CN112741654B - Adapted biopsy sampling and submitting device for tumor - Google Patents
Adapted biopsy sampling and submitting device for tumor Download PDFInfo
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- CN112741654B CN112741654B CN202110151433.7A CN202110151433A CN112741654B CN 112741654 B CN112741654 B CN 112741654B CN 202110151433 A CN202110151433 A CN 202110151433A CN 112741654 B CN112741654 B CN 112741654B
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- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
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Abstract
The invention discloses a matched living body sampling and submitting device for tumors, which comprises a submitting box and a sampling tank matched with the submitting box, wherein a movable inclined slide way and a horizontal slide way fixedly connected with the right end of the movable inclined slide way are arranged at the upper left part in the submitting box, a clamping device is arranged above the horizontal slide way, an air pressure pushing device is arranged at the left side of the top of the clamping device, an air bag heating device is arranged at the right side in the submitting box, a vacuum pump chamber is arranged at the bottom of the left side in the submitting box, an air pump chamber is arranged at the bottom of the right side in the submitting box, and the air bag heating device is fixedly connected with the top of the air pump chamber. The device can ensure the rapid and stable sampling process and improve the sampling efficiency and the accuracy of the sampling position; the contact between the sample and the air is reduced to the maximum extent in the process of sending the sample, the activity of the sample is maintained, and the accuracy of the detection result is ensured.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to a set of adaptive biopsy sampling and submitting devices special for tumors.
Background
The biopsy is an important method for diagnosing diseases by taking the living tissue for morphological examination. Biopsy is mainly used for the identification of tumor and non-tumor diseases, benign and malignant tumors, the judgment of the degree and range of malignant tumor growth, invasion and metastasis, the observation of the development degree or treatment response of diseases, and the like. It is the most important part of the diagnosis of pathology and a clear histopathological diagnosis can be made for the vast majority of examined cases, called the final diagnosis in the clinic.
However, most biopsy sampling devices in the prior art are complex in structure, and shaking occurs in the sampling process, so that the sampling position is deviated, the working efficiency is reduced, and the general applicability is low; meanwhile, after sampling is finished, the obtained living body sample is usually directly placed in a storage box for transportation, excessive contact exists between the sample and air in the transportation process, and the moving process shakes to a certain extent, so that the possibility that the sample is infected with harmful substances or the activity of the sample is reduced due to vibration in the transportation process is high, the probability of deviation of the final inspection result is high, and further treatment of a patient is not facilitated.
Therefore, there is a need to design a special sampling and examining device for tumor biopsy, which can simplify the sampling step, ensure the sampling efficiency, maintain the activity of the sample to the maximum extent during the examination process, ensure the accuracy of the final detection result as much as possible, and is beneficial to the rehabilitation of tumor patients.
Disclosure of Invention
Aiming at the problems, the invention aims to provide a set of adaptive biopsy sampling and submitting device for the tumor, which has the advantages of rapid and stable sampling process and improved sampling efficiency and accuracy of a sampling position; the contact between the sample and the air is reduced to the maximum extent in the process of sending the sample, the activity of the sample is maintained, and the accuracy of the detection result is ensured.
In order to achieve the purpose, the technical scheme adopted by the invention is as follows: an adaptive biopsy sampling and submitting device for tumors, which comprises a submitting box and a sampling tank matched with the submitting box, a movable inclined slideway and a horizontal slideway fixedly connected with the right end of the movable inclined slideway are arranged at the left upper part in the delivery box, a clamping device is arranged above the horizontal slideway, an air pressure pushing device is arranged on the left side of the top of the clamping device, the right side in the inspection box is provided with an air bag heating device, the bottom of the left side in the inspection box is provided with a vacuum pump chamber, the bottom of the right side in the inspection box is provided with an air pump chamber, the air bag heating device is fixedly connected with the top of the air pump chamber, a sample inlet is arranged on the left panel of the censorship box, an embedded closed panel is connected with the sample inlet through a hinge, a pull ring is arranged on the closed panel, a master control panel is arranged at the top of the right side of the left side panel to control the running of all programs in the inspection box, and a first mesh grid plate is arranged at the bottom of the left side panel and at the position corresponding to the vacuum pump chamber; be equipped with the sample connection on the right side panel of censorship case, connect embedded closed door plant at sample connection department's loose-leaf, be equipped with the pull ring on the closed door plant, the position that corresponds with the pneumatic pump room in the bottom of right side panel is equipped with netted check board two, is equipped with the sealing strip on the sample connection inner wall.
Furthermore, the middle part of the clamping device is a central column, the front end and the rear end of the bottom of the central column are respectively provided with a hinged groove, an inverted L-shaped clamping arm is hinged in each hinged groove and can rotate up and down in each hinged groove, the outer end of a cross rod of each clamping arm is respectively provided with a connecting rod which is connected with a movable ring arm on the central column, the front side and the rear side of the central column are respectively provided with a longitudinal sliding groove, the inner side of each movable ring arm is provided with a sliding block corresponding to the sliding groove, the movable ring arms can move up and down on the central column, the left side and the right side of each movable ring arm are respectively provided with a telescopic column which is connected with the bottom of a top plate at the top of the central column, an air cylinder I is arranged above the top plate to control the telescopic column to stretch, the front side and the rear side of the air cylinder I are respectively provided with a sliding block, and the bottom of the top surface of the inspection box is provided with a transverse sliding groove corresponding to the sliding block, the sliding block is matched with the sliding groove, a rotatable horizontal movable rod is embedded in a longitudinal rod of the clamping arm, a clamping block is arranged at the inner side end of the movable rod, a limiting block is arranged at the outer side end of the movable rod, a ring buckle is arranged on the clamping arm and above the limiting block, a spring is arranged between the ring buckle and the top of the limiting block, and anti-skidding strips are arranged on opposite surfaces of the two clamping blocks; the upper end of the central column is provided with a section of telescopic section, and the right side of the first cylinder is provided with a telescopic cylinder for controlling the telescopic section to stretch.
Furthermore, the air pressure pushing device comprises a second air cylinder fixedly arranged on the left side face of the inspection box and a piston rod connected between the second air cylinder and the top plate, a first spring is arranged on the outer side of the piston rod, one end of the first spring is fixedly connected with the right side face of the second air cylinder, and the other end of the first spring is fixedly connected with the left side face of the top plate.
Further, the airbag heating device comprises a constant-temperature shockproof box, a protective sponge layer is arranged on the inner wall of the constant-temperature shockproof box, a closed airbag is arranged inside the constant-temperature shockproof box, a closed cavity is formed between the closed airbag and the inner wall of the constant-temperature shockproof box, a temperature sensor is arranged in the closed cavity, the bottom of the left side of the closed cavity is connected with an air pump in an air pump chamber through an air inlet pipe, a gas heating device is arranged between the air pump and the closed cavity, and a gas discharge pipe is connected between the bottom of the right side of the closed cavity and the air pump chamber.
Furthermore, a vacuum pump is arranged in the vacuum pump chamber, the vacuum pump is communicated with the interior of the inspection box through a vacuum-pumping pipe, and an auxiliary connecting pipe is arranged on the vacuum-pumping pipe and penetrates through the first reticular grid plate to be led to the exterior of the inspection box.
Furthermore, the sampling tank comprises a tank body and a screw joint cover screwed on the top of the tank body, an auxiliary connecting interface is arranged on the side wall of the top of the tank body, the mouth part is sealed by a plug, a telescopic movable rod is arranged at the bottom of the screw joint cover, an air cylinder is arranged at the top of the screw joint cover to control the telescopic movement of the telescopic movable rod, an air cylinder switch is arranged on the top surface of the screw joint cover to control the opening of the air cylinder III, the bottom of the telescopic movable rod is connected with a sampler through a fixed rod, the specification of the sampler can be changed according to the actual condition, a through hole is arranged at the position of the bottom of the tank body corresponding to the sampler, a motor is arranged at the side edge of the through hole, the output end of the motor is connected with a rotary rod, the end part of the rotary rod is fixedly connected with the side edge of a rotary disc at the bottom of the inner side of the tank body, the diameter of the rotary disc is larger than that of the through hole, a clamping groove is respectively arranged on the left side wall and the right side wall of the tank body, and the clamping groove extends along the height direction of the tank body, be equipped with a pair of removal guide block respectively on the lateral wall around the jar body, every all contains two independent blocks to removing the guide block, the independent block extends along the direction of height of the jar body, all is equipped with a spliced eye in the bottom of every independent block, matches grafting laminating positioner in the spliced eye.
Furthermore, the laminating and positioning device comprises a connecting ring and four inserting rods which are connected to the side face of the connecting ring and correspond to the inserting holes one by one, the inserting rods are matched with the inserting holes, a movable box is connected to the inserting rods in a sliding mode, a silica gel sucker is arranged at the bottom of the movable box, and a second spring is arranged between the bottom of each inserting rod and the bottom face of the movable box.
Furtherly all is equipped with the location guide block on the bottom surface of the last lower extreme that removes the slope slide and horizontal slide, the length direction of location guide block edge slide extends, the location guide block that removes the slope slide bottom is in same direction as connecing with the location guide block driving fit on the horizontal slide, is equipped with the closed end at the right-hand member of horizontal slide, is equipped with shockproof felt pad on the inner wall of horizontal slide, the front and back end that removes the slope slide is equipped with a transmission respectively.
Further, transmission includes the lead screw of vertical setting and establishes the step motor at the lead screw top, connects a movable block respectively on the same horizontal position on the side around removing the slope slide left end, the movable block screw thread cup joints on the lead screw, the open position that avoids the slide in the left side that removes the slope slide is equipped with airtight reinforcing plate, airtight reinforcing plate is in on the same vertical plane with the left surface that removes the slope slide.
Furthermore, electric valves are arranged on the gas inlet pipe, the gas outlet pipe and the vacuum pumping pipe, and a manual valve is arranged on the auxiliary connecting pipe and is positioned outside the inspection box.
The beneficial effects of the invention are: the invention provides a set of adaptive biopsy sampling and inspecting device for tumors, which is matched with the biopsy sampling and inspecting device for use, so that the contact time of a sample and air is greatly reduced, the sample is prevented from being polluted by harmful substances in the air, and the activity of the sample is ensured; the sample moving process is stable, the damage to the sample is further reduced, and the accurate detection in the later period is facilitated; the sampling tank has a simple structure, high sampling speed and high stability, and avoids the problem of sampling position deviation caused by shaking in the sampling process; the sampler can be changed as required, and the general adaptation of equipment is stronger.
Drawings
FIG. 1 is a schematic front view of a set of adapted biopsy devices for tumors in accordance with the present invention;
FIG. 2 is a schematic left side view of a matched biopsy device for tumors in accordance with the present invention;
FIG. 3 is a schematic right-side view of a set of adapted biopsy devices for tumors in accordance with the present invention;
FIG. 4 is a schematic right side view of a grasping device of a set of adapted biopsy devices for tumors according to the present invention;
FIG. 5 is a schematic right side view of the interior of the left side panel of the delivery box of a set of adapted biopsy devices of the present invention for tumors;
FIG. 6 is a schematic front view of a sampling canister of an adapted biopsy device for tumors in accordance with the present invention;
FIG. 7 is a schematic bottom view of a sampling canister of an adapted biopsy device for tumors in accordance with the present invention;
FIG. 8 is a schematic front view of a sampling cup of a biopsy device adapted for tumor biopsy according to the present invention, after being inserted into the joint positioning device.
Wherein:
1-a checking box, 2-a sampling tank, 3-a movable inclined slideway, 4-a horizontal slideway, 5-a clamping device, 6-an air pressure pushing device, 7-an air bag heating device, 8-a vacuum pump chamber and 9-an air pump chamber;
11-a sample inlet, 12-a closed panel, 13-a master control panel, 14-a first mesh grid plate, 15-a sample inlet, 16-a closed door plate, 17-a second mesh grid plate, 18-a sealing strip;
51-center column, 52-hinge groove, 53-clamping arm, 54-connecting rod, 55-movable annular arm, 56-telescopic column, 57-top disc, 58-cylinder I and 59-sliding block;
531-a movable rod, 532-a clamping block, 533-a limiting block, 534-a buckle, 535-a spring and 536-an anti-slip strip;
61-a second cylinder, 62-a piston rod, 63-a first spring;
71-a constant temperature shockproof box, 72-a protective sponge layer, 73-a closed air bag, 74-a temperature sensor, 75-an air inlet pipe, 76-an air pump, 77-an air heating device and 78-an air outlet pipe;
81-vacuum pump, 82-vacuum tube and 83-auxiliary connecting tube;
21-tank body, 22-screw joint cover, 23-through hole, 24-motor, 25-rotary table, 26-clamping groove, 27-moving guide block, 28-plug hole and 29-joint positioning device;
221-telescopic movable rod, 222-cylinder three, 223-fixed rod, 224-sampler;
291-connecting ring, 292-inserting rod, 293-movable box, 294-silica gel sucker and 295-spring II;
31-a positioning guide block, 32-a transmission device, 33-a screw rod, 34-a stepping motor, 35-a movable block and 36-an airtight reinforcing plate;
41-closed end, 42-shockproof felt pad.
Detailed Description
In order to make those skilled in the art better understand the technical solution of the present invention, the following description will be made with reference to the accompanying drawings and embodiments.
It should be noted that the embodiment provided by the present invention is only for effectively explaining technical features of the present invention, and the positioning words such as the left side, the right side, the upper end, the lower end, etc. are only for better describing the embodiment of the present invention and should not be construed as limiting the technical solution of the present invention.
Referring to fig. 1-8, the present invention discloses an adaptive biopsy sampling device for tumor, which is used to solve the problems of complicated tumor biopsy sampling device, poor stability, sample feeding box unable to isolate air and low sample activity in the prior art, and comprises a biopsy box 1 and a sampling tank 2 used in cooperation with the biopsy box 1, wherein the cooperation of the sampling tank and the biopsy box can reduce the butt joint process of two devices to the maximum extent, the speed is high, the stability is high, the contact between the sample and the outside is reduced, and the sample activity is maintained; a movable inclined slide way 3 and a horizontal slide way 4 fixedly connected with the right end of the movable inclined slide way 3 are arranged on the upper left side in the submission box 1, a clamping device 5 is arranged above the horizontal slide way 4, an air pressure pushing device 6 is arranged on the left side of the top of the clamping device 5, an air bag heating device 7 is arranged on the right side in the submission box 1, a vacuum pump chamber 8 is arranged at the bottom of the left side in the submission box 1, an air pump chamber 9 is arranged at the bottom of the right side, and the air bag heating device 7 is fixedly connected with the top of the air pump chamber 9; a sample inlet 11 is arranged on a left side panel of the submission box 1, an embedded closed panel 12 is connected with the sample inlet 11 in a loose-leaf manner, a pull ring is arranged on the closed panel 12, a master control panel 13 is arranged at the top of the right side of the left side panel to control the running of all programs in the submission box 1, and a first mesh grid plate 14 is arranged at the bottom of the left side panel and at a position corresponding to the vacuum pump chamber 8; the right side panel of the censorship box 1 is provided with a sampling port 15, the sampling port 15 is in loose-leaf connection with an embedded type closing door panel 16, the closing door panel 16 is provided with a pull ring, the bottom of the right side panel is provided with a mesh grid plate II 17 at a position corresponding to the air pump chamber 9, and the inner wall of the sampling port 15 is provided with a sealing strip 18 for strengthening the air tightness inside the censorship box 1.
The middle part of the clamping device 5 is provided with a central column 51, the front end and the rear end of the bottom of the central column 51 are respectively provided with a hinged groove 52, the hinged grooves 52 are respectively hinged with an inverted L-shaped clamping arm 53, the clamping arms 53 can rotate up and down in the hinged grooves 52, the outer ends of the cross rods of the clamping arms 53 are respectively hinged with a connecting rod 54 and connected with a movable annular arm 55 on the central column 51, the front side and the rear side of the central column 51 are respectively provided with a longitudinal sliding groove, the inner sides of the movable annular arms 55 corresponding to the sliding grooves are respectively provided with a sliding block, the movable annular arms 55 can slide up and down on the central column 51, the left side and the right side of each movable annular arm 55 are respectively provided with a telescopic column 56 and connected with the bottom of a top disc 57 at the top of the central column 51, and a cylinder 58 is arranged above the top disc 57 to control the telescopic column 56 to stretch out and draw back; the front side and the rear side of the first air cylinder 58 are respectively provided with a sliding block 59, the bottom of the top surface of the submission box 1 is provided with a transverse sliding groove at a position corresponding to the sliding block 59, the sliding block 59 is matched with the sliding groove, a rotatable horizontal movable rod 531 is embedded in a longitudinal rod of the clamping arm 53, a clamping block 532 is arranged at the inner side end of the movable rod 531, a limiting block 533 is arranged at the outer side end of the movable rod 531, a ring buckle 534 is arranged on the clamping arm 53 and above the limiting block 533, a spring 535 is arranged between the ring buckle 534 and the top of the limiting block 533 for quick reset of the limiting block 533, and anti-slip strips 536 are arranged on opposite surfaces of the two clamping blocks 532 to enhance clamping stability; the upper end of the central column 51 is provided with a telescopic section, and the right side of the first cylinder is provided with a telescopic cylinder for controlling the telescopic section to stretch.
The pneumatic pushing device 6 comprises a second air cylinder 61 fixedly arranged on the left side face of the inspection box 1 and a piston rod 62 connected between the second air cylinder 61 and the top plate 57, a first spring 63 is arranged on the outer side of the piston rod 62, one end of the first spring 63 is fixedly connected with the right side face of the second air cylinder 61, and the other end of the first spring is fixedly connected with the left side face of the top plate 57.
The airbag heating device 7 comprises a constant-temperature shockproof box 71, a protective sponge layer 72 is arranged on the inner wall of the constant-temperature shockproof box 71, a closed airbag 73 is arranged inside the constant-temperature shockproof box 71, a closed cavity is formed between the closed airbag 73 and the inner wall of the constant-temperature shockproof box 71, a temperature sensor 74 is arranged in the closed cavity, the bottom of the left side of the closed cavity is connected with an air pump 76 in an air pump chamber 9 through an air inlet pipe 75, an air heating device 77 is arranged between the air pump 76 and the closed cavity, and an air outlet pipe 78 is connected between the bottom of the right side of the closed cavity and the air pump chamber 9.
A vacuum pump 81 is arranged in the vacuum pump chamber 8, the vacuum pump 81 is communicated with the interior of the examination box 1 through a vacuum tube 82, and an auxiliary connecting tube 83 is arranged on the vacuum tube 82 and penetrates through the first mesh grid plate 14 to lead to the exterior of the examination box 1.
The sampling tank 2 comprises a tank body 21 and a screw joint cover 22 screwed on the top of the tank body 21, the tank body 21 is made of stainless steel materials, an auxiliary connecting interface is arranged on the side wall of the top of the tank body 21 and is butted with an auxiliary connecting pipe 83, the mouth part is sealed by a plug, a telescopic movable rod 221 is arranged at the bottom of the screw joint cover 22, a cylinder three 222 is arranged at the top of the screw joint cover 22 and controls the telescopic movable rod 221 to stretch, a cylinder switch is arranged on the top surface of the screw joint cover 22 and controls the cylinder three 222 to open, a sampler 224 is connected at the bottom of the telescopic movable rod 221 through a fixed rod 223, the specification of the sampler 224 can be changed according to actual conditions, the universality of the equipment is enhanced, a through hole 23 is arranged at the position corresponding to the sampler 224 at the bottom of the tank body 21, a motor 24 is arranged at the side edge of the through hole 23, the output end of the motor 24 is connected with a rotary rod, and the end of the rotary rod is fixedly connected with the side edge of a rotary disc 25 at the bottom inside the tank body 21, the diameter of the rotary table 25 is larger than that of the through hole 23, a clamping groove 26 is respectively arranged on the left side wall and the right side wall of the tank body 21, the clamping groove 26 extends along the height direction of the tank body 21, the clamping block 532 can be inserted into the clamping groove 26, a pair of moving guide blocks 27 is respectively arranged on the front side wall and the rear side wall of the tank body 21, each pair of moving guide blocks 27 comprises two independent blocks, each independent block extends along the height direction of the tank body 21, a plugging hole 28 is arranged at the bottom of each independent block, and a plugging and jointing positioning device 29 is matched and plugged in the plugging hole 28.
The upper end and the lower end of the movable inclined slideway 3 and the bottom surface of the horizontal slideway 4 are provided with positioning guide blocks 31, the positioning guide block 31 extends along the length direction of the slide way, the positioning guide block 31 at the bottom end of the movable inclined slide way 3 is closely and sequentially connected with the positioning guide block 31 on the horizontal slide way 4, so that the sampling tank 2 can smoothly slide to the horizontal slide way 4 from the movable inclined slide way 3 and keep the tank body 21 from rotating, the clamping grooves 26 are always positioned at the front side and the rear side after sliding to the horizontal slide way 4, and the subsequent clamping operation of the clamping device 5 is convenient, the right end of the horizontal slideway 4 is provided with a closed end 41 to prevent the sampling tank 2 from rushing out of the slideway, the inner wall of the horizontal slideway 4 is provided with a shockproof felt pad 42 for reducing the impact force when the sampling tank 2 moves onto the horizontal slideway 4 and contacts with the closed end 41, and the front end and the rear end of the movable inclined slideway 3 are respectively provided with a transmission device 32.
The transmission 32 includes the lead screw 33 of vertical setting and establishes the step motor 34 at lead screw 33 top, connects a movable block 35 respectively on the same horizontal position of the preceding of 3 left ends of removal slope slide, trailing flank, movable block 35 threaded sleeve connects can accomplish on lead screw 33 and reciprocate along with the rotation of lead screw 33 after starting step motor 34 on the lead screw 33, and the open position of avoiding the slide in the left side of removing slope slide 3 is equipped with airtight reinforcing plate 36, airtight reinforcing plate 36 is in on the same vertical plane with the left surface that removes slope slide 3.
Electric valves are arranged on the gas inlet pipe 75, the gas outlet pipe 78 and the vacuum pipe 82, and a manual valve is arranged on the auxiliary connecting pipe 83, and the manual valve is positioned outside the inspection box 1.
The invention discloses a biopsy sampling and submitting device, which comprises the following specific operation steps:
first, sampling
Firstly, the motor 24 is started to enable the turntable 25 to cover the through hole 23, so that a relatively closed space is formed inside the tank body 21, the auxiliary connecting port is in butt joint with the auxiliary connecting pipe 83, the vacuum pump 81 is started through the main control panel 13, the manual valve on the auxiliary connecting pipe 83 is manually opened to vacuumize the inside of the tank body 21 to reduce the contact probability of the sample and air after sampling as much as possible, the vacuum pump 81 is closed after the manual valve is closed after vacuumizing is finished, and the auxiliary connecting port is plugged by a plug for sealing.
Then, the attaching and positioning device 29 is inserted into the insertion hole 28 at the bottom of the movable guide block 27, the silica gel suction cup 29 at the bottom of the attaching and positioning device 29 is tightly attached to the surface of a human body, sampling position deviation caused by shaking of equipment in the sampling process is avoided, then the motor 24 is started again to enable the position of the rotary disc 25 to be staggered with that of the through hole 23, the telescopic movable rod 221 moves to a focus position under the action of the cylinder three 222 for sampling, the tank body 21 is quickly retracted after sampling is finished, the rotary disc 25 seals the through hole 23, and finally the attaching and positioning device 29 is taken down for subsequent inspection.
Second, submission
Before storing samples, firstly opening the sealing panel 12, taking down a plug on the auxiliary connecting interface to ensure that the tank body 21 is not completely sealed so as to be beneficial to follow-up secondary vacuum pumping, plugging two pairs of movable guide blocks on the tank body 21 into the movable inclined slide ways 3 at positions corresponding to the positioning guide blocks 31, quickly closing the sealing panel 12, downwards moving the tank body 21 to the horizontal slide ways 4 under the action of gravity, and starting a vacuum pump 81 and an electric valve on a vacuum pumping pipe 82 to pump the interior of the inspection box 1 and the interior of the tank body 21 to be vacuum;
starting the first cylinder 58 to enable the telescopic column 56 to relax downwards to drive the movable ring arm 55 to move downwards, finally pressing the clamping arm 53 downwards to enable the clamping blocks 532 on the clamping arm 53 to be correspondingly inserted into the clamping grooves 26 on the front side surface and the rear side surface of the tank body 21, then starting the stepping motor 34 to enable the movable block 35 to move downwards on the screw rod 33, and further sealing the position of the sample inlet 11 by the airtight reinforcing plate 36 in the moving process to reinforce the air tightness inside the inspection box 1;
after the inclined slide way 3 and the horizontal slide way 4 are moved to descend, the sampling tank 2 clamped by the clamping block 532 rotates under the action of gravity, the tank body 21 is changed from a horizontal state to a vertical state, the sampling tank 2 is placed into the constant-temperature shockproof box 71 in a follow-up manner, then the cylinder II 61 is started to enable the piston rod 62 to relax to drive the clamping device 5 to move rightwards, the clamping device 5 stops moving when moving to the position right above the constant-temperature shockproof box 71, the telescopic cylinder is started to drive the telescopic section to relax downwards, when the lower half part of the sampling tank 2 falls into the constant-temperature shockproof box 71 and the clamping arm 53 is still positioned outside the constant-temperature shockproof box 71, the cylinder I58 is started to enable the telescopic column 56 to contract to cause the clamping arm 53 to rotate and open, and as most of the sampling tank 2 at the moment falls into the constant-temperature shockproof box 71 and the protective sponge layer 72 and the closed air bag 73 have good buffering effect, when the rest part of the sampling tank 2 falls, large impact can not be received, the design can ensure the falling stability of the sampling tank 2 and is beneficial to the loosening of the clamping arm 53;
can make the sample keep higher activity when the temperature of sample in censorship case 1 is close to its temperature in the human body, therefore, can be according to the data of temperature sensor 74 transmission, utilize gas heater 77 to heat the gas in the closed cavity, make sample temperature invariable, open closed door plant 16 and take out sample tank 2 when transporting censorship department, whole censorship in-process sample is few with the contact process of air, can avoid the harmful substance pollution sample in the air, it is steady to transport the process simultaneously, avoid the sample damage, guarantee the sample activity, improve and detect the rate of accuracy, be of value to the correct diagnosis of patient's disease.
The foregoing shows and describes the general principles, principal features and advantages of the invention. However, the above description is only an example of the present invention, and the technical features of the present invention are not limited thereto, and other embodiments that can be made by those skilled in the art without departing from the technical scope of the present invention should be covered by the claims of the present invention.
Claims (7)
1. The adaptive biopsy sampling and submitting device for the tumor is characterized by comprising a biopsy box (1) and a sampling tank (2) matched with the biopsy box (1) for use, wherein a movable inclined slide way (3) and a horizontal slide way (4) fixedly connected with the right end of the movable inclined slide way (3) are arranged at the upper left side in the biopsy box (1), a clamping device (5) is arranged above the horizontal slide way (4), an air pressure pushing device (6) is arranged at the left side of the top of the clamping device (5), an air bag heating device (7) is arranged at the right side in the biopsy box (1), a vacuum pump chamber (8) is arranged at the bottom of the left side in the biopsy box (1), an air pump chamber (9) is arranged at the bottom of the right side, and the air bag heating device (7) is fixedly connected with the top of the air pump chamber (9); a sample inlet (11) is arranged on a left side panel of the submission box (1), an embedded type closed panel (12) is connected with the sample inlet (11) through a hinge, a pull ring is arranged on the closed panel (12), a master control panel (13) is arranged at the top of the right side of the left side panel, and a first mesh grid plate (14) is arranged at the bottom of the left side panel and corresponds to the vacuum pump chamber (8); a sampling port (15) is arranged on the right side panel of the submission box (1), an embedded type closing door panel (16) is connected with the sampling port (15) through hinges, a pull ring is arranged on the closing door panel (16), a second net-shaped grid plate (17) is arranged at the bottom of the right side panel and corresponds to the air pump chamber (9), and a sealing strip (18) is arranged on the inner wall of the sampling port (15);
the air bag heating device (7) comprises a constant-temperature shockproof box (71), a protective sponge layer (72) is arranged on the inner wall of the constant-temperature shockproof box (71), a closed air bag (73) is arranged inside the constant-temperature shockproof box (71), a closed cavity is formed between the closed air bag (73) and the inner wall of the constant-temperature shockproof box (71), a temperature sensor (74) is arranged in the closed cavity, the bottom of the left side of the closed cavity is connected with an air pump (76) in an air pump chamber (9) through an air inlet pipe (75), an air heating device (77) is arranged between the air pump (76) and the closed cavity, and an air outlet pipe (78) is connected between the bottom of the right side of the closed cavity and the air pump chamber (9);
a vacuum pump (81) is arranged in the vacuum pump chamber (8), the vacuum pump (81) is communicated with the interior of the inspection box (1) through a vacuum tube (82), and an auxiliary connecting tube (83) is arranged on the vacuum tube (82) and penetrates through the first mesh grid plate (14) to lead to the exterior of the inspection box (1);
the sampling tank (2) comprises a tank body (21) and a screw connection cover (22) screwed on the top of the tank body (21), an auxiliary connection interface is arranged on the side wall of the top of the tank body (21), the mouth of the tank body is sealed by a plug, a telescopic movable rod (221) is arranged at the bottom of the screw connection cover (22), a third cylinder (222) is arranged at the top of the screw connection cover (22), a cylinder switch is arranged on the top surface of the screw connection cover (22), the bottom of the telescopic movable rod (221) is connected with a sampler (224) through a fixed rod (223), a through hole (23) is arranged at the position, corresponding to the sampler (224), of the bottom of the tank body (21), a motor (24) is arranged at the side edge of the through hole (23), the output end of the motor (24) is connected with a rotary rod, the end part of the rotary rod is fixedly connected with the side edge of a rotary plate (25) at the inner bottom of the tank body (21), the diameter of the rotary plate (25) is larger than that of the through hole (23), and the left side edge of the tank body (21), The right side wall is provided with a clamping groove (26), the clamping groove (26) extends along the height direction of the tank body (21), the front side wall and the rear side wall of the tank body (21) are provided with a pair of movable guide blocks (27), each pair of movable guide blocks (27) comprises two independent blocks, each independent block extends along the height direction of the tank body (21), the bottom of each independent block is provided with an inserting hole (28), and the inserting holes (28) are matched with inserting, splicing and laminating positioning devices (29).
2. The adaptive biopsy taking and examining device for tumor according to claim 1, wherein the grasping device (5) comprises a central column (51) at the middle, a hinge slot (52) is provided at the front and rear ends of the bottom of the central column (51), an inverted L-shaped grasping arm (53) is hinged in the hinge slot (52), the grasping arm (53) can rotate up and down in the hinge slot (52), a connecting rod (54) is provided at the outer end of the cross rod of the grasping arm (53) and connected with the movable ring arm (55) on the central column (51), a longitudinal sliding slot is provided on the front and rear side of the central column (51), a sliding block is provided at the position corresponding to the sliding slot inside the movable ring arm (55), the movable ring arm (55) can slide up and down on the central column (51), and a left sliding block, a right sliding block, a left sliding block and a right sliding block on the movable ring arm (55), A telescopic column (56) is arranged on each of the right two sides of the central column (51), the telescopic column is connected with the bottom of a top disc (57) at the top of the central column (51), and a first air cylinder (58) is arranged above the top disc (57) to control the telescopic column (56) to stretch; the front side and the rear side of the first cylinder (58) are respectively provided with a sliding block (59), a transverse sliding groove is formed in the position, corresponding to the sliding block (59), of the bottom of the top surface of the inspection box (1), the sliding block (59) is matched with the sliding groove, a rotatable horizontal movable rod (531) is embedded in a longitudinal rod of the clamping arm (53), clamping blocks (532) are arranged at the inner side ends of the movable rods (531), a limiting block (533) is arranged at the outer side end of the movable rod (531), a ring buckle (534) is arranged on the clamping arm (53) and above the limiting block (533), a spring (535) is arranged between the ring buckle (534) and the top of the limiting block (533), and anti-skidding strips (536) are arranged on the opposite surfaces of the two clamping blocks (532).
3. A biopsy device adapted for tumor biopsy according to claim 2, wherein the pneumatic pushing device (6) comprises a second cylinder (61) fixedly arranged on the left side surface of the biopsy box (1) and a piston rod (62) connecting the second cylinder (61) and the top plate (57), a first spring (63) is arranged outside the piston rod (62), one end of the first spring (63) is fixedly connected with the right side surface of the second cylinder (61), and the other end of the first spring is fixedly connected with the left side surface of the top plate (57).
4. The adapted biopsy sampling and inspection device for tumors of claim 3, wherein the attaching and positioning device (29) comprises a connection ring (291) and four insertion rods (292) connected to the side surface of the connection ring (291) and corresponding to the insertion holes (28) in a one-to-one manner, the insertion rods (292) are adapted to the insertion holes (28), the insertion rods (292) are slidably connected with the movable box (293), the bottom of the movable box (293) is provided with a silica gel sucker (294), and a second spring (295) is arranged between the bottom of the insertion rods (292) and the bottom surface of the movable box (293).
5. The adapted biopsy sampling and inspecting device for tumor according to claim 4, wherein the upper and lower ends of the movable inclined slideway (3) and the bottom surface of the horizontal slideway (4) are respectively provided with a positioning guide block (31), the positioning guide blocks (31) extend along the length direction of the slideway, the positioning guide blocks (31) at the bottom end of the movable inclined slideway (3) are closely and sequentially connected with the positioning guide blocks (31) on the horizontal slideway (4), the right end of the horizontal slideway (4) is provided with a closed end (41), the inner wall of the horizontal slideway (4) is provided with a shockproof felt pad (42), and the front and rear ends of the movable inclined slideway (3) are respectively provided with a transmission device (32).
6. The adapted biopsy device for tumor according to claim 5, wherein the transmission device (32) comprises a vertically arranged screw rod (33) and a stepping motor (34) arranged on the top of the screw rod (33), a movable block (35) is respectively connected to the front side and the rear side of the left end of the movable inclined slideway (3) at the same horizontal position, the movable block (35) is sleeved on the screw rod (33) in a threaded manner, an airtight reinforcing plate (36) is arranged at the left side of the movable inclined slideway (3) to avoid the opening position of the slideway, and the airtight reinforcing plate (36) and the left side of the movable inclined slideway (3) are on the same vertical plane.
7. A biopsy device adapted for use in tumor biopsy according to claim 6, wherein electric valves are provided on the gas inlet tube (75), the gas outlet tube (78) and the evacuation tube (82), and a manual valve is provided on the auxiliary connection tube (83), said manual valve being located outside the biopsy chamber (1).
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