CN113288127B - Hearing detection device and detection method based on time-frequency modulation detection threshold - Google Patents

Hearing detection device and detection method based on time-frequency modulation detection threshold Download PDF

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CN113288127B
CN113288127B CN202110388122.2A CN202110388122A CN113288127B CN 113288127 B CN113288127 B CN 113288127B CN 202110388122 A CN202110388122 A CN 202110388122A CN 113288127 B CN113288127 B CN 113288127B
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frequency modulation
electrical signals
brain electrical
modulation
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CN113288127A (en
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冀飞
陈继跃
郑奕
刘晶
李楠
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6th Medical Center of PLA General Hospital
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/12Audiometering
    • A61B5/121Audiometering evaluating hearing capacity
    • A61B5/125Audiometering evaluating hearing capacity objective methods

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Abstract

The invention belongs to the technical field of hearing test and detection, and particularly relates to a hearing test device based on auditory cortex time-frequency modulation evoked potential, which comprises: the tester terminal is used for sending a sound source emission instruction to the sound source output device; a sound source output device for transmitting a stimulating sound signal with time-frequency modulation to a subject according to a sound source transmission instruction; the guiding electrode is used for recording an electroencephalogram signal after the induction of the auditory cortex potential and the response processing of the auditory neurons to the stimulation sound signal with the time frequency modulation; the reference electrode is used for recording an electroencephalogram signal recorded by the guide electrode and providing a reference electroencephalogram signal; the data processing terminal is used for processing the received brain electrical signals and the reference brain electrical signals, then carrying out speech sound time domain and frequency domain modulation processing on the received brain electrical signals, separating to obtain a plurality of groups of processing signals consisting of time modulation rate and frequency modulation density, drawing a test waveform curve, and detecting the hearing condition of a subject according to the test waveform curve.

Description

Hearing detection device and detection method based on time-frequency modulation detection threshold
Technical Field
The invention belongs to the technical field of hearing test and detection, and particularly relates to a hearing detection device and a detection method based on a time-frequency modulation perception threshold.
Background
Currently, there are many methods of treatment for patients with ear disease, but a comprehensive hearing test is performed prior to diagnosis. Pure tone audiometry is one of the most popular and effective examination methods in the otology field, and plays a vital role in clinical applications. It is an inspection technique that learns the functional state of the auditory system by observing, recording and analyzing the response of a subject to controllable acoustic stimuli. The doctor can diagnose the property of deafness, the degree of hearing disorder, the quality of residual hearing and the like through detection, more importantly, the single-ear hearing loss condition can be obtained, and parameter basis is provided for wearing the hearing aid, so that different types of hearing aid products can be correctly selected according to actual conditions.
In most of the existing hospitals, the hearing of the detected person is detected manually, in the process, the detected person is often required to be subjected to explanation of the detection rule, and then the detection sound is required to be correspondingly adjusted according to the actual detection condition of the detected person. Although such a detection process is simple, long-time work also causes the detection personnel to feel boring, repeated detection often takes up much effort and time of the detection personnel, the work efficiency of the detection personnel is greatly reduced, and in addition, subjective detection results cannot be obtained due to the fact that detection results are interfered manually in some cases.
Disclosure of Invention
In order to solve the above-mentioned drawbacks of the prior art, the present invention provides a hearing test device based on auditory cortex time-frequency modulation evoked potential, the device comprising: the device comprises a tester terminal, a sound source output device, a plurality of reference electrodes, a grounding electrode, a guide electrode and a data processing terminal;
the tester terminal is used for sending a sound source emission instruction to the sound source output device;
the sound source output device is arranged in the ear of the subject and is used for transmitting a stimulating sound signal with time-frequency modulation to the subject according to a sound source transmitting instruction;
the guiding electrode is arranged at the top of the cranium of the subject, is used for recording the brain electrical signals after the induced auditory cortex potential and auditory neuron response processing of the stimulation acoustic signals with time frequency modulation, and inputs the brain electrical signals to the data processing terminal;
the grounding electrode is arranged on the low forehead of the subject and used as a grounding electrode for generating a grounding signal;
the reference electrode is arranged at the earlobe or mastoid of the subject, and is used for recording the brain electrical signals recorded by the guide electrode, providing reference brain electrical signals and inputting the reference brain electrical signals to the data processing terminal;
the data processing terminal is used for processing the received brain electrical signals and the reference brain electrical signals to obtain processed brain electrical signals, carrying out speech sound time domain and frequency domain modulation processing on the processed brain electrical signals, separating to obtain a plurality of groups of processing signals consisting of time modulation rate and frequency modulation density, drawing a test waveform curve by taking the time modulation rate as an abscissa and the frequency modulation density as an ordinate, and detecting the hearing condition of a subject according to the test waveform curve.
As one of the improvements of the above technical solutions, the stimulating acoustic signal with time-frequency modulation is:
S(x,t)=A×[2π×(ωt+Ωx)+Φ]
wherein S (x, t) is a stimulus sound signal with time-frequency modulation emitted at time t, i.e. a function of time (t) and logarithmic frequency (x), x=log2 (f/f 1); f is the sound frequency of the stimulation sound signal with time frequency modulation, and f1 is the minimum frequency; a is the frequency modulation amplitude of the traveling wave, and is determined by properly adjusting the modulation depth of all carrier waves simultaneously; when the value A is set to be between 0 and 1, the frequency modulation of the corresponding flat traveling wave envelope is between 0 and 100 percent; omega is the frequency density per octave cycle (c/o), phi is the initial phase of frequency modulation of carrier randomization expressed in radians, ranging from 0 to 2 pi; ω is the time modulation rate expressed in terms of number of scans per second (Hz), i.e. Hz/s.
As one of the improvements of the above technical solutions, the data processing terminal includes: the signal processing module and the curve generating module;
the signal processing module is used for processing the received brain electrical signals and the reference brain electrical signals to obtain processed brain electrical signals; the processed electroencephalogram signal is the electroencephalogram signal minus a reference electroencephalogram signal;
the curve generation module is used for carrying out speech sound time domain and frequency domain modulation processing on the processed electroencephalogram signals, separating to obtain a plurality of groups of processing signals consisting of time modulation rate and frequency modulation density, drawing a test waveform curve by taking the time modulation rate as an abscissa and the frequency modulation density as an ordinate, and detecting the hearing condition of a subject according to the test waveform curve.
As an improvement of the above-described aspects, the hearing profile of the subject comprises: the auditory cortex time-frequency modulation evoked potential threshold, the incubation period and the vibration fortune are respectively abnormal in time modulation rate and frequency modulation density of the test waveform curve.
As one of the improvements of the above technical solutions, the time of the stimulation interval is 500ms.
As one of the improvements of the above technical scheme, the sound source output device is an earphone.
The invention also provides a hearing test method based on the time-frequency modulation perception threshold, which comprises the following steps:
the tester terminal sends a sound source emission instruction to a sound source output device;
the sound source output device transmits a stimulating sound signal with time frequency modulation to a subject according to a sound source transmission instruction;
the guiding electrode records the brain electrical signals after the induction of the auditory cortex potential and the response processing of the auditory neurons on the stimulation acoustic signals with time frequency modulation, and inputs the brain electrical signals to the data processing terminal;
the reference electrode setting record provides a reference brain electrical signal for the brain electrical signal recorded by the guide electrode and inputs the reference brain electrical signal to the data processing terminal;
the data processing terminal processes the received brain electrical signals and the reference brain electrical signals to obtain processed brain electrical signals, carries out speech sound time domain and frequency domain modulation processing on the processed brain electrical signals, separates to obtain a plurality of groups of processed signals consisting of time modulation rate and frequency modulation density, draws a test waveform curve by taking the time modulation rate as an abscissa and the frequency modulation density as an ordinate, and detects the hearing condition of a subject according to the test waveform curve.
As one of the improvements of the above technical solution, the data processing terminal processes the received electroencephalogram signal and the reference electroencephalogram signal to obtain a processed electroencephalogram signal, and performs speech sound time domain and frequency domain modulation processing on the processed electroencephalogram signal, separates to obtain a plurality of groups of processed signals composed of time modulation rate and frequency modulation density, and draws a test waveform curve by taking the time modulation rate as an abscissa and the frequency modulation density as an ordinate, and detects the hearing condition of a subject according to the test waveform curve; the specific process is as follows:
the signal processing module processes the received brain electrical signals and the reference brain electrical signals to obtain processed brain electrical signals; the processed electroencephalogram signal is the electroencephalogram signal minus a reference electroencephalogram signal;
the curve generation module carries out speech sound time domain and frequency domain modulation processing on the processed electroencephalogram signals, separates to obtain a plurality of groups of processing signals composed of time modulation rate and frequency modulation density, draws a test waveform curve by taking the time modulation rate as an abscissa and the frequency modulation density as an ordinate, and detects the hearing condition of a subject according to the test waveform curve.
Compared with the prior art, the invention has the beneficial effects that:
the device can intuitively detect whether the time-frequency modulation stimulation sound signal has an abnormal signal or not, greatly improves the working efficiency, can obtain a subjective detection result very accurately without manual interference of the detection result, and avoids the problem of low accuracy caused by manual objective detection result; the whole detection process does not need manual operation, and the detection efficiency is greatly improved.
Drawings
FIG. 1 is a schematic diagram of a hearing test device based on a time-frequency modulated perception threshold in accordance with the present invention;
fig. 2 is a flow chart of a hearing test method based on a time-frequency modulated perception threshold in accordance with the present invention.
Detailed Description
The invention will now be further described with reference to the accompanying drawings.
As shown in fig. 1, the present invention provides a hearing test device based on a time-frequency modulation perception threshold, the device comprising: the device comprises a tester terminal, a sound source output device, a plurality of reference electrodes, a grounding electrode, a guide electrode and a data processing terminal;
the tester terminal is used for sending a sound source emission instruction to the sound source output device;
the sound source output device is arranged in the ear of the subject and is used for continuously transmitting a time-frequency modulation stimulation sound signal with a stimulation interval to the subject according to a sound source transmission instruction; wherein the time of the stimulus interval is 500ms;
wherein, the stimulating sound signal with time frequency modulation is:
S(x,t)=A×[2π×(ωt+Ωx)+Φ]
where S (x, t) is a function of the stimulus sound signal with time frequency modulation, i.e. the time (t) and the logarithmic frequency (x), x=log2 (f/f 1; f is the sound frequency of the stimulus sound signal with time frequency modulation, f1 is the smallest frequency, a is the travelling wave frequency modulation amplitude, determined by the modulation depth of all carrier waves being properly adjusted simultaneously, when the value a is set between 0 and 1, the frequency modulation of its corresponding flat travelling wave envelope is 0 to 100%, Ω is the frequency density per octave cycle (cycle/octave, c/o), Φ is the frequency modulation initial phase of the carrier randomization in radians, ranging from 0 to 2 pi, ω is the time modulation rate, expressed in the number of scans per second (Hz), i.e. Hz/S.
Preferably, the sound source output device is an earphone.
The guiding electrode is arranged at the top of the cranium of the subject, is used for recording the brain electrical signals after the induced auditory cortex potential and auditory neuron response processing of the stimulation acoustic signals with time frequency modulation, and inputs the brain electrical signals to the data processing terminal;
the grounding electrode is arranged on the low forehead of the subject and used as a grounding electrode for generating a grounding signal;
the reference electrode is arranged at the earlobe or mastoid of the subject, and is used for recording the brain electrical signals recorded by the guide electrode, providing reference brain electrical signals and inputting the reference brain electrical signals to the data processing terminal;
the data processing terminal is used for processing the received brain electrical signals and the reference brain electrical signals to obtain processed brain electrical signals, carrying out speech sound time domain and frequency domain modulation processing on the processed brain electrical signals, separating to obtain a plurality of groups of processing signals consisting of time modulation rate and frequency modulation density, drawing a test waveform curve by taking the time modulation rate as an abscissa and the frequency modulation density as an ordinate, and detecting the hearing condition of a subject according to the test waveform curve.
Specifically, the data processing terminal includes: the signal processing module and the curve generating module;
the signal processing module is used for processing the received brain electrical signals and the reference brain electrical signals to obtain processed brain electrical signals; the processed electroencephalogram signal is the electroencephalogram signal minus a reference electroencephalogram signal;
the curve generation module is used for carrying out speech sound time domain and frequency domain modulation processing on the processed electroencephalogram signals, separating to obtain a plurality of groups of processing signals consisting of time modulation rate and frequency modulation density, drawing a test waveform curve by taking the time modulation rate as an abscissa and the frequency modulation density as an ordinate, and detecting the hearing condition of a subject according to the test waveform curve.
Wherein the hearing profile of the subject comprises: the auditory cortex time-frequency modulation evoked potential threshold, the incubation period and the vibration fortune are respectively abnormal in time modulation rate and frequency modulation density of the test waveform curve.
As shown in fig. 2, the present invention further provides a hearing test method based on a time-frequency modulation perception threshold, the method comprising:
the tester terminal sends a sound source emission instruction to a sound source output device;
the sound source output device transmits a stimulating sound signal with time frequency modulation to a subject according to a sound source transmission instruction;
the guiding electrode records the brain electrical signals after the induction of the auditory cortex potential and the response processing of the auditory neurons on the stimulation acoustic signals with time frequency modulation, and inputs the brain electrical signals to the data processing terminal;
the reference electrode setting record provides a reference brain electrical signal for the brain electrical signal recorded by the guide electrode and inputs the reference brain electrical signal to the data processing terminal;
the data processing terminal processes the received brain electrical signals and the reference brain electrical signals to obtain processed brain electrical signals, carries out speech sound time domain and frequency domain modulation processing on the processed brain electrical signals, separates to obtain a plurality of groups of processed signals consisting of time modulation rate and frequency modulation density, draws a test waveform curve by taking the time modulation rate as an abscissa and the frequency modulation density as an ordinate, and detects the hearing condition of a subject according to the test waveform curve.
Specifically, the signal processing module processes the received brain electrical signals and the reference brain electrical signals to obtain processed brain electrical signals; the processed electroencephalogram signal is the electroencephalogram signal minus a reference electroencephalogram signal;
the curve generation module carries out speech sound time domain and frequency domain modulation processing on the processed electroencephalogram signals, separates to obtain a plurality of groups of processing signals composed of time modulation rate and frequency modulation density, draws a test waveform curve by taking the time modulation rate as an abscissa and the frequency modulation density as an ordinate, and detects the hearing condition of a subject according to the test waveform curve.
The hearing profile of the subject includes: the auditory cortex time-frequency modulation evoked potential threshold, the incubation period and the vibration fortune are respectively abnormal in time modulation rate and frequency modulation density of the test waveform curve.
Specifically, speech sound time domain and frequency domain modulation (time frequency modulation for short) refers to a technology of outputting signals which show a section of a specific frequency domain modulation density and a specific time domain modulation rate after a voice input signal passes through an external Zhou Tingjiao filter bank system established by Matlab, namely, outputting signals which show the amount of time frequency modulation components of the voice signal on a time rate and a frequency density in a certain range. And uploading the audio signals modulated by speech sound time frequency to a custom sound source module of a scientific research module of the hearing evoked potential instrument, outputting the audio signals through an inserted earphone, and carrying out weighted calibration through a sound level meter. The auditory cortex time-frequency modulation evoked potential is that the auditory cortex long latency potential is evoked by time-frequency modulation, and the threshold value, latency and amplitude of the auditory cortex time-frequency modulation evoked potential are recorded.
In this embodiment, a red recording electrode and a blue recording electrode are placed on the right and left mastoid or earlobe of the subject, respectively, as reference electrodes; placing a white recording electrode on the top of the cranium of the subject as a recording electrode; a black recording electrode was placed on the low forehead of the subject as a ground level. The detection process of the auditory cortex time-frequency modulation evoked potential threshold value comprises the following steps:
the detection of the auditory cortex time-frequency modulation evoked potential threshold begins at 60dB nHL, P1, N1 and P2 waves are recorded, each wave is repeated three times, the stimulation intensity of the transmitted stimulation sound signal with time-frequency modulation is determined to be gradually increased by 10dB or reduced by 10dB, then the stimulation intensity is increased by 5dB again until the last group of wave forms disappear, the overlapping is repeated three times, the wave forms are free from repeatability, namely the stimulation intensity corresponding to the stimulation sound signal with time-frequency modulation in the last group is the potential threshold, the potential threshold is used as the hearing domain of a subject, and the hearing state of the subject is detected according to the hearing domain;
if the hearing domain is greater than or equal to a preset hearing domain threshold, the hearing state of the subject is good;
if the hearing domain is less than the predetermined hearing domain threshold, the hearing state of the subject is poor.
The detection process of the incubation period is as follows:
according to the obtained test curve, acquiring the transverse length of each period of the waveform as an actual measurement latency, comparing the actual measurement latency with a preset latency threshold, and detecting the hearing state of a subject; wherein, the positive waveform and the negative waveform of the waveform curve are set as one period;
if the measured latency is greater than or equal to a pre-set latency threshold, the hearing state of the subject is poor;
if the measured latency is less than the pre-set latency threshold, the hearing state of the subject is good.
The detection process of the amplitude is as follows:
according to the obtained test curve, the longitudinal length of each period of the waveform is obtained and used as the actual measurement amplitude, and the actual measurement amplitude is compared with a preset amplitude threshold value to detect the hearing state of the subject; wherein, the longitudinal length of the positive waveform or the negative waveform of the waveform curve is the longitudinal length of one period;
if the measured amplitude is greater than or equal to a preset amplitude threshold, the hearing state of the subject is good;
if the measured amplitude is less than the preset amplitude threshold, the hearing state of the subject is poor.
The detection process for whether the time modulation rate and the frequency modulation density of the test waveform curve are abnormal or not comprises the following steps:
recording P1, N1 and P2 waves from 60dB nHL, repeating each wave form for three times, determining that the stimulus intensity of the transmitted stimulus sound signal with time-frequency modulation is gradually increased by 10dB or reduced by 10dB, then increasing by 5dB again until the last group of wave forms disappear, repeatedly overlapping the wave forms for three times, and detecting whether the stimulus sound signal with time-frequency modulation has abnormal signals or not intuitively according to the obtained test wave form curve compared with the preset standard wave form curve, thereby greatly improving the working efficiency.
Finally, it should be noted that the above embodiments are only for illustrating the technical solution of the present invention and are not limiting. Although the present invention has been described in detail with reference to the embodiments, it should be understood by those skilled in the art that modifications and equivalents may be made thereto without departing from the spirit and scope of the present invention, which is intended to be covered by the appended claims.

Claims (4)

1. A hearing test device based on a time-frequency modulated signal, the device comprising: the device comprises a tester terminal, a sound source output device, a plurality of reference electrodes, a grounding electrode, a guide electrode and a data processing terminal;
the tester terminal is used for sending a sound source emission instruction to the sound source output device;
the sound source output device is arranged in the ear of the subject and is used for transmitting a stimulating sound signal with time-frequency modulation to the subject according to a sound source transmitting instruction;
the guiding electrode is arranged at the top of the cranium of the subject, is used for recording the brain electrical signals after the induced auditory cortex potential and auditory neuron response processing of the stimulation acoustic signals with time frequency modulation, and inputs the brain electrical signals to the data processing terminal;
the grounding electrode is arranged on the low forehead of the subject and used as a grounding electrode for generating a grounding signal;
the reference electrode is arranged at the earlobe or mastoid of the subject, and is used for recording the brain electrical signals recorded by the guide electrode, providing reference brain electrical signals and inputting the reference brain electrical signals to the data processing terminal;
the data processing terminal is used for processing the received brain electrical signals and the reference brain electrical signals to obtain processed brain electrical signals, carrying out speech sound time domain and frequency domain modulation processing on the processed brain electrical signals, separating to obtain a plurality of groups of processing signals consisting of time modulation rate and frequency modulation density, drawing a test waveform curve by taking the time modulation rate as an abscissa and the frequency modulation density as an ordinate, and detecting the hearing condition of a subject according to the test waveform curve;
the data processing terminal includes: the signal processing module and the curve generating module;
the signal processing module is used for processing the received brain electrical signals and the reference brain electrical signals to obtain processed brain electrical signals; the processed electroencephalogram signal is the electroencephalogram signal minus a reference electroencephalogram signal;
the curve generation module is used for carrying out speech sound time domain and frequency domain modulation processing on the processed electroencephalogram signals, separating to obtain a plurality of groups of processing signals consisting of time modulation rate and frequency modulation density, drawing a test waveform curve by taking the time modulation rate as an abscissa and the frequency modulation density as an ordinate, and detecting the hearing condition of a subject according to the test waveform curve;
the hearing profile of the subject includes: the auditory cortex time-frequency modulation evoked potential threshold, latency and amplitude are respectively abnormal in time modulation rate and frequency modulation density of the test waveform curve.
2. The hearing test device of claim 1, wherein the stimulus sound signal with time-frequency modulation is:
S(x,t)=A×[2π×(ωt+Ωx)+Φ]
s (x, t) is a stimulating sound signal with time-frequency modulation emitted at the moment t; x=log2 (f/f 1); f is the sound frequency of the stimulation sound signal with time frequency modulation, and f1 is the minimum frequency; a is the frequency modulation amplitude of the traveling wave, and is determined by properly adjusting the modulation depth of all carrier waves simultaneously; when the value A is set to be between 0 and 1, the frequency modulation of the corresponding flat traveling wave envelope is between 0 and 100 percent; omega is the frequency density of each octave period, phi is the frequency modulation initial phase of carrier randomization expressed in radian, and the range is from 0 to 2 pi; ω is the time modulation rate.
3. The hearing test device based on time-frequency modulated signals according to claim 1, wherein the stimulation interval is 500ms.
4. The hearing test device of claim 1, wherein the sound source output device is a headset.
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