CN113834704A - Full-automatic rotating material box atomizer type dyeing and piece sealing all-in-one machine - Google Patents
Full-automatic rotating material box atomizer type dyeing and piece sealing all-in-one machine Download PDFInfo
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- CN113834704A CN113834704A CN202010581643.5A CN202010581643A CN113834704A CN 113834704 A CN113834704 A CN 113834704A CN 202010581643 A CN202010581643 A CN 202010581643A CN 113834704 A CN113834704 A CN 113834704A
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- 238000004043 dyeing Methods 0.000 title claims abstract description 65
- 239000000463 material Substances 0.000 title claims abstract description 36
- 238000007789 sealing Methods 0.000 title claims description 26
- 230000007246 mechanism Effects 0.000 claims abstract description 69
- 238000003860 storage Methods 0.000 claims abstract description 58
- 239000006059 cover glass Substances 0.000 claims abstract description 38
- 238000005507 spraying Methods 0.000 claims abstract description 29
- 239000003153 chemical reaction reagent Substances 0.000 claims description 24
- 230000009471 action Effects 0.000 claims description 12
- 230000000903 blocking effect Effects 0.000 claims description 10
- 229920001296 polysiloxane Polymers 0.000 claims description 7
- 229910001220 stainless steel Inorganic materials 0.000 claims description 3
- 239000010935 stainless steel Substances 0.000 claims description 3
- 238000000034 method Methods 0.000 abstract description 21
- 239000007788 liquid Substances 0.000 abstract description 18
- 238000000889 atomisation Methods 0.000 abstract description 14
- 230000008569 process Effects 0.000 abstract description 11
- 239000002699 waste material Substances 0.000 abstract description 5
- 239000011521 glass Substances 0.000 description 24
- 239000003292 glue Substances 0.000 description 17
- 239000000975 dye Substances 0.000 description 6
- 239000007921 spray Substances 0.000 description 6
- 239000002390 adhesive tape Substances 0.000 description 5
- 230000007423 decrease Effects 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 239000007789 gas Substances 0.000 description 5
- 241000252254 Catostomidae Species 0.000 description 4
- 230000006872 improvement Effects 0.000 description 4
- 239000000853 adhesive Substances 0.000 description 3
- 230000001070 adhesive effect Effects 0.000 description 3
- 239000003595 mist Substances 0.000 description 3
- 238000003825 pressing Methods 0.000 description 3
- 239000002912 waste gas Substances 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000012864 cross contamination Methods 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000005538 encapsulation Methods 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 238000007592 spray painting technique Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- 210000003437 trachea Anatomy 0.000 description 1
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/36—Embedding or analogous mounting of samples
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- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
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- Biomedical Technology (AREA)
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- Engineering & Computer Science (AREA)
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Abstract
The invention discloses a full-automatic rotary work bin atomizer type dyeing and mounting integrated machine which comprises an outer frame, a storage box, a rotary platform, a material rack, a slide tray, a slide plate, a spraying mechanism and a cover glass mechanism, wherein the storage box is arranged inside the outer frame, the rotary platform is positioned in the storage box, the material rack is fixedly arranged on the rotary platform, the bottom of the rotary platform is provided with a rotary mechanism for driving the rotary platform to rotate, a plurality of layers of drawable slide trays are arranged inside the material rack from top to bottom, the slide plate can be respectively inserted into the slide tray, and the spraying mechanism and the cover glass mechanism can respectively move along the directions of an X axis, a Y axis and a Z axis. Its whole working process only needs to promote the slide board from the storage box and just accomplishes all dyeings and mounting overall processes, need not remove the slide board to can once only get rid of the unnecessary waste liquid on the slide board through centrifugal mode, the sample piece can both be handled simultaneously in batches with the mounting process simultaneously, and can realize superfine atomization dyeing.
Description
Technical Field
The invention relates to the technical field of medical equipment, in particular to a full-automatic rotary bin atomizer type dyeing and sealing integrated machine.
Background
The existing domestic and foreign pathological sheet and bacterial and cell sheet dyeing modes are 3 types: 99 percent of the dyeing liquid can adopt a hanging basket cylinder dyeing dip-dyeing mode and only one drop dyeing mode of imported Roche, and the other one is a pump pressure spray-dyeing method, wherein an electromagnetic pump is adopted to generate pressure, and a fine hole with the diameter of about 0.1mm and a small groove spray head are used for forming pressure to spray the dyeing liquid. There are 2 types of encapsulation modes for pathology pieces, bacteria and cell pieces: glue dripping + cover glass sheet type and adhesive tape type; after dyeing the glass slide by adopting a hanging basket cylinder dyeing dip-dyeing mode, lifting the dyed hanging basket of the glass slide from the dyeing cylinder by a mechanical arm, transferring the hanging basket of the glass slide to a sealing area by overturning for multiple times, taking out one piece of the glass slide from the hanging basket, dripping glue one by one at a time, sucking a cover glass sealing piece (cover glass piece type), or cutting a small section of adhesive tape on a large roll of adhesive tape and pressing the small section of adhesive tape on the glass slide sealing piece (adhesive tape type), and inserting the other piece into the hanging basket; after the slide is dyed by adopting a drop dyeing mode, the slide plate with 20 slides is pushed out from the box, the slide plate is transferred to different stations for multiple times to realize the drop glue sealing, and then the slide plate is transferred to a storage box.
However, when the hanging basket cylinder dyeing and dip-dyeing method is used, because the reagent cylinder is opened, the reagent volatilizes, the concentration slowly decreases, in addition, the fallen tissue sample fragments can appear in the reagent cylinder for a long time, the dyeing quality of the later dyeing batch can decrease, the cross contamination rate increases, the excellent rate decreases, the stability decreases, when the reagent concentration decreases, a little fresh reagent is added manually by technicians for supplement, the uncertainty is great, meanwhile, the reagent updating completely depends on the manual operation of the technicians, and the health of the technicians is harmful; the drop dyeing method is a new technical innovation, can avoid the defects of a dip dyeing mode, but the drop dyeing mode on the existing market has the following problems: the drop dyeing method is characterized in that a large amount of reagents are dropped in a drop dyeing mode to solve the problem, a slide is arranged in a clamp to enable the surface of the slide to be soaked with the reagents, so that the reagent consumption is large, and meanwhile, a single piece of reagent is dropped after being aligned, so that the time is consumed; the pump pressure spray-painting method needs to adopt an electromagnetic pump to generate pressure (a pump generating large pressure is needed), the cost of the electromagnetic pump is high, one machine needs to use more than ten pumps, the control is complex, in addition, a fine hole and a small groove spray head with the diameter of less than 0.1mm are needed, the dye liquor reagent is thick liquid with crystals and impurities inside, the holes are easy to touch, a large amount of alcohol is needed to wash pipelines every day and off duty, the reagent is needed to fill each pipeline when the machine is used, meanwhile, liquid drops sprayed by the spray head are not fine enough, and superfine mist is not formed.
Disclosure of Invention
In order to solve the problems in the prior art, the invention aims to provide a full-automatic rotary bin atomizer type dyeing and sealing integrated machine which is convenient to use, can complete all dyeing and sealing processes only by pushing a slide plate out of a storage box in the whole working process without moving the slide plate, can remove redundant waste liquid on the slide plate in a centrifugal mode at one time without leaving dead angles, can treat sample pieces in a large batch simultaneously in the dyeing and sealing processes, and can realize superfine atomization dyeing.
In order to achieve the purpose, the invention adopts the following technical scheme:
the invention provides a full-automatic rotary work bin atomizer type dyeing and slide sealing integrated machine which comprises an outer frame, a storage box, a rotary platform, a material rack, slide trays, slide plates, a spraying mechanism and a cover glass mechanism, wherein the storage box is fixedly arranged in the outer frame, the top opening of the storage box is arranged, an openable sealing cover plate is arranged at the opening of the top of the storage box, the rotary platform is positioned in the storage box, the material rack is fixedly arranged on the rotary platform, the bottom of the rotary platform is provided with the rotary mechanism for driving the rotary platform to rotate, the material rack is internally provided with a plurality of layers of slide trays which can be drawn from top to bottom, the slide plates can be respectively inserted into the slide trays, the slide plates are provided with a plurality of slide accommodating grooves at equal intervals, and the spraying mechanism and the cover glass mechanism are positioned at two sides of the storage box, and the spraying mechanism and the cover glass mechanism can move along the directions of an X axis, a Y axis and a Z axis respectively.
The improved slide glass storage box is characterized in that the opposite two sides of the material rack in the storage box are provided with sliding grooves at equal intervals from top to bottom, elastic limiting blocks are arranged in the sliding grooves close to the outlet, the two sides of the glass slide tray can be slidably arranged in the sliding grooves, two sides of the glass slide tray are provided with gear pins, magnetic hook pieces are arranged in the middle of the front side of the glass slide tray, movable gear clamps are arranged on one sides of the outlet of the tray close to the material rack, the movable gear clamps are dislocation gears, and the opposite two sides of the material rack are provided with mechanical arms which can be matched with the glass slide tray to take the glass slide tray out or push the glass slide tray. When the automatic liquid dropping device is used, when a slide on a slide plate needs to be dyed or a glue dripping cover slip is needed, the rack is rotated to the opening to face the direction of a spraying mechanism or the direction of a cover slip mechanism through the rotating mechanism, the slide tray is pulled out of the rack through the action of the mechanical arm and the magnetic hook, after the slide tray is pulled out in place, the elastic limiting block at the outlet of the sliding groove is clamped with the blocking pins at the two sides of the slide tray, so that the slide on the slide tray is prevented from moving when the glue dripping cover slip works, meanwhile, the movable blocking pins are hooked by the mechanical arm to lift and block and stagger the slide tray, the movable blocking pins block the slide tray when centrifugally liquid is thrown off or the slide tray rotates to other stations to prevent the slide tray from being thrown off, and the slide tray can be pulled and pulled.
The further improvement is that the glass slide tray is of a hollow-out structure, and the material rest is of a linear frame structure. The rotary platform is driven to rotate by the rotary mechanism, and redundant waste liquid sprayed on the slide, the slide tray and the material rack in the dyeing process can be conveniently thrown away by adopting a centrifugal method without dead angles;
the improved structure is characterized in that the atomizing mechanism comprises an atomizing nozzle, the atomizing nozzle comprises a cylindrical outer pipe, an inner pipe, an air pipe joint, a control valve and an air compressor, a hollow inner cavity is formed inside the outer pipe, the outer pipe is a hollow circular pipe, one end of the outer pipe gradually shrinks inwards to form a small hole, the other end of the outer pipe is in threaded connection with the air pipe joint, a through hole communicated with the hollow inner cavity is formed inside the air pipe joint, a first port communicated with the through hole and used for air intake is formed in the air pipe joint, a second port used for inserting the inner pipe is further arranged on the air pipe joint, the first port is communicated with the air compressor through a pipeline and the control valve, the inner pipe is inserted into the through hole in the air pipe joint and the hollow inner cavity in the outer pipe through the second port, and one end of the inner pipe, which is positioned outside the air pipe joint, is communicated with the reagent bottle through a silicone tube and the control valve, one end opening of the inner pipe is close to the small hole of the outer pipe, but is at a certain distance from the small hole. When the device is used, compressed air enters the hollow inner cavity of the outer tube through the air pipe joint through the air compressor and is sprayed out from the small hole of the outer tube, one end of the outer tube is gradually contracted inwards to form a small hole, the air flow is gradually thinned when being sprayed out, the air flow is accelerated, so that a vacuum area is formed at the small hole outlet of the outer tube to generate a Venturi body effect, one end of the outlet of the inner tube is just positioned at the vacuum area, the other end of the inner tube is connected with a reagent bottle through a silicone tube, liquid is adsorbed under the action of negative pressure of the vacuum area to be sprayed onto the surface of a slide in an ultrafine atomization mode, ultrafine atomization dyeing is realized, the adhesive force of a dyeing liquid and the slide is strong, the reagent is saved, and when the device is used, the atomization nozzle can sweep and spray a plurality of slides without aiming at the drip dyeing, and the time is saved; and the reagent bottle is sealed and is drawn out by an independent silicone tube for atomization dyeing, so that the stability of the concentration of the reagent in use is ensured.
The improved atomizing nozzle further comprises a spherical structure, one side of the spherical structure is connected with a sleeve through a fixing piece, the sleeve is sleeved on the outer side of the outer pipe, the spherical structure is right opposite to a small hole formed by shrinkage of one end of the outer pipe, and a certain gap is reserved between the spherical structure and the outer pipe. Through setting up spherical structure, the fine mist through preliminary thinning processing in the inner tube is beaten and is thinned for the second time on spherical structure, has further guaranteed to carry out superfine atomization processing's effect to the dyeing liquid.
The further improvement lies in that the inner pipe can be made of anticorrosive materials such as stainless steel, and the inner pipe comprises 2 types: one is a small pipe with equal inner and outer diameters, and the other is a small pipe with a conical port and an outer wall.
The further improvement is that the inner diameter of the inner pipe is unchanged, and the outer diameter pipe wall of one end of the inner pipe close to the small hole of the outer pipe gradually shrinks inwards to form a conical structure.
The cover glass mechanism is further improved in that the cover glass mechanism comprises a cover glass assembly, the cover glass assembly comprises a plurality of groups of suckers, each group of suckers comprises two suckers, and the surfaces of the two suckers are not located on the same horizontal plane. Through the arrangement, bubbles in the glue solution can be conveniently discharged in the process of pressing down the cover glass.
In a further improvement, the cover glass mechanism further comprises a cover glass storage box, the cover glass storage box is positioned on one side of the sucker, and the cover glass storage box can extend out to the position below the sucker under the action of the sliding assembly. Through setting up, the glass lid storage box can stretch out to the sucking disc below at sliding assembly's effect, also can contract back fast, and sliding assembly can adopt the cylinder.
The improved storage box is characterized in that a first cover plate and a second cover plate which can be opened and closed are arranged at the opening of the top of the storage box, the first cover plate and the second cover plate can seal the top of the storage box, a sealing door is arranged at the front of the storage box, and the side walls of two opposite sides in the storage box are respectively communicated with a hot air pipe and an air suction pipe. When spraying mechanism during operation, seal the storage box through first apron and second apron, the glass cover mechanism rises and is located the outside, prevents that dye liquor from polluting glass cover mechanism, and after the spraying dyeing is accomplished, takes away the waste gas in the storage box through hot-blast main and aspiration channel, accomplishes dry clean work.
Compared with the prior art, the invention has the following beneficial effects:
(1) the drawing type slide tray working method is adopted, the slide tray can be drawn out or pushed into the material rack through the interaction of the mechanical arm and the slide tray through the material rack, the slide tray, the slide plate and the mechanical arm which are arranged in the storage box, the slide on each layer of slide tray can be dyed and mounted, the sample slide or the slide tray does not need to be transferred to other stations, and the use is convenient;
(2) the rotary platform and the rotary mechanism are arranged, so that the material rack can be driven to be transferred to the direction of the spraying mechanism or face the cover glass mechanism for dyeing or glue dripping and covering, the glass slide tray is arranged to be of a hollow-out structure, the material rack is arranged to be of a linear frame structure, the rotary mechanism can drive the material rack to rotate, waste liquid sprayed on the glass slide, the glass slide tray and the material rack in the dyeing process can be conveniently thrown away by a centrifugal method, and dead angles are not left;
(3) the first cover plate and the second cover plate which can be opened and closed are arranged at the opening at the top of the storage box, when the spraying mechanism works, the storage box is sealed through the first cover plate and the second cover plate, and the cover glass mechanism is lifted to be positioned outside during dyeing, so that the dye solution is prevented from polluting the cover glass mechanism;
(4) dyeing and mounting process can both handle sample slide in batches simultaneously, save time, and through setting up atomizing nozzle, through cylindric outer tube, inner tube, the trachea joint in the atomizing nozzle mutually support, moreover, the steam generator is simple in structure, the cost is lower, liquid is sprayed to the slide on the surface with superfine atomization, superfine atomization dyeing has been realized, the adhesive force of dyeing liquor and slide is strong, save reagent, when using, atomizing nozzle can sweep many slides and spout, it dyes to aim at a drop without a drop, save time.
Drawings
The invention is described in further detail below with reference to specific embodiments and with reference to the following drawings.
FIG. 1 is a perspective view of a full-automatic rotary bin atomizer type dyeing and mounting integrated machine according to the present invention;
FIG. 2 is a perspective view of the full-automatic rotary bin atomizer type dyeing and sealing integrated machine of the invention after a shell of a storage box is removed;
FIG. 3 is a schematic view of the cover glass mechanism of the present invention from top to bottom;
FIG. 4 is a schematic view of the structure of the spraying mechanism of the present invention;
FIG. 5 is a schematic view showing the structure of a slide tray according to the present invention;
FIG. 6 is a schematic structural view of a frame-shaped frame body according to the present invention;
FIG. 7 is a schematic view showing the internal structure of an atomizing nozzle in accordance with the present invention;
FIG. 8 is a schematic view of an atomizing nozzle according to the present invention;
FIG. 9 is a schematic view of an atomizing nozzle provided with a spherical structure according to the present invention;
FIG. 10 is a schematic view of the cover glass mechanism of the present invention from bottom to top
FIG. 11 is a schematic view of the structure of the glue dispensing assembly and the lid assembly of the present invention;
wherein, the specific reference numbers are: the outer frame 1, the bottom plate 2, the storage box 3, the sealing door 4, the first cover plate 5, the second cover plate 6, the rack 7, the chute 8, the slide tray 9, the slide accommodating groove 10, the magnetic hook 11, the support plate 12, the first guide rail 13, the first driving component 14, the second guide rail 15, the second driving component 16, the fixing seat 17, the driving pulley 18, the driven pulley 19, the synchronous belt 20, the motor 21, the spraying mechanism 22, the first support 23, the first slide rail 24, the first slider 25, the first lifting seat 26, the nozzle fixing seat 27, the atomizing nozzle 28, the outer tube 29, the hollow inner cavity 30, the inner tube 31, the air tube connector 32, the through hole 33, the first port 34, the second port 35, the spherical structure 36, the fixing part 37, the sleeve 38, the cover glass mechanism 39, the second support 40, the second slide rail 41, the second slider 42, the second lifting seat 43, the glue dropping tube 46, the suction cup 47, the movable stopper 48, a stopper pin 49, a slide plate 50, a rotary platform 51, a rotary motor 52, and a cover glass storage box 53.
Detailed Description
The embodiment of the invention discloses a full-automatic rotary bin atomizer type dyeing and sealing integrated machine, which comprises an outer frame 1, a bottom plate 2, a storage box 3, a supporting plate 12, a first sliding mechanism, a spraying mechanism 22 and a cover glass mechanism 39, wherein the outer frame 1 is fixedly arranged on the bottom plate 2, pulleys are arranged at the bottom of the bottom plate 2, the storage box 3 is fixedly arranged inside the outer frame 1, the supporting plate 12 is fixedly arranged at the top of the outer frame 1 along two sides of the length direction, the first sliding mechanism is arranged on the supporting plate 12, and the spraying mechanism 22 and the cover glass mechanism 39 respectively move along the length direction of the outer frame 1 under the action of the first sliding mechanism. The front side of the storage box 3 is provided with a sealing door 4, the top of the storage box 3 is provided with an opening, the opening at the top of the storage box 3 is provided with a first cover plate 5 and a second cover plate 6 which can be opened and closed, the first cover plate 5 and the second cover plate 6 can seal the top of the storage box 3, the side walls at two opposite sides in the storage box 3 are respectively communicated with a hot air pipe and an air suction pipe, when the spraying mechanism 22 works, the storage box 3 is sealed through the first cover plate 5 and the second cover plate 6, the cover glass mechanism 39 is lifted to be positioned outside to prevent the dye solution from polluting the cover glass mechanism 39, and after spraying and dyeing are finished, the waste gas in the storage box 3 is pumped away through the hot air pipe and the air suction pipe to finish drying and cleaning work; as shown in fig. 2, 5 and 6, a material rack 7, a slide tray 9 and a manipulator are arranged in the storage box 3, two opposite sides of the material rack 7 are provided with a chute 8 at equal intervals from top to bottom, an elastic limit block is arranged in the chute 8 close to the outlet, two sides of the slide tray 9 are slidably arranged in the chute 8, two sides of the slide tray 9 are provided with a stop pin 49, a magnetic hook 11 is arranged in the middle of the front side of the slide tray 9, a slide plate 50 can be respectively inserted into the slide tray 9, a plurality of slide accommodating grooves 10 are arranged on the slide plate 50 at equal intervals, one side of the material rack 7 close to the outlet of the tray is provided with a movable stop card 48, the movable stop card 48 is a dislocation stop, two opposite sides of the material rack 7 are provided with a manipulator which is matched with the slide tray 9 and can be drawn out or pushed in the same, the magnetic hook 11 is arranged in the middle of the front side of the slide tray 9, and the manipulator is provided with an electromagnet which can be magnetically matched with the magnetic hook 11, a rotating platform 51 is arranged below the material rack 7, a rotating mechanism capable of driving the rotating platform 51 to rotate is arranged at the bottom of the rotating platform 51, the rotating mechanism is a rotating motor 52 in the embodiment, the glass slide tray 9 is of a hollow-out structure, and the material rack 7 is of a linear frame structure. Through the arrangement of the rotary platform 51 and the rotary mechanism, when the slide on the slide plate 50 needs to be dyed or coated with glue, the rack 7 is rotated to the opening to face the direction of the spraying mechanism 22 or the direction of the cover glass mechanism 39 through the rotary mechanism, the slide tray 9 is pulled out from the rack 7 through the action of the mechanical arm and the magnetic hook 11, after the slide tray is pulled out in place, the elastic limiting block at the outlet of the sliding groove 8 is clamped with the blocking pins 49 at two sides of the slide tray 9, meanwhile, the movable blocking card 48 is hooked by the mechanical arm to perform lifting action to block and stagger the slide tray 9, the movable blocking card 48 blocks the slide tray 9 to prevent the slide tray 9 from being thrown out when centrifugally throwing liquid or rotating to other stations, and the slide tray 9 can be pulled and pulled when staggering in other stations. The glass slide tray 9 is arranged to be a hollow structure, the material rack 7 is of a linear frame structure, the rotating mechanism can drive the glass slide tray 9 in the material rack 7 to rotate, and the glass slide, the glass slide tray 9 and waste liquid sprayed on the material rack 7 in the dyeing process can be conveniently thrown away by adopting a centrifugal method without dead angles.
As shown in fig. 4, the spraying mechanism 22 includes a first bracket 23, a first slide rail 24, a first slider 25, a first lifting seat 26, a first connecting plate, and a nozzle assembly, the first bracket 23 is disposed on the support plate 12, the first bracket 23 is perpendicular to the length direction of the outer frame 1, the first bracket 23 can move along the length direction of the outer frame 1 under the action of the first sliding mechanism, the first slide rail 24 is disposed on the first bracket 23 along the length direction, the first slider 25 is slidably disposed on the first slide rail 24, the first lifting seat 26 is disposed along the vertical direction, the back of the first lifting seat 26 is connected to the first slider 25 through the first connecting plate, the nozzle assembly is slidably disposed on the first lifting seat 26, and the nozzle assembly can move up and down along the first lifting seat 26. Through setting up, realized carrying out the control of upper and lower, left and right sides and back-and-forth movement to the shower nozzle subassembly, need not remove slide tray 9 at the dyeing in-process, and can handle the sample simultaneously in batches, improve work efficiency.
The shower nozzle subassembly includes nozzle fixing base 27 and atomizing nozzle 28, and 27 one sides of nozzle fixing base slide to set up on first lift seat 26, and a plurality of mounting grooves have been seted up to equidistant on the nozzle fixing base 27, and the mounting groove is embedded to be equipped with atomizing nozzle 28. As shown in fig. 7 and 8, the atomizing nozzle 28 includes a cylindrical outer tube 29, an inner tube 31, a gas tube connector 32 and an air compressor, a hollow inner cavity 30 is formed inside the outer tube 29, one end of the outer tube 29 gradually shrinks inwards to form a small hole, the other end of the outer tube 29 is in threaded connection with the gas tube connector 32, a through hole 33 communicated with the hollow inner cavity 30 is formed inside the gas tube connector 32, a first port 34 communicated with the through hole 33 and used for air intake is formed on the gas tube connector 32, a second port 35 used for inserting the inner tube 31 is further formed on the gas tube connector 32, the first port 34 is communicated with the air compressor through a pipeline and a control valve, the inner tube 31 is made of stainless steel, the inner tube 31 can be set to be a small tube with equal inner diameter or the inner tube 31 is set to have a constant inner diameter, and the outer diameter tube wall near the small hole of the outer tube 29 gradually shrinks inwards to form a conical structure, in this embodiment, the inner tube 31 is a small tube with equal inner diameter, the inner tube 31 is inserted into the through hole 33 in the air pipe connector 32 and the hollow inner cavity 30 in the outer tube 29 through the second port 35, and one end of the inner tube 31, which is positioned outside the air pipe connector 32, is communicated with the reagent bottle through the silicone tube and the control valve. When the device is used, compressed air enters the hollow inner cavity 30 of the outer tube 29 through the air pipe joint 32 and is sprayed out from the small hole of the outer tube 29, one end of the outer tube 29 gradually shrinks inwards to form a small hole, the air flow is sprayed out from a thick thin shape, the air flow is accelerated to form a vacuum area at the small hole outlet of the outer tube 29, one end of the outlet of the inner tube 31 is just positioned at the vacuum area, the other end of the inner tube 31 is connected with a reagent bottle through a silicone tube, liquid is adsorbed under the action of negative pressure of the vacuum area to be sprayed onto the surface of a slide in an ultrafine atomization mode, ultrafine atomization dyeing is realized, the adhesive force of dye liquid and the slide is strong, the reagent is saved, when the device is used, the atomization nozzle 28 can sweep and spray a plurality of slides, one drop is not used for aiming at the drip dyeing, and the time is saved; and the reagent bottle is sealed and is drawn out by an independent silicone tube for atomization dyeing, so that the stability of the concentration of the reagent in use is ensured.
As shown in fig. 9, the atomizing nozzle 28 further includes a spherical structure 36, one side of the spherical structure 36 is connected to a sleeve 38 through a fixing member 37, the sleeve 38 is sleeved outside the outer tube 29, the spherical structure 36 is opposite to a small hole formed by shrinking one end of the outer tube 29, and a certain gap is reserved between the spherical structure 36 and the outer tube 29. Through setting up spherical structure 36, the fine mist through preliminary thinning processing in inner tube 31 is beaten and is thinned for the second time on spherical structure 36, has further guaranteed to carry out superfine atomization processing's effect to the dyeing liquor.
As shown in fig. 3, the cover glass mechanism 39 includes a second support 40, a second slide rail 41, a second slider 42, a second lifting seat 43, a second connecting plate, a glue spraying assembly and a cover plate assembly, the second support 40 is disposed on the support plate 12, the second support 40 is perpendicular to the length direction of the outer frame 1, the second support 40 can move along the length direction of the outer frame 1 under the action of the first sliding mechanism, the second slide rail 41 is disposed on the second support 40 along the length direction, the second slider 42 is slidably disposed on the second slide rail 41, the second lifting seat 43 is disposed along the vertical direction, the back of the second lifting seat 43 is connected with the second slider 42 through the second connecting plate, a third connecting plate is slidably disposed on the second lifting seat 43, and the glue spraying assembly and the cover plate assembly are disposed outside the third connecting plate. Through setting up, realized spouting about, about and the back-and-forth movement of gluey subassembly and cover plate subassembly. Wherein, as shown in fig. 10 and 11, the glue spraying component uses the structure that has spraying glue in the prior art, the glue spraying component in this embodiment can select a plurality of parallel arrangement's glue dripping pipe 46 for spraying glue solution to the slide, the cover slip component is used for pressing the cover slip on the slide, the cover slip component can select the cover slip component that is applicable to the slide lid field among the prior art for use, the cover slip component in this embodiment selects a plurality of groups of sucking discs, wherein every group sucking disc includes two sucking discs 47, the sucking disc face of two sucking discs 47 in every group is not located same horizontal plane, the cover slip component still includes cover slip storage box 53, cover slip storage box 53 is located sucking disc one side, cover slip storage box 53 can stretch out to sucking disc 47 below under the effect of sliding component, the sliding component can adopt the cylinder.
The first sliding mechanism comprises two first guide rails 13, two first sliding blocks, a first driving assembly 14, two second guide rails 15, two second sliding blocks and a second driving assembly 16, the first guide rails 13 and the second guide rails 15 are respectively arranged at two ends of the top of the supporting plate 12 along the length direction, two ends of a first support 23 in the spraying mechanism 22 are respectively in sliding connection with the first guide rails 13 through the first sliding blocks, the first support 23 can move along the length direction of the first guide rails 13 under the action of the first driving assembly 14, two ends of a second support 40 in the cover glass mechanism 39 are respectively in sliding connection with the second guide rails 15 through the second sliding blocks, and the second support 40 can move along the length direction of the second guide rails 15 under the action of the second driving assembly 16. First drive assembly 14 is the same with second drive assembly 16 structure, first drive assembly 14 includes fixing base 17, driving pulley 18, driven pulley 19, hold-in range 20 and motor 21, 12 both ends of backup pad are the fixed fixing base 17 that is provided with respectively, it is provided with driving pulley 18 and driven pulley 19 to transversely rotate respectively on two fixing bases 17, 18 one end of driving pulley is connected with the motor 21 drive, driving pulley 18 and the 19 outside of driven pulley are equipped with hold-in range 20, 23 one side tops of first support are connected with hold-in range 20 through the installed part.
The present invention has been described in terms of specific examples, which are provided to aid understanding of the invention and are not intended to be limiting. For a person skilled in the art to which the invention pertains, several simple deductions, modifications or substitutions may be made according to the idea of the invention.
Claims (10)
1. A full-automatic rotary bin atomizer type dyeing and mounting integrated machine is characterized by comprising an outer frame, a storage box, a rotary platform, a material rack, a slide tray, a slide plate, a spraying mechanism and a cover glass mechanism, wherein the storage box is fixedly arranged inside the outer frame, an opening at the top of the storage box is arranged, an openable sealing cover plate is arranged at an opening at the top of the storage box, the rotary platform is positioned in the storage box, the material rack is fixedly arranged on the rotary platform, a rotary mechanism for driving the rotary platform to rotate is arranged at the bottom of the rotary platform, the material rack is internally provided with a plurality of layers of drawable slide trays from top to bottom, the slide plate can be respectively inserted into the slide trays, a plurality of slide accommodating grooves are formed in the slide plate at equal intervals, and the spraying mechanism and the cover glass mechanism are positioned on two sides of the storage box, and the spraying mechanism and the cover glass mechanism can move along the directions of an X axis, a Y axis and a Z axis respectively.
2. The full-automatic rotary bin atomizer type dyeing and sealing integrated machine according to claim 1, wherein sliding grooves are formed in the two opposite sides of the material rack in the storage box at equal intervals from top to bottom, an elastic limiting block is arranged in the sliding grooves close to an outlet, two sides of the slide tray are slidably arranged in the sliding grooves, blocking pins are arranged on two sides of the slide tray, a magnetic hook is arranged in the middle of the front side of the slide tray, a movable blocking card is arranged on one side of the material rack close to the outlet of the tray, the movable blocking card is a dislocation blocking, and mechanical arms which are matched with the slide tray to draw out or push the slide tray are arranged on two opposite sides of the material rack.
3. The full-automatic rotary bin atomizer type dyeing and sealing integrated machine according to claim 2, wherein the slide tray is of a hollow-out structure, and the material rest is of a linear frame structure.
4. The full-automatic rotary bin atomizer type dyeing and sealing integrated machine according to claim 1, wherein the spraying mechanism comprises an atomizing nozzle, the atomizing nozzle comprises a cylindrical outer tube, an inner tube, a gas tube joint, a control valve and an air compressor, a hollow inner cavity is formed inside the outer tube, the outer tube is a hollow circular tube, one end of the outer tube gradually shrinks inwards to form a small hole, the other end of the outer tube is in threaded connection with the gas tube joint, a through hole communicated with the hollow inner cavity is formed inside the gas tube joint, a first port communicated with the through hole and used for gas inlet is formed on the gas tube joint, a second port used for inserting the inner tube is further arranged on the gas tube joint, the first port is communicated with the air compressor through a pipeline and the control valve, and the inner tube is inserted into the through hole in the gas tube joint and the hollow inner cavity in the outer tube through the second port, the inner tube is positioned at one end outside the air pipe joint and is communicated with the reagent bottle through a silicone tube and a control valve.
5. The full-automatic rotary bin atomizer type dyeing and sealing integrated machine according to claim 4, wherein the atomizing nozzle further comprises a spherical structure, one side of the spherical structure is connected with a sleeve through a fixing part, the sleeve is sleeved outside the outer tube, the spherical structure is right opposite to a small hole formed by shrinkage of one end of the outer tube, and a certain gap is reserved between the spherical structure and the outer tube.
6. The fully automatic rotary bin atomizer dyeing and sealing integrated machine according to claim 4 or 5, wherein the inner tube is stainless steel and the inner tube is a small tube with a constant inner diameter.
7. The full-automatic rotary bin atomizer type dyeing and sealing integrated machine according to claim 4 or 5, wherein the inner diameter of the inner tube is unchanged, and the outer diameter tube wall of one end of the inner tube close to the small hole of the outer tube is gradually shrunk inwards to form a conical structure.
8. The fully automatic rotary bin atomizer type dyeing and mounting all-in-one machine according to claim 1, wherein the cover slip mechanism comprises a cover slip assembly, the cover slip assembly comprises a plurality of groups of suction cups, wherein each group of suction cups comprises two suction cups, and the suction cup surfaces of the two suction cups are not located on the same horizontal plane.
9. The fully automatic rotary bin atomizer-type dyeing and mounting all-in-one machine according to claim 8, wherein said cover glass mechanism further comprises a cover glass storage box, said cover glass storage box is located on one side of said suction cup, said cover glass storage box can be extended to below said suction cup under the action of said sliding assembly.
10. The full-automatic rotary bin atomizer type dyeing and sealing integrated machine according to claim 1, wherein a first cover plate and a second cover plate which can be opened and closed are arranged at an opening at the top of the storage box, the first cover plate and the second cover plate can seal the top of the storage box, a sealing door is arranged at the front of the storage box, and a hot air pipe and an air suction pipe are respectively communicated and arranged on the side walls of two opposite sides in the storage box.
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CN114907455A (en) * | 2022-06-23 | 2022-08-16 | 中国人民解放军东部战区总医院 | Separation device for severe coronavirus protein |
CN116358975A (en) * | 2023-04-14 | 2023-06-30 | 中国人民解放军总医院第三医学中心 | Portable pathology slide automatic sealing machine |
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