CN112939560A - Method for 3D printing of pessary - Google Patents

Method for 3D printing of pessary Download PDF

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Publication number
CN112939560A
CN112939560A CN202110351207.3A CN202110351207A CN112939560A CN 112939560 A CN112939560 A CN 112939560A CN 202110351207 A CN202110351207 A CN 202110351207A CN 112939560 A CN112939560 A CN 112939560A
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China
Prior art keywords
pessary
printing
parts
mold
mould
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Pending
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CN202110351207.3A
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Chinese (zh)
Inventor
王丽
牛海英
谢鹏
郭颖
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Individual
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Individual
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Priority to CN202110351207.3A priority Critical patent/CN112939560A/en
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    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B28/00—Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements
    • C04B28/14—Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements containing calcium sulfate cements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/12—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L31/121—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
    • A61L31/124—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix of other specific inorganic materials not covered by A61L31/122 or A61L31/123
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y10/00—Processes of additive manufacturing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y70/00—Materials specially adapted for additive manufacturing
    • B33Y70/10—Composites of different types of material, e.g. mixtures of ceramics and polymers or mixtures of metals and biomaterials
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B2111/00—Mortars, concrete or artificial stone or mixtures to prepare them, characterised by specific function, property or use
    • C04B2111/00034—Physico-chemical characteristics of the mixtures
    • C04B2111/00181—Mixtures specially adapted for three-dimensional printing (3DP), stereo-lithography or prototyping

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Ceramic Engineering (AREA)
  • Inorganic Chemistry (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Composite Materials (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Manufacturing & Machinery (AREA)
  • Structural Engineering (AREA)
  • Civil Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Prostheses (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)

Abstract

The invention discloses a method for 3D printing of a pessary, which belongs to the technical field of medical treatment and comprises the following steps: s1, designing the size; s2, designing a model diagram; s3, printing; s4, injection molding preparation. The invention provides a method for 3D printing of a pessary, which is simple, can print and manufacture a pessary product suitable for a patient, meets the requirements of customization and targeted therapy, has the advantages of high strength, good biocompatibility, temperature resistance, corrosion resistance and the like, greatly prolongs the service life and safety of the pessary, and has great market competitiveness and popularization and application values.

Description

Method for 3D printing of pessary
Technical Field
The invention belongs to the technical field of medical treatment, and particularly relates to a method for 3D printing of a pessary.
Background
The existing pessaries on the market are all fixed models, but the vagina width, the vagina elasticity and the vagina length of different patients are different, so that not all patients with pelvic organ prolapse can find a proper pessary. The too small pessary can cause the pessary to have poor support to the prolapsed uterus, even the pessary falls out of the vagina, thus the effect of reducing the prolapsed uterus can not be achieved; the overlarge pessary can cause the pessary to have enhanced pressure on the vaginal wall, further cause vaginal mucosal erosion and ulcer, and even cause vesicovaginal fistula, rectovaginal fistula and the like. Therefore, finding a suitable pessary for a patient that matches the individual vaginal condition is not only critical to ameliorating the symptoms of prolapse, but can also reduce the occurrence of complications.
Disclosure of Invention
The invention aims to provide a method for 3D printing of a pessary, which solves the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme:
a method of 3D printing a pessary, comprising the steps of:
s1, size design:
according to the size of the vagina of a patient, a proper pessary size is designed by referring to a pessary model which fails to be worn in the past;
s2, model diagram design:
outputting a stereoscopic model map according to the dimensions designed in step S1 using CAD software;
s3, print processing:
importing the three-dimensional model diagram output in the step S2 into a 3D printer, then injecting printing materials, and taking out after printing to obtain a pessary mold (1) for later use;
s4, injection molding preparation:
and (4) injecting liquid organic silicon into the pessary mould (1) prepared in the step S3, taking out the pessary after curing treatment, and finally carrying out finishing and disinfection treatment.
Further, the printing material in step S3 is composed of the following substances in parts by weight: 90-100 parts of calcium sulfate dihydrate, 2-5 parts of polyvinyl alcohol, 3-6 parts of polypropylene fiber, 25-30 parts of calcined high-aluminum low-iron clay, 1-4 parts of carboxymethyl cellulose, 0.5-1.5 parts of silicon dioxide, 1-3 parts of distilled water, 0.1-0.2 part of sodium dodecyl benzene sulfonate and 0.1-0.3 part of polyvinylpyrrolidone.
Further, a pessary mold groove (2) is further formed in the center of the pessary mold (1) in the step S3; mould fixing holes (3) are further formed in the corners of the pessary mould (1).
Further, the curing process in step S4 is to treat the pessary mold (1) for 48h at a temperature of 60 ℃.
Further, the sterilization process described in step S4 is to expose the pessary to uv radiation for 24 h.
Compared with the prior art, the invention has the beneficial effects that:
the invention provides a method for 3D printing of a pessary, which is simple, can print and manufacture a pessary product suitable for a patient, meets the requirements of customization and targeted therapy, has the advantages of high strength, good biocompatibility, temperature resistance, corrosion resistance and the like, greatly prolongs the service life and safety of the pessary, and has great market competitiveness and popularization and application values.
Drawings
Fig. 1 is a schematic structural view of the pessary mold of the present invention.
In the figure: 1. a pessary mold; 2. a pessary mold slot; 3. and (5) a die fixing hole.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
A method of 3D printing a pessary, comprising the steps of:
s1, size design:
according to the size of the vagina of a patient, a proper pessary size is designed by referring to a pessary model which fails to be worn in the past;
s2, model diagram design:
outputting a stereoscopic model map according to the dimensions designed in step S1 using CAD software;
s3, print processing:
importing the three-dimensional model image output in the step S2 into a 3D printer, then injecting printing materials, and taking out after printing to obtain the pessary mold 1 for later use;
s4, injection molding preparation:
and (4) injecting liquid organic silicon into the pessary mold 1 prepared in the step S3, taking out the pessary after curing treatment, and finally carrying out finishing and disinfection treatment.
The printing material in the step S3 is composed of the following substances in parts by weight: 90 parts of calcium sulfate dihydrate, 2 parts of polyvinyl alcohol, 3 parts of polypropylene fiber, 25 parts of calcined high-aluminum low-iron clay, 1 part of carboxymethyl cellulose, 0.5 part of silicon dioxide, 1 part of distilled water, 0.1 part of sodium dodecyl benzene sulfonate and 0.1 part of polyvinylpyrrolidone.
A pessary mold groove 2 is also arranged in the center of the pessary mold 1 in the step S3; mould fixing holes 3 are further formed in the corners of the pessary mould 1.
The curing process in step S4 is to subject the pessary mold 1 to a temperature of 60 ℃ for 48 h.
The sterilization process in step S4 is to expose the pessary to ultraviolet radiation for 24 hours.
Example 2
A method of 3D printing a pessary, comprising the steps of:
s1, size design:
according to the size of the vagina of a patient, a proper pessary size is designed by referring to a pessary model which fails to be worn in the past;
s2, model diagram design:
outputting a stereoscopic model map according to the dimensions designed in step S1 using CAD software;
s3, print processing:
importing the three-dimensional model image output in the step S2 into a 3D printer, then injecting printing materials, and taking out after printing to obtain the pessary mold 1 for later use;
s4, injection molding preparation:
and (4) injecting liquid organic silicon into the pessary mold 1 prepared in the step S3, taking out the pessary after curing treatment, and finally carrying out finishing and disinfection treatment.
The printing material in the step S3 is composed of the following substances in parts by weight: 95 parts of calcium sulfate dihydrate, 4 parts of polyvinyl alcohol, 5 parts of polypropylene fiber, 28 parts of calcined high-aluminum low-iron clay, 3 parts of carboxymethyl cellulose, 1 part of silicon dioxide, 2 parts of distilled water, 0.15 part of sodium dodecyl benzene sulfonate and 0.2 part of polyvinylpyrrolidone.
A pessary mold groove 2 is also arranged in the center of the pessary mold 1 in the step S3; mould fixing holes 3 are further formed in the corners of the pessary mould 1.
The curing process in step S4 is to subject the pessary mold 1 to a temperature of 60 ℃ for 48 h.
The sterilization process in step S4 is to expose the pessary to ultraviolet radiation for 24 hours.
Example 3
A method of 3D printing a pessary, comprising the steps of:
s1, size design:
according to the size of the vagina of a patient, a proper pessary size is designed by referring to a pessary model which fails to be worn in the past;
s2, model diagram design:
outputting a stereoscopic model map according to the dimensions designed in step S1 using CAD software;
s3, print processing:
importing the three-dimensional model image output in the step S2 into a 3D printer, then injecting printing materials, and taking out after printing to obtain the pessary mold 1 for later use;
s4, injection molding preparation:
and (4) injecting liquid organic silicon into the pessary mold 1 prepared in the step S3, taking out the pessary after curing treatment, and finally carrying out finishing and disinfection treatment.
The printing material in the step S3 is composed of the following substances in parts by weight: 100 parts of calcium sulfate dihydrate, 5 parts of polyvinyl alcohol, 6 parts of polypropylene fiber, 30 parts of calcined high-aluminum low-iron clay, 4 parts of carboxymethyl cellulose, 1.5 parts of silicon dioxide, 3 parts of distilled water, 0.2 part of sodium dodecyl benzene sulfonate and 0.3 part of polyvinylpyrrolidone.
A pessary mold groove 2 is also arranged in the center of the pessary mold 1 in the step S3; mould fixing holes 3 are further formed in the corners of the pessary mould 1.
The curing process in step S4 is to subject the pessary mold 1 to a temperature of 60 ℃ for 48 h.
The sterilization process in step S4 is to expose the pessary to ultraviolet radiation for 24 hours.
Above-mentioned uterus holds in palm mould 1 and has illustrated half mould in the picture, and half mould structural feature is the same, will be two when using together earlier, then with screw etc. through mould fixed orifices 3 with the mould fixed good can.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.

Claims (5)

1. A method of 3D printing a pessary, comprising the steps of:
s1, size design:
according to the size of the vagina of a patient, a proper pessary size is designed by referring to a pessary model which fails to be worn in the past;
s2, model diagram design:
outputting a stereoscopic model map according to the dimensions designed in step S1 using CAD software;
s3, print processing:
importing the three-dimensional model diagram output in the step S2 into a 3D printer, then injecting printing materials, and taking out after printing to obtain a pessary mold (1) for later use;
s4, injection molding preparation:
and (4) injecting liquid organic silicon into the pessary mould (1) prepared in the step S3, taking out the pessary after curing treatment, and finally carrying out finishing and disinfection treatment.
2. A method for 3D printing a pessary according to claim 1, wherein the printing material in step S3 is composed of the following materials by weight: 90-100 parts of calcium sulfate dihydrate, 2-5 parts of polyvinyl alcohol, 3-6 parts of polypropylene fiber, 25-30 parts of calcined high-aluminum low-iron clay, 1-4 parts of carboxymethyl cellulose, 0.5-1.5 parts of silicon dioxide, 1-3 parts of distilled water, 0.1-0.2 part of sodium dodecyl benzene sulfonate and 0.1-0.3 part of polyvinylpyrrolidone.
3. A method for 3D printing a pessary according to claim 1, wherein the pessary mold (1) in step S3 is further provided with a pessary mold slot (2) in the center; mould fixing holes (3) are further formed in the corners of the pessary mould (1).
4. A method for 3D printing a pessary according to claim 1, wherein the curing process in step S4 is to place the pessary mold (1) at a temperature of 60 ℃ for 48 h.
5. A method for 3D printing a pessary according to claim 1, wherein the sterilizing process in step S4 is irradiating the pessary under ultraviolet light for 24 h.
CN202110351207.3A 2021-03-31 2021-03-31 Method for 3D printing of pessary Pending CN112939560A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023090655A1 (en) * 2021-11-22 2023-05-25 가톨릭대학교 산학협력단 Manufacturing system and manufacturing method for customized pessary by using 3d printer and patient-customized pessary manufactured thereby

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106220197A (en) * 2016-07-26 2016-12-14 苏州秉创科技有限公司 A kind of fire safe type 3D printed material
CN206080787U (en) * 2016-06-12 2017-04-12 武汉永创佳生物科技有限公司 Prevent prolapse of uterus system
US20170182708A1 (en) * 2015-12-09 2017-06-29 Autodesk, Inc. Multi-material stereolithographic three dimensional printing
KR20180049712A (en) * 2016-11-03 2018-05-11 포항공과대학교 산학협력단 Wet 3D cell printing using decellularized extracellular matrix
CN108790027A (en) * 2018-05-23 2018-11-13 上海蓓蕊医疗科技有限公司 A kind of pessary production technology
CN110974521A (en) * 2019-11-25 2020-04-10 华中科技大学同济医学院附属协和医院 3D printing model for preventing uterine cavity from being sticky and manufacturing method
CN111214283A (en) * 2020-03-17 2020-06-02 中山大学孙逸仙纪念医院 Amniotic sac protection device based on 3D printing and preparation method thereof
CN111246824A (en) * 2017-09-18 2020-06-05 德瑞克·席安 Method and system for assembling vaginal treatment device

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170182708A1 (en) * 2015-12-09 2017-06-29 Autodesk, Inc. Multi-material stereolithographic three dimensional printing
CN206080787U (en) * 2016-06-12 2017-04-12 武汉永创佳生物科技有限公司 Prevent prolapse of uterus system
CN106220197A (en) * 2016-07-26 2016-12-14 苏州秉创科技有限公司 A kind of fire safe type 3D printed material
KR20180049712A (en) * 2016-11-03 2018-05-11 포항공과대학교 산학협력단 Wet 3D cell printing using decellularized extracellular matrix
CN111246824A (en) * 2017-09-18 2020-06-05 德瑞克·席安 Method and system for assembling vaginal treatment device
CN108790027A (en) * 2018-05-23 2018-11-13 上海蓓蕊医疗科技有限公司 A kind of pessary production technology
CN110974521A (en) * 2019-11-25 2020-04-10 华中科技大学同济医学院附属协和医院 3D printing model for preventing uterine cavity from being sticky and manufacturing method
CN111214283A (en) * 2020-03-17 2020-06-02 中山大学孙逸仙纪念医院 Amniotic sac protection device based on 3D printing and preparation method thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023090655A1 (en) * 2021-11-22 2023-05-25 가톨릭대학교 산학협력단 Manufacturing system and manufacturing method for customized pessary by using 3d printer and patient-customized pessary manufactured thereby
KR20230075291A (en) * 2021-11-22 2023-05-31 가톨릭대학교 산학협력단 A manufacturing system and method of customized pessary using 3D printer, and patient-customized pessary manufactured thereby
KR102640948B1 (en) 2021-11-22 2024-02-23 가톨릭대학교 산학협력단 A manufacturing system and method of customized pessary using 3D printer, and patient-customized pessary manufactured thereby

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Application publication date: 20210611