid storage bottle and the sample introduction end of the sample introduction tube.
Optionally, the switch is used for adjusting the communication state between the bottom end of the liquid storage bottle and the sample inlet end of the sample inlet tube under the action of pressure.
As an optional scheme, one end of the movable baffle is fixed on the side wall of the bottom end of the liquid storage bottle;
the compression air bag is connected with the other end of the movable baffle through a connecting wire and is used for automatically adjusting the tightness state of the connecting wire through the internal pressure change so as to adjust the communication state of the bottom end of the liquid storage bottle and the sample inlet end of the sample inlet pipe.
As an optional scheme, the compression air bag is respectively connected with a first pipeline and a second pipeline, the first pipeline is connected with a booster pump, and the second pipeline is connected with a second negative pressure pump.
As an optional scheme, the centrifugal sleeve comprises an inner pipe and an outer pipe sleeved outside the inner pipe, wherein a defoaming net and a sterile filter felt are sequentially arranged on the side wall of the inner pipe and used for filtering and collecting tumor tissues, and the outer pipe is used for collecting waste liquid.
Optionally, the inside of the reservoir is further coated with heparin.
The utility model provides a recovery unit of tumour tissue in intracranial high-level glioma art through siphoning away tumour tissue with the vacuum aspiration ware at the operation in-process, then collects centrifugal sleeve pipe with tumour tissue is unified, then through the centrifugation means, gets rid of the blood component of adhesion, collects pathological tissue. The utility model provides a recovery unit simple structure, convenient to use, it is big that the direct tissue volume of collecting through the negative pressure aspirator in the operation process need not additionally excise the tissue again from the patient health, consequently does not increase patient health burden to the tumour tissue of retrieving can be used to the process of diagnosing in patient later stage.
Drawings
Other features, objects and advantages of the present application will become more apparent upon reading of the following detailed description of non-limiting embodiments thereof, made with reference to the accompanying drawings in which:
FIG. 1 is a schematic structural diagram of a device for recovering tumor tissue in intracranial high-grade glioma surgery according to an embodiment of the present invention;
in the figure, the position of the upper end of the main shaft,
1. the device comprises a liquid storage bottle, 11, an aspirator connecting pipe, 12, a washing liquid conveying pipe, 21, an aspirator connector, 22, a first negative pressure pump, 23, an air suction pipe, 31, a centrifugal device, 32, a centrifugal sleeve, 321, an inner defoaming net pipe, 322, a sterile filter felt, 33, a sample inlet pipe, 4, an erythrocyte lysate storage bottle, 41, a lysate conveying pipe, 5, a peristaltic pump, 61, a movable baffle, 62, a compression air bag, 63, a first pipeline, 64, a second pipeline, 65, a booster pump, 66, a second negative pressure pump and 7, a washing liquid storage bottle.
Detailed Description
The present application will be described in further detail with reference to the following drawings and examples. It is to be understood that the specific embodiments described herein are merely illustrative of the relevant invention and not restrictive of the invention. It should be noted that, for convenience of description, only the portions related to the present invention are shown in the drawings.
It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict. The present application will be described in detail below with reference to the embodiments with reference to the attached drawings.
The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the application. As used in this application and the appended claims, the singular forms "a", "an", and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise. It should also be understood that the term "and/or" as used herein refers to and encompasses any and all possible combinations of one or more of the associated listed items.
In a first aspect, an embodiment of the present application provides a device for recovering tumor tissue in intracranial high-grade glioma surgery, as shown in fig. 1, comprising:
the top end of the liquid storage bottle 1 is closed and is connected with a suction apparatus connecting pipe 11 and a cleaning solution conveying pipe 12, and the cleaning solution conveying pipe 12 is connected with a cleaning solution storage bottle 12 and is used for conveying cleaning solution to the liquid storage bottle 1;
the discharge end of the negative pressure aspirator is communicated with the aspirator connecting pipe 11;
the centrifugal collecting assembly comprises a centrifugal device 31, a centrifugal sleeve 32 arranged inside the centrifugal device 31 and a sample inlet pipe 33 connected to the bottom end of the liquid storage bottle 1, wherein the centrifugal sleeve 32 is communicated with the discharge end of the sample inlet pipe 33.
The liquid storage bottle 1 is used for containing erythrocyte lysate, washing liquid and tumor tissues sucked and led out by a negative pressure suction apparatus; wherein the erythrocyte lysate is used for lysing blood adhered to the surface of the tumor tissue; the washing liquid is used for washing tumor tissues, including washing cracked blood components, so that the tumor tissues can smoothly flow into the centrifugal collection component, particularly the centrifugal sleeve 32, through the sampling tube 33, and loss caused by the fact that the tumor tissues are sticky and stuck on the inner wall of the liquid storage bottle is reduced.
The negative pressure aspirator is mainly used for pumping the interior of the liquid storage bottle 1 into negative pressure, so that tumor tissues enter the liquid storage bottle 1 through the aspirator connecting pipe 11, the operation is convenient, the burden on the body of a patient is avoided, meanwhile, the tumor tissues are directly collected into the liquid storage bottle 1, the tumor tissues are prevented from being exposed and polluted outside, and the recovered pathological tissues are ensured to reach the sterile level of in vitro culture.
The centrifugal collecting component is mainly used for collecting tumor tissues; wherein, centrifugal device 31 includes parts such as including centrifuge main shaft, bearing and centrifugal rotary drum, and centrifugal sleeve 32 is installed inside centrifugal device, through centrifugal force, gets rid of the blood component on the tumour tissue, collects tumour tissue inside centrifugal sleeve 32 to collect the waste liquid that the centrifugation produced.
The recovery unit of this application embodiment has solved current tumour tissue and has collected the volume less, can't effectively collect the problem of tumour tissue. The embodiment of the application sucks away tumor tissues by using the negative pressure suction apparatus in the operation process, then collects the tumor tissues to the centrifugal sleeve uniformly, removes adhered blood components by a centrifugal means, and collects pathological tissues. The utility model provides a recovery unit simple structure, convenient to use, it is big that the direct tissue volume of collecting through the negative pressure aspirator in the operation process need not additionally excise the tissue again from the patient health, consequently does not increase patient health burden to the tumour tissue of retrieving can be used to the process of diagnosing in patient later stage.
As a realizable mode, the red blood cell lysate storage bottle 4 is also included, and a lysate conveying pipe 41 is arranged between the red blood cell lysate storage bottle 4 and the liquid storage bottle 1 and used for conveying the red blood cell lysate to the liquid storage bottle 1.
In the embodiment, the red blood cell lysate storage bottle 4 is filled with the red blood cell lysate, the red blood cell lysate enters the lysate conveying pipe 41 to be conveyed into the storage bottle, and the red blood cell lysate can timely lyse red blood cells in a sample mixture, so that the red blood cells can be conveniently filtered and separated in the centrifugal process, and the interference on the sample is reduced; the lysate transport tube 41 is connected to the top end of the liquid storage bottle 1.
As a practical way, a peristaltic pump 5 is also included, the peristaltic pump 5 being connected to the washing solution duct 12 and the lysis solution duct 41. Wherein, the peristaltic pump 5 provides power, and the cleaning solution conveying pipe 12 and the lysate conveying pipe 41 are connected to the peristaltic pump 5 together, which is beneficial to conveying the cleaning solution and the erythrocyte lysate to the liquid storage bottle 1.
As a preferred embodiment, the negative pressure aspirator includes:
a suction unit head 21, the suction unit head 21 being connected to the suction unit connection tube 11;
a first negative pressure pump 22, the first negative pressure pump 22 being connected to an air extraction tube 23, the air extraction tube 23 being in communication with the reservoir bottle 1 for creating a negative pressure inside the reservoir bottle 1.
Wherein the first negative pressure pump 22 pumps air in the liquid storage bottle through the air suction tube 23 to form negative pressure inside the liquid storage bottle 1, so that the tumor tissue enters the liquid storage bottle 1 through the suction head 21 under the action of the negative pressure.
As a practical way, a switch piece is arranged at the joint of the sample introduction end of the sample introduction pipe 33 and the bottom end of the liquid storage bottle 1, and the switch piece is used for adjusting the communication state of the bottom end of the liquid storage bottle 1 and the sample introduction end of the sample introduction pipe 33.
It can be understood that the tumor tissue sample in the liquid storage bottle 1 enters the centrifugal sleeve 32 through the sample inlet tube 33, and the switch part adjusts the communication state between the bottom end of the liquid storage bottle 1 and the sample inlet end of the sample inlet tube 33, so as to facilitate the recovery of the tumor tissue in the centrifugal sleeve 32 at a proper time. The switch member may be any mechanical switch, and certainly may be any electric switch, which is not limited in this embodiment of the present application, as long as the communication state between the bottom end of the liquid storage bottle 1 and the sample inlet end of the sample inlet tube 33 can be ensured.
Further, the switch is used for adjusting the communication state between the bottom end of the liquid storage bottle 1 and the sample inlet end of the sample inlet pipe 33 under the action of pressure. In the embodiment, the communication state between the bottom end of the liquid storage bottle 1 and the sample inlet end of the sample inlet pipe 33 is adjusted by controlling the switch part through pressure action, so that the structure is simple and the operation is convenient; the position state of the switch member can be adjusted by using the general pressure change, and the communication state between the bottom end of the liquid storage bottle 1 and the sample inlet end of the sample inlet tube 33 can be realized by adjusting the pressure difference between the sample inlet end of the sample inlet tube 33 and the sample outlet end of the sample inlet tube 33.
As a practical means, the opening and closing member includes a movable shutter 61, and one end of the movable shutter 61 is fixed to the sidewall of the bottom end of the liquid storage bottle 1;
the compression air bag 62 is connected with the other end of the movable baffle 61 through a connecting line, and the compression air bag 62 is used for automatically adjusting the tightness state of the connecting line through the internal pressure change so as to adjust the communication state of the bottom end of the liquid storage bottle 1 and the sample inlet end of the sample inlet pipe 33.
Here, the compression bag 62 in this embodiment is connected to the other end of the flap 61 by a connecting wire for controlling the flap 62 to close or open the bottom end of the liquid container 1.
Correspondingly, when the interior of the compression air bag 62 is filled with air, the connecting wire is tightened to shield the movable baffle 61 at the bottom end of the liquid storage bottle 1, and the bottom end of the liquid storage bottle 1 is closed to prevent the bottom end of the liquid storage bottle 1 from being communicated with the sample inlet end of the sample inlet pipe 33;
correspondingly, when the gas in the compression air bag 62 is exhausted, the connecting wire is loosened, so that the other end of the movable baffle 61 is turned down under the action of gravity, and the bottom end of the liquid storage bottle 1 is opened so that the bottom end of the liquid storage bottle 1 is communicated with the sample inlet end of the sample inlet pipe 33;
in the embodiment, the compression air bag 62 is connected with a first pipeline 63 and a second pipeline 64 respectively, the first pipeline 63 is connected with a booster pump 65, and the second pipeline 64 is connected with a second negative pressure pump 66. In the present embodiment, the pressure inside the compression air bag 62 is adjusted by the booster pump 65 and the second negative pressure pump 66, respectively, which is reliable and convenient.
As an implementation manner, the centrifugal casing 32 includes an inner tube and an outer tube sleeved outside the inner tube, a defoaming net 321 and a sterile filter felt 322 are sequentially disposed on a side wall of the inner tube for filtering and collecting tumor tissue, and the outer tube is used for collecting waste liquid.
In this embodiment, the centrifugal sleeve 32 includes an inner tube and an outer tube, which facilitates collection of waste liquid while collecting tumor tissue, and prevents pollution caused by waste liquid that cannot be processed in time.
In a practical manner, the inside of the reservoir bottle 1 is also coated with heparin. This embodiment is favorable to preventing that the sample mixture from solidifying, guarantees subsequent centrifugal separation effect.
The following describes a recovery device of tumor tissue in intracranial high-grade glioma surgery in an embodiment of the present invention with reference to the accompanying drawings.
As shown in fig. 1, the top end of the liquid storage bottle 1 is sealed and is connected with an aspirator connecting pipe 11, a washing liquid conveying pipe 12 and a lysate conveying pipe 41 respectively, the aspirator connecting pipe 11 is connected with an aspirator head 21, the washing liquid conveying pipe 12 is connected with a washing liquid storage bottle 7, the lysate conveying pipe 41 is connected with a red blood cell lysate storage bottle 4, the washing liquid conveying pipe 12 and the lysate conveying pipe 41 are both connected with a peristaltic pump 5, wherein the washing liquid storage bottle 7 and the red blood cell lysate storage bottle 4 are mounted on a bracket, the top end of the liquid storage bottle 1 is also connected with an air suction pipe 23, and the air suction pipe 23 is connected with a first negative pressure pump 22 and is used for forming negative pressure inside the liquid storage bottle 1 so as to suck tumor tissues into the liquid storage bottle 1;
the bottom end opening of the liquid storage bottle 1 is connected with a centrifugal collecting assembly, the centrifugal collecting assembly comprises a centrifugal device 31, a centrifugal sleeve 32 and a sample inlet pipe 33, a movable baffle 61 is arranged between the sample inlet end of the sample inlet pipe 33 and the bottom end of the liquid storage bottle 1, the sample outlet end of the sample inlet pipe 33 is communicated with the centrifugal sleeve 32 and is used for collecting tumor tissues into the centrifugal sleeve 32, the specific centrifugal sleeve 32 comprises an inner pipe and an outer pipe sleeved outside the inner pipe, the side wall of the inner pipe is sequentially provided with a defoaming net 321 and a sterile filter felt 322 and is used for filtering and collecting the tumor tissues, and the outer pipe is used for collecting waste liquid; wherein, one end of the movable baffle 61 is fixed on the side wall of the bottom end of the liquid storage bottle 1, the other end of the movable baffle 61 is connected with the compressed air bag 62 through a connecting line, the compressed air bag 62 is respectively connected with a first pipeline 63 and a second pipeline 64, the first pipeline 63 is connected with a booster pump 65, the second pipeline 64 is connected with a second negative pressure pump 66, under the normal state, the booster pump 65 boosts the compressed air bag 62, the compressed air bag 62 tensions the connecting line, the other end of the movable baffle 61 shields the bottom end of the liquid storage bottle 1, when the tumor tissue sample mixture reaches a certain amount in the liquid storage bottle 1, the peristaltic pump 5 is opened, the red cell lysate is conveyed to the liquid storage bottle 1, after a few minutes, the pipeline of the cleaning solution conveying pipe 12 on the peristaltic pump 5 is opened, the cleaning solution is quickly conveyed to the liquid storage bottle 1, and simultaneously, the second negative pressure pump 66 is opened to evacuate the gas in the compressed air bag 62, the connecting wire is loosened, the movable baffle 61 is turned downwards, so that the tumor tissue sample flows into the centrifugal sleeve 32 through the sampling tube 33; after the tumor tissue sample flows out, the booster pump 65 is started to enable the compression air bag 62 to be filled with air and the connecting line to be tensioned, and the movable baffle 61 is closed; the tumor tissue is collected by centrifugal separation and used for the later diagnosis and treatment process.
In the description of the present application, it is to be understood that the orientation or positional relationship indicated by the directional terms such as "front, rear, upper, lower, left, right", "lateral, vertical, horizontal" and "top, bottom", etc., are generally based on the orientation or positional relationship shown in the drawings, and are used for convenience of description and simplicity of description only, and in the case of not making a reverse description, these directional terms do not indicate and imply that the device or element being referred to must have a particular orientation or be constructed and operated in a particular orientation, and therefore, should not be considered as limiting the scope of the present application; the terms "inner and outer" refer to the inner and outer relative to the profile of the respective component itself.
The above description is only a preferred embodiment of the application and is illustrative of the principles of the technology employed. It will be appreciated by a person skilled in the art that the scope of the invention as referred to in the present application is not limited to the embodiments with a specific combination of the above-mentioned features, but also covers other embodiments with any combination of the above-mentioned features or their equivalents without departing from the inventive concept. For example, the above features may be replaced with (but not limited to) features having similar functions disclosed in the present application.

Claims (10)

1. An apparatus for recovering tumor tissue from intracranial high-grade glioma surgery, comprising:
the top end of the liquid storage bottle is closed and is connected with a suction apparatus connecting pipe and a cleaning solution conveying pipe, and the cleaning solution conveying pipe is connected with a cleaning solution storage bottle and is used for conveying the cleaning solution to the liquid storage bottle;
the discharge end of the negative pressure aspirator is communicated with the aspirator connecting pipe;
the centrifugal collecting assembly comprises a centrifugal device, a centrifugal sleeve arranged inside the centrifugal device and a sample inlet pipe connected to the bottom end of the liquid storage bottle, and the centrifugal sleeve is communicated with the discharge end of the sample inlet pipe.
2. The recovery device according to claim 1, further comprising a red blood cell lysate storage bottle, wherein a lysate delivery pipe is arranged between the red blood cell lysate storage bottle and the liquid storage bottle, and is used for delivering the red blood cell lysate to the liquid storage bottle.
3. The recycling apparatus according to claim 2, further comprising a peristaltic pump connected to the washing liquid conveying pipe and the lysis liquid conveying pipe.
4. The recovery device of any one of claims 1 to 3, wherein the vacuum extractor comprises:
a suction unit head connected to the suction unit connection tube;
the first negative pressure pump is connected with an air exhaust pipe, and the air exhaust pipe is communicated with the liquid storage bottle and is used for forming negative pressure inside the liquid storage bottle.
5. The recycling apparatus according to any one of claims 1 to 3, wherein a switch member is disposed at a connection between the sample introduction end of the sample introduction tube and the bottom end of the liquid storage bottle, and the switch member is used for adjusting a communication state between the bottom end of the liquid storage bottle and the sample introduction end of the sample introduction tube.
6. The recycling apparatus according to claim 5, wherein the switch member is used to adjust the communication state between the bottom end of the liquid storage bottle and the sample inlet end of the sample inlet tube under the action of pressure.
7. The recycling apparatus according to claim 6, wherein a movable baffle plate, one end of which is fixed to a sidewall of a bottom end of the liquid storage bottle;
the compression air bag is connected with the other end of the movable baffle through a connecting wire and used for automatically adjusting the tightness state of the connecting wire through the internal pressure change so as to adjust the communication state of the bottom end of the liquid storage bottle and the sample inlet end of the sample inlet pipe.
8. The recycling apparatus according to claim 6, wherein the compression air bag is connected with a first pipeline and a second pipeline respectively, the first pipeline is connected with a booster pump, and the second pipeline is connected with a second negative pressure pump.
9. The recycling device according to any one of claims 1 to 3, wherein the centrifugal sleeve comprises an inner tube and an outer tube sleeved outside the inner tube, the side wall of the inner tube is sequentially provided with a defoaming net and a sterile filter felt for filtering and collecting tumor tissues, and the outer tube is used for collecting waste liquid.
10. The recovery device according to any of claims 1 to 3, wherein the inside of the reservoir bottle is further coated with heparin.
CN202111317854.9A 2021-11-08 2021-11-08 Recovery unit of tumour tissue in intracranial high-grade glioma art Pending CN113892980A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202111317854.9A CN113892980A (en) 2021-11-08 2021-11-08 Recovery unit of tumour tissue in intracranial high-grade glioma art

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202111317854.9A CN113892980A (en) 2021-11-08 2021-11-08 Recovery unit of tumour tissue in intracranial high-grade glioma art

Publications (1)

Publication Number Publication Date
CN113892980A true CN113892980A (en) 2022-01-07

Family

ID=79193544

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202111317854.9A Pending CN113892980A (en) 2021-11-08 2021-11-08 Recovery unit of tumour tissue in intracranial high-grade glioma art

Country Status (1)

Country Link
CN (1) CN113892980A (en)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5643193A (en) * 1995-12-13 1997-07-01 Haemonetics Corporation Apparatus for collection washing and reinfusion of shed blood
CN2399034Y (en) * 1999-12-31 2000-10-04 陈晨 Disposabe erythrocyte recovering and washing device
CN102151153A (en) * 2011-03-25 2011-08-17 吴成翰 Recycling device of tissue fragments in surgical operation process
CN205286416U (en) * 2015-12-10 2016-06-08 中国人民解放军第四军医大学 Can separate device of retrieving brain tumor tissue
CN209555220U (en) * 2019-01-16 2019-10-29 贵州医科大学第二附属医院 A kind of circulating tumor cell automatic separating apparatus

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5643193A (en) * 1995-12-13 1997-07-01 Haemonetics Corporation Apparatus for collection washing and reinfusion of shed blood
CN2399034Y (en) * 1999-12-31 2000-10-04 陈晨 Disposabe erythrocyte recovering and washing device
CN102151153A (en) * 2011-03-25 2011-08-17 吴成翰 Recycling device of tissue fragments in surgical operation process
CN205286416U (en) * 2015-12-10 2016-06-08 中国人民解放军第四军医大学 Can separate device of retrieving brain tumor tissue
CN209555220U (en) * 2019-01-16 2019-10-29 贵州医科大学第二附属医院 A kind of circulating tumor cell automatic separating apparatus

Similar Documents

Publication Publication Date Title
CN104546021B (en) Clinical laboratory's humor collecting feeding device for inspection
EP2158926A3 (en) Aspirator assembly
CN106902402A (en) A kind of automatic blood transfusion device
CN110358673A (en) Cell separation system and method
US20140081237A1 (en) Hand-held micro-liposuction adipose harvester, processor, and cell concentrator
CN110141690A (en) A kind of internal medicine sputum collecting analysis integrated apparatus
CN113892980A (en) Recovery unit of tumour tissue in intracranial high-grade glioma art
CN212316092U (en) Equipment for extracting adipose-derived stem cells by negative pressure separation
CN105505760B (en) The full-automatic non-closed cell washing system of centrifugation
CN209967162U (en) Consumable box and medical waste collection equipment
CN201572559U (en) Specimen filter
US20140207103A1 (en) Hand-held adipose processor and cell concentrator
CN214877445U (en) Breathe internal medicine nursing and prevent infecting isolating device
CN215194138U (en) Sputum aspirator of tuberculosis branch of academic or vocational study nursing usefulness
CN207227399U (en) A kind of large volume urine DNA/RNA extraction systems
CN111760092A (en) Hydrops processing apparatus that clinical treatment of old patient used
CN209485829U (en) The device of the workable enrichment urine excretion body of hospital and family
CN208838683U (en) A kind of hals,Nasen und Ohrenheilkunde multifunctional ceiling sputum device
CN209172349U (en) One kind being suitable for otorhinolaryngologic sample separator
JPS629852Y2 (en)
CN217375836U (en) Waste collection device for constant-temperature amplification nucleic acid analyzer
CN205017884U (en) Forward type glossy ganoderma spore powder collection device is just torn open to filter screen
CN219579513U (en) Rapid and safe sputum aspirator for emergency internal medicine
CN214551472U (en) Disposable adenoid collecting and filtering device
CN215460678U (en) Respiratory tract cleaning device for nursing critical patients

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination