CN113520720B - Closed negative pressure drainage dressing system - Google Patents
Closed negative pressure drainage dressing system Download PDFInfo
- Publication number
- CN113520720B CN113520720B CN202110798589.4A CN202110798589A CN113520720B CN 113520720 B CN113520720 B CN 113520720B CN 202110798589 A CN202110798589 A CN 202110798589A CN 113520720 B CN113520720 B CN 113520720B
- Authority
- CN
- China
- Prior art keywords
- negative pressure
- dressing
- oil
- dimensional mesh
- ointment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000002674 ointment Substances 0.000 claims abstract description 60
- 239000005871 repellent Substances 0.000 claims abstract description 37
- 239000004744 fabric Substances 0.000 claims abstract description 36
- 238000007789 sealing Methods 0.000 claims abstract description 24
- 230000000844 anti-bacterial effect Effects 0.000 claims abstract description 23
- 230000000840 anti-viral effect Effects 0.000 claims abstract description 12
- 230000003014 reinforcing effect Effects 0.000 claims abstract description 11
- 239000000835 fiber Substances 0.000 claims abstract description 7
- 241000196324 Embryophyta Species 0.000 claims description 38
- 239000011248 coating agent Substances 0.000 claims description 27
- 238000000576 coating method Methods 0.000 claims description 27
- WHBMMWSBFZVSSR-UHFFFAOYSA-N R3HBA Natural products CC(O)CC(O)=O WHBMMWSBFZVSSR-UHFFFAOYSA-N 0.000 claims description 20
- 150000001875 compounds Chemical class 0.000 claims description 7
- 239000003921 oil Substances 0.000 claims description 5
- 235000019198 oils Nutrition 0.000 claims description 5
- 238000006116 polymerization reaction Methods 0.000 claims description 5
- 235000015112 vegetable and seed oil Nutrition 0.000 claims description 4
- 239000008158 vegetable oil Substances 0.000 claims description 4
- 229920001577 copolymer Polymers 0.000 claims description 3
- 239000002121 nanofiber Substances 0.000 claims description 3
- 239000011148 porous material Substances 0.000 claims description 3
- 230000001502 supplementing effect Effects 0.000 claims description 3
- 229920001661 Chitosan Polymers 0.000 claims description 2
- 108010022355 Fibroins Proteins 0.000 claims description 2
- 235000019483 Peanut oil Nutrition 0.000 claims description 2
- 239000004372 Polyvinyl alcohol Substances 0.000 claims description 2
- 235000013871 bee wax Nutrition 0.000 claims description 2
- 239000012166 beeswax Substances 0.000 claims description 2
- 239000010495 camellia oil Substances 0.000 claims description 2
- 239000004359 castor oil Substances 0.000 claims description 2
- 235000019438 castor oil Nutrition 0.000 claims description 2
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 claims description 2
- 239000000463 material Substances 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims description 2
- 239000004006 olive oil Substances 0.000 claims description 2
- 235000008390 olive oil Nutrition 0.000 claims description 2
- 239000000312 peanut oil Substances 0.000 claims description 2
- 239000010773 plant oil Substances 0.000 claims description 2
- 229920002635 polyurethane Polymers 0.000 claims description 2
- 239000004814 polyurethane Substances 0.000 claims description 2
- 229920002451 polyvinyl alcohol Polymers 0.000 claims description 2
- 238000000197 pyrolysis Methods 0.000 claims description 2
- 239000008159 sesame oil Substances 0.000 claims description 2
- 235000011803 sesame oil Nutrition 0.000 claims description 2
- 235000020238 sunflower seed Nutrition 0.000 claims description 2
- WHBMMWSBFZVSSR-UHFFFAOYSA-M 3-hydroxybutyrate Chemical group CC(O)CC([O-])=O WHBMMWSBFZVSSR-UHFFFAOYSA-M 0.000 claims 2
- SJZRECIVHVDYJC-UHFFFAOYSA-M 4-hydroxybutyrate Chemical compound OCCCC([O-])=O SJZRECIVHVDYJC-UHFFFAOYSA-M 0.000 claims 1
- UQGPCEVQKLOLLM-UHFFFAOYSA-N pentaneperoxoic acid Chemical compound CCCCC(=O)OO UQGPCEVQKLOLLM-UHFFFAOYSA-N 0.000 claims 1
- 210000000605 viral structure Anatomy 0.000 claims 1
- 235000015097 nutrients Nutrition 0.000 abstract description 3
- 230000002349 favourable effect Effects 0.000 abstract 1
- 206010052428 Wound Diseases 0.000 description 37
- 208000027418 Wounds and injury Diseases 0.000 description 36
- 238000000034 method Methods 0.000 description 9
- 230000008569 process Effects 0.000 description 7
- 238000012377 drug delivery Methods 0.000 description 6
- 238000005516 engineering process Methods 0.000 description 6
- 230000035876 healing Effects 0.000 description 6
- 239000000126 substance Substances 0.000 description 6
- 230000002829 reductive effect Effects 0.000 description 5
- 238000009958 sewing Methods 0.000 description 5
- 241000222122 Candida albicans Species 0.000 description 4
- 241000588724 Escherichia coli Species 0.000 description 4
- 241000191967 Staphylococcus aureus Species 0.000 description 4
- 229940095731 candida albicans Drugs 0.000 description 4
- 230000008859 change Effects 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 239000012528 membrane Substances 0.000 description 4
- 239000002994 raw material Substances 0.000 description 4
- 208000035143 Bacterial infection Diseases 0.000 description 3
- 230000001580 bacterial effect Effects 0.000 description 3
- 208000022362 bacterial infectious disease Diseases 0.000 description 3
- 239000002131 composite material Substances 0.000 description 3
- 238000005520 cutting process Methods 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 230000002980 postoperative effect Effects 0.000 description 3
- 238000004080 punching Methods 0.000 description 3
- 230000009385 viral infection Effects 0.000 description 3
- JRHWHSJDIILJAT-UHFFFAOYSA-N 2-hydroxypentanoic acid Chemical compound CCCC(O)C(O)=O JRHWHSJDIILJAT-UHFFFAOYSA-N 0.000 description 2
- SJZRECIVHVDYJC-UHFFFAOYSA-N 4-hydroxybutyric acid Chemical compound OCCCC(O)=O SJZRECIVHVDYJC-UHFFFAOYSA-N 0.000 description 2
- 208000008960 Diabetic foot Diseases 0.000 description 2
- 208000036142 Viral infection Diseases 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 239000003242 anti bacterial agent Substances 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 238000000855 fermentation Methods 0.000 description 2
- 230000004151 fermentation Effects 0.000 description 2
- 230000005660 hydrophilic surface Effects 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 230000001338 necrotic effect Effects 0.000 description 2
- 230000035699 permeability Effects 0.000 description 2
- 229920000520 poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Polymers 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- 230000029663 wound healing Effects 0.000 description 2
- 241000228245 Aspergillus niger Species 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 229920002261 Corn starch Polymers 0.000 description 1
- 241000701022 Cytomegalovirus Species 0.000 description 1
- 206010011985 Decubitus ulcer Diseases 0.000 description 1
- 208000007514 Herpes zoster Diseases 0.000 description 1
- 241000701085 Human alphaherpesvirus 3 Species 0.000 description 1
- 239000004900 Hydrophilic Finishing Agent Substances 0.000 description 1
- 241000712431 Influenza A virus Species 0.000 description 1
- 241001484259 Lacuna Species 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 206010031252 Osteomyelitis Diseases 0.000 description 1
- 208000004210 Pressure Ulcer Diseases 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- 208000026137 Soft tissue injury Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 238000004026 adhesive bonding Methods 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 230000036760 body temperature Effects 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 239000008120 corn starch Substances 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 239000007857 degradation product Substances 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 230000002888 effect on disease Effects 0.000 description 1
- 230000003628 erosive effect Effects 0.000 description 1
- 230000032050 esterification Effects 0.000 description 1
- 238000005886 esterification reaction Methods 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 238000013012 foaming technology Methods 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 230000002147 killing effect Effects 0.000 description 1
- 238000011031 large-scale manufacturing process Methods 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 230000036961 partial effect Effects 0.000 description 1
- 239000012466 permeate Substances 0.000 description 1
- 238000000554 physical therapy Methods 0.000 description 1
- 239000002861 polymer material Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000002940 repellent Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 238000011179 visual inspection Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Images
Classifications
-
- A61F13/01008—
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/00051—Accessories for dressings
- A61F13/00063—Accessories for dressings comprising medicaments or additives, e.g. odor control, PH control, debriding, antimicrobic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/00987—Apparatus or processes for manufacturing non-adhesive dressings or bandages
- A61F13/00991—Apparatus or processes for manufacturing non-adhesive dressings or bandages for treating webs, e.g. for moisturising, coating, impregnating or applying powder
-
- A61F13/01029—
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive plasters or dressings
- A61F13/0203—Adhesive plasters or dressings having a fluid handling member
- A61F13/0226—Adhesive plasters or dressings having a fluid handling member characterised by the support layer
-
- A61F13/05—
Abstract
The invention discloses a closed negative pressure drainage dressing system, which consists of three-dimensional mesh cloth containing antibacterial and antiviral components, plant ointment, an administration tube, a hydrophilic and oil-repellent covering film, a mesopore reinforcing ring, porous dressing, a sealing film and an attached sucker from inside to outside; the dressing three-dimensional mesh fabric layer is prepared by adding fibers into antibacterial and antiviral components, so that the dressing provides nutrient components for a wound surface and prevents the wound surface from being infected, the three-dimensional mesh fabric is favorable for drainage of seepage and storage of ointment, long-time continuous provision of nutrient components is guaranteed, and the hydrophilic and oil-repellent covering film prevents the plant ointment from being sucked away when continuous negative pressure drainage is provided, so that quick drainage is realized, and wound seepage is prevented.
Description
Technical Field
The invention belongs to the technical field of medical instruments, and particularly relates to a closed negative pressure drainage dressing system.
Background
VSD negative pressure drainage is a novel method for treating superficial wounds and for deep drainage. Can thoroughly remove the secretion and necrotic tissues of lacuna or wound surfaces, has good treatment effect on diseases such as osteomyelitis and the like which are difficult to treat internally, and is an innovation of surgical treatment technology. The technology utilizes a biological semi-permeable membrane to seal an open wound surface, is matched with high-plasticity medical foam to be filled to form a shape matched with the wound surface, and fully drains wound surface seepage and necrotic tissues through a drainage tube by means of negative pressure, thereby relieving edema, reducing wound surface pollution, inhibiting bacterial growth, promoting wound surface healing and achieving the purpose of treatment. Meanwhile, frequent dressing change in the traditional process of treating the open severe soft tissue injury wound is avoided, the pain of a patient is relieved, and the working intensity of medical staff is reduced. Currently, the VSD negative pressure drainage technology is widely applied to clinic and is a simple, efficient and economic pure physical therapy for promoting wound healing. But the wound surface can not be completely sealed by using the side cannula design, and the conditions of air leakage and insufficient negative pressure value can also occur.
The drainage device disclosed by Chinese patent with patent number ZL201320578406.9 and name of 'double-hole type suction cup negative pressure drainage device' comprises the following structure: the wound dressing comprises a porous wound dressing covered on a wound, a biological semipermeable membrane used for sealing the porous wound dressing on the surface of a human body, a sucking disc attached to the biological semipermeable membrane and covering the wound, a mouth drainage device connected to the sucking disc and a flushing device. The suction disc is added in the drainage device, so that the negative pressure distribution on the whole negative pressure dressing is more uniform. However, the following problems are still found in the use process: firstly, when the negative pressure dressing is replaced, the condition that the newborn granulation is interacted with the negative pressure dressing exists, so that the pain of secondary damage during replacement is caused; secondly, in order to clean the wound surface, a pipeline is arranged in the negative pressure dressing, and when negative pressure suction is carried out, if improper operation or limited bearing capacity of a patient is carried out, pressure sores can be caused on the wound surface.
The patent number is 202011427073.0, and the name is a wound surface negative pressure drainage dressing with long-acting antibacterial activity and a structure thereof. The utility model provides a wound surface negative pressure drainage dressing with long-term antibacterial activity and structure thereof, the wound surface negative pressure drainage dressing with long-term antibacterial activity includes: the negative pressure drainage dressing comprises an antibacterial substance and a negative pressure dressing raw material, wherein the antibacterial substance is a zinc-containing high polymer material and can emit electromagnetic waves, the electromagnetic waves can destroy DNA and cell membranes of bacteria, the antibacterial substance is added into the negative pressure dressing raw material, the antibacterial substance and the negative pressure dressing raw material are mixed and then prepared into the negative pressure drainage dressing by a foaming technology, the mass fraction of the antibacterial substance in the total negative pressure drainage dressing is 0.02-2%, and the negative pressure drainage dressing has long-acting antibacterial capacity and can form long-acting physical antibacterial action on a wound surface. However, the following problems exist in the using process: the drainage speed is slow, and the wound is easy to seep liquid.
Disclosure of Invention
The invention mainly provides a closed negative pressure drainage dressing system which is used for solving the technical problems in the background technology.
The invention solves the technical problems and adopts the technical scheme that:
a closed negative pressure drainage dressing system comprises three-dimensional mesh containing antibacterial and antiviral components, vegetable ointment, administration tube, hydrophilic and oil-repellent coating, mesopore reinforcing ring, porous dressing, sealing film, and attached sucking disc from inside to outside; wherein, the administration tube is used for continuously supplementing the plant ointment; the full-layer pore diameter of the hydrophilic oil-repellent coating film quickly drains seepage to a porous dressing layer and prevents the plant ointment from being sucked away by closed negative pressure; the upper layer of the three-dimensional mesh cloth, the hydrophilic oil-repellent covering film and the porous dressing are provided with through holes to form a channel, the administration tube is arranged in the three-dimensional mesh cloth through one end of the channel and used for continuously administering the plant ointment and dispersing the plant ointment in the three-dimensional mesh cloth, the other end of the administration tube extends out of the attached sucker to be connected with the outer side of the three-dimensional mesh cloth and continuously administering the plant ointment to the plant, and the administration tube is fixed at the through hole of the hydrophilic oil-repellent covering film by adopting a middle hole reinforcing ring and is prevented from being sucked away from the gap of the through holes; the sealing film is applied to the outer layer of the porous dressing to form a sealing system, and the sealing film is opened at the through hole of the porous dressing and is further sealed by the attaching sucker; the porous dressing has a porous hole communicating structure to form a full-layer drainage channel; the attached sucker is communicated with a negative pressure source through a conduit to form a drainage channel, and meanwhile, an administration tube arranged in the conduit extends out of the outer side to be connected with an ointment supply device.
Preferably, the thickness ratio of the three-dimensional mesh cloth, the hydrophilic oil-repellent coating film and the porous dressing is 1 (0.01-0.05) to 10-30.
Preferably, the three-dimensional mesh fabric is prepared from antibacterial and antiviral component compound fibers, has certain rigidity strength and a stereoscopic skeleton structure, and is used for supporting negative pressure.
Preferably, the plant ointment is filled in a three-dimensional mesh. For the wound surface needing ointment treatment, particularly the burn wound surface, a corresponding device does not exist at present, if the sponge dressing of the existing device is directly used for contact, the plant ointment which can continuously provide nutrient substances for the wound surface cannot be guaranteed, and meanwhile, the ointment cannot be adsorbed out under the negative pressure condition.
Preferably, the plant ointment is prepared from pure plant oil or medicinal extract oil and beeswax, and the prepared plant ointment has a honeycomb frame structure.
Preferably, the pure vegetable oil is one or a mixture of more of sesame oil, castor oil, olive oil, sunflower seed oil, peanut oil and tea oil. Due to the weak acid characteristics of vegetable oil, the weak acid environment of skin and mucosa can be maintained; the liquid can be subjected to enzymolysis, hydrolysis and esterification with wound surface to promote liquefaction of wound surface. The frame dosage form ointment can intelligently release the vegetable oil according to the body temperature and the wound surface condition, and achieves better and continuous curative effect. Has antibacterial and antiinflammatory effects, and is convenient for use.
Preferably, the hydrophilic oil-repellent coating is made of nanofiber materials, the nanofibers are specifically interwoven, seepage liquid with good fluidity can seep out, semisolid ointment cannot permeate through the coating, and the coating has good air permeability.
Preferably, the hydrophilic oil-repellent coating is subjected to a hydrophilic oil-repellent treatment. The hydrophilic and oil repellent treatment process is a common technical means, and is a finishing technological process for treating a fabric by using a hydrophilic finishing agent to form a hydrophilic surface on a fiber. The finished fabric has a relatively high hydrophilic surface tension, which allows water to rapidly penetrate into the fabric on the fabric, thereby producing a hydrophilic effect.
Preferably, the porous dressing is polyurethane or polyvinyl alcohol sponge or chitosan sponge or silk fibroin sponge.
Preferably, the antibacterial and antiviral component is 3-hydroxybutyric acid oligomer, the degree of polymerization is 2-30, and the 3-hydroxybutyric acid oligomer is prepared by high-temperature pyrolysis of a copolymer of hydroxybutyric acid and hydroxyvaleric acid. The copolymer of hydroxybutyric acid and hydroxyvaleric acid (PHBV) is prepared by using corn starch as raw material and utilizing microbial fermentation engineering technology to realize large-scale production. PHBV is thermally degraded during high-temperature processing, and the main degradation product is 3-hydroxybutyric acid oligomer (OPHB for short). Research shows that OPHB has excellent antibacterial and antiviral properties. The inhibition rate of the compound preparation on microorganisms such as escherichia coli, staphylococcus aureus, candida albicans, pseudomonas aeruginosa, aspergillus niger and the like is over 90 percent. The antiviral structure shows that the fire extinguishing rate of the compound to influenza A virus reaches 99.99 percent.
The three-dimensional mesh, the hydrophilic oil-repellent coating and the porous dressing are spliced by ultrasonic sewing.
Compared with the prior art, the invention has the beneficial effects that:
(1) in addition to common bacterial infections, there are also wound viral infections, now found with varicella zoster virus and cytomegalovirus. It is mainly seen in the II degree burn wound or healed wound and donor area. Blisters and shingles were visible by visual inspection, and erosion occurred with secondary bacterial infection. The components contained in the plant ointment are compounded with an antiviral biomaterial, so that the healing of wound surface bacterial or viral infection can be accelerated.
(2) When the closed negative pressure drainage dressing system is used for treating wounds, the dressing can be replaced once in 3-10 days, and the closed negative pressure drainage dressing system has the characteristics of quick wound healing, low infection rate, less dressing replacement times, less antibacterial medicament use, reduction of medical cost and the like, can accelerate the healing time of acute wounds by over 60 percent, accelerate the healing speed of chronic wounds by 2-3 times, and reduce the medical cost.
(3) The antibacterial and antiviral components prepared by biological fermentation are natural, environment-friendly, efficient, few in side effect, high in bacterial and virus killing rate and capable of effectively preventing partial virus infection.
(4) The three-dimensional mesh cloth prepared by adopting a specific process has a three-dimensional skeleton structure, has a certain supporting force under a negative pressure state, has enough space for storing the plant ointment, can reduce the administration times, is simple to operate, is breathable, and supplies sufficient oxygen to the wound surface (the plant ointment is the medicine for changing the wound).
(5) The nano-scale hydrophilic oil-repellent coating can quickly drain seepage and prevent the ointment from being sucked out by negative pressure, thereby ensuring the curative effect.
(6) The three-dimensional mesh, the hydrophilic oil-repellent coating and the porous dressing are spliced by ultrasonic sewing. The technology is integrated into one piece for bonding, repeated process repetition caused by gluing is reduced, the air permeability of the dressing is influenced, and the three-dimensional mesh cloth is prevented from being cut and chipped.
(7) By using the closed negative pressure drainage dressing system, a large amount of ointment does not need to be smeared in 5-9 d after operation, and the ointment is automatically sucked in a negative pressure environment, so that the burden of medical workers is greatly reduced, and the smell of a ward is reduced.
Drawings
FIG. 1 is a schematic view of the structure of the present invention.
Fig. 2 is a schematic view of the structure of the administration tube of the present invention.
In the figure: 1, three-dimensional mesh cloth; 2, plant ointment; 3, an administration tube; 4, coating a hydrophilic oil-repellent film; 5, attaching a sucker; 6, a catheter; 7, a porous dressing; 8, a middle hole reinforcing ring; and 9, sealing the membrane.
Detailed Description
In order to facilitate an understanding of the invention, the invention will now be described more fully hereinafter with reference to the accompanying drawings, in which several embodiments of the invention are shown, but which may be embodied in different forms and not limited to the embodiments described herein, but which are provided so as to provide a more thorough and complete disclosure of the invention.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs, and the knowledge of the terms used herein in the specification of the present invention is for the purpose of describing particular embodiments and is not intended to limit the present invention, and the term "and/or" as used herein includes any and all combinations of one or more of the associated listed items.
A closed negative pressure drainage dressing system comprises three-dimensional mesh cloth 1 containing antibacterial and antiviral components, plant ointment 2, an administration tube 3, a hydrophilic and oil-repellent coating film 4, a mesopore reinforcing ring 8, a porous dressing 7, a sealing film 9 and an attached sucker 5 from inside to outside; wherein, the administration tube 3 is used for continuously supplementing the plant ointment 2; the whole-layer pore diameter of the hydrophilic oil-repellent coating 4 quickly drains seepage to the 7 layers of porous dressing and prevents the plant ointment 2 from being sucked away by closed negative pressure; the upper layer of the three-dimensional mesh cloth 1, the hydrophilic oil-repellent covering film 4 and the porous dressing 7 are provided with through holes to form a channel, one end of the administration tube 3 is arranged in the three-dimensional mesh cloth 1 through the channel and used for continuously administering the plant ointment 2 and dispersing the plant ointment in the channel, the other end of the administration tube extends out of the attached sucker 5 to be connected with the outer side of the plant ointment 2, and the through hole of the hydrophilic oil-repellent covering film 4 is fixed with the administration tube 3 by adopting a middle hole reinforcing ring 8 and prevents the plant ointment 2 from being sucked away from the gap of the through hole; the sealing film 9 is pasted on the outer layer of the porous dressing 7 to form a sealing system, and the sealing film 9 is opened at the through hole of the porous dressing 7 and is further sealed by the pasting sucker 5; the porous dressing 7 has a porous hole communicating structure to form a full-layer drainage channel; the attached sucker 5 is communicated with a negative pressure source through a conduit 6 to form a drainage channel, and meanwhile, the administration tube 3 arranged in the conduit 6 extends out of the outer side to be connected with a plant ointment supply device.
Example 1
3-hydroxybutyric acid oligomer with the polymerization degree of 5 is adopted to compound fibers to obtain 2mm three-dimensional mesh cloth, wherein the content of the 3-hydroxybutyric acid oligomer is 5%. Placing the three-dimensional mesh, the hydrophilic oil-repellent coated film and the porous dressing from bottom to top in sequence, and punching holes at specific positions to form an ointment supply channel; the method comprises the following steps of adhering a middle hole reinforcing ring at the through hole of a hydrophilic oil-repellent coating (preventing plant ointment filled in a three-dimensional mesh structure from being absorbed by negative pressure through gaps of the through holes of the coating), aligning the three-dimensional mesh, the hydrophilic oil-repellent coating and the perforated dressing, sewing and cutting by ultrasonic waves to obtain 10cm x 10cm composite dressing, placing the obtained dressing at an affected part, pasting a sealing film, opening the upper part of the sealing film, inserting one end of an administration tube into a three-dimensional mesh layer through an ointment supply channel, inserting the other end of the administration tube into an attached sucker, extending out the administration tube through a catheter to be connected with an ointment supply device, adhering the attached sucker to the sealing film, and connecting the sucker with a negative pressure source through the catheter. When in use, the negative pressure source is turned on, 10g of the plant ointment is automatically inhaled under the negative pressure through the administration tube, the negative pressure is kept, and 10g of the ointment is administered at intervals of 3 hours. Through using this sealed negative pressure drainage dressing system, need not change dressings in the postoperative 5 ~ 9d, alleviateed medical personnel's burden greatly, also reduced the misery of patient when dismantling traditional packing. Reduces the infection probability of the wound surface, and has bacteriostasis rate of more than 60 percent on escherichia coli, staphylococcus aureus and candida albicans.
Example 2
3-hydroxybutyric acid oligomer with the polymerization degree of 5 is adopted to compound fibers to obtain 2mm three-dimensional mesh cloth, wherein the content of the 3-hydroxybutyric acid oligomer is 7%. Placing the three-dimensional mesh, the hydrophilic oil-repellent coated film and the porous dressing from bottom to top in sequence, and punching holes at specific positions to form an ointment supply channel; adhering a mesopore reinforcing ring at the through hole of the hydrophilic oil-repellent coating film (preventing the plant ointment filled in the three-dimensional mesh fabric structure from being adsorbed out by negative pressure through the gap of the coating film through hole), aligning the three-dimensional mesh fabric, the hydrophilic oil-repellent coating film and the perforated part of the porous dressing, sewing and cutting by ultrasonic waves to obtain 10cm x 10cm composite dressing, placing the obtained dressing on an affected part, pasting a sealing film, opening the upper part of the sealing film, inserting one end of a drug delivery tube into the three-dimensional mesh fabric layer through an ointment supply channel, inserting the other end of the drug delivery tube into an attached sucker, stretching out the drug delivery tube through a catheter and connecting an ointment supply device, adhering the attached sucker to the sealing film, and connecting the sucker with a negative pressure source through the catheter. When in use, the negative pressure source is turned on, 20g of plant ointment is automatically inhaled under the negative pressure of the administration tube, the negative pressure is kept, and 20g of ointment is administered at an interval of 3 hours. Through using this closed negative pressure drainage dressing system, need not change dressings in the postoperative 5 ~ 9 d. The bacteriostasis rate of the antibacterial agent to escherichia coli, staphylococcus aureus and candida albicans is more than 80 percent. 30 cases of the 3-grade diabetic foot are selected, and the average healing time is shortened by 3-5 days compared with that of the case 1.
Example 3
3-hydroxybutyric acid oligomer with the polymerization degree of 5 is adopted to compound fibers to obtain 3mm three-dimensional mesh cloth, wherein the content of the 3-hydroxybutyric acid oligomer is 10%. Placing the three-dimensional mesh, the hydrophilic oil-repellent coated film and the porous dressing from bottom to top in sequence, and punching holes at specific positions to form an ointment supply channel; adhering a mesopore reinforcing ring at the through hole of the hydrophilic oil-repellent coating film (preventing the plant ointment filled in the three-dimensional mesh fabric structure from being adsorbed out by negative pressure through the gap of the coating film through hole), aligning the three-dimensional mesh fabric, the hydrophilic oil-repellent coating film and the perforated part of the porous dressing, sewing and cutting by ultrasonic waves to obtain 10cm x 10cm composite dressing, placing the obtained dressing on an affected part, pasting a sealing film, opening the upper part of the sealing film, inserting one end of a drug delivery tube into the three-dimensional mesh fabric layer through an ointment supply channel, inserting the other end of the drug delivery tube into an attached sucker, stretching out the drug delivery tube through a catheter and connecting an ointment supply device, adhering the attached sucker to the sealing film, and connecting the sucker with a negative pressure source through the catheter. When in use, the negative pressure source is turned on, 25g of plant ointment is automatically inhaled under the negative pressure of the administration tube, the negative pressure is kept, and 25g of ointment is administered at an interval of 4 hours. Through using this closed negative pressure drainage dressing system, need not change dressings in the postoperative 5 ~ 9 d. The bacteriostasis rate of the antibacterial agent to escherichia coli, staphylococcus aureus and candida albicans is greater than 85%. 30 diabetic foot cases of grade 3 are selected, the average healing time is shortened by 3-5 days compared with that of example 1, and the difference with example 2 is not obvious.
Claims (7)
1. A closed negative pressure drainage dressing system is characterized in that the dressing consists of a three-dimensional mesh containing antibacterial and antiviral components, a plant ointment, an administration tube, a hydrophilic oil-repellent coating, a mesopore reinforcing ring, a porous dressing, a sealing film and an attached sucker from inside to outside; wherein the administration tube is used for continuously supplementing the plant ointment; the full-layer pore diameter of the hydrophilic oil-repellent coating film quickly drains seepage to a porous dressing layer and prevents the plant ointment from being sucked away by closed negative pressure; the upper layer of the three-dimensional mesh cloth, the hydrophilic oil-repellent covering film and the porous dressing are provided with through holes to form a channel, the administration tube is arranged in the three-dimensional mesh cloth through one end of the channel and used for continuously administering the plant ointment and dispersing the plant ointment in the three-dimensional mesh cloth, the other end of the administration tube extends out of the attached sucker to be connected with the outer side of the three-dimensional mesh cloth and continuously administering the plant ointment to the plant, and the administration tube is fixed at the through hole of the hydrophilic oil-repellent covering film by adopting a middle hole reinforcing ring and is prevented from being sucked away from the gap of the through holes; the sealing film is applied to the outer layer of the porous dressing to form a sealing system, and the sealing film is opened at the through hole of the porous dressing and is further sealed by the attaching sucker; the porous dressing has a porous hole communicating structure to form a full-layer drainage channel; the attaching sucker is communicated with a negative pressure source through a conduit to form a drainage channel, and meanwhile, an administration tube arranged in the conduit extends out of the outer side to be connected with a plant ointment supply device;
the thickness of the three-dimensional mesh cloth is 0.5-5 mm;
the three-dimensional mesh fabric is made of antibacterial virus component compound fibers, has rigid strength and has a three-dimensional skeleton structure for supporting negative pressure;
the plant ointment is filled in the three-dimensional mesh cloth;
the plant ointment is prepared from pure plant oil or medicinal extract oil and beeswax, and has skeleton structure;
the thickness ratio of the three-dimensional mesh cloth, the hydrophilic oil-repellent coating and the porous dressing is 1 (0.01-0.05) to 10-30.
2. The closed negative pressure drainage dressing system of claim 1, wherein the closed negative pressure drainage dressing system comprises a vacuum pump and a vacuum pump
The pure vegetable oil is one or a mixture of sesame oil, castor oil, olive oil, sunflower seed oil, peanut oil and tea oil.
3. The closed negative pressure drainage dressing system according to claim 1, wherein the hydrophilic oil-repellent coating is made of a nanofiber material.
4. The closed negative pressure drainage dressing system according to claim 3, wherein the hydrophilic and oil-repellent coating is subjected to a hydrophilic and oil-repellent treatment.
5. The closed negative pressure drainage dressing system of claim 1, wherein the porous dressing is a polyurethane or polyvinyl alcohol sponge or chitosan sponge or fibroin sponge.
6. The closed negative pressure drainage dressing system according to claim 1, wherein the antibacterial and antiviral component is 3-hydroxybutyrate oligomer with a degree of polymerization of 2-30, and the 3-hydroxybutyrate oligomer is prepared by pyrolysis of a copolymer of hydroxybutyrate and hydroxyvalerate.
7. The closed negative pressure drainage dressing system according to claim 1, wherein the three-dimensional mesh, the hydrophilic oil-repellent film and the porous dressing are bonded together by ultrasonic suture.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202110798589.4A CN113520720B (en) | 2021-07-15 | 2021-07-15 | Closed negative pressure drainage dressing system |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202110798589.4A CN113520720B (en) | 2021-07-15 | 2021-07-15 | Closed negative pressure drainage dressing system |
Publications (2)
Publication Number | Publication Date |
---|---|
CN113520720A CN113520720A (en) | 2021-10-22 |
CN113520720B true CN113520720B (en) | 2022-09-30 |
Family
ID=78099291
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202110798589.4A Active CN113520720B (en) | 2021-07-15 | 2021-07-15 | Closed negative pressure drainage dressing system |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN113520720B (en) |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102274574A (en) * | 2011-06-02 | 2011-12-14 | 陈德华 | Surgical wound surface closed negative pressure drainage device |
CN202113475U (en) * | 2011-06-02 | 2012-01-18 | 陈德华 | Sealed vacuum drainage device for surgical wounds |
CN202822443U (en) * | 2012-05-07 | 2013-03-27 | 钟春燕 | Closed-type negative pressure drainage device |
CN203244673U (en) * | 2013-05-08 | 2013-10-23 | 中国人民解放军第四五五医院 | Sealed negative pressure drainage device containing nano-silver polyurethane dressing |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2010082102A (en) * | 2008-09-30 | 2010-04-15 | Nitto Denko Corp | Adhesive tape or sheet for application to skin, and method for producing the same |
CN203408163U (en) * | 2013-08-14 | 2014-01-29 | 朱新生 | Novel compound foam material negative-pressure absorption device |
CN111050711B (en) * | 2017-07-29 | 2022-05-27 | 林正纶 | Anti-deformation wound treatment devices and related methods of use |
CN107693213B (en) * | 2017-11-06 | 2024-04-30 | 侯强 | Degradable dressing for wound negative pressure treatment |
CN211326142U (en) * | 2019-12-06 | 2020-08-25 | 河南汇博医疗股份有限公司 | Closed negative pressure drainage wound protection material system |
-
2021
- 2021-07-15 CN CN202110798589.4A patent/CN113520720B/en active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102274574A (en) * | 2011-06-02 | 2011-12-14 | 陈德华 | Surgical wound surface closed negative pressure drainage device |
CN202113475U (en) * | 2011-06-02 | 2012-01-18 | 陈德华 | Sealed vacuum drainage device for surgical wounds |
CN202822443U (en) * | 2012-05-07 | 2013-03-27 | 钟春燕 | Closed-type negative pressure drainage device |
CN203244673U (en) * | 2013-05-08 | 2013-10-23 | 中国人民解放军第四五五医院 | Sealed negative pressure drainage device containing nano-silver polyurethane dressing |
Also Published As
Publication number | Publication date |
---|---|
CN113520720A (en) | 2021-10-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US20200261276A1 (en) | Post-Operative Hybrid Dressing To Optimize Skin-Grafting Procedures In Reconstructive Surgery | |
EP3672655B1 (en) | Biomaterial and methods of making and using said biomaterial | |
EP3104817B1 (en) | Systems and methods for tissue healing | |
TWI445555B (en) | Dressing comprising active components of centella asiatica and use of the same | |
CN211750464U (en) | Negative pressure wound dressing material and negative pressure wound therapy device | |
CN103394155B (en) | Disposable portable negative pressure wound surface therapy system | |
CN107617121B (en) | Biological induction active dressing for skin wound surface and preparation method and application thereof | |
CN101669855A (en) | Wound-protecting product with disposable negative pressure drainage | |
CN107496972B (en) | Anti-adhesion wet dressing for promoting healing of burn wound and preparation method thereof | |
CN103120803A (en) | Preparation method of bacterial cellulose composite chitosan moist antimicrobial dressing | |
CN202822443U (en) | Closed-type negative pressure drainage device | |
CN105169464B (en) | A kind of natural honey wound dressing and preparation method and application | |
CN215020462U (en) | Wound bioactive glass wound surface gel dressing device with disinfection function for wounds | |
CN114225090A (en) | Chitosan-based nanofiber wound dressing with adhesion and antibacterial performance and preparation method thereof | |
CN113520720B (en) | Closed negative pressure drainage dressing system | |
CN101879307A (en) | Preparation for repairing active cells | |
CN105664226A (en) | Medical composite dressing and preparation method thereof | |
CN109550076B (en) | Medical silicone ozone oil vaseline dressing and wound care patch based on dressing | |
CN206508296U (en) | A kind of super water-absorbent foam dressing | |
CN109432483B (en) | Medical dressing for accelerating wound healing and preparation method and application thereof | |
US9439808B2 (en) | Skin substitute and wound dressing with added anti-scar compound | |
CN103893816B (en) | Method for preparing composite amniotic extracellular matrix dressing of bacterial cellulose containing plant ingredients | |
CN203408345U (en) | Disposable portable negative-pressure wound treatment kit | |
CN109432479A (en) | A kind of antibacterial anti hemorrhagic hydrocolloid oil yarn and preparation method thereof | |
CN109276748B (en) | Anti-adhesion healing-promoting antibacterial hydrocolloid dressing and preparation method thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant |