CN113368225A - Compound prescription for treating diabetes and three highs - Google Patents

Compound prescription for treating diabetes and three highs Download PDF

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Publication number
CN113368225A
CN113368225A CN202110763131.5A CN202110763131A CN113368225A CN 113368225 A CN113368225 A CN 113368225A CN 202110763131 A CN202110763131 A CN 202110763131A CN 113368225 A CN113368225 A CN 113368225A
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CN
China
Prior art keywords
prescription
radix
rhizoma
treating diabetes
recipe
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CN202110763131.5A
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Chinese (zh)
Inventor
徐庆恒
淡学双
周福双
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Sichuan Shuangpeng Health Technology Co ltd
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Sichuan Shuangpeng Health Technology Co ltd
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Priority to CN202110763131.5A priority Critical patent/CN113368225A/en
Publication of CN113368225A publication Critical patent/CN113368225A/en
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K31/733Fructosans, e.g. inulin
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Abstract

The invention discloses a compound prescription for treating diabetes and hypertension, hyperlipidemia and hyperglycemia, which consists of a main prescription and a supplement prescription, wherein the supplement prescription consists of earthworm protein, nattokinase, lumbrokinase, hirudin, inulin, red yeast rice, sunflower disc small molecular peptide, edible selenium powder and glutathione. The invention mainly adopts a main formula and a correction formula to realize the effective prevention and treatment of three highs by combining Chinese and western medicines, has obvious treatment effect, combines the pathogenesis and pathology of the three highs, can realize the treatment of both principal and secondary aspect of disease, and can be matched with a dietary therapy auxiliary formula and a vitamin auxiliary formula to improve the immunity of human bodies and strengthen the treatment effect.

Description

Compound prescription for treating diabetes and three highs
Technical Field
The invention relates to the technical field of medicines, in particular to a compound prescription for treating diabetes and hypertension, hyperlipidemia and hyperglycemia.
Background
Three highs refer to hyperlipidemia, hypertension and hyperglycemia, wherein serious hyperglycemia can cause diabetes. The main causes of the three high diseases are due to long-time diet problems, such as excessive lipid and excessive alcohol in the diet, and the lipid alcohol substances in the body are gradually increased because reasonable exercise is not performed to promote the metabolism of the lipid alcohol; the substances are mixed in blood to block capillary vessels, and the lipid-alcohol substances are easily combined with free mineral ions in the body to form thrombus with the lapse of time; thrombus is easy to accumulate and calcify at the corners or the bottle necks of the blood vessels; meanwhile, the thrombus is more and more, so that the diameter of the blood vessel is reduced; in order to maintain a sufficient blood supply to the heart, the blood pressure is increased, causing hypertensive diseases; it may also be caused by excessive smoking or excessive drinking, impairment of the spleen and stomach, dysfunction of the spleen in transportation, and failure of the diet to normalize.
Disclosure of Invention
Therefore, based on the above background, the present invention provides a compound formulation for treating diabetes and hypertension, which can be used for treating hyperlipidemia, hyperglycemia, hypertension, etc., has excellent therapeutic effects on insulin-dependent diabetes and non-insulin-dependent diabetes, and has excellent effects of lowering blood sugar and urine sugar, strengthening body constitution, and increasing body weight.
The technical scheme of the invention is as follows:
a compound prescription for treating diabetes and three highs consists of a main prescription and a supplement prescription, wherein the main prescription is prepared from the following raw materials:
radix astragali, rhizoma Polygonati, Coptidis rhizoma, Ginseng radix Rubri, radix scrophulariae, Saviae Miltiorrhizae radix, rhizoma Dioscoreae, pollen, radix Puerariae, fructus Alpinae Oxyphyllae, semen plantaginis, rhizoma Atractylodis, cimicifugae rhizoma, bupleuri radix, pericarpium Citri Tangerinae, Poria, Atractylodis rhizoma, and Glycyrrhrizae radix;
the prescription is prepared from the following raw materials:
earthworm protein, nattokinase, lumbrokinase, hirudin, inulin, red yeast rice, sunflower disc small molecular peptide, edible selenium powder and glutathione.
Further, the dosage of each raw material of the main formula is as follows:
120-360 g of astragalus mongholicus, 120-360 g of rhizoma polygonati, 20-60 g of coptis chinensis, 60-180 g of red ginseng, 120-360 g of radix scrophulariae, 120-360 g of salvia miltiorrhiza, 120-360 g of raw Chinese yam, 120-360 g of raw pollen, 40-120 g of radix puerariae, 20-60 g of sharpleaf galangal fruit, 10-30 g of semen plantaginis, 20-60 g of rhizoma atractylodis, 20-60 g of rhizoma cimicifugae, 20-60 g of radix bupleuri, 20-60 g of pericarpium citri reticulatae, 20-60 g of poria cocos, 20-60 g of rhizoma atractylodis macrocephalae and 10-30 g of liquorice;
further, the food therapy auxiliary formula comprises the following raw materials in parts by weight: 100 g of peanut, medlar, red date, gordon euryale seed, ginger and astragalus root respectively.
Furthermore, the vitamin auxiliary formula also comprises vitamin B group vitamins, folic acid, mercurial-preserving honeysuckle tablets and dried yeast tablets.
Furthermore, the main formula of the invention can be prepared into any conventional oral administration dosage form by adopting a conventional method of a traditional Chinese medicine preparation.
Furthermore, various conventional auxiliary materials required for preparing different dosage forms can be added into the main formula of the invention to prepare any common oral dosage form, such as: pill, powder, tablet, capsule, oral preparation, etc.
In the main part of the invention: the astragalus membranaceus is sweet in taste and warm in nature, enters lung and spleen channels, and has the effects of tonifying qi, consolidating superficial resistance, promoting urination, expelling toxin, expelling pus, healing sores, promoting granulation and the like; rhizoma polygonati is sweet in taste and neutral in nature, and has the effects of tonifying qi and yin, strengthening spleen, moistening lung, tonifying kidney and the like, and the rhizoma polygonati enters spleen channels, lung channels and kidney channels; the coptis chinensis is bitter in taste and cold in nature, and has the effects of clearing heat, drying dampness, purging fire, detoxifying and the like, and the coptis chinensis is responsible for heart, spleen, stomach, liver, gallbladder and large intestine channels; the red ginseng is sweet in taste, slightly bitter in taste and warm in nature, has the effects of invigorating primordial qi, recovering pulse, relieving depletion, benefiting qi, controlling blood and the like, and is used for invigorating spleen, lung and heart channels; radix scrophulariae is sweet and bitter in taste and slightly cold in nature, enters lung, stomach and kidney channels, and has the effects of cooling blood, nourishing yin, purging pathogenic fire, removing toxicity and the like; the salvia miltiorrhiza, which is bitter in taste and slightly cold in nature, enters heart and liver channels and has the effects of removing blood stasis, relieving pain, activating blood circulation, stimulating the menstrual flow, clearing away heart fire, relieving restlessness and the like; the Chinese yam is sweet in taste and neutral in nature, has the functions of tonifying spleen, nourishing stomach, promoting the production of body fluid, benefiting lung, tonifying kidney, arresting seminal emission and the like, and enters spleen, lung and kidney channels; the pollen is sweet, sour and cold in taste, and has the effects of clearing heat, relieving restlessness, promoting the production of body fluid, quenching thirst and the like; the kudzu vine root is sweet and pungent in taste and cool in nature, and has the effects of relieving muscles and reducing fever, promoting the production of body fluid, promoting eruption, invigorating yang, stopping diarrhea and the like, and the spleen and stomach channels are reached; fructus alpiniae oxyphyllae, pungent in taste, warm in nature, and capable of entering spleen and kidney meridians, and has the effects of warming spleen, warming kidney, strengthening qi, arresting seminal emission and the like; the plantain seed is sweet in taste and slightly cold in nature, enters liver, kidney, lung and small intestine channels, and has the effects of clearing heat, promoting urination, excreting dampness, treating stranguria, improving eyesight and the like; the rhizoma atractylodis is pungent and bitter in taste and warm in nature, enters spleen, stomach and liver channels, and has the effects of eliminating dampness, strengthening spleen, dispelling wind and cold, improving eyesight and the like; cimicifugae rhizoma, pungent and slightly sweet in taste, slightly cold in nature, enters lung, spleen, stomach and large intestine channels, and has the effects of relieving exterior syndrome, promoting eruption, clearing heat and detoxicating, and lifting yang qi; the radix bupleuri is bitter in taste and slightly cold in nature, enters liver and gallbladder channels, and has the effects of harmonizing exterior and interior, soothing liver, invigorating yang and the like; the dried orange peel is bitter and pungent in taste and warm in nature, enters lung and spleen channels, and has the effects of regulating qi, strengthening spleen, eliminating dampness and phlegm and the like; poria cocos is sweet and light in flavor, has mild nature, has effects of benefiting heart, lung, spleen and kidney channels, promoting diuresis, eliminating dampness, invigorating spleen and calming heart; the bighead atractylodes rhizome is bitter and sweet in taste and warm in nature, enters spleen and stomach channels, and has the effects of strengthening spleen and tonifying qi, eliminating dampness and promoting diuresis, arresting sweating and the like; the liquorice has sweet taste and mild nature, enters heart, lung, spleen and stomach channels, and has the effects of tonifying spleen and qi, clearing heat and detoxicating, eliminating phlegm and stopping cough, relieving spasm and pain, harmonizing the drugs and the like.
In the correction of the present invention, the correction is performed,
the Lumbricus protein has effects of improving microcirculation, dissolving fresh and old thrombi, promoting capillary vessel regeneration, softening blood vessel, reducing blood viscosity, regulating blood pressure, and reducing blood sugar, and can be used for treating hemiplegia, thrombi type diseases, cardiovascular disease and cerebrovascular disease, and also has anti-tumor effect;
nattokinase has effects of dissolving thrombus, reducing blood viscosity, improving blood circulation, softening and increasing blood vessel elasticity, and its thrombolysis speed is 19 times of that of urokinase. It has obvious effect on treating ischemic cerebral apoplexy, can inhibit platelet coagulation, and has positive effects on preventing and treating cardiovascular and cerebrovascular embolism and embolic senile dementia;
the lumbrokinase has special affinity with thrombus (fibrin), can track thrombolysis, effectively dissolve thrombus, improve microcirculation, strengthen collateral circulation of cerebral vessels, openly repair damaged endothelial cells of blood vessels, increase elasticity of blood vessels, improve oxygen supply function of blood vessels, reduce blood viscosity, reduce platelet aggregation rate, and inhibit thrombus from forming again. It can repair necrotic brain cells around after thrombosis, save half dark space, and can be used for treating diseases of heart, cerebral vessels, endocrine, respiratory system, etc.;
hirudin has anticoagulant and antithrombotic polypeptide substances, can inhibit platelet aggregation, blood cell depolymerization and thrombus dissipation, promote microcirculation, eliminate fatty liver, eliminate atherosclerosis, activate thrombolytic function of human body, and has effects of reducing blood lipid, improving hemorheology, resisting tumor, and treating multiple thrombosis diseases, and preventing apoplexy and secondary apoplexy.
Inulin has effects of controlling blood lipid, lowering blood sugar, regulating intestinal canal microbial flora, inhibiting composition of toxic fermentation product, promoting mineral absorption, protecting liver, preventing constipation and treating obesity, and can be used for ischemic arterial embolism.
The red yeast rice is sweet in taste, warm in nature and free of toxicity, belongs to liver, spleen and large intestine channels, and has the effects of promoting blood circulation to remove blood stasis, invigorating spleen to promote digestion, reducing blood fat, reducing blood pressure, reducing cholesterol and triglyceride, enhancing human immunity and the like.
The sunflower disc small molecular peptide has the effects of expanding blood vessels and softening blood vessels, can effectively reduce the cholesterol content in serum, plays a role in purifying blood, and has a good protection effect on cardiovascular and cerebrovascular diseases.
The selenium element in the edible selenium powder has the functions of improving the immunity of human bodies, eliminating free radicals, protecting optic nerves, protecting the liver and the heart and preventing toxic substances from being generated in the human bodies.
Glutathione, which consists of glutamic acid, cysteine and glycine, is present in almost every cell of the body, helps to maintain normal immune system function, and has antioxidant and antidotal effects. Glutathione acts as an important antioxidant and free radical scavenger in the body. It is combined with free radical, heavy metal, etc. to convert harmful matter into harmless matter and eliminate it from body.
Selenium acts in combination with glutathione to eliminate free radicals (meaning substances that are unpaired by electrons and that are detrimental to cell membranes, DNA, proteins and molecules of overall cellular structure and function) and protect the health of the cell. Glutathione itself is easily depleted and therefore needs to be replenished continuously and in a timely manner. Too low a glutathione content in the human body can lead to inflammation, toxicity, etc., and loss of synaptic support components, etc. Severe patients also induce the development of cognitive decline in the brain and senile dementia. Selenium plays a critical role in the remodeling process after glutathione scavenges free radicals.
The invention can be used for treating hypertension, hyperglycemia and hyperlipidemia, has obvious curative effect on non-insulin-dependent diabetes mellitus and insulin-dependent diabetes mellitus, particularly the main formula, adopts the mutual cooperation of the traditional Chinese medicines to tonify qi and yin, purge dryness-heat hyperactivity and improve the immunity of the organism, and leads the traditional Chinese medicines to play the synergistic effects of nourishing yin and tonifying qi, strengthening spleen and tonifying kidney, promoting the production of body fluid to quench thirst, moistening dryness and relieving restlessness so as to achieve the purpose of adjusting the balance of yin and yang of the upper, middle and lower triple energizer of viscera. Restoring the sensitivity of the tissue of the body affected by the inflammation to insulin. Repairing damaged internal organs. After the viscera are well regulated, the carbohydrate absorbed every day can be fully transferred into the cells of the human body and converted into the nutrition and energy of each organ of the human body after being converted into glucose. Glucose can be delivered into cells only after the viscera are conditioned. Diabetes can really improve and recover, and complications can really disappear.
Compared with the prior art, the invention has the advantages that:
the invention mainly adopts a main formula and a correction formula to realize the effective prevention and treatment of three highs by combining Chinese and western medicines, has obvious treatment effect, combines the pathogenesis and pathology of the three highs, can realize the treatment of both principal and secondary aspect of disease, and can be matched with a dietary therapy auxiliary formula and a vitamin auxiliary formula to improve the immunity of human bodies and strengthen the treatment effect.
Detailed Description
The present invention is further described below with reference to specific embodiments, and it should be noted that, without conflict, any combination between the embodiments or technical features described below may form a new embodiment.
Example 1: a compound prescription for treating diabetes and three highs consists of a main prescription and a correction prescription, wherein the main prescription comprises the following raw materials in parts by weight:
120 g of astragalus, 120 g of rhizoma polygonati, 20g of coptis, 60 g of red ginseng, 120 g of radix scrophulariae, 120 g of salvia miltiorrhiza, 120 g of raw Chinese yam, 120 g of raw pollen, 40 g of radix puerariae, 20g of fructus alpiniae oxyphyllae, 10g of semen plantaginis, 20g of rhizoma atractylodis, 20g of rhizoma cimicifugae, 20g of radix bupleuri, 20g of pericarpium citri reticulatae, 20g of poria cocos, 20g of rhizoma atractylodis macrocephalae and 10g of liquorice;
the prescription is prepared from the following raw materials:
earthworm protein, nattokinase, lumbrokinase, hirudin, inulin, red yeast rice, sunflower disc small molecular peptide, edible selenium powder and glutathione.
The food therapy auxiliary formula also comprises a food therapy auxiliary formula and a vitamin auxiliary formula, wherein the food therapy auxiliary formula is prepared from the following raw materials in parts by weight: 100 g of peanut, medlar, red date, gordon euryale seed, ginger and astragalus root respectively;
the vitamin auxiliary formula consists of B vitamins, folic acid, mercurial-preserving silver tablets and dried yeast tablets.
Example 2: a compound prescription for treating diabetes and three highs consists of a main prescription and a correction prescription, wherein the main prescription comprises the following raw materials in parts by weight:
360 g of astragalus, 360 g of rhizoma polygonati, 60 g of coptis, 180 g of red ginseng, 360 g of radix scrophulariae, 360 g of salvia miltiorrhiza, 360 g of raw Chinese yam, 360 g of raw pollen, 120 g of radix puerariae, 60 g of fructus alpiniae oxyphyllae, 30 g of semen plantaginis, 60 g of rhizoma atractylodis, 60 g of rhizoma cimicifugae, 60 g of radix bupleuri, 60 g of pericarpium citri reticulatae, 60 g of poria cocos, 60 g of rhizoma atractylodis macrocephalae and 30 g of liquorice;
the prescription is prepared from the following raw materials:
earthworm protein, nattokinase, lumbrokinase, hirudin, inulin, red yeast rice, sunflower disc small molecular peptide, edible selenium powder and glutathione.
The food therapy auxiliary formula also comprises a food therapy auxiliary formula and a vitamin auxiliary formula, wherein the food therapy auxiliary formula is prepared from the following raw materials in parts by weight: 100 g of peanut, medlar, red date, gordon euryale seed, ginger and astragalus root respectively;
the vitamin auxiliary formula consists of B vitamins, folic acid, mercurial-preserving silver tablets and dried yeast tablets.
The food therapy auxiliary formula of the embodiment 1 and the embodiment 2 has the eating mode that the raw materials are mixed and then are stewed by adopting a pressure cooker, and then the food therapy auxiliary formula is eaten instead of breakfast.
The main formula of the embodiment 1 and the embodiment 2 can be prepared into decoction, powder or capsule for administration.
The components of the vitamin auxiliary formula can be taken according to the conventional dosage.
Example 3: typical cases
Wangzhi, man, 76 years old, Shandong tobacco Tairen, who saw a doctor in 11 months and 01 days in 2020, who had diabetes and hypertension for more than twenty years, took orally hypoglycemic western medicines: xiaotangning, pioglitazone hydrochloride, a blood pressure lowering western medicine metformin and a kidney tonifying and pulse invigorating capsule. Due to high blood pressure and the like, the heart is not good enough, sinus bradycardia and arrhythmia also exist in the neck arterial plaque. The long-term administration of hypotensor can be controlled at 110/65 (after western medicine is taken). There is a smoking and drinking preference.
In the afternoon of 10 months and 1 day in 2020, the patient feels dizzy and falls down dangerously. After the family holds the person, the left leg cannot walk well in the forward walking process, and the person feels like stepping on cotton. The right leg is strong. The patient is sent to the hospital and is taken with western medicines, etc., the current situation is maintained, no improvement is found, and the patient is returned to the home and is in bed for rest.
The tongue coating is observed in 1 st 11 th month in 2020, and is white, thick and greasy, and belongs to phlegm-dampness, yang deficiency and qi deficiency, and the veins in the sublingual Jinjin and Yuye are irritated and become purple. Diagnosing the thrombus and the serious blockage of the artery and the vein in the body. Through comprehensive diagnosis, the disease belongs to the diabetes mellitus of phlegm dampness, qi deficiency, yang deficiency and blood stasis, and the three-high syndrome.
The preparation is used for treatment in embodiment 2 of the invention, a dietotherapy auxiliary formula is used for replacing breakfast in the treatment process, the vitamin auxiliary formula is taken according to the conventional method, the main formula in embodiment 1 is taken, one dose is taken every day, after 7 doses of the main formula are taken, the supplementation is started, a patient takes about 20g of the preparation per day, after ten days, the dose is reduced to about 10g per day, and the preparation is taken under the tongue once. The main formula is continuously taken while the correction is taken.
After twenty days of treatment, the patient obviously changes that the defecation quantity is obviously reduced, the fury veins at the sublingual Jinjin jade liquid are disappeared, the color of the veins becomes light, the head is not dizzy before twenty days, and the left leg is forceful and does not float.
3, 7 and 5, 26 in 2021, the body of the old improves, symptoms disappear completely, the body recovers to a normal state, and the blood pressure and the blood sugar are only slightly higher than normal values but within a reasonable range.
The invention and its embodiments have been described above, without this being limitative. In summary, those skilled in the art should appreciate that they can readily use the disclosed conception and specific embodiments as a basis for designing or modifying other structures for carrying out the same purposes of the present invention without departing from the spirit and scope of the invention as defined by the appended claims.

Claims (4)

1. The compound prescription for treating diabetes and three highs is characterized by comprising a main prescription and a supplement prescription, wherein the main prescription is prepared from the following raw materials:
radix astragali, rhizoma Polygonati, Coptidis rhizoma, Ginseng radix Rubri, radix scrophulariae, Saviae Miltiorrhizae radix, rhizoma Dioscoreae, pollen, radix Puerariae, fructus Alpinae Oxyphyllae, semen plantaginis, rhizoma Atractylodis, cimicifugae rhizoma, bupleuri radix, pericarpium Citri Tangerinae, Poria, Atractylodis rhizoma, and Glycyrrhrizae radix;
the prescription is prepared from the following raw materials:
earthworm protein, nattokinase, lumbrokinase, hirudin, inulin, red yeast rice, sunflower disc small molecular peptide, edible selenium powder and glutathione.
2. The compound prescription for treating diabetes and hypertension, hyperglycemia and hyperlipidemia according to claim 1, wherein the dosage of each raw material of the main prescription is as follows:
360 g of astragalus mongholicus, 360 g of rhizoma polygonati, 20-60 g of coptis chinensis, 60-180 g of red ginseng, 360 g of radix scrophulariae, 120 g of salvia miltiorrhiza, 360 g of raw Chinese yam, 120 g of raw pollen, 40-120 g of radix puerariae, 20-60 g of sharpleaf galangal fruit, 10-30 g of plantain seed, 20-60 g of rhizoma atractylodis, 20-60 g of rhizoma cimicifugae, 20-60 g of radix bupleuri, 20-60 g of pericarpium citri reticulatae, 20-60 g of poria cocos, 20-60 g of rhizoma atractylodis macrocephalae and 10-30 g of liquorice.
3. The compound recipe for treating diabetes and hypertension, according to claim 1 or 2, characterized by further comprising a dietetic assistant recipe, wherein the dietetic assistant recipe is prepared from the following raw materials by weight: 100 g of peanut, medlar, red date, gordon euryale seed, ginger and astragalus root respectively.
4. The compound recipe for treating diabetes and hypertension, hyperlipidemia and hyperglycemia as claimed in any one of claims 1 to 3, further comprising a vitamin assistant recipe, wherein the vitamin assistant recipe consists of B vitamins, folic acid, LIANGCHUNYIN tablet, and dried yeast tablet.
CN202110763131.5A 2021-07-06 2021-07-06 Compound prescription for treating diabetes and three highs Withdrawn CN113368225A (en)

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