CN113069378A - Moisturizing lotion and preparation method thereof - Google Patents
Moisturizing lotion and preparation method thereof Download PDFInfo
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- CN113069378A CN113069378A CN202010015860.8A CN202010015860A CN113069378A CN 113069378 A CN113069378 A CN 113069378A CN 202010015860 A CN202010015860 A CN 202010015860A CN 113069378 A CN113069378 A CN 113069378A
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- 230000003020 moisturizing effect Effects 0.000 title claims abstract description 42
- 239000006210 lotion Substances 0.000 title claims abstract description 20
- 238000002360 preparation method Methods 0.000 title abstract description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 30
- BIVBRWYINDPWKA-VLQRKCJKSA-L Glycyrrhizinate dipotassium Chemical compound [K+].[K+].O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@H]1CC[C@]2(C)[C@H]3C(=O)C=C4[C@@H]5C[C@](C)(CC[C@@]5(CC[C@@]4(C)[C@]3(C)CC[C@H]2C1(C)C)C)C(O)=O)C([O-])=O)[C@@H]1O[C@H](C([O-])=O)[C@@H](O)[C@H](O)[C@H]1O BIVBRWYINDPWKA-VLQRKCJKSA-L 0.000 claims abstract description 12
- 241001506047 Tremella Species 0.000 claims abstract description 11
- 229940101029 dipotassium glycyrrhizinate Drugs 0.000 claims abstract description 11
- 229920002385 Sodium hyaluronate Polymers 0.000 claims abstract description 10
- 229940064064 purslane extract Drugs 0.000 claims abstract description 10
- 229940010747 sodium hyaluronate Drugs 0.000 claims abstract description 10
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims abstract description 10
- 239000000284 extract Substances 0.000 claims abstract description 9
- 150000004676 glycans Chemical class 0.000 claims abstract description 7
- 229920001282 polysaccharide Polymers 0.000 claims abstract description 7
- 239000005017 polysaccharide Substances 0.000 claims abstract description 7
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 claims abstract description 6
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 claims abstract description 6
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 claims abstract description 6
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims abstract description 5
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims abstract description 5
- 239000011734 sodium Substances 0.000 claims abstract description 5
- 229910052708 sodium Inorganic materials 0.000 claims abstract description 5
- 239000004480 active ingredient Substances 0.000 claims abstract description 4
- 238000003756 stirring Methods 0.000 claims description 15
- 238000001816 cooling Methods 0.000 claims description 8
- 238000006243 chemical reaction Methods 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 6
- 239000013543 active substance Substances 0.000 claims description 5
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims description 4
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 claims description 3
- 238000010438 heat treatment Methods 0.000 claims description 3
- 238000000034 method Methods 0.000 claims description 3
- 229960005323 phenoxyethanol Drugs 0.000 claims description 3
- 239000002994 raw material Substances 0.000 claims description 3
- 239000004471 Glycine Substances 0.000 claims description 2
- 229960002449 glycine Drugs 0.000 claims description 2
- 239000000843 powder Substances 0.000 claims description 2
- 239000002344 surface layer Substances 0.000 claims description 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims 1
- 229920002674 hyaluronan Polymers 0.000 claims 1
- 229960003160 hyaluronic acid Drugs 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000000638 solvent extraction Methods 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 5
- 230000037303 wrinkles Effects 0.000 abstract description 5
- 201000004624 Dermatitis Diseases 0.000 abstract description 4
- 239000002537 cosmetic Substances 0.000 abstract description 3
- 230000004054 inflammatory process Effects 0.000 abstract description 3
- 238000010521 absorption reaction Methods 0.000 abstract description 2
- 230000002950 deficient Effects 0.000 abstract description 2
- 238000009499 grossing Methods 0.000 abstract description 2
- 230000036541 health Effects 0.000 abstract description 2
- 230000035790 physiological processes and functions Effects 0.000 abstract description 2
- 230000009759 skin aging Effects 0.000 abstract description 2
- 229940083542 sodium Drugs 0.000 abstract description 2
- 230000008961 swelling Effects 0.000 abstract description 2
- 208000024891 symptom Diseases 0.000 abstract description 2
- 241000196324 Embryophyta Species 0.000 abstract 1
- 230000006872 improvement Effects 0.000 description 7
- 238000012360 testing method Methods 0.000 description 4
- 238000011156 evaluation Methods 0.000 description 3
- 230000000172 allergic effect Effects 0.000 description 2
- 208000010668 atopic eczema Diseases 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 230000000887 hydrating effect Effects 0.000 description 2
- 239000003755 preservative agent Substances 0.000 description 2
- 230000002335 preservative effect Effects 0.000 description 2
- KIUKXJAPPMFGSW-YXBJCWEESA-N (2s,4s,5r,6s)-6-[(2s,3r,5s,6r)-3-acetamido-2-[(3s,4r,5r,6r)-6-[(3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H](C(O[C@@H]3[C@@H]([C@@H](O)C(O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)C(C(O)=O)O1 KIUKXJAPPMFGSW-YXBJCWEESA-N 0.000 description 1
- XEFAJZOBODPHBG-UHFFFAOYSA-N 1-phenoxyethanol Chemical compound CC(O)OC1=CC=CC=C1 XEFAJZOBODPHBG-UHFFFAOYSA-N 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 1
- 206010042496 Sunburn Diseases 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 239000008367 deionised water Substances 0.000 description 1
- 229910021641 deionized water Inorganic materials 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000003301 hydrolyzing effect Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 238000011056 performance test Methods 0.000 description 1
- 239000000419 plant extract Substances 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 230000037380 skin damage Effects 0.000 description 1
- 230000037394 skin elasticity Effects 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 230000035882 stress Effects 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 238000003809 water extraction Methods 0.000 description 1
- 238000004383 yellowing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/733—Alginic acid; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/004—Aftersun preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Cosmetics (AREA)
Abstract
The invention relates to the field of cosmetics, and particularly relates to moisturizing lotion and a preparation method thereof. The moisturizing water mainly comprises the following components: tremella extract, purslane extract, dipotassium glycyrrhizinate, sodium hyaluronate and sodium trehalose sulfate. The active ingredients have high moisturizing and moisturizing effects, are derived from plants, are safe and effective, and tremella polysaccharide molecules have extremely strong water-locking and moisturizing performances, play a role in high-efficiency moisturizing and skin-care, are fresh and cool, are not sticky, have good water absorption performance and excellent film forming performance, and give the skin a moist, silky and smooth feeling; the dipotassium glycyrrhizinate and the purslane extract can relieve dry red swelling and pain symptoms of calmed and sunburned skin or extremely water-deficient skin, resist skin allergy and inflammation, and can also delay skin aging. The high-content sodium hyaluronate has the effects of moisturizing, moistening and smoothing skin, being fine, smooth, tender and elastic, preventing wrinkles, resisting wrinkles, beautifying, protecting health and recovering physiological functions of skin, and can effectively replenish water and moisturize.
Description
Technical Field
The invention relates to the field of cosmetics, and particularly relates to moisturizing lotion and a preparation method thereof.
Background
With the pressure of urban life, the pace is accelerated, the climate environment changes, the work intensity is high, overtime, staying up all night, fatigue, unreasonable diet and the like, the water shortage condition of the skin is aggravated. Particularly in extreme weather, the stress on the skin is greater. Lack of water in the skin can result in dryness/yellowing/dullness, and the skin tends to be tight. If the skin becomes severe, the skin can be flaccid and wrinkles can be caused. In particular, fine wrinkles and fat particles appear around the eye and the nose. People today are increasingly paying attention to personal care and care. The skin has sufficient moisture, so that the skin is tender and smooth and has full elasticity. However, the moisturizing and hydrating products on the market at present are various in types and have different qualities. In the face of the market demand and the current product situation, a portable, convenient to use and effective skin moisturizing lotion is needed to meet the demand.
Disclosure of Invention
The invention provides the moisturizing lotion and the preparation method thereof, the formula of the moisturizing lotion is precise and reasonable, the functions are practical and effective, the moisturizing lotion is easy to absorb, and meanwhile, the preparation method of the high-efficiency moisturizing lotion is simple, and the moisturizing lotion can resist allergy, relieve and calm skin damage after sunburn. The invention also aims to provide a preparation method of the moisturizing water.
In order to achieve the first object, the invention adopts the following design scheme:
the moisturizing water comprises the following components in percentage by mass:
preferably, the composition comprises the following components in percentage by mass:
preferably, the composition comprises the following components in percentage by mass:
as preferred sodium hyaluronate: the molecular weight of the sodium hyaluronate is 1000KDa, and a breathable film can be formed on the surface layer of the skin to lock water and tighten the skin, and the percentage of the sodium hyaluronate reaches 0.15-0.3%.
The tremella polysaccharide extract is preferably obtained by a boiling water extraction method, the content of active substances reaches 20%, and the percentage of the tremella polysaccharide extract is 4% -8%.
Preferably, the purslane extract is extracted by adopting a solvent and hydrolytic enzyme enzymolysis, so that high-purity active substance components are obtained, and the percentage of the composition is 2-5%.
Preferably, the dipotassium glycyrrhizinate is white powder, wherein the mass fraction of the dipotassium glycyrrhizinate is more than 98%, and the dipotassium glycyrrhizinate has special effects on inflammation and allergic skin caused by sunshine.
The moisturizing water can also contain 0.26-0.35% of preservative.
In order to achieve the second object, the invention adopts the following technical scheme:
a method for preparing the moisturizing water, which comprises the following steps:
1) adding water, sodium hyaluronate, sodium trehalose sulfate and other raw materials into a reaction pot, starting stirring, heating to 75-80 ℃, and preserving heat for 10-15 minutes;
2) cooling circulating water is started, stirring and cooling are carried out, when the temperature is reduced to 45-50 ℃, active ingredients such as tremella extract, purslane extract, dipotassium glycyrrhizinate, glycine and the like are added into a reaction pot, and finally phenoxyethanol is added, and stirring and dissolving are carried out completely;
3) and (4) continuing stirring and cooling to below 40 ℃, stopping stirring, and ending.
The tremella polysaccharide molecules have extremely strong water-locking and moisture-preserving performance, play a role in high-efficiency moisture-preserving and skin-protecting, are fresh and non-sticky, have good water absorption performance and excellent film-forming property, and endow the skin with a moist, silky and smooth feeling
The dipotassium glycyrrhizinate and the purslane extract can relieve dry red swelling and pain symptoms of calmed and sunburned skin or extremely water-deficient skin, resist skin allergy and inflammation, and can also delay skin aging.
The high-content sodium hyaluronate has the effects of moisturizing, moistening and smoothing skin, being fine, smooth, tender and elastic, preventing wrinkle, beautifying and protecting health, and recovering physiological functions of skin
Detailed Description
The moisturizing lotion provided by the invention is prepared from tremella extract, purslane extract, dipotassium glycyrrhizinate, sodium hyaluronate and sodium trehalose sulfate serving as main active ingredients, and is supplemented with a moisturizing agent, a thickening agent, a preservative, a plant extract and water which are common matrix ingredients for cosmetics. The present invention will be described below with reference to some specific examples, but the present invention is not limited thereto.
Detailed Description
Example 1
Moisturizing water:
the components and percentage contents of the components of the moisturizing water are as follows:
| component (%) | Example 1 | Example 2 | Example 3 | Example 4 | Example 5 |
| Tremella extract | 4 | 6 | 5 | 3 | 3 |
| Hyaluronic acid sodium salt | 0.2 | 0.1 | 0.15 | 0.1 | 0.15 |
| Purslane extract | 3 | 2.5 | 3 | 2 | 1.5 |
| Glycyrrhizic acid dipotassium salt | 0.1 | 0.12 | 0.15 | 0.1 | 0.12 |
| Trehalose sodium sulfate | 1 | 0.5 | 0.8 | 0.5 | 0.1 |
| Phenoxyethanol | 0.35 | 0.35 | 0.35 | 0.35 | 0.35 |
| Deionized water | Balance of | Balance of | Balance of | Balance of | Balance of |
The preparation method of the moisturizing water comprises the following steps: adding water, sodium hyaluronate, sodium trehalose sulfate and other raw materials into a reaction pot, starting stirring, heating to 80-85 ℃, and preserving heat for 10-15 minutes; cooling circulating water is started, stirring is carried out, the temperature is reduced, when the temperature is reduced to 45-50 ℃, active substance components such as tremella extract, purslane extract, dipotassium glycyrrhizinate and the like are added into a reaction pot, and finally phenoxyethanol is added, and stirring and dissolving are carried out completely; and (4) continuing stirring and cooling to below 40 ℃, stopping stirring, and ending.
The present invention is not limited to the above-described embodiments, which are described in the specification and illustrated only for illustrating the principle of the present invention, but various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which are also within the scope of the present invention as claimed. The scope of the invention is not to be defined by the appended claims and their equivalents.
Example 3 evaluation of Effect
The moisturizing water provided in example 3 was selected for clinical trials
In order to verify that the product is subjected to performance test in moist water, 150 volunteers are selected for effectiveness test, 150 volunteers are female, healthy people are 28-50 years old, 30 people are randomly divided into 5 groups, and the product of example 3 is used in experimental groups 1-3. Controls 4-5 did not use moisturizing products. The test period is 2 weeks, the moisturizing lotion is used once a day in the morning and at night, the moisturizing lotion is sprayed on the face by 2-3 times of pressing with a spray bottle, the face area is tapped, each user is periodically tracked and investigated, the skin moisture, skin elasticity and skin oil content are detected by a skin tester (Callegari Soft Plus, Italy), the improvement efficacy of the product on the skin of a human body is evaluated, and the evaluation results are shown in the following table (the average value of each group of test results).
Information acquisition: the mean values of the skin parameters at the beginning of the experiment (D0), the mean value of the skin parameters at 7 days from the start of the experiment (D7), and the mean value of the skin parameters at 14 days (D14) were recorded for each group of volunteers, respectively, and the difference between the mean values of the skin parameters for two time periods (D7-D0; D14-D7) was calculated.
TABLE 1. example 3 efficacy test results for insulating water
Note: "+" and "-" represent increases and decreases in the respective values.
The data in the table show that the moisturizing lotion can effectively improve the moisture content and the elasticity value of the skin, and has no allergic side effect. The long-term use can effectively improve the sub-health state of the skin.
Volunteer self-evaluation
The improvement is remarkable: the skin of the tested person is moist and compact, tender and smooth, the pores are reduced, and the satisfaction is high.
Slight improvement: the skin of the subject is slightly improved, no obvious moisture and elasticity change exists, and the satisfaction degree is general.
No improvement: the skin of the subject is not improved, coarse and dry, and the satisfaction is low.
89% of subjects had significant improvement from the skin condition, 9% had slight improvement from the skin condition, and 2% had no improvement from the skin condition.
In conclusion, the moisturizing aquatic product has remarkable moisturizing and hydrating effects.
Claims (8)
1. The moisturizing water is characterized by comprising the following components in percentage by mass:
2. a moisturizing lotion according to claim 1, characterized in that the composition comprises, in mass%:
3. a moisturizing lotion according to claim 1, characterized in that the composition comprises, in mass%:
4. the moisturizing lotion as claimed in claim 1, 2 or 3, wherein the tremella polysaccharide extract has a polysaccharide content of up to 20%. The mass fraction of active substances is more than 90%.
5. The moisturizing lotion as claimed in claim 1, 2 or 3, wherein the hyaluronic acid has a molecular weight of 1000kDa, and can form a breathable film on the surface layer of skin to lock water and tighten skin, and the percentage thereof is 0.15-0.3%.
6. The moisturizing lotion as claimed in claim 1, 2 or 3, wherein the purslane extract is extracted by solvent extraction and enzymolysis with hydrolase to obtain high-purity active substance components, and the percentage of the composition is 2-5%.
7. The moisturizing lotion as claimed in claim 1, 2 or 3, wherein the dipotassium glycyrrhizinate is white powder with a content of more than 98%.
8. A method for producing the moisturizing water of any one of claims 1 to 7. The method is characterized by comprising the following steps:
1) adding water, sodium hyaluronate, sodium trehalose sulfate and other raw materials into a reaction pot, starting stirring, heating to 75-80 ℃, and preserving heat for 10-15 minutes;
2) cooling circulating water is started, stirring and cooling are carried out, when the temperature is reduced to 45-50 ℃, active ingredients such as tremella polysaccharide extract, purslane extract, dipotassium glycyrrhizinate, glycine and the like are added into a reaction pot, and finally phenoxyethanol is added, and stirring and dissolving are carried out completely;
3) and (4) continuing stirring and cooling to below 40 ℃, stopping stirring, and ending.
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| CN115670968A (en) * | 2022-10-31 | 2023-02-03 | 梅晔生物医药股份有限公司 | Composition and daily chemical product with anti-inflammatory and allergy-relieving effects |
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| CN115670968A (en) * | 2022-10-31 | 2023-02-03 | 梅晔生物医药股份有限公司 | Composition and daily chemical product with anti-inflammatory and allergy-relieving effects |
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