CN113519888A - Electronic atomized liquid - Google Patents
Electronic atomized liquid Download PDFInfo
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- CN113519888A CN113519888A CN202110888490.3A CN202110888490A CN113519888A CN 113519888 A CN113519888 A CN 113519888A CN 202110888490 A CN202110888490 A CN 202110888490A CN 113519888 A CN113519888 A CN 113519888A
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- nicotine
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- arecoline
- atomized liquid
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- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/10—Chemical features of tobacco products or tobacco substitutes
- A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
- A24B15/167—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes in liquid or vaporisable form, e.g. liquid compositions for electronic cigarettes
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- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
- A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
- A24F40/40—Constructional details, e.g. connection of cartridges and battery parts
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- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
- A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
- A24F40/40—Constructional details, e.g. connection of cartridges and battery parts
- A24F40/42—Cartridges or containers for inhalable precursors
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- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses an electronic atomized liquid, which simultaneously contains nicotine and arecoline, wherein the nicotine is a combination of at least one of plant purified nicotine, artificially synthesized nicotine, nicotine salt and a tobacco extract containing nicotine, and the arecoline is a combination of at least one of plant purified arecoline, artificially synthesized arecoline, an arecoline extract and other substances containing arecoline.
Description
Technical Field
The invention relates to the technical field of electronic cigarettes, in particular to electronic atomized liquid.
Background
The electronic atomization liquid is also called tobacco tar, tobacco juice, atomization liquid and the like, mainly comprises nicotine, propylene glycol, glycerol, essence, water and the like, and is a main substance of the electronic cigarette cartridge. Although scientific verification proves that the electronic cigarette rarely produces carcinogens such as tar and the like and reduces the harm by about 90-95% compared with the traditional flue-cured tobacco, the old smokers generally dislike the electronic cigarette, wherein the main reason is slow addiction elimination (the addiction elimination is the experience of physiological satisfaction when the smokers absorb nicotine). In addition, it is found that the addiction removing performance of the electronic cigarette can be close to that of the traditional flue-cured tobacco only when the nicotine concentration in the atomized liquid reaches 30-50 mg/ml (the mass concentration is converted to be about 2.55-4.25% according to the density of the atomized liquid), but many countries and regions strictly limit the upper limit of the nicotine concentration in the atomized liquid, for example, the nicotine concentration is limited to be not more than 20mg/ml in the European Union, and the nicotine concentration is limited to be not more than 10mg/ml in Korea. These limitations obviously reduce the addiction-relieving effect of electronic cigarettes, with the risk of diverting users of electronic cigarettes to traditional flue-cured tobacco, however, there is an increasing trend towards countries and regions where such restrictions on nicotine concentration in the atomized liquid are implemented.
Disclosure of Invention
The invention mainly solves the technical problem of how to improve the addiction eliminating performance of the electronic atomized liquid, in particular to the electronic atomized liquid with low nicotine concentration.
In order to solve the technical problems, the invention adopts a technical scheme that: an electronic atomized liquid is provided, which is characterized in that the atomized liquid contains nicotine and arecoline at the same time. The nicotine and the arecoline are derived from the artificial synthesis and the nature, wherein the nicotine is at least one of the combination of plant purified nicotine, artificial synthesized nicotine, nicotine salt, nicotine-containing tobacco extract and other nicotine-containing substances, and the arecoline is at least one of the combination of plant purified arecoline, artificial synthesized arecoline, arecoline extract and other arecoline-containing substances.
Generally, the plant purification adopts the procedures of organic solvent extraction, distillation separation, multiple purification and the like to obtain a single target product with higher purity, the plant extract adopts the procedures of water boiling, dissolved liquid concentration or drying into powder and the like to obtain a mixture containing the target product but with low purity, and the specific concentration of the target product in the plant extract or the plant extract can be chemically analyzed by adopting instruments and equipment such as GC-MS or HPLC and the like. The artificial synthesized nicotine, nicotine salt, nicotine purified product, nicotine extract, artificial synthesized arecoline, plant purified arecoline and arecoline extract are all commodities which can be legally purchased in the market, and the detection of the purity of nicotine or arecoline in various products is also the work which can be implemented by technicians in the field without creative work. In addition, the other components in the electronic atomization liquid include but are not limited to at least one combination of propylene glycol, glycerol, water, essence and additives.
In a preferred embodiment of the present invention, the formulation of the electronic atomization liquid is as follows:
0.1 to 24 parts by weight of nicotine
Arecoline 0.01-24 weight parts
0.1 to 100 parts by weight of water
0 to 160 parts by weight of propylene glycol
0 to 160 parts by weight of glycerol
0-36 parts of essence
0 to 36 parts by weight of an additive
Wherein the nicotine is purified from plant, artificial nicotine, nicotine salt, nicotine-containing tobacco extract, etc. and purified product (C) of nicotine contained therein is added10H14N2) The weight is based;
wherein the arecoline is extracted from plant, artificially synthesized arecoline, and Arecae semen extract8H13NO2) The weight is based;
wherein the essence includes, but is not limited to, cooling agent essence, sweetener essence, fruit essence, tobacco essence, meat essence, wine essence, food essence, plant herb essence, animal spice essence, etc. The essence is a combination of at least one of natural essence, animal and plant purified essence or artificially synthesized essence; cooling agent flavors such as menthol flavor, WS-23 (N-ethyl-L-menthyl formamide) flavor, WS-3 (menthanecarboxamide) flavor and the like, sweeteners such as sucralose flavor, neotame flavor and the like, fruit flavors such as linalool flavor, β -damascenone flavor, passion fruit flavor and the like, meat flavors such as animal fat, artificial ethyl maltol and the like, food flavors such as mung bean flavor and the like, wine flavors such as ethyl hexanoate and the like, plant herbal flavors such as rose extract and the like, animal flavors such as musk extract and the like;
wherein, the additives include but are not limited to tea extract, lavender extract, lily extract, licorice extract and the like, can be in the form of concentrated solution or powder, and can meet different additional functional requirements of special customers such as nerve calming, lung moistening, hypnosis and the like;
wherein, one part of water comes from the nicotine raw material, the arecoline raw material, the propylene glycol, the glycerol, the essence and the moisture brought by the additive, the other part of water comes from the additional addition, and the proportion of the two parts of water is not limited.
The manufacturing process of the electronic atomized liquid of the invention comprises the following steps: directly mixing nicotine (nicotine, nicotine salt or tobacco extract), arecoline (artificial arecoline, arecoline extract or other substances containing arecoline), propylene glycol, glycerol, water, essence and additives uniformly according to the formula, or heating or ultrasonic vibrating to rapidly dissolve the tobacco extract or the arecoline extract into the electronic atomized liquid.
The electronic atomization liquid can be directly injected into a steam type electronic cigarette cartridge, and can also be doped into fuming particles or fuming thin slices of a heating non-combustion type electronic cigarette (HNB) cartridge by means of conventional equipment and processes. For example, a proper amount of electronic atomized liquid and plant dry particles or artificial fibers are uniformly mixed and are subjected to screw extrusion, rounding, shot blasting, drying and sieving to prepare fuming particles; uniformly mixing a proper amount of electronic atomized liquid and plant dry particles or artificial fibers, rolling, drying and demolding to obtain fuming sheets; after dried plant particles or artificial fibers are soaked in water for pulping, a paper machine is used for manufacturing a fiber sheet base, a proper amount of electronic atomized liquid is uniformly coated on the surface of the fiber sheet base, and a fuming sheet is manufactured after drying and cutting; and packaging the fuming section filled with the fuming particles, the fuming thin slices or the fuming colloid, the food-grade silica gel cooling section and the filter tip section into a whole by using wrapping materials such as tipping paper and the like to obtain the HNB solid smoke cartridge.
To the surprise of the inventor: after nicotine and arecoline are simultaneously added into the electronic atomized liquid, the technology has a magical synergistic enhancement effect on the addiction-removing performance of steam electronic cigarettes and HNB electronic cigarettes, for example, a small amount of arecoline is added into the nicotine benzoate salt atomized liquid with the nicotine concentration of 2%, the mixture is uniformly stirred to form the electronic atomized liquid simultaneously containing nicotine and arecoline, and the atomized liquid can achieve the smoking addiction-removing effect of the similar nicotine benzoate salt atomized liquid with the nicotine concentration of 3% -4%.
The analysis reason of the inventor is the physiological synergistic enhancement effect of the nicotine and the arecoline, and the synergistic enhancement effect can enable the dopamine secretion amount of the cerebral Happy factor when the nicotine and the arecoline are combined to exceed the simple addition of the dopamine secretion amounts of the nicotine and the arecoline when the nicotine and the arecoline are used independently. Researches suggest that 'acetylcholine receptors (nAChRs) -dopamine secretion of nicotine-brain ventral dorsal cap area (VTA)' are nicotine reward paths when people smoke cigarettes and electronic cigarettes, the acetylcholine receptors come from a central nervous system, and arecoline can efficiently stimulate the central nerve to promote neuron secretion of the acetylcholine receptors, epinephrine and the like, or directly activate an M receptor of the VTA to enhance neuron cell changes in the VTA induced by nicotine, so that physiological pleasure of nicotine entering a human body is synergistically improved, and a better addiction relieving effect is achieved.
The beneficial effects of the technology of the invention are: the technology adds nicotine and arecoline as main components into the electronic atomized liquid at the same time, improves the physiological pleasure of a user when the user smokes the electronic cigarette by utilizing the physiological synergistic enhancement effect of the combination of the nicotine and the arecoline, particularly enables the low-concentration nicotine atomized liquid to achieve the addiction-relieving effect of the conventional high-concentration nicotine atomized liquid under the condition of complying with the regulation of nicotine concentration in the atomized liquid, and is beneficial to reducing the risk that the user turns to the conventional tobacco for the electronic cigarette. The electronic atomized liquid containing nicotine and arecoline developed by the technology can be used for liquid smoke cartridges of steam electronic cigarettes and can also be used for solid smoke cartridges of heating non-combustible electronic cigarettes. The technology utilizes an electronic cigarette mode, so that a user can simultaneously suck proper nicotine and arecoline, and oral cancer and other diseases caused by directly chewing areca nuts by people can be reduced. By using the technology, the nicotine is matched with the arecoline, so that the addiction relieving effect of more nicotine can be achieved by a user after smoking less nicotine, and the smoking amount and the serious dependence of smokers on the nicotine can be reduced.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The embodiment of the invention comprises the following steps:
16.27 parts by weight of a plant-purified nicotine having a purity of 99.7% were mixed uniformly with 12.22 parts by weight of benzoic acid having a purity of 99.9% in a container and reacted by heating (nicotine to benzoic acid molar ratio of about 1: 1) to obtain 28.49 parts by weight of a nicotinic benzoate salt (nicotine concentration of about 56.93%), designated as nicotine salt X.
16.26 parts by weight of synthetic nicotine having a purity of 99.8% and 16.30 parts by weight of tartaric acid having a purity of 99.5% were mixed in a container and reacted by heating (about 1: 1 in terms of the mass of nicotine and tartaric acid) to obtain 32.56 parts by weight of nicotine tartrate salt (about 49.84% in nicotine concentration) labeled as nicotine salt Y.
16.27 parts by weight of plant purified nicotine with purity of 99.7%, 16.26 parts by weight of synthetic nicotine with purity of 99.8% and 32.6466 parts by weight of capric acid with purity of 99.5% are mixed uniformly in a container and heated to react (the mass ratio of nicotine and capric acid is about 1: 1), so as to prepare about 65.1766 parts by weight of nicotine decanoate salt (the nicotine concentration is about 49.8479%), which is marked as nicotine salt Z.
Comparative example 1
In a container, 0.1005 parts by weight of purified plant nicotine (about 0.1 parts by weight of nicotine) having a purity of 99.5% and 9.8995 parts by weight of water were sequentially added, and stirred uniformly to obtain 10 parts by weight of atomized liquid, in which the nicotine concentration was about 1%, and which was designated as atomized liquid a 1.
Comparative example 2
In a container, 1.6032 parts by weight of synthetic nicotine (about 1.60 parts by weight of nicotine) having a purity of 99.8%, 0.1 part by weight of water, 34.2824 parts by weight of propylene glycol, 34 parts by weight of glycerin, 2.0144 parts by weight of menthol as a cooling agent, and 8 parts by weight of sucralose as a sweetener were sequentially added, and stirred uniformly to obtain 80 parts by weight of atomized liquid, in which the nicotine concentration was about 2%, and labeled as atomized liquid B1.
Comparative example 3
8.4314 parts by weight of nicotine salt X (containing about 4.8 parts by weight of nicotine) with nicotine concentration of 56.93%, 1 part by weight of water, 100.5686 parts by weight of propylene glycol, 30 parts by weight of glycerol, 2 parts by weight of menthol cooling agent, 16 parts by weight of sucralose sweetener and 2 parts by weight of linalool essence are sequentially added into a container and uniformly stirred to obtain 160 parts by weight of atomized liquid, wherein the nicotine concentration is about 3%, and the mark is atomized liquid C1.
Comparative example 4
4.8241 parts by weight of synthetic nicotine with the purity of 99.5% (containing about 4.8 parts by weight of nicotine), 8.4314 parts by weight of nicotine salt X with the nicotine concentration of 56.93% (containing about 4.8 parts by weight of nicotine), 30 parts by weight of water, 20 parts by weight of propylene glycol, 136.7445 parts by weight of glycerol, 10 parts by weight of menthol cooling agent, 5 parts by weight of neotame essence, 10 parts by weight of beta-damascenone essence and 15 parts by weight of tea extract additive are sequentially added into a container and uniformly stirred to obtain 240 parts by weight of atomized liquid, wherein the nicotine concentration is about 4%, and the atomized liquid is marked as atomized liquid D1.
Comparative example 5
16.0488 parts by weight of nicotine salt Z (containing 8 parts by weight of nicotine) with nicotine concentration of about 49.8479%, 8.0402 parts by weight of plant purified nicotine (containing 8 parts by weight of nicotine) with nicotine concentration of 99.5%, 8.0160 parts by weight of artificial nicotine (containing 8 parts by weight of nicotine) with nicotine concentration of 99.8%, 100 parts by weight of water, 160 parts by weight of propylene glycol, 35.895 parts by weight of glycerol, 10 parts by weight of WS-23 cooling agent, 16 parts by weight of sucralose essence, 10 parts by weight of ethyl maltol essence, 18 parts by weight of tea extract additive and 18 parts by weight of lavender extract additive are sequentially added into a container and uniformly stirred to obtain 400 parts by weight of atomized liquid, wherein the nicotine concentration is about 6%, and the atomized liquid is marked as F1.
Comparative example 6
2.0064 parts by weight of nicotine salt Y (containing about 1 part by weight of nicotine) with nicotine concentration of about 49.84%, 1.002 parts by weight of synthetic nicotine (containing about 1 part by weight of nicotine) with purity of about 99.8%, 0.3 part by weight of water, 30 parts by weight of propylene glycol, 36.6916 parts by weight of glycerol, 15 parts by weight of lily extract additive and 15 parts by weight of licorice extract additive are added into a container in sequence and stirred uniformly to obtain 100 parts by weight of atomized liquid, wherein the concentration of nicotine is about 2% and is marked as atomized liquid H1.
Comparative example 7
In a container, 2 parts by weight of a tobacco extract (containing about 1 part by weight of nicotine) having a nicotine content of about 50%, 3.5131 parts by weight of a nicotine salt X (containing about 2 parts by weight of nicotine) having a nicotine concentration of about 56.93%, 0.3 part by weight of water, 32.1869 parts by weight of propylene glycol, 34 parts by weight of glycerin, 20 parts by weight of a rose extract essence, and 8 parts by weight of a musk extract essence were sequentially added, and uniformly stirred to obtain 100 parts by weight of an atomized liquid, in which the nicotine concentration was about 3%, and the mark was atomized liquid K1.
Example 1
In a container, 0.1005 parts by weight of plant purified nicotine (about 0.1 parts by weight of nicotine) having a purity of 99.5%, 0.0204 parts by weight of synthetic arecoline (containing 0.02 parts by weight of arecoline) having a purity of 98%, and 9.8791 parts by weight of water were sequentially added, and stirred uniformly to obtain 10 parts by weight of atomized liquid, in which the nicotine concentration was about 1%, and the label was atomized liquid a 2.
Example 2
In a container, 1.6032 parts by weight of synthetic nicotine (about 1.60 parts by weight of nicotine) with the purity of 99.8%, 0.2824 parts by weight of plant-purified arecoline (containing 0.24 part by weight of arecoline) with the purity of 85%, 0.1 part by weight of water, 34 parts by weight of propylene glycol, 34 parts by weight of glycerol, 2.0144 parts by weight of menthol ice-cooling agent and 8 parts by weight of sucralose sweetener are sequentially added, and the mixture is uniformly stirred to obtain 80 parts by weight of atomized liquid, wherein the concentration of the nicotine is about 2%, and the mark is atomized liquid B2.
Example 3
8.4314 parts by weight of nicotine salt X (containing about 4.8 parts by weight of nicotine) with nicotine concentration of 56.93%, 0.6588 parts by weight of plant-purified arecoline with purity of 85% (containing 0.56 part by weight of arecoline), 1 part by weight of water, 99.9098 parts by weight of propylene glycol, 30 parts by weight of glycerol, 2 parts by weight of menthol ice-cooling agent, 16 parts by weight of sucralose sweetener and 2 parts by weight of linalool essence are sequentially added into a container, and the mixture is uniformly stirred to obtain 160 parts by weight of atomized liquid, wherein the nicotine concentration is about 3%, and the atomized liquid is marked as atomized liquid C2.
Example 4
4.8241 parts by weight of synthetic nicotine with the purity of 99.5% (containing about 4.8 parts by weight of nicotine), 8.4314 parts by weight of nicotine salt X with the nicotine concentration of 56.93% (containing about 4.8 parts by weight of nicotine), 0.6588 parts by weight of plant-purified arecoline with the purity of 85% (containing 0.56 part by weight of arecoline), 0.6737 parts by weight of synthetic arecoline with the nicotine concentration of 95% (containing 0.64 part by weight of arecoline), 30 parts by weight of water, 20 parts by weight of propylene glycol, 135.412 parts by weight of glycerol, 10 parts by weight of menthol ice-cooling agent, 5 parts by weight of neotame essence, 10 parts by weight of beta-damascenone essence and 15 parts by weight of tea extract additive are sequentially added into a container, and then uniformly stirred to obtain 240 parts by weight of atomized liquid, wherein the nicotine concentration is about 4%, and the atomized liquid is marked as D2.
Example 5
16.0488 parts by weight of nicotine salt Z with nicotine concentration of about 49.8479% (containing about 8 parts by weight of nicotine), 8.0402 parts by weight of plant purified nicotine with nicotine concentration of 99.5% (containing about 8 parts by weight of nicotine), 8.0160 parts by weight of artificial synthetic nicotine with nicotine concentration of 99.8% (containing about 8 parts by weight of nicotine), 10.5263 parts by weight of plant purified arecoline with purity of 95% (containing 10 parts by weight of arecoline), 10.8696 parts by weight of artificial synthetic arecoline with purity of 99.2% (containing about 10 parts by weight of arecoline), 5 parts by weight of arecoline extract with arecoline content of 80% (containing 4 parts by weight of arecoline), 100 parts by weight of water, 160 parts by weight of propylene glycol, 9.4991 parts by weight of glycerol, 10 parts by weight of WS-23 parts of coolant, 16 parts by weight of sucralose essence, 10 parts by weight of ethyl maltol essence, 18 parts by weight of tea extract additive and 18 parts by weight of lavender extract additive are sequentially added in a container, stirring was carried out uniformly to obtain 400 parts by weight of an atomized liquid in which the nicotine concentration was about 6%, and this was designated as atomized liquid F2.
Example 6
2.0064 parts by weight of nicotine salt Y (containing about 1 part by weight of nicotine) with nicotine concentration of about 49.84%, 1.002 parts by weight of synthetic nicotine (containing about 1 part by weight of nicotine) with purity of about 99.8%, 0.1053 parts by weight of plant-purified arecoline (containing 0.1 part by weight of arecoline) with purity of 95%, 0.2010 parts by weight of synthetic arecoline (containing about 0.2 part by weight of arecoline) with purity of 99.5%, 0.1538 parts by weight of arecoline extract (containing about 0.1 part by weight of arecoline) with arecoline concentration of 65%, 0.3 part by weight of water, 30 parts by weight of propylene glycol, 36.2315 parts by weight of glycerol, 15 parts by weight of lily extract additive and 15 parts by weight of licorice extract additive are added in sequence in a container, and 100 parts by weight of atomized liquid is obtained by stirring, wherein the nicotine concentration is about 2%, and the atomized liquid is marked as H2.
Example 7
In a container, 2 parts by weight of a tobacco extract (containing about 1 part by weight of nicotine) having a nicotine content of about 50%, 3.5131 parts by weight of a nicotine salt X (containing about 2 parts by weight of nicotine) having a nicotine concentration of about 56.93%, 0.4211 parts by weight of a plant-purified arecoline (containing 0.4 part by weight of arecoline) having a purity of 95%, 0.1005 part by weight of a synthetic arecoline (containing about 0.1 part by weight of arecoline) having a purity of 99.5%, 0.0769 parts by weight of an arecoline extract (containing about 0.05 part by weight of arecoline) having a arecoline concentration of 65%, 0.3 part by weight of water, 31.5884 parts by weight of propylene glycol, 34 parts by weight of glycerol, 20 parts by weight of a rose extract essence and 8 parts by weight of a musk extract essence were added in this order, and stirred uniformly to obtain 100 parts by weight of an atomized liquid, in which the nicotine concentration was about 3%, and which was labeled as atomized liquid K2.
Atomized liquid assembled electronic cigarette
In order to compare the addiction eliminating effect of the 14 electronic atomized liquids under the same condition as much as possible, 2 groups of the same-style cotton atomized core steam electronic smoking set, 8 groups of the same-style ceramic core steam electronic smoking set and 4 groups of the heating non-combustion smoking set are respectively used, each group comprises 5 completely same-style smoking sets, the electronic smoking sets can be directly purchased from the market, and the operation of assembling the atomized liquid with the electronic cigarette is as follows.
2 ml of atomized liquid A1 and atomized liquid A2 are respectively injected into 2 groups of cotton atomization core steam electronic smoking sets of the same type, and as the water content in A1 and A2 is high and the atomization temperature is low, the 2 groups of electronic cigarettes can be normally smoked when the output power is about 5 watts, and 1 electronic cigarette selected from each group respectively represents atomized liquid A1 and atomized liquid A2.
2 ml of atomized liquid B1, atomized liquid B2, atomized liquid C1, atomized liquid C2, atomized liquid D1, atomized liquid D2, atomized liquid F1 and atomized liquid F2 are respectively injected into 10 groups of ceramic core steam electronic smoking sets, the 10 groups of electronic cigarettes can be tested to be normally smoked, and 1 electronic cigarette selected from each group respectively represents atomized liquid B1, B2, C1, C2, D1, D2, F1 and F2.
According to the conventional process and equipment of the HNB fuming thin slice, the atomized liquid H1 and the atomized liquid H2 with the same weight are respectively and uniformly mixed with a proper amount of plant dry particles, and the mixture is rolled, dried and demoulded to prepare two types of fuming thin slices, and a fuming section, a food-grade silica gel cooling section and a filter section which are filled in the fuming thin slices are packaged into a whole by using a tipping paper packaging material, namely two types of HNB solid smoke bombs are correspondingly prepared by using the atomized liquid H1 and the atomized liquid H2.
According to the conventional process and equipment of the HNB fuming thin sheet, a proper amount of artificial fiber is soaked in water for pulping, a paper machine is used for manufacturing a fiber sheet base, atomized liquid K1 and atomized liquid K2 in the same weight portion are uniformly coated on the surface of the fiber sheet base, the fuming thin sheet is manufactured after drying and cutting, a fuming section, a food-grade silica gel cooling section and a filter tip section which are filled in the fuming thin sheet are packaged into a whole by a tipping paper packaging material, and two HNB solid smoke bombs are correspondingly manufactured by the atomized liquid K1 and the atomized liquid K2.
The 4 HNB solid cartridges are tested by using the same type of heating non-combustible smoking set and can be normally sucked and used, and the 4 HNB solid cartridges respectively represent H1, H2, K1 and K2 electronic atomized liquids used by the HNB solid cartridges.
Atomized liquid addiction suction evaluation:
addiction relief is a physiological satisfaction experience when smokers smoke cigarettes or electronic cigarettes, relates to human brain neuroscience such as nicotine absorption-acetylcholine ligand-dopamine reward and the like, and has larger life individual difference, and no reliable scientific experiment can accurately quantify nicotine absorption-acetylcholine ligand-dopamine addiction all over the world so far. The manual smoking and recording of the number of addiction-relieving mouths is a common addiction-relieving test method in the industry at present.
In order to study and compare the addiction relieving effect of the electronic cigarette sample containing the 14 types of atomized liquid, 10 evaluators in each sample sequentially and blindly measure the number of suction ports when the suction record meets the addiction relieving physiological requirement, in order to avoid the cumulative influence of nicotine residue in a first-measured sample on a later-measured sample in a human body (the nicotine half-life period is about 2 hours), the inventor stipulates that each person can only test 1 steam electronic cigarette sample or 1 type of HNB electronic cigarette sample every day, preferably, the suction test is started at 9 am and each port is separated by 1 minute (in order to avoid the delay of the rebound of HNB samples, the type of HNB smoking set can be used for replacing and testing the sample, and the separation time of each port is ensured to be consistent), and the comprehensive evaluation results are shown in table 1:
TABLE 1 addiction eliminating mouth number recording table for fourteen atomizing liquid electronic cigarette samples
As can be seen from table 1: the smoking addiction-relieving mouth number of the same atomized liquid and the electronic cigarette sample thereof is that 10 evaluators really have little individual difference, but the addiction-relieving performance of the 14 atomized liquids can be relatively accurately fed back by calculating the average mouth number.
To compare the properties of the tobacco tar of the comparative example and the 14-style tobacco tar of the example more visually, table 2 is prepared as follows:
TABLE 2 comparison of addiction-relieving oral numbers of comparative examples and examples
As can be seen from tables 1 and 2: the higher the nicotine concentration in the atomized liquid is, the fewer the nicotine addiction-relieving mouths are, and the result is consistent with the result of a user smoking traditional cigarettes with different nicotine concentrations and other electronic cigarettes; (7 examples) the atomized liquid containing nicotine and arecoline has less addiction-relieving mouth number than the atomized liquid containing no arecoline and having the same nicotine concentration (7 comparative examples), which shows that the atomized liquid has better addiction-relieving effect; the atomized liquid containing nicotine and arecoline is used in a steam electronic cigarette and a heating non-combustible electronic cigarette, and the addiction removing performance of the electronic cigarette is not the simple superposition of the nicotine and the arecoline, but the atomized liquid and the arecoline have a magical synergistic enhancement effect after being combined, so that the atomized liquid containing nicotine and arecoline can achieve the addiction removing number of the atomized liquid containing nicotine and arecoline with higher concentration under the synergistic effect of a small amount of arecoline, for example, in example 2 (nicotine concentration 2% + arecoline concentration 0.3%), the average addiction removing oral prescription is 6, and the atomized liquid containing nicotine and arecoline reach the addiction removing effect of the atomized liquid containing 3.5% of nicotine concentration between 7 mouths in a comparative example 3 (nicotine concentration 3%) and 5 mouths in a comparative example 4 (nicotine concentration 4%); the electronic atomized liquid simultaneously containing nicotine and arecoline can reduce the addiction-relieving mouth number of a user on steam electronic cigarettes and heating non-burning electronic cigarettes, namely improve the addiction-reducing property.
In conclusion, the electronic atomized liquid containing nicotine and arecoline provided by the invention improves the addiction eliminating effect of the electronic atomized liquid by utilizing the magical synergistic enhancement effect of the compatibility of nicotine and arecoline, particularly enables the atomized liquid with low nicotine concentration to achieve the addiction eliminating effect of the atomized liquid with higher nicotine concentration, meets the requirement of more and more national and regional regulations on the upper limit of nicotine concentration in the atomized liquid, can quickly realize the addiction eliminating requirement of electronic cigarette users, and reduces the risk of turning the electronic cigarette users to the traditional cigarettes.
The above description is only an embodiment of the present invention, and not intended to limit the scope of the present invention, and all modifications of equivalent structures and equivalent processes, or direct and indirect applications in other related fields, which are made by the contents of the present specification, are included in the scope of the present invention.
Claims (5)
1. An electronic atomization liquid is characterized in that the electronic atomization liquid simultaneously contains nicotine and arecoline, wherein the nicotine is a combination of at least one of plant purified nicotine, synthetic nicotine, nicotine salt and a tobacco extract containing nicotine, and the arecoline is a combination of at least one of plant purified arecoline, synthetic arecoline and an arecoline-containing arecoline extract.
2. The electronically atomized liquid of claim 1, further comprising water, propylene glycol, glycerin, a fragrance, and an additive.
3. The electronically atomized liquid of claim 2, wherein the specific gravities of the components in the electronically atomized liquid are:
0.1 to 24 parts by weight of nicotine
Arecoline 0.01-24 weight parts
0.1 to 100 parts by weight of water
0 to 160 parts by weight of propylene glycol
0 to 160 parts by weight of glycerol
0-36 parts of essence
0-36 parts of additive.
4. The electronic atomized liquid of claim 2, wherein the essence is a combination of at least one of cooling essence, sweetener essence, fruit essence, tobacco essence, meat essence, wine essence, food essence, plant herbal essence, and animal essence.
5. The electronically atomized liquid of claim 2, wherein the additive is a combination of at least one of tea extract, lavender extract, lily extract, and licorice extract.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
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