CN113318019A - Acne-removing gel composition containing various plant essences - Google Patents

Acne-removing gel composition containing various plant essences Download PDF

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CN113318019A
CN113318019A CN202110511763.2A CN202110511763A CN113318019A CN 113318019 A CN113318019 A CN 113318019A CN 202110511763 A CN202110511763 A CN 202110511763A CN 113318019 A CN113318019 A CN 113318019A
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acne
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李继国
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Nanjing Miaobang Meiye Enterprise Management Co ltd
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Abstract

The invention relates to the technical field of cosmetics, and relates to an acne-removing gel composition containing various plant essences, which comprises the following components in parts by weight: nicotinamide, witch hazel extract, lactobacillus/pear juice fermentation product filtrate, barberry bark extract, white willow leaf extract, chinese viola root extract, neem leaf extract, scutellaria root extract, houttuynia cordata extract, glycine max seed extract, wild chrysanthemum flower extract, dandelion extract, hypericum perforatum extract, honeysuckle flower extract, Chinese violet extract, purslane extract, and the like. The raw materials of the invention contain various plant extraction components and other functional components, which can not only help to relieve acne inflammation, but also inhibit excessive secretion of facial sebaceous glands and accelerate skin metabolism, and in addition, the invention also adds high moisture-preserving components of multiple hyaluronic acid essences, so that the skin after use is moist, soft and not tight.

Description

Acne-removing gel composition containing various plant essences
Technical Field
The invention relates to the technical field of cosmetics, and particularly relates to an acne-removing gel composition containing various plant essences.
Background
With the increasing trend of dietary habits towards the more prominent phenomenon of high lipidization caused by the improvement of living standard, acne, namely common acne, is more and more widely covered by people, namely not only adolescents in adolescence, but also a plurality of people after 80 and 90. Statistically, one community-based study found that the incidence of acne was 8.1% in the chinese population, and another study showed that about 41% of college students developed acne. In addition, scars are left in 3-7% of patients with acne, and a large physical and psychological health burden is caused to the patients.
The main treatments for acne conditions currently on the market are the following three: firstly, health-care food or medicine for removing acne by oral administration, such as antibiotics, isotretinoin and the like; secondly, applying ointment for removing acne, such as adapalene; and thirdly, applying skin care products for removing acne, such as creams, application type masks and the like. For the first method, the treatment course is long, the dosage is not easy to control, and the skin is easy to generate drug resistance; for the second method, the irritation to the skin is large, and the side effect is large; with respect to the third method, acne-removing products are available in the market in a large number of categories, and the skin feel and actual effect are not uniform, and even some products are at risk of aggravating the symptoms of pox. In conclusion, the acne-removing products on the market at present, whether orally taken or externally applied, have the adverse effects of large irritation, long treatment course, easy generation of side effects and the like. Accordingly, one skilled in the art provides an anti-acne gel containing various plant essences to solve the problems set forth in the background art as described above.
Disclosure of Invention
Based on the technical problems in the background art, the invention provides an acne-removing gel composition containing various plant essences.
In order to achieve the purpose, the invention provides the following technical scheme: an anti-acne gel composition containing multiple plant essences, which comprises: niacinamide, witch hazel extract, lactobacillus/pear juice fermentation product filtrate, barberry bark extract, white willow leaf extract, chinese viola root extract, neem leaf extract, scutellaria root extract, houttuynia cordata extract, glycine max seed extract, wild chrysanthemum flower extract, dandelion extract, hypericum perforatum extract, honeysuckle flower extract, Chinese violet extract, purslane extract, betaine, glycyrrhiza inflate root extract, sodium hyaluronate cross-linked polymer, sodium hyaluronate, acetylated sodium hyaluronate, hydrolyzed sodium hyaluronate, sophora flavescens root extract, salicylic acid, quaternary ammonium salt-73, melaleuca alternifolia leaf oil and the like.
As a further scheme of the invention: the composition comprises the following components in percentage by weight:
Figure BDA0003060556800000021
Figure BDA0003060556800000031
Figure BDA0003060556800000041
as a still further scheme of the invention: the composition comprises the following components in percentage by weight:
Figure BDA0003060556800000042
Figure BDA0003060556800000051
Figure BDA0003060556800000061
as a still further scheme of the invention: the preparation method of the white willow leaf extract specifically comprises the following steps:
(1) pretreatment of raw materials: selecting the fresh salix alba leaves, cleaning, drying, and crushing to 80-100 meshes;
(2) soaking: soaking the above white willow leaf powder in water for 3-6 hr;
(3) acid-base extraction: selecting 65% ethanol solution as extractive solution, and adjusting pH to 2-6 and 8-12 with hydrochloric acid solution and sodium hydroxide solution respectively to obtain white willow leaf extractive solution;
(4) concentrating and drying: concentrating the white willow leaf extract under reduced pressure, and heating and drying to obtain the white willow leaf extract.
As a still further scheme of the invention: the preparation method of the wild chrysanthemum extract specifically comprises the following steps:
(1) pretreatment of raw materials: cleaning flos Chrysanthemi Indici petal, drying, pulverizing, and sieving;
(2) water bath reflux extraction: adding 60-70% ethanol, reflux-extracting for three times (each for 1-3 hr), filtering the extractive solution, and mixing the three filtrates;
(3) and (3) vacuum concentration: and (3) concentrating the combined filtrate in vacuum and drying to obtain the wild chrysanthemum extract.
As a still further scheme of the invention: the preparation method of the phellodendron amurense bark extract specifically comprises the following steps:
(1) pretreatment of raw materials: selecting the bark of phellodendron amurense, cleaning, drying, and crushing to 120 meshes;
(2) ultrasonic extraction: the extracting solution is selected from 40% ethanol solution, ultrasonic electric power of 120-;
(3) concentrating and drying: concentrating the cortex Phellodendri bark extractive solution under reduced pressure, and heating and drying to obtain yellow powdered extract product of cortex Phellodendri bark.
In the invention, the white willow leaf extract contains salicin serving as a medicinal component, has the effects of relieving fever, easing pain, resisting inflammation and the like, and is mainly used as an anti-inflammatory agent in cosmetics and skin care products.
In the invention, the wild chrysanthemum extract contains rich nutrient components, has the effects of diminishing inflammation and resisting bacteria, and can be used for treating symptoms such as skin itch, eczema and the like.
In the invention, the phellodendron amurense bark extract mainly contains berberine, and contains palmatine, phellodendrine, dauricine, sinomenine, phellodendron amurense and the like, and has the effects of promoting the generation of collagen, resisting inflammation and inhibiting odor.
The invention has the beneficial effects that:
1. on the aspect of safety evaluation, the invention has no essence or pigment, and has better safety;
2. in the aspect of skin feel experience, the oil-based skin care product is easy to absorb, has no obvious membrane feel after being smeared and absorbed, has certain moisture retention, is difficult to rub mud, and shows good oily skin-friendly characteristic;
3. on the aspect of the acne removing effect, the acne removing cream integrates four effects of exfoliating and softening cutin, accelerating skin metabolism, controlling excessive secretion of grease, resisting inflammation and allergy, preserving moisture and keeping stability, and has comprehensive acne removing effect and all-round acne resisting effect.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the following embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.
In the embodiment of the invention:
example 1, an anti-acne gel composition comprising various plant essences, the composition comprising: niacinamide, witch hazel extract, lactobacillus/pear juice fermentation product filtrate, barberry bark extract, white willow leaf extract, chinese viola root extract, neem leaf extract, scutellaria root extract, houttuynia cordata extract, glycine max seed extract, wild chrysanthemum flower extract, dandelion extract, hypericum perforatum extract, honeysuckle flower extract, Chinese violet extract, purslane extract, betaine, glycyrrhiza inflate root extract, sodium hyaluronate cross-linked polymer, sodium hyaluronate, acetylated sodium hyaluronate, hydrolyzed sodium hyaluronate, sophora flavescens root extract, salicylic acid, quaternary ammonium salt-73, melaleuca alternifolia leaf oil and the like.
Further, the acne-removing gel composition comprises the following raw materials in percentage by weight:
Figure BDA0003060556800000091
Figure BDA0003060556800000101
Figure BDA0003060556800000111
the preparation method of the embodiment comprises the following steps:
further, the preparation method of the white willow leaf extract comprises the following steps:
(1) pretreatment of raw materials: selecting the above fresh salix alba leaves, cleaning, drying and crushing to 80 meshes;
(2) soaking: soaking the above white willow leaf powder in water for 3 hr;
(3) acid-base extraction: selecting 65% ethanol solution as extracting solution, and adjusting pH to 4 and 8 with hydrochloric acid solution and sodium hydroxide solution respectively to obtain white willow leaf extracting solution;
(4) concentrating and drying: concentrating the white willow leaf extract under reduced pressure, and heating and drying to obtain the white willow leaf extract.
Still further, the preparation method of the wild chrysanthemum extract specifically comprises the following steps:
(1) pretreatment of raw materials: cleaning flos Chrysanthemi Indici petal, drying, pulverizing, and sieving;
(2) water bath reflux extraction: adding 60-70% ethanol, reflux-extracting for three times (each for 1 hr), filtering the extractive solution, and mixing the three filtrates;
(3) and (3) vacuum concentration: and (3) concentrating the combined filtrate in vacuum and drying to obtain the wild chrysanthemum extract.
Further, the preparation method of the phellodendron amurense bark extract specifically comprises the following steps:
(1) pretreatment of raw materials: selecting the above phellodendron amurense barks, cleaning, drying and crushing to 100 meshes;
(2) ultrasonic extraction: the extract is prepared from 40% ethanol solution, ultrasonic power of 150w, action time of 30min, and ultrasonic frequency of 15 kHz. Then filtering the extracting solution;
(3) concentrating and drying: concentrating the cortex Phellodendri bark extractive solution under reduced pressure, and heating and drying to obtain yellow powdered extract product of cortex Phellodendri bark.
Example 2
An anti-acne gel composition containing multiple plant essences, which comprises: niacinamide, witch hazel extract, lactobacillus/pear juice fermentation product filtrate, barberry bark extract, white willow leaf extract, chinese viola root extract, neem leaf extract, scutellaria root extract, houttuynia cordata extract, glycine max seed extract, wild chrysanthemum flower extract, dandelion extract, hypericum perforatum extract, honeysuckle flower extract, Chinese violet extract, purslane extract, betaine, glycyrrhiza inflate root extract, sodium hyaluronate cross-linked polymer, sodium hyaluronate, acetylated sodium hyaluronate, hydrolyzed sodium hyaluronate, sophora flavescens root extract, salicylic acid, quaternary ammonium salt-73, melaleuca alternifolia leaf oil and the like.
Further, the acne-removing gel composition comprises the following raw materials in percentage by weight:
Figure BDA0003060556800000131
Figure BDA0003060556800000141
Figure BDA0003060556800000151
the preparation method of the embodiment comprises the following steps:
further, the preparation method of the white willow leaf extract comprises the following steps:
(1) pretreatment of raw materials: selecting the above fresh salix alba leaves, cleaning, drying, and crushing to 85 meshes;
(2) soaking: soaking the above white willow leaf powder in water for 4 hr;
(3) acid-base extraction: selecting 65% ethanol solution as extracting solution, and adjusting pH to 5 and 10 with hydrochloric acid solution and sodium hydroxide solution respectively to obtain white willow leaf extracting solution;
(4) concentrating and drying: concentrating the white willow leaf extract under reduced pressure, and heating and drying to obtain the white willow leaf extract.
Still further, the preparation method of the wild chrysanthemum extract specifically comprises the following steps:
(1) pretreatment of raw materials: cleaning flos Chrysanthemi Indici petal, drying, pulverizing, and sieving;
(2) water bath reflux extraction: adding 60-70% ethanol, reflux-extracting for three times (2 hr each time), filtering the extractive solution, and mixing the three filtrates;
(3) and (3) vacuum concentration: and (3) concentrating the combined filtrate in vacuum and drying to obtain the wild chrysanthemum extract.
Further, the preparation method of the phellodendron amurense bark extract specifically comprises the following steps:
(1) pretreatment of raw materials: selecting the cortex phellodendri barks, cleaning, drying and crushing to 110 meshes;
(2) ultrasonic extraction: the extract is prepared from 40% ethanol solution, ultrasonic power of 180w, action time of 40min, and ultrasonic frequency of 20 kHz. Then filtering the extracting solution;
(3) concentrating and drying: concentrating the cortex Phellodendri bark extractive solution under reduced pressure, and heating and drying to obtain yellow powdered extract product of cortex Phellodendri bark.
Example 3
An anti-acne gel composition containing multiple plant essences, which comprises: niacinamide, witch hazel extract, lactobacillus/pear juice fermentation product filtrate, barberry bark extract, white willow leaf extract, chinese viola root extract, neem leaf extract, scutellaria root extract, houttuynia cordata extract, glycine max seed extract, wild chrysanthemum flower extract, dandelion extract, hypericum perforatum extract, honeysuckle flower extract, Chinese violet extract, purslane extract, betaine, glycyrrhiza inflate root extract, sodium hyaluronate cross-linked polymer, sodium hyaluronate, acetylated sodium hyaluronate, hydrolyzed sodium hyaluronate, sophora flavescens root extract, salicylic acid, quaternary ammonium salt-73, melaleuca alternifolia leaf oil and the like.
Further, the acne-removing gel composition comprises the following raw materials in percentage by weight:
Figure BDA0003060556800000161
Figure BDA0003060556800000171
Figure BDA0003060556800000181
further, the preparation method of the white willow leaf extract comprises the following steps:
(1) pretreatment of raw materials: selecting the above fresh salix alba leaves, cleaning, drying and crushing to 100 meshes;
(2) soaking: soaking the above white willow leaf powder in water for 6 hr;
(3) acid-base extraction: selecting 65% ethanol solution as extracting solution, and adjusting pH to 6 and 12 with hydrochloric acid solution and sodium hydroxide solution respectively to obtain white willow leaf extracting solution;
(4) concentrating and drying: concentrating the white willow leaf extract under reduced pressure, and heating and drying to obtain the white willow leaf extract.
Still further, the preparation method of the wild chrysanthemum extract specifically comprises the following steps:
(1) pretreatment of raw materials: cleaning flos Chrysanthemi Indici petal, drying, pulverizing, and sieving;
(2) water bath reflux extraction: adding 60-70% ethanol, reflux-extracting for three times (each for 3 hr), filtering the extractive solution, and mixing the three filtrates;
(3) and (3) vacuum concentration: and (3) concentrating the combined filtrate in vacuum and drying to obtain the wild chrysanthemum extract.
Further, the preparation method of the phellodendron amurense bark extract specifically comprises the following steps:
(1) pretreatment of raw materials: selecting the superior phellodendron amurense barks, cleaning, drying and crushing to 120 meshes;
(2) ultrasonic extraction: the extract is prepared from 40% ethanol solution, ultrasonic power of 200w, action time of 60min, and ultrasonic frequency of 25 kHz. Then filtering the extracting solution;
(3) concentrating and drying: concentrating the cortex Phellodendri bark extractive solution under reduced pressure, and heating and drying to obtain yellow powdered extract product of cortex Phellodendri bark.
Comparative example 1
A commercially available acne-removing gel product.
Examples of the experiments
The experimental method comprises the following steps: volunteers with acne on their face, 80 male volunteers and 80 female volunteers aged 20-40 years old were selected and randomly divided into 4 groups of 40 persons, and commercially available acne removing gel products, example 1, example 2 and example 3 were used. The using method comprises the following steps: the paste is directly applied to the affected part of acne after cleaning the face in the morning and evening. Acne removal was tested after 2 weeks, 4 weeks and 8 weeks, respectively. Wherein the removal rate is calculated by the disappearance rate of the number of the whelks, namely the number of the reduced whelks/the total number of the whelks before use. The test results are shown in the following table, and the results of each example and comparative example are the average of the group of 40 volunteers.
TABLE 1 acne removal test recording sheet
Figure BDA0003060556800000201
As can be seen from table 1, the acne removal gel product of the present invention has good acne removal effect, and compared with the commercially available product, the acne removal of example 3 is the highest, reaching 85%.
Next, the evaluation method of the feeling of use was: that is, when commercially available anti-acne gel products, examples 1,2 and 3, were tried out, the test subjects evaluated their feelings of use (main evaluation indexes are extensibility, absorbability, mildness, moisture retention and non-film feeling in use). The using effects of the ingredients are divided into 5 points: the score of 5 is the highest score, which represents good and very satisfactory; 4, the division is better; 3, dividing into acceptable; when the amount is less than 3 points, the results are not acceptable. The experimental results are detailed in table 2 below.
TABLE 2 experience survey record sheet
Figure BDA0003060556800000202
Figure BDA0003060556800000211
As can be seen from the above table, the acne removing gel of the invention has higher scores in five dimensions of extensibility, absorbability, mildness, moisture retention and no membrane feeling than the commercial products, and the scores of all the items in example 3 exceed 4 scores, thereby achieving better and more satisfactory use.
In conclusion, the acne-removing gel composition disclosed by the invention can meet the dual requirements of a user on experience and an acne-removing effect in practical application. In the aspect of experience feeling, the oil-based skin care product is easy to absorb, has no obvious membrane feeling after being smeared and absorbed, has certain moisture retention, is not easy to rub mud, and shows good oily skin-friendly characteristic; in the aspect of safety, the invention has no essence or pigment, and has better safety; in the aspect of effect, the invention integrates four effects of exfoliating and softening cutin, accelerating skin metabolism, controlling excessive secretion of grease, resisting inflammation and allergy and keeping moisture and stable, fully blocks acne, has more comprehensive acne-removing effect and is an ideal acne-removing product.
It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.

Claims (6)

1. An acne-removing gel composition containing multiple plant essences is characterized by comprising the following components: water, butylene glycol, propylene glycol, niacinamide, PEG/PPG-17/6 copolymer, Hamamelis virginiana extract, glycolic acid, PEG-60 hydrogenated castor oil, glyceryl caprylate, lactobacillus/pear juice fermentation product filtrate, white willow leaf extract, radix et rhizoma Rhei extract, neem leaf extract, houttuynia cordata extract, Glycine max seed extract, wild chrysanthemum flower extract, dandelion extract, Hypericum perforatum extract, honeysuckle flower extract, Viola philippinensis extract, phellodendron bark extract, purslane extract, betaine, Glycyrrhiza inflata root extract, Scutellaria baicalensis root extract, isoprene glycol, O-cymene-5-ol, 1, 2-pentanediol, sodium hyaluronate crosspolymer, sodium hyaluronate, sodium acetylated hyaluronate, hydrolyzed sodium hyaluronate, ethylhexyl glycerol, ethylhexylglycerin, ethylhexylated castor oil, ethylhexylated with a glycol, and a mixture of two or more, Radix Sophorae Flavescentis extract, acrylic acid (acrylate)/C10-30 alkanol acrylate cross-linked polymer, triethanolamine, p-hydroxy acetophenone, 1, 2-hexanediol, phenoxyethanol, chlorphenesin, acacia gum, salicylic acid, quaternary ammonium salt-73, bis (hydroxymethyl) imidazolidinyl urea, iodopropynyl butyl carbamate, PEG-40 hydrogenated castor oil, and leaf oil of Melaleuca alternifolia.
2. The acne-removing gel composition containing various plant essences according to claim 1, wherein the composition comprises the following components in percentage by weight:
Figure FDA0003060556790000011
Figure FDA0003060556790000021
Figure FDA0003060556790000031
3. the acne-removing gel composition containing various plant essences according to claim 1, wherein the composition comprises the following components in percentage by weight:
Figure FDA0003060556790000032
Figure FDA0003060556790000041
Figure FDA0003060556790000051
Figure FDA0003060556790000061
4. the acne-removing gel composition containing various plant essences according to claim 1, wherein the preparation method of the white willow leaf extract specifically comprises the following steps:
(1) pretreatment of raw materials: selecting the fresh salix alba leaves, cleaning, drying, and crushing to 80-100 meshes;
(2) soaking: soaking the above white willow leaf powder in water for 3-6 hr;
(3) acid-base extraction: selecting 65% ethanol solution as extractive solution, and adjusting pH to 2-6 and 8-12 with hydrochloric acid solution and sodium hydroxide solution respectively to obtain white willow leaf extractive solution;
(4) concentrating and drying: concentrating the white willow leaf extract under reduced pressure, and heating and drying to obtain the white willow leaf extract.
5. The acne-removing gel composition containing various plant essences according to claim 1, wherein the preparation method of the wild chrysanthemum flower extract specifically comprises the following steps:
(1) pretreatment of raw materials: cleaning flos Chrysanthemi Indici petal, drying, pulverizing, and sieving;
(2) water bath reflux extraction: adding 60-70% ethanol, reflux-extracting for three times (each for 1-3 hr), filtering the extractive solution, and mixing the three filtrates;
(3) and (3) vacuum concentration: and (3) concentrating the combined filtrate in vacuum and drying to obtain the wild chrysanthemum extract.
6. The acne-removing gel composition containing various plant essences according to claim 1, wherein the preparation method of the phellodendron amurense bark extract specifically comprises the following steps:
(1) pretreatment of raw materials: selecting the bark of phellodendron amurense, cleaning, drying, and crushing to 120 meshes;
(2) ultrasonic extraction: the extracting solution is selected from 40% ethanol solution, ultrasonic electric power of 120-;
(3) concentrating and drying: concentrating the cortex Phellodendri bark extractive solution under reduced pressure, and heating and drying to obtain yellow powdered extract product of cortex Phellodendri bark.
CN202110511763.2A 2021-05-11 2021-05-11 Acne-removing gel composition containing various plant essences Pending CN113318019A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115381727A (en) * 2022-09-27 2022-11-25 广州森野生物医药科技有限公司 Whitening and freckle removing composition and preparation method thereof
CN115569099A (en) * 2022-10-24 2023-01-06 浙江海心智惠科技有限公司 Essence and preparation method thereof, and repairing patch and preparation method thereof
CN117137844A (en) * 2023-09-28 2023-12-01 广东领康日用品有限公司 Acne-removing and oil-controlling skin care composition and preparation method thereof

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115381727A (en) * 2022-09-27 2022-11-25 广州森野生物医药科技有限公司 Whitening and freckle removing composition and preparation method thereof
CN115569099A (en) * 2022-10-24 2023-01-06 浙江海心智惠科技有限公司 Essence and preparation method thereof, and repairing patch and preparation method thereof
CN115569099B (en) * 2022-10-24 2024-05-14 浙江海心智惠科技有限公司 Essence, preparation method thereof, repair patch and preparation method thereof
CN117137844A (en) * 2023-09-28 2023-12-01 广东领康日用品有限公司 Acne-removing and oil-controlling skin care composition and preparation method thereof

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