CN113648113A

CN113648113A - Degradable support

Info

Publication number: CN113648113A
Application number: CN202110947256.3A
Authority: CN
Inventors: 郭利斌
Original assignee: Shanghai Heyin Enterprise Management Consulting Center
Current assignee: Nanjing Youdebang Medical Technology Co ltd
Priority date: 2021-08-18
Filing date: 2021-08-18
Publication date: 2021-11-16
Anticipated expiration: 2041-08-18
Also published as: CN113648113B

Abstract

The invention discloses a degradable stent, which comprises a plurality of closed rings arranged at intervals along the axial direction, wherein the closed rings can be radially contracted and contracted, two adjacent closed rings are connected through a plurality of bridge rods uniformly arranged along the circumferential direction, and a plurality of through holes are uniformly arranged on the bridge rods along the axial direction; the closed ring and the bridge rod are made of polylactic acid, polylactic acid-glycolic acid copolymer, zinc, magnesium, iron, zinc alloy, magnesium alloy or degradable polymer. The degradable stent has good supporting performance.

Description

Degradable support

Technical Field

The invention relates to the technical field of intravascular stents, in particular to a degradable stent.

Background

The intravascular stent is characterized in that an internal stent is placed in a lesion section on the basis of the expansion forming of a lumen saccule so as to achieve the purposes of supporting a blood vessel at a stenotic occlusion section, reducing the elastic retraction and reshaping of the blood vessel and keeping the blood flow of a lumen unobstructed. Some stents also have the effect of preventing restenosis. Mainly divided into coronary stents, cerebral vascular stents, renal artery stents, aortic stents, etc.

The existing blood vessel stent has poor supporting performance, and easily generates defects of collapse, deformation and the like under the action of external force, such as the processes of pressing and releasing, thereby forming potential threats to the health of patients.

Disclosure of Invention

The invention aims to provide a degradable stent, which solves the problems in the prior art and improves the supporting performance of a vascular stent.

In order to achieve the purpose, the invention provides the following scheme:

the invention provides a degradable stent, which comprises a plurality of closed rings arranged at intervals along the axial direction, wherein the closed rings can be radially contracted and contracted, two adjacent closed rings are connected through a plurality of bridge rods uniformly arranged along the circumferential direction, and a plurality of through holes are uniformly arranged on the bridge rods along the axial direction; the closed ring and the bridge rod are made of polylactic acid, polylactic acid-glycolic acid copolymer, zinc, magnesium, iron, zinc alloy, magnesium alloy or degradable polymer.

Preferably, a plurality of the closed rings are uniformly arranged in the axial direction.

Preferably, the closed ring comprises a plurality of end-to-end combined units, each combined unit comprises a plurality of connecting rods which are connected in sequence, and two connected connecting rods are inclined relatively; the combined unit is in a curve shape; the combination units in two adjacent closed rings correspond to each other one by one, the joint of two adjacent combination units in the same closed ring is connected with one bridge rod, the two corresponding combination units are connected through the two bridge rods, and the two corresponding combination units and the two bridge rods between the two corresponding combination units form a closed contour.

Preferably, a plurality of closed outlines in the same degradable stent are in a regular 8 shape, an oblique 8 shape, a rhombus-like shape or an S shape; the shape of the different said closed contours is the same or different.

Preferably, the central angle occupied by the closed contour in the circumferential direction of the degradable stent ranges from 10 degrees to 120 degrees, and the number of the closed contour in the axial direction of the degradable stent ranges from 6 per centimeter to 12 per centimeter.

Preferably, two adjacent connecting rods in one combined unit are further connected through an arc-shaped rod, and the two adjacent connecting rods and the arc-shaped rod form a rhombus-like closed structure; when the degradable stent is pressed and held, the arc-shaped rods can be inosculated with the corresponding connecting rods.

Preferably, an inner wall at a corner of each of the closed contours is provided with an arc-shaped recess, and the arc-shaped recess is formed through a cutting process.

Preferably, the connecting rods are both curved rods, and the protruding directions of two adjacent connecting rods are opposite.

Preferably, each bridge rod is provided with a plurality of developing marks.

Compared with the prior art, the invention has the following technical effects:

the degradable stent has good supporting performance. The degradable stent has stronger radial supporting force, stability and trafficability characteristic by arranging the closed contour, can eliminate stress by adding the bridge rod with the through hole, obtains better flexibility and deformation adaptability, ensures that the stent is not easy to have the defects of collapse, deformation and the like in the processes of pressure holding and releasing, more stably supports the vessel wall, improves the supporting performance of the stent in the service life after implantation, simultaneously increases the surface coverage rate and reduces the risk of plaque falling off of a lesion part.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings needed in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings without creative efforts.

FIG. 1 is a schematic structural diagram of a degradable stent according to an embodiment of the present invention;

FIG. 2 is a schematic plane view of a degradable stent according to an embodiment of the present invention;

FIG. 3 is an enlarged view of a portion of FIG. 2;

FIG. 4 is a schematic structural diagram of a second degradable stent according to an embodiment of the invention;

FIG. 5 is a schematic structural diagram of a third degradable stent according to an embodiment of the invention;

FIG. 6 is a schematic structural diagram of a degradable stent according to an embodiment of the present invention;

FIG. 7 is a schematic structural diagram of a five-degradable stent according to an embodiment of the invention;

wherein: 100. a degradable scaffold; 1. a closed ring; 2. a bridge rod; 3. a combination unit; 4. a closed contour; 5. an arcuate bar; 6. a first connecting rod; 7. a second connecting rod; 8. a third connecting rod; 9. a fourth connecting rod; 10. a first curved bar; 11. a second curved bar; 12. a third crank; 13. a fourth crank; 14. an arc-shaped recess.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be obtained by a person skilled in the art without inventive effort based on the embodiments of the present invention, are within the scope of the present invention.

In order to make the aforementioned objects, features and advantages of the present invention comprehensible, embodiments accompanied with figures are described in further detail below.

Example one

As shown in fig. 1 to 3: the embodiment provides a degradable stent 100, including a plurality of closed rings 1 that set up along the axial evenly, interval, closed ring 1 can radially scale, and the diameter value range that closed ring 1 radially can expand and scale is 0.5mm-20mm, and the value range of the total length of degradable stent 100 is: 2mm-200mm, two adjacent closed rings 1 are connected through a plurality of bridge rods 2 which are uniformly arranged in the circumferential direction, a plurality of through holes are uniformly formed in the bridge rods 2 in the axial direction, the through holes are circular, square, slotted hole-shaped or polygonal, and through the arrangement of the bridge rods 2 with the through holes, stress can be eliminated, and better flexibility and deformation adaptability can be obtained; the materials of the closed ring 1 and the bridge rod 2 are polylactic acid, polylactic acid-glycolic acid copolymer, zinc, magnesium, iron, zinc alloy, magnesium alloy or degradable polymer.

The closed ring 1 comprises a plurality of end-to-end combined units 3, each combined unit 3 comprises four connecting rods which are sequentially connected and are respectively a first connecting rod 6, a second connecting rod 7, a third connecting rod 8 and a fourth connecting rod 9, the connecting rods can be in one or more of a straight rod shape, an S shape, a V shape, an L shape and an arc shape, and the two connected connecting rods are relatively inclined; in this embodiment, the combination unit 3 is curved and has a plurality of continuous S-shaped structures, so that the passing ability of the bracket is increased in the use process of the bracket, the first connecting rod 6, the second connecting rod 7, the third connecting rod 8 and the fourth connecting rod 9 are all curved rods, and the protruding directions of two adjacent connecting rods are opposite. And any two adjacent connecting rods in the first connecting rod 6, the second connecting rod 7, the third connecting rod 8 and the fourth connecting rod 9 are symmetrically distributed, and the symmetry axis is a straight line which passes through the connecting point of the two adjacent connecting rods and is parallel to the axial direction of the degradable support 100.

The combination units 3 in two adjacent closed rings 1 correspond to each other one by one, the joint of two adjacent combination units 3 in the same closed ring 1 is connected with a bridge rod 2, the two corresponding combination units 3 are connected through the two bridge rods 2, the two corresponding combination units 3 and the two bridge rods 2 between the two corresponding combination units 3 form a closed contour 4, and in this embodiment, the closed contour 4 is S-shaped.

The central angle of the closed contour 4 in the circumferential direction of the degradable stent 100 ranges from 10 degrees to 120 degrees, and the number of the closed contour 4 in the axial direction of the degradable stent 100 ranges from 6 to 12 per centimeter.

Two adjacent connecting rods in one combined unit 3 are also connected through an arc-shaped rod 5, and the two adjacent connecting rods and the arc-shaped rod 5 form a rhomboid closed structure; when pressing and holding degradable support 100, two connecting rods that are provided with arc pole 5 can be close to each other, arc pole 5 is compressed tightly simultaneously, final arc pole 5 can coincide with two connecting rods that correspond, promptly the profile of arc pole 5 need with the profile phase-match of these two connecting rods, in order to guarantee that final arc pole 5 can coincide with two connecting rods that correspond, the support is whole when pressing and holding prevents collapsing, the ability of preapring for an unfavorable turn of events shape has been improved, improve the support performance in the back service life of support implantation, the surface coverage rate has still been increased simultaneously, the risk that pathological change position plaque drops has been reduced. It should be noted that, in the present embodiment, the arc-shaped rods 5 are themselves symmetrical about the symmetry axis between the two corresponding connecting rods.

Each bridge rod 2 is provided with developing marks, and the number of the developing marks is 2-10.

Example two

As shown in fig. 4: the present embodiment provides a degradable stent 100, and the structure of the degradable stent 100 of the present embodiment is substantially the same as the structure of the degradable stent 100 of the first embodiment, except that: in this embodiment, the first curved bar 10, the second curved bar 11, the third curved bar 12 and the fourth curved bar 13 which are connected in sequence are adopted to replace the curved bar 5 in the first embodiment, and a combination body formed by combining the first curved bar 10, the second curved bar 11, the third curved bar 12 and the fourth curved bar 13 is symmetrical about a symmetry axis between the two corresponding connecting bars.

EXAMPLE III

As shown in fig. 5: the present embodiment provides a degradable stent 100, and the structure of the degradable stent 100 of the present embodiment is substantially the same as the structure of the degradable stent 100 of the first embodiment, except that: in the present embodiment, the closed contour 4 is in a shape of a right 8.

Example four

As shown in fig. 6: the present embodiment provides a degradable stent 100, and the structure of the degradable stent 100 of the present embodiment is substantially the same as the structure of the degradable stent 100 of the first embodiment, except that: closed profile 4 all is oblique 8 fonts in this embodiment, and all is provided with arc depressed part 14 at the inner wall of the corner of every closed profile 4, and arc depressed part 14 forms through excision processing, and the setting up of depressed part can increase the compliance and the deformation adaptability of support in the use of support

EXAMPLE five

As shown in fig. 7: the present embodiment provides a degradable stent 100, and the structure of the degradable stent 100 of the present embodiment is substantially the same as the structure of the degradable stent 100 of the first embodiment, except that: the first connecting rod 6, the second connecting rod 7, the third connecting rod 8 and the fourth connecting rod 9 in this embodiment all adopt straight rods.

In the description of the present invention, it should be noted that the terms "first" and "second" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.

The principle and the implementation mode of the present invention are explained by applying specific examples in the present specification, and the above descriptions of the examples are only used to help understanding the method and the core idea of the present invention; meanwhile, for a person skilled in the art, according to the idea of the present invention, the specific embodiments and the application range may be changed. In view of the above, the present disclosure should not be construed as limiting the invention.

Claims

1. A degradable stent, which is characterized in that: the device comprises a plurality of closed rings which are arranged at intervals along the axial direction, wherein the closed rings can be radially contracted and expanded, two adjacent closed rings are connected through a plurality of bridge rods which are uniformly arranged along the circumferential direction, and a plurality of through holes are uniformly arranged on the bridge rods along the axial direction; the closed ring and the bridge rod are made of polylactic acid, polylactic acid-glycolic acid copolymer, zinc, magnesium, iron, zinc alloy, magnesium alloy or degradable polymer.

2. The degradable stent of claim 1, wherein: the closed rings are uniformly arranged along the axial direction.

3. The degradable stent of claim 1, wherein: the closed ring comprises a plurality of combined units which are connected end to end, each combined unit comprises a plurality of connecting rods which are connected in sequence, and the two connected connecting rods are inclined relatively; the combined unit is in a curve shape; the combination units in two adjacent closed rings correspond to each other one by one, the joint of two adjacent combination units in the same closed ring is connected with one bridge rod, the two corresponding combination units are connected through the two bridge rods, and the two corresponding combination units and the two bridge rods between the two corresponding combination units form a closed contour.

4. The degradable stent of claim 3, wherein: a plurality of closed outlines in the same degradable stent are in a regular 8 shape, an oblique 8 shape, a rhombus-like shape or an S shape; the shape of the different said closed contours is the same or different.

5. The degradable stent of claim 3, wherein: the value range of the central angle occupied by the closed contour in the circumferential direction of the degradable stent is 10-120 degrees, and the number of the closed contour in the axial direction of the degradable stent ranges from 6 per centimeter to 12 per centimeter.

6. The degradable stent of claim 3, wherein: two adjacent connecting rods in one combined unit are also connected through an arc-shaped rod, and the two adjacent connecting rods and the arc-shaped rod form a rhombus-like closed structure; when the degradable stent is pressed and held, the arc-shaped rods can be inosculated with the corresponding connecting rods.

7. The degradable stent of claim 3, wherein: the inner wall at the corner of each closed contour is provided with an arc-shaped concave part, and the arc-shaped concave parts are formed through cutting treatment.

8. The degradable stent of claim 3, wherein: the connecting rods are all bent rods, and the protruding directions of the two adjacent connecting rods are opposite.

9. The degradable stent of claim 1, wherein: each bridge rod is provided with a plurality of developing marks.