CN113197930A - Processing method of dried codonopsis pilosula - Google Patents
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- CN113197930A CN113197930A CN202110542497.XA CN202110542497A CN113197930A CN 113197930 A CN113197930 A CN 113197930A CN 202110542497 A CN202110542497 A CN 202110542497A CN 113197930 A CN113197930 A CN 113197930A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/344—Codonopsis
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B5/00—Drying solid materials or objects by processes not involving the application of heat
- F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
- F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
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- A—HUMAN NECESSITIES
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/13—Preparation or pretreatment of starting material involving cleaning, e.g. washing or peeling
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/17—Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting
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Abstract
The invention discloses a processing method of a dried codonopsis pilosula product, and belongs to the technical field of traditional Chinese medicine processing. The method comprises the following steps: removing the epidermis of fresh codonopsis pilosula, cleaning, draining water on the surface, pre-freezing at-45 to-35 ℃ for 3-6 hours, placing in a freeze dryer with the vacuum degree of 5-100 Pa, controlling the treatment temperature to be increased from-75 to-30 ℃ to 0 ℃ in a staged manner, then increasing the temperature from 0 ℃ to 40-60 ℃ in a staged manner, and obtaining the dried codonopsis pilosula after the treatment is finished. The method provided by the invention can maximally keep the codonopsis pilosula fresh, so that sulfur fumigation in the traditional dried codonopsis pilosula processing process is replaced, the prepared codonopsis pilosula is not easy to leak oil, is non-toxic to human bodies and environment-friendly, and can maximally retain the effective components and curative effect of traditional Chinese medicinal materials.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicine processing, and particularly relates to a processing method of a dried codonopsis pilosula product.
Background
Codonopsis pilosula is sweet in flavor and neutral in nature. Has effects in invigorating spleen, replenishing qi, quenching thirst, invigorating spleen, tonifying lung, nourishing blood, and promoting salivation. Can be used for treating deficiency of spleen-lung qi, anorexia, listlessness, cough, asthma, deficiency of qi and blood, sallow complexion, palpitation, short breath, thirst due to body fluid consumption, and internal heat. Laziness in speaking, weakness of limbs, poor appetite, qi deficiency, deficiency of both qi and fluid, deficiency of both qi and blood, and sallow complexion due to blood deficiency. However, the exterior syndrome is not relieved but the interior syndrome is full of pathogenic factors. The product has similar efficacy to Ginseng radix, but weak potency. For general deficiency syndrome, it can be used in place of Ginseng radix; for severe deficiency syndrome, ginseng should be used.
The codonopsis pilosula is usually dug and cleaned in autumn and dried in a sun-drying mode, but in the sun-drying process, effective components such as vegetable proteins, microorganisms and volatile oil can be damaged and are easily polluted, and the contents of ash, microorganisms and the like are easily exceeded.
The traditional Chinese medicine drying process includes the steps of manual sorting, bundling, kneading, airing, drying in a drying room and the like, and has the advantages of large workload, long period, low drying efficiency, high labor cost and great increase of the cost of Chinese medicine decoction pieces.
Disclosure of Invention
The invention aims to provide a processing method of dried codonopsis pilosula, aiming at the defects of the method, and the method can keep the freshness to the maximum degree, namely the effective components and curative effect of the traditional Chinese medicinal materials to the maximum degree.
The invention aims to provide a processing method of a dried codonopsis pilosula product, which comprises the following steps:
removing the epidermis of fresh codonopsis pilosula, cleaning, draining water on the surface, pre-freezing at-45 to-35 ℃ for 3-6 hours, placing in a freeze dryer with the vacuum degree of 5-100 Pa, controlling the treatment temperature to be increased from-75 to-30 ℃ to 0 ℃ in a staged manner, then increasing the temperature from 0 ℃ to 40-60 ℃ in a staged manner, and obtaining the dried codonopsis pilosula after the treatment is finished.
Preferably, the temperature is increased to 0 ℃ from-75 to-30 ℃ in a staged manner, heat preservation treatment is carried out in six stages, the temperature difference between two adjacent stages is 5-20 ℃, and the heat preservation time of each stage is 1-4 hours; heating from 0 ℃ to 40-60 ℃ in a staged manner, carrying out heat preservation treatment in four stages, wherein the temperature difference between two adjacent stages is 5-20 ℃, and the heat preservation time of each stage is 1-4 hours.
More preferably, the temperature rise rate of the two adjacent stages is 5-10 ℃/h.
Preferably, the vacuum degree is 65-88 Pa.
Preferably, fresh codonopsis pilosula is sliced before processing, the slicing thickness is 2-3 mm, and the stacking thickness is less than or equal to 20mm when the codonopsis pilosula is placed in a freeze dryer.
The invention also provides a dried codonopsis pilosula prepared by the method.
Compared with the prior art, the invention has the following beneficial effects:
the processing method of the dried codonopsis pilosula provided by the invention can keep freshness to the greatest extent, avoids the increase of ash content and the reduction of extract in the drying process of the codonopsis pilosula, and the moisture content of the codonopsis pilosula dried by the method is far lower than that of the codonopsis pilosula obtained by adopting the existing drying technology, so that the quality of medicinal materials can be effectively improved.
The method provided by the invention replaces sulfur fumigation in the traditional processing process of dried codonopsis pilosula products, and the prepared codonopsis pilosula is not easy to lose oil, is non-toxic to human bodies and non-pollution to the environment, and can retain the effective components and curative effects of traditional Chinese medicinal materials to the maximum extent.
Detailed Description
In order to make the technical solutions of the present invention better understood and enable those skilled in the art to practice the present invention, the following embodiments are further described, but the present invention is not limited to the following embodiments.
In the following examples, a freeze dryer is used to wipe out a freeze dryer cold trap with a clean towel during vacuum drying (device preparation process); directly placing fresh radix Codonopsis into a material tray, placing the material tray into a shelf of a material rack, respectively placing a material temperature-sensing probe into the radix Codonopsis material, carefully placing the material rack into a cold trap, and finally covering with an organic glass cover. Switching on a power supply, pressing any key to enter a main interface, clicking a key of a refrigerator on a screen, starting a refrigerating system, and starting the pre-freezing of the codonopsis pilosula material (material pre-freezing process); after the material is pre-frozen, setting the freeze-drying process section and section temperature, lifting a material tray, placing a cover plate on the opening of a cold well, placing a material tray on the cover plate, covering a glass cover, clicking an 'automatic operation' button, starting a vacuum pump, a vacuum gauge and a temperature control program at the same time, starting the vacuum pump, and starting freeze-drying according to the set program (freeze-drying process); and after the freeze drying is finished, stopping the machine and taking samples. And (4) closing the refrigeration, opening the inflation valve, then closing the vacuum pump, and taking out the sample (stopping the sampling process).
Example 1
A processing method of dried codonopsis pilosula comprises the following steps:
removing epidermis from fresh radix Codonopsis, cleaning, draining water, cutting into slices with thickness of about 2.5mm, placing in a freeze dryer, stacking at thickness of less than or equal to 20mm, pre-freezing at-43 deg.C for 5 hr, setting vacuum degree at 76-81Pa, controlling temperature to increase from-45 deg.C to 0 deg.C in stages, increasing temperature from 0 deg.C to 45 deg.C in stages, and automatically drying radix Codonopsis at temperature increasing rate of 5 deg.C/h in two adjacent stages; the temperature and the heat preservation time of the specific staged treatment are as follows:
a first stage: -45 ℃ and a temperature of 3h
And (2) second stage: -30 ℃ and a temperature of 3h
And (3) three stages: at 25 ℃ below zero for 2h20min
And a fourth stage: -20 ℃ and a temperature of 3h
Five stages: -10 ℃ and a temperature of 2
Six sections: 0 ℃ and a temperature of 3h
Seven sections: 10 ℃ and the temperature of 2h30min
Eight sections: at 25 ℃ and a temperature of 3h
Nine sections: 35 ℃ at a temperature of 2h
Ten sections: the temperature is 45 ℃ and 3 h; the codonopsis pilosula is obtained after vacuum freeze drying.
Example 2
A processing method of dried codonopsis pilosula comprises the following steps:
removing epidermis from fresh radix Codonopsis, cleaning, draining water on surface, cutting into pieces with thickness of about 2.5mm, placing in a freeze dryer, stacking at thickness of less than or equal to 20mm, pre-freezing at-45 deg.C for 5h, setting vacuum degree at 74-78Pa, controlling temperature to increase from-45 deg.C to 0 deg.C in stages, increasing temperature from 0 deg.C to 45 deg.C in stages, and automatically drying radix Codonopsis at temperature increasing rate of 10 deg.C/h in two adjacent stages; the specific staged treatment temperature is as follows:
a first stage: -45 ℃ and a temperature of 3h
And (2) second stage: -30 ℃ and a temperature of 3h
And (3) three stages: -25 ℃ at a temperature of 2h
And a fourth stage: -20 ℃ and a temperature of 3h
Five stages: at-10 deg.C for 2h15min
Six sections: 0 ℃ and a temperature of 3h
Seven sections: 10 ℃ at a temperature of 2h
Eight sections: at 25 ℃ and a temperature of 3h
Nine sections: 35 ℃ at a temperature of 2h
Ten sections: the temperature is 45 ℃ and 3 h; thus obtaining the dried codonopsis pilosula.
Example 3
A processing method of dried codonopsis pilosula comprises the following steps:
removing the epidermis of fresh codonopsis pilosula, cleaning, draining water on the surface, cutting into slices with the thickness of about 2.5mm, placing the slices in a freeze dryer, stacking the slices with the thickness of less than or equal to 20mm, pre-freezing the slices for 5 hours at the temperature of minus 45 ℃, setting the vacuum degree to be within the range of 79-84 Pa, controlling the temperature to be increased from minus 45 ℃ to 0 ℃ in a staged manner, increasing the temperature to 45 ℃ in a staged manner from 0 ℃ for treatment, selecting the temperature increase rate of 8 ℃/h in two adjacent stages, and automatically drying the codonopsis pilosula; the drying temperature and the treatment time of the specific staged treatment are as follows:
a first stage: -45 ℃ and a temperature of 3h
And (2) second stage: -30 ℃ and a temperature of 3h
And (3) three stages: -25 ℃ and a temperature of 3h
And a fourth stage: -20 ℃ and a temperature of 3h
Five stages: 10 ℃ below zero, temperature 2h
Six sections: 0 ℃ and a temperature of 3h
Seven sections: 10 ℃ at a temperature of 2h
Eight sections: at 25 ℃ and a temperature of 3h
Nine sections: 35 ℃ at a temperature of 2h
Ten sections: at 45 ℃, the temperature is 3h and 15 min; thus obtaining the dried codonopsis pilosula.
Example 4
A processing method of dried codonopsis pilosula comprises the following steps:
removing epidermis from fresh radix Codonopsis, cleaning, draining water on the surface, cutting into pieces with thickness of about 2.5mm, placing in a freeze dryer, stacking at thickness of less than or equal to 20mm, pre-freezing at-45 deg.C for 5h, setting vacuum degree within 81-85 Pa, controlling temperature from-45 deg.C to 0 deg.C in a staged manner, heating from 0 deg.C to 45 deg.C in a staged manner, selecting heating rate of 10 deg.C/h in two adjacent stages, and automatically drying radix Codonopsis; the drying temperature and the treatment time of the specific staged treatment are as follows:
a first stage: -45 ℃ and a temperature of 2h
And (2) second stage: -30 ℃ and a temperature of 3h
And (3) three stages: at 25 ℃ below zero for 2h30min
And a fourth stage: -20 ℃ and a temperature of 3h
Five stages: 10 ℃ below zero, temperature 2h
Six sections: 0 ℃ and a temperature of 3h
Seven sections: 10 ℃ at a temperature of 2h
Eight sections: at 25 ℃ and a temperature of 3h
Nine sections: 35 ℃ at a temperature of 2h
Ten sections: the temperature is 45 ℃ and 3 h; thus obtaining the dried codonopsis pilosula.
Example 5
A processing method of dried codonopsis pilosula comprises the following steps:
removing epidermis from fresh radix Codonopsis, cleaning, draining water on the surface, cutting into pieces with thickness of about 2.5mm, placing in a freeze dryer, stacking at thickness of less than or equal to 20mm, pre-freezing at-45 deg.C for 5h, setting vacuum degree at 77-80 Pa, controlling temperature to increase from-45 deg.C to 0 deg.C in a staged manner, increasing temperature from 0 deg.C to 45 deg.C in a staged manner, selecting temperature increase rate of 10 deg.C/h in two adjacent stages, and automatically drying radix Codonopsis; the drying temperature and the treatment time of the specific staged treatment are as follows:
a first stage: -45 ℃ and a temperature of 2h
And (2) second stage: -30 ℃ and a temperature of 3h
And (3) three stages: -25 ℃ and a temperature of 3h
And a fourth stage: -20 ℃ and a temperature of 3h
Five stages: -10 ℃ at a temperature of 3h
Six sections: 0 ℃ and a temperature of 3h
Seven sections: 10 ℃ at a temperature of 2h
Eight sections: at 25 ℃ and a temperature of 3h
Nine sections: 35 ℃ at a temperature of 2h
Ten sections: the temperature is 45 ℃ and 3 h; thus obtaining the dried codonopsis pilosula.
Example 6
A processing method of dried codonopsis pilosula comprises the following steps:
removing epidermis from fresh radix Codonopsis, cleaning, draining water on surface, cutting into pieces with thickness of about 2.5mm, placing in a freeze dryer, stacking at thickness of less than or equal to 20mm, pre-freezing at-45 deg.C for 5h, setting vacuum degree at 73-79Pa, controlling temperature to increase from-45 deg.C to 0 deg.C in a staged manner, increasing temperature from 0 deg.C to 45 deg.C in a staged manner, selecting temperature increase rate of 10 deg.C/h in two adjacent stages, and automatically drying radix Codonopsis; the drying temperature and the treatment time of the specific staged treatment are as follows:
a first stage: keeping the temperature at minus 45 ℃ for 3h
And (2) second stage: keeping the temperature at minus 45 ℃ for 3h
And (3) three stages: keeping the temperature at minus 30 ℃ for 2h
And a fourth stage: keeping the temperature at 15 ℃ below zero for 2h
Five stages: keeping the temperature at 0 ℃ for 3h
Six sections: keeping the temperature at 10 ℃ for 3h
Seven sections: keeping the temperature at 20 ℃ for 3h
Eight sections: keeping the temperature at 30 ℃ for 2h
Nine sections: keeping the temperature at 40 ℃ for 3h
Ten sections: keeping the temperature at 45 ℃ for 2 h; thus obtaining the dried codonopsis pilosula.
Example 7
A processing method of dried codonopsis pilosula comprises the following steps:
removing epidermis from fresh radix Codonopsis, cleaning, draining water on the surface, cutting into pieces with thickness of about 2.5mm, placing in a freeze dryer, stacking at thickness of less than or equal to 20mm, pre-freezing at-45 deg.C for 5h, setting vacuum degree in the range of 69-82 Pa, controlling temperature to increase from-45 deg.C to 0 deg.C in a staged manner, increasing temperature from 0 deg.C to 45 deg.C in a staged manner, selecting two adjacent stages with heating rate of 10 deg.C/h, and automatically drying radix Codonopsis; the drying temperature and the treatment time of the specific staged treatment are as follows:
a first stage: -45 ℃ and a temperature of 3h
And (2) second stage: -30 ℃ and a temperature of 3h
And (3) three stages: -25 ℃ and a temperature of 3h
And a fourth stage: -20 ℃ at a temperature of 2h
Five stages: -10 ℃ at a temperature of 3h
Six sections: 0 ℃ and a temperature of 2h10min
Seven sections: 10 ℃ at a temperature of 3h
Eight sections: at 25 ℃ and a temperature of 3h
Nine sections: 35 ℃ at a temperature of 2h
Ten sections: the temperature is 45 ℃ and 2 h; thus obtaining the dried codonopsis pilosula.
Example 8
A processing method of dried codonopsis pilosula comprises the following steps:
removing the epidermis of fresh codonopsis pilosula, cleaning, draining water on the surface, cutting into slices with the thickness of about 2.5mm, placing the slices in a freeze dryer, stacking the slices with the thickness of less than or equal to 20mm, pre-freezing the slices for 5 hours at the temperature of minus 45 ℃, setting the vacuum degree to be in the range of 76-82 Pa, controlling the temperature to be increased from minus 45 ℃ to 0 ℃ in a staged manner, increasing the temperature to 45 ℃ in a staged manner from 0 ℃ for treatment, selecting the temperature increase rate of 10 ℃/h in two adjacent stages, and automatically drying the codonopsis pilosula; the drying temperature and the treatment time of the specific staged treatment are as follows:
a first stage: -45 ℃ and a temperature of 3h
And (2) second stage: -30 ℃ and a temperature of 3h
And (3) three stages: -25 ℃ at a temperature of 2h
And a fourth stage: -20 ℃ and a temperature of 3h
Five stages: 10 ℃ below zero, temperature 2h
Six sections: 0 ℃ and a temperature of 3h
Seven sections: 10 ℃ at a temperature of 2h45min
Eight sections: at 25 ℃ and a temperature of 3h
Nine sections: 35 ℃ and a temperature of 3h
Ten sections: the temperature is 45 ℃ and 3 h; thus obtaining the dried codonopsis pilosula.
Example 9
A processing method of dried codonopsis pilosula comprises the following steps:
removing epidermis from fresh radix Codonopsis, cleaning, draining water on the surface, cutting into pieces with thickness of about 2.5mm, placing in a freeze dryer, stacking at thickness of less than or equal to 20mm, pre-freezing at-45 deg.C for 5h, setting vacuum degree within 83-88 Pa, controlling temperature from-45 deg.C to 0 deg.C in a staged manner, heating from 0 deg.C to 45 deg.C in a staged manner, selecting heating rate of 10 deg.C/h in two adjacent stages, and automatically drying radix Codonopsis; the drying temperature and the treatment time of the specific staged treatment are as follows:
a first stage: -45 ℃ and a temperature of 3h
And (2) second stage: -30 ℃ and a temperature of 3h
And (3) three stages: -25 ℃ and a temperature of 3h
And a fourth stage: -20 ℃ at a temperature of 2h
Five stages: -10 ℃ at a temperature of 3h
Six sections: 0 ℃ and a temperature of 3h
Seven sections: 10 ℃ at a temperature of 3h
Eight sections: at 25 ℃ and a temperature of 3h
Nine sections: 35 ℃ at a temperature of 2h
Ten sections: the temperature is 3hh25min at 45 ℃; thus obtaining the dried codonopsis pilosula.
Comparative example 1
A method for drying radix Codonopsis comprises the following steps:
cleaning fresh radix Codonopsis, and sun drying to obtain dried radix Codonopsis.
In order to illustrate the relevant performance of the vacuum drying method provided by the invention, the relevant performance of the codonopsis pilosula dried in the examples 1-9 and the comparative example 1 is detected, and the specific detection result is shown in table 1.
The inspection basis is as follows: "Chinese pharmacopoeia" 2020 edition one department
(one) checking moisture
The standard specifies: should not exceed 16.0%.
(II) examination of Total Ash
The standard specifies: should not exceed 5.0%.
(III) examination of acid-insoluble Ash
The standard specifies: should not exceed 2.0%.
(IV) extract
The standard specifies: the content of the extract should not be less than 55.0% by hot dipping method under alcohol-soluble extract measuring method (general rule 2201) with 45% ethanol as solvent.
Table 1 shows the data of the properties of dried Codonopsis pilosula of examples 1-9 and comparative example 1
Examples | Water content/%) | Total ash content% | Extract/% |
1 | 2.2 | 2.5 | 63.9 |
2 | 2.6 | 2.32 | 63.5 |
3 | 5.3 | 2.48 | 63.8 |
4 | 4.6 | 2.53 | 64.0 |
5 | 3.5 | 2.4 | 64.3 |
6 | 4.4 | 2.37 | 63.6 |
7 | 3.1 | 2.25 | 64.4 |
8 | 3.3 | 2.46 | 63.7 |
9 | 5.7 | 2.59 | 64.2 |
Comparative example 1 | 7.9 | 2.6 | 56.5 |
Table 1 shows that the processing method of dried codonopsis pilosula provided by the present invention can maximally keep fresh, avoid increase of ash content and decrease of extract in the process of drying codonopsis pilosula, and the moisture content of codonopsis pilosula dried by the method is far lower than that of codonopsis pilosula obtained by using the existing drying technology, thereby effectively improving the quality of medicinal materials.
The method provided by the invention replaces sulfur fumigation in the traditional processing process of dried codonopsis pilosula products, and the prepared codonopsis pilosula is not easy to lose oil, is non-toxic to human bodies and non-pollution to the environment, and can retain the effective components and curative effects of traditional Chinese medicinal materials to the maximum extent. The method provided by the invention can effectively improve the drying efficiency and reduce the cost of energy consumption by controlling the total drying time to be 20-30 h.
It will be apparent to those skilled in the art that various changes and modifications may be made in the present invention without departing from the spirit and scope of the invention. Thus, it is intended that such changes and modifications be included within the scope of the appended claims and their equivalents.
Claims (6)
1. A processing method of dried codonopsis pilosula is characterized by comprising the following steps:
removing the epidermis of fresh codonopsis pilosula, cleaning, draining water on the surface, pre-freezing at-45 to-35 ℃ for 3-6 hours, placing in a freeze dryer with the vacuum degree of 5-100 Pa, controlling the treatment temperature to be increased from-75 to-30 ℃ to 0 ℃ in a staged manner, then increasing the temperature from 0 ℃ to 40-60 ℃ in a staged manner, and obtaining the dried codonopsis pilosula after the treatment is finished.
2. The processing method of the dried codonopsis pilosula according to claim 1, wherein the temperature is raised from-75 to-30 ℃ to 0 ℃ in a staged manner, the heat preservation treatment is carried out in six stages, the temperature difference between two adjacent stages is 5 to 20 ℃, and the heat preservation time of each stage is 1 to 4 hours; heating from 0 ℃ to 40-60 ℃ in a staged manner, carrying out heat preservation treatment in four stages, wherein the temperature difference between two adjacent stages is 5-20 ℃, and the heat preservation time of each stage is 1-4 hours.
3. The processing method of the dried codonopsis pilosula according to claim 2, wherein the temperature rise rate of two adjacent stages is 5-10 ℃/h.
4. The method for processing the dried codonopsis pilosula according to claim 1, wherein the vacuum degree is 65-88 Pa.
5. The processing method of the dried codonopsis pilosula according to claim 1, wherein the fresh codonopsis pilosula is sliced before being processed, the sliced thickness is 2-3 mm, and the stacking thickness is less than or equal to 20mm when the codonopsis pilosula is placed in a freeze dryer.
6. Dried Codonopsis pilosula prepared by the method of any one of claims 1 to 5.
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CN110538240A (en) * | 2019-10-21 | 2019-12-06 | 广东众生药业股份有限公司 | Freeze-drying processing method of radix scrophulariae |
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CN107296820A (en) * | 2017-06-29 | 2017-10-27 | 黑龙江神守药业有限公司 | A kind of no added lyophilized ginseng class medicinal material |
CN110538240A (en) * | 2019-10-21 | 2019-12-06 | 广东众生药业股份有限公司 | Freeze-drying processing method of radix scrophulariae |
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