CN113144387B

CN113144387B - Guide wire with built-in sliding probe

Info

Publication number: CN113144387B
Application number: CN202110483329.8A
Authority: CN
Inventors: 于波; 康维; 马国娣; 代建南; 赵晨; 徐晨阳
Original assignee: Panorama Scientific Co ltd; Harbin Medical University
Current assignee: Panorama Scientific Co ltd; Harbin Medical University
Priority date: 2021-04-30
Filing date: 2021-04-30
Publication date: 2022-03-08
Anticipated expiration: 2041-04-30
Also published as: CN113144387A

Abstract

The invention discloses a guide wire with a built-in sliding probe, belonging to the field of diagnosis; the guide wire near-end movable section is arranged at the near end of the guide wire wall main body, the far end of the guide wire near-end movable section is integrally and fixedly connected with an extending-in part, the extending-in part is tightly sleeved with the inner wall of the guide wire wall main body, and the optical fiber penetrates through the guide wire near-end movable section and the extending-in part and is fixedly connected with the guide wire near-end movable section; the extending part is in clearance fit with the proximal end of the guide wire wall main body; the top end of the optical fiber is provided with an optical fiber pressure sensor; the far end of the guide wire wall main body is provided with a continuous pressure equalizing groove; an optical fiber moving space is arranged between the guide wire wall main body and the optical fiber. The pressure sensor slides in the guide wire within a certain range, and the pressure in the sliding range is measured through the continuous pressure equalizing grooves on the wall of the guide wire, so that the injury to the vessel wall and the operation time caused by operation are reduced. The area near the far end of the main body of the guide wire wall is provided with the pressure equalizing groove, so that the characteristic that the guide wire wall is more flexible as the guide wire wall is closer to the top end is achieved on the basis of not changing the material of the guide wire wall.

Description

Guide wire with built-in sliding probe

Technical Field

The invention belongs to the technical field of diagnosis, and particularly relates to a guide wire with a built-in sliding probe.

Background

Pressure sensors for pressure guidewires are typically placed at a fixed location at the distal end of the guidewire. When using pressure guidewires for luminal pressure measurements, such as intravascular pressure measurements, physicians often have interest in multipoint pressures. For example, in a diffuse stenotic lesion, a physician may need to measure the pressure distal and proximal to multiple stenoses. This may require repeated pushing and pulling back of the pressure guidewire. It is difficult to push a guidewire in a stenotic vessel, and unnecessary damage to the vessel wall may occur. The invention aims to design a guide wire with a pressure sensor capable of moving axially, and the pressure sensor is moved in the guide wire on the basis of not moving the outer wall of the guide wire, so that multipoint pressure is measured on the basis of reducing pushing and pulling back of the guide wire.

The patent publication US 20140187986a proposes a design in which a number of pressure equalization holes are made in the wall of the guide wire tube, and the pressure can be measured by sliding a pressure sensor near these pressure equalization holes. A problem with this design, however, is that the pressure equalizing holes are only present in discrete fixed locations, which are not necessarily the best locations for measuring pressure.

Aiming at the problem, the invention provides a design scheme of carving continuous pressure equalizing grooves on the wall of the guide wire, so that the sliding pressure sensor can continuously measure pressure within a certain range and has stronger applicability to narrow lesions with different lengths.

Disclosure of Invention

In order to solve the problems in the background art, the invention provides a guide wire with a built-in sliding probe, which is characterized by comprising: the optical fiber pressure sensor comprises a guide wire wall main body, a guide wire near-end movable section, an optical fiber and an optical fiber pressure sensor, wherein the guide wire near-end movable section is arranged at the near end of the guide wire wall main body, the far end of the guide wire near-end movable section is integrally and fixedly connected with an extending part, the extending part is tightly sleeved with the inner wall of the guide wire wall main body, and the optical fiber penetrates through the guide wire near-end movable section and the extending part and is fixedly connected with the guide wire near-end movable section; the extending part is in clearance fit with the proximal end of the guide wire wall main body; the top end of the optical fiber is provided with an optical fiber pressure sensor; the far end of the guide wire wall main body is provided with a continuous pressure equalizing groove; an optical fiber moving space is arranged between the guide wire wall main body and the optical fiber.

The outer diameter of the guide wire wall main body is 356 micrometers, the wall thickness of the far end of the guide wire wall main body is 80 micrometers-100 micrometers, and the thickness of the optical fiber moving space is 10 micrometers-80 micrometers.

The optical fiber is connected with the optical interface at the near end of the guide wire receiver, the optical adapter, the patient interaction unit and the pressure measurement engine in sequence through the optical coupling end face at the near end of the optical fiber.

And a spring head is arranged outside the far end of the guide wire wall main body.

The outer diameters and the materials of the guide wire wall main body and the guide wire proximal end movable section are equal; the near end of the guide wire wall main body and the far end of the guide wire near end movable section are both provided with anti-skid grains.

The pressure equalizing groove is spiral or linear.

The groove width of the pressure equalizing groove is 50-100 micrometers, the length of the pressure equalizing groove in the axial direction is 20-40 millimeters, and the length of the extending part is not less than the length of the pressure equalizing groove in the axial direction.

The groove width of the pressure equalizing groove gradually widens from the proximal end to the distal end.

When the pressure equalizing groove is spiral, the lead of the pressure equalizing groove is gradually shortened from the near end to the far end.

The outer surface of the cladding is wrapped with a buffer layer, the outer diameter of the cladding is 100 micrometers, and the distance between the far end of the buffer layer and the axis of the interference cavity is 0.2-3 millimeters; the thickness of the buffer layer is 60 microns, and the material of the buffer layer is polyamide.

The invention has the beneficial effects that:

1. the pressure sensor is allowed to slide in the guide wire within a certain axial range, and the pressure in the sliding range is measured through the continuous pressure equalizing grooves in the wall of the guide wire. Therefore, the doctor does not need to repeatedly push and pull the blood vessel guide wire, the operation is convenient, and the injury to the blood vessel wall and the operation time are reduced.

2. The pressure equalizing groove is formed in the area near the far end of the main body of the guide wire wall, so that the guide wire wall is made of stainless steel or nickel alloy, the characteristic that the guide wire wall is softer as the guide wire wall is closer to the top end is achieved, blood vessels are prevented from being injured, and the structure of the complex blood vessels can be adapted to.

3. The pressure sensor with smaller cross-sectional dimension is used, and the pressure sensor integrated at the top end of the optical fiber is particularly adopted, so that the cross-sectional area of a lumen for the sensor to slide in the guide wire is as small as possible, the thickness of the guide wire wall is as thick as possible, and the support strength of the guide wire wall is increased.

Drawings

FIG. 1 is a schematic structural view of an embodiment of a guide wire with a sliding probe inside according to the present invention;

FIG. 2 is a partial schematic view of an embodiment of the present invention near the pressure equalization trench;

FIG. 3 is a partial cross-sectional view of an embodiment of the present invention near a pressure equalization trench;

FIG. 4 is a partial schematic view of an embodiment of the present invention near the protrusion.

Wherein: 1-a guide wire wall main body, 2-a guide wire proximal end movable section, 3-an optical fiber, 4-an optical fiber movable space, 5-a main body anti-skid grain, 6-a distal end anti-skid grain, 13-a pressure equalizing groove, 16-a guide wire receiver, 17-an optical adapter, 18-a patient interaction unit, 19-a pressure measuring engine, 21-an extending part, 31-an optical fiber pressure sensor, 33-a cladding, 35-an interference cavity and 36-a buffer layer.

Detailed Description

The present invention will be described in further detail with reference to the accompanying drawings.

The embodiment of the present invention shown in fig. 1 to 4 includes: the device comprises a guide wire wall main body 1, a guide wire near-end movable section 2, an optical fiber 3, a guide wire receiver 16, an optical adapter 17, a patient interaction unit 18, a pressure measurement engine 19 and an optical fiber pressure sensor 31, wherein the guide wire near-end movable section 2 is arranged at the near end of the guide wire wall main body 1, the far end of the guide wire near-end movable section 2 is integrally and fixedly connected with an extending part 21, the extending part 21 is tightly sleeved with the inner wall of the guide wire wall main body 1, and the optical fiber 3 penetrates through the guide wire near-end movable section 2 and the extending part 21 and is fixedly connected with the guide wire near-end movable section 2; the extending part 21 is in clearance fit with the proximal end of the guide wire wall main body 1; the top end of the optical fiber 3 is provided with an optical fiber pressure sensor 31; the optical fiber 3 is connected with an optical coupling end face 15 at the proximal end thereof into an optical interface at the proximal end of a guide wire receiver 16 so as to be sequentially connected with an optical adapter 17, a patient interaction unit 18 and a pressure measurement engine 19;

the region near the near end of the guide wire wall main body 1 is provided with main body anti-skid grains 5, and the far end of the guide wire wall main body 1 is etched by laser to form a continuous pressure equalizing groove 13, so that a doctor can conveniently control the guide wire; an optical fiber moving space 4 with the thickness of about 10-80 microns is arranged between the guide wire wall main body 1 and the optical fiber 3;

the tight sleeving is characterized in that a certain friction force exists between the inner sleeving and the outer sleeving, and the friction force enables a doctor to do the same movement along with the other part (the guide wire wall main body 1 or the guide wire proximal end movable section 2) when independently pushing and pulling the guide wire proximal end movable section 2 or the guide wire wall main body 1. The relative movement of the guide wire wall body 1 and the guide wire proximal end movable section 2 can be realized only when the doctor respectively holds the two parts, so that the doctor can push or pull the pressure sensor at the distal end of the guide wire to a required position.

In the embodiment, the outer diameters and the materials of the guide wire wall main body 1 and the guide wire proximal end movable section 2 are equal; the far end of the guide wire near-end movable section 2 is also provided with far-end anti-skid grains 6;

in this embodiment, a spring head 14 is further installed outside the distal end of the guide wire wall main body 1 to reduce the damage to the blood vessel during the guide wire advancing process and guide the advancing direction of the guide wire;

in this embodiment, the pressure equalizing groove 13 is spiral or linear, the closer the guide wire wall should be to the top, the softer the guide wire wall should be, so as to avoid damaging blood vessels, and meanwhile, the pressure equalizing groove can adapt to complex blood vessel structures; however, the conventional guide wire wall is generally a cylinder made of stainless steel or nickel alloy, and it is difficult to directly change the hardness thereof, so that the spiral pressure equalizing groove 13 is preferable;

in the present embodiment, the guide wire wall body 1 is a blood vessel guide wire with an outer diameter of 356 microns, and the wall thickness of the guide wire wall body 1 at the distal end can be preferably 80 microns to 100 microns.

The pressure equalizing groove 13 shown in fig. 2 is a single spiral to keep the deformation in each radial direction similar when the distal tip of the guide wire is stressed in the radial direction; thereby guarantee to have the biggest groove width under the condition that the seal wire has enough holding power, make things convenient for inside blood gets into the seal wire, form the voltage-sharing. As the guidewire wall body 1 is closer to the tip, it should be softer; therefore, on a spiral basis, the hardness of the catheter wall can be further changed by uniformly shortening the lead of the pressure equalizing groove 13 from the near end to the far end, for example, the hardness can be gradually changed from one period (lead) of rotation of every 10 micrometers at the near end to one period (lead) of rotation of every 5 micrometers at the far end. Meanwhile, the width of the equalizing groove and the number of the rotation cycles of the spiral groove can be changed for use.

In the present embodiment, the groove width of the pressure equalizing groove 13 is preferably 50 to 100 micrometers, and may gradually widen from the proximal end to the distal end.

In the present embodiment, the length covered by the pressure equalizing groove 13 in the axial direction is preferably 20 mm to 40 mm, and this extended length in the axial direction determines the distance range in which the pressure sensor can slide and measure, while the length of the protruding portion 21 is not less than the length of the pressure equalizing groove 13.

The optical sensor generally has an axisymmetric cross-sectional shape, such as a regular hexagon or a circle, to facilitate its movement within a narrow guide wire lumen; the fiber optic pressure sensor 31 shown in fig. 3 is mounted at the distal end of the optical fiber 3 in the following manner: an interference cavity 35 is formed at the top end of the cladding 33 in the optical fiber 3, a diaphragm 34 is fixed outside the flat distal end of the interference cavity 35, and pressure is sensed by the diaphragm 34. The structure is disclosed in US 10,281,348B2, and the optical fiber pressure sensor 31 disclosed in the patent ensures the minimum size of the optical fiber moving space 4 on the basis of ensuring the thickness of the guide wire wall, i.e. ensuring the free movement of the optical fiber 3 and ensuring that the far end of the guide wire wall main body 1 can provide enough support;

in this embodiment, the optical fiber 3 is a single mode optical fiber, and the outer diameter of the cladding 33 is 100 μm;

in this embodiment, the cladding 33 of the optical fiber 3 is externally wrapped with the buffer layer 36 to fill the optical fiber active space 4; the distance between the far end of the buffer layer 36 and the axis of the interference cavity 35 is 0.2-3 microns; the thickness of buffer layer 36 is 60 microns and the material of buffer layer 36 is polyamide.

When in use, the utility model is used for cleaning the inner wall of the tank,

pushing the guide wire proximal end movable section 2 or the guide wire wall main body 1 to push the guide wire wall main body 1 to a specified position, and then connecting the optical coupling end face 15 into the guide wire receiver 16;

the pressure on the periphery is transmitted to the optical fiber pressure sensor 31 in the guide wire through the pressure equalizing groove, and after the optical fiber pressure sensor 31 generates signals, the signal transmission is completed through the optical fiber in the guide wire cavity.

After the pressure collection of one part is finished, the guide wire proximal end active section 2 is gradually pulled out to change the position of the optical fiber pressure sensor 31, so that the optical fiber 3 and the optical fiber pressure sensor 31 which move synchronously (axially or circumferentially) with the guide wire proximal end active section 2 complete the pressure collection work of different positions.

After all pressure collection work is finished, the guide wire wall main body 1 is held tightly, and the guide wire proximal end movable section 2 is pushed at the same time, so that the extending part 21 completely returns to the guide wire wall main body 1; the guide wire wall body 1 is then withdrawn by simultaneously pulling the guide wire wall body 1 and the guide wire receiver 16.

Claims

1. A guidewire with a built-in sliding probe, comprising: guide wire wall main part (1), guide wire near-end activity section (2), optic fibre (3) and optic fibre pressure sensor (31), wherein optic fibre pressure sensor (31) are installed to the top of optic fibre (3), and the mounting means is: an interference cavity (35) is manufactured at the top end of a cladding (33) in the optical fiber (3), a diaphragm (34) is fixedly connected outside the flat far end of the interference cavity (35), and pressure is sensed through the diaphragm (34); the device is characterized in that the guide wire near-end movable section (2) is arranged at the near end of the guide wire wall main body (1), the far end of the guide wire near-end movable section (2) is integrally and fixedly connected with an extending part (21), the extending part (21) is tightly sleeved with the inner wall of the guide wire wall main body (1), and the optical fiber (3) penetrates through the guide wire near-end movable section (2) and the extending part (21) and is fixedly connected with the guide wire near-end movable section (2); the extending part (21) is in clearance fit with the proximal end of the guide wire wall main body (1); the far end of the guide wire wall main body (1) is provided with a continuous pressure equalizing groove (13), and the length of the pressure equalizing groove (13) in the axial direction is 20-40 mm; an optical fiber moving space (4) is arranged between the guide wire wall main body (1) and the optical fiber (3), so that the pressure sensor slides in the guide wire within a certain axial range, and the pressure in the sliding range is measured through the continuous pressure equalizing grooves on the guide wire wall.

2. The guide wire with the built-in sliding probe according to claim 1, wherein the outer diameter of the guide wire wall main body (1) is 356 micrometers, the wall thickness of the far end of the guide wire wall main body (1) is 80 micrometers to 100 micrometers, and the thickness of the optical fiber moving space (4) is 10 micrometers to 80 micrometers.

3. A guide wire with a built-in sliding probe according to claim 1, characterized in that the optical fiber (3) is connected with the optical coupling end face (15) at the proximal end thereof to the optical interface at the proximal end of the guide wire receiver (16), the optical adapter (17), the patient interaction unit (18) and the pressure measurement engine (19) in sequence.

4. A guide wire with a built-in sliding probe according to claim 1, characterized in that the spring head (14) is mounted outside the distal end of the guide wire wall body (1).

5. The guide wire with the built-in sliding probe is characterized in that the outer diameter and the material of the guide wire wall main body (1) and the guide wire proximal end movable section (2) are equal; the near end of the guide wire wall main body (1) and the far end of the guide wire near end movable section (2) are both provided with anti-skid grains (5).

6. A guide wire with a built-in sliding probe according to claim 1, wherein the pressure equalizing groove (13) is spiral or linear.

7. The guide wire with the built-in sliding probe is characterized in that the groove width of the pressure equalizing groove (13) is 50-100 micrometers, and the length of the extending part (21) is not less than the length of the pressure equalizing groove (13) in the axial direction.

8. A guide wire with a built-in sliding probe according to any one of claims 6 or 7, wherein the width of the pressure equalizing groove (13) becomes gradually wider from the proximal end to the distal end.

9. A guide wire with a built-in sliding probe according to any one of claims 6 or 7, wherein when the pressure equalizing groove (13) is helical, the lead of the pressure equalizing groove (13) is gradually reduced from the proximal end to the distal end.

10. The guide wire with the built-in sliding probe is characterized in that the cladding (33) is externally wrapped with the buffer layer (36), the outer diameter of the cladding (33) is 100 micrometers, and the distance between the far end of the buffer layer (36) and the axis of the interference cavity (35) is 0.2-3 mm; the thickness of the buffer layer (36) is 60 microns, and the material of the buffer layer (36) is polyamide.