CN113648109A - Transcatheter artificial mitral valve system - Google Patents
Transcatheter artificial mitral valve system Download PDFInfo
- Publication number
- CN113648109A CN113648109A CN202111005773.5A CN202111005773A CN113648109A CN 113648109 A CN113648109 A CN 113648109A CN 202111005773 A CN202111005773 A CN 202111005773A CN 113648109 A CN113648109 A CN 113648109A
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- China
- Prior art keywords
- assembly
- valve system
- mitral valve
- transcatheter
- prosthetic mitral
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
- A61F2/246—Devices for obstructing a leak through a native valve in a closed condition
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Prostheses (AREA)
Abstract
The invention belongs to the technical field of medical instruments, particularly relates to the field of A61F2/24, and particularly relates to a transcatheter artificial mitral valve system. The invention provides a transcatheter artificial mitral valve system, which comprises an artificial valve component, wherein the artificial valve component is arranged into a frame type structure with a ring diameter gradually expanded along the opposite direction of blood flow; the prosthetic valve assembly is bunched at the extreme distal end in the direction of blood flow; a pull assembly disposed at a distal end of the prosthetic valve assembly; an apex anchor assembly extending from outside the apex to the distraction assembly. Through setting up the haulage rope into the elastic cord, make the artificial valve subassembly under the traction of heart point anchor subassembly, can diminish and tighten up or lengthen along with the diastole grow of ventricle along with the ventricle shrink to can keep certain pulling force, the normal diastole of haulage rope cooperation ventricle does not influence the normal function of ventricle, reduces simultaneously and to heart muscle's dragging, avoids causing serious damage to the myocardium.
Description
Technical Field
The invention belongs to the technical field of medical instruments, particularly relates to the field of A61F2/24, and particularly relates to a transcatheter artificial mitral valve system.
Background
Surgery for heart valve disease is one of the most challenging operations in the field of structural heart disease, and the advent of transcatheter interventional therapy has rewrites the history of this field. The breakthrough of the technology from thoracotomy to minimally invasive intervention changes the heart valve into the gold-excavating hot soil while rewriting the history of disease treatment. Mitral Regurgitation (MR) is the most common valvular lesion in the western world, and european and american epidemiological research data show that the prevalence reaches 10% in people over 75 years of age, significantly exceeding aortic valvular lesions. It is estimated that the treatment rate of severe MR patients in China is more than 1500 ten thousand, but the treatment rate of surgical operation is lower than 2%. Study data showed that more than half of patients with severe mitral regurgitation have not selected surgical treatment due to the high risk of surgery. However, experts and doctors in the global industry pay more attention to treatment of mitral valve diseases, the mitral valve has greater risks and technical challenges due to structural characteristics (D shape + saddle shape), and at present, few people make breakthrough progress in the field of mitral valve treatment in China and even in the world. At present, the market treats the mature mode of the mitral valve, mainly adopts medicine and surgical operation, the rise of minimally invasive operation also brings hope for the treatment of the mitral valve, a batch of instruments mainly adopting intervention repair are clinically researched before the market or are already on the market, and the Chinese patent with the publication number of CN106236325B provides a conveyor and a conveying system of the artificial mitral valve forming ring. There is a need for a product that resembles a transcatheter aortic valve to replace/replace the native diseased valve, and mitral valve replacement is intended to replace the diseased native valve by implanting a prosthetic heart valve transapically/transfemonally, thereby permanently and effectively addressing the problem of mitral regurgitation. Replacement has wider indications than repair, the treatment is more thorough and effective, and the effect of the mitral valve disease which is replaced and cured by high-quality products is far more ideal than the repair.
There is only one transcatheter apical access mitral valve system approved by the european union, the Tendyne mitral valve system by Abbott corporation, on the market today. The product is implanted to the mitral valve position of a patient to replace a diseased mitral valve through a catheter through an apical approach, and the valve is connected to the outer wall of an apical ventricle through a traction rope and fixed at the apical position through an anchoring disc. To date, over 300 patients have implanted the Tendyne valve system, a product that greatly improves their quality of life.
The prior art valve system development, represented by the Tendyne valve system, has several problems: (1) the connecting rope used by the valve system and the heart apex reduces the distance from the heart apex to the valve ring plane when the heart ventricle contracts, the pulling rope becomes slack, the valve loses the tension in the heart apex direction for a short time, and the valve system is attached to the native valve ring structure, so that the valve periphery leakage is caused, and even the valve slides into the atrium for a short time; in the same way, in the diastole of the ventricle, the ventricle becomes large, the distance between the apex of the heart and the plane of the valve ring becomes large, the traction rope is pulled very tightly, the traction rope limits the normal relaxation of the ventricle to a certain extent at the moment to influence the normal cardiac function, and meanwhile, the traction rope also pulls the myocardium to a certain extent to bring damage. (2) The fixed point between the bracket and the connecting rope is positioned in the opening area of the valve leaflet, so that the opening area of the valve is reduced. (3) The valve to the valve ring is fixed at the apex of the heart by a connecting rope, so that the left ventricular outflow tract is easy to be blocked.
Disclosure of Invention
In view of the above problems, the present invention provides a transcatheter prosthetic mitral valve system comprising
A prosthetic valve assembly configured as a frame-like structure with a gradually expanding loop diameter in a direction opposite to blood flow; the prosthetic valve assembly is bunched at the extreme distal end in the direction of blood flow;
a pull assembly disposed at a distal end of the prosthetic valve assembly;
an apex anchor assembly extending from outside the apex to the distraction assembly.
As a preferred technical scheme, the traction assembly comprises a connecting seat and a connecting cap, the connecting cap is arranged at the far end of the connecting seat, and the connecting seat and the connecting cap are in matched connection through the internal thread of the connecting cap and the external thread of the connecting seat.
As a preferable technical solution, the connection holder includes a threaded portion and an end portion, the end portion is disposed at a proximal end of the threaded portion, and an outer diameter of the end portion is larger than an outer diameter of the threaded portion.
As an optimal technical scheme, grooves arranged along the flowing direction of blood are formed in the connecting seat, the number of the grooves is 3-8, the grooves are uniformly arranged along the outer ring of the connecting seat, and the grooves penetrate through the end portion and the threaded portion of the connecting seat.
As a preferred technical solution, the distal end of the artificial valve assembly is provided with a plurality of connecting feet, the connecting feet are arranged in parallel along the blood flowing direction, and the connecting feet are arranged in cooperation with the grooves.
As a preferred technical solution, the distal ends of several of the connecting legs are connected to each other by a circular ring.
As a preferred technical solution, the apical anchor assembly comprises a pulling rope and a gear mechanism, the gear mechanism is arranged outside the apical, and the pulling rope connects the pulling assembly and the gear mechanism; the hauling rope is an elastic rope.
As a preferred technical solution, the intracardiac anchor assembly further comprises an anchoring portion and a pulling portion, wherein the anchoring portion is used for fixing the intracardiac anchor assembly on the inner side wall of the myocardium, and the pulling rope passes through the pulling portion to change the pulling direction.
As a preferable technical scheme, the anchoring parts are arranged into a plurality of claw-shaped structures which turn outwards, the traction parts are arranged into a circular ring structure with a cross beam in the middle, and the anchoring parts are fixedly connected with the circular ring structure and uniformly distributed in the center of the circular ring structure; the cross beam is used for changing the traction direction of the traction rope.
As a preferred technical solution, the intracardiac anchor assembly is provided as a bent linear structure; the linear structure body is bent at the middle position to form a traction part, and two end parts of the linear structure body are outwards turned to form an anchoring part of a hook-shaped structure.
Has the advantages that: the invention provides a transcatheter artificial mitral valve system, which is used for solving the problem of difficult fixation of an artificial valve in the heart.
The invention provides a unique support structure, wherein a plurality of parallel connecting feet are arranged at the far end of a prosthetic valve component and used as a connecting structure of the prosthetic valve component and a traction component, and the connecting structure is arranged outside the opening area of valve leaflets and does not influence the opening area of the valve leaflets.
The present invention provides an intracardiac anchoring assembly in a transcatheter mitral valve system that reduces the risk of obstruction by adding an intracardiac myocardial fixation point, including an intracardiac muscle anchoring structure and delivery means, to limit the movement of the valve system in the direction/location of the left ventricular outflow tract.
Drawings
FIG. 1 is a schematic illustration of an application position of a transcatheter prosthetic mitral valve system provided by the present invention within a heart;
FIG. 2 is a schematic structural diagram of a transcatheter prosthetic mitral valve system provided in an embodiment;
FIG. 3 is a schematic structural view of a prosthetic valve assembly provided in the examples;
fig. 4 is a schematic structural diagram of a connection seat provided in the embodiment;
FIG. 5 is a schematic structural diagram of a transcatheter prosthetic mitral valve system provided in an embodiment;
FIG. 6 is a schematic diagram of the position of a transcatheter prosthetic mitral valve system in use inside the heart provided in the embodiments;
fig. 7 is a schematic view of the application position of an intracardiac anchor assembly within the heart provided in the example;
figure 8 is a schematic structural view of an intracardiac anchor assembly provided in the examples;
fig. 9 is a schematic view of the application position of an intracardiac anchor assembly within the heart provided in the example;
figure 10 is a schematic structural view of an intracardiac anchor assembly provided in the examples;
figure 11 is a schematic illustration of the delivery principle of an intracardiac anchor assembly provided in the examples;
figure 12 is a schematic illustration of the delivery principle of an intracardiac anchor assembly provided in the examples;
wherein, 1-artificial valve component, 11-connecting foot, 2-traction component, 21-connecting seat, 2101-screw thread part, 2102-end part, 2103-groove, 22-connecting cap, 3-apical anchoring component, 31-traction rope, 32-gear mechanism, 4-intracardiac anchoring component, 41-anchoring part and 42-traction part; 51-left atrium, 52-left ventricle, 53-ventricular wall structure, 6-delivery sheath.
Detailed Description
1-12, a transcatheter prosthetic mitral valve system comprising
The artificial valve component 1 is arranged into a frame type structure with the ring diameter gradually expanding along the opposite direction of blood flow; the prosthetic valve assembly 1 is bunched at the extreme distal end in the direction of blood flow;
a pulling assembly 2, the pulling assembly 2 being arranged at the distal end of the prosthetic valve assembly 1;
an apical anchor assembly 3, the apical anchor assembly 3 extending laterally from the apex of the heart to the traction assembly 2.
As shown in fig. 2, in some preferred embodiments, the pulling assembly 2 comprises a connecting seat 21 and a connecting cap 22, the connecting cap 22 is disposed at the distal end of the connecting seat 21, and the connecting seat 21 and the connecting cap 22 are connected by matching the internal thread of the connecting cap 22 and the external thread of the connecting seat 21.
In some preferred embodiments, the connecting socket 21 includes a threaded portion 2101 and an end 2102, the end 2102 is disposed at a proximal end of the threaded portion 2101, and an outer diameter of the end 2102 is larger than an outer diameter of the threaded portion 2101.
In some preferred embodiments, the connecting seat 21 is provided with grooves 2103 arranged along a blood flowing direction, the number of the grooves 2103 is 3-8, a plurality of the grooves 2103 are uniformly arranged along an outer ring of the connecting seat 21, and the grooves 2103 penetrate through the end 2102 and the threaded part 2101 of the connecting seat 21.
In some preferred embodiments, the valve prosthesis assembly 1 is provided with a plurality of connecting legs 11 at the distal end, the connecting legs 11 are arranged in parallel along the blood flowing direction, and the connecting legs 11 are arranged in cooperation with the grooves 2103.
Preferably, when the connecting pin is embedded into the groove, the diameter of the outer ring of the connecting pin is the same as the small diameter of the threaded portion, so that the installation of the connecting pin does not affect the matching connection between the connecting base and the connecting cap.
In some preferred embodiments, the distal ends of several of the connecting feet 11 are connected to each other by a circular ring. Annular limit pull rope and valve system separation
In some preferred embodiments, the apical anchor assembly 3 comprises a traction rope 31 and a shift mechanism 32, the shift mechanism 32 is disposed outside the apex of the heart, and the traction rope 31 connects the traction assembly 2 and the shift mechanism 32; the hauling rope 31 is arranged as an elastic rope.
Preferably, the hauling cable is made of super elastic material or elastic structure design, or a tubular braided fabric is coated on the outer layer of the material to enhance the strength of the hauling cable.
In some preferred embodiments, as shown in fig. 5, 6 or 3 connecting feet in the artificial valve component are gathered by leading along the perimeter edge of the support frame to a point on or outside the periphery of the valve, and are connected with a traction rope through a traction mechanism and fixed at the anchoring position of the apex of the heart, so that the purpose of not occupying the effective opening area of the valve is achieved.
In some preferred embodiments, further comprising an intracardiac anchor assembly 4, said intracardiac anchor assembly 4 comprising an anchoring portion 41 and a pulling portion 42, said anchoring portion 41 being adapted to secure said intracardiac anchor assembly 4 to the myocardial inner sidewall, said pull string 31 passing through said pulling portion 42 to change the direction of pulling.
As shown in fig. 7 and 8, in some preferred embodiments, the anchoring portions 41 are provided as a plurality of claw-shaped structures turned outwards, the pulling portions 42 are provided as a circular ring structure with a beam in the middle, and the anchoring portions 41 are fixedly connected with the circular ring structure and uniformly distributed in the center of the circular ring structure; the cross beam is used for changing the traction direction of the traction rope 31.
Fig. 11 is a schematic view showing the principle of delivery of the intracardiac anchor assembly, with the delivery sheath 6 withdrawn rearwardly to release the claws to penetrate the myocardium after reaching the target site.
In some preferred embodiments, the intracardiac anchor assembly 4 is provided as a bent linear structure, as shown in figures 9 and 10; the linear structure is bent at an intermediate position to form a pulling part 42, and both end parts 2102 of the linear structure are turned outwards to form anchoring parts 41 of a hook-type structure.
Fig. 12 is a schematic diagram showing the delivery principle of the intracardiac anchor assembly, wherein the anchoring portion 41 is a spring hook made of super elastic material, the pull string is passed through the circular hole of the tail structure, one end is connected to the valve system, the other end is connected to the apical fixation position, the delivery sheath 6 is pressed to the target position before implantation, then the spring hook is released, and the front end penetrates the myocardium and grabs the anchor firmly.
The working principle is as follows: the invention provides a transcatheter artificial mitral valve system, wherein an artificial valve component 1 is arranged in an annulus between a left atrium 51 and a left ventricle 52, a diseased native valve is replaced by the artificial valve, one end of the artificial valve system extending into the left atrium has a fixing function through a structure of gradually expanding the ring diameter, the artificial valve system is prevented from falling off towards the left ventricle under the driving of blood flow, and meanwhile, a cardiac apex anchor component is arranged, so that the artificial valve component is prevented from being extruded out and falling off towards the left atrium when the ventricle expands through the drawing action of a traction rope. The far end of the artificial valve component is provided with a plurality of parallel connecting feet which are used as the connecting structure of the artificial valve component and the traction component, and the connecting structure is arranged outside the opening area of the valve leaflet and does not influence the opening area of the valve leaflet. The present invention provides an intracardiac anchoring assembly in a transcatheter mitral valve system that reduces the risk of obstruction by adding an intracardiac myocardial fixation point, including an intracardiac muscle anchoring structure and delivery means, to limit the movement of the valve system in the direction/location of the left ventricular outflow tract.
Claims (10)
1. A transcatheter prosthetic mitral valve system, comprising
The artificial valve component (1), the artificial valve component (1) is arranged into a frame type structure with the ring diameter gradually expanding along the opposite direction of blood flow; the prosthetic valve assembly (1) is bunched at the extreme end along the blood flow direction;
a pulling assembly (2), the pulling assembly (2) being disposed at a distal end of the prosthetic valve assembly (1);
an apical anchor assembly (3), the apical anchor assembly (3) extending laterally from the apex to the distraction assembly (2).
2. The transcatheter prosthetic mitral valve system according to claim 1, wherein the pulling assembly (2) comprises a connecting hub (21) and a connecting cap (22), the connecting cap (22) being disposed at a distal end of the connecting hub (21), the connecting hub (21) and the connecting cap (22) being cooperatively connected by an internal thread of the connecting cap (22) and an external thread of the connecting hub (21).
3. The transcatheter prosthetic mitral valve system of claim 2, wherein the attachment hub (21) comprises a threaded portion (2101) and an end portion (2102), the end portion (2102) being disposed proximal to the threaded portion (2101), the end portion (2102) having an outer diameter that is greater than an outer diameter of the threaded portion (2101).
4. The transcatheter prosthetic mitral valve system according to claim 3, wherein the connection seat (21) is provided with grooves (2103) arranged along a blood flow direction, the number of the grooves (2103) is 3-8, a plurality of the grooves (2103) are uniformly arranged along an outer ring of the connection seat (21), and the grooves (2103) are arranged through the end portion (2102) and the threaded portion (2101) of the connection seat (21).
5. The transcatheter prosthetic mitral valve system according to claim 4, wherein the prosthetic valve assembly (1) is provided at a distal end with a plurality of connection feet (11), wherein the plurality of connection feet (11) are arranged in parallel in a blood flow direction, and wherein the connection feet (11) are arranged in cooperation with the grooves (2103).
6. The transcatheter prosthetic mitral valve system according to claim 5, wherein the distal ends of several of the connecting feet (11) are connected to each other by a circular ring.
7. The transcatheter prosthetic mitral valve system according to claim 5, wherein the apex anchor assembly (3) comprises a pull cord (31) and a shift mechanism (32), the shift mechanism (32) being disposed outside the apex of the heart, the pull cord (31) connecting the pull assembly (2) and the shift mechanism (32); the traction rope (31) is an elastic rope.
8. The transcatheter prosthetic mitral valve system of claim 5, further comprising an intracardiac anchor assembly (4), the intracardiac anchor assembly (4) comprising an anchoring portion (41) and a pulling portion (42), the anchoring portion (41) for securing the intracardiac anchor assembly (4) to a myocardial inner sidewall, the pull cord (31) passing through the pulling portion (42) changing a pulling direction.
9. The transcatheter prosthetic mitral valve system according to claim 8, wherein the anchoring portions (41) are provided as a plurality of claw-shaped structures turned toward the outside, the traction portions (42) are provided as a circular ring structure with a beam in the middle, and the anchoring portions (41) are fixedly connected with the circular ring structure and uniformly distributed in the center of the circular ring structure; the cross beam is used for changing the traction direction of the traction rope (31).
10. The transcatheter prosthetic mitral valve system of claim 8, wherein the intracardiac anchor assembly (4) is provided as one bent linear structure; the linear structure is bent at the middle position to form a traction part (42), and two end parts (2102) of the linear structure are outwards turned to form an anchoring part (41) of a hook-shaped structure.
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CN202111005773.5A CN113648109B (en) | 2021-08-30 | 2021-08-30 | Transcatheter artificial mitral valve system |
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CN202111005773.5A CN113648109B (en) | 2021-08-30 | 2021-08-30 | Transcatheter artificial mitral valve system |
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CN113648109B CN113648109B (en) | 2023-08-25 |
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US20150223934A1 (en) * | 2014-02-11 | 2015-08-13 | Tendyne Holdings, Inc. | Adjustable tether and epicardial pad system for prosthetic heart valve |
CN109925095A (en) * | 2017-12-18 | 2019-06-25 | 先健科技(深圳)有限公司 | Heart valve |
US20190343634A1 (en) * | 2018-05-09 | 2019-11-14 | Neochord, Inc. | Radial arm tissue anchor for minimally invasive heart valve repair |
CN110934664A (en) * | 2018-09-25 | 2020-03-31 | 先健科技(深圳)有限公司 | Heart valve |
US20210030537A1 (en) * | 2019-07-31 | 2021-02-04 | Tendyne Holdings, Inc. | Tethering System For A Prosthetic Heart Valve |
CN212522083U (en) * | 2019-12-19 | 2021-02-12 | 先健科技(深圳)有限公司 | Heart valve |
CN213156729U (en) * | 2020-06-01 | 2021-05-11 | 宁波健世生物科技有限公司 | Novel valve prosthesis with adjustable fixing end |
-
2021
- 2021-08-30 CN CN202111005773.5A patent/CN113648109B/en active Active
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20150223934A1 (en) * | 2014-02-11 | 2015-08-13 | Tendyne Holdings, Inc. | Adjustable tether and epicardial pad system for prosthetic heart valve |
CN109925095A (en) * | 2017-12-18 | 2019-06-25 | 先健科技(深圳)有限公司 | Heart valve |
US20190343634A1 (en) * | 2018-05-09 | 2019-11-14 | Neochord, Inc. | Radial arm tissue anchor for minimally invasive heart valve repair |
CN110934664A (en) * | 2018-09-25 | 2020-03-31 | 先健科技(深圳)有限公司 | Heart valve |
US20210030537A1 (en) * | 2019-07-31 | 2021-02-04 | Tendyne Holdings, Inc. | Tethering System For A Prosthetic Heart Valve |
CN212522083U (en) * | 2019-12-19 | 2021-02-12 | 先健科技(深圳)有限公司 | Heart valve |
CN213156729U (en) * | 2020-06-01 | 2021-05-11 | 宁波健世生物科技有限公司 | Novel valve prosthesis with adjustable fixing end |
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