CN113018410A - Composition for treating cervical syndrome and preparation method thereof - Google Patents

Composition for treating cervical syndrome and preparation method thereof Download PDF

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Publication number
CN113018410A
CN113018410A CN202110350474.9A CN202110350474A CN113018410A CN 113018410 A CN113018410 A CN 113018410A CN 202110350474 A CN202110350474 A CN 202110350474A CN 113018410 A CN113018410 A CN 113018410A
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parts
composition
wine
cervical syndrome
pain
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李胜平
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
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    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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Abstract

The invention provides a composition for treating cervical syndrome and a preparation method thereof, and relates to the technical field of traditional Chinese medicines. The composition can rapidly penetrate through skin surface, penetrate into subcutaneous tissue and mucous membrane, and enter blood circulation system to achieve good relieving and treating effects. In addition, the composition mainly comprises epimedium and musk, and is supplemented with notopterygium root, asarum, myrrh, angelica, turmeric and safflower, so that the composition can effectively treat symptoms such as limb weakness, waist and knee weakness, difficult walking and the like. Because the composition is prepared from ligusticum wallichii, rhizoma cyperi, clove, rheum officinale and poria cocos, the composition can effectively treat symptoms such as dizziness, vomiting, migraine and the like. In addition, the ginger can promote the qi and blood circulation and the meridian passage, promote the composition to quickly take effect, quickly take effect and relieve the pain of patients. In addition, the preparation method of the composition is simple and easy to implement, the preparation period is short, and the automation is easy to realize.

Description

Composition for treating cervical syndrome and preparation method thereof
Technical Field
The invention relates to the technical field of traditional Chinese medicines, and particularly relates to a composition for treating cervical syndrome and a preparation method thereof.
Background
The cervical syndrome is also called cervical spondylosis, and a series of clinical syndromes of dysfunction mainly caused by long-term strain of cervical vertebra, hyperosteogeny or lumbar intervertebral disc protrusion are clinically manifested as neck and back pain, weakness of upper limbs, numbness of fingers, hypodynamia of lower limbs, difficulty in walking, dizziness, nausea, vomiting and the like. Moreover, some causes inducing cervical syndrome are easily overlooked, such as poor sleeping posture, improper working posture and improper physical exercise, which increases the probability of suffering cervical syndrome. In addition, the symptoms of neck and back pain, limb weakness, walking difficulty, dizziness and the like caused by cervical syndrome can seriously affect the working efficiency and the rest state of the patient, if the symptoms can not be relieved and treated in time, the patient can be in a state of enduring the pain for a long time, and the normal life is affected. Therefore, the development of a composition that can treat the condition can effectively alleviate the suffering of the patient.
Disclosure of Invention
The invention aims to provide a composition for treating cervical syndrome, which has reasonable compatibility and better treatment effect on symptoms such as limpness, weakness, difficulty in walking, headache, dizziness, nausea and the like caused by the cervical syndrome.
The invention also aims to provide a preparation method of the composition for treating cervical syndrome, which is simple and feasible, has short preparation period and is easy to realize automation.
The technical problem to be solved by the invention is realized by adopting the following technical scheme.
On one hand, the invention provides a composition for treating cervical syndrome, which comprises the following raw materials in parts by weight: 15-30 parts of notopterygium root, 15-30 parts of rhubarb, 15-30 parts of clove, 15-30 parts of asarum, 20-40 parts of myrrh, 20-40 parts of angelica, 25-45 parts of rhizoma cyperi, 40-60 parts of turmeric, 40-60 parts of safflower, 75-105 parts of ligusticum wallichii, 75-110 parts of pseudo-ginseng, 135-165 parts of epimedium, 495-505 parts of musk, 495-505 parts of poria cocos and 4000-6000 parts of ginger.
On the other hand, the invention provides a preparation method of a composition for treating cervical syndrome, which comprises the following steps:
soaking Capsici fructus in wine, removing Capsici fructus to obtain Capsici fructus wine; pulverizing the raw materials except Capsici fructus, wine and oleum Rapae to obtain pulverized material, adding Capsici fructus wine and oleum Rapae, mixing, and making into unguent.
The composition for treating cervical syndrome and the preparation method thereof provided by the embodiment of the invention have at least the following beneficial effects:
the embodiment of the invention provides a composition for treating cervical syndrome, which has better curative effects on symptoms such as pain, limb weakness, difficulty in walking, dizziness, nausea and the like caused by the cervical syndrome. Specifically, the composition can rapidly permeate through the skin surface, permeate to subcutaneous tissues and mucous membranes and enter a blood circulation system, so that better relieving and treating effects are achieved. The composition contains epimedium and musk, so the composition has good treatment effect on symptoms such as limb weakness, walking difficulty, weakness of waist and knees and the like, and is supplemented with notopterygium root, asarum, myrrh, angelica, turmeric and safflower, so the composition not only can further relieve the symptoms such as limb weakness, weakness of waist and knees, walking difficulty and the like, but also has certain relieving effect on headache and dizziness. Moreover, the medicine has good treatment effect on symptoms such as rheumatism, arthritis and the like. The compatibility of the ligusticum wallichii and the rhizoma cyperi in the composition can effectively treat headache, and the composition can effectively treat symptoms such as dizziness, vomiting, headache and the like caused by cervical syndrome because the composition contains the clove, the rheum officinale and the poria cocos. The ginger in the composition has the effects of relieving and eliminating body pain and headache, and can also enhance the penetration and absorption effects of the composition, so that the effective components of the medicine can quickly enter a blood circulation system, the effect of promoting qi and blood circulation is achieved, the effects of expelling cold, clearing damp, clearing and activating the channels and collaterals are also achieved, the composition can quickly exert the effect, the treatment effect is achieved, and the pain of a patient is relieved. Moreover, the capsaicin and the alcohol contained in the composition can expand blood vessels of affected parts of patients, and further promote local blood circulation and medicine application, so that the composition has quick and good treatment effect. In addition, the preparation method of the composition is simple and easy to implement, the preparation period is short, and the automation is easy to realize.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below. The examples, in which specific conditions are not specified, were conducted under conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are not indicated by the manufacturer, and are all conventional products available commercially.
It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict. The present invention will be described in detail below with reference to specific examples.
The invention provides a composition for treating cervical syndrome, which comprises the following raw materials in parts by weight: 15-30 parts of notopterygium root, 15-30 parts of rhubarb, 15-30 parts of clove, 15-30 parts of asarum, 20-40 parts of myrrh, 20-40 parts of angelica, 25-45 parts of rhizoma cyperi, 40-60 parts of turmeric, 40-60 parts of safflower, 75-105 parts of ligusticum wallichii, 75-110 parts of pseudo-ginseng, 135-165 parts of epimedium, 495-505 parts of musk, 495-505 parts of poria cocos and 4000-6000 parts of ginger.
Wherein, the epimedium and the musk have obvious effect on treating symptoms such as weakness of upper limbs, hypodynamia of lower limbs, soreness and weakness of waist and knees, difficult walking and the like. Specifically, herba Epimedii enters liver and kidney meridians, has effects of invigorating kidney, tonifying yang, dispelling pathogenic wind and removing dampness, and can be used for treating sexual impotence, dribbling urination, spasm and spasm of tendons and bones, hemiplegia, weakness of waist and knees, rheumatalgia, and limb numbness. Moreover, herba Epimedii also has sedative, antibacterial, antiinflammatory and antiviral effects. Moschus has effects of inducing resuscitation, promoting blood circulation, dredging channels, relieving swelling and pain, and can be used for treating block pattern of coma, pyocutaneous disease, toxic swelling, abdominal mass, heart and abdomen pain, headache, traumatic injury, and arthralgia due to wind-cold-dampness. In addition, musk also has certain anti-inflammatory effect, and the anti-inflammatory effect is similar to that of hydrocortisone. Therefore, the composition has a good treatment effect on symptoms such as myasthenia of limbs, soreness and weakness of waist and knees, difficulty in walking and the like caused by cervical syndrome, and also has a certain anti-inflammatory and bacteriostatic effects, so that the composition can be used for skin affected parts with symptoms such as erythema, erythema and the like, and has stronger applicability. Based on the efficacy of the medicine, the composition also has good treatment effect on symptoms such as rheumatism, arthritis and the like, for example, the composition has good effect on rheumatic arthralgia, osteodynia, joint swelling and pain and the like caused by rheumatism.
Moreover, when the notopterygium root, the asarum, the myrrh, the angelica, the turmeric and the safflower are supplemented, the composition has the effects of clearing and activating the channels and collaterals, promoting blood circulation to remove blood stasis and relieving pain, not only can further enhance the treatment effect on the symptoms of weakness of limbs, soreness and weakness of waist and knees, difficulty in walking and the like, but also has certain relieving and treating effects on symptoms of body pain (such as neck, shoulder, waist and back pain), headache, dizziness and the like caused by cervical syndrome. Specifically, Notopterygium root, rhizoma et radix Notopterygii, being pungent and bitter in taste and warm in nature, can relieve exterior syndrome, dispel cold and dampness, and is mainly used for treating wind-cold type common cold, wind-cold type arthralgia, neck rigidity and spasm, bone joint soreness and pain, edema due to wind-cold, carbuncle, deep-rooted carbuncle and sore-toxin. The asarum has pungent taste, warm nature and little toxicity, has the effects of relieving exterior syndrome, dispelling cold, dispelling wind and relieving pain, dredging orifices, warming lung and resolving fluid retention, and has better curative effects on wind-cold type common cold, headache, toothache, rheumatic arthralgia, nasosinusitis and cough due to lung cold. Myrrha is pungent, bitter and neutral in flavor, has effects of removing blood stasis, relieving pain, subsiding swelling and promoting granulation, and can be used for treating thoracic obstruction, cardialgia, epigastric pain, abdominal pain, rheumatalgia, traumatic injury, carbuncle, swelling, and pyocutaneous disease. Radix Angelicae sinensis is sweet and pungent in flavor and warm in nature, has effects in replenishing blood, promoting blood circulation, regulating menstruation, relieving pain, and loosening bowel to relieve constipation, and can be used for treating blood deficiency, sallow complexion, giddiness, cardiopalmus, asthenia cold abdominal pain, rheumatalgia, traumatic injury, carbuncle, skin ulcer, etc. Moreover, when the wine angelica is used, the wine angelica has obvious effects of activating blood and stimulating menstrual flow and has better treatment effect on rheumatic arthralgia and traumatic injury. Curcuma rhizome has effects of removing blood stasis, activating qi-flowing, dredging channels and relieving pain, and can be used for treating pricking pain in chest and hypochondrium, thoracic obstruction, cardialgia, dysmenorrhea, amenorrhea, abdominal mass, rheumatism shoulder and arm pain and traumatic injury swelling and pain. Carthami flos has effects of promoting blood circulation, dredging channels, removing blood stasis and relieving pain, and can be used for treating lochia, abdominal mass, thoracic obstruction, cardialgia, stagnation of blood, abdominal pain, pricking pain in chest and hypochondrium, traumatic injury, and pyocutaneous disease with swelling and pain. Therefore, the composition has the efficacy of detumescence and tissue regeneration because of the matching of the medicines, so that the composition can be used for sensitive skin affected parts. In addition, the medicine can treat headache caused by rheumatism, and has good effect and strong practicability.
In the embodiment of the invention, the composition also contains the medicine pseudo-ginseng, and has the effects of removing blood stasis, stopping bleeding, reducing swelling and relieving pain. Specifically, Notoginseng radix is warm in nature, enters liver and stomach meridians, and can be used for hemoptysis, hematemesis, epistaxis, hematochezia, traumatic hemorrhage, thoracico-abdominal pain and traumatic swelling and pain. Therefore, due to the effect of the pseudo-ginseng, when a patient applies the composition externally, the patient can effectively relieve the pain, and the effects of detumescence and stasis removal are obvious, and moreover, the composition can also be used for an affected part with a wound to play a role in stopping bleeding in time.
In the embodiment of the invention, aiming at symptoms such as dizziness, vomit, dizziness, migraine and the like caused by cervical syndrome, the composition is prepared from tuckahoe, rhubarb, clove, rhizoma cyperi and ligusticum wallichii, and can effectively relieve symptoms such as the headache and the dizziness. Specifically, the poria cocos is selected from dried sclerotium of fungi as a medicine part, has neutral nature, enters heart, lung, spleen and kidney channels, has the effects of promoting diuresis, eliminating dampness, strengthening spleen and calming heart, and is used for treating edema, oliguria, phlegm and fluid retention, dizziness and palpitation, spleen deficiency, poor appetite, loose stool and diarrhea, uneasiness, palpitation and insomnia. Rhubarb, being cold in nature, enters stomach, large intestine and liver meridians, has the effects of purging heat toxin, breaking food stagnation and removing blood stasis, and can be used for treating excess heat constipation, tenesmus, abdominal mass, sudden red and pain eyes, hematemesis, epistaxis, yellow yang, edema, stranguria with turbid urine and carbuncle and ulcer pyogenic infections. Flos Caryophylli is warm in nature, has effects of warming middle energizer, lowering adverse qi, invigorating kidney, and tonifying yang, and can be used for treating deficiency cold of spleen and stomach, singultus emesis, anorexia, vomiting and diarrhea, cold pain of heart and abdomen, sexual impotence due to kidney deficiency, injury, and swelling and pain. The product has mild flavor and special flavor, and can enter liver, spleen and triple energizer meridians, and has effects in dispersing stagnated liver qi, relieving qi stagnation, regulating qi-flowing, relieving epigastric distention, regulating menstruation, and relieving pain, and can be used for treating stagnation of qi due to liver depression, distending pain in chest and hypochondrium, hernia pain, stagnation of qi in spleen and stomach, and distention and pain. Rhizoma Ligustici Chuanxiong is warm in nature, has effects of activating qi-flowing, resolving stagnation, dispelling pathogenic wind, eliminating dampness, promoting blood circulation and relieving pain, and can be used for treating wind-cold headache, dizziness, hypochondriac pain, abdominal pain, cold arthralgia, spasm of tendons, carbuncle, skin and external diseases, pain in chest and hypochondrium, traumatic injury, swelling and pain, headache and rheumatism pain. Moreover, the Benjing shows that the chuanxiong rhizome can be used together with the above-mentioned herbs of cyperus tuber, asarum herb and notopterygium root to treat wind attacking upwards, dizziness, migraine, headache, restless limbs, muscular wriggle, pain in temple and wind-induced qi, etc., with better curative effect. And the compatibility of the hemlock parsley and the Chinese angelica has the effects of promoting blood circulation, removing blood stasis, promoting qi circulation and relieving pain.
In the embodiment of the invention, the ginger is slightly warm in nature, enters lung, spleen and stomach channels, has the effects of relieving exterior syndrome, dispelling cold, warming middle energizer, arresting vomiting, warming lung, relieving cough and detoxifying, and can be used for treating cold due to wind-cold, spleen and stomach cold, stomach cold vomiting, lung cold cough and fish and crab toxin relieving. When the ginger is externally applied, the ginger can permeate into subcutaneous tissues and mucous membranes through the skin surface layer, so as to enter a blood circulation system, play a role in promoting whole body qi and blood circulation, expelling cold, clearing damp, clearing and activating the channels and collaterals, relieve and eliminate body pain, improve body heat energy and improve physique, and has a good effect. It should be noted here that ginger is not only mild in drug property and less in irritation, but also can promote drug action, so that the drug effect is more rapid, and pain of a patient is relieved more rapidly.
In the present example, capsicum is soaked in wine and removed, so that the composition contains capsaicin and an alcohol component. When the externally applied medicine is applied, the capsaicin and the alcohol can promote the vasodilatation of the affected part, further promote the local blood circulation and the medicine application, and have quick effect and better effect. Specifically, the pepper has the effects of warming the middle-jiao to dispel cold, descending qi and promoting digestion, and can be used for treating stomach cold and qi stagnation, abdominal distention and pain, emesis, dysentery, rheumatalgia and chilblain. When the capsicum is externally used as a liniment, the local skin blood vessels after being applied can be dilated in a reflecting way, the local blood circulation is promoted, and the capsicum also has certain antibacterial and anti-inflammatory effects. The main component capsaicin in the capsicum has good effect on treating arthritis, muscle pain, low back pain, sports sprain and other symptoms. Moreover, the capsaicin can make the affected part warm and has better use feeling. The wine is brewed from sorghum, rice, barley and the like as raw materials, has warm nature, has the effects of promoting blood circulation and promoting the medicinal potential, and can be used for treating wind-cold arthralgia, spasm and urgency of tendons and vessels, chest obstruction, cardiodynia, abdominal psychroalgia and the like. In addition, in the embodiment of the invention, the alcoholic strength of the wine is 50-56 degrees. On the other hand, if the alcohol content is high, the irritation to the affected part is too strong, and if the alcohol content is low, the amount of capsaicin, which is the main active ingredient in capsicum, dissolved in wine is low (the solubility of capsaicin in 95% alcohol is 8-12%), and the expected effect cannot be achieved. Therefore, the capsaicin and the alcohol have certain treatment effects on symptoms such as limb weakness, soreness and weakness of waist and knees, headache, dizziness and the like, can dilate blood vessels of affected parts, promotes effective medicinal ingredients in the composition to quickly play a role, and achieves the treatment effect.
In the embodiment of the invention, the rapeseed oil is used as a blending component, and the medicines are blended to prepare the ointment, so that the coating feeling is improved, and the absorption efficiency of skin on the traditional Chinese medicine components of the ointment can be improved, thereby ensuring better treatment effect. Specifically, the rapeseed oil is edible oil squeezed from rapeseed, is warm in nature, and not only has the effects of moistening dryness, killing insects and eliminating swelling and toxin, but also has the effects of activating blood circulation to dissipate blood stasis and softening blood vessels. When the ointment is applied externally, the ointment can not only treat innominate toxic swelling, rubella, skin itch and eczema, but also effectively promote drug penetration, so that the ointment has quick response.
The embodiment of the invention comprises the following raw materials in parts by weight: 20 parts of notopterygium root, 20 parts of rhubarb, 20 parts of clove, 20 parts of asarum, 30 parts of myrrh, 30 parts of angelica, 40 parts of rhizoma cyperi, 50 parts of turmeric, 50 parts of safflower, 100 parts of ligusticum wallichii, 100 parts of pseudo-ginseng, 150 parts of epimedium, 250 parts of rapeseed oil, 500 parts of musk, 500 parts of poria cocos, 6 parts of hot pepper, 60 parts of wine and 5000 parts of ginger. The ointment prepared by the formula has moderate viscosity and strong applicability, has better curative effect on symptoms such as myasthenia of limbs, soreness and weakness of waist and knees, difficulty in walking, dizziness and headache caused by cervical syndrome, has smaller stimulation to skin and has better using effect.
The invention provides a preparation method of a composition for treating cervical syndrome, which comprises the following steps:
and (3) hermetically soaking the peppers in the wine, stirring the wine during the soaking process, and fishing out and removing the peppers after the soaking is finished to obtain the pepper wine. Wherein, the pepper needs to be sealed and soaked in the wine to prevent the phenomenon of alcohol volatilization in the soaking process, thereby reducing the alcohol content and reducing the absorption effect of the skin on the ointment. Moreover, when the alcohol is volatilized due to the unsealing, the dissolving-out amount of capsaicin is reduced during the soaking process, thereby affecting the treatment effect of the ointment. During the soaking process, the capsaicin is gradually dissolved and diffused into the wine by taking the pepper as the center. When the concentration of capsaicin in the wine surrounding the peppers is relatively high, the dissolving rate and the dissolving amount of the capsaicin are reduced, the wine is properly stirred at the moment, the capsaicin can be rapidly diffused into the wine, the dissolving rate and the dissolving amount of the capsaicin are effectively improved, and the treatment effect of the ointment is ensured. However, if the number of times of stirring is too large, excessive volatilization of alcohol will occur during the stirring process, and the amount of released capsaicin will decrease as the alcohol content decreases; when the stirring times are less, the dissolving rate of the capsaicin is slower, the preparation period of the capsicum wine is increased, and the time cost of the ointment is increased. In the embodiment of the invention, the soaking time is 7-10 days, so that the dissolving-out amount of the capsaicin can reach the expected treatment effect, the preparation period of the ointment is short, and the time cost is low. In other embodiments, the producer can cut and crush the pepper and then soak the pepper, so that the production period of the pepper wine is shortened, and the dissolution rate of capsaicin can be increased.
Pulverizing and grinding the raw materials except Capsici fructus, wine and oleum Rapae to obtain powder with particle size of 80-140 mesh, adding oleum Rapae and Capsici fructus wine, respectively, and mixing to obtain unguent. The particle size of the crushed material is 80-140 meshes, so that the absorption and the osmosis of the skin on the medicine can be enhanced, the ointment can be applied to the skin more easily, and the treatment effect is good; in addition, the medicine with smaller particle size can ensure that the efficacy and the action of the ointment on the affected part are more consistent on the premise of uniform mixing. Moreover, because the particle size is small, the specific surface area is large, and the acting force of the particles among the medicines is strong, the ointment is not easy to disperse, and has good aggregation and adhesion states, so that the ointment can be quickly and uniformly applied to the affected part. Then, rapeseed oil is added into the ointment, the mixture is uniformly mixed with the medicines, and the prepared pepper wine is added, so that the volatilization loss of the pepper wine can be effectively avoided, and the penetration and absorption effects of the ointment are ensured. It should be noted here that when the particle size of the drug is too small, the manufacturing cost of the ointment is high, and the cost performance is reduced, while when the particle size of the drug is large, not only the drug effect cannot achieve the expected effect, but also the tactile sensation is poor, and the comprehensive use effect is not good.
In the embodiment of the invention, the raw material mixed with the rapeseed oil is placed in an ultrasonic device for ultrasonic treatment, so that the components in the medicine can be further broken into walls (cell walls) and dissolved into the rapeseed oil, and the curative effect is improved. In the same way, the ultrasound can promote the release of the effective components in the ointment, so that the ointment can quickly permeate to subcutaneous tissues and mucous membranes and enter a blood circulation system, thereby achieving better treatment effect. It should be noted that, by performing the ultrasonic treatment before adding the capsicum wine, on one hand, the loss of the capsicum wine can be reduced, and on the other hand, the effective components further dissolved out by the ultrasonic treatment can be dissolved in the capsicum wine, and the effective components can be quickly permeated by the wine and the capsaicin, so that the effect taking speed is increased, and the effect is better, for example, the effective components such as gingerol, brass compounds, muscone and the like are effective. In the embodiment of the invention, the ultrasonic frequency and the ultrasonic time are respectively 20-40kHz and 5-15min, so that the treatment effect of the ointment is further improved, and the ultrasonic time is shorter, so that the preparation period of the ointment is shorter. In addition, the ultrasonic treatment can further improve the drug effect of the ointment, has the characteristics of energy conservation and no pollution, and is easy to automate.
The features and properties of the present invention are described in further detail below with reference to examples.
Example 1
The present embodiment aims to provide a composition for treating cervical syndrome, comprising:
the wine comprises 20g of notopterygium root, 20g of rhubarb, 20g of clove, 20g of asarum, 30g of myrrh, 30g of angelica, 40g of rhizoma cyperi, 50g of turmeric, 50g of safflower, 100g of ligusticum wallichii, 100g of pseudo-ginseng, 150g of epimedium, 250g of rapeseed oil, 500g of musk, 500g of poria cocos, 6g of hot pepper, 60g of wine and 5000g of ginger, wherein the alcoholic strength of the wine is 52 degrees.
The composition for treating cervical syndrome provided in this example can be prepared as follows:
soaking Capsici fructus in wine for 7-10 days under sealed condition, removing Capsici fructus to obtain Capsici fructus wine;
pulverizing the raw materials except Capsici fructus, wine and oleum Rapae to particle size of 120 mesh, adding oleum Rapae, mixing, adding Capsici fructus wine, and mixing to obtain unguent.
Example 2
The present embodiment aims to provide a composition for treating cervical syndrome, comprising:
15g of notopterygium root, 15g of rhubarb, 15g of clove, 15g of asarum, 20g of myrrh, 20g of angelica, 25g of rhizoma cyperi, 40g of turmeric, 40g of safflower, 75g of ligusticum wallichii, 75g of pseudo-ginseng, 135g of epimedium herb, 200g of rapeseed oil, 495g of musk, 495g of poria cocos, 5g of pepper, 50g of wine and 4000g of ginger, wherein the alcoholic strength of the wine is 50 degrees.
The composition for treating cervical syndrome provided in this example can be prepared as follows:
soaking Capsici fructus in wine for 7-10 days under sealed condition, removing Capsici fructus to obtain Capsici fructus wine;
pulverizing the raw materials except Capsici fructus, wine and oleum Rapae to particle size of 80 mesh, adding oleum Rapae, mixing, adding Capsici fructus wine, and mixing to obtain unguent.
Example 3
The present embodiment aims to provide a composition for treating cervical syndrome, comprising:
30g of notopterygium root, 30g of rhubarb, 30g of clove, 30g of asarum, 40g of myrrh, 40g of angelica, 45g of rhizoma cyperi, 60g of turmeric, 60g of safflower, 105g of ligusticum wallichii, 110g of pseudo-ginseng, 165g of epimedium, 300g of rapeseed oil, 505g of musk, 505g of poria cocos, 7g of hot pepper, 70g of wine and 6000g of ginger, wherein the alcoholic strength of the wine is 56 degrees.
The composition for treating cervical syndrome provided in this example can be prepared as follows:
soaking Capsici fructus in wine for 7-10 days under sealed condition, removing Capsici fructus to obtain Capsici fructus wine;
pulverizing the raw materials except Capsici fructus, wine and oleum Rapae to particle size of 140 mesh, adding oleum Rapae, mixing, adding Capsici fructus wine, and mixing to obtain unguent.
Example 4
The present embodiment aims to provide a composition for treating cervical syndrome, comprising:
25g of notopterygium root, 25g of rhubarb, 25g of clove, 25g of asarum, 25g of myrrh, 25g of angelica, 30g of rhizoma cyperi, 45g of turmeric, 45g of safflower, 85g of ligusticum wallichii, 85g of pseudo-ginseng, 145g of epimedium, 220g of rapeseed oil, 497g of musk, 497g of poria cocos, 5.5g of hot pepper, 55g of wine and 4500g of ginger, wherein the alcohol content of the wine is 55 degrees.
The composition for treating cervical syndrome provided in this example can be prepared as follows:
soaking Capsici fructus in wine for 7-10 days under sealed condition, removing Capsici fructus to obtain Capsici fructus wine;
pulverizing the raw materials except Capsici fructus, wine and oleum Rapae to particle size of 100 mesh, adding oleum Rapae, mixing, adding Capsici fructus wine, and mixing to obtain unguent.
Example 5
The present embodiment aims to provide a composition for treating cervical syndrome, comprising:
28g of notopterygium root, 28g of rhubarb, 28g of clove, 28g of asarum, 35g of myrrh, 35g of angelica, 35g of rhizoma cyperi, 55g of turmeric, 55g of safflower, 95g of ligusticum wallichii, 95g of pseudo-ginseng, 155g of epimedium herb, 280g of rapeseed oil, 503g of musk, 503g of poria cocos, 6.5g of hot pepper, 65g of wine and 5500g of ginger, wherein the alcohol content of the wine is 55 degrees.
The composition for treating cervical syndrome provided in this example can be prepared as follows:
soaking Capsici fructus in wine for 7-10 days under sealed condition, removing Capsici fructus to obtain Capsici fructus wine;
pulverizing the raw materials except Capsici fructus, wine and oleum Rapae to particle size of 130 mesh, adding oleum Rapae, mixing, adding Capsici fructus wine, and mixing to obtain unguent.
Example 6
The present embodiment aims to provide a composition for treating cervical syndrome, comprising:
20g of notopterygium root, 20g of rhubarb, 20g of clove, 20g of asarum, 30g of myrrh, 30g of angelica, 40g of rhizoma cyperi, 50g of turmeric, 50g of safflower, 100g of ligusticum wallichii, 100g of pseudo-ginseng, 150g of epimedium, 250g of rapeseed oil, 500g of musk, 500g of poria cocos, 6g of hot pepper, 60g of wine and 5000g of ginger.
The composition for treating cervical syndrome provided in this example can be prepared as follows:
soaking Capsici fructus in wine for 7-10 days under sealed condition, removing Capsici fructus to obtain Capsici fructus wine;
pulverizing raw materials except Capsici fructus, wine and oleum Rapae to particle size of 120 mesh, making into pulverized material, adding oleum Rapae, mixing, performing ultrasonic treatment, adding Capsici fructus wine, and mixing to obtain unguent, wherein the ultrasonic frequency and ultrasonic time are 40kHz and 15min respectively.
Example 7
The present embodiment aims to provide a composition for treating cervical syndrome, comprising:
20g of notopterygium root, 20g of rhubarb, 20g of clove, 20g of asarum, 30g of myrrh, 30g of angelica, 40g of rhizoma cyperi, 50g of turmeric, 50g of safflower, 100g of ligusticum wallichii, 100g of pseudo-ginseng, 150g of epimedium, 250g of rapeseed oil, 500g of musk, 500g of poria cocos, 6g of hot pepper, 60g of wine and 5000g of ginger.
The composition for treating cervical syndrome provided in this example can be prepared as follows:
soaking Capsici fructus in wine for 7-10 days under sealed condition, removing Capsici fructus to obtain Capsici fructus wine;
pulverizing raw materials except Capsici fructus, wine and oleum Rapae to particle size of 120 mesh, making into pulverized material, adding oleum Rapae, mixing, performing ultrasonic treatment, adding Capsici fructus wine, and mixing to obtain unguent, wherein the ultrasonic frequency and ultrasonic time are 20kHz and 5min respectively.
Effect example 1
After years of treatment and accumulation, the effective rate of the ointment for patients reaches 93 percent, and the specific use effect is as follows:
patient one, female, 55 years old, with clinical symptoms prior to use: dizziness, dim eyesight, tinnitus, soreness and weakness of shoulders, sciatica caused by lumbar disc protrusion, leg numbness and leg weakness, and the walking can not be performed normally; after the ointment prepared in the embodiment 1 is used, the pain is obviously relieved, the symptoms of dizziness, dim eyesight and tinnitus disappear after one week, the symptoms of shoulder weakness and leg numbness and leg weakness are relieved, and the user can walk normally after 3 months; the curative effect is judged to be significant.
Patient two, male, 65 years old, with the clinical symptoms before use: meniscus injury, bony spur in the knee, rheumatism in the knee, difficulty in walking, and limited movement; after the ointment prepared in example 1 is used, pain is relieved, the walking can be performed slowly after one week, the pain is slight, and the walking is performed freely after 3 months; the curative effect is judged to be significant.
Patient three, female, age 53, with pre-use clinical symptoms: dizziness, tinnitus, dim eyesight, soreness and weakness of shoulders, sciatica caused by lumbar disc protrusion, leg numbness and leg weakness, incapability of walking normally and obviously limited activity; after the ointment prepared in the example 1 is used, the pain is obviously relieved, the symptoms of dizziness, dim eyesight and tinnitus disappear after one week, the symptoms of shoulder weakness and leg numbness and leg weakness are relieved, and the patient walks normally after 3 months; the curative effect is judged to be significant.
Effect example 2
The ointments prepared in examples 1 to 7 are numbered as 1 to 7, and after collection and screening, 72 volunteers with cervical syndrome are selected, wherein the symptoms comprise 16 volunteers with limp and weak upper limbs, 16 volunteers with limp and weak lower limbs, 21 volunteers with limp and weak limbs, 7 patients with limited walking and 23 patients with dizziness and headache, and the effects of grouping and using the ointments No. 1 to 7 in the following manner are shown in Table 1.
The product prepared in example 1 was used as a plaster: 3 upper limbs are weak, 3 lower limbs are weak, 3 limbs are weak, walking is limited by 1, and 4 dizziness and headache are caused;
the product prepared in example 2 was used as a plaster: 2 weak and limp upper limbs, 2 weak and limp lower limbs, 3 weak and limp limbs, 1 walking limitation and 3 dizziness and headache;
the product prepared in example 3 was used as a plaster: 2 weak and limp upper limbs, 2 weak and limp lower limbs, 3 weak and limp limbs, 1 walking limitation and 3 dizziness and headache;
the product prepared in example 4 was used as a plaster: 2 weak and limp upper limbs, 2 weak and limp lower limbs, 3 weak and limp limbs, 1 walking limitation and 3 dizziness and headache;
the product prepared in example 5 was used as a plaster: 2 weak and limp upper limbs, 2 weak and limp lower limbs, 3 weak and limp limbs, 1 walking limitation and 3 dizziness and headache;
the product prepared in example 6 was used as a plaster: 3 upper limbs are weak, 3 lower limbs are weak, 3 limbs are weak, walking is limited by 1, and 4 dizziness and headache are caused;
the product prepared in example 7 was used as a plaster: 2 weak and limp upper limbs, 2 weak and limp lower limbs, 3 weak and limp limbs, 1 limited walking and 3 dizziness and headache.
It is noted here that of the 7 volunteers, 38 male and 34 female; age 45-66 years; the course of the disease is 4-40 months. Moreover, during the symptomatology, patients with the same symptoms were selected with less variation in severity.
TABLE 1 Effect after application of ointment
Figure BDA0003001988430000151
As can be seen from the effect examples 1 and 2, the ointment prepared in the examples 1 to 7 can effectively relieve pain, takes effect quickly, and has good treatment effect on symptoms such as soreness and weakness of limbs, difficulty in walking, dizziness and headache and the like caused by cervical syndrome. Moreover, the ointment also has certain curative effect on patients suffering from rheumatic pain. In addition, the ointment has certain functions of diminishing inflammation and reducing swelling, and is suitable for external application and pain relief. It should be noted here that the ointments prepared in examples 3, 6 and 7 are more effective and shorter in treatment period for patients with the same symptoms and less difference.
In conclusion, the composition for treating cervical syndrome provided by the embodiment of the invention has a good curative effect on symptoms such as pain, limb weakness, difficulty in walking, dizziness and nausea and the like caused by cervical syndrome. Specifically, the composition can rapidly permeate to subcutaneous tissues and mucous membranes and enter a blood circulation system, so that better relieving and treating effects are achieved. The composition contains epimedium and musk, so that the composition has a good effect of treating symptoms such as limb weakness, walking difficulty, weakness of waist and knees and the like, and is supplemented with notopterygium root, asarum, myrrh, angelica, turmeric and safflower, so that the composition can further relieve symptoms such as limb weakness, weakness of waist and knees, walking difficulty and the like, and also has a certain relieving effect on headache and dizziness. The compatibility of the ligusticum wallichii and the rhizoma cyperi in the composition can effectively treat headache, and the composition can effectively treat symptoms such as dizziness, vomiting, headache and the like caused by cervical syndrome because the composition contains the clove, the rheum officinale and the poria cocos. Moreover, the ginger not only has the function of promoting qi and blood circulation, but also has the effects of expelling cold, clearing damp, clearing and activating the channels and collaterals, and can promote the composition to quickly exert the effect, quickly take effect and relieve the pain of patients. In addition, the preparation method of the composition is simple and easy to implement, the preparation period is short, and the automation is easy to realize.
The embodiments described above are some, but not all embodiments of the invention. The detailed description of the embodiments of the present invention is not intended to limit the scope of the invention as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Claims (10)

1. The composition for treating cervical syndrome is characterized by comprising the following raw materials in parts by weight: 15-30 parts of notopterygium root, 15-30 parts of rhubarb, 15-30 parts of clove, 15-30 parts of asarum, 20-40 parts of myrrh, 20-40 parts of angelica, 25-45 parts of rhizoma cyperi, 40-60 parts of turmeric, 40-60 parts of safflower, 75-105 parts of ligusticum wallichii, 75-110 parts of pseudo-ginseng, 135-165 parts of epimedium, 495-505 parts of musk, 495-505 parts of poria cocos and 4000-6000 parts of ginger.
2. The composition for treating cervical syndrome according to claim 1, further comprising 5-7 parts by weight of capsicum and 50-70 parts by weight of wine.
3. The composition for treating cervical syndrome according to claim 2, further comprising 200-300 parts by weight of rapeseed oil.
4. The composition for treating cervical syndrome according to claim 3, wherein the alcohol content of the wine is 50-56 degrees.
5. The composition for treating cervical syndrome according to claim 3 or 4, characterized by comprising the following raw materials in parts by weight: 20 parts of notopterygium root, 20 parts of rhubarb, 20 parts of clove, 20 parts of asarum, 30 parts of myrrh, 30 parts of angelica, 40 parts of rhizoma cyperi, 50 parts of turmeric, 50 parts of safflower, 100 parts of ligusticum wallichii, 100 parts of pseudo-ginseng, 150 parts of epimedium, 250 parts of rapeseed oil, 500 parts of musk, 500 parts of poria cocos, 6 parts of hot pepper, 60 parts of wine and 5000 parts of ginger.
6. A method for preparing a composition for treating cervical syndrome according to any one of claims 3 to 5, comprising the steps of:
soaking the hot pepper in the wine, and removing the hot pepper to obtain hot pepper wine;
pulverizing the raw materials except the Capsici fructus, wine and oleum Rapae to obtain pulverized material, adding Capsici fructus wine and oleum Rapae, mixing, and making into unguent.
7. The method for preparing a composition for the treatment of cervical syndrome according to claim 6, wherein the soaking time is 7-10 days.
8. The method for preparing a composition for the treatment of cervical syndrome according to claim 7, wherein the pulverized material has a particle size of 80-140 mesh.
9. The method for preparing a composition for the treatment of cervical syndrome according to claim 8, wherein the capsicum wine is added and mixed after the pulverized material is mixed with the rapeseed oil.
10. The method for preparing a composition for the treatment of cervical syndrome according to claim 9, wherein the raw materials except the capsicum wine are subjected to ultrasound after the rapeseed oil is added and before the capsicum wine is added, the ultrasound frequency is 20-40kHz, and the ultrasound time is 5-15 min.
CN202110350474.9A 2021-03-31 2021-03-31 Composition for treating cervical syndrome and preparation method thereof Pending CN113018410A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN202036382U (en) * 2011-04-17 2011-11-16 何任 Collar for treating cervical spondylosis
CN107625926A (en) * 2016-07-18 2018-01-26 威海贯标信息科技有限公司 A kind of friendly pillow of cervical vertebra

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN202036382U (en) * 2011-04-17 2011-11-16 何任 Collar for treating cervical spondylosis
CN107625926A (en) * 2016-07-18 2018-01-26 威海贯标信息科技有限公司 A kind of friendly pillow of cervical vertebra

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