CN113491648A - 一种具有祛痘和祛痘印功效的精华乳及其制备方法 - Google Patents
一种具有祛痘和祛痘印功效的精华乳及其制备方法 Download PDFInfo
- Publication number
- CN113491648A CN113491648A CN202010252242.5A CN202010252242A CN113491648A CN 113491648 A CN113491648 A CN 113491648A CN 202010252242 A CN202010252242 A CN 202010252242A CN 113491648 A CN113491648 A CN 113491648A
- Authority
- CN
- China
- Prior art keywords
- vitex agnus
- acne
- essence
- castus extract
- weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000000694 effects Effects 0.000 title claims abstract description 45
- 208000002874 Acne Vulgaris Diseases 0.000 title claims abstract description 39
- 206010000496 acne Diseases 0.000 title claims abstract description 39
- 238000002360 preparation method Methods 0.000 title claims abstract description 27
- 235000013336 milk Nutrition 0.000 title claims abstract description 18
- 239000008267 milk Substances 0.000 title claims abstract description 18
- 210000004080 milk Anatomy 0.000 title claims abstract description 18
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims abstract description 69
- 239000003094 microcapsule Substances 0.000 claims abstract description 68
- 239000009186 Vitex agnus castus extract Substances 0.000 claims abstract description 66
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 59
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 27
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims abstract description 25
- 239000000463 material Substances 0.000 claims abstract description 12
- 229940081733 cetearyl alcohol Drugs 0.000 claims abstract description 10
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 claims abstract description 10
- 229960005150 glycerol Drugs 0.000 claims abstract description 9
- 239000000230 xanthan gum Substances 0.000 claims abstract description 9
- 235000010493 xanthan gum Nutrition 0.000 claims abstract description 9
- 229920001285 xanthan gum Polymers 0.000 claims abstract description 9
- 229940082509 xanthan gum Drugs 0.000 claims abstract description 9
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims abstract description 8
- 229920002125 Sokalan® Polymers 0.000 claims abstract description 7
- 239000000654 additive Substances 0.000 claims abstract description 7
- 229960001631 carbomer Drugs 0.000 claims abstract description 7
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 claims abstract description 6
- -1 polydimethylsiloxane Polymers 0.000 claims abstract description 6
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 claims abstract description 5
- 239000004205 dimethyl polysiloxane Substances 0.000 claims abstract description 5
- 229960005323 phenoxyethanol Drugs 0.000 claims abstract description 5
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims abstract description 5
- LADGBHLMCUINGV-UHFFFAOYSA-N tricaprin Chemical compound CCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCC)COC(=O)CCCCCCCCC LADGBHLMCUINGV-UHFFFAOYSA-N 0.000 claims abstract description 5
- INSRQEMEVAMETL-UHFFFAOYSA-N decane-1,1-diol Chemical compound CCCCCCCCCC(O)O INSRQEMEVAMETL-UHFFFAOYSA-N 0.000 claims abstract description 4
- 229930182478 glucoside Natural products 0.000 claims abstract description 4
- 150000008131 glucosides Chemical class 0.000 claims abstract description 4
- LXAHHHIGZXPRKQ-UHFFFAOYSA-N 5-fluoro-2-methylpyridine Chemical compound CC1=CC=C(F)C=N1 LXAHHHIGZXPRKQ-UHFFFAOYSA-N 0.000 claims abstract 2
- 239000000839 emulsion Substances 0.000 claims description 41
- 238000003756 stirring Methods 0.000 claims description 39
- 239000011259 mixed solution Substances 0.000 claims description 24
- 230000001954 sterilising effect Effects 0.000 claims description 22
- 238000001816 cooling Methods 0.000 claims description 21
- 238000001694 spray drying Methods 0.000 claims description 21
- 239000000243 solution Substances 0.000 claims description 19
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims description 18
- 229920006037 cross link polymer Polymers 0.000 claims description 18
- 238000005303 weighing Methods 0.000 claims description 18
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims description 17
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 claims description 16
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical class CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims description 16
- 229920000858 Cyclodextrin Polymers 0.000 claims description 16
- 150000002148 esters Chemical class 0.000 claims description 16
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 claims description 16
- 235000010413 sodium alginate Nutrition 0.000 claims description 16
- 239000000661 sodium alginate Substances 0.000 claims description 16
- 229940005550 sodium alginate Drugs 0.000 claims description 16
- 238000004659 sterilization and disinfection Methods 0.000 claims description 15
- 238000010438 heat treatment Methods 0.000 claims description 13
- 238000000034 method Methods 0.000 claims description 13
- 239000000843 powder Substances 0.000 claims description 12
- 230000002829 reductive effect Effects 0.000 claims description 12
- 239000000284 extract Substances 0.000 claims description 6
- 239000007788 liquid Substances 0.000 claims description 6
- 235000009347 chasteberry Nutrition 0.000 claims description 5
- 239000006071 cream Substances 0.000 claims description 4
- 208000020154 Acnes Diseases 0.000 claims description 3
- 239000003109 Disodium ethylene diamine tetraacetate Substances 0.000 claims description 3
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 claims description 3
- 235000019301 disodium ethylene diamine tetraacetate Nutrition 0.000 claims description 3
- 239000006210 lotion Substances 0.000 claims description 3
- AEIJTFQOBWATKX-UHFFFAOYSA-N octane-1,2-diol Chemical compound CCCCCCC(O)CO AEIJTFQOBWATKX-UHFFFAOYSA-N 0.000 claims description 3
- 241000532412 Vitex Species 0.000 claims description 2
- 238000002156 mixing Methods 0.000 claims description 2
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 2
- 239000005635 Caprylic acid (CAS 124-07-2) Substances 0.000 claims 1
- 229940080421 coco glucoside Drugs 0.000 claims 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims 1
- 229960002446 octanoic acid Drugs 0.000 claims 1
- 238000002474 experimental method Methods 0.000 abstract description 3
- 230000004888 barrier function Effects 0.000 abstract description 2
- 210000003491 skin Anatomy 0.000 description 75
- 238000012360 testing method Methods 0.000 description 70
- 239000000523 sample Substances 0.000 description 56
- 239000003921 oil Substances 0.000 description 36
- 230000000052 comparative effect Effects 0.000 description 31
- 230000008859 change Effects 0.000 description 23
- 206010015150 Erythema Diseases 0.000 description 19
- 230000005764 inhibitory process Effects 0.000 description 13
- 231100000321 erythema Toxicity 0.000 description 12
- 230000002401 inhibitory effect Effects 0.000 description 12
- 241000894006 Bacteria Species 0.000 description 10
- 210000001061 forehead Anatomy 0.000 description 10
- 239000002994 raw material Substances 0.000 description 9
- 238000011156 evaluation Methods 0.000 description 8
- 238000005259 measurement Methods 0.000 description 8
- 241000186427 Cutibacterium acnes Species 0.000 description 7
- 229940055019 propionibacterium acne Drugs 0.000 description 7
- 230000008569 process Effects 0.000 description 6
- 239000002537 cosmetic Substances 0.000 description 5
- 230000003247 decreasing effect Effects 0.000 description 5
- 239000000341 volatile oil Substances 0.000 description 5
- 230000001580 bacterial effect Effects 0.000 description 4
- 239000001963 growth medium Substances 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 230000028327 secretion Effects 0.000 description 4
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Natural products C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 description 3
- 235000001667 Vitex agnus castus Nutrition 0.000 description 3
- 244000063464 Vitex agnus-castus Species 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 3
- 230000002708 enhancing effect Effects 0.000 description 3
- 230000001965 increasing effect Effects 0.000 description 3
- 238000012216 screening Methods 0.000 description 3
- 230000008591 skin barrier function Effects 0.000 description 3
- 230000007480 spreading Effects 0.000 description 3
- 238000003892 spreading Methods 0.000 description 3
- 238000007619 statistical method Methods 0.000 description 3
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 description 2
- 241000233866 Fungi Species 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 241001073567 Verbenaceae Species 0.000 description 2
- 230000000996 additive effect Effects 0.000 description 2
- 238000009835 boiling Methods 0.000 description 2
- 238000004364 calculation method Methods 0.000 description 2
- 238000007405 data analysis Methods 0.000 description 2
- 239000008367 deionised water Substances 0.000 description 2
- 229910021641 deionized water Inorganic materials 0.000 description 2
- 238000013400 design of experiment Methods 0.000 description 2
- 238000009826 distribution Methods 0.000 description 2
- POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical compound CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 description 2
- 210000002615 epidermis Anatomy 0.000 description 2
- 210000004709 eyebrow Anatomy 0.000 description 2
- 230000001815 facial effect Effects 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- IPCSVZSSVZVIGE-UHFFFAOYSA-N hexadecanoic acid Chemical compound CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 239000003112 inhibitor Substances 0.000 description 2
- 238000002372 labelling Methods 0.000 description 2
- 244000005700 microbiome Species 0.000 description 2
- 230000003020 moisturizing effect Effects 0.000 description 2
- 238000007747 plating Methods 0.000 description 2
- 229960003387 progesterone Drugs 0.000 description 2
- 239000000186 progesterone Substances 0.000 description 2
- 238000010992 reflux Methods 0.000 description 2
- 210000002966 serum Anatomy 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 1
- OYHQOLUKZRVURQ-NTGFUMLPSA-N (9Z,12Z)-9,10,12,13-tetratritiooctadeca-9,12-dienoic acid Chemical compound C(CCCCCCC\C(=C(/C\C(=C(/CCCCC)\[3H])\[3H])\[3H])\[3H])(=O)O OYHQOLUKZRVURQ-NTGFUMLPSA-N 0.000 description 1
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 1
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 description 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 description 1
- 241001233914 Chelidonium majus Species 0.000 description 1
- 241000192125 Firmicutes Species 0.000 description 1
- 241000207923 Lamiaceae Species 0.000 description 1
- 239000005639 Lauric acid Substances 0.000 description 1
- 238000000585 Mann–Whitney U test Methods 0.000 description 1
- 239000005642 Oleic acid Substances 0.000 description 1
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 description 1
- 235000021314 Palmitic acid Nutrition 0.000 description 1
- 206010039792 Seborrhoea Diseases 0.000 description 1
- 238000011869 Shapiro-Wilk test Methods 0.000 description 1
- 235000021355 Stearic acid Nutrition 0.000 description 1
- 229910021536 Zeolite Inorganic materials 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 230000003255 anti-acne Effects 0.000 description 1
- 229940121363 anti-inflammatory agent Drugs 0.000 description 1
- 239000002260 anti-inflammatory agent Substances 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000010219 correlation analysis Methods 0.000 description 1
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 238000002845 discoloration Methods 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 238000005485 electric heating Methods 0.000 description 1
- 238000005538 encapsulation Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000000686 essence Substances 0.000 description 1
- 238000013401 experimental design Methods 0.000 description 1
- 210000000887 face Anatomy 0.000 description 1
- 150000002216 flavonol derivatives Chemical class 0.000 description 1
- 235000021588 free fatty acids Nutrition 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 210000004907 gland Anatomy 0.000 description 1
- 239000004519 grease Substances 0.000 description 1
- 238000010191 image analysis Methods 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 230000037312 oily skin Effects 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 235000021313 oleic acid Nutrition 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000036555 skin type Effects 0.000 description 1
- 235000011121 sodium hydroxide Nutrition 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 230000003595 spectral effect Effects 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 230000000153 supplemental effect Effects 0.000 description 1
- 230000009182 swimming Effects 0.000 description 1
- TUNFSRHWOTWDNC-HKGQFRNVSA-N tetradecanoic acid Chemical compound CCCCCCCCCCCCC[14C](O)=O TUNFSRHWOTWDNC-HKGQFRNVSA-N 0.000 description 1
- 235000021122 unsaturated fatty acids Nutrition 0.000 description 1
- 150000004670 unsaturated fatty acids Chemical class 0.000 description 1
- 238000004383 yellowing Methods 0.000 description 1
- 239000010457 zeolite Substances 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/11—Encapsulated compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
- A61K8/553—Phospholipids, e.g. lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/733—Alginic acid; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/738—Cyclodextrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8152—Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/56—Compounds, absorbed onto or entrapped into a solid carrier, e.g. encapsulated perfumes, inclusion compounds, sustained release forms
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Cosmetics (AREA)
Abstract
Description
样品1 | 实施例1制备穗花牡荆提取物微囊 |
样品2 | 实施例2制备穗花牡荆提取物微囊 |
样品3 | 实施例3制备穗花牡荆提取物微囊 |
样品4 | 对比例1制备穗花牡荆提取物微囊 |
样品5 | 对比例2制备穗花牡荆提取物微囊 |
样品6 | 对比例3制备穗花牡荆提取物微囊 |
样品7 | 对比例4制备穗花牡荆提取物微囊 |
样品8 | 对比例5制备穗花牡荆提取物微囊 |
样品9 | 对比例6制备穗花牡荆提取物微囊 |
样品10 | 未包裹穗花牡荆提取物 |
实验样品 | 样品1 | 样品2 | 样品3 | 样品4 | 样品5 | 样品6 | 样品7 | 样品8 | 样品9 | 样品10 |
包埋率% | 78.8 | 92.1 | 83.2 | 67.8 | 70.5 | 69.2 | 64.8 | 60.5 | 74.5 | —— |
Claims (9)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202010252242.5A CN113491648A (zh) | 2020-04-01 | 2020-04-01 | 一种具有祛痘和祛痘印功效的精华乳及其制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202010252242.5A CN113491648A (zh) | 2020-04-01 | 2020-04-01 | 一种具有祛痘和祛痘印功效的精华乳及其制备方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN113491648A true CN113491648A (zh) | 2021-10-12 |
Family
ID=77994406
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202010252242.5A Pending CN113491648A (zh) | 2020-04-01 | 2020-04-01 | 一种具有祛痘和祛痘印功效的精华乳及其制备方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN113491648A (zh) |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200412988A (en) * | 2002-08-28 | 2004-08-01 | Nippon Shinyaku Co Ltd | Hair growth stimulants for oral use |
KR20040102558A (ko) * | 2003-05-28 | 2004-12-08 | 유앤아이화장품(주) | 차가버섯 추출물을 함유하는 피부 노화 방지용 화장료조성물 및 이의 제조방법 |
CN102228565A (zh) * | 2011-05-13 | 2011-11-02 | 潮州市泽润制药有限公司 | 一种穗花牡荆提取物的制备方法及其用途 |
CN102670469A (zh) * | 2012-06-06 | 2012-09-19 | 广州舒泰生物技术有限公司 | 一种祛痘化妆品及其制备方法 |
US20170354834A1 (en) * | 2015-08-28 | 2017-12-14 | Infinitus (China) Company Ltd. | Acne removing skin care product and preparation method thereof |
CN109431960A (zh) * | 2018-12-06 | 2019-03-08 | 广州丽彦妆生物科技有限公司 | 一种kgf祛红血丝、修复角质层冻干粉制剂及其制备方法 |
US20200078290A1 (en) * | 2016-12-15 | 2020-03-12 | Lg Household & Health Care Ltd. | Cosmetic Composition Comprising Extract Of Medicinal Herbs As Active Ingredient |
-
2020
- 2020-04-01 CN CN202010252242.5A patent/CN113491648A/zh active Pending
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200412988A (en) * | 2002-08-28 | 2004-08-01 | Nippon Shinyaku Co Ltd | Hair growth stimulants for oral use |
KR20040102558A (ko) * | 2003-05-28 | 2004-12-08 | 유앤아이화장품(주) | 차가버섯 추출물을 함유하는 피부 노화 방지용 화장료조성물 및 이의 제조방법 |
CN102228565A (zh) * | 2011-05-13 | 2011-11-02 | 潮州市泽润制药有限公司 | 一种穗花牡荆提取物的制备方法及其用途 |
CN102670469A (zh) * | 2012-06-06 | 2012-09-19 | 广州舒泰生物技术有限公司 | 一种祛痘化妆品及其制备方法 |
US20170354834A1 (en) * | 2015-08-28 | 2017-12-14 | Infinitus (China) Company Ltd. | Acne removing skin care product and preparation method thereof |
US20200078290A1 (en) * | 2016-12-15 | 2020-03-12 | Lg Household & Health Care Ltd. | Cosmetic Composition Comprising Extract Of Medicinal Herbs As Active Ingredient |
CN109431960A (zh) * | 2018-12-06 | 2019-03-08 | 广州丽彦妆生物科技有限公司 | 一种kgf祛红血丝、修复角质层冻干粉制剂及其制备方法 |
Non-Patent Citations (2)
Title |
---|
MOHANRAJ, S; VANATHI, P;: "Antimicrobial effectiveness of Vitex negundo leaf extracts", 《INDIAN JOURNAL OF FIBRE & TEXTILE RESEARCH》, vol. 4, no. 37, pages 389 - 392 * |
李春正, 苏艳芳, 靳先军: "牡荆属植物化学成分及生物活性研究进展", 中草药, no. 06, pages 930 - 938 * |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN109394585B (zh) | 一种抗氧化和保湿液晶组合物及其制备方法和应用 | |
CN107929190A (zh) | 一种舒缓抗敏面膜及制备方法 | |
CN106473944B (zh) | 一种含抗菌肽的祛痘组合物及祛痘霜 | |
CN110882186A (zh) | 一种具有控油、收缩毛孔和舒缓的组合物及其制备方法 | |
CN112426386A (zh) | 一种控油祛痘功效组合物及凝胶 | |
CN109330976A (zh) | 一种祛痘植物组合物及其制备方法 | |
CN110302121B (zh) | 一种蕴含植物精华的婴儿护臀膏及其制备方法 | |
CN108309897A (zh) | 一种芦荟保湿乳液及其制作方法 | |
US11779527B2 (en) | Useful compositions for the cosmetic treatment of oily skin | |
CN110227053A (zh) | 紧致修护眼部护理组合物及其制备和应用 | |
CN108938508A (zh) | 一种具有防晒增效作用的无花果果实提取物及其用途 | |
CN113425661A (zh) | 一种具有清洁修护功效的植物组合物及其应用 | |
JP7075177B2 (ja) | 化粧料 | |
CN113491648A (zh) | 一种具有祛痘和祛痘印功效的精华乳及其制备方法 | |
CN113491649A (zh) | 一种具有祛痘、祛痘印功效的组合物及其制备方法和用途 | |
CN109512701A (zh) | 一种预防病人褥疮的湿巾及其制备方法 | |
JP7016500B1 (ja) | 防水アイペンシル化粧品組成物及びこれを用いる防水アイペンシル化粧品の製造方法 | |
CN115003274B (zh) | 护肤组合物 | |
CN114948828A (zh) | 一种全植物无水唇釉及其制备方法 | |
KR20180091256A (ko) | 보습 효과를 증진시키는 입술용 화장료 조성물 | |
KR20140142303A (ko) | 진정 효과를 갖는 피부용 화장품 조성물 및 그 용도 | |
CN113350255A (zh) | 一种低刺激抑菌化妆品及其制备方法 | |
Rosaini et al. | Formulation of gel peel off catechins mask from gambir (Uncaria gambir (Hunter) Roxb) with the PVP K-30 concentration variation | |
Supriadi et al. | Formulation and Evaluation of Grape Seed Oil (Vitis Vinifera, L) Facial Cream with Variations in The Concentration of Stearic Acid as an Emulsifier | |
CN114668682B (zh) | 一种保湿亮肤组合物及其应用 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
TA01 | Transfer of patent application right | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20240208 Address after: Room A2-06-05, Building 1, No. 338 Huilongguan East Street, Changping District, Beijing, 100194 Applicant after: BEIJING GUOJI ZHONGFANG TRADITIONAL CHINESE MEDICINE Research Institute Country or region after: China Address before: 1105-2, floor 10, building a, yard 72, North West Third Ring Road, Haidian District, Beijing 100048 Applicant before: Beijing youyue Baishi Technology Development Co.,Ltd. Country or region before: China |