CN113425653A

CN113425653A - Preparation process of antiallergic toothpaste

Info

Publication number: CN113425653A
Application number: CN202011404060.1A
Authority: CN
Inventors: 赵新辉
Original assignee: Individual
Current assignee: Individual
Priority date: 2021-08-11
Filing date: 2021-08-11
Publication date: 2021-09-24

Abstract

The invention discloses a preparation process of antiallergic toothpaste, which comprises the following steps: the method comprises the following steps: uniformly mixing propylene glycol and lauryl sodium sulfate with deionized water or mixing the mixture I and standing for later use; step two: putting glycerol, peppermint oil, sodium dodecyl sulfate and essence into a container, and mixing and stirring to obtain a mixed solution II; step three: mixing fel bovis Seu Bubali, flos Chrysanthemi, herba splendid achnatherum, herba Micheliae Albae, herba Equiseti hiemalis, eugenol, Glycyrrhrizae radix and semen Scaphii Lychnophori at a certain proportion, extracting, purifying, simultaneously preparing herba Agkistrodon extract, and standing separately; step four: and pouring the mixed solution I and the mixed solution II into a container, adding the silver leaf extract, and uniformly mixing to obtain a mixed solution III. Has the advantages that: by mixing propylene glycol and sodium lauryl sulfate, the oral cavity cleaning device can keep the oral cavity cleaning for a long time and prolong the duration of the effect.

Description

Preparation process of antiallergic toothpaste

Technical Field

The invention relates to the field of toothpaste, in particular to a preparation process of antiallergic toothpaste.

Background

Toothpaste is a common cleaning product in daily life and has a long history. With the continuous development of science and technology, the continuous improvement and perfection of technological equipment, various types of toothpaste are developed in succession, the quality and the grade of products are continuously improved, and the existing toothpaste variety is developed into multifunctional toothpaste with complete variety, multiple functions and hundreds of brands from single clean toothpaste, so that the requirements of consumption levels of different levels are met. Gingival allergy is a common symptom of oral diseases, is called as allergic dentin or dentin allergy medically, is a sore pain symptom caused by external stimulation such as temperature, chemicals, tooth sensitive substances, mechanical action and the like of teeth, and is characterized by rapid onset, sharp pain and short time, according to Chinese patent document with publication number of CN111888313A, the disclosed antiallergic toothpaste and the preparation method thereof can remove oral peculiar smell and kill oral bacteria on the premise of having antiallergic effect, but although the antiallergic effect is provided, the duration of the antiallergic effect cannot be effectively sustained, so that the oral bacteria can be continuously proliferated, in addition, the characteristics of traditional Chinese medicinal materials are rarely utilized to provide the capability of enhancing immunity for the oral cavity in the existing toothpaste, and the existing toothpaste has the antiallergic effect but is difficult to have the quality antiallergic effect, meanwhile, the existing toothpaste has a simple preparation process, and many raw materials cannot well exert the original effect and cannot fully exert the characteristics of the raw materials.

An effective solution to the problems in the related art has not been proposed yet.

Disclosure of Invention

Aiming at the problems in the related art, the invention provides a preparation process of an antiallergic toothpaste, which aims to overcome the technical problems in the prior related art.

Therefore, the invention adopts the following specific technical scheme:

according to one aspect of the present invention, there is provided an antiallergic toothpaste.

An antiallergic toothpaste, which consists of the following raw materials in percentage by weight:

3-5% of calcium hydrophosphate, 3-7% of sodium dodecyl sulfate, 10-16% of white silver incense, 10-14% of white fel bovis seu Bubali, 5-7% of chamomile, 5-7% of splendid achnatherum, 2-4% of perlite, 5-7% of glycerol, 4-6% of essence, 5-7% of scouring rush, 8-10% of xylitol, 5-7% of licorice, 5-7% of lygodium japonicum, 3-5% of propylene glycol, 3-5% of aluminum oxide, 5-7% of silicon dioxide, 5-8% of peppermint oil, 6-10% of scaphium scaphigerum and 5-8% of eugenol.

According to another aspect of the invention, a preparation process of the antiallergic toothpaste is also provided.

The preparation process of the antiallergic toothpaste comprises the following steps:

the method comprises the following steps: uniformly mixing propylene glycol and lauryl sodium sulfate with deionized water or mixing the mixture I and standing for later use;

step two: putting glycerol, peppermint oil, sodium dodecyl sulfate and essence into a container, and mixing and stirring to obtain a mixed solution II;

step three: mixing fel bovis Seu Bubali, flos Chrysanthemi, herba splendid achnatherum, herba Micheliae Albae, herba Equiseti hiemalis, eugenol, Glycyrrhrizae radix and semen Scaphii Lychnophori at a certain proportion, extracting, purifying, simultaneously preparing herba Agkistrodon extract, and standing separately;

step four: pouring the mixed solution I and the mixed solution II into a container together, and adding the silver leaf extract and mixing uniformly to obtain a mixed solution III;

step five: putting the mixed solution III, the purified raw materials and the rest raw materials into a vacuum paste making machine together for vacuum homogenization treatment;

step six: after being uniformly mixed, degassing treatment is carried out to obtain a bright and fine paste with certain viscosity;

step seven: pouring the paste into an aluminized hose, sealing the end, and standing for 30 minutes;

step eight: completing the preparation, packaging and preparing the toothpaste.

Further, the mixing method used in the fourth step comprises the following steps:

putting the raw materials of the components into a pulverizer, pulverizing, sieving with a 50-mesh sieve, and placing into a supercritical extraction kettle, wherein the extraction temperature is 40-50 ℃, and the extraction pressure is 28-32 mPa;

performing cyclic extraction, keeping constant temperature and constant pressure for 0.5-2.5 h, and discharging at an outlet of a separator to obtain a raw material extract;

placing the extract into a stirring tank, and stirring and mixing for 10-15 min.

Further, the purification operation in the fourth step is carried out, and the raw materials are mixed and stirred; stirring, decocting in water for 2 times, each for 1 hr, mixing decoctions, filtering, concentrating the filtrate, precipitating with ethanol, standing for 12-24 hr, filtering to obtain supernatant, and concentrating to relative density of 1.20.

Further, the preparation of the silver incense extract used in the fourth step comprises: drying and crushing the bark or root bark of the silver incense, adding 70% ethanol aqueous solution with the volume being 6-12 times of the weight of the silver incense for extraction, carrying out reflux extraction at 65-75 ℃ for 2-3 times, wherein the extraction time is 1-3h each time, filtering, removing filter residues, combining filtrates, concentrating under reduced pressure to obtain an extract, and drying to obtain the silver incense extract.

Further, the degassing treatment in the sixth step is carried out for 45 to 55 minutes in vacuum until the vacuum degree reaches-1 MPa, and then the degassing is stopped.

Furthermore, the particle size of the silicon dioxide is 7-8 μm.

Furthermore, the particle size of the calcium hydrophosphate is 14-16 μm.

Further, the mass ratio of the calcium hydrophosphate to the silicon dioxide is 1: 1.5.

Furthermore, the calcium hydrophosphate and the silicon dioxide are crushed, stirred and mixed for use before preparation.

The raw material components adopted by the invention are explained as follows:

calcium hydrogen phosphate: as an enhancer (for supplementing calcium) and a swelling agent, the food can be used for biscuits and infant formula food according to the national regulations, and the maximum use amount is 1.0 g/kg; can also be used as quality modifier for fermented flour products, and can be used in a proper amount according to production requirements.

Sodium lauryl sulfate: the water-soluble cationic surfactant has the characteristics of good emulsibility, foamability, water solubility, biodegradability, alkali resistance, hard water resistance, stability in aqueous solution with wider pH value, easiness in synthesis, low price and the like, is widely applied to industries such as cosmetics, detergents, textiles, papermaking, lubrication, pharmacy, building materials, chemical engineering, oil extraction and the like, and can also be applied to basic research aspects such as the property of a positive and negative ion surfactant compound system, micelle catalysis, molecular ordered combination and the like.

Silver fragrance: the Han dynasty people take it as cold tea, which is a kind of plants in the family of Aquifoliaceae. Is evergreen shrub or arbor in subtropical zone of Aquifoliaceae. The bark is gray to gray black; the leaves are thin and leathery, oval, full-edge and glossy; small flower, yellow white and fragrant; the gynandropathic plants, usually 4-7, form a parasporal inflorescence, are axillary or grow on the current-year twigs, and have a fruit ball shape.

White ox gall: white ox gall, named as traditional Chinese medicine. The product is the whole herb of Compositae plant Chrysanthemum indicum L. Collected all the year round. The main functional indications are as follows: dispel wind, remove dampness, promote qi circulation and resolve stagnation. It can be used for treating rheumatic arthralgia, chest distress, malaria, dysentery, diarrhea, puerperal common cold, hepatitis, hemorrhoid, and scabies. Move qi and alleviate pain, open chest and relieve diaphragm, purge liver and improve vision, remove dampness and promote digestion.

And (3) chamomile: being plants of the same genus as roman chamomile, which are hormonally yellow in their efficacy, can be difficult to see in the market, since most are exported and like friends of herb tea, which can be an indispensable herb tea, and it is very common in the season of heavy winter on bald ground or in primordial regions. The stem is like asparagus, and the top is provided with a flower which is big, yellow and similar to dandelion. Leaf heart shape, located under flower. The soaking of the leaves is effective in treating common cold and cough. .

Splendid achnatherum glaucescens: moisten lung to arrest cough, diminish inflammation and alleviate pain, and heal bone. For coughing; it can be used for treating mastitis, fracture, sprain, sore, furuncle, and abscess.

Perlite: perlite is a volcano-erupted acidic lava, a vitreous rock obtained by rapidly cooling perlite, and is named because it has a pearl fracture structure. Perlite ore includes perlite, obsidian and pitchstone. The differences of the three are that the perlite has arc-shaped cracks formed due to condensation, the perlite is called a perlite structure, and the water content is 2-6%; the pitchstone has unique pitchstone luster, and the water content is 6-10%; obsidian has a glassy luster and shell-like fractures with water contents generally less than 2%.

Glycerol: colorless, odorless, and sweet viscous oily liquid. Pure glycerol is a white crystal. It melts at 17 ℃. The conventional glycerin has some moisture or impurities and thus becomes less likely to be coagulated.

Scouring rush: horsetail is sweet and bitter in taste and neutral in nature. Enters lung and liver meridians, and has effects of dispelling pathogenic wind and heat, improving eyesight, removing nebula, and stopping bleeding. Harvesting herba Equiseti hiemalis in summer, removing impurities, sun drying or shade drying, and processing: removing dead stem and residual root, spraying clear water, slightly moistening, cutting, and drying.

Xylitol: is native to Finland, and is a natural sweetener extracted from plant materials such as birch, oak, corn cob, and bagasse. In nature, xylitol is widely distributed in various fruits, vegetables and grains, but the content of xylitol is low. For human body, xylitol is not a "ship" either, and it is an intermediate of normal carbohydrate metabolism in human body.

Licorice root: the skin has different elasticity, and the surface is reddish brown or grayish brown. The root and stem are cylindrical, the surface has bud mark, and the middle of the section has marrow. Light smell, sweet and special taste. The functions are mainly used for clearing away heat and toxic material, eliminating phlegm and relieving cough, and treating abdominal cavity and the like. And (3) dry climate with long sunshine and low temperature. Licorice mostly grows in arid and semiarid desert grasslands, desert edges and loess hilly lands. The roots and rhizomes are used for medicine.

Climbing fern spore: perennial grass vines, which are 1-5 m long. The rhizomes cross, and black brown jointed hair is generated; root hair, black brown, tough and hairy. Most leaves, two types, two opposite sides of the braches on the stem, paper, and leaf axis and feather axis have loose and short hair.

Alumina: an inorganic substance, formula Al2O 3. Is a high-hardness compound, has a melting point of 2054 ℃ and a boiling point of 2980 ℃, and can be ionized at high temperature.

Silicon dioxide: the silicon atoms and oxygen atoms are arranged in long-range order to form crystalline silicon dioxide, and the short-range order or long-range disorder arrangement forms amorphous silicon dioxide. In a silicon dioxide crystal, a silicon atom is located at the center of a regular tetrahedron, four oxygen atoms are located at the four corners of the regular tetrahedron, and a plurality of such tetrahedrons are connected by oxygen atoms at the corners, each oxygen atom being common to both tetrahedrons, i.e., each oxygen atom is bonded to two silicon atoms.

Peppermint oil: is colorless or yellowish clear liquid. Has special cool fragrance, pungent taste and cool aftertaste. The color of the tea is gradually deepened after the tea is stored for a long time. Is often used for repelling mosquitoes and relieving body fatigue.

Boat-fruited sterculia seed: modern pharmacological research shows that the sterculia seed has strong inhibition effect on virus, the sterculia seed leachate has laxative effect on rabbits, the compound consisting of sterculia seed, halodendron and liquorice has strong inhibition effect on common respiratory bacteria (such as staphylococcus aureus), and has relief effect on acute diffuse fibrin exudative inflammation such as colonic mucosa congestion and edema caused by dysentery bacillus, polysaccharide is an anti-inflammatory active ingredient of sterculia seed, but can not be absorbed by intestinal tract, so the oral administration and external application effect is not good, the intraperitoneal injection effect is good, and the durian and other reports show that the sterculia seed has no obvious enhancement effect on non-specific immunity, but can enhance the functions of thymus and spleen.

Eugenol: is colorless or pale yellow liquid, has strong fragrance of clove, and is insoluble in water. The product is mainly used for resisting bacteria and reducing blood pressure; can also be used in the formula of perfume essence, various cosmetic essence and soap essence, and can also be used for preparing edible essence.

The invention has the beneficial effects that: by mixing propylene glycol and sodium dodecyl sulfate and compounding and mixing fel bovis seu Bubali, flos Matricariae Chamomillae, fructus Chlorophyti, herba Potentillae Discoloris, herba Equiseti hiemalis, eugenol, Glycyrrhrizae radix and semen Scaphii Lychnophori, good moisturizing effect and foaming effect can be provided for the preparation process and the prepared product, and the prior classification treatment of the two raw materials can ensure the full reaction of the raw materials and the improvement of the effect, and can also ensure the better fusion of auxiliary addition, in addition, the raw materials can better enhance the tooth strength through more precise treatment, eliminate the acid and pain caused by external stimulation to the teeth, the toothpaste has the functions of diminishing inflammation, cleaning and reducing the abrasion to teeth by utilizing the vacuum treatment under reasonable conditions, has better antiallergic function, and can keep the oral cavity clean for a long time and prolong the duration of the effect.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings needed in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings without creative efforts.

Fig. 1 is a flow chart of the steps of a process for preparing an anti-sensitivity toothpaste according to an embodiment of the invention.

Detailed Description

For further explanation of the various embodiments, the drawings which form a part of the disclosure and which are incorporated in and constitute a part of this specification, illustrate embodiments and, together with the description, serve to explain the principles of operation of the embodiments, and to enable others of ordinary skill in the art to understand the various embodiments and advantages of the invention, and, by reference to these figures, reference is made to the accompanying drawings, which are not to scale and wherein like reference numerals generally refer to like elements.

According to an embodiment of the invention, a process for preparing an antiallergic toothpaste is provided.

According to the embodiment of the invention, the antiallergic toothpaste comprises the following raw materials in percentage:

In order to clearly understand the technical scheme of the invention, the technical scheme of the invention is described in detail through specific examples.

The first embodiment is as follows:

3% of calcium hydrophosphate, 3% of sodium dodecyl sulfate, 12% of white silver incense, 10% of white ox gall, 5% of chamomile, 5% of splendid achnatherum, 2% of perlite, 5% of glycerol, 4% of essence, 5% of scouring rush, 8% of xylitol, 5% of liquorice, 5% of lygodium japonicum, 3% of propylene glycol, 3% of aluminum oxide, 5% of silicon dioxide, 5% of peppermint oil, 6% of scaphium scaphigerum and 5% of eugenol.

Example two:

4% of calcium hydrophosphate, 5% of sodium dodecyl sulfate, 13% of white silver incense, 12% of white ox gall, 6% of chamomile, 6% of splendid achnatherum, 3% of perlite, 6% of glycerol, 5% of essence, 6% of scouring rush, 9% of xylitol, 6% of liquorice, 6% of lygodium japonicum, 4% of propylene glycol, 4% of aluminum oxide, 6% of silicon dioxide, 6.5% of peppermint oil, 8% of scaphium scaphigerum and 6.5% of eugenol.

Example three:

5% of calcium hydrophosphate, 7% of sodium dodecyl sulfate, 16% of white silver incense, 14% of white ox gall, 7% of chamomile, 7% of splendid achnatherum, 4% of perlite, 7% of glycerol, 6% of essence, 7% of scouring rush, 10% of xylitol, 7% of liquorice, 7% of lygodium japonicum, 5% of propylene glycol, 5% of aluminum oxide, 7% of silicon dioxide, 8% of peppermint oil, 10% of scaphium scaphigerum and 8% of eugenol.

For the convenience of understanding the above technical solution of the present invention, the following detailed description is made on the flow of the above solution of the present invention with reference to the accompanying drawings, and specifically is as follows:

as shown in fig. 1, a preparation process of an antiallergic toothpaste comprises the following steps:

step S101: uniformly mixing propylene glycol and lauryl sodium sulfate with deionized water or mixing the mixture I and standing for later use;

step S103: putting glycerol, peppermint oil, sodium dodecyl sulfate and essence into a container, and mixing and stirring to obtain a mixed solution II;

step S105: mixing fel bovis Seu Bubali, flos Chrysanthemi, herba splendid achnatherum, herba Micheliae Albae, herba Equiseti hiemalis, eugenol, Glycyrrhrizae radix and semen Scaphii Lychnophori at a certain proportion, extracting, purifying, simultaneously preparing herba Agkistrodon extract, and standing separately;

step S107: pouring the mixed solution I and the mixed solution II into a container together, and adding the silver leaf extract and mixing uniformly to obtain a mixed solution III;

step S109: putting the mixed solution III, the purified raw materials and the rest raw materials into a vacuum paste making machine together for vacuum homogenization treatment;

step S111: after being uniformly mixed, degassing treatment is carried out to obtain a bright and fine paste with certain viscosity;

step S113: pouring the paste into an aluminized hose, sealing the end, and standing for 30 minutes;

step S115: completing the preparation, packaging and preparing the toothpaste.

In one embodiment, the mixing in step S107 includes the following steps:

In one embodiment, for the purification operation in step S107, the raw materials are mixed and stirred; stirring, decocting in water for 2 times, each for 1 hr, mixing decoctions, filtering, concentrating the filtrate, precipitating with ethanol, standing for 12-24 hr, filtering to obtain supernatant, and concentrating to relative density of 1.20.

In one embodiment, the preparation of the silver incense extract used in the above step S107 includes: drying and crushing the bark or root bark of the silver incense, adding 70% ethanol aqueous solution with the volume being 6-12 times of the weight of the silver incense for extraction, carrying out reflux extraction at 65-75 ℃ for 2-3 times, wherein the extraction time is 1-3h each time, filtering, removing filter residues, combining filtrates, concentrating under reduced pressure to obtain an extract, and drying to obtain the silver incense extract.

In one embodiment, the vacuum degassing for 45-55 minutes is performed for the degassing process in step S111 until the vacuum degree reaches-1 MPa, and then the process is stopped.

In one embodiment, the silica has a particle size of 7-8 μm.

In one embodiment, the calcium hydrogen phosphate has a particle size of 14-16 μm.

In one embodiment, the mass ratio of calcium hydrogen phosphate to silica is 1: 1.5.

In one embodiment, the calcium hydrogen phosphate and the silicon dioxide are pulverized, stirred and mixed before preparation.

In conclusion, by means of the technical scheme of the invention, the fel bovis seu Bubali, the chamomile, the splendid achnatherum herb, the silver incense, the scouring rush, the eugenol, the liquorice and the sterculia scaphigera are compounded and mixed for use by mixing the propylene glycol and the sodium dodecyl sulfate, so that good moisturizing effect and foaming effect can be provided for the preparation process and the prepared finished product, and the prior classification treatment of the two raw materials can ensure the full reaction of the raw materials and the improvement of the effect, and can also ensure the better fusion of auxiliary addition, in addition, the raw materials can better enhance the tooth strength through more precise treatment, eliminate the acid and pain caused by external stimulation to the teeth, the toothpaste has the functions of diminishing inflammation, cleaning and reducing the abrasion to teeth by utilizing the vacuum treatment under reasonable conditions, has better antiallergic function, and can keep the oral cavity clean for a long time and prolong the duration of the effect.

The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.

Claims

1. The antiallergic toothpaste is characterized by comprising the following raw materials in percentage by weight:

2. The antiallergic toothpaste according to claim 1, wherein the silica has a particle size of 7 to 8 μm.

3. The antiallergic toothpaste according to claim 1, wherein the calcium hydrogen phosphate has a particle size of 14 to 16 μm.

4. The antiallergic toothpaste according to claim 1, wherein the mass ratio of the calcium hydrogen phosphate to the silica is 1: 1.5.

5. The antiallergic toothpaste as claimed in claim 1, wherein the calcium hydrogen phosphate and the silica are pulverized, stirred and mixed before preparation.

6. A process for preparing an anti-sensitivity toothpaste, which is used for the anti-sensitivity toothpaste of claim 1, the process for preparing the anti-sensitivity toothpaste comprises the following steps:

step eight: completing the preparation, packaging and preparing the toothpaste.

7. The process for preparing an antiallergic toothpaste according to claim 6, wherein the mixing in the fourth step comprises the following steps:

8. The process for preparing an antiallergic toothpaste according to claim 6, wherein the purification operation in step four is carried out by mixing the above raw materials under stirring; stirring, decocting in water for 2 times, each for 1 hr, mixing decoctions, filtering, concentrating the filtrate, precipitating with ethanol, standing for 12-24 hr, filtering to obtain supernatant, and concentrating to relative density of 1.20.

9. The process for preparing an antiallergic toothpaste according to claim 6, wherein the silver incense extract used in the fourth step is prepared by: drying and crushing the bark or root bark of the silver incense, adding 70% ethanol aqueous solution with the volume being 6-12 times of the weight of the silver incense for extraction, carrying out reflux extraction at 65-75 ℃ for 2-3 times, wherein the extraction time is 1-3h each time, filtering, removing filter residues, combining filtrates, concentrating under reduced pressure to obtain an extract, and drying to obtain the silver incense extract.

10. The process for preparing an antiallergic toothpaste according to claim 6, wherein the degassing treatment in the sixth step is carried out under vacuum for 45-55 minutes until the vacuum degree reaches-1 MPa, and then the process is stopped.