CN113376186A - High-precision intelligent erythrocyte folic acid detector and detection method thereof - Google Patents

High-precision intelligent erythrocyte folic acid detector and detection method thereof Download PDF

Info

Publication number
CN113376186A
CN113376186A CN202110514895.0A CN202110514895A CN113376186A CN 113376186 A CN113376186 A CN 113376186A CN 202110514895 A CN202110514895 A CN 202110514895A CN 113376186 A CN113376186 A CN 113376186A
Authority
CN
China
Prior art keywords
fixed mounting
folic acid
test tube
nozzle
dustcoat
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN202110514895.0A
Other languages
Chinese (zh)
Other versions
CN113376186B (en
Inventor
赵静
聂银彪
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wuxi Kejin Biotechnology Co ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN202110514895.0A priority Critical patent/CN113376186B/en
Publication of CN113376186A publication Critical patent/CN113376186A/en
Application granted granted Critical
Publication of CN113376186B publication Critical patent/CN113376186B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N23/00Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00
    • G01N23/02Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00 by transmitting the radiation through the material
    • G01N23/04Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00 by transmitting the radiation through the material and forming images of the material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N23/00Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00
    • G01N23/20Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00 by using diffraction of the radiation by the materials, e.g. for investigating crystal structure; by using scattering of the radiation by the materials, e.g. for investigating non-crystalline materials; by using reflection of the radiation by the materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The invention discloses an intelligent erythrocyte folic acid detector with high precision and a detection method thereof, and relates to the technical field of folic acid detector structures. The plasma detection device is reasonable in structure and simple in operation, the plasma to be detected is added into the reaction test tube and placed on the center frame, the detection reagent is dripped into the reaction test tube, the detection result is displayed through the display screen, the detection result can be printed through the printing port, after the detection is finished, the telescopic dropper is automatically cleaned through the cleaning mechanism, a new reaction test tube is replaced, the next detection operation can be carried out, and the purpose of improving the accuracy is achieved.

Description

High-precision intelligent erythrocyte folic acid detector and detection method thereof
Technical Field
The invention relates to the technical field of folic acid detector structures, in particular to an intelligent erythrocyte folic acid detector with high precision and a detection method thereof.
Background
Folic acid is a water-soluble vitamin, and has two modes of active absorption and diffusion passive absorption in vivo, the absorption part is mainly at the upper part of small intestine, the absorbed folic acid is stored in tissues of intestinal wall, liver, bone marrow and the like in vivo, the folic acid plays an important role in the processes of protein synthesis, cell division and growth, has a promotion effect on the formation of normal red blood cells, can reduce the generation of hemoglobin in the red blood cells and block the maturation of the cells in the absence of the folic acid, and causes megaloblastic anemia, and the detection of the folic acid of the red blood cells is mainly used for diagnosing the megaloblastic anemia.
In the prior art, a chemiluminescence method is generally used for detecting the content of erythrocyte folic acid in blood by combining a certain detection instrument, the detection instrument is generally recycled, key parts need to be cleaned after each use, the use is inconvenient, the cleaning effect of part of detectors with self-cleaning functions is poor, and the detection precision is influenced, so that an intelligent erythrocyte folic acid detector with high precision is disclosed to meet the requirements of people.
Disclosure of Invention
The invention aims to provide an intelligent erythrocyte folic acid detector with high precision and a detection method thereof, and aims to solve the problems in the background art.
In order to achieve the above purpose, the present application provides the following technical solutions: an intelligent erythrocyte folic acid detector with high precision comprises an outer cover, a bottom plate is fixedly arranged at the bottom side of the outer cover, a protective cover is fixedly arranged at the center of the top side of the bottom plate, a motor is fixedly arranged in the protective cover, a central protective cover is fixedly arranged on the top side of the protective cover, one end of an output shaft of the motor penetrates through the central protective cover and is sleeved with a central frame, the center frame is symmetrically provided with a reaction test tube and a horn-shaped tube, the top side of the bottom plate is positioned at two sides of the protective cover and is respectively and fixedly provided with a supporting column and a transmission electron microscope, a guide rail is fixedly arranged at the top side of the supporting column, a sliding block is arranged on the guide rail in a sliding way, a telescopic dropper is fixedly arranged at the top side of the sliding block through a connecting rod, the telescopic dropper is alternatively matched with the reaction test tube and the horn-shaped tube, and the transmission electron microscope corresponds to the reaction test tube.
Preferably, one side fixed mounting of horn-shaped pipe has and is used for wasing the wiper mechanism of flexible burette, one side fixed mounting of support column has the storage case, flexible burette through first hose with the storage case is linked together, one side fixed mounting of dustcoat has the charge door, the charge door pass through the pipe with the storage case is linked together.
Based on above structure, wait to detect plasma and place on the centre frame through adding in the reaction test tube, carry out relevant detection operation through operating panel, the sliding block slides on the guide rail, make flexible burette correspond with the reaction test tube, and to the reaction intraductal detection reagent that drips into, the motor makes the centre frame rotate as power output, drive the reaction test tube simultaneously and rotate, make plasma and reagent intensive mixing, observe and carry the signal through transmission electron microscope, the testing result passes through the display screen and shows, can also print the testing result through printing the mouth, detect and accomplish the back, flexible burette removes to horn shape pipe one side and rather than the looks adaptation, carry out self-cleaning through wiper mechanism to flexible burette, guarantee flexible burette department clean state, more the reaction test tube that renews, can carry out next detection operation.
Preferably, wiper mechanism includes the nozzle, the top side fixed mounting of bottom plate has support frame and water tank, nozzle slidable mounting be in one side of support frame, one side of center guard shield is located and is close to horn shape pipe position department has seted up dodges the hole, the nozzle with dodge pore phase adaptation, the top side of nozzle is equipped with actuating mechanism, one side of nozzle is in through the second hose intercommunication one side of water tank.
Furthermore, the nozzle slides on the support frame through the driving mechanism and extends to one side of the avoidance hole, the telescopic dropper corresponds to the flared tube, water in the water tank is conveyed to the nozzle through the second hose, and the water is sprayed out through the nozzle under the action of the water pump to wash the flared tube and the telescopic dropper.
Preferably, actuating mechanism includes the dwang, the dwang rotates through the pivot to be installed the top side of water tank, cup joint in the pivot and install the torsional spring, waist shape hole has been seted up to one side of dwang, the top side fixed mounting of nozzle has the dead lever, the top slidable mounting of dead lever is in waist shape is downthehole, the bottom side fixed mounting of sliding block has the driving lever, one side of driving lever with one side looks adaptation of dwang.
Further, through the setting of dwang, the sliding block is when sliding to nozzle one side, and the driving lever promotes the dwang and rotates along the pivot, and the other end drive dead lever of dwang slides in waist shape hole to make the nozzle slide along the support frame and extend to dodge downtheholely, when the sliding block slides to keeping away from nozzle one side, the torsional spring makes the nozzle reset and the roll-off dodge the hole.
Preferably, one side fixed mounting of centre frame has the permanent magnet, one side of center guard shield is located dodge hole position department fixed mounting and have the electro-magnet, the electro-magnet with one side that the permanent magnet is close to each other is opposite magnetic pole each other.
Furthermore, through the arrangement of the electromagnet, when the motor stops rotating, the electromagnet is electrified and generates magnetism, the center frame continues to rotate under the action of inertia, and when the permanent magnet and the electromagnet are close to each other, the rotation speed reduction of the center frame is finally stopped at the position where the permanent magnet is closest to the electromagnet due to the principle that the magnetic poles attract each other, so that the center frame is positioned.
Preferably, the inner side of the bottom of the central shield is of a conical structure and is provided with a water leakage hole, the water leakage hole is positioned at one side close to the electromagnet, a water receiving groove is formed in one side of the water leakage hole, a rear cover plate is rotatably installed on one side of the outer cover, and the rear cover plate is matched with the water receiving groove.
Further, the top side of center guard shield is equipped with flange structure, prevents abluent water stain wantonly sputter, through the setting of toper structure, does benefit to the drainage, and water stain flows in the water receiving tank through the hole that leaks, opens the back shroud, can take out the water receiving tank and clear up it and handle.
Preferably, one side fixed mounting cylinder that the bottom of center guard shield was kept away from the water receiving tank, the top of cylinder with the bottom side looks adaptation of reaction test tube.
Further, through the setting of cylinder, after the centre frame stall, the cylinder will react the ejecting take the altitude of test tube to be close to transmission electron microscope, do benefit to the observation, increase the image definition, improve the detection precision.
Preferably, the outer side of the telescopic dropper is sleeved with a blocking piece, the bottom side of the blocking piece is matched with the top side of the reaction test tube and corresponds to the nozzle, and the outer side of the blocking piece is matched with the inner side wall of the flared tube.
Further, through the setting of separation blade, when carrying out dropwise add detect reagent to the reaction test tube, can prevent the liquid spill, the outside of separation blade and the inside wall looks adaptation of horn-shaped pipe can make the bottom side of separation blade expose completely in the outside, makes the nozzle carry out abundant washing to it, thereby prevents to pollute and improves and detect the precision, can prevent simultaneously that water stain spill.
Preferably, one side of the outer cover is rotatably provided with an upper cover plate, one side of the upper cover plate is rotatably provided with a lower cover plate, and the outer side of the upper cover plate is matched with the outer cover and corresponds to the position of the reaction test tube.
Further, through the setting of upper cover plate and lower apron, can seal the dustcoat, prevent to have the foreign matter to get into in the testing process, influence the testing result, rotate and open upper cover plate and lower apron, be convenient for get and put the reaction test tube.
Preferably, two limiting clamping grooves are formed in the outer side of the outer cover and are respectively matched with two ends of the bottom side of the lower cover plate.
Furthermore, the upper cover plate and the lower cover plate are rotated and folded, and the two ends of the bottom side of the lower cover plate are clamped into the two limiting clamping grooves respectively, so that the lower cover plate can be kept in a stable state, the upper cover plate and the lower cover plate are prevented from falling, and the operation convenience is improved.
Preferably, a display screen and an operation panel are fixedly mounted on the top side of the outer cover, and a printing port is formed in one side of the outer cover.
Preferably, both sides of the outer cover are fixedly provided with side buckles, and one side of the lower cover plate is fixedly provided with a cover plate buckle.
Further, through the setting of side attacker, increase the hand impetus, than that and remove haulage equipment, through the setting of apron attacker, be convenient for operate and rotate upper cover plate and lower apron, through the setting of charge door, can follow outside direct injection detect reagent, increase the operation convenience.
A method for detecting folic acid in red blood cells, which is carried out by the combination of the intelligent high-precision folic acid detector for red blood cells as claimed in any one of claims 1-9.
In conclusion, the technical effects and advantages of the invention are as follows:
1. according to the invention, plasma to be detected is added into a reaction test tube and placed on a center frame, related detection operation is carried out through an operation panel, a sliding block slides on a guide rail, a telescopic dropper is enabled to correspond to the reaction test tube, a detection reagent is dripped into the reaction test tube, a motor serves as power output to enable the center frame to rotate and simultaneously drive the reaction test tube to rotate, the plasma and the reagent are fully mixed, signals are observed and transmitted through a transmission electron microscope, the detection result is displayed through a display screen, the detection result can also be printed through a printing port, after the detection is finished, the telescopic dropper is moved to one side of a horn-shaped tube and is matched with the horn-shaped tube, the telescopic dropper is automatically cleaned through a cleaning mechanism, the cleaning state of the telescopic dropper is ensured, a new reaction test tube is replaced, the next detection operation can be carried out, and the purpose of improving the accuracy is achieved.
2. According to the invention, the nozzle slides on the support frame and extends to one side of the avoidance hole through the driving mechanism, the telescopic dropper corresponds to the horn-shaped pipe, water in the water tank is conveyed to the nozzle through the second hose and is sprayed out through the nozzle under the action of the water pump to wash the horn-shaped pipe and the telescopic dropper, through the arrangement of the rotating rod, when the sliding block slides to one side of the nozzle, the shifting rod pushes the rotating rod to rotate along the rotating shaft, the other end of the rotating rod drives the fixed rod to slide in the waist-shaped hole, so that the nozzle slides along the support frame and extends into the avoidance hole, and when the sliding block slides to the side far away from the nozzle, the torsion spring enables the nozzle.
3. According to the invention, through the arrangement of the electromagnet, when the motor stops rotating, the electromagnet is electrified and generates magnetism, the center frame continues to rotate under the action of inertia, when the permanent magnet and the electromagnet are close to each other, due to the principle that magnetic poles attract each other, the rotation of the center frame is decelerated, and finally the center frame stops at the position where the permanent magnet is closest to the electromagnet, so that the center frame is positioned, the flanging structure is arranged on the top side of the center shield, the cleaning water stain is prevented from being splashed arbitrarily, through the arrangement of the conical structure, the water drainage is facilitated, the water stain flows into the water receiving tank through the water leakage holes, the rear cover plate is opened, and the water receiving tank can be taken out and cleaned.
4. According to the invention, through the arrangement of the air cylinder, after the central frame stops rotating, the air cylinder ejects the reaction test tube to a certain height, and the reaction test tube is close to the transmission electron microscope, so that the observation is facilitated, the image definition is increased, and the detection accuracy is improved.
5. According to the invention, through the arrangement of the upper cover plate and the lower cover plate, the outer cover can be sealed, foreign matters are prevented from entering in the detection process and affecting the detection result, the upper cover plate and the lower cover plate are rotated to open, the reaction test tube is convenient to take and place, the upper cover plate and the lower cover plate are rotated and folded, two ends of the bottom side of the lower cover plate are respectively clamped into the two limiting clamping grooves, the lower cover plate can be kept in a stable state, the upper cover plate and the lower cover plate are prevented from falling, the operation convenience is improved, the force application points of hands are increased through the arrangement of the side buckles, the upper cover plate and the lower cover plate are convenient to operate and rotate through the arrangement of the cover plate buckles, the detection reagent can be directly injected from the outside, and the operation convenience is improved.
Drawings
In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present application, and other drawings can be obtained by those skilled in the art without creative efforts.
FIG. 1 is a schematic perspective view of the present invention;
FIG. 2 is a schematic perspective view of another embodiment of the present invention;
FIG. 3 is a lateral side view of the present invention;
FIG. 4 is a schematic view of a partial structure of a region of a core frame according to the present invention;
FIG. 5 is a partial schematic view of the driving mechanism of the present invention;
FIG. 6 is a schematic view of a partial structure of a nozzle region according to the present invention;
FIG. 7 is a schematic view of the center shield region of the present invention;
fig. 8 is a perspective view of the folded upper cover plate of the present invention.
In the figure: 1. a housing; 2. a side handle; 3. a printing port; 4. a display screen; 5. an operation panel; 6. a limiting clamping groove; 7. an upper cover plate; 8. a lower cover plate; 9. cover plate fastener; 10. a rear cover plate; 11. a feed inlet; 12. a base plate; 13. a protective cover; 14. a motor; 15. a central shield; 16. a support frame; 17. a slider; 18. an electromagnet; 19. a transmission electron microscope; 20. a connecting rod; 21. a first hose; 22. a baffle plate; 23. a cylinder; 24. a reaction tube; 25. a center frame; 26. a telescopic dropper; 27. a horn-shaped tube; 28. a nozzle; 29. a deflector rod; 30. a guide rail; 31. a rotating shaft; 32. rotating the rod; 33. a waist-shaped hole; 34. avoiding holes; 35. fixing the rod; 36. a water receiving tank; 37. a second hose; 38. a water tank; 39. a support pillar; 40. and a permanent magnet.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example (b): referring to fig. 1-8, an intelligent high-precision red blood cell folate detector and a detection method thereof are shown, which includes a housing 1.
The bottom side fixed mounting of dustcoat 1 has bottom plate 12, and the top side central point department fixed mounting of bottom plate 12 has safety cover 13, and fixed mounting has motor 14 in the safety cover 13, and the top side fixed mounting of safety cover 13 has central guard 15, wraps up motor 14 and makes motor 14 be in encapsulated situation through safety cover 13 and central guard 15, prevents to wet impaired.
One end of an output shaft of the motor 14 penetrates through the central shield 15 and is sleeved with a central frame 25, a reaction test tube 24 and a horn-shaped tube 27 are symmetrically arranged on the central frame 25, and the motor 14 serves as power output to enable the central frame 25 to rotate and simultaneously drives the reaction test tube 24 to rotate.
Bottom plate 12's top side is located the both sides of safety cover 13 fixed mounting respectively has support column 39 and transmission electron microscope 19, the top side fixed mounting of support column 39 has guide rail 30, slidable mounting has sliding block 17 on guide rail 30, sliding block 17's top side has flexible burette 26 through connecting rod 20 fixed mounting, flexible burette 26 and reaction test tube 24 and the adaptation of horn-shaped pipe 27 in turn, add in reaction test tube 24 and wait to detect plasma, slide on guide rail 30 through sliding block 17, make flexible burette 26 correspond with reaction test tube 24, and to instiling reagent in the reaction test tube 24, after the detection is accomplished, flexible burette 26 moves and washs to horn-shaped pipe 27 one side, wrap up motor 14 and make motor 14 be in encapsulated situation through safety cover 13 and central guard 15, prevent to wet impaired.
The transmission electron microscope 19 corresponds to the reaction test tube 24, a cleaning mechanism for cleaning the telescopic dropper 26 is fixedly installed on one side of the horn 27, and the telescopic dropper 26 is cleaned by the cleaning mechanism.
One side fixed mounting of support column 39 has the storage case, flexible burette 26 is linked together with the storage case through first hose 21, the top side fixed mounting of dustcoat 1 has display screen 4 and operating panel 5, one side of dustcoat 1 is equipped with prints mouth 3, add the dress in the storage case and detect the reagent, and carry to flexible burette 26 through first hose 21, carry out relevant detection operation through operating panel 5, the testing result passes through display screen 4 and shows, can also print the result through printing mouth 3.
Based on the above structure, by adding the plasma to be detected in the reaction test tube 24 and placing it on the center frame 25, the slide block 17 slides on the guide rail 30 by the operation panel 5 to perform the relevant detection operation, so that the retractable dropper 26 corresponds to the reaction cuvette 24, and the detection reagent is dropped into the reaction test tube 24, the motor 14 is used as power output to rotate the center frame 25, simultaneously, the reaction test tube 24 is driven to rotate, so that the plasma and the reagent are fully mixed, the transmission electron microscope 19 is used for observing and transmitting signals, the detection result is displayed through the display screen 4, the detection result can be printed through the printing port 3, after the detection is finished, the telescopic dropper 26 is moved to one side of the horn-shaped tube 27 and is matched with the horn-shaped tube, the flexible dropper 26 is automatically cleaned by the cleaning mechanism, the cleaning state of the flexible dropper 26 is ensured, and a new reaction test tube 24 is replaced, so that the next detection operation can be carried out.
In this embodiment, the cleaning mechanism includes a nozzle 28, a support frame 16 and a water tank 38 are fixedly mounted on the top side of the bottom plate 12, the nozzle 28 is slidably mounted on one side of the support frame 16, an avoiding hole 34 is formed in a position, close to the flared tube 27, on one side of the central shield 15, the nozzle 28 is adapted to the avoiding hole 34, a driving mechanism is disposed on the top side of the nozzle 28, one side of the nozzle 28 is communicated with one side of the water tank 38 through a second hose 37, the nozzle 28 slides on the support frame 16 and extends to one side of the avoiding hole 34 through the driving mechanism, the telescopic dropper 26 corresponds to the flared tube 27, water in the water tank 38 is delivered to the nozzle 28 through the second hose 37, and is sprayed out through the nozzle 28 to flush the flared tube 27 and the telescopic dropper 26 under the action of the water pump.
In this embodiment, actuating mechanism includes dwang 32, dwang 32 rotates through pivot 31 and installs the top side at water tank 38, the torsional spring is installed in the cup joint on the pivot 31, waist shape hole 33 has been seted up to one side of dwang 32, the top side fixed mounting of nozzle 28 has dead lever 35, the top slidable mounting of dead lever 35 is in waist shape hole 33, the bottom side fixed mounting of sliding block 17 has driving lever 29, one side of driving lever 29 and one side looks adaptation of dwang 32, setting through dwang 32, sliding block 17 is when sliding to nozzle 28 one side, driving lever 29 promotes dwang 32 and rotates along pivot 31, the other end drive dead lever 35 of dwang 32 slides in waist shape hole 33, thereby make nozzle 28 slide and extend to dodge in hole 34 along support frame 16, when sliding block 17 slides to keeping away from nozzle 28 one side, the torsional spring makes nozzle 28 reset and the roll-off dodge hole 34.
In this embodiment, a permanent magnet 40 is fixedly mounted on one side of the center frame 25, an electromagnet 18 is fixedly mounted on one side of the center shield 15 at the position of the avoidance hole 34, opposite magnetic poles are arranged on the sides of the electromagnet 18 and the permanent magnet 40, when the motor 14 stops rotating, the electromagnet 18 is powered on and generates magnetism, the center frame 25 continues to rotate under the action of inertia, and when the permanent magnet 40 and the electromagnet 18 are close to each other, the rotation speed of the center frame 25 is finally stopped at the position where the permanent magnet 40 and the electromagnet 18 are closest to each other due to the principle that the opposite magnetic poles attract each other, so that the center frame 25 is positioned.
In this embodiment, the bottom inboard of center guard shield 15 is the toper structure and has seted up the hole that leaks, the hole that leaks is located the one side that is close to electro-magnet 18, the one side in hole that leaks is equipped with water receiving tank 36, one side of dustcoat 1 is rotated and is installed back shroud 10, back shroud 10 and 36 looks adaptations of water receiving tank, the top side of center guard shield 15 is equipped with flange structure, prevent abluent water stain wantonly to sputter, through the setting of toper structure, do benefit to the drainage, the water stain flows in water receiving tank 36 through the hole that leaks, open back shroud 10, can take out water receiving tank 36 and clear up the processing to it.
In this embodiment, one side fixed mounting cylinder 23 of water receiving tank 36 is kept away from to the bottom of center guard 15, and the top of cylinder 23 and the bottom side looks adaptation of reaction test tube 24, through the setting of cylinder 23, after centre frame 25 stall, the cylinder 23 will react the ejecting take the altitude of test tube 24 to be close to transmission electron microscope 19, do benefit to the observation, increase the image definition, improve and detect the precision.
In this embodiment, separation blade 22 is installed in the outside cup joint of flexible burette 26, separation blade 22 is corresponding with the top side looks adaptation of reaction test tube 24 and with nozzle 28 in the bottom side of separation blade 22, the outside of separation blade 22 and the inside wall looks adaptation of horn-shaped pipe 27, setting through separation blade 22, when carrying out dropwise add detect reagent to reaction test tube 24, can prevent the liquid spill, the outside of separation blade 22 and the inside wall looks adaptation of horn-shaped pipe 27, can make separation blade 22's bottom side expose completely in the outside, make nozzle 28 can carry out abundant washing to it, thereby prevent to pollute and improve and detect the precision, can prevent the water stain spill simultaneously.
In this embodiment, one side of dustcoat 1 is rotated and is installed upper cover plate 7, one side of upper cover plate 7 is rotated and is installed down apron 8, upper cover plate 7 and lower apron 8 the outside and dustcoat 1 looks adaptation and corresponding with reaction test tube 24's position, through upper cover plate 7 and lower apron 8's setting, can seal dustcoat 1, prevent to have the foreign matter to get into in the testing process, influence the testing result, rotate and open upper cover plate 7 and lower apron 8, be convenient for get and put reaction test tube 24.
In this embodiment, two limiting clamping grooves 6 are formed in the outer side of the outer cover 1, the two limiting clamping grooves 6 are respectively matched with two ends of the bottom side of the lower cover plate 8, the upper cover plate 7 and the lower cover plate 8 are rotated and folded, two ends of the bottom side of the lower cover plate 8 are respectively clamped into the two limiting clamping grooves 6, so that the lower cover plate can be kept in a stable state, the upper cover plate 7 and the lower cover plate 8 are prevented from falling, and the operation convenience is improved.
In this embodiment, the equal fixed mounting in both sides of dustcoat 1 has side attacker 2, one side fixed mounting of lower apron 8 has apron attacker 9, one side fixed mounting of dustcoat 1 has charge door 11, charge door 11 is linked together through pipe and storage case, setting through side attacker 2, increase hand impetus, compare that and remove haulage equipment, setting through apron attacker 9, be convenient for operate and rotate upper cover plate 7 and lower apron 8, setting through charge door 11, can follow outside direct injection detect reagent, increase the operation convenience.
The working principle of the invention is as follows: by adding plasma to be detected into the reaction test tube 24 and placing the plasma on the center frame 25, performing related detection operation through the operation panel 5, sliding the sliding block 17 on the guide rail 30 to enable the telescopic dropper 26 to correspond to the reaction test tube 24, dropping detection reagent into the reaction test tube 24, enabling the center frame 25 to rotate by taking the motor 14 as power output, simultaneously driving the reaction test tube 24 to rotate, enabling the plasma to be fully mixed with the reagent, observing and transmitting signals through the transmission electron microscope 19, displaying the detection result through the display screen 4, printing the detection result through the printing port 3, after the detection is completed, moving the telescopic dropper 26 to one side of the horn-shaped tube 27 to be matched with the horn-shaped tube 27, automatically cleaning the telescopic dropper 26 through a cleaning mechanism, ensuring the cleaning state of the telescopic dropper 26, replacing a new reaction test tube 24, performing next detection operation, enabling the nozzle 28 to slide on the support frame 16 and extend to one side of the avoidance hole 34 through the driving mechanism, the telescopic dropper 26 corresponds to the flared tube 27, water in the water tank 38 is conveyed to the nozzle 28 through the second hose 37, and is sprayed out through the nozzle 28 under the action of the water pump to wash the flared tube 27 and the telescopic dropper 26, through the arrangement of the rotating rod 32, when the sliding block 17 slides towards one side of the nozzle 28, the shifting rod 29 pushes the rotating rod 32 to rotate along the rotating shaft 31, the other end of the rotating rod 32 drives the fixing rod 35 to slide in the waist-shaped hole 33, so that the nozzle 28 slides along the support frame 16 and extends into the avoiding hole 34, and when the sliding block 17 slides towards one side far away from the nozzle 28, the torsion spring enables the nozzle 28 to reset and slide out of the avoiding hole 34.
Through the arrangement of the electromagnet 18, when the motor 14 stops rotating, the electromagnet 18 is electrified and generates magnetism, the center frame 25 continues rotating under the action of inertia, when the permanent magnet 40 and the electromagnet 18 are close to each other, due to the principle that magnetic poles attract each other, the rotation and deceleration of the center frame 25 are finally stopped at the position where the permanent magnet 40 and the electromagnet 18 are closest to each other, so that the center frame 25 is positioned, the top side of the center shield 15 is provided with a flanging structure to prevent washed water stains from being splashed arbitrarily, through the arrangement of the conical structure, drainage is facilitated, water stains flow into the water receiving groove 36 through water leakage holes, the rear cover plate 10 is opened, the water receiving groove 36 is taken out and cleaned, through the arrangement of the air cylinder 23, after the center frame 25 stops rotating, the air cylinder 23 ejects the reaction test tube 24 out by a certain height and is close to the transmission electron microscope 19, so that observation is facilitated, the image definition is increased, and the detection accuracy is improved, through the setting of the baffle plate 22, when the detection reagent is dripped into the reaction test tube 24, the liquid can be prevented from splashing, the outer side of the baffle plate 22 is matched with the inner side wall of the horn-shaped tube 27, the bottom side of the baffle plate 22 can be completely exposed, the nozzle 28 can fully clean the baffle plate, the pollution is prevented, the detection precision is improved, meanwhile, the water stain splashing can be prevented, through the setting of the upper cover plate 7 and the lower cover plate 8, the outer cover 1 can be closed, the foreign matter can be prevented from entering in the detection process, the detection result is influenced, the upper cover plate 7 and the lower cover plate 8 are rotated to open, the reaction test tube 24 is convenient to take and place, through rotating the upper cover plate 7 and the lower cover plate 8 and folding, the two ends of the bottom side of the lower cover plate 8 are respectively clamped into the two limit clamping grooves 6, the stable state can be kept, the upper cover plate 7 and the lower cover plate 8 are prevented from falling, the operation convenience is increased, through the setting of the side retaining hand 2, increase hand impetus, than that and remove haulage equipment, through the setting of apron attacker 9, be convenient for operate and rotate upper cover plate 7 and lower apron 8, through the setting of charge door 11, can follow the outside and directly pour into detection reagent into, increase the operation convenience.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments or portions thereof without departing from the spirit and scope of the invention.

Claims (10)

1. The utility model provides a high intelligent red blood cell folic acid detector of precision, includes dustcoat (1), its characterized in that: the bottom side fixed mounting of dustcoat (1) has bottom plate (12), the top side central point of bottom plate (12) puts fixed mounting has safety cover (13), fixed mounting has motor (14) in safety cover (13), the top side fixed mounting of safety cover (13) has central guard shield (15), the output shaft one end of motor (14) is run through central guard shield (15) and cup joints and installs center frame (25), the symmetry is equipped with reaction test tube (24) and trumpet-shaped pipe (27) on center frame (25), the top side of bottom plate (12) is located the both sides of safety cover (13) fixed mounting respectively has support column (39) and transmission electron microscope (19), the top side fixed mounting of support column (39) has guide rail (30), slidable mounting has sliding block (17) on guide rail (30), the top side of sliding block (17) has flexible burette (26) through connecting rod (20), the telescopic dropper (26) is alternatively matched with the reaction test tube (24) and the flared tube (27), and the transmission electron microscope (19) corresponds to the reaction test tube (24).
2. The high-precision intelligent erythrocyte folic acid detector according to claim 1, which is characterized in that: one side fixed mounting of horn-shaped pipe (27) has and is used for wasing the wiper mechanism of flexible burette (26), one side fixed mounting of support column (39) has the storage case, flexible burette (26) through first hose (21) with the storage case is linked together, one side fixed mounting of dustcoat (1) has charge door (11), charge door (11) through the pipe with the storage case is linked together.
3. The high-precision intelligent erythrocyte folic acid detector according to claim 2, which is characterized in that: the wiper mechanism includes nozzle (28), the top side fixed mounting of bottom plate (12) has support frame (16) and water tank (38), nozzle (28) slidable mounting be in one side of support frame (16), one side of center guard shield (15) is located and is close to avoidance hole (34) have been seted up to tubaeform pipe (27) position department, nozzle (28) with avoidance hole (34) looks adaptation, the top side of nozzle (28) is equipped with actuating mechanism, one side of nozzle (28) is in through second hose (37) intercommunication one side of water tank (38).
4. The high-precision intelligent erythrocyte folic acid detector according to claim 3, which is characterized in that: actuating mechanism includes dwang (32), dwang (32) are rotated through pivot (31) and are installed the top side of water tank (38), cup joint on pivot (31) and install the torsional spring, waist shape hole (33) have been seted up to one side of dwang (32), the top side fixed mounting of nozzle (28) has dead lever (35), the top slidable mounting of dead lever (35) is in waist shape hole (33), the bottom side fixed mounting of sliding block (17) has driving lever (29), one side of driving lever (29) with one side looks adaptation of dwang (32).
5. The high-precision intelligent erythrocyte folic acid detector according to claim 4, which is characterized in that: one side fixed mounting of centre frame (25) has permanent magnet (40), one side of center guard shield (15) is located dodge hole (34) position department fixed mounting have electro-magnet (18), electro-magnet (18) with one side that permanent magnet (40) are close to each other is opposite magnetic pole each other.
6. The high-precision intelligent erythrocyte folic acid detector according to claim 5, which is characterized in that: the bottom inboard of center guard shield (15) is the toper structure and has seted up the hole that leaks, the hole that leaks is located and is close to one side of electro-magnet (18), one side in hole that leaks is equipped with water receiving tank (36), one side of dustcoat (1) is rotated and is installed back shroud (10), back shroud (10) with water receiving tank (36) looks adaptation.
7. The high-precision intelligent erythrocyte folic acid detector according to claim 6, which is characterized in that: the bottom of the central protective cover (15) is far away from one side of the water receiving groove (36) and is fixedly provided with an air cylinder (23), and the top of the air cylinder (23) is matched with the bottom side of the reaction test tube (24).
8. The high-precision intelligent erythrocyte folic acid detector according to claim 7, which is characterized in that: the outside of flexible burette (26) is cup jointed and is installed separation blade (22), the bottom side of separation blade (22) with the top side looks adaptation of reaction test tube (24) and with nozzle (28) are corresponding, the outside of separation blade (22) with the inside wall looks adaptation of horn tube (27).
9. The high-precision intelligent instrument for detecting the folic acid of the red blood cells according to any one of the claims 1 to 8, characterized in that: one side of dustcoat (1) is rotated and is installed upper cover plate (7), one side of upper cover plate (7) is rotated and is installed down apron (8), upper cover plate (7) with the outside of apron (8) down with dustcoat (1) looks adaptation and with the position of reaction test tube (24) is corresponding, the top side fixed mounting of dustcoat (1) has display screen (4) and operating panel (5), one side of dustcoat (1) is equipped with prints mouth (3), the equal fixed mounting in both sides of dustcoat (1) has side attacker (2), one side fixed mounting of apron (8) has apron attacker (9) down, two spacing draw-in groove (6) have been seted up in the outside of dustcoat (1), two spacing draw-in groove (6) respectively with the bottom side both ends adaptation of apron (8) down.
10. A method for detecting folic acid of red blood cells is characterized in that: the detection method is completed by matching a high-precision intelligent erythrocyte folic acid detector according to any one of claims 1-9.
CN202110514895.0A 2021-05-12 2021-05-12 High-precision intelligent erythrocyte folic acid detector and detection method thereof Active CN113376186B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202110514895.0A CN113376186B (en) 2021-05-12 2021-05-12 High-precision intelligent erythrocyte folic acid detector and detection method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202110514895.0A CN113376186B (en) 2021-05-12 2021-05-12 High-precision intelligent erythrocyte folic acid detector and detection method thereof

Publications (2)

Publication Number Publication Date
CN113376186A true CN113376186A (en) 2021-09-10
CN113376186B CN113376186B (en) 2022-12-23

Family

ID=77572514

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202110514895.0A Active CN113376186B (en) 2021-05-12 2021-05-12 High-precision intelligent erythrocyte folic acid detector and detection method thereof

Country Status (1)

Country Link
CN (1) CN113376186B (en)

Citations (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101082586A (en) * 2007-07-06 2007-12-05 山东优生医疗科技有限公司 Intelligent acidum folicum detector
CN101175768A (en) * 2005-05-13 2008-05-07 夏里特柏林大学医学院 Erythropoietin variants
CN101247834A (en) * 2005-06-17 2008-08-20 生命健康科学公司 A carrier comprising one or more di and/or mono-(electron transfer agent) phosphate derivatives or complexes thereof
CN101385091A (en) * 2004-12-20 2009-03-11 全盛研究与开发公司 Radiation detectable and protective articles
CN101430330A (en) * 2008-12-17 2009-05-13 叶涛 Reagent kit for detecting blood serum folic acid concentration
CN101671722A (en) * 2009-09-28 2010-03-17 华东理工大学 Evaluation method of cell biology safety of silicon dioxide nanoparticle
CN102297857A (en) * 2011-08-05 2011-12-28 山东优生医疗科技有限公司 Intelligent red blood cell folate detector and detection method
CN105755098A (en) * 2016-03-21 2016-07-13 杭州市萧山区中医院 Combined identification method for induced differentiation of hair follicle stem cells into vascular endothelial cells
CN107603868A (en) * 2017-10-25 2018-01-19 芜湖市纯至网络科技有限公司 A kind of biotechnology gene assaying device
CN108318291A (en) * 2018-01-09 2018-07-24 成都菲斯普科技有限公司 Automatic sampling mechanism for hospital laboratory blood analysis instrument
CN109541244A (en) * 2018-10-30 2019-03-29 长沙塞克陆德医疗科技有限公司 A kind of iodine element automatic detector and its control method
WO2019206098A1 (en) * 2018-04-24 2019-10-31 深圳市帝迈生物技术有限公司 Device for automatically mixing blood sample and blood cell analysis equipment
CN210923479U (en) * 2019-11-11 2020-07-03 上海歌特维医学检验所有限公司 Rapid folic acid detection kit
CN211718254U (en) * 2020-01-17 2020-10-20 山东诺正检测有限公司 A device for folic acid detects in food
CN112058331A (en) * 2020-09-15 2020-12-11 湖南力源健康发展有限公司 Blood test tube with protect function
CN112462011A (en) * 2020-10-22 2021-03-09 安徽科博产品检测研究院有限公司 Multifunctional food detector
US20210080477A1 (en) * 2019-12-19 2021-03-18 Jiangsu Zecen Biotechnology Co., Ltd. Full-automatic chemiluminescence immunoassay analyzer
CN212872217U (en) * 2020-08-07 2021-04-02 宁波市佳溪电气有限公司 Shell assembly for immunoassay analyzer
WO2021217909A1 (en) * 2020-04-26 2021-11-04 成都斯马特科技有限公司 Chemiluminescence immunoassay analyzer
WO2022088477A1 (en) * 2020-10-27 2022-05-05 广州和实生物技术有限公司 Nucleic acid detector and nucleic acid detection method

Patent Citations (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101385091A (en) * 2004-12-20 2009-03-11 全盛研究与开发公司 Radiation detectable and protective articles
CN101175768A (en) * 2005-05-13 2008-05-07 夏里特柏林大学医学院 Erythropoietin variants
CN101247834A (en) * 2005-06-17 2008-08-20 生命健康科学公司 A carrier comprising one or more di and/or mono-(electron transfer agent) phosphate derivatives or complexes thereof
CN101082586A (en) * 2007-07-06 2007-12-05 山东优生医疗科技有限公司 Intelligent acidum folicum detector
CN101430330A (en) * 2008-12-17 2009-05-13 叶涛 Reagent kit for detecting blood serum folic acid concentration
CN101671722A (en) * 2009-09-28 2010-03-17 华东理工大学 Evaluation method of cell biology safety of silicon dioxide nanoparticle
CN102297857A (en) * 2011-08-05 2011-12-28 山东优生医疗科技有限公司 Intelligent red blood cell folate detector and detection method
CN105755098A (en) * 2016-03-21 2016-07-13 杭州市萧山区中医院 Combined identification method for induced differentiation of hair follicle stem cells into vascular endothelial cells
CN107603868A (en) * 2017-10-25 2018-01-19 芜湖市纯至网络科技有限公司 A kind of biotechnology gene assaying device
CN108318291A (en) * 2018-01-09 2018-07-24 成都菲斯普科技有限公司 Automatic sampling mechanism for hospital laboratory blood analysis instrument
WO2019206098A1 (en) * 2018-04-24 2019-10-31 深圳市帝迈生物技术有限公司 Device for automatically mixing blood sample and blood cell analysis equipment
CN109541244A (en) * 2018-10-30 2019-03-29 长沙塞克陆德医疗科技有限公司 A kind of iodine element automatic detector and its control method
CN210923479U (en) * 2019-11-11 2020-07-03 上海歌特维医学检验所有限公司 Rapid folic acid detection kit
US20210080477A1 (en) * 2019-12-19 2021-03-18 Jiangsu Zecen Biotechnology Co., Ltd. Full-automatic chemiluminescence immunoassay analyzer
CN211718254U (en) * 2020-01-17 2020-10-20 山东诺正检测有限公司 A device for folic acid detects in food
WO2021217909A1 (en) * 2020-04-26 2021-11-04 成都斯马特科技有限公司 Chemiluminescence immunoassay analyzer
CN212872217U (en) * 2020-08-07 2021-04-02 宁波市佳溪电气有限公司 Shell assembly for immunoassay analyzer
CN112058331A (en) * 2020-09-15 2020-12-11 湖南力源健康发展有限公司 Blood test tube with protect function
CN112462011A (en) * 2020-10-22 2021-03-09 安徽科博产品检测研究院有限公司 Multifunctional food detector
WO2022088477A1 (en) * 2020-10-27 2022-05-05 广州和实生物技术有限公司 Nucleic acid detector and nucleic acid detection method

Also Published As

Publication number Publication date
CN113376186B (en) 2022-12-23

Similar Documents

Publication Publication Date Title
CN103364242B (en) Full-automatic medical examination blood piece pushing and dyeing machine
CN113376186B (en) High-precision intelligent erythrocyte folic acid detector and detection method thereof
CN106841646A (en) Automatic clinical chemistry analyzer and method with spininess alternating apparatus
CN110887835B (en) Formaldehyde test box
CN208888258U (en) A kind of immune quantitative analyzer
CN110426242A (en) A kind of sampling probe
CN115326742A (en) Portable soil erosion and water loss automatic monitoring device
CN214804904U (en) Urine sampling device is used in urological department nursing
CN214472784U (en) Integrated cleaning and measuring device and chemiluminescence immunoassay analyzer
CN114778535A (en) High-accuracy biochemical analyzer
CN206804401U (en) Sample Riker mount
CN209640023U (en) A kind of sampler for neutral aqueous ink experiment
CN209387341U (en) A kind of sampler of coal chemical industry water environment detection
CN216880905U (en) Novel device of automatic sampler of dissolution instrument
CN217621360U (en) Mixing arrangement for dry powder mortar
CN216154307U (en) Immunochromatographic kit with shaking-up function
CN205879966U (en) Anionic surface active agent autoanalysis device
CN218330835U (en) Extraction device for food nutrition detection
CN202794192U (en) Excrement sediment specimen detecting and sampling instrument
CN219518847U (en) Solution reaction box for measuring DPPH free radical scavenging efficiency
CN220829462U (en) Device for detecting heavy metals and microelements in soil
CN218035993U (en) Proportioning device for determining concentration of sophora flower bud crude polysaccharide solution
CN215297127U (en) Full-automatic biochemical analyzer capable of observing and monitoring in whole course
CN216171520U (en) Liquid soap blending device capable of accelerating reaction
CN209525177U (en) A kind of automatic blood evenly mixing device

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
TA01 Transfer of patent application right
TA01 Transfer of patent application right

Effective date of registration: 20221206

Address after: No. 15, South Houshan Road, New Century Industrial Park, Anzhen Street, Xishan District, Wuxi City, Jiangsu Province, 214101

Applicant after: Wuxi Kejin Biotechnology Co.,Ltd.

Address before: 7575 Daye Road, Fengcheng Town, Fengxian District, Shanghai, 200000

Applicant before: Zhao Jing

GR01 Patent grant
GR01 Patent grant