CN112998020A

CN112998020A - Insecticidal composition containing second-generation ryanodine receptor inhibitor and application thereof

Info

Publication number: CN112998020A
Application number: CN201911341492.XA
Authority: CN
Inventors: 姚志牛; 潘利东
Original assignee: Jiangsu Work Is At Bio Tech Ltd
Current assignee: Jiangsu Work Is At Bio Tech Ltd
Priority date: 2019-12-20
Filing date: 2019-12-20
Publication date: 2021-06-22

Abstract

The invention relates to an insecticidal composition containing a second-generation ryanodine receptor inhibitor compound and application thereof, wherein the composition comprises an active component A and an active component B, the active component A is selected from cyantraniliprole, the active component B is selected from one of fenoxycarb and methoprene, and the weight ratio of the two is 80: 1-1: 80. The two active components in the composition have large difference in action mechanism, have obvious synergistic effect on pests such as forestry pests, locust, red imported fire ants, wigglers and the like after being compounded, and have high production and application values.

Description

Insecticidal composition containing second-generation ryanodine receptor inhibitor and application thereof

Technical Field

The invention relates to an insecticidal composition, in particular to an insecticidal composition containing a second generation ryanodine receptor inhibitor and application thereof, in particular to a composition for preventing and controlling biting/sucking insects and chewing insects.

Technical Field

Cyantraniliprole (Cas: 36994-63-1), belonging to the second generation ryanodine receptor inhibitor insecticide, acts on nerve/muscle. The ryanodine receptor is the most main calcium ion release channel, and can generate high affinity with ryanodine, and the ryanodine receptor is acted on to control the calcium ion release channel, so that polypide shrinkage is caused, and death is caused. The insecticidal composition is widely used for preventing various pests such as lepidoptera, coleoptera, diptera and the like, for example: noctuidae, snout moth, plutella, potato leaf beetle, weevil, leaf miner, particularly for fruit trees, vegetables, tea, corn, rice and cotton, and is safe for mammals.

Fenoxycarb (Fenoxycarb, Cas: 72490-01-8), Methoprene (Cas: 40596-69-8) and (S) -Methoprene (S-Methoprene, Cas:65733-16-6), which have the functions of insect growth regulators and broad-spectrum insecticidal effect; but its insecticidal action is non-nervous, and it is characterized by that it possesses strong juvenile hormone activity for several insects, and can result in the processes of killing ovum, inhibiting metamorphosis of adult stage and molting of larval stage, and can result in death of larval later stage or pupal stage, and its effective period is long. The active compound has low toxicity, and can be applied to the non-agricultural fields of sanitation, forestry and the like for preventing and treating pests. The prior art does not disclose the combination of a deltamethrin amide compound with these insecticides and the applicants have surprisingly found that excellent synergistic effects are obtained when these two classes of insecticidal active ingredients are combined.

Disclosure of Invention

The invention provides an efficient and environment-friendly insecticidal composition for preventing and controlling biting/sucking insects and chewing insects.

The invention also aims to provide a preparation formula and application of the composition.

The above object of the present invention is achieved by the following technical solutions:

an insecticidal composition characterized by: the composition comprises an active component A and an active component B, wherein the active component A is selected from cyantraniliprole, the active component B is selected from one of fenoxycarb, methoprene and (S) -methoprene, and the weight ratio of the fenoxycarb to the methoprene is 80: 1-1: 80.

Preferably, the weight ratio of the two is 20: 1-1: 20; further preferably 10:1 to 1: 10; still more preferably 5:1 to 1: 5.

Preferably, the active ingredient B is selected from one of fenoxycarb, (S) -methoprene; even more preferred is (S) -methoprene.

The invention further provides an insecticide preparation, which is characterized by comprising the insecticide composition and a suitable auxiliary agent, wherein the insecticide composition accounts for 0.01-90 wt% of the preparation. Preferably 0.1 to 80 wt%.

The insecticidal composition is prepared into various formulations according to a conventional method, including but not limited to suspending agents, missible oil, aqueous emulsion, micro-emulsion, oil suspending agents, microcapsule suspension-suspending agents, soluble solutions, wettable powder, water dispersible granules, baits, powder, aerosols and spraying agents. The appropriate dosage form is selected according to actual conditions.

The auxiliary components can be wetting agent, dispersant, emulsifier, disintegrant, antifreezing agent, attractant, preservative, defoaming agent, thickening agent, acid-base regulator, binder, solvent, granule carrier, bait, filler, etc.

The wetting agent includes but is not limited to one or more of fatty alcohol polyoxyethylene ether, alkylphenol polyoxyethylene ether, alkyl sulfate, naphthalene sulfonate, alkyl succinate sulfonate and alkylphenol polyoxyethylene ether formaldehyde condensate sulfonate;

the dispersant includes but IS not limited to one or more of polyether phosphate and its salt, alkylphenol polyoxyethylene ether formaldehyde condensate sulfonate, polycarboxylate, block polyether, phenethylphenol polyoxyethylene ether phosphate triethanolamine salt, naphthalene sulfonate formaldehyde condensate, lignin sulfonate, nekal, NNO, MF and IS dispersing;

the emulsifier includes but is not limited to one or more of polyether phosphate, T-60, calcium dodecylbenzene sulfonate, ethylene oxide propylene oxide block copolymer, fatty alcohol polyoxyethylene ether, castor oil polyoxyethylene ether, alkylphenol polyoxyethylene ether, calcium alkyl benzene sulfonate and block polyether;

the disintegrant includes, but is not limited to, one or more of ammonium sulfate, sodium sulfate, glucose, corn starch, ammonium chloride, bentonite, urea, and sodium bicarbonate;

the antifreeze agent comprises but is not limited to one or more of ethylene glycol, propylene glycol, glycerol, sodium chloride, urea, cellosolve, sorbitol, polyvinylpyrrolidone and calcium chloride;

the attractant comprises but is not limited to animal and vegetable oil, lard, soybean oil, peanut oil, rapeseed oil, sesame oil, corn oil, cottonseed oil and wheat germ oil; sugar, glucose, sucrose, fructose, brown sugar, and Mel.

The preservative includes but is not limited to one or more of sodium benzoate, potassium sorbate, sodium dehydroacetate, sodium diacetate, cason, paraben or their sodium salts, bronopol, pentanediol and sodium salicylate;

the defoaming agent comprises but is not limited to one or more of organic silicon compounds, lower alcohols, silicone oil, phosphate esters and fatty acids and fatty acid esters;

the thickening agent includes, but is not limited to, one or more of xanthan gum, fumed SiO2, bentonite, aluminum stearate, xanthan gum powder, polyvinyl alcohol, modified cellulose, magnesium aluminum silicate, gum arabic, gum, gelatin, guar gum, alginic acid, agar, and tall oil;

the pH modifier includes, but is not limited to, one or more of citric acid, oxalic acid, ammonium chloride, tartaric acid and succinic acid;

the solvent comprises but is not limited to one or more of C6-C30 isoparaffin or dearomatization solvent oil, methyl laurate, diethyl maleate, tributyl phosphate and other low-toxicity tasteless monoesters, diester or triester solvents, diisooctyl phthalate, trans-2-hexenol, diesel oil, diisopropyl diacid, dimethyl phthalate, vegetable oil, engine oil and dimethyl sulfoxide;

the granule carrier comprises but is not limited to one or more of attapulgite particles, volcanic rock particles, red brick particles, coal gangue particles, medical stone particles, zeolite particles, corncob particles and walnut shell particles with better adsorption performance;

the bait comprises but is not limited to one or more of wheat flour, soybean flour, corn flour, potato flour, biscuit flour, grain flour and peanut flour;

the filler includes but is not limited to one or more of kaolin, white carbon black, china clay, bentonite, attapulgite, diatomite, white carbon black and light calcium carbonate;

the preparation prepared from the composition is used directly or after being diluted by a solvent, and the application method is selected according to the properties of the composition according to the purpose to be achieved and the environment, and the pests or the habitats thereof are treated by spraying, ultralow volume, retention spraying, hot smog, spraying, powder spraying, broadcasting, feeding, watering and the like.

The insecticidal compositions according to the present invention are suitable for controlling arthropods, more preferably biting and sucking insects, chewing insects and forestry pests.

The biting and sucking insects include, but are not limited to, mosquitoes (e.g., aedes aegypti, aedes albopictus, aedes assailing, culex fatigues, culex pallens, culex haranthis, culex pipiens, culex murraya, anopheles gambiae, anopheles arabica, anopheles nigra, anopheles minutus, anopheles macrolepsis, anopheles schoenopsis sinensis, anopheles hygrophila, etc.).

Preferably, the biting and sucking insects are: culex pipiens pallens, aedes albopictus, anopheles sinensis.

Such chewing insects include, but are not limited to, ants (solenopsis invicta, solenopsis macrocephala, worker ants, solenopsis xifraga, solenopsis invicta, etc.); locusts (locusts mackerel, locusts migratoria in east asia, locusts conoideus, locusts congolensis, locusts migratoria in asia, locusts migratoria in tibet, etc.); termites; forestry pests (lepidoptera larvae), fall moths, pine caterpillars (e.g., pine caterpillar, larch caterpillar, masson pine caterpillar, etc.), poisonous moths (e.g., gypsy moth, willow moth, etc.), boat moths (e.g., poplars canna, poplarch boat moth, etc.), chi moths (e.g., wood inchworm, large bridgeworm, pear chi moth, etc.); moth larvae (such as tobacco meal moth, Indian corn borer, bagel corn moth, and felty moth).

Preferably, the chewing insects are: red imported fire ant, locust and fall webworm.

Compared with the prior art, the invention has the beneficial effects that:

(1) the insect growth regulator is compounded with the insecticide acting on nerve/muscle/breath, has complementary advantages, can effectively control the insect state of each stage of the whole life cycle of pests, reduces the using amount of the insecticide and delays the drug resistance.

(2) The active components of the invention have large difference of action mechanism, and have obvious synergistic effect on pests such as mosquitoes, fall webworms, locusts, red imported fire ants and the like after being compounded.

(3) The insecticidal composition of the invention has low toxicity, high efficiency and environmental protection, and is suitable for preventing and treating pests in the non-agricultural fields of sanitation, forestry, grassland and the like.

Detailed Description

The present invention is further illustrated by the following examples, which are not intended to limit the invention to these embodiments. It will be recognized by those skilled in the art that the present invention encompasses all alternatives, modifications, and equivalents as may be included within the scope of the claims.

Bait example 1: cyantraniliprole bait (0.1%)

The bait agent of the embodiment takes the methoprene as an active ingredient, the soybean meal as bait, a mixture (mixing ratio is 1:0.2:2) of honey, peanut oil and cane sugar as an attractant for the solenopsis invicta, and the potassium sorbate as a preservative, wherein the active ingredients comprise, by weight, cyantraniliprole 0.1%, the bait soybean meal 64.4%, the attractant mixture 35% and the preservative potassium sorbate 0.5%.

Bait example 2: cyantraniliprole bromide

(S) -methoprene bait (total content 0.1%, 20:1)

The bait agent of the embodiment takes cyantraniliprole and fenoxycarb as active ingredients, soybean meal as bait, a mixture (mixing ratio is 1:0.2:2) of honey, peanut oil and cane sugar as an attractant for solenopsis invicta, and potassium sorbate as a preservative, wherein the total content of the cyantraniliprole and the fenoxycarb (20:1) as the active ingredients accounts for 0.1 percent, the soybean meal as the bait accounts for 64.4 percent, the mixture of the attractant accounts for 35 percent, and the potassium sorbate as the preservative accounts for 0.5 percent.

Bait example 3: cyantraniliprole bromide

(S) -methoprene bait (total content 0.1%, 10:1)

The bait agent of the embodiment takes cyantraniliprole and fenoxycarb as active ingredients, soybean meal as bait, a mixture (mixing ratio is 1:0.2:2) of honey, peanut oil and cane sugar as an attractant for solenopsis invicta, and potassium sorbate as a preservative, wherein the total content of the cyantraniliprole and the fenoxycarb (10:1) as the active ingredients accounts for 0.1 percent, the soybean meal as the bait accounts for 64.4 percent, the mixture of the attractant accounts for 35 percent, and the potassium sorbate as the preservative accounts for 0.5 percent.

Bait example 4: cyantraniliprole bromide

(S) -methoprene bait (total content 0.1%, 5:1)

The bait agent of the embodiment takes cyantraniliprole and fenoxycarb as active ingredients, soybean meal as bait, a mixture (mixing ratio is 1:0.2:2) of honey, peanut oil and cane sugar as an attractant for solenopsis invicta, and potassium sorbate as a preservative, wherein the total content of the cyantraniliprole and the fenoxycarb (5:1) as the active ingredients accounts for 0.1 percent, the soybean meal as the bait accounts for 64.4 percent, the mixture of the attractant accounts for 35 percent, and the potassium sorbate as the preservative accounts for 0.5 percent.

Bait example 5: cyantraniliprole bromide

(S) -methoprene bait (total content 0.1%, 1:1)

The bait agent of the embodiment takes cyantraniliprole and fenoxycarb as active ingredients, soybean meal as bait, a mixture (mixing ratio is 1:0.2:2) of honey, peanut oil and cane sugar as an attractant for solenopsis invicta, and potassium sorbate as a preservative, wherein the total content of the cyantraniliprole and the fenoxycarb (1:1) as the active ingredients accounts for 0.1 percent, the soybean meal as the bait accounts for 64.4 percent, the mixture of the attractant accounts for 35 percent, and the potassium sorbate as the preservative accounts for 0.5 percent.

Bait example 6: cyantraniliprole bromide

(S) -methoprene bait (total content 0.1%, 1:5)

The bait agent of the embodiment takes cyantraniliprole and fenoxycarb as active ingredients, soybean meal as bait, a mixture (mixing ratio is 1:0.2:2) of honey, peanut oil and cane sugar as an attractant for solenopsis invicta, and potassium sorbate as a preservative, wherein the total content of the cyantraniliprole and the fenoxycarb (1:5) as the active ingredients accounts for 0.1 percent, the soybean meal as the bait accounts for 64.4 percent, the mixture of the attractant accounts for 35 percent, and the potassium sorbate as the preservative accounts for 0.5 percent.

Bait example 7: cyantraniliprole bromide

(S) -methoprene bait (total content 0.1%, 1:10)

Bait example 8: cyantraniliprole bromide

(S) -methoprene bait (total content 0.1%, 1:20)

Bait example 9: fenoxycarb bait (content 0.1%)

The bait agent of the embodiment takes fenoxycarb as an active ingredient, soybean meal as bait, a mixture (the mixing ratio is 1:0.2:2) of honey, peanut oil and cane sugar as an attractant for solenopsis invicta, and potassium sorbate as a preservative, wherein the active ingredients of fenoxycarb account for 0.1 percent, the bait soybean meal accounts for 64.4 percent, the attractant mixture accounts for 35 percent, and the preservative of potassium sorbate accounts for 0.5 percent by weight.

Bait example 10: cyantraniliprole bromide

Fenoxycarb bait (total content 0.1%, 20:1)

Bait example 11: cyantraniliprole bromide

Fenoxycarb bait (total content 0.1%, 5:1)

Bait example 12: cyantraniliprole bromide

Fenoxycarb bait (total content 0.1%, 1:1)

Bait example 13: cyantraniliprole bromide

Fenoxycarb bait (total content 0.1%, 1:10)

The bait agent of the embodiment takes cyantraniliprole and fenoxycarb as active ingredients, soybean meal as bait, a mixture (mixing ratio is 1:0.2:2) of honey, peanut oil and cane sugar as an attractant for solenopsis invicta, and potassium sorbate as a preservative, wherein the total content of the cyantraniliprole and the fenoxycarb (1:10) as the active ingredients accounts for 0.1 percent, the soybean meal as the bait accounts for 64.4 percent, the mixture of the attractant accounts for 35 percent, and the potassium sorbate as the preservative accounts for 0.5 percent.

Bait example 14: methoprene bait (content 0.1%)

The bait agent of the embodiment takes the methoprene as an active ingredient, the soybean meal as bait, a mixture (mixing ratio is 1:0.2:2) of honey, peanut oil and cane sugar as an attractant for the solenopsis invicta, and the potassium sorbate as a preservative, wherein the active ingredients comprise, by weight, the methoprene 0.1%, the bait soybean meal 64.4%, the attractant mixture 35% and the preservative potassium sorbate 0.5%.

Bait example 15: cyantraniliprole bromide

Methoprene bait (total content 0.1%, 5:1)

The bait agent of the embodiment takes cyantraniliprole and methoprene as active ingredients, soybean meal as bait, a mixture of honey, peanut oil and cane sugar (the mixing ratio is 1:0.2:2) as a solenopsis invicta attractant, and potassium sorbate as a preservative, wherein the total content of the cyantraniliprole and the methoprene (5:1) as the active ingredients accounts for 0.1 percent, the bait soybean meal accounts for 64.4 percent, the attractant mixture accounts for 35 percent, and the potassium sorbate as the preservative accounts for 0.5 percent in percentage by weight.

Bait example 16: cyantraniliprole bromide

Methoprene bait (total content 0.1%, 1:1)

The bait agent of the embodiment takes cyantraniliprole and methoprene as active ingredients, soybean meal as bait, a mixture of honey, peanut oil and cane sugar (the mixing ratio is 1:0.2:2) as a solenopsis invicta attractant, and potassium sorbate as a preservative, wherein the total content of the cyantraniliprole and the methoprene (1:1) as the active ingredients accounts for 0.1 percent, the bait soybean meal accounts for 64.4 percent, the attractant mixture accounts for 35 percent, and the potassium sorbate as the preservative accounts for 0.5 percent in percentage by weight.

Application example 1: laboratory test of culex pipiens pallens larvae

Test subjects: culex pipiens pallens, larvae of 3 years old, indoor sensitive strain.

Test agents: the preparation method comprises the steps of weighing raw materials of cyantraniliprole, fenoxycarb and methoprene respectively, adding a proper amount of acetone for dissolving, adding distilled water for preparing mother liquor with required concentration, and mixing the mother liquor according to a certain proportion to prepare mixed mother liquor.

The test method comprises the following steps: reference pesticide registration sanitary insecticide indoor efficacy test and evaluation part 5: the mosquito larva control agent NY/T1151.5-2014 is prepared by taking white porcelain pots with the diameter of 30cm and the depth of 10cm, putting 4L of clear water in the pots, putting 50 heads of 3-year-old culex pipiens healthy and pale in each pot, adding the prepared agent according to the dosage, observing death and pupation conditions of the larvae every day, and taking out pupae to observe eclosion conditions of the larvae. Three replicates were used and a blank control was set.

And (3) test results: as shown in the table 1, the cyantraniliprole is compounded with fenoxycarb/(S) -methoprene/methoprene, and by utilizing different action mechanisms, the composition has killing effects on culex pipiens pallens larvae and pupae, and the prevention and treatment rate of the compound preparation is higher than that of a single agent under the same dosage.

TABLE 1 Cyantraniliprole complex mixture killing effect on culex pipiens pallens larvae and pupae

Application example 2: in situ solenopsis invicta control test

Test field: shenzhen city south mountain area certain industrial park.

The control object is: and (4) red imported fire ants.

Test agents: bait formulations examples 1-16, blank bait was used as the control formulation.

The test method comprises the following steps: reference pesticide field efficacy test criteria (second) section 149: the pesticide is used for preventing and controlling red imported fire ants GB/T7980.149-2009: there were 20 treatments (bait examples 1-16) with blank bait as a control, 3 replicates, each treatment preceded by a 3-5 meter isolation zone; the ground surface temperature is 20-35 ℃, the medicine is applied when the ground surface is dry, the medicine is annularly spread in a range of 30-100 cm away from an ant nest, the dosage of the preparation is 20 g/nest, and the medicine needs to be applied when raining within 2 days after the medicine is applied; investigating the density of 4 workers before application, 7 days, 30 days and 45 days after application (adopting fresh ham sausage piece trapping method); and (3) calculating the prevention effect of the worker ants, wherein the calculation formula is as follows:

the termite control effect (%) is (1-average termite number after drug trapping/average termite number after drug trapping) x 100.

And (3) test results: in table 2, under the same control dosage, cyantraniliprole and (S) -methoprene/fenoxycarb/methoprene are compounded with the solenopsis invicta bait, and particularly when the compounding ratio is 1: 5-5: 1, compared with a single preparation, the control rate of the compounded preparation is higher than that of the single preparation, and the lasting period is longer than that of the single preparation.

TABLE 2 Cyantraniliprole compound bait for preventing and controlling red imported fire ant on site

Application example 3: laboratory test of fall webworm

Test subjects: fall webworm, 3 instar larva.

Reagent to be tested: the cyantraniliprole, (S) -methoprene, fenoxycarb and methoprene are respectively dissolved by absolute ethyl alcohol, and then the required mother liquor is prepared by using water solution containing 0.1% of Tween 80.

The test method comprises the following steps: preparing the mother liquor into a series of concentrations by adopting an immersion method; soaking fresh poplar leaves which are not polluted by the pesticide in the liquid medicine to be tested for 5s, taking out the poplar leaves, drying the poplar leaves in the shade, wrapping petioles with absorbent cotton, soaking the absorbent cotton in clear water, putting the absorbent cotton into a plastic cup, testing insects for 15 heads in each cup, repeating the steps for 3 times, and establishing clear water contrast; the eggs are placed under the conditions of humidity of 75%, temperature of 24 ℃ and illumination of 14:10(L: D) for feeding, and the number of dead insects and the total number of insects are investigated and recorded after 72 hours.

Performing statistical analysis by POLO statistical analysis software to calculate LC of each medicine₅₀And calculating the co-toxicity coefficient (CTC value) of the mixture according to the Sun Yunpei method.

Measured toxicity index (ATI) ═ standard medicament LC₅₀Test agent LC₅₀)×100。

Theoretical virulence index (TTI) ═ a agent virulence index x percent of a in the mixture + B agent virulence index x percent of B in the mixture.

Co-toxicity coefficient (CTC) × 100 [ measured toxicity index (ATI) of the mixture)/Theoretical Toxicity Index (TTI) of the mixture ].

According to NY/T1154.7-2006 pesticide combination division standard: the co-toxicity coefficient (CTC) is more than or equal to 120 and shows a synergistic effect; the co-toxicity coefficient (CTC) is less than or equal to 80, and the antagonism is shown; 80 < co-toxicity coefficient (CTC) < 120 shows additive effect.

And (3) test results: as shown in Table 3, the composition shows a synergistic effect when the proportion of cyantraniliprole to the (S) -methoprene is 80: 1-1: 80, and the composition has the highest co-toxicity coefficient exceeding 184 when the proportion is 5:1-1: 5; when the proportion of cyantraniliprole to fenoxycarb is 20: 1-1: 20, the co-toxicity coefficient is more than 120, and the synergistic effect is shown, and when the proportion is 5:1-1:5, the co-toxicity coefficient is higher to 171-189; when the ratio of the deltamethrin to the methoprene is 5:1, the highest cotoxicity coefficient can be 169.

TABLE 3 indoor joint toxicity determination of cyantraniliprole compounded mixture for hyphantria cunea

Application example 4: indoor test of locust

Test subjects: locust, 3-year-old nymph.

The test method comprises the following steps: preparing the mother liquor into a series of concentrations by adopting an immersion method; collecting fresh pollution-free alfalfa, soaking in the liquid medicine for 5s, taking out, air drying indoors for later use, putting the same amount of alfalfa treated by the liquid medicine into each feeding basin, picking 15 nymphs of 3-year-old nymphs, repeating for 3 times, and taking clear water as a blank control; the eggs are placed under the conditions of humidity of 75%, temperature of 24 ℃ and illumination of 14:10(L: D) for feeding, and the number of dead insects and the total number of insects are investigated and recorded after 48 hours.

The virulence index (ATI) was measured as (standard agent LC 50/test agent LC50) × 100.

And (3) test results: in Table 4, the composition ratio of cyantraniliprole to (S) -methoprene is 80: 1-1: 80, the synergistic effect is shown, and when the composition ratio is 5:1-1:5, the co-toxicity coefficient is the highest and exceeds 174.

TABLE 4 indoor combined toxicity determination of cyantraniliprole compound mixture to locust

The insecticidal composition containing methoprene and the application thereof have been described by specific examples, and other objects can be achieved by appropriate changes of raw materials and process conditions without departing from the invention, which is obvious for those skilled in the art and is intended to be included within the scope of the invention.

Claims

1. An insecticidal composition characterized by: the composition comprises an active component A and an active component B, wherein the active component A is cyantraniliprole, and the active component B is one selected from fenoxycarb, methoprene and (S) -methoprene in a weight ratio of 80: 1-1: 80.

2. The insecticidal composition of claim 1, wherein: the weight ratio of the two is 20: 1-1: 20.

3. The insecticidal composition of claim 1, wherein: the weight ratio of the two is 5:1-1: 5.

4. Use of the insecticidal composition according to claims 1 to 3 for controlling biting and sucking insects, chewing insects.

5. The use of claim 4, the chewing insect being: red imported fire ant, locust or fall webworm.

6. The use of claim 4, said biting and sucking insects being: mosquitoes and insects.