CN113018337A

CN113018337A - Compound prescription for treating eye diseases and preparation method and application thereof

Info

Publication number: CN113018337A
Application number: CN202110024838.4A
Authority: CN
Inventors: 谢刚; 蔡天龙
Original assignee: Shenzhen Good Health Biological Pharmaceutical Co ltd
Current assignee: Shenzhen Good Health Biological Pharmaceutical Co ltd
Priority date: 2021-01-08
Filing date: 2021-01-08
Publication date: 2021-06-25

Abstract

The invention is a medical compound technical field, has provided a compound for the treatment of eye disease and its preparation method and application, this formulation includes 5 Chinese herbal medicines of folium Artemisiae Argyi, frankincense, Myrrha, radix Paeoniae alba, radix Glycyrrhizae Preparata, it has effects of clearing away heat and toxic materials, detumescence and relieving pain, controlling and preventing infection effectively, relieving ciliary muscle, accelerate wound healing, curative effect is rapid, cheap. Solves the problem that the patients suffering from the eye diseases can not eradicate the pains of various eye diseases.

Description

Compound prescription for treating eye diseases and preparation method and application thereof

Technical Field

The invention belongs to the technical field of pharmaceutical compound, and provides a compound for treating eye diseases, a preparation method and application thereof.

Background

Myopia is one of the common clinical diseases, and causes patients to be unable to see things clearly, to be unable to work or study in daily life, and to be impatient in words. At present, western medicine has a plurality of medicines and methods which have certain effects on treating myopia, astigmatism and presbyopia of eyes, but the western medicine has insufficient parts.

The western medicine method for treating myopia usually adopts operation and excimer laser in-situ keratomileusis, the sequelae after the operation can not be avoided, the treatment course is long, the healing is slow, the cost is high, and the sequelae have recurrence in the latent period after the healing.

The traditional Chinese medicine adopts traditional Chinese medicine for treatment, has certain effects of preventing various eye diseases and correcting eyesight in application, but has the defect of long wound healing time.

The first symptoms of myopia, astigmatism and presbyopia are that the eyes are blurred, and the thing seen when the eyes are opened is shaking and shaking unstable, has no fixed target distance, is divided into the size and distance of the unclear distance, and cannot endure the eye swelling for a long time. Various diseases of eyes become an urgent problem to be solved in life, work and study of people at present. And the health problems of normal life, work, study and physical and mental health of people are seriously influenced due to the low-age trend.

The myopia of eyes is caused by the fact that ciliary muscles of crystalline lenses of the eyeballs are damaged, focal lengths are lengthened and cannot be automatically recovered, the focal lengths are changed, the focal lengths must be shortened to see things clearly, and the simple light and medium myopia is caused by the combined action of genes, environments, personal habits and the like; the function of genetic factors is more obvious when the myopia is high, especially when the myopia is pathological. Environmental factors that contribute to myopia include: this is the reason for long-term near work, less outdoor activities, and especially for excessive use of electronics. This is the principle of wearing spectacles for myopia.

Early inflammation such as astigmatism, presbyopia, conjunctivitis, glaucoma, cataract, etc. is caused by the phenomena of unsmooth eyeball vascular occlusion, low permeability, microcirculation thrombosis, internal coagulation, stasis in the middle and congestion outside. The greatest risk of the eye having bloody streaks, redness and swelling, i.e., inflammation of the conjunctiva, is infection. Because of wound surface microvascular embolism, antibiotics can not reach wound surface parts clinically through blood circulation delivery, and immune substances such as eye free antibodies, free cells and the like can not be supplied to the wound surface in time, the congestion and anti-infection effects of eyes are not ideal. Therefore, the treatment effect of the ocular inflammation is to completely heal the wound of the patient, recover the normal function of the eye to the maximum extent, recover the optic nervous system of the eye, the retinal systems and the function, myopic retinopathy and the like, and recover the normal vision of the eye to the greatest extent.

Disclosure of Invention

In view of the problems in the prior art, the invention provides a compound for treating eye diseases and a preparation method and application thereof. The invention is realized by the following technical scheme:

a Chinese medicine for treating ophthalmopathy is prepared from 5 Chinese-medicinal materials including argyi leaf, frankincense, myrrh, white peony root, liquorice root, etc.

The medicinal material compositions are obtained by a great amount of exploration of the inventor, if more than one of the medicinal material compositions is lacked, the effect is reduced, and the treatment effect on the eye diseases is reduced or no effect is achieved. The eye disease sufferers can not see clearly the objects, and the work and the life are seriously damaged and influenced.

It has the functions of clearing away heat and toxic material, eliminating swelling, relieving pain, preventing infection, relieving ciliary muscle, promoting wound healing, fast curative effect and low cost. Solves the problem that the patients suffering from the eye diseases can not eradicate the pains of various eye diseases. Specifically, the method comprises the following steps:

folium artemisiae argyi: borneol and dry leaves. Pungent, bitter, warm, with little toxicity, enter liver, spleen and kidney meridians, with the following effects: warming channels to stop bleeding, eliminating dampness to relieve itching, dispelling cold. The main treatment symptoms are as follows: hemorrhage, and can inhibit ocular vascular hemorrhage.

Frankincense: pungent, bitter and slightly warm in taste; the functional indications are as follows: promoting blood circulation, activating qi-flowing, dredging channels, relieving pain, relieving swelling, promoting granulation, eliminating ocular edema, activating ocular tissue cells, and promoting metabolism.

Myrrh: bitter and flat; the functional indications are as follows: promoting blood circulation to relieve pain, eliminating swelling and promoting granulation, traumatic injury, carbuncle, swelling, sore and ulcer, conjunctival congestion and swelling. Relieving pain and swelling due to eye trauma.

Licorice root: sweet, dry and enter heart, lung, spleen and stomach meridians. The efficacy is as follows: tonify heart and spleen qi, dispel phlegm and relieve cough, relieve spasm and pain, remove toxicity, and harmonize property of the medicine. The main treatment symptoms are as follows: the eye drop has the effects of treating deficiency of heart-qi, swelling and pain of eyes, treating fever, vexation, insomnia, and helping middle-aged and elderly people with eye diseases to quickly fall asleep.

White peony root: sweet, sour, bitter and slightly cold, entering liver, spleen and heart meridians. The efficacy is as follows: nourish blood and astringe yin, soften liver to alleviate pain, and inhibit liver yang. The main treatment symptoms are as follows: blood deficiency syndrome and liver yang hyperactivity syndrome, and is beneficial for protecting eyes and improving eyesight.

As a preferred technical scheme of the invention, according to the weight portion ratio, the folium artemisiae argyi 15-25 parts, the frankincense 8-12 parts, the myrrh 6-10 parts, the white peony root 6-12 parts and the roasted liquorice 3-7 parts

As a preferred technical scheme of the invention, the optimal weight parts of the Chinese medicinal herbs in the formula are 20 parts of folium artemisiae argyi, 10 parts of frankincense, 10 parts of myrrh, 10 parts of radix paeoniae alba and 5 parts of honey-fried licorice root.

As a preferred technical scheme of the invention, the traditional Chinese medicines are weighed according to a certain weight proportion, a proper amount of water is added, and the supernatant is extracted by high-temperature and high-pressure extraction.

As a preferred technical scheme of the invention, the high-temperature and high-pressure extraction comprises that the shell side of the used medicinal materials and a pressure container (extraction tank) are designed to be at 120 ℃ at high temperature, and a jacket is 143 ℃; the high-pressure maximum allowable working pressure is: the shell pass is carried out at normal pressure, and the mixture is cooked at high temperature and high pressure of 0.30Mpa in a jacket for 6 hours for extraction.

Compared with the prior art, the invention has the advantages that:

the invention aims to provide a compound eye care solution for protecting eyes, which is used for treating chronic asthenopia, dry eye disease, eyeground pathological changes caused by chronic diseases, juvenile myopia, early cataract of old people and other symptoms of deficiency of qi and blood, malnutrition of veins of eyes, blood stasis and dampness and cold. Acute conjunctivitis, hyperemic conjunctivitis, hemorrhagic ophthalmopathy, and glaucoma. It has the functions of clearing away heat and toxic material, eliminating swelling, relieving pain, preventing infection, relieving ciliary muscle and promoting wound healing, and has fast curative effect and low cost. Solves the problem that the patients suffering from eye diseases can not eradicate the pain of various eye diseases for a long time.

Detailed Description

The invention is further disclosed in the following examples. It should be understood that these examples are for illustrative purposes only and are not intended to limit the scope of the present invention.

Example 1

Taking 15 parts (kg) of folium artemisiae argyi, 12 parts of frankincense, 10 parts of myrrh, 10 parts of radix paeoniae alba and 5 parts of radix glycyrrhizae preparata. Adding 10 times of water, extracting at high temperature and under high pressure, respectively separating different Chinese medicinal materials, and collecting supernatant.

The shell pass temperature of the medicinal materials and the pressure vessel is 120 deg.C, and the jacket temperature is 143 deg.C. The high-pressure maximum allowable working pressure is: the shell pass is at normal pressure, and the extraction is carried out by boiling for 6 hours at high temperature and high pressure in a large 1500L extraction tank with a jacket of 0.30 Mpa.

Example 2

Taking 20 parts (kg) of folium artemisiae argyi, 10 parts of frankincense, 12 parts of myrrh, 10 parts of radix paeoniae alba and 8 parts of radix glycyrrhizae preparata. Adding 10 times of water, extracting at high temperature and under high pressure, respectively separating different Chinese medicinal materials, and collecting supernatant.

Example 3

Dripping appropriate amount of the extract of example 1 on the surface of the eye wound, soaking with gauze, and directly applying on the surface of the eye, or taking the example

Somebody, woman, 13 years old, Shenzhen, Shentian, Shenzhong, is in Shazhong school. The front vision is adjusted by the left eye: 0.6 degrees, right eye: 0.6 degree. The children wear the myopia glasses with high degrees, and the children can not see characters on the blackboard clearly every day when speaking that the eyes of the children sitting on the back row are difficult to see, and the teacher is called to adjust the seat. After the medicine of the invention is used for 3 months, the left eye with the back vision is adjusted to be: 1.2 degrees, right eye: 1.2 degrees. Is clear and easy to see. The effect is better when the user sleeps at night. The severe patients take the medicine three times a day, and after 3 months, pseudomyopia patients with about 200 degrees generally become normal vision.

Example 4

The proper amount of the extract liquid in the example 2 is dripped on the wound surface of the eye and soaked by gauze and directly applied to the surface of the eye, or the proper amount of the extract liquid in the example 1 is prepared and applied to the surface of the eye 2-3 times a day.

A certain woman, 58 years old, Dangshan county, Dali building village. Itching, blurring, presbyopia, tearing and myopia of the eye. People feel that eyes are frequently tired, dry and have poor rest at night. The medicine is dropped on the wound surface of eyes, and a person is soaked by gauze and directly applied on the surface of the eyes, so that the medicine disclosed by the invention can diminish inflammation, and the symptoms are basically cured after more than 60 days.

Example 5

Somebody, woman, 68 years old, Shenzhen, Shentian Shacun. The eyes are blurred, prick with pain as soon as they are open, and tear is constantly flowing through the eyes. The lens of the eyeball has white apt matter and belongs to the early cataract patients. The medicine is dropped on the wound surface of eyes, is soaked by gauze and is directly applied on the surface of the eyes, and the medicine of the invention can diminish inflammation, and the symptoms can be basically cured after more than 90 days. White easy substances in the lens of the eyeball are gradually faded and stasis is removed. Vision is substantially restored.

The above embodiments are preferred embodiments of the present invention, but the present invention is not limited thereto. Furthermore, it will be appreciated that various alterations and modifications may be made by those skilled in the art after reading the above teachings of the invention, and such equivalents are intended to fall within the scope of the invention as defined in the claims appended hereto.

Claims

1. A Chinese medicine for treating ophthalmopathy is prepared from 5 Chinese-medicinal materials including argyi leaf, frankincense, myrrh, white peony root, liquorice root, etc.

2. The compound prescription for treating eye diseases according to claim 1, characterized in that, according to the weight portion ratio, the Chinese mugwort leaves 15-25 parts, the frankincense 8-12 parts, the myrrh 6-10 parts, the white peony root 6-12 parts and the roasted liquorice 3-7 parts.

3. The compound prescription for treating eye diseases according to claim 1, characterized in that, according to the weight portion ratio, the Chinese mugwort leaves 20 portions, the frankincense 10 portions, the myrrh 10 portions, the white peony root 10 portions and the honey-fried licorice root 5 portions.

4. The compound prescription for treating eye diseases according to claim 1, characterized in that, the traditional Chinese medicine is weighed according to the weight proportion, a proper amount of water is added, and the supernatant is extracted by high temperature and high pressure extraction, thus obtaining the compound prescription.

5. The formulation as set forth in claim 4, wherein said high temperature, high pressure extraction comprises: the high temperature design temperature of the medicinal materials and the pressure vessel is 120 ℃ in the shell pass and 143 ℃ in the jacket; the high-pressure maximum allowable working pressure is: the shell pass is carried out at normal pressure, and the mixture is cooked at high temperature and high pressure of 0.30Mpa in a jacket for 6 hours for extraction.

6. A method for preparing the compound preparation for treating eye diseases according to any one of claims 1 to 5, which is characterized in that the traditional Chinese medicines are weighed according to the weight proportion, a proper amount of water is added, and the supernatant is extracted by high-temperature and high-pressure extraction to obtain the compound preparation.

7. The method of claim 6, wherein the high temperature, high pressure extraction comprises: the high temperature design temperature of the medicinal materials and the pressure vessel is 120 ℃ in the shell pass and 143 ℃ in the jacket; the high-pressure maximum allowable working pressure is: the shell pass is carried out at normal pressure, and the mixture is cooked at high temperature and high pressure of 0.30Mpa in a jacket for 6 hours for extraction.