CN113385491A - Method for preventing liquid hanging of sample adding needle - Google Patents
Method for preventing liquid hanging of sample adding needle Download PDFInfo
- Publication number
- CN113385491A CN113385491A CN202110665541.6A CN202110665541A CN113385491A CN 113385491 A CN113385491 A CN 113385491A CN 202110665541 A CN202110665541 A CN 202110665541A CN 113385491 A CN113385491 A CN 113385491A
- Authority
- CN
- China
- Prior art keywords
- sample adding
- pump
- adding needle
- needle
- wall
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B9/00—Cleaning hollow articles by methods or apparatus specially adapted thereto
- B08B9/02—Cleaning pipes or tubes or systems of pipes or tubes
- B08B9/023—Cleaning the external surface
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B13/00—Accessories or details of general applicability for machines or apparatus for cleaning
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B9/00—Cleaning hollow articles by methods or apparatus specially adapted thereto
- B08B9/02—Cleaning pipes or tubes or systems of pipes or tubes
- B08B9/027—Cleaning the internal surfaces; Removal of blockages
- B08B9/032—Cleaning the internal surfaces; Removal of blockages by the mechanical action of a moving fluid, e.g. by flushing
- B08B9/0321—Cleaning the internal surfaces; Removal of blockages by the mechanical action of a moving fluid, e.g. by flushing using pressurised, pulsating or purging fluid
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The embodiment of the invention provides a method for preventing a sample adding needle from being hung on liquid, and relates to the technical field of cleaning methods. The method for preventing the liquid hanging of the sample adding needle comprises the steps of extending the sample adding needle into a cleaning pool at a first preset speed, then lifting the sample adding needle at a second preset speed until the lower end of the sample adding needle is lifted to a position, located above a liquid level, at a first preset distance, and then lifting the sample adding needle at a third preset speed, so that the liquid hanging of the sample adding needle is prevented. Wherein, first speed of predetermineeing and the second speed of predetermineeing all is less than the third speed of predetermineeing, when promoting the application of sample needle promptly, adopts earlier slowly the fast mode of back to go on, can prevent effectively that the liquid phenomenon from appearing on application of sample needle surface.
Description
Technical Field
The invention relates to the technical field of cleaning methods, in particular to a method for preventing a sample adding needle from hanging liquid.
Background
In biochemical test procedures such as gene detection, it is often necessary to transfer a reagent or a sample using a sample application needle. After the loading of the loading needle is completed, in order to avoid cross contamination between different samples or reagents, the loading needle needs to be cleaned before the next sample or reagent is loaded.
However, in the prior art, after the sample adding needle is cleaned, liquid is easily remained on the surface of the sample adding needle, so that a liquid hanging phenomenon occurs, and the remained liquid can pollute the absorbed sample or reagent or influence the concentration of the sample or reagent, and further influence the test precision.
Disclosure of Invention
The invention aims to provide a method for preventing a sample adding needle from being hung on liquid, which can solve the technical problems that liquid remains on the surface of the sample adding needle after cleaning and the phenomenon of hanging liquid occurs.
Embodiments of the invention may be implemented as follows:
the embodiment of the invention provides a method for preventing a sample adding needle from hanging liquid, which comprises the steps of extending the sample adding needle into a cleaning pool at a first preset speed;
lifting the sample adding needle at a second preset speed, and lifting the sample adding needle to a position, where the lower end of the sample adding needle is located above the liquid level by a first preset distance;
lifting the sample adding needle at a third preset speed to avoid liquid hanging of the sample adding needle;
wherein the first preset speed and the second preset speed are both smaller than the third preset speed.
Optionally, before the step of lowering the sample injection needle at the first preset speed in the cleaning tank, the method for preventing the sample injection needle from hanging liquid further includes:
and cleaning the sample adding needle.
Optionally, the step of cleaning the sample adding needle includes:
the sample adding needle extends into the cleaning pool, and the lower end of the sample adding needle is positioned at the lower side of the water outlet of the cleaning pool;
starting an outer wall cleaning pump, an outer wall cleaning valve, an inner wall cleaning pump, an inner wall cleaning valve, a drain valve and a drain pump of the cleaning device to clean the inner wall and the outer wall of the sample adding needle;
and closing the drain valve and the drain pump, storing water in the cleaning pool by closing the inner wall cleaning pump or the outer wall cleaning pump, and lifting the sample adding needle to the upper edge of the cleaning pool.
Optionally, the step of extending the sample injection needle into the washing pool includes:
lowering the sample adding needle at a third preset speed until the lower end of the sample adding needle is positioned above the liquid level by the first preset distance;
and lowering the sample adding needle by a second preset distance at the first preset speed.
Optionally, the step of closing the drain valve and the drain pump and storing water in the wash tank by closing the inner wall wash pump or the outer wall wash pump comprises:
closing the outer wall washing pump, the drain valve and the drain pump to store water in the washing tank by the inner wall washing pump;
after the step of raising the sample adding needle to the upper edge of the cleaning tank, the method for preventing the sample adding needle from hanging liquid further comprises the following steps:
closing the outer wall cleaning valve in a delayed manner;
and after the outer wall cleaning valve is closed, the inner wall cleaning pump and the inner wall cleaning valve are closed in a delayed manner.
Optionally, the step of opening the outer wall washing pump, the outer wall washing valve, the inner wall washing pump, the inner wall washing valve, the drain valve, and the drain pump to wash the inner wall and the outer wall of the sample adding needle includes:
simultaneously opening the inner wall cleaning valve, the outer wall cleaning valve, the drain valve and the drain pump;
and after time delay, the inner wall cleaning pump and the outer wall cleaning pump are started simultaneously.
Optionally, in the process of cleaning the sample adding needle, the method for preventing the sample adding needle from hanging liquid further includes:
detecting whether a plunger pump arranged on the sample adding needle is positioned at a reset position or not;
if the plunger pump is located at the reset position, controlling the plunger pump to reciprocate so as to suck and discharge liquid and return to the reset position; and if the plunger pump is not located at the reset position, controlling the plunger pump to move to the reset position.
Optionally, the first preset distance is h1, and h1 is greater than or equal to 5mm and less than or equal to 10 mm.
Optionally, the value of the first preset speed is v1, and v1 is less than or equal to 20 mm/s; and/or the presence of a gas in the gas,
the value of the second preset speed is v2, and v2 is less than or equal to 20 mm/s; and/or the presence of a gas in the gas,
the value of the third preset speed is v3, and v3 is not less than 50 mm/s.
Optionally, the method for preventing the sample adding needle from hanging liquid further comprises:
and after the sample adding needle is lifted at a third preset speed, controlling a plunger pump arranged on the sample adding needle to move so as to form an air column in the sample adding needle.
The method for preventing the liquid hanging of the sample adding needle has the beneficial effects that:
the method for preventing the liquid hanging of the sample adding needle comprises the steps of extending the sample adding needle into a cleaning pool at a first preset speed, then lifting the sample adding needle at a second preset speed until the lower end of the sample adding needle is lifted to a position, located above a liquid level, at a first preset distance, and then lifting the sample adding needle at a third preset speed, so that the liquid hanging of the sample adding needle is prevented. Wherein, first speed of predetermineeing and the second speed of predetermineeing all is less than the third speed of predetermineeing, when promoting the application of sample needle promptly, adopts earlier slowly the fast mode of back to go on, can prevent effectively that the liquid phenomenon from appearing on application of sample needle surface.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings needed to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present invention and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained according to the drawings without inventive efforts.
FIG. 1 is a schematic structural diagram of a cleaning apparatus according to an embodiment of the present invention;
FIG. 2 is a schematic view of an internal structure of a cleaning apparatus according to an embodiment of the present invention;
FIG. 3 is a flowchart illustrating steps of a method for preventing a loading needle from hanging fluid according to an embodiment of the present invention;
fig. 4 is a flowchart of step S01 in the method for preventing a sample injection needle from hanging liquid according to an embodiment of the present invention.
Icon: 100-a cleaning device; 111-a washing tank; 112-a water outlet; 113-a water outlet; 114-water inlet joint; 115-a drain fitting; 121-outer wall cleaning pump; 122-outer wall purge valve; 123-inner wall cleaning pump; 124-inner wall cleaning valve; 125-plunger pump; 126-a drain valve; 127-a drain pump; 200-sample adding needle.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. The components of embodiments of the present invention generally described and illustrated in the figures herein may be arranged and designed in a wide variety of different configurations.
Thus, the following detailed description of the embodiments of the present invention, presented in the figures, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
It should be noted that: like reference numbers and letters refer to like items in the following figures, and thus, once an item is defined in one figure, it need not be further defined and explained in subsequent figures.
In the description of the present invention, it should be noted that if the terms "upper", "lower", "inside", "outside", etc. indicate an orientation or a positional relationship based on that shown in the drawings or that the product of the present invention is used as it is, this is only for convenience of description and simplification of the description, and it does not indicate or imply that the device or the element referred to must have a specific orientation, be constructed in a specific orientation, and be operated, and thus should not be construed as limiting the present invention.
Furthermore, the appearances of the terms "first," "second," and the like, if any, are used solely to distinguish one from another and are not to be construed as indicating or implying relative importance.
It should be noted that the features of the embodiments of the present invention may be combined with each other without conflict.
Fig. 1 is a schematic structural diagram of a cleaning device 100 provided in this embodiment, fig. 2 is a schematic internal structural diagram of the cleaning device 100 provided in this embodiment, and fig. 3 is a flowchart of steps of a method for preventing a loading needle from hanging liquid in this embodiment. Referring to fig. 1 to fig. 3, the present embodiment provides a method for preventing a loading probe from being hung on a liquid, which is implemented by a cleaning device 100.
The washing apparatus 100 includes a washing tank 111, an outer wall washing pump 121, an outer wall washing valve 122, an inner wall washing pump 123, an inner wall washing valve 124, a drain valve 126, and a drain pump 127. The cleaning pool 111 has a chamber for cleaning the sampling needle 200, and the two opposite sides of the chamber are provided with water outlets 112, and the lower side of the chamber is provided with a water outlet 113. The outer wall cleaning pump 121, the outer wall cleaning valve 122, and the water outlet 112 are sequentially communicated, and thus water is flushed to the cleaning tank 111 sequentially through the outer wall cleaning pump 121, the outer wall cleaning valve 122, and the water outlet 112. The cleaning of the outer wall of the sample adding needle 200 is realized through the opposite flushing of the water outlets 112 at the two sides. Specifically, a water inlet joint 114 communicated with the water outlet 112 is arranged outside the cleaning tank 111, and the outer wall cleaning valve 122 is communicated with the water inlet joint 114, so as to be communicated with the water outlet 112 through the water inlet joint 114.
The drain pump 127, the drain valve 126, and the drain port 113 are sequentially communicated, so that the water in the washing tub 111 is sequentially drained through the drain port 113, the drain valve 126, and the drain pump 127. Specifically, a drain joint 115 communicating with the drain port 113 is provided outside the washing tank 111, and a drain valve 126 communicates with the drain joint 115 to communicate with the drain port 113 through the drain joint 115.
Inner wall cleaning pump 123 and inner wall cleaning valve 124 communicate, and inner wall cleaning valve 124 communicates with application of sample needle 200 to loop through inner wall cleaning pump 123 and inner wall cleaning valve 124 and wash by water to application of sample needle 200, realize the washing of application of sample needle 200 inner wall.
The method for preventing the sample adding needle from hanging liquid provided by the embodiment is specifically explained as follows:
the method for preventing the liquid hanging of the sample adding needle provided by the embodiment comprises the following steps:
s01: the sampling needle 200 is cleaned.
The sample addition needle 200 is cleaned by the cleaning apparatus 100 described above. Fig. 4 is a flowchart of step S01 in the method for preventing the loading needle from hanging liquid provided by this embodiment. Referring to fig. 4, specifically, the step of cleaning the sampling needle 200 includes:
s11, the sample adding needle 200 is extended into the cleaning pool 111, and the lower end of the sample adding needle 200 is positioned at the lower side of the water outlet 112.
Move into washing pond 111 directly over with the application of sample needle 200 after the liquid-transfering, then descend application of sample needle 200 to inside washing pond 111, the lower extreme of application of sample needle 200 is located delivery port 112 downside simultaneously, ensures that the washing water that washes out from delivery port 112 can wash application of sample needle 200 outer wall.
Specifically, the step of lowering the sampling needle 200 into the cleaning bath 111 includes: and lowering the sample adding needle 200 at a third preset speed until the lower end of the sample adding needle is positioned at a first preset distance above the height of the liquid level, and then lowering the sample adding needle 200 at the first preset speed for a second preset distance.
Optionally, the first preset speed has a value of v1, v1 ≦ 20mm/s, and the third preset speed has a value of v3, 50mm/s ≦ v 3. Optionally, v1 ═ 5mm/s, 10mm/s, 15mm/s, or 20 mm/s; v 3-50 mm/s, 60mm/s or 70 mm/s. Optionally, the first preset distance is h1, and h1 is more than or equal to 5mm and less than or equal to 10 mm; the second preset distance is h2, and h2 is more than or equal to 35mm and less than or equal to 40 mm. Alternatively, h1 is 5mm, 8mm or 10 mm; h2 is 35mm, 38mm or 40 mm.
It should be noted that, when the cleaning step of the sampling needle 200 is performed, since the water is not stored in the cleaning tank 111 at this time, the liquid level does not exist in the cleaning tank 111 at this time, and the height of the liquid level here is the height of the liquid level formed after the water is stored in the cleaning tank 111 in the subsequent step.
S12, the outer wall washing pump 121, the outer wall washing valve 122, the inner wall washing pump 123, the inner wall washing valve 124, the drain valve 126 and the drain pump 127 are turned on.
First, the inner wall washing valve 124, the outer wall washing valve 122, the drain valve 126 and the drain pump 127 are simultaneously opened, and the inner wall washing pump 123 and the outer wall washing pump 121 are delayed to be opened, so that the washing water flows under the pumping action of the inner wall washing pump 123 and the outer wall washing pump 121, thereby simultaneously washing the inner wall and the outer wall of the sampling needle 200.
Specifically, after the inner wall washing valve 124, the outer wall washing valve 122, the drain valve 126, and the drain pump 127 are simultaneously turned on, the inner wall washing pump 123 and the outer wall washing pump 121 are turned on with a delay. The inner wall washing pump 123 and the outer wall washing pump 121 are opened with a delay of several seconds after the inner wall washing valve 124, the outer wall washing valve 122, the drain valve 126 and the drain pump 127 are opened, the inner wall washing valve 124 and the outer wall washing valve 122 are opened first for several seconds before the inner wall washing pump 123 and the outer wall washing are opened, so that the inner wall washing pump 123 and the outer wall washing pump 121 can be prevented from stalling, and the drainage is opened to prevent the washing tank from overflowing when the inner wall and the outer wall are washed. Optionally, the delay time is 1-20s here. Moreover, in the step, the pressure can reach 1-2bar before the inner wall cleaning and the outer wall cleaning are discharged, so that the high-pressure cleaning effect is realized.
S13: the external wall washing pump 121, the drain valve 126 and the drain pump 127 are closed, and the sample injection needle 200 is lifted up to the upper edge of the washing tank 111.
After the washing is finished, the inner wall washing pump 123, the drain valve 126, and the drain pump 127 are closed, and the sampling needle 200 is lifted to the upper edge of the washing well 111. It should be noted that, in the present embodiment, the upper edge of the cleaning tank 111 is at the first preset distance above the liquid level after the water is stored, that is, the position where the sampling needle 200 starts to descend at the first preset speed in step S11.
Further, in the process of performing step S01, the method for preventing the sample injection needle from hanging liquid further includes:
and detecting whether the plunger pump 125 arranged on the sample adding needle 200 is positioned at the reset position. If the plunger pump 125 is in the reset position, controlling the plunger pump 125 to reciprocate to suck and discharge liquid and return to the reset position; if the plunger pump 125 is not located at the reset position, the plunger pump 125 is controlled to move to the reset position.
Specifically, the upside of the sampling needle 200 is provided with the plunger pump 125, the plunger is driven to move relative to the sampling needle 200 through the plunger pump 125, the sampling needle 200 is controlled to suck and discharge liquid, when the plunger pump 125 is located at a reset position, the plunger is located at an initial liquid suction position, the liquid discharge in the sampling needle 200 is finished, if the plunger pump 125 is located at the reset position during detection, the plunger pump 125 is controlled to reciprocate to perform a liquid suction and discharge process, at this moment, the plunger pump 125 returns to the reset position, the samples or reagents in the sampling needle 200 are all discharged, and the cleaning is thorough. Accordingly, if the plunger pump 125 is detected not to be located at the reset position, which indicates that the sample or reagent in the sample application needle 200 may not be completely discharged, the plunger pump 125 is controlled to move to the reset position, and the sample or reagent in the sample application needle 200 can be discharged.
Optionally, a proximity switch (not shown) is further disposed at the plunger pump 125, and when the proximity switch is in the shielding state, it indicates that the plunger pump 125 moves to the reset position, so that whether the plunger pump 125 is in the reset position can be determined by whether the proximity switch is in the shielding state.
S02: the outer wall cleaning valve 122 is closed with a delay.
At the end of cleaning, the sampling needle 200 rises to the upper edge of the cleaning pool 111, and the outer wall cleaning valve 122 is closed after the outer wall cleaning pump 121 is closed for 0.2s-0.5 s. The inner wall cleaning pump 123 is closed first, and then the inner wall cleaning valve 124 is closed, so that excessive pressure is not left in the sampling needle 200 as much as possible, and thus the liquid hanging of the sampling needle 200 tip is prevented. In particular, the overpressure is a pressure greater than 1 bar.
S03: the inner wall cleaning pump 123 and the inner wall cleaning valve 124 are closed with a delay.
After the outer wall cleaning valve 122 is closed, the inner wall cleaning pump 123 and the inner wall cleaning valve 124 are closed in a delayed manner for several seconds, at this time, because the drain valve 126 and the drain pump 127 are in a closed state, the cleaning water flushed into the cleaning tank 111 from the inner wall cleaning pump 123 and the inner wall cleaning valve 124 flowing through is stored in the cleaning tank 111, so that a certain height is stored in the cleaning tank 111, at the moment, the delay time is determined according to the water storage height, and when the water storage height reaches the preset height, the inner wall cleaning pump 123 and the inner wall cleaning valve 124 can be closed.
Similarly, when the inner wall cleaning pump 123 and the inner wall cleaning valve 124 are closed, the inner wall cleaning pump 123 is closed first, and the inner wall cleaning valve 124 is closed after 0.2s to 0.5s of delay, so that the inner wall cleaning pump 123 can be prevented from rotating in a blocking manner, and the pressure of a pipeline between the inner wall cleaning pump 123 and the inner wall cleaning valve 124 is relieved.
It should be noted that, because the inner wall cleaning pump 123 has a smaller flow rate than the outer wall cleaning pump 121, and the flow rate is unstable when an excessive flow rate is stored, in this embodiment, it is preferable to first turn off the outer wall cleaning pump 121, and store water in the cleaning tank 111 through the inner wall cleaning pump 123, and it can be understood that, in other embodiments, if the flow rate of the outer wall cleaning pump 121 is appropriate, the accuracy of the water storage volume is not greatly affected, and the water storage time is not too long because of too small flow rate, the inner wall cleaning pump 123 may also be turned off first, and the water is stored in the cleaning tank 111 through the outer wall cleaning pump 121.
S04: the sample injection needle 200 is extended into the washing tank 111 at a first preset speed.
After the completion of retaining in washing pond 111, slowly stretch into washing pond 111 with application of sample needle 200, application of sample needle 200 descends with first preset speed this moment, guarantees that application of sample needle 200 exists the outer wall of remaining liquid and all submerges and wash pond 111 interior liquid level downside. The first predetermined speed is equal to the first predetermined speed.
S05: the loading needle 200 is lifted at a second preset speed, and the loading needle 200 is lifted to a position where the lower end of the loading needle 200 is located above the liquid level by a first preset distance.
S06: the loading needle 200 is lifted at a third preset speed.
When the sampling needle 200 is submerged in the liquid surface, the sampling needle 200 is lifted in a slow-first and fast-second mode. Specifically, when the loading needle 200 is lifted, the loading needle is slowly lifted according to the second preset speed, and when the loading needle is lifted to a position where the lower end of the loading needle 200 is located above the liquid level by a first preset distance, the loading needle is quickly lifted according to the third preset speed, that is, the first preset speed and the second preset speed are both smaller than the third preset speed. Through the mode of first slowly afterwards fast, reduce liquid adhesion and can effectively prevent the liquid phenomenon from appearing on sample adding needle 200 surface.
Further, the first preset distance is h1, and h1 is greater than or equal to 5mm and less than or equal to 10mm, that is, after the lower end of the loading needle 200 is lifted to a position 5-10mm above the liquid level by adopting the second preset speed, the loading needle 200 is quickly lifted by adopting the third preset speed. Optionally, h1 is 5mm, 8mm or 10 mm.
Optionally, the second preset speed has a value v2, v2 ≦ 20mm/s, optionally v2 ≦ 1mm/s, 8mm/s, 15mm/s, or 20 mm/s. Alternatively, the value of the second preset speed may be set to be equal to the value of the first preset speed.
S07: after the sample injection needle 200 is lifted at the third preset speed, the plunger pump 125 disposed on the sample injection needle 200 is controlled to move, so as to form an air column in the sample injection needle 200.
After the sample addition needle 200 is lifted up in step S06, the plunger pump 125 is controlled to move to suck the liquid into the sample addition needle 200, and at this time, since the liquid suction port at the lower end of the sample addition needle 200 is in the air, a predetermined air column is formed in the sample addition needle 200, and optionally, the volume of the air column is 15u l, so that the air column is provided above the liquid sucked into the sample addition needle 200 to close the liquid at the next liquid transfer operation.
The method for preventing the sample adding needle from hanging liquid provided by the embodiment at least has the following advantages:
according to the method for preventing the liquid hanging of the sample adding needle, after the sample adding needle 200 is cleaned, a certain amount of purified water is accumulated in the cleaning pool 111, then the sample adding needle 200 is slowly descended into the purified water in the cleaning pool 111, then the sample adding needle 200 is lifted out of the purified water in a slow-to-fast mode, and the liquid hanging phenomenon on the outer wall of the sample adding needle 200 is effectively prevented by using the adhesive force of the purified water, so that the possibility that the residual liquid on the surface of the sample adding needle 200 pollutes a reagent or a sample is avoided.
The above description is only for the specific embodiment of the present invention, but the scope of the present invention is not limited thereto, and any changes or substitutions that can be easily conceived by those skilled in the art within the technical scope of the present invention are included in the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the appended claims.
Claims (10)
1. A method for preventing a sample adding needle from hanging liquid is characterized by comprising the following steps:
the sample adding needle (200) is extended into the cleaning pool (111) at a first preset speed;
lifting the sample adding needle (200) at a second preset speed, and lifting the sample adding needle (200) to a position, at which the lower end of the sample adding needle (200) is located above the liquid level, of a first preset distance;
lifting the sample adding needle (200) at a third preset speed to avoid hanging liquid on the sample adding needle (200);
wherein the first preset speed and the second preset speed are both smaller than the third preset speed.
2. The method for preventing the hanging of the sample injection needle according to claim 1, wherein before the step of lowering the sample injection needle (200) in the washing tank (111) at the first preset speed, the method further comprises:
and cleaning the sample adding needle (200).
3. The method for preventing the hanging of the sample injection needle according to claim 2,
the step of cleaning the sample adding needle (200) comprises the following steps:
the sample adding needle (200) extends into the cleaning pool (111), and the lower end of the sample adding needle (200) is positioned at the lower side of a water outlet (112) of the cleaning pool (111);
starting an outer wall cleaning pump (121), an outer wall cleaning valve (122), an inner wall cleaning pump (123), an inner wall cleaning valve (124), a drain valve (126) and a drain pump (127) of the cleaning device to clean the inner wall and the outer wall of the sample adding needle (200);
and closing the drain valve (126) and the drain pump (127), storing water in the cleaning pool (111) by closing the inner wall cleaning pump (123) or the outer wall cleaning pump (121), and lifting the sample adding needle (200) to the upper edge of the cleaning pool (111).
4. The method for preventing the hanging of the sample adding needle according to claim 3, wherein the step of extending the sample adding needle (200) into the cleaning pool (111) comprises the following steps:
lowering the sample adding needle (200) at a third preset speed until the lower end of the sample adding needle (200) is positioned at the first preset distance above the height of the liquid level;
and lowering the sample adding needle (200) by a second preset distance at the first preset speed.
5. The method for preventing the hanging of the sample adding needle according to claim 3, wherein the step of closing the drain valve (126) and the drain pump (127) and storing water in the cleaning tank (111) by closing the inner wall cleaning pump (123) or the outer wall cleaning pump (121) comprises:
closing the outer wall washing pump (121), the drain valve (126) and the drain pump (127) to store water in the washing tank (111) by the inner wall washing pump (123);
after the step of raising the sample adding needle (200) to the upper edge of the cleaning pool (111), the method for preventing the sample adding needle from hanging liquid further comprises the following steps:
closing the outer wall cleaning valve (122) in a delayed manner;
and after the outer wall cleaning valve (122) is closed, the inner wall cleaning pump (123) and the inner wall cleaning valve (124) are closed in a delayed mode.
6. The method for preventing the hanging of the sample adding needle according to claim 3, wherein the step of opening the outer wall cleaning pump (121), the outer wall cleaning valve (122), the inner wall cleaning pump (123), the inner wall cleaning valve (124), the drain valve (126) and the drain pump (127) to clean the inner wall and the outer wall of the sample adding needle (200) comprises:
simultaneously opening the inner wall wash valve (124), the outer wall wash valve (122), the drain valve (126), and the drain pump (127);
and opening the inner wall cleaning pump (123) and the outer wall cleaning pump (121) in a delayed manner.
7. The method for preventing the hanging of the sample adding needle according to claim 2, wherein the step of cleaning the sample adding needle (200) is performed, and the method for preventing the hanging of the sample adding needle further comprises:
detecting whether a plunger pump (125) arranged on the sample adding needle (200) is positioned at a reset position or not;
if the plunger pump (125) is located at the reset position, controlling the plunger pump (125) to reciprocate so as to suck and discharge liquid and return to the reset position; and if the plunger pump (125) is not located at the reset position, controlling the plunger pump (125) to move to the reset position.
8. The method for preventing the hanging of the sample adding needle according to claim 1, wherein the first preset distance is h1, 5mm ≦ h1 ≦ 10 mm.
9. The method for preventing the hanging of the sample adding needle according to claim 1, wherein the first preset speed has a value of v1, v1 is less than or equal to 20 mm/s; and/or the presence of a gas in the gas,
the value of the second preset speed is v2, and v2 is less than or equal to 20 mm/s; and/or the presence of a gas in the gas,
the value of the third preset speed is v3, and v3 is more than or equal to 50 mm/s.
10. The method for preventing the suspension of the sample adding needle according to any one of claims 1 to 9, further comprising:
after the sampling needle (200) is lifted at a third preset speed, a plunger pump (125) arranged on the sampling needle (200) is controlled to move, so that an air column is formed in the sampling needle (200).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110665541.6A CN113385491A (en) | 2021-06-16 | 2021-06-16 | Method for preventing liquid hanging of sample adding needle |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110665541.6A CN113385491A (en) | 2021-06-16 | 2021-06-16 | Method for preventing liquid hanging of sample adding needle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN113385491A true CN113385491A (en) | 2021-09-14 |
Family
ID=77621311
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110665541.6A Pending CN113385491A (en) | 2021-06-16 | 2021-06-16 | Method for preventing liquid hanging of sample adding needle |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN113385491A (en) |
Citations (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090217951A1 (en) * | 2008-02-29 | 2009-09-03 | Ngo Dang M | Apparatus and method for cleaning a liquid handling probe |
| CN102218418A (en) * | 2010-04-14 | 2011-10-19 | 深圳迈瑞生物医疗电子股份有限公司 | Sampling needle cleaning method and device |
| CN107824564A (en) * | 2017-11-22 | 2018-03-23 | 昌微***科技(上海)有限公司 | One kind washes pin pond |
| US9964563B1 (en) * | 2014-07-18 | 2018-05-08 | Flextronics Ap, Llc | Method and apparatus for ICT fixture probe cleaning |
| CA3012304A1 (en) * | 2017-08-01 | 2019-02-01 | Tassilo Schulze | Device and method for cleaning of pipetting needles |
| CN110252741A (en) * | 2019-06-18 | 2019-09-20 | 珠海丽珠试剂股份有限公司 | Cleaning control method, the apparatus and system of sample needle |
| CN110320379A (en) * | 2018-03-30 | 2019-10-11 | 成都深迈瑞医疗电子技术研究院有限公司 | A kind of sample analyser and its cleaning method |
| CN111122896A (en) * | 2019-12-24 | 2020-05-08 | 苏州长光华医生物医学工程有限公司 | Control method and system for liquid taking process of reagent needle of medical instrument |
| CN111570422A (en) * | 2019-02-18 | 2020-08-25 | 深圳迎凯生物科技有限公司 | Sampling needle cleaning device and method |
| CN212774622U (en) * | 2020-05-13 | 2021-03-23 | 上海太阳生物技术有限公司 | Blood coagulation analyzer and plunger pump assembly thereof |
| CN112557687A (en) * | 2020-12-30 | 2021-03-26 | 珠海森龙生物科技有限公司 | Integrated liquid path control system, control method and integrated biochemical analyzer |
| CN112871885A (en) * | 2019-11-29 | 2021-06-01 | 深圳市帝迈生物技术有限公司 | Cleaning device for sample adding needle, cleaning liquid path system and method thereof, and sample analyzer |
-
2021
- 2021-06-16 CN CN202110665541.6A patent/CN113385491A/en active Pending
Patent Citations (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090217951A1 (en) * | 2008-02-29 | 2009-09-03 | Ngo Dang M | Apparatus and method for cleaning a liquid handling probe |
| CN102218418A (en) * | 2010-04-14 | 2011-10-19 | 深圳迈瑞生物医疗电子股份有限公司 | Sampling needle cleaning method and device |
| US9964563B1 (en) * | 2014-07-18 | 2018-05-08 | Flextronics Ap, Llc | Method and apparatus for ICT fixture probe cleaning |
| CA3012304A1 (en) * | 2017-08-01 | 2019-02-01 | Tassilo Schulze | Device and method for cleaning of pipetting needles |
| CN107824564A (en) * | 2017-11-22 | 2018-03-23 | 昌微***科技(上海)有限公司 | One kind washes pin pond |
| CN110320379A (en) * | 2018-03-30 | 2019-10-11 | 成都深迈瑞医疗电子技术研究院有限公司 | A kind of sample analyser and its cleaning method |
| CN111570422A (en) * | 2019-02-18 | 2020-08-25 | 深圳迎凯生物科技有限公司 | Sampling needle cleaning device and method |
| CN110252741A (en) * | 2019-06-18 | 2019-09-20 | 珠海丽珠试剂股份有限公司 | Cleaning control method, the apparatus and system of sample needle |
| CN112871885A (en) * | 2019-11-29 | 2021-06-01 | 深圳市帝迈生物技术有限公司 | Cleaning device for sample adding needle, cleaning liquid path system and method thereof, and sample analyzer |
| CN111122896A (en) * | 2019-12-24 | 2020-05-08 | 苏州长光华医生物医学工程有限公司 | Control method and system for liquid taking process of reagent needle of medical instrument |
| CN212774622U (en) * | 2020-05-13 | 2021-03-23 | 上海太阳生物技术有限公司 | Blood coagulation analyzer and plunger pump assembly thereof |
| CN112557687A (en) * | 2020-12-30 | 2021-03-26 | 珠海森龙生物科技有限公司 | Integrated liquid path control system, control method and integrated biochemical analyzer |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2676027B2 (en) | Cleaning device for needles for taking out liquid samples | |
| EP0503003B1 (en) | Apparatus and method for cleaning reagent delivery probes | |
| JPH04105066A (en) | Probe washing vessel | |
| CN110434128B (en) | Sampling needle cleaning device and cleaning method | |
| CN107435363B (en) | Urine examination urinal | |
| JP6517565B2 (en) | Dispensing nozzle cleaning method and automatic analyzer | |
| WO2015135266A1 (en) | Test strip sample pouring tank, drying analyzer and sample pouring and cleaning method thereof | |
| JP6919535B2 (en) | Dispenser | |
| CN103989448A (en) | Dishwasher and method of controlling the same | |
| CN113385491A (en) | Method for preventing liquid hanging of sample adding needle | |
| JP2001504749A (en) | Apparatus and method for cleaning pipette probe | |
| CN213728201U (en) | Cleaning tank and cleaning device | |
| JP4013202B2 (en) | Sampling tube cleaning method in blood sample sampling mechanism | |
| JP2010286420A (en) | Cleaning method of dispensing nozzle, automatic analyzer, and container | |
| JP4500081B2 (en) | Nozzle cleaning method and nozzle cleaning device | |
| JP3965043B2 (en) | Nozzle cleaning device | |
| CN205413845U (en) | Tube cleaning device with water level monitoring | |
| CN205413825U (en) | Automatic liquid belt cleaning device that annotates of test tube | |
| JP2663661B2 (en) | Liquid vacuum suction device | |
| CN113711055A (en) | Automatic analyzer | |
| CN219899466U (en) | Pipetting needle cleaning device | |
| CN112858660A (en) | Magnetic separation cleaning system and imbibition needle subassembly, immunoassay appearance thereof | |
| CN205413824U (en) | Automatic dual belt cleaning device of liquid that annotates of test tube | |
| CN218636099U (en) | Soft endoscope pretreatment device | |
| CN219842110U (en) | Detection device for high-precision detection of air tightness of cylindrical bottle body |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |