CN112933199A - A topical patch for stopping smoking and clearing away lung-heat, and its preparation method - Google Patents
A topical patch for stopping smoking and clearing away lung-heat, and its preparation method Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/739—Sanguisorba (burnet)
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/55—Glands not provided for in groups A61K35/22 - A61K35/545, e.g. thyroids, parathyroids or pineal glands
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/78—Saururaceae (Lizard's-tail family)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
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Abstract
The invention discloses an external patch for quitting smoking and clearing away the lung-heat, which comprises a breathable layer, a heat insulation layer, a non-woven fabric layer and a diaphragm layer which are sequentially connected from the outer side to the inner side; adhesive tapes are respectively adhered to two ends of the heat insulation layer, and a paper tape is adhered to one side of each adhesive tape, which is far away from the breathable layer; the non-woven fabric layer is coated with a medicament for quitting smoking and clearing away the lung-heat; the medicament for stopping smoking and clearing lung comprises the following components in parts by mass: 10-15 parts of garden burnet, 5-8 parts of houttuynia cordata, 10-12 parts of mint, 13-16 parts of musk, 10-13 parts of storax, 8-13 parts of radix curcumae, 20-25 parts of polypropylene and 15-20 parts of ethanol. The invention also discloses a preparation method of the external patch for smoking cessation and lung clearing. The invention has the following beneficial effects: 1. no side effect, good smoking cessation effect and high success rate; 2. when the medicament is applied to the skin, the contact area of the medicament and the skin is small, and the medicament is easy to tear off; 3. the stability of the bonding is good.
Description
Technical Field
The invention belongs to the field of medicaments, and particularly relates to an external patch for smoking cessation and lung clearing and a preparation method thereof.
Background
Studies have shown that 25 life-threatening and health-threatening diseases, including lung cancer and other cancers, heart disease, and lung disorders, are associated with smoking. These diseases can be prevented or the risk of the diseases can be reduced by smoking cessation. The number of people dying from diseases associated with smoking annually is up to 350 ten thousand. If no action is taken, the number of deaths per year from smoking-related diseases will increase to 1000 ten thousand by 2030.
The smoking cessation paste adopts nicotine replacement therapy recommended by the world health organization and the American Ministry of health to stop smoking, so that smokers can quickly get rid of the dependence on cigarettes, the especially difficult problem of smoking cessation syndrome is effectively solved, and the high withdrawal rate of the smoking cessation paste wins the worlds smoking control organization and the well-known experts, and is popular in the world and abroad. The smoking cessation paste mainly has the following functions: smoking cessation, smoking reduction and cigarette replacement.
However, the existing smoking cessation plaster is similar to plaster, is not convenient to tear off after being pasted, and has more chemical synthetic medicaments as internal medicaments, thereby causing certain injury to human bodies when in use.
Disclosure of Invention
The purpose of the invention is as follows: aiming at the defects of the prior art, the invention provides an external patch for smoking cessation and lung clearing and a preparation method thereof.
The technical scheme is as follows: a topical patch for stopping smoking and clearing lung-heat comprises a gas permeable layer, a heat insulating layer, a non-woven fabric layer, and a diaphragm layer sequentially connected from outer side to inner side;
adhesive tapes are respectively adhered to two ends of the heat insulation layer, and a paper tape is adhered to one side of each adhesive tape, which is far away from the breathable layer;
the non-woven fabric layer is coated with a medicament for smoking cessation and lung clearing;
the medicament for stopping smoking and clearing lung comprises the following components in parts by mass: 10-15 parts of garden burnet, 5-8 parts of houttuynia cordata, 10-12 parts of mint, 13-16 parts of musk, 10-13 parts of storax, 8-13 parts of radix curcumae, 20-25 parts of polypropylene and 15-20 parts of ethanol.
Preferably, the breathable layer is formed by extruding polyethylene, and a plurality of breathable holes are uniformly formed in the surface of the breathable layer.
Preferably, the heat insulation layer is made of asbestos.
Preferably, the membrane layer is extruded from polyethylene terephthalate.
A preparation method of an external patch for stopping smoking and clearing lung heat comprises the following steps:
s1, grinding garden burnet root, heartleaf houttuynia herb, mint, musk, storax and turmeric root-tuber into powder according to the formula amount, and standing for later use;
s2, taking the polypropylene particles according to the formula amount, heating until the polypropylene particles are dissolved, adding ethanol according to the formula amount, uniformly stirring, then adding the traditional Chinese medicine powder obtained in the step S1, and continuously stirring to obtain uniformly mixed liquid;
s3, cooling the uniformly mixed liquid obtained in the step S2 to 120-150 ℃, uniformly coating the uniformly mixed liquid on non-woven fabrics, and putting the non-woven fabrics into a drying oven to room temperature;
s4, extruding and molding a polyethylene terephthalate material to obtain a sheet-shaped diaphragm layer;
s5, extruding and molding polyethylene to obtain a sheet-shaped breathable layer;
and S6, sequentially bonding the air-permeable layer, the heat-insulating layer, the non-woven fabric layer and the diaphragm layer, and bonding adhesive tapes at two ends of the air-permeable layer to complete the preparation.
Preferably, the thickness ratio of the breathable layer to the thermal insulation layer to the non-woven fabric layer to the diaphragm layer is 1:1:2: 1.
The invention discloses an external patch for quitting smoking and clearing away the lung-heat and a preparation method thereof, and the external patch has the following beneficial effects:
1. the medicament adopts the traditional Chinese medicinal materials of sanguisorba, houttuynia cordata, mint, musk, storax and radix curcumae, has reasonable formula, has no side effect in the smoking cessation process, has the functions of clearing heat and detoxicating, cooling blood and relieving dryness, has good smoking cessation effect and high success rate, stimulates acupuncture points, inhibits the human body, can reduce the smoking desire of people, and relieves the psychological symptoms such as dysphoria, anxiety and the like when smoking cessation;
2. the membrane layer is bonded on the non-woven fabric layer coated with the medicament, so that when the medicament is applied to the skin, the contact area between the medicament and the skin can be reduced, the over-tight bonding is prevented, and the membrane layer is not easy to tear;
3. set up the gluing strip at insulating layer both ends, both ends are torn down the paper tape and can be glued on skin, can guarantee the stability of bonding, reduce the bonding area simultaneously, reduce the painful sense of skin when tearing down.
Drawings
FIG. 1 is a schematic view of the structure of an external patch for stopping smoking and clearing away the lung-heat provided by the invention;
in the figure: 1. a breathable layer; 2. a thermal insulation layer; 3. a non-woven fabric layer; 4. a separator layer;
5. an adhesive tape; 6. a paper strap.
The specific implementation mode is as follows:
the following describes in detail specific embodiments of the present invention.
The external patch for smoking cessation and lung clearing according to the embodiment of the present invention will be described in detail with reference to fig. 1.
Detailed description of the preferred embodiment 1
A topical patch for stopping smoking and clearing lung-heat comprises a gas permeable layer 1, a heat insulating layer 2, a non-woven fabric layer 3, and a diaphragm layer 4 connected in sequence from outer side to inner side;
adhesive tapes 5 are respectively adhered to two ends of the heat insulation layer 2, and a paper tape 6 is adhered to one side of each adhesive tape 5, which is far away from the breathable layer 1;
the non-woven fabric layer 3 is coated with a medicament for smoking cessation and lung clearing;
the medicament for stopping smoking and clearing lung comprises the following components in parts by mass: 10 parts of garden burnet, 5 parts of houttuynia cordata, 10 parts of mint, 13 parts of musk, 10 parts of storax, 8 parts of radix curcumae, 20 parts of polypropylene and 150 parts of ethanol.
Preferably, the breathable layer 1 is formed by extruding polyethylene, and a plurality of breathable holes are uniformly formed in the surface of the breathable layer 1.
Preferably, the insulating layer 2 is made of asbestos.
Preferably, the membrane layer 4 is extruded from polyethylene terephthalate.
A preparation method of an external patch for stopping smoking and clearing lung heat comprises the following steps:
s1, grinding garden burnet root, heartleaf houttuynia herb, mint, musk, storax and turmeric root-tuber into powder according to the formula amount, and standing for later use;
s2, taking the polypropylene particles according to the formula amount, heating until the polypropylene particles are dissolved, adding ethanol according to the formula amount, uniformly stirring, then adding the traditional Chinese medicine powder obtained in the step S1, and continuously stirring to obtain uniformly mixed liquid;
s3, cooling the uniformly mixed liquid obtained in the step S2 to 120 ℃, uniformly coating the uniformly mixed liquid on non-woven fabrics, and putting the non-woven fabrics into a drying oven to room temperature;
s4, extruding and molding a polyethylene terephthalate material to obtain a sheet-shaped diaphragm layer;
s5, extruding and molding polyethylene to obtain a sheet-shaped breathable layer;
and S6, sequentially bonding the breathable layer, the heat insulation layer, the non-woven fabric layer and the diaphragm layer, and bonding adhesive tapes at two ends of the breathable layer to complete the preparation.
Preferably, the thickness ratio of the air-permeable layer to the heat-insulating layer to the non-woven fabric layer to the membrane layer is 1:1:2: 1.
Specific example 2
A topical patch for stopping smoking and clearing lung-heat comprises a gas permeable layer 1, a heat insulating layer 2, a non-woven fabric layer 3, and a diaphragm layer 4 connected in sequence from outer side to inner side;
adhesive tapes 5 are respectively adhered to two ends of the heat insulation layer 2, and a paper tape 6 is adhered to one side of each adhesive tape 5, which is far away from the breathable layer 1;
the non-woven fabric layer 3 is coated with a medicament for smoking cessation and lung clearing;
the medicament for stopping smoking and clearing lung comprises the following components in parts by mass: 13 parts of garden burnet, 6 parts of heartleaf houttuynia herb, 11 parts of mint, 15 parts of musk, 12 parts of storax, 10 parts of turmeric root-tuber, 22 parts of polypropylene and 18 parts of ethanol.
Preferably, the breathable layer 1 is formed by extruding polyethylene, and a plurality of breathable holes are uniformly formed in the surface of the breathable layer 1.
Preferably, the insulating layer 2 is made of asbestos.
Preferably, the membrane layer 4 is extruded from polyethylene terephthalate.
A preparation method of an external patch for stopping smoking and clearing lung heat comprises the following steps:
s1, grinding garden burnet root, heartleaf houttuynia herb, mint, musk, storax and turmeric root-tuber into powder according to the formula amount, and standing for later use;
s2, taking the polypropylene particles according to the formula amount, heating until the polypropylene particles are dissolved, adding ethanol according to the formula amount, uniformly stirring, then adding the traditional Chinese medicine powder obtained in the step S1, and continuously stirring to obtain uniformly mixed liquid;
s3, cooling the uniformly mixed liquid obtained in the step S2 to 130 ℃, uniformly coating the uniformly mixed liquid on non-woven fabrics, and putting the non-woven fabrics into a drying oven to room temperature;
s4, extruding and molding a polyethylene terephthalate material to obtain a sheet-shaped diaphragm layer;
s5, extruding and molding polyethylene to obtain a sheet-shaped breathable layer;
and S6, sequentially bonding the breathable layer, the heat insulation layer, the non-woven fabric layer and the diaphragm layer, and bonding adhesive tapes at two ends of the breathable layer to complete the preparation.
Preferably, the thickness ratio of the air-permeable layer to the heat-insulating layer to the non-woven fabric layer to the membrane layer is 1:1:2: 1.
Specific example 3
A topical patch for stopping smoking and clearing lung-heat comprises a gas permeable layer 1, a heat insulating layer 2, a non-woven fabric layer 3, and a diaphragm layer 4 connected in sequence from outer side to inner side;
adhesive tapes 5 are respectively adhered to two ends of the heat insulation layer 2, and a paper tape 6 is adhered to one side of each adhesive tape 5, which is far away from the breathable layer 1;
the non-woven fabric layer 3 is coated with a medicament for smoking cessation and lung clearing;
the medicament for stopping smoking and clearing lung comprises the following components in parts by mass: 15 parts of garden burnet, 8 parts of houttuynia cordata, 12 parts of mint, 16 parts of musk, 13 parts of storax, 13 parts of radix curcumae, 25 parts of polypropylene and 20 parts of ethanol.
Preferably, the breathable layer 1 is formed by extruding polyethylene, and a plurality of breathable holes are uniformly formed in the surface of the breathable layer 1.
Preferably, the insulating layer 2 is made of asbestos.
Preferably, the membrane layer 4 is extruded from polyethylene terephthalate.
A preparation method of an external patch for stopping smoking and clearing lung heat comprises the following steps:
s1, grinding garden burnet root, heartleaf houttuynia herb, mint, musk, storax and turmeric root-tuber into powder according to the formula amount, and standing for later use;
s2, taking the polypropylene particles according to the formula amount, heating until the polypropylene particles are dissolved, adding ethanol according to the formula amount, uniformly stirring, then adding the traditional Chinese medicine powder obtained in the step S1, and continuously stirring to obtain uniformly mixed liquid;
s3, cooling the uniformly mixed liquid obtained in the step S2 to 150 ℃, uniformly coating the uniformly mixed liquid on non-woven fabrics, and putting the non-woven fabrics into a drying oven to room temperature;
s4, extruding and molding a polyethylene terephthalate material to obtain a sheet-shaped diaphragm layer;
s5, extruding and molding polyethylene to obtain a sheet-shaped breathable layer;
and S6, sequentially bonding the breathable layer, the heat insulation layer, the non-woven fabric layer and the diaphragm layer, and bonding adhesive tapes at two ends of the breathable layer to complete the preparation.
Preferably, the thickness ratio of the air-permeable layer to the heat-insulating layer to the non-woven fabric layer to the membrane layer is 1:1:2: 1.
When the patch prepared in the above specific embodiment 1-3 is used, the whole patch is heated to 165 ℃ by heating with an alcohol lamp or other heating devices, the medicament is dissolved, the paper tape on the adhesive tape is torn off, and the adhesive tape is stuck to the acupuncture points such as the wrist for 20-25 min.
The embodiments of the present invention have been described in detail. However, the present invention is not limited to the above-described embodiments, and various changes can be made within the knowledge of those skilled in the art without departing from the spirit of the present invention.
Claims (6)
1. An external patch for stopping smoking and clearing lung is characterized by comprising a breathable layer, a heat insulation layer, a non-woven fabric layer and a diaphragm layer which are sequentially connected from the outer side to the inner side;
adhesive tapes are respectively adhered to two ends of the heat insulation layer, and a paper tape is adhered to one side of each adhesive tape, which is far away from the breathable layer;
the non-woven fabric layer is coated with a medicament for smoking cessation and lung clearing;
the medicament for stopping smoking and clearing lung comprises the following components in parts by mass: 10-15 parts of garden burnet, 5-8 parts of houttuynia cordata, 10-12 parts of mint, 13-16 parts of musk, 10-13 parts of storax, 8-13 parts of radix curcumae, 20-25 parts of polypropylene and 15-20 parts of ethanol.
2. The patch for external use for stopping smoking and clearing away the lung-heat as claimed in claim 1, wherein the air-permeable layer is formed by extruding polyethylene, and a plurality of air-permeable holes are uniformly formed on the surface of the air-permeable layer.
3. The patch for external use for smoking cessation and lung clearing as claimed in claim 1, wherein the insulation layer is made of asbestos.
4. The patch for external use for stopping smoking and clearing away the lung-heat according to claim 1, wherein said membrane layer is extruded from polyethylene terephthalate.
5. A preparation method of an external patch for smoking cessation and lung clearing is characterized by comprising the following steps:
s1, grinding garden burnet root, heartleaf houttuynia herb, mint, musk, storax and turmeric root-tuber into powder according to the formula amount, and standing for later use;
s2, taking the polypropylene particles according to the formula amount, heating until the polypropylene particles are dissolved, adding ethanol according to the formula amount, uniformly stirring, then adding the traditional Chinese medicine powder obtained in the step S1, and continuously stirring to obtain uniformly mixed liquid;
s3, cooling the uniformly mixed liquid obtained in the step S2 to 120-150 ℃, uniformly coating the uniformly mixed liquid on non-woven fabrics, and putting the non-woven fabrics into a drying oven to room temperature;
s4, extruding and molding a polyethylene terephthalate material to obtain a sheet-shaped diaphragm layer;
s5, extruding and molding polyethylene to obtain a sheet-shaped breathable layer;
and S6, sequentially bonding the air-permeable layer, the heat-insulating layer, the non-woven fabric layer and the diaphragm layer, and bonding adhesive tapes at two ends of the air-permeable layer to complete the preparation.
6. The method for preparing an external patch for stopping smoking and clearing away lung-heat according to claim 5, wherein the thickness ratio of the air-permeable layer, the heat-insulating layer, the non-woven fabric layer and the diaphragm layer is 1:1:2: 1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110154881.2A CN112933199A (en) | 2021-02-04 | 2021-02-04 | A topical patch for stopping smoking and clearing away lung-heat, and its preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110154881.2A CN112933199A (en) | 2021-02-04 | 2021-02-04 | A topical patch for stopping smoking and clearing away lung-heat, and its preparation method |
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| CN112933199A true CN112933199A (en) | 2021-06-11 |
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| CN202110154881.2A Pending CN112933199A (en) | 2021-02-04 | 2021-02-04 | A topical patch for stopping smoking and clearing away lung-heat, and its preparation method |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107468413A (en) * | 2017-06-13 | 2017-12-15 | 吴添娣 | Medicine hot compress paste for anti-inflammatory analgetic |
| CN108567766A (en) * | 2018-06-05 | 2018-09-25 | 史锐 | A kind of ventilation patch and preparation method thereof |
| CN109758564A (en) * | 2018-12-30 | 2019-05-17 | 无锡华粹堂健康管理有限公司 | A kind of Chinese medicine foot patch |
| CN210185849U (en) * | 2019-04-25 | 2020-03-27 | 广东康美芝医疗用品科技有限公司 | Anti-seepage non-walking acupuncture point fixing patch |
| CN211157436U (en) * | 2019-09-11 | 2020-08-04 | 江苏省中医药研究院 | A medicinal plaster for treating insomnia on sole of foot |
-
2021
- 2021-02-04 CN CN202110154881.2A patent/CN112933199A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107468413A (en) * | 2017-06-13 | 2017-12-15 | 吴添娣 | Medicine hot compress paste for anti-inflammatory analgetic |
| CN108567766A (en) * | 2018-06-05 | 2018-09-25 | 史锐 | A kind of ventilation patch and preparation method thereof |
| CN109758564A (en) * | 2018-12-30 | 2019-05-17 | 无锡华粹堂健康管理有限公司 | A kind of Chinese medicine foot patch |
| CN210185849U (en) * | 2019-04-25 | 2020-03-27 | 广东康美芝医疗用品科技有限公司 | Anti-seepage non-walking acupuncture point fixing patch |
| CN211157436U (en) * | 2019-09-11 | 2020-08-04 | 江苏省中医药研究院 | A medicinal plaster for treating insomnia on sole of foot |
Non-Patent Citations (2)
| Title |
|---|
| 鄢海燕等: "《药剂学》", 31 January 2018, 江苏凤凰科学技术出版社 * |
| 顾正荣: ""中药穴位贴敷与心理疏导结合戒烟疗法临床观察"", 《世界中西医结合杂志》 * |
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Application publication date: 20210611 |
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