CN112826882A - Production process of traditional Chinese medicine type band-aid with disinfection and bacteriostasis functions - Google Patents
Production process of traditional Chinese medicine type band-aid with disinfection and bacteriostasis functions Download PDFInfo
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- CN112826882A CN112826882A CN202110059605.8A CN202110059605A CN112826882A CN 112826882 A CN112826882 A CN 112826882A CN 202110059605 A CN202110059605 A CN 202110059605A CN 112826882 A CN112826882 A CN 112826882A
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- 239000003814 drug Substances 0.000 title claims abstract description 45
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 30
- 238000004659 sterilization and disinfection Methods 0.000 title claims abstract description 30
- 239000000853 adhesive Substances 0.000 claims abstract description 49
- 230000001070 adhesive effect Effects 0.000 claims abstract description 49
- 239000004744 fabric Substances 0.000 claims abstract description 38
- 230000000474 nursing effect Effects 0.000 claims abstract description 38
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 34
- 238000002156 mixing Methods 0.000 claims abstract description 31
- 238000010030 laminating Methods 0.000 claims abstract description 29
- 239000002994 raw material Substances 0.000 claims abstract description 25
- 235000005187 Taraxacum officinale ssp. officinale Nutrition 0.000 claims abstract description 17
- 239000009910 sargent gloryvine Substances 0.000 claims abstract description 17
- 240000000691 Houttuynia cordata Species 0.000 claims abstract description 16
- 235000013719 Houttuynia cordata Nutrition 0.000 claims abstract description 16
- 241001116389 Aloe Species 0.000 claims abstract description 13
- 235000011399 aloe vera Nutrition 0.000 claims abstract description 13
- 239000004088 foaming agent Substances 0.000 claims abstract description 13
- 241000196324 Embryophyta Species 0.000 claims abstract description 12
- 240000004824 Trimezia steyermarkii Species 0.000 claims abstract description 12
- 239000009136 dragon's blood Substances 0.000 claims abstract description 12
- 229920002472 Starch Polymers 0.000 claims abstract description 11
- 235000019698 starch Nutrition 0.000 claims abstract description 11
- 239000008107 starch Substances 0.000 claims abstract description 11
- 239000007788 liquid Substances 0.000 claims description 27
- 239000004745 nonwoven fabric Substances 0.000 claims description 25
- 238000007654 immersion Methods 0.000 claims description 20
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 18
- 241000245665 Taraxacum Species 0.000 claims description 16
- 241000382455 Angelica sinensis Species 0.000 claims description 15
- 238000010438 heat treatment Methods 0.000 claims description 15
- 238000003756 stirring Methods 0.000 claims description 15
- 238000004026 adhesive bonding Methods 0.000 claims description 11
- 238000000034 method Methods 0.000 claims description 11
- 239000012153 distilled water Substances 0.000 claims description 10
- 239000011505 plaster Substances 0.000 claims description 8
- 229920000297 Rayon Polymers 0.000 claims description 7
- 239000003292 glue Substances 0.000 claims description 7
- 238000002360 preparation method Methods 0.000 claims description 7
- 229920000742 Cotton Polymers 0.000 claims description 5
- 239000004831 Hot glue Substances 0.000 claims description 5
- 238000013329 compounding Methods 0.000 claims description 5
- 238000001035 drying Methods 0.000 claims description 5
- 238000000465 moulding Methods 0.000 claims description 5
- 238000004806 packaging method and process Methods 0.000 claims description 5
- 230000001954 sterilising effect Effects 0.000 claims description 5
- 229920002907 Guar gum Polymers 0.000 claims description 3
- 239000003945 anionic surfactant Substances 0.000 claims description 3
- 238000003491 array Methods 0.000 claims description 3
- 239000003995 emulsifying agent Substances 0.000 claims description 3
- 239000000665 guar gum Substances 0.000 claims description 3
- 229960002154 guar gum Drugs 0.000 claims description 3
- 235000010417 guar gum Nutrition 0.000 claims description 3
- 230000029663 wound healing Effects 0.000 abstract description 6
- 229940056582 human hair preparation Drugs 0.000 abstract description 5
- 208000035143 Bacterial infection Diseases 0.000 abstract description 4
- 208000022362 bacterial infectious disease Diseases 0.000 abstract description 4
- 239000004480 active ingredient Substances 0.000 abstract description 3
- 238000005265 energy consumption Methods 0.000 abstract description 2
- 230000002421 anti-septic effect Effects 0.000 abstract 2
- 241000213006 Angelica dahurica Species 0.000 abstract 1
- 240000001949 Taraxacum officinale Species 0.000 abstract 1
- 238000005516 engineering process Methods 0.000 abstract 1
- 238000003913 materials processing Methods 0.000 abstract 1
- 206010052428 Wound Diseases 0.000 description 24
- 208000027418 Wounds and injury Diseases 0.000 description 24
- 239000004698 Polyethylene Substances 0.000 description 15
- 230000000694 effects Effects 0.000 description 7
- 230000009286 beneficial effect Effects 0.000 description 4
- 229940126680 traditional chinese medicines Drugs 0.000 description 4
- 231100000344 non-irritating Toxicity 0.000 description 3
- -1 polyethylene Polymers 0.000 description 3
- 229920000573 polyethylene Polymers 0.000 description 3
- 239000011148 porous material Substances 0.000 description 3
- 238000002791 soaking Methods 0.000 description 3
- 208000032843 Hemorrhage Diseases 0.000 description 2
- 239000002174 Styrene-butadiene Substances 0.000 description 2
- 239000013543 active substance Substances 0.000 description 2
- 230000000740 bleeding effect Effects 0.000 description 2
- 238000009395 breeding Methods 0.000 description 2
- 230000001488 breeding effect Effects 0.000 description 2
- 239000002085 irritant Substances 0.000 description 2
- 231100000021 irritant Toxicity 0.000 description 2
- 230000000622 irritating effect Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 239000011115 styrene butadiene Substances 0.000 description 2
- 229920003048 styrene butadiene rubber Polymers 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 description 1
- 239000005977 Ethylene Substances 0.000 description 1
- 208000033809 Suppuration Diseases 0.000 description 1
- 206010051373 Wound haemorrhage Diseases 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 238000003892 spreading Methods 0.000 description 1
Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive bandages or dressings
- A61F13/0276—Apparatus or processes for manufacturing adhesive dressings or bandages
- A61F13/0289—Apparatus or processes for manufacturing adhesive dressings or bandages manufacturing of adhesive dressings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7076—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
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Abstract
The invention discloses a production process of a traditional Chinese medicine type band-aid with disinfection and bacteriostasis, and relates to the field of daily pharmaceuticals. The production process of the traditional Chinese medicine type adhesive bandage with disinfection and bacteriostasis comprises a nursing layer and an attaching outer layer, wherein the nursing layer comprises the following components in parts by weight: 150 parts of base cloth, 28-38 parts of sargentgloryvine stem, 23-37 parts of ethanol, 15-29 parts of aloe gel, 12-18 parts of houttuynia cordata, 12-16 parts of dragon's blood, 8-16 parts of Chinese angelica, 6-12 parts of plant ash, 5-15 parts of starch adhesive, 3-5 parts of dandelion flower, 2-2.8 parts of crinis carbonisatus and 1.4-1.8 parts of foaming agent. This production technology of antiseptic traditional chinese medicine type band-aid adopts the mode of low temperature mixing to traditional chinese medicine raw materials processing, has reduced the loss of active ingredient in the traditional chinese medicine, has reduced the energy consumption, still perforates this nursing layer and the both sides in laminating outer clearance, and the guarantee circulation of air cooperates the antiseptic utility of disinfection, prevents bacterial infection for wound healing speed.
Description
Technical Field
The invention relates to the technical field of daily pharmaceuticals, in particular to a production process of a traditional Chinese medicine type band-aid with disinfection and bacteriostasis.
Background
The adhesive bandage is a medical article which is often used in daily life of people, can help stop bleeding and prevent wound from being injured again when skin is wounded, however, the wound pastes on the market only inhibit wound bleeding in a form of attaching, the bleeding at the wound is not caused, however, the bacteria in the wound dressing are easy to breed in a sealed damp and hot environment, the wound healing speed is delayed, the wound can be suppurative in serious cases, the using effect is poor, the traditional Chinese medicine type wound dressing is one of the common wound dressings in the market at present, the traditional Chinese medicine components can assist wound healing, but the wound plaster is produced by processing traditional Chinese medicine raw materials in a high-temperature mixing mode, the loss of effective components is more, which affects the quality of finished products, and the traditional Chinese medicine components are probably more irritant, the direct contact with the wound can aggravate the pain of the wounded, has poor practicability and is not beneficial to popularization and use.
Disclosure of Invention
Technical problem to be solved
Aiming at the defects of the prior art, the invention provides a production process of a traditional Chinese medicine type adhesive bandage with disinfection, antibiosis, natural non-irritating disinfection and bacteriostasis.
(II) technical scheme
In order to achieve the purpose, the invention provides the following technical scheme:
a production process of a traditional Chinese medicine type adhesive bandage with disinfection and bacteriostasis comprises a nursing layer and an attaching outer layer, wherein the nursing layer comprises the following components in parts by weight: 150 parts of base cloth, 28-38 parts of sargentgloryvine stem, 23-37 parts of ethanol, 15-29 parts of aloe gel, 12-18 parts of houttuynia cordata, 12-16 parts of dragon's blood, 8-16 parts of Chinese angelica, 6-12 parts of plant ash, 5-15 parts of starch adhesive, 3-5 parts of dandelion flower, 2-2.8 parts of carbonized hair and 1.4-1.8 parts of foaming agent.
Preferably, the attaching outer layer is formed by compounding a PE breathable film, an ES hot air non-woven fabric, release paper and viscose glue.
Preferably, the base cloth is made of absorbent cotton, and the concentration of ethanol is 68%.
Preferably, the sargentgloryvine stem, the houttuynia cordata, the angelica sinensis and the dandelion flowers are all dry products after being cleaned and dried.
Preferably, the method comprises the following steps:
s1, preparation of a care solution: putting the sargentgloryvine stem, the houttuynia cordata, the dragon's blood, the angelica sinensis and the dandelion flower in corresponding parts into a wall breaking machine for crushing and mixing, wherein the rotating speed of wall breaking blades is 1200-1400 revolutions per minute, after mixing for 10 minutes, pouring the plant ash, the starch adhesive and distilled water which is 0.4-0.6 time of the sum of the parts of the raw materials into the wall breaking machine in sequence, controlling the rotating speed of the blades of the wall breaking machine to be increased to 1600-1900 revolutions per minute, after continuously mixing for 10-20 minutes, pouring out the mixed colloidal liquid from the wall breaking machine to obtain the care solution.
S2, finishing the care layer: pouring ethanol, aloe gel and distilled water of which the parts are 1 time of the sum of the two raw materials into a liquid containing tank in sequence, heating the raw materials and the water to 35-45 ℃, keeping the temperature, putting the foaming agent of which the parts are the same into an immersion tank, stirring and mixing at the stirring speed of 120 revolutions per minute, heating and mixing for 20 minutes, stopping stirring, putting the base cloth of which the parts are the same into the immersion tank, immersing the base cloth into the liquid, and taking out and drying the base cloth after immersing the base cloth of which the parts are the same for 10-18 minutes.
S3, forming a care layer: and (3) pouring the care solution obtained in the step (S1) and a pH regulator into an immersion liquid pool, heating to 31-35 ℃, keeping the temperature of the care solution constant, immersing the base cloth finished in the step (S2) into the care solution for 10 minutes, taking out the base cloth from the immersion liquid pool, naturally draining, and draining the redundant care solution to obtain the care layer of the adhesive bandage.
S4, fitting and splicing: and (2) laminating the PE breathable film and the ES hot-air non-woven fabric by using hot melt adhesive, pouring the prefabricated adhesive into a gluing machine, conveying the compounded PE breathable film and the ES hot-air non-woven fabric into the gluing machine, gluing one side of the ES hot-air non-woven fabric, and laminating the care layer obtained in the step S3 and the two pieces of release paper on the ES hot-air non-woven fabric in sequence.
S5, perforation molding: and (3) feeding the nursing layer and the laminating outer layer processed in the step (S4) into a perforating machine, forming micropores on the surface of the laminating outer layer, distributing the micropore rectangular arrays on two sides of a gap between the nursing layer and the laminating outer layer, perforating, sterilizing and packaging to obtain the traditional Chinese medicine type adhesive bandage with disinfection and bacteriostasis.
Preferably, the pH value of the care solution mixed with the pH regulator in the S3 is 6.8-8.8.
Preferably, the viscose prepared in the step S4 includes the following raw materials: 27-33% of guar gum, 2.8-5% of anionic surfactant, 2-4% of emulsifier and the balance of water.
Preferably, the aperture of the micropore formed on the surface of the outer layer in the bonding step S5 is 0.15-0.25 mm.
(III) advantageous effects
Compared with the prior art, the invention provides a production process of a traditional Chinese medicine type adhesive bandage with disinfection and bacteriostasis, which has the following beneficial effects:
1. the production process of the disinfection and bacteriostasis traditional Chinese medicine type adhesive bandage adopts a low-temperature mixing mode to process and treat various traditional Chinese medicine raw materials, reduces the loss of effective components in the traditional Chinese medicines on the one hand, provides guarantee for the actual efficacy of the traditional Chinese medicine, has higher product quality and utility compared with the production process of most traditional Chinese medicine type adhesive bandages on the market, reduces the energy consumption on the other hand, does not need to process by means of various precise instruments, further reduces the production and manufacturing cost of the adhesive bandage, is beneficial to popularization and use, also carries out perforation treatment on two sides of a gap between a nursing layer and an outer laminating layer of the adhesive bandage, can ensure air circulation through micropores and the gap when a user pastes the adhesive bandage on a wound, and accelerates the wound healing speed while preventing bacterial infection by matching with the disinfection and bacteriostasis utility of the adhesive bandage, the whole process is simplified in steps, and the nursing liquid preparation and nursing layer finishing methods are simple, is beneficial to mass production and use.
2. The production process of the traditional Chinese medicine type bandage with disinfection and bacteriostasis comprises the steps of adding natural traditional Chinese medicines with disinfection and bacteriostasis effects such as ethanol, plant ash, dandelion flower and the like into a nursing layer in direct contact with a wound in the bandage, reducing the possibility of bacterial infection and breeding at the wound, adding traditional Chinese medicines with hemostasis effects such as sargentgloryvine stem, dragon's blood, crinis carbonisatus and the like into the nursing layer after modification of a foaming agent, accelerating the wound healing speed, using aloe gel in the nursing layer in cooperation with a pH regulator to ensure that the pH value of the bandage added with traditional Chinese medicine components can be close to a human body, having mild and non-irritating effects when in contact with the wound, and improving the practical use experience, the adhesive used for the outer layer of the adhesive is a mixed product of natural component adhesive and active agent, has the effects of easy adhesion and easy tearing, relieves the pain of users caused by tearing the adhesive from the skin when the adhesive is replaced, and further improves the practicability.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The first embodiment is as follows:
a production process of a traditional Chinese medicine type adhesive bandage with disinfection and bacteriostasis comprises a nursing layer and an attaching outer layer, wherein the nursing layer comprises the following components in parts by weight: 150 parts of base cloth, 28 parts of sargentgloryvine stem, 23 parts of ethanol, 15 parts of aloe gel, 12 parts of houttuynia cordata, 12 parts of dragon's blood, 8 parts of Chinese angelica, 6 parts of plant ash, 5 parts of starch adhesive, 3 parts of dandelion flower, 2 parts of crinis carbonisatus and 1.4 parts of foaming agent, wherein the outer attaching layer is formed by compounding a PE (polyethylene) breathable film, ES (ethylene) hot-air non-woven fabric, release paper and adhesive, the base cloth is made of absorbent cotton, the concentration of the ethanol is 68%, and the sargentgloryvine stem, the houttuynia cordata, the Chinese angelica and the dandelion flower are all dry products after being cleaned.
The method comprises the following steps:
step one, preparation of a care solution: putting the sargentgloryvine stem, the houttuynia cordata, the dragon's blood, the angelica sinensis and the dandelion flower in corresponding parts into a wall breaking machine for crushing and mixing, wherein the rotating speed of wall breaking blades is 1200 revolutions per minute, after mixing for 10 minutes, pouring the plant ash, the starch adhesive and distilled water which is 0.4 time of the sum of the parts of the raw materials into the wall breaking machine in sequence, controlling the rotating speed of the blades of the wall breaking machine to be increased to 1600 revolutions per minute, after continuously mixing for 10 minutes, pouring out the mixed colloidal liquid from the wall breaking machine to obtain the care solution.
Step two, nursing layer finishing: pouring ethanol, aloe gel and distilled water which are 1 time of the sum of the two raw materials in parts into a liquid containing tank in sequence, heating the raw materials and the water to 35 ℃, keeping the temperature, putting the foaming agent in parts into an immersion tank, stirring and mixing at the stirring speed of 120 revolutions per minute, heating and mixing for 20 minutes, stopping stirring, putting the base cloth in parts into the immersion tank, immersing the base cloth in the liquid, soaking for 10 minutes, and taking out and drying the base cloth.
Step three, forming a nursing layer: and (3) pouring the care solution obtained in the step one and a pH regulator into an immersion liquid pool, keeping the pH value of the mixed care solution at 6.8, heating to 31 ℃, keeping the temperature of the care solution constant, immersing the base cloth finished in the step two into the care solution, taking out the base cloth from the immersion liquid pool after immersing for 10 minutes, naturally draining, and draining the redundant care solution to obtain the care layer of the adhesive bandage.
Step four, laminating and splicing: the hot melt adhesive is used for laminating the PE breathable film and the ES hot air non-woven fabric, and the adhesive comprises the following raw materials in proportion in a gluing machine for pouring the prefabricated adhesive: feeding the compounded PE breathable film and the ES hot-air non-woven fabric into a glue spreader, gluing one side of the ES hot-air non-woven fabric, and sequentially attaching the care layer obtained in the third step and two pieces of release paper to the ES hot-air non-woven fabric.
Step five, perforation molding: and (3) feeding the nursing layer and the laminating outer layer processed in the fourth step into a hole-forming machine, forming micropores on the surface of the laminating outer layer, wherein the pore diameter of each micropore is 0.15 mm, the micropores are distributed on two sides of a gap between the nursing layer and the laminating outer layer in a rectangular array manner, and sterilizing and packaging after perforation to obtain the traditional Chinese medicine type adhesive bandage with disinfection and bacteriostasis.
Example two:
a production process of a traditional Chinese medicine type adhesive bandage with disinfection and bacteriostasis comprises a nursing layer and an attaching outer layer, wherein the nursing layer comprises the following components in parts by weight: 150 parts of base cloth, 33 parts of sargentgloryvine stem, 30 parts of ethanol, 22 parts of aloe gel, 15 parts of houttuynia cordata, 15 parts of dragon's blood, 12 parts of Chinese angelica, 9 parts of plant ash, 10 parts of starch adhesive, 4 parts of dandelion flower, 2.4 parts of crinis carbonisatus and 1.6 parts of foaming agent, wherein the outer attaching layer is formed by compounding a PE (polyethylene) breathable film, an ES (ethylene-styrene-butadiene) hot-air non-woven fabric, release paper and viscose, the base cloth is made of absorbent cotton, the concentration of the ethanol is 68%, and the sargentgloryvine stem, the houttuynia cordata, the Chinese angelica and the dandelion flower are all.
The method comprises the following steps:
step one, preparation of a care solution: putting the sargentgloryvine stem, the houttuynia cordata, the dragon's blood, the angelica sinensis and the dandelion flower in corresponding parts into a wall breaking machine for crushing and mixing, wherein the rotating speed of wall breaking blades is 1300 revolutions per minute, after mixing for 10 minutes, pouring the plant ash, the starch adhesive and distilled water which is 0.5 time of the sum of the parts of the raw materials into the wall breaking machine in sequence, controlling the rotating speed of the blades of the wall breaking machine to be increased to 1750 revolutions per minute, after continuously mixing for 15 minutes, pouring out the mixed colloidal liquid from the wall breaking machine, and obtaining the care solution.
Step two, nursing layer finishing: pouring ethanol, aloe gel and distilled water which are 1 time of the sum of the two raw materials in parts into a liquid containing tank in sequence, heating the raw materials and the water to 40 ℃, keeping the temperature, putting the foaming agent in parts into an immersion tank, stirring and mixing at the stirring speed of 120 revolutions per minute, heating and mixing for 20 minutes, stopping stirring, putting the base cloth in parts into the immersion tank, immersing the base cloth in the liquid, soaking for 14 minutes, and taking out and drying the base cloth.
Step three, forming a nursing layer: and (3) pouring the care solution obtained in the step one and a pH regulator into an immersion liquid pool, keeping the pH value of the mixed care solution at 7.8, heating to 33 ℃, keeping the temperature of the care solution constant, immersing the base cloth finished in the step two into the care solution, taking out the base cloth from the immersion liquid pool after immersing for 10 minutes, naturally draining, and draining the redundant care solution to obtain the care layer of the adhesive bandage.
Step four, laminating and splicing: the hot melt adhesive is used for laminating the PE breathable film and the ES hot air non-woven fabric, and the adhesive comprises the following raw materials in proportion in a gluing machine for pouring the prefabricated adhesive: 30% of guar gum, 3.9% of anionic surfactant, 3% of emulsifier and the balance of water, feeding the compounded PE breathable film and the ES hot-air non-woven fabric into a glue spreader, spreading glue on one surface of the ES hot-air non-woven fabric, and sequentially attaching the care layer obtained in the third step and two pieces of release paper to the ES hot-air non-woven fabric.
Step five, perforation molding: and (3) feeding the nursing layer and the laminating outer layer processed in the fourth step into a hole-forming machine, forming micropores on the surface of the laminating outer layer, wherein the pore diameter of each micropore is 0.20 mm, the micropores are distributed on two sides of a gap between the nursing layer and the laminating outer layer in a rectangular array manner, and sterilizing and packaging after perforation to obtain the traditional Chinese medicine type adhesive bandage with disinfection and bacteriostasis.
Example three:
a production process of a traditional Chinese medicine type adhesive bandage with disinfection and bacteriostasis comprises a nursing layer and an attaching outer layer, wherein the nursing layer comprises the following components in parts by weight: 150 parts of base cloth, 38 parts of sargentgloryvine stem, 37 parts of ethanol, 29 parts of aloe gel, 18 parts of houttuynia cordata, 16 parts of dragon's blood, 16 parts of Chinese angelica, 12 parts of plant ash, 15 parts of starch adhesive, 5 parts of dandelion flower, 2.8 parts of crinis carbonisatus and 1.8 parts of foaming agent, wherein the outer attaching layer is formed by compounding a PE (polyethylene) breathable film, an ES (ethylene-styrene-butadiene) hot-air non-woven fabric, release paper and viscose, the base cloth is made of absorbent cotton, the concentration of the ethanol is 68%, and the sargentgloryvine stem, the houttuynia cordata, the Chinese angelica and the dandelion flower are all.
The method comprises the following steps:
step one, preparation of a care solution: putting the sargentgloryvine stem, the houttuynia cordata, the dragon's blood, the angelica sinensis and the dandelion flower in corresponding parts into a wall breaking machine for crushing and mixing, wherein the rotating speed of wall breaking blades is 1400 revolutions per minute, after mixing for 10 minutes, pouring the plant ash, the starch adhesive and distilled water which is 0.6 time of the sum of the parts of the raw materials into the wall breaking machine in sequence, controlling the rotating speed of the blades of the wall breaking machine to be increased to 1900 revolutions per minute, after continuously mixing for 20 minutes, pouring out the mixed colloidal liquid from the wall breaking machine to obtain the care solution.
Step two, nursing layer finishing: pouring ethanol, aloe gel and distilled water which are 1 time of the sum of the two raw materials in parts into a liquid containing tank in sequence, heating the raw materials and the water to 45 ℃, keeping the temperature constant, putting the foaming agent in parts into an immersion tank, stirring and mixing at the stirring speed of 120 revolutions per minute, heating and mixing for 20 minutes, stopping stirring, putting the base cloth in parts into the immersion tank, immersing the base cloth in the liquid, soaking for 18 minutes, and taking out and drying the base cloth.
Step three, forming a nursing layer: and (3) pouring the care solution obtained in the step one and a pH regulator into an immersion liquid pool, keeping the pH value of the mixed care solution at 8.8, heating to 35 ℃, keeping the temperature of the care solution constant, immersing the base cloth finished in the step two into the care solution, taking out the base cloth from the immersion liquid pool after immersing for 10 minutes, naturally draining, and draining the redundant care solution to obtain the care layer of the adhesive bandage.
Step four, laminating and splicing: the hot melt adhesive is used for laminating the PE breathable film and the ES hot air non-woven fabric, and the adhesive comprises the following raw materials in proportion in a gluing machine for pouring the prefabricated adhesive: feeding the compounded PE breathable film and the ES hot-air non-woven fabric into a glue spreader, gluing one side of the ES hot-air non-woven fabric, and sequentially attaching the care layer obtained in the step three and two pieces of release paper to the ES hot-air non-woven fabric.
Step five, perforation molding: and (3) feeding the nursing layer and the laminating outer layer processed in the fourth step into a hole-forming machine, forming micropores on the surface of the laminating outer layer, wherein the pore diameter of each micropore is 0.25 mm, the micropore rectangular arrays are distributed on two sides of the gap between the nursing layer and the laminating outer layer, and sterilizing and packaging after perforation to obtain the traditional Chinese medicine type band-aid with disinfection and bacteriostasis.
The prior wound dressings on the market are not breathable, which may cause wound suppuration and have poor use effect, the traditional Chinese medicine type wound dressings are produced by processing traditional Chinese medicine raw materials in a high-temperature mixing mode, so that the loss of active ingredients is more, the quality of finished products is further influenced, the traditional Chinese medicine ingredients are possibly more irritant, the pain of a wounded person is aggravated when the traditional Chinese medicine type wound dressings are in direct contact with wounds, the production process adopts a low-temperature mixing mode to process various traditional Chinese medicine raw materials, the loss of the active ingredients in the traditional Chinese medicines is reduced, the actual efficacy is guaranteed, the production and manufacturing cost of the wound dressings is reduced, the popularization and use of the whole steps are simplified, the nursing liquid preparation and nursing layer arrangement method is simple, the mass production and use are facilitated, the possibility of bacterial infection and breeding at the wounds is reduced, and the nursing layer is modified by a foaming agent, surface and inside are flooded with a large amount of micropores, help the circulation of air of wound and skin laminating back wound department, reduce the possibility that the wound the pustulation condition appears to a certain extent, can also accelerate wound healing speed, aloe gel has still been used on the nursing layer, the use of cooperation PH regulator, make its bandage PH value that adds after having traditional chinese medicine composition can press close to the human body, have mild non-irritating effect when contacting with the wound, and the viscose that the outer use of laminating is natural composition and active agent mixing product, the effect of easy subsides and easy tear has, it tears the painful sense of bringing down from skin to have alleviateed the user when changing the bandage, promote in-service use experience.
Claims (8)
1. A production process of a traditional Chinese medicine type adhesive bandage with disinfection and bacteriostasis is characterized in that: the nursing layer comprises the following components in parts by weight: 150 parts of base cloth, 28-38 parts of sargentgloryvine stem, 23-37 parts of ethanol, 15-29 parts of aloe gel, 12-18 parts of houttuynia cordata, 12-16 parts of dragon's blood, 8-16 parts of Chinese angelica, 6-12 parts of plant ash, 5-15 parts of starch adhesive, 3-5 parts of dandelion flower, 2-2.8 parts of carbonized hair and 1.4-1.8 parts of foaming agent.
2. The production process of the traditional Chinese medicine type wound plaster for disinfection and bacteriostasis, according to claim 1, is characterized in that: the outer layer of the joint is formed by compounding a PE breathable film, ES hot air non-woven fabric, release paper and viscose glue.
3. The production process of the traditional Chinese medicine type wound plaster for disinfection and bacteriostasis, according to claim 1, is characterized in that: the base cloth is made of absorbent cotton, and the concentration of ethanol is 68%.
4. The production process of the traditional Chinese medicine type wound plaster for disinfection and bacteriostasis, according to claim 1, is characterized in that: the sargentgloryvine stem, the houttuynia cordata, the angelica sinensis and the dandelion flowers are all dry products after being cleaned and dried.
5. The production process of the traditional Chinese medicine type wound plaster for disinfection and bacteriostasis, according to claim 1, is characterized in that: the method comprises the following steps:
s1, preparation of a care solution: putting the sargentgloryvine stem, the houttuynia cordata, the dragon's blood, the angelica sinensis and the dandelion flower in corresponding parts into a wall breaking machine for crushing and mixing, wherein the rotating speed of wall breaking blades is 1200-1400 revolutions per minute, after mixing for 10 minutes, pouring the plant ash, the starch adhesive and distilled water which is 0.4-0.6 time of the sum of the parts of the raw materials into the wall breaking machine in sequence, controlling the rotating speed of the blades of the wall breaking machine to be increased to 1600-1900 revolutions per minute, after continuously mixing for 10-20 minutes, pouring out the mixed colloidal liquid from the wall breaking machine to obtain the care solution.
S2, finishing the care layer: pouring ethanol, aloe gel and distilled water of which the parts are 1 time of the sum of the two raw materials into a liquid containing tank in sequence, heating the raw materials and the water to 35-45 ℃, keeping the temperature, putting the foaming agent of which the parts are the same into an immersion tank, stirring and mixing at the stirring speed of 120 revolutions per minute, heating and mixing for 20 minutes, stopping stirring, putting the base cloth of which the parts are the same into the immersion tank, immersing the base cloth into the liquid, and taking out and drying the base cloth after immersing the base cloth of which the parts are the same for 10-18 minutes.
S3, forming a care layer: and (3) pouring the care solution obtained in the step (S1) and a pH regulator into an immersion liquid pool, heating to 31-35 ℃, keeping the temperature of the care solution constant, immersing the base cloth finished in the step (S2) into the care solution for 10 minutes, taking out the base cloth from the immersion liquid pool, naturally draining, and draining the redundant care solution to obtain the care layer of the adhesive bandage.
S4, fitting and splicing: and (2) laminating the PE breathable film and the ES hot-air non-woven fabric by using hot melt adhesive, pouring the prefabricated adhesive into a gluing machine, conveying the compounded PE breathable film and the ES hot-air non-woven fabric into the gluing machine, gluing one side of the ES hot-air non-woven fabric, and laminating the care layer obtained in the step S3 and the two pieces of release paper on the ES hot-air non-woven fabric in sequence.
S5, perforation molding: and (3) feeding the nursing layer and the laminating outer layer processed in the step (S4) into a perforating machine, forming micropores on the surface of the laminating outer layer, distributing the micropore rectangular arrays on two sides of a gap between the nursing layer and the laminating outer layer, perforating, sterilizing and packaging to obtain the traditional Chinese medicine type adhesive bandage with disinfection and bacteriostasis.
6. The production process of the traditional Chinese medicine type wound plaster for disinfection and bacteriostasis, according to claim 5, is characterized in that: the pH value of the care solution mixed with the pH regulator in the S3 is 6.8-8.8.
7. The production process of the traditional Chinese medicine type wound plaster for disinfection and bacteriostasis, according to claim 5, is characterized in that: the prefabricated viscose glue in the S4 comprises the following raw materials in parts by weight: 27-33% of guar gum, 2.8-5% of anionic surfactant, 2-4% of emulsifier and the balance of water.
8. The production process of the traditional Chinese medicine type wound plaster for disinfection and bacteriostasis, according to claim 5, is characterized in that: the aperture of the micropore formed on the surface of the outer layer in the S5 is 0.15-0.25 mm.
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