CN112717113A

CN112717113A - Traditional Chinese medicine composition for treating allergic rhinitis and ointment formula and application thereof

Info

Publication number: CN112717113A
Application number: CN202110134404.XA
Authority: CN
Inventors: 吴�灿; 陈慧珍; 邓行行
Original assignee: Qionghai Hospital Of Traditional Chinese Medicine
Current assignee: Qionghai Hospital Of Traditional Chinese Medicine
Priority date: 2021-01-29
Filing date: 2021-01-29
Publication date: 2021-04-30
Anticipated expiration: 2041-01-29
Also published as: CN112717113B

Abstract

The invention provides a traditional Chinese medicine composition for treating allergic rhinitis, a paste formula and an application thereof, wherein the traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 9-12 parts of white paeony root, 15-25 parts of pinellia tuber, 10-15 parts of dried ginger, 9-15 parts of cassia twig, 15-20 parts of ephedra herb, 10-15 parts of Chinese magnoliavine fruit, 3-6 parts of asarum, 9-12 parts of fried bitter apricot seed, 9-12 parts of honey-fried licorice root, 50-80 parts of astragalus root, 10-15 parts of divaricate saposhnikovia root, 20-30 parts of Chinese yam, 15-20 parts of dogwood, 15-25 parts of prepared rehmannia root, 10-15 parts of oriental waterplantain rhizome, 3-6 parts of black cis piece, 9-12 parts of tree, 10-15 parts of angelica sinensis, 10-15 parts of rhizoma atractylodis, 6-12 parts of dried orange peel, 10-15 parts of poria cocos, 9-15 parts of red ginseng, 60-90 parts of Chinese date, 6-10 parts of cocklebur fruit, 12-16 parts of radix angelicae, 9-12 parts of biond magnolia flower, 3-6 parts of deer-horn gelatin and 3-6 parts of fructus evodiae. The traditional Chinese medicine composition is suitable for preparing a paste formula, has good taking taste and high patient compliance, and can be used for treating the patients with the deficient and cold allergic rhinitis, so that the traditional Chinese medicine composition is quick in effect taking and high in safety, can improve the immunity and the physique, and fundamentally improves the disease prevention capability.

Description

Traditional Chinese medicine composition for treating allergic rhinitis and ointment formula and application thereof

Technical Field

The invention relates to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating allergic rhinitis, a formula of an ointment of the traditional Chinese medicine composition and application of the traditional Chinese medicine composition.

Background

In recent years, with the progress of urbanization, the air quality in some areas is reduced, and the incidence of Allergic Rhinitis (AR) is on the rise. The symptoms are mainly manifested by paroxysmal sneeze, nasal secretion increase, nasal obstruction, nasal itching, nasal mucosa swelling, etc. The disease can occur in any age group, is easy to repeatedly attack, and seriously affects the life and work of patients. The influence is more obvious in children and teenagers, and the influence affects normal sleeping and learning, even affects the growth and development of children, and brings great inconvenience to life and learning of the children. And the children patients have the characteristic of poor compliance compared with the adults patients. According to clinical tests, the total effective rate of the loratadine for treating allergic rhinitis is about 80%, but the cure rate is less than 10%. The cure rate of the existing traditional Chinese medicine ointment formula for treating allergic rhinitis is improved, but is only about 20 percent. Moreover, the traditional Chinese medicine formula for treating allergic rhinitis only aims at treating allergic rhinitis and does not aim at physical characteristics, so that the traditional Chinese medicine formula can be used for fundamentally improving the physical quality, improving the immunity and preventing diseases.

Disclosure of Invention

In view of the above, the invention provides a traditional Chinese medicine composition for treating allergic rhinitis, which is suitable for preparing a paste formula and has good taste when being taken, and aims at patients with deficiency and cold, so that the traditional Chinese medicine composition can effectively treat allergic rhinitis, improve immunity and improve physique, and fundamentally improve the disease prevention capability.

The technical scheme of the invention is realized as follows:

a traditional Chinese medicine composition for treating allergic rhinitis is prepared from the following raw material medicines in parts by weight: 9-12 parts of white paeony root, 15-25 parts of pinellia tuber, 10-15 parts of dried ginger, 9-15 parts of cassia twig, 15-20 parts of ephedra herb, 10-15 parts of Chinese magnoliavine fruit, 3-6 parts of asarum, 9-12 parts of fried bitter apricot seed, 9-12 parts of honey-fried licorice root, 50-80 parts of astragalus root, 10-15 parts of divaricate saposhnikovia root, 20-30 parts of Chinese yam, 15-20 parts of dogwood, 15-25 parts of prepared rehmannia root, 10-15 parts of oriental waterplantain rhizome, 3-6 parts of black cis piece, 9-12 parts of tree, 10-15 parts of angelica sinensis, 10-15 parts of rhizoma atractylodis, 6-12 parts of dried orange peel, 10-15 parts of poria cocos, 9-15 parts of red ginseng, 60-90 parts of Chinese date, 6-10 parts of cocklebur fruit, 12-16 parts of radix angelicae, 9-12 parts of biond magnolia flower, 3-6 parts of deer-horn gelatin and 3-6 parts of fructus evodiae.

Preferably, the traditional Chinese medicine composition for treating allergic rhinitis is prepared from the following raw material medicines in parts by weight:

9 parts of white paeony root, 15 parts of pinellia ternate, 10 parts of dried ginger, 9 parts of cassia twig, 15 parts of ephedra, 15 parts of Chinese magnoliavine fruit, 6 parts of asarum, 9 parts of fried bitter apricot seed, 9 parts of honey-fried licorice root, 50 parts of astragalus mongholicus, 10 parts of divaricate saposhnikovia root, 20 parts of Chinese yam, 15 parts of dogwood, 15 parts of prepared rehmannia root, 10 parts of rhizoma alismatis, 3 parts of black shun slices, 9 parts of tree peony bark, 10 parts of Chinese angelica, 10 parts of rhizoma atractylodis, 6 parts of dried orange peel, 10 parts of poria cocos, 9 parts of red ginseng, 60 parts of Chinese date, 10 parts of cocklebur fruit.

Further, the traditional Chinese medicine composition also comprises the following raw material medicines in parts by weight: 30-40 parts of ginger, 6-12 parts of cinnamon, 6-10 parts of raw liquorice, 3-6 parts of caulis clematidis armandii, 10-15 parts of mint, 10-15 parts of dark plum, 9-12 parts of starwort root, 6-9 parts of ligusticum wallichii, 30-45 parts of radix puerariae, 30-45 parts of gypsum, 9-12 parts of radix bupleuri, 5-9 parts of scutellaria baicalensis, 10-15 parts of scorched hawthorn fruit, 10-15 parts of scorched malt, 10-15 parts of scorched medicated leaven and 10-15 parts of stevia rebaudiana.

Preferably, the traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: the traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 9-10 parts of white paeony root, 15-17 parts of pinellia tuber, 10-12 parts of dried ginger, 9-10 parts of cassia twig, 15-17 parts of ephedra herb, 13-15 parts of Chinese magnoliavine fruit, 5-6 parts of asarum, 9-10 parts of fried bitter apricot seed, 9-0 part of honey-fried licorice root, 50-55 parts of astragalus root, 10-12 parts of divaricate saposhnikovia root, 6-8 parts of dried orange peel, 10-12 parts of poria cocos, 30-35 parts of ginger, 10-12 parts of rhizoma atractylodis, 9-10 parts of red ginseng, 60-65 parts of Chinese date, 9-8 parts of moutan bark, 6-8 parts of cinnamon, 20-23 parts of Chinese yam, 15-18 parts of dogwood, 15-18 parts of prepared rehmannia root, 10-12 parts of rhizoma alismatis, 3-4 parts of black cis slices, 10-12 parts of angelica, 9-10 parts, 9-10 parts of cocklebur fruit, 13-15 parts of mint, 13-15 parts of dark plum fruit, 9-10 parts of starwort root, 6-7 parts of ligusticum wallichii, 3-4 parts of deerhorn glue, 12-13 parts of angelica dahurica, 9-10 parts of biond magnolia flower, 30-35 parts of kudzuvine root, 30-35 parts of gypsum, 9-10 parts of radix bupleuri, 5-6 parts of scutellaria baicalensis, 10-12 parts of scorched hawthorn fruit, 10-12 parts of scorched malt, 10-12 parts of scorched medicated leaven and 10-12 parts of stevia rebaudiana.

More preferably, the traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: the traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 9 parts of white paeony root, 15 parts of pinellia tuber, 10 parts of dried ginger, 9 parts of cassia twig, 15 parts of ephedra, 15 parts of Chinese magnoliavine fruit, 6 parts of asarum, 9 parts of fried bitter apricot seed, 9 parts of honey-fried licorice root, 50 parts of astragalus root, 10 parts of divaricate saposhnikovia root, 6 parts of dried orange peel, 10 parts of poria cocos, 30 parts of ginger, 10 parts of rhizoma atractylodis, 9 parts of red ginseng, 60 parts of Chinese date, 9 parts of tree peony bark, 6 parts of cinnamon, 20 parts of Chinese yam, 15 parts of dogwood, 15 parts of prepared rehmannia root, 10 parts of oriental waterplantain rhizome, 3 parts of black cis, 10 parts of Chinese angelica, 10 parts of raw licorice, 3 parts of clematis stem, 6 parts of evodia rutaecarpa fruit, 10 parts of cocklebur fruit, 15 parts of mint, 15 parts of dark plum fruit, 9 parts of starwort root, 6 parts of szechuan lovage rhizome, 3 parts of deerhorn glue, 12.

A traditional Chinese medicine composition ointment formula for treating allergic rhinitis is prepared from any one of the traditional Chinese medicine compositions.

A preparation method of a traditional Chinese medicine composition ointment for treating allergic rhinitis comprises the following steps: the preparation method comprises the steps of taking the raw materials according to the parts by weight, pouring the raw materials into preparation equipment of a traditional Chinese medicine room paste formula, adding water and yellow wine, decocting with strong fire until the pot is boiled, adjusting to slow fire, continuously stirring, decocting for 0.8-1.2 hours, adding maltose, collecting paste, bottling, airing the paste, and sealing to obtain the paste formula.

The application of the traditional Chinese medicine composition for treating allergic rhinitis in preparation of a medicine for treating allergic rhinitis is disclosed in any one of the invention.

In the formula, the ephedra herb and the cassia twig are sweaty and cold-dispelling to relieve exterior pathogens, the ephedra herb can also disperse lung qi to relieve asthma and cough, and the cassia twig can transform qi and promote diuresis to benefit interior fluid; huang Qi is sweet and warm, and can tonify qi of spleen and lung internally, strengthen superficies to check sweating; the red ginseng is sweet and warm, and has the effects of tonifying qi, strengthening spleen and nourishing stomach; yam, rhizoma Dioscoreae, fructus Corni, fructus Schisandrae chinensis, and radix Paeoniae alba are used as principal drugs for invigorating spleen and replenishing qi, invigorating spleen and lung, nourishing yin and blood, and regulating menstruation. The dried ginger and the asarum herb warm the lung and resolve retention of fluid, and also assist the ephedra herb and the cassia twig to relieve exterior syndrome and eliminate pathogenic factors; rhizoma Atractylodis strengthens spleen and qi, and helps radix astragali to strengthen qi-tonifying and exterior-consolidating effects; angelica and evodia rutaecarpa, warming meridians, nourishing blood and dispelling cold; the HEISHUAN tablet has effects of dispelling cold and tonifying yang, and colla Cornus Cervi has effects of warming and invigorating liver and kidney, replenishing vital essence and nourishing blood, and is used as ministerial drug. Pericarpium Citri Tangerinae and rhizoma Pinelliae have the effects of promoting qi circulation, eliminating dampness, eliminating phlegm, regulating stomach function, and lowering adverse qi; the radix sileris is pungent and warm in property and releases exterior to dissipate wind evil, the astragalus and the rhizoma atractylodis are combined to tonify qi and eliminate evil, the astragalus can be used for strengthening exterior without retaining evil, the radix sileris can be used for eliminating evil without damaging vital qi, and the radix sileris has the effect of strengthening middle-jiao and dispersing, and strengthening middle-jiao and dispersing; poria strengthens the spleen and eliminates dampness, and Poria cocos and rhizoma atractylodis are matched to strengthen the spleen and eliminate dampness; fructus Xanthii is suitable for relieving stuffy nose, dispelling pathogenic wind and relieving pain, flos Magnoliae and herba Menthae are suitable for relieving stuffy nose, and radix Angelicae Dahuricae is suitable for dispelling pathogenic wind and treating lung; dark plum is sour and astringent, and can resolve yin and promote the production of body fluid; the schisandra chinensis is sour, sweet and warm, and has the effects of tonifying qi, astringing lung, tonifying kidney and nourishing yin; parched semen Armeniacae amarum has effects of relieving cough and asthma, cortex moutan has effects of promoting blood circulation and removing blood stasis, and Alismatis rhizoma has effects of promoting diuresis and eliminating dampness, and can be used as adjuvant drugs. Prepared licorice root, radix Glycyrrhizae Praeparata has the effects of invigorating qi, regulating the middle warmer, and harmonizing the effects of the other drugs; ginger also serves as a guiding drug, and helps pinellia ternate to harmonize the stomach, and Chinese date helps red ginseng and honey-fried licorice root to tonify qi, so that the combination of the raw materials can also regulate ying and wei, and the raw materials together serve as a guiding drug. The compatibility of the medicines is strict, the medicines are folded when being scattered, and the medicines are folded when being opened, so that the symptoms are balanced when wind-cold is relieved, water is removed, and the wind-cold is diffused and descended.

Furthermore, radix bupleuri clears the pathogenic factors of shaoyang half exterior, relieves the pathogenic factors from the outside, and cortex Cinnamomi dispels cold and invigorates yang, and is combined with the monarch drugs to be a monarch drug; the ginger warms the channel, nourishes blood and dissipates cold, and is combined with the ministerial drugs to serve as a ministerial drug; radix Stellariae, radix bupleuri, radix Puerariae, radix Scutellariae, radix bupleuri, radix Puerariae, rhizoma Chuanxiong, radix Puerariae, Gypsum Fibrosum, radix Scutellariae. The scorched hawthorn fruit, the scorched malt and the scorched medicated leaven help digestion and prevent the stomach from being obstructed by greasy taste; stevia rebaudiana has sweet taste and mild nature, corrects the taste, and is combined with the guiding drugs for tonifying qi and regulating the middle warmer. Further enhancing the curative effect and optimizing the taste.

Compared with the prior art, the invention has the beneficial effects that:

(1) the traditional Chinese medicine composition has strict compatibility, can be collected in powder, can be combined in opening, can relieve wind-cold, can remove water retention, and can relieve the symptoms. Is suitable for treating allergic rhinitis for patients with deficiency and cold.

(2) Clinical verification shows that the traditional Chinese medicine composition has quick response and no wound, has good taste and high patient compliance when being used for treating allergic rhinitis, and effectively solves the problem of poor compliance of children patients when being taken. Furthermore, the traditional Chinese medicine composition is particularly suitable for being prepared into a paste formula, the prepared paste formula is convenient to take and has better taste, and the taking compliance of patients is further improved.

(3) The traditional Chinese medicine composition can relieve the pain of allergic rhinitis for patients, improve immunity, improve physique, fundamentally improve the prevention capability of diseases, save treatment cost, is green and safe, and can be clinically popularized.

Detailed Description

In order to better understand the technical content of the invention, specific examples are provided below to further illustrate the invention.

The experimental methods used in the examples of the present invention are all conventional methods unless otherwise specified.

The materials, reagents and the like used in the examples of the present invention can be obtained commercially without specific description.

First, the basic conditions of the main raw material drugs of the invention

[01] White peony root, radix Paeoniae alba, bitter and sour in taste and slightly cold in nature, enters liver and spleen channels, and has the effects of nourishing blood, regulating menstruation, astringing yin, arresting sweating, softening liver, relieving pain and calming liver yang. It is commonly used for blood deficiency and chlorosis, irregular menstruation, spontaneous perspiration, night sweat, hypochondriac pain, abdominal pain, limb spasm and pain, headache and vertigo.

[02] Pinellia ternata has the function of lowering adverse qi and relieving vomiting, and is used for treating excessive phlegm, cough and asthma, phlegm and fluid, dizziness and palpitation, wind-phlegm dizziness, phlegm syncope, headache, vomiting and regurgitation, fullness and stuffiness in chest and epigastrium and globus hystericus; unprocessed for treating abscess and phlegm nodule.

[03] Zingiberis rhizoma has effects of warming spleen and stomach for dispelling cold, restoring yang and dredging collaterals, and warming lung to eliminate retained fluid. The decoction and volatile oil of dried ginger have obvious antithrombotic and platelet aggregation resisting functions, and the ether extract and ethanol extract of dried ginger have obvious anti-inflammatory functions.

[04] Gui Zhi, pungent and sweet with warm property enters heart, lung and bladder meridians. Has effects of inducing sweat, expelling pathogenic factors from muscles, warming and dredging channels, supporting yang, regulating qi, and lowering qi. It is commonly used for wind-cold type common cold, abdominal cold pain, amenorrhea due to blood cold, arthralgia, phlegm and fluid retention, edema and palpitation. Gui Zhi is pungent in flavor and warm in property and can move yin and move blood, so it is indicated for exogenous febrile disease, hyperactivity of fire due to yin deficiency, recklessly blood flow due to blood heat, etc.

[05] The ephedra herb is warm in nature, pungent and slightly bitter in taste, has the effects of sweating, dispelling cold, ventilating and smoothing lung, relieving asthma, inducing diuresis and reducing edema through lung channel and bladder channel, and can treat cold due to wind-cold, chest distress, cough and asthma, edema, bronchial asthma and other diseases. It is contraindicated or cautiously used for treating mild syndrome of wind-cold, palpitation, insomnia, cough and asthma due to lung deficiency, and prohibited for spontaneous sweating due to physical deficiency, night sweat, dyspnea due to deficiency and yang hyperactivity due to yin deficiency. Ephedrine is adrenomimetic drug. Can excite sympathetic nerve, and has longer drug effect than epinephrine; can relax bronchial smooth muscle and contract blood vessel; has obvious central excitation effect. The traditional Chinese medicine composition is mainly used for treating habitual bronchial asthma and preventing asthma attack in clinic. The treatment effect on severe bronchial asthma is not as good as that of epinephrine, but when the medicine is used for nasal mucosa congestion and nasal obstruction, the treatment effect is better than that of epinephrine.

[06] The schisandra chinensis is sour and sweet in taste and warm in nature, enters lung, heart and kidney channels, has the effects of astringing, arresting discharge, tonifying qi, promoting the production of body fluid, tonifying kidney and calming heart, and is used for treating chronic cough, deficiency asthma, nocturnal emission, enuresis, frequent micturition, chronic diarrhea, spontaneous perspiration, night sweat, body fluid consumption, thirst, internal heat, thirst, palpitation and insomnia. The main active ingredients of the medicine are lignans such as deoxyschizandrin, schisandrin B, schisandrin A, schisandrin B and the like, and the medicine also contains a plurality of volatile oils such as pinene and the like and organic acid compounds such as citric acid, malic acid, tartaric acid and the like, and has obvious enzyme reduction effect on the serum glutamic-pyruvic transaminase of hepatitis B patients. The mechanism is that the synthesis of enzyme by liver cells is inhibited, the liver cell has no obvious effect on normal liver, and the activity of the enzyme is inhibited more for injured liver.

[07] The asarum is pungent, warm and low in toxicity, and has the effects of invigorating heart, lung and kidney channels, relieving exterior syndrome, dispelling cold, dispelling wind, relieving pain, dredging orifices, warming lung and resolving fluid retention, and can be used for treating wind-cold type common cold, headache, toothache, rheumatic arthralgia, nasosinusitis and cough due to lung cold. It is contraindicated for headache due to yin deficiency and yang hyperactivity, and dry cough due to lung dryness.

[08] The fried bitter almond has the effects of descending qi, relieving cough and asthma and relaxing bowel, is used for treating cough and asthma, fullness in chest and excessive phlegm, blood deficiency and fluid depletion, and constipation due to intestinal dryness, contains amygdalin, and the amygdalin can be hydrolyzed by intestinal microbial enzyme or amygdalin contained in the bitter almond in vivo to generate trace hydrocyanic acid and benzaldehyde, has the inhibiting effect on respiratory center, and achieves the effects of relieving cough and asthma. The almond kernel is rich in fatty oil which can improve the lubricating effect of intestinal contents on mucous membranes, so that the almond kernel has the function of relaxing bowels. Amygdalin is decomposed by enzyme to form hydrocyanic acid, and simultaneously, benzaldehyde is generated, which can inhibit the activity of pepsin, thereby affecting the digestion function.

[09] The liquorice has the effects of tonifying spleen and qi, clearing heat and detoxicating, eliminating phlegm and stopping cough, relieving spasm and pain and harmonizing the drugs, is used for treating weakness of the spleen and the stomach, lassitude and hypodynamia, palpitation and shortness of breath, cough and profuse sputum, abdominal distension and spasm pain of limbs, carbuncle and sore toxicity, and relieving toxicity and severity of the drugs, mainly contains saponin, flavonoid, polysaccharide, coumarin, quercetin and trace elements, wherein the saponin comprises glycyrrhizic acid and glycyrrhetinic acid, the flavonoid comprises liquiritin, isoliquiritin and liquiritigenin, the liquorice water extract has obvious anti-inflammatory effect, and the liquiritin and the glycyrrhizic acid have obvious anti-allergic effect.

[10] Astragalus root, sweet in taste, slightly warm in nature, enter spleen and lung channels, have the efficacy of invigorating qi, consolidating superficial resistance, expelling toxin, expelling pus, promoting urination and promoting tissue regeneration, are used for qi deficiency and hypodynamia, chronic diarrhea and rectocele, spontaneous perspiration, edema, uterine prolapse, chronic nephritis proteinuria, diabetes and unhealed sore mouth, mainly contain several components such as saponin, flavone, polysaccharide and amino acid, etc., astragalus polysaccharide has the function of reducing blood fat, namely reducing cholesterol and triglyceride and increasing high-density lipoprotein; can be used for preventing and treating cardiovascular and cerebrovascular diseases, such as atherosclerosis, coronary artery disease, peripheral angiopathy, and hyperlipidemia. Astragaloside IV has effects of remarkably reducing blood sugar, glycosylated hemoglobin and urine protein, and reducing AGEs in renal cortex and blood serum, and has effects of resisting oxidation, inhibiting aldose reductase, inhibiting mesangial cell proliferation, and relieving renal hypertrophy.

[11] Radix Saposhnikoviae, pungent and sweet in flavor, slightly warm in nature, enters bladder, liver, spleen and liver meridians, has effects of dispelling pathogenic wind, relieving exterior syndrome, eliminating dampness, relieving pain, and relieving spasm, and can be used for treating exterior syndrome due to exogenous pathogenic factor, rubella pruritus, rheumatalgia, tetanus, spleen deficiency, and excessive dampness.

[12] The dried orange peel is bitter and pungent in taste and warm in nature, enters lung and spleen channels, has the effects of regulating qi, tonifying spleen, eliminating dampness and reducing phlegm, is used for treating abdominal distension, anorexia, vomiting and diarrhea and cough with excessive phlegm, mainly contains flavonoids, alkaloids, limonoids, volatile oils, trace elements and other components, and has wide pharmacological effects of boosting pressure, resisting arteriosclerosis, soothing liver and benefiting gallbladder, resisting allergy, resisting tumors, resisting oxidation, resisting bacteria and the like.

[13] Poria cocos is sweet and light in taste, has a neutral nature, enters heart, lung, spleen and kidney channels, has the effects of promoting diuresis, excreting dampness, invigorating spleen and calming heart, and is used for treating edema oliguria, phlegm and fluid retention, dizziness and palpitation, spleen deficiency and poor appetite, loose stool and diarrhea, uneasiness, palpitation and insomnia. The sclerotium of Poria cocos contains beta-pachyman 93 wt% and triterpenes such as acetylpachymic acid, pachymic acid, and 3 beta-hydroxy lanostane trienoic acid. In addition, the medicine also contains gum, chitin, protein, fat, sterol, lecithin, glucose, adenine, histidine, choline, beta-pachyman lyase, lipase and protease, and can be injected into rabbit abdominal cavity with alcohol extract or used in rabbit chronic experiment with water extract, and has diuretic effect.

[14] The ginger is pungent in taste and slightly warm in nature, enters lung, spleen and stomach channels, has the effects of relieving exterior syndrome, dispelling cold, warming middle energizer, arresting vomiting, warming lung, relieving cough and detoxifying, can be used for treating cold due to wind-cold, spleen and stomach cold, stomach cold vomiting, lung cold cough and detoxifying, mainly contains the components of gingerol, zingiberene, bisabolene, alpha-curcumene, linalool, eucalyptol, alpha-borneol, gingerol, decomposition products of zingerone, various amino acids and the like, has the effects of invigorating stomach, resisting gastric ulcer, benefiting gallbladder, protecting liver, strengthening heart, inhibiting platelet aggregation, preventing dizziness, resisting tumors, inhibiting centrum, resisting bacteria, killing insects and diminishing inflammation and also has strong antioxidant capacity.

[15] Rhizoma atractylodis, pungent and bitter in taste and warm in nature, enters spleen, stomach and liver channels, has the effects of eliminating dampness and strengthening spleen, dispelling wind and cold and improving eyesight, and can be used for treating damp obstruction of middle-jiao, abdominal distention, diarrhea, edema, beriberi flaccidity cramped, rheumatic arthralgia, wind-cold type common cold, night blindness, dim eyesight and acerbity.

[16] The red ginseng has the effects of reinforcing primordial qi, recovering pulse, relieving depletion, benefiting qi and controlling blood, is mainly used for treating the symptoms of weak body, depletion, pulse cold, slight pulse, qi failure to control blood, metrorrhagia, metrostaxis and the like, contains triterpenoid saponin as a main component, volatile oil, polysaccharide, amino acid, trace elements, polypeptide and the like, and triterpenoid saponin and polysaccharide of the red ginseng are main pharmacological active components of the red ginseng.

[17] The jujube is sweet in taste and warm in nature, has the effects of tonifying qi and spleen, nourishing blood and soothing nerves and nourishing, can be used for debilitation and loose stool, and is hysteria of women, contains various vitamin components such as vitamin C, riboflavin, thiamine, carotene, nicotinic acid and the like, cyclic adenosine monophosphate contained in the jujube is an essential component for energy metabolism of human cells, can enhance muscle strength, eliminate fatigue, dilate blood vessels, increase myocardial contractility and improve myocardial nutrition, and has a good effect on prevention and treatment.

[18] Cortex moutan, bitter and pungent, slightly cold, enters heart, liver and kidney meridians, has the effects of clearing heat and cooling blood, and promoting blood circulation to remove blood stasis, and can be used for heat entering nutrient-blood, warm toxicity and macula, hematemesis and epistaxis, night fever and early coolness, no sweat and bone steaming, amenorrhea and dysmenorrhea, traumatic injury and carbuncle swelling and sore toxicity.

[19] Cinnamon is the dry bark of cinnamon belonging to the family Lauraceae, has the efficacies of supplementing fire and supporting yang, guiding fire to the origin, dispelling cold and relieving pain, and warming and dredging channels and collaterals, and is used for impotence and cold womb, cold pain in waist and knees, asthma due to kidney deficiency, floating of deficient yang, dizziness and conjunctival congestion, cold pain in heart and abdomen, vomiting and diarrhea due to deficiency cold, abdominal pain due to cold hernia, dysmenorrheal and amenorrhea and the like.

[20] The yam is a dioscorea plant of dioscoreaceae, has sweet taste and neutral nature, has mild effects on spleen channels, lung channels and kidney channels, does not have cold or dryness, invigorates qi but does not cause stagnation, nourishes yin but does not cause greasiness, and tonifies triple warmer, has the effects of tonifying middle-jiao and qi, invigorating spleen to arrest diarrhea, promoting fluid production and benefiting lung, and is used for treating weakness of spleen and stomach, tiredness, diarrhea, lung deficiency and cough, consumptive disease and cough, thirst and the like.

[21] Dogwood, dry and mature pulp of Dogwood of Cornaceae, with sour and astringent taste and mild nature, enters liver and kidney meridians, has the effects of tonifying liver and kidney, astringing and relieving depletion, and is commonly used for vertigo, tinnitus, soreness and pain of waist and knees, impotence, spermatorrhea, enuresis, frequent micturition, metrorrhagia, leukorrhagia, profuse sweat, depletion, internal heat and thirst quenching.

[22] Radix rehmanniae Preparata, the rhizome of Scrophulariaceae plant rehmanniae or Huaiqing rehmanniae, is sweet in taste and warm in nature, enters liver and kidney channels, has the effects of nourishing yin and supplementing blood, and replenishing vital essence and marrow, and can be used for treating yin deficiency and blood deficiency, waist and knee atrophy, fatigue, cough, bone steaming, spermatorrhea, metrorrhagia, irregular menstruation, thirst, scanty urine, deafness and dizziness.

[23] Alismatis rhizoma is a perennial aquatic or marsh herb, has sweet and cold taste, enters kidney and bladder channels, has effects of promoting diuresis, eliminating dampness, and clearing heat, and can be used for treating dysuresia, edema, distention, emesis, dysentery, phlegm retention, loempe, gonorrhea, hematuria, etc.

[24] The black shun tablet is a processed product of aconite, is a processed product of the root of the common monkshood daughter root of the ranunculaceae plant aconite, has pungent and sweet taste and great heat, is in the heart, kidney and spleen channels, has the effects of restoring yang, rescuing from collapse, tonifying fire, supporting yang, dispelling cold and relieving pain, and can be used for treating yang exhaustion and collapse, cold limbs and slight pulse, insufficient heart yang, chest stuffiness and pain, deficiency cold vomiting and diarrhea, abdominal cold pain, kidney yang deficiency and weakness, impotence and cold womb, yin cold edema, yang deficiency and exogenous cold-dampness arthralgia.

[25] The angelica is a dry root of angelica sinensis of an umbelliferae plant, is sweet and pungent in taste and warm in nature, enters liver, heart and spleen channels, has the effects of enriching blood and activating blood, regulating menstruation and relieving pain and relaxing bowel, and is used for treating blood deficiency and chlorosis, dizziness and palpitation, irregular menstruation, amenorrhea and dysmenorrheal, deficiency cold and abdominal pain, rheumatic arthralgia, traumatic injury, intestinal dryness and constipation and the like.

[26] Fructus Xanthii, dry mature fruit with involucre of Xanthium strumarium of Compositae, is bitter, sweet, pungent and warm in nature, enters lung and liver meridians, has effects of dispelling pathogenic wind and cold, dredging nasal orifice, dispelling pathogenic wind and dampness, and relieving pain, and can be used for treating wind-cold type common cold, nasosinusitis, rheumatalgia, rubella pruritus, etc., headache due to blood deficiency is not suitable for administration, and poisoning is easily caused by overdose administration.

[27] Herba Menthae is whole herb or leaf of herba Menthae of Labiatae, has pungent taste and cool nature, enters lung and liver channels, has effects of dispelling pathogenic wind heat, clearing head and eyes, relieving sore throat, promoting eruption, dispersing stagnated liver qi, and activating qi-flowing, and can be used for treating wind heat common cold, headache, sore throat, food stagnation and flatulence, aphtha, toothache, scabies, urticaria, epidemic febrile disease, rubella pruritus, stagnation of qi due to liver depression, chest distress and hypochondriac pain, etc.

[28] The scutellaria baicalensis is a dry root of scutellaria baicalensis of Labiatae, is bitter in taste and cold in nature, enters the channels of the lung, the gallbladder, the spleen, the large intestine and the small intestine, has the effects of clearing heat and drying dampness, purging fire and removing toxicity, stopping bleeding and preventing miscarriage, and can be used for treating damp warmth, summer dampness, chest distress and nausea, damp heat and fullness, diarrhea, jaundice, lung heat cough, high fever polydipsia, blood heat hematemesis and epistaxis, carbuncle swelling and sore toxicity, threatened abortion and the like.

[29] Dark plum, a dry nearly mature fruit of prunus mume, a rosaceous plant, is sour, astringent and neutral in nature, enters liver, spleen, lung and large intestine channels, has the effects of astringing lung, astringing intestine, promoting fluid production and calming roundworms, and can be used for treating lung deficiency chronic cough, chronic diarrhea and chronic dysentery, deficiency heat thirst, colic vomiting and abdominal pain, and the like.

[30] Radix Stellariae, the root of Stellaria dichotoma of Caryophyllaceae, is sweet and bitter, is cool, enters liver and stomach channels, has the effects of reducing deficiency heat, clearing heat and cooling blood, and clearing liver heat, and can be used for consumptive disease, bone steaming, yin deficiency, chronic malaria, infantile malnutrition, emaciation, skin fatigue, and the like.

[31] Rhizoma Ligustici Chuanxiong, pungent in flavor, warm in nature, enters liver and gallbladder meridians, has effects of promoting blood circulation, activating qi-flowing, dispelling pathogenic wind and relieving pain, and can be used for treating menoxenia, dysmenorrhea, amenorrhea, dystocia, retained afterbirth, puerperal lochiorrhea, abdominal pain, lump, pain in chest, hypochondrium, traumatic injury, swelling and pain, headache, dizziness, dim eyesight, arthralgia due to wind-cold-dampness, numbness of limbs, superficial infection, pyocutaneous disease, etc.

[32] The antler glue has sweet, salty and warm taste, belongs to liver and kidney channels, has the effects of warming and nourishing liver and kidney, replenishing vital essence and nourishing blood, and can be used for treating kidney yang weakness, blood deficiency dizziness, waist and knee soreness and coldness, essence and blood deficiency, consumptive disease emaciation and the like.

[33] Radix Angelicae Dahuricae, is an umbelliferae plant of Umbelliferae, is pungent and warm in taste, enters lung, spleen and stomach channels, has effects of dispelling pathogenic wind, eliminating dampness, subsiding swelling, relieving pain, and opening nasal orifices, and can be used for treating headache, glabellar bone pain, toothache, nasosinusitis, cold-dampness abdominal pain, intestinal wind, hemorrhoid, red and white leukorrhagia, superficial infection, pyocutaneous disease, skin pruritus, and scabies.

[34] Flos Magnoliae, a dry flower bud of Magnoliaceae plants such as flos Magnoliae, flos Magnoliae or WUDANYULAN, is pungent and warm in taste, enters lung and stomach channels, has effects of dispelling pathogenic wind and cold, and relieving nasal obstruction, and can be used for treating common cold due to wind-cold, nasal obstruction, nasosinusitis, etc.

[35] Gypsum, which is a dihydrate of calcium sulfate, is pungent, sweet and slightly cold in flavor, enters lung and stomach channels, has the effects of clearing heat and purging fire, relieving restlessness and quenching thirst, and can be used for treating stroke cold and heat, relieving muscle and sweating, eliminating dry mouth and tongue scorched, relieving headache and toothache and the like.

[36] Radix bupleuri, a perennial herb of the genus bupleurum of the family umbelliferae, is bitter and cool in taste, enters heart, liver and spleen channels, has the effects of relieving exterior syndrome, reducing fever, soothing liver, relieving depression and lifting yang qi, and can be used for treating exogenous fever, alternating chills and fever, malaria, hypochondriac pain and distension, headache, dizziness, irregular menstruation, rectocele due to sinking of qi, uterine prolapse, gastroptosis and the like.

[37] Evodia rutaecarpa, dry and nearly mature fruit of rutaecarpa, rockfoil herb or hairy evodia rutaecarpa of Rutaceae, is pungent, bitter and hot in taste, enters liver, spleen, stomach and kidney channels, has the effects of dispelling cold and relieving pain, calming adverse-rising energy and arresting vomiting, and supporting yang and stopping diarrhea, and can be used for treating jueyin headache, cold hernia and abdominal pain, cold-damp beriberi, abdominal pain during menstruation, abdominal distending pain, vomiting and acid regurgitation, morning diarrhea and the like.

[38] Pueraria lobata (Willd.) Ohwi or Pueraria thomsonii Benth, which is a dried root of Pueraria lobata (Willd.) Ohwi or Pueraria thomsonii Benth. Sweet, pungent and cool in nature and taste. It enters spleen and stomach meridians. The functions are mainly used for relieving muscles and allaying fever, promoting the production of body fluid, promoting eruption, invigorating yang and stopping diarrhea. Can be used for treating fever, headache, stiffness and pain of neck and back, thirst, diabetes, measles without adequate eruption, dysentery, and diarrhea; hypertension neck and neck pain.

[39] Caulis Clematidis Armandii is dry stem of Clematis armandi Franch or Clematis montana Buch-ham of Ranunculaceae. Bland, bitter and cold in nature and taste. Meridian tropism includes heart, lung, small intestine and bladder meridians. The functions are mainly used for clearing heat and promoting urination, and stimulating the menstrual flow and promoting lactation. Can be used for treating edema, gonorrhea, urinary obstruction, arthralgia, and amenorrhea and hypogalactia.

[40] Charred fructus crataegi, which is the dried mature fruit of fructus crataegi. Haw is sour, sweet and slightly warm in nature and taste. It enters spleen, stomach and liver meridians. The functions are mainly to promote digestion, invigorate the stomach, promote qi circulation and remove blood stasis. Can be used for treating meat food stagnation, gastric cavity distention, dysentery abdominal pain, blood stasis amenorrhea, puerperal blood stasis, heart and abdomen stabbing pain, and hernia pain; hyperlipidemia. Charring the hawthorn: and (4) putting the clean hawthorn slices into a pot, and frying until the surface is brown and the interior is yellow brown. The product has brownish brown surface and yellowish brown interior. Fragrant smell, sour and slightly astringent taste. The charred fructus crataegi has effects of resolving food stagnation. Can be used for treating food stagnation and diarrhea and dysentery.

[41] Charred malt, malt being sweet in nature and taste and mild in nature. The meridian entered spleen and stomach. The functions are mainly to promote qi circulation and digestion, invigorate spleen and stimulate appetite, and remove milk and relieve distension. Can be used for treating dyspepsia, abdominal pain, spleen deficiency, anorexia, breast pain, and female hypogalactia. Charred malt: parching clean fructus Hordei Germinatus to brown, cooling, and sieving to remove dust. Charred malt is mainly used for promoting digestion and resolving stagnation. Can be used for treating dyspepsia, abdominal distention and pain.

[42] The charred medicated leaven, medicated leaven warm in nature, enters spleen and stomach channels, and has the effects of promoting digestion, relieving stasis, invigorating spleen and regulating stomach. The charred medicated leaven is prepared by putting medicated leaven blocks into a hot pot, heating with slow fire, and continuously stir-frying until the surface turns brown and the stir-fried charred medicated leaven is fragrant. Charred Shen Qu is good at tonifying spleen and promoting appetite.

[43] Stevia rebaudiana Bertoni is the leaf of stevia rebaudiana Bertoni of Compositae. Sweet in taste and neutral in nature; the function is mainly used for promoting the production of body fluid and quenching thirst; reducing blood pressure. Diabetes mainly; hypertension.

The traditional Chinese medicine raw material in the embodiment of the invention is granules of Beijing kang Renteng pharmaceutical Co.

Preparation of Chinese medicinal ointment

EXAMPLE 1 Chinese medicinal composition

The formula is as follows: 9g of white peony root, 15g of ginger processed pinellia tuber, 10g of dried ginger, 9g of cassia twig, 15g of ephedra herb, 15g of Chinese magnoliavine fruit, 6g of asarum, 9g of fried bitter apricot seed, 9g of honey-fried licorice root, 50g of astragalus root, 10g of divaricate saposhnikovia root, 20g of Chinese yam, 15g of dogwood, 15g of prepared rehmannia root, 10g of oriental waterplantain rhizome, 3g of black shun slice, 9g of tree peony bark, 10g of Chinese angelica, 10g of rhizoma atractylodis, 6g of dried orange peel, 10g of poria cocos, 9g of red ginseng, 60g of Chinese date, 10g of cocklebur fruit.

EXAMPLE 2 Chinese medicinal composition

The formula is as follows: 12g of white peony root, 25g of ginger processed pinellia tuber, 15g of dried ginger, 15g of cassia twig, 20g of ephedra herb, 10g of Chinese magnoliavine fruit, 3g of asarum, 12g of fried bitter apricot seed, 12g of honey-fried licorice root, 80g of astragalus root, 15g of divaricate saposhnikovia root, 30g of Chinese yam, 20g of dogwood, 25g of prepared rehmannia root, 15g of oriental waterplantain rhizome, 6g of black shun slice, 12g of tree peony bark, 10g of Chinese angelica, 15g of rhizoma atractylodis, 12g of dried orange peel, 15g of poria cocos, 15g of red ginseng, 90g of Chinese date, 6g of cocklebur.

Example 3 Chinese medicinal composition

The formula is as follows: 9g of white peony root, 15g of ginger processed pinellia tuber, 10g of dried ginger, 9g of cassia twig, 15g of ephedra herb, 15g of Chinese magnoliavine fruit, 6g of asarum herb, 9g of fried bitter apricot seed, 9g of honey-fried licorice root, 50g of astragalus root, 10g of divaricate saposhnikovia root, 6g of dried orange peel, 10g of poria cocos, 30g of ginger, 10g of rhizoma atractylodis, 9g of red ginseng, 60g of Chinese date, 9g of tree peony bark, 6g of cinnamon, 20g of Chinese yam, 15g of dogwood, 15g of prepared rehmannia root, 10g of oriental waterplantain rhizome, 3g of black cis, 10g of angelica, 10g of raw licorice, 3g of clematis stem, 6g of evodia rutaecarpa fruit, 10g of siberian peppermint, 15g of dark plum fruit, 9g of starwort root, 6g of szechuan lovage rhizome, 3g of deerhorn glue, 12g of dahurian.

The preparation methods of the paste formulas in the above examples 1-3 are the same, and specifically comprise the following steps: taking the traditional Chinese medicine component granules according to the formula, pouring the granules into a container of a traditional Chinese medicine room paste formula preparation machine, adding a proper amount of drinking water and 100mL of yellow wine, decocting with strong fire until the pot is opened, adjusting to slow fire and continuously stirring, decocting for 1 hour, adding 100 g of maltose and 200g of rice wine to obtain paste, bottling, airing the paste, and sealing to obtain the paste formula.

Third, clinical application

1 clinical data

1.1 general data

The study establishes diagnosis standards and curative effect evaluation standards according to the traditional Chinese medicine disease diagnosis and curative effect standard of the State administration of traditional Chinese medicine, and the cases meeting the inclusion standards are randomly divided into study groups 1-2 and control groups of 60 cases respectively according to the treatment sequence (the center for treating disease before treatment of traditional Chinese medicine institute in Johnhai).

1.2 clinical manifestations

The symptoms are as follows: the main symptoms are sneeze, watery nasal discharge, nasal itching and nasal obstruction, the 4 symptoms exist at the same time for 2 or more, the symptoms exist continuously every day or the cumulative time reaches 1 hour, and the eye symptoms such as eye itching, lacrimation, red eyes and the like can appear at the same time;

② secondary symptoms: aversion to cold, susceptibility to wind, spontaneous perspiration, fatigue, or speech discomfort, cough, and expectoration;

③ pulse of tongue: a pale or reddish tongue with thin and white coating and a weak or floating pulse. Infants younger than 3 years of age may present with a red and superficial fingerprint.

1.3 clinical diagnostic criteria

(1) Standard of Western diagnosis

The method is mainly based on the diagnosis basis in the 'allergic rhinitis diagnosis and treatment guideline' published in 2015 in China:

the symptoms are as follows: the main symptoms are sneezing, watery nasal discharge, nasal itching and nasal obstruction, and the 4 symptoms exist simultaneously

When the number of the eye drops is 2 or more, the symptoms exist continuously or the cumulative time reaches 1 hour, and meanwhile, the eye symptoms such as itching, tearing, redness and the like can appear;

② history of diseases: the prior history of relevant allergic diseases or allergen contact history;

③ physical signs: edema, pallor and swollen nasal turbinate of nasal mucosa, there may be watery secretion in the nasal cavity;

fourthly, allergen detection: there were at least 1 allergen positive test result or serum specific Ig E positive.

(2) The traditional Chinese medicine diagnosis standard is mainly drawn to the traditional Chinese medicine syndrome differentiation standard of lung qi deficiency cold syndrome in ' traditional Chinese medicine pediatric clinical diagnosis and treatment guide ' and infantile allergic rhinitis ' published in 2016 in China:

the main symptoms are: itching, sneezing, clear or turbid nasal discharge, and nasal obstruction of 2 or more; the nasal mucosa is reddish or pale, the inferior turbinate is swollen, and watery secretion can be seen in the nasal cavity;

The selected cases are diagnosed by combining the traditional Chinese medicine diagnosis standard and the Western medicine diagnosis standard.

2 method and course of treatment

Study group 1 corresponds to taking the traditional Chinese medicine ointment formula in example 1, study group 2 corresponds to taking the traditional Chinese medicine ointment formula in example 3, each time one week of medicine is prescribed, 4 weeks are 1 course of treatment, and the total treatment time is 1 course of treatment. It is taken once a day with a spoon (about 15g) of warm water. The control group should take loratadine tablet 10mg 1 tablet each time, 1 time daily for 4 weeks.

3 Observation items and criteria for evaluating therapeutic effects

(1) The main symptoms and nasal signs setting and scoring refer to the allergic rhinitis diagnosis and treatment guideline published in 2015, and the secondary symptoms setting and scoring standard refer to the traditional Chinese medicine pediatric clinical diagnosis and treatment guideline published in 2016. The following are specifically drawn up:

score criteria for chief complaints (see table below)

TABLE 1 hierarchical quantitative scores table for chief complaints

Note: Δ number of nasal wipes per day; a consecutive number of times.

② Chinese medicine accompanied symptom scoring standard (see the following table)

TABLE 2 Chinese medicine accompanying disease grading and quantitative scoring table

③ Standard for Scoring physical signs and symptoms (see the following table)

TABLE 3 hierarchical quantitative scoring table for nasal turbinate physical signs

Recording four main symptoms of running nose, sneezing, rhinocnesmus, nasal obstruction, lung qi deficiency and cold, intolerance of cold, spontaneous perspiration, fatigue, cough, local turbinate sign fraction and recurrence interval time before and after drug treatment of the testee, the annual attack time and the 1-year recurrence time, and analyzing the following index fractions in total:

1) the rate of reduction of the integral of the syndrome in TCM (major symptoms, concurrent symptoms and signs in TCM);

2) rate of reduction of concomitant disease score in traditional Chinese medicine;

3) assessment of efficacy (major symptoms and signs).

4) The 1 year of follow-up visit, relapse was recorded.

(2) Disease efficacy evaluation criteria

The scoring method and standard of symptom and sign are drawn up as follows according to the diagnosis and treatment principle and recommendation scheme of allergic rhinitis published in Lanzhou in 2004:

and (3) evaluating the curative effect: (chief complaint + total integral of signs before treatment-chief complaint + total integral of signs after treatment)/(chief complaint + total integral of signs before treatment) × 100%

And (4) invalidation: less than or equal to 25 percent

The method has the following advantages: more than 25% and less than 66%

And (3) healing: not less than 66 percent.

4 therapeutic results

As shown in the following table, compared with a control group, statistics shows that the ointment formula has a remarkable effect of treating allergic rhinitis, the cure rate is improved to 58.3%, and the total effective rate is 98.3%. In the case of treatment observation, no adverse reaction is found.

5 typical cases

The patient is a certain woman in age of 8 years and 27.8kg, and the student makes a preliminary visit on 7 months and 10 days in 2019. The main complaints are: repeated nasal itching, nasal obstruction and nasal discharge occur for 5 years, and the recurrence is more than half a year. Patients are weak and sick by self, the patients almost catch a cold and cough every month when reading kindergarten, the sneezing and watery nasal discharge are difficult to heal after each cold, the nasal obstruction and the nasal tinnitus are generated at night, even the mouth is opened for breathing, the allergic rhinitis is confirmed by the special diagnosis and treatment, the western medicines of cetirizine drop, loratadine granules and the like are used for treating, the medicine taking is effective, but the attack is caused when the medicine is stopped, and the diagnosis is carried out by introduction. The following symptoms are shown: in recent half a year, sneezing and watery nasal discharge are repeated in the early period, occasionally cough, nasal obstruction and borborygmus at night, mouth opening and breathing, snore, dribbling sweat, heavy head sweat at night, thirst and no water drinking, no abdominal pain, anorexia, unformed stool, frequent micturition, pale and swollen tongue, diseased coating and deep pulse. After the traditional Chinese medicine ointment formula disclosed in the embodiment 1 of the invention is taken for 1 treatment course, sneezing and nasal discharge are obviously reduced, nasal obstruction and snore are greatly reduced at night, the appetite is improved, and the weight is increased. The medicine ointment formula is taken again for 21 days 12 and 12 in 2019 for 1 treatment course, no recurrence occurs in half a year after follow-up visit, and no attack occurs in 2020 in winter.

The patient is a certain one, male, 10 years old, student, and the date of first visit is 2019, 6 months and 21 days. Chief complaints are repeated sneezing and nasal discharge for more than 3 years, and aggravated by more than 5 months. The patient has repeated sneezing and snivel 3 years ago, the allergic rhinitis is diagnosed specially in the department of ophthalmology and otorhinolaryngology, the disease condition is improved after the patient gets up in the morning or is even sneezed when the patient is cooled, and the patient is diagnosed by introduction of friends. The current medical history: nearly every 5 months, the patient gets out of bed and then sneezes and has clear nasal discharge, frequent nasal obstruction at night, nasal itching, no cough, no thirst, normal sweating, poor appetite, slight sleep, thin stool, normal urine, pale red tongue, thin white fur and deep and weak pulse. After the traditional Chinese medicine is taken for 1 treatment course in the embodiment 2 of the invention, the physical exercise is strengthened, sneezing and nasal discharge are avoided, the physical fitness is improved, the disease does not recur in half a year after follow-up, and no obvious attack is found in 2020 in winter.

The patient is a new one, male, 13 years old, high student, and the initial diagnosis date is 2019, 12 months and 14 days. The patient complains about repeated sneezing and nasal discharge for more than 10 years, and the recurrence is more than 3 months. The patient repeatedly sneezes and rhinorrhoea from children, symptoms occur after cold or cooling, sneezes and continues even when the patient meets cold in the early stage, allergy to mites, fish and shrimps is considered in the process of detecting allergen, allergic rhinitis is diagnosed in the department of ophthalmology and otorhinolaryngology, and the patient is treated by Chinese and western medicines once, but the disease condition is diagnosed repeatedly through introduction. The current medical history: in nearly 3 months, the stress of learning is high, the patient feels bitter and reading when staying up all night, and in addition, the patient is careless to regulate the pressure, the patient is aggravated, nasal obstruction influences the sleep at night, sneezing and continuous early, watery nasal discharge is clear, the nose is itchy, the eyes are itchy, even cough is caused, the mouth is not dry and bitter, the sweat is easy to appear, the stomach is general, the sleep is poor, the stool is slightly thin, the urine is normal, the tongue is light and tender, the thin white fur is thin, the root is greasy, and the. After the traditional Chinese medicine ointment formula in the embodiment 3 of the invention is taken for 1 treatment course, sneezing and nasal discharge are avoided, the itching of the nose and eyes are obviously improved, the physique is obviously improved, no relapse occurs in the following half year, no obvious attack occurs in winter in 2020, sneezing is occasionally caused, and the warmth can be relieved by paying attention to the warmth retention.

The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.

Claims

1. The traditional Chinese medicine composition for treating allergic rhinitis is characterized by being prepared from the following raw material medicines in parts by weight: 9-12 parts of white paeony root, 15-25 parts of pinellia tuber, 10-15 parts of dried ginger, 9-15 parts of cassia twig, 15-20 parts of ephedra herb, 10-15 parts of Chinese magnoliavine fruit, 3-6 parts of asarum, 9-12 parts of fried bitter apricot seed, 9-12 parts of honey-fried licorice root, 50-80 parts of astragalus root, 10-15 parts of divaricate saposhnikovia root, 20-30 parts of Chinese yam, 15-20 parts of dogwood, 15-25 parts of prepared rehmannia root, 10-15 parts of oriental waterplantain rhizome, 3-6 parts of black cis piece, 9-12 parts of tree, 10-15 parts of angelica sinensis, 10-15 parts of rhizoma atractylodis, 6-12 parts of dried orange peel, 10-15 parts of poria cocos, 9-15 parts of red ginseng, 60-90 parts of Chinese date, 6-10 parts of cocklebur fruit, 12-16 parts of radix angelicae, 9-12 parts of biond magnolia flower, 3-6 parts of deer-horn gelatin and 3-6 parts of fructus evodiae.

2. The traditional Chinese medicine composition for treating allergic rhinitis according to claim 1, which is prepared from the following raw material medicines in parts by weight: 9 parts of white paeony root, 15 parts of pinellia ternate, 10 parts of dried ginger, 9 parts of cassia twig, 15 parts of ephedra, 15 parts of Chinese magnoliavine fruit, 6 parts of asarum, 9 parts of fried bitter apricot seed, 9 parts of honey-fried licorice root, 50 parts of astragalus mongholicus, 10 parts of divaricate saposhnikovia root, 20 parts of Chinese yam, 15 parts of dogwood, 15 parts of prepared rehmannia root, 10 parts of rhizoma alismatis, 3 parts of black shun slices, 9 parts of tree peony bark, 10 parts of Chinese angelica, 10 parts of rhizoma atractylodis, 6 parts of dried orange peel, 10 parts of poria cocos, 9 parts of red ginseng, 60 parts of Chinese date, 10 parts of cocklebur fruit.

3. The traditional Chinese medicine composition for treating allergic rhinitis according to claim 1, which is characterized by further comprising the following raw material medicines in parts by weight: 30-40 parts of ginger, 6-12 parts of cinnamon, 6-10 parts of raw liquorice, 3-6 parts of caulis clematidis armandii, 10-15 parts of mint, 10-15 parts of dark plum, 9-12 parts of starwort root, 6-9 parts of ligusticum wallichii, 30-45 parts of radix puerariae, 30-45 parts of gypsum, 9-12 parts of radix bupleuri, 5-9 parts of scutellaria baicalensis, 10-15 parts of scorched hawthorn fruit, 10-15 parts of scorched malt, 10-15 parts of scorched medicated leaven and 10-15 parts of stevia rebaudiana.

4. The traditional Chinese medicine composition for treating allergic rhinitis according to claim 3, which is prepared from the following raw material medicines in parts by weight: 9-10 parts of white paeony root, 15-17 parts of pinellia tuber, 10-12 parts of dried ginger, 9-10 parts of cassia twig, 15-17 parts of ephedra herb, 13-15 parts of Chinese magnoliavine fruit, 5-6 parts of asarum, 9-10 parts of fried bitter apricot seed, 9-0 part of honey-fried licorice root, 50-55 parts of astragalus root, 10-12 parts of divaricate saposhnikovia root, 6-8 parts of dried orange peel, 10-12 parts of poria cocos, 30-35 parts of ginger, 10-12 parts of rhizoma atractylodis, 9-10 parts of red ginseng, 60-65 parts of Chinese date, 9-8 parts of moutan bark, 6-8 parts of cinnamon, 20-23 parts of Chinese yam, 15-18 parts of dogwood, 15-18 parts of prepared rehmannia root, 10-12 parts of rhizoma alismatis, 3-4 parts of black cis slices, 10-12 parts of angelica, 9-10 parts, 9-10 parts of cocklebur fruit, 13-15 parts of mint, 13-15 parts of dark plum fruit, 9-10 parts of starwort root, 6-7 parts of ligusticum wallichii, 3-4 parts of deerhorn glue, 12-13 parts of angelica dahurica, 9-10 parts of biond magnolia flower, 30-35 parts of kudzuvine root, 30-35 parts of gypsum, 9-10 parts of radix bupleuri, 5-6 parts of scutellaria baicalensis, 10-12 parts of scorched hawthorn fruit, 10-12 parts of scorched malt, 10-12 parts of scorched medicated leaven and 10-12 parts of stevia rebaudiana.

5. The traditional Chinese medicine composition for treating allergic rhinitis according to claim 3, which is prepared from the following raw material medicines in parts by weight: 9 parts of white paeony root, 15 parts of pinellia tuber, 10 parts of dried ginger, 9 parts of cassia twig, 15 parts of ephedra, 15 parts of Chinese magnoliavine fruit, 6 parts of asarum, 9 parts of fried bitter apricot seed, 9 parts of honey-fried licorice root, 50 parts of astragalus root, 10 parts of divaricate saposhnikovia root, 6 parts of dried orange peel, 10 parts of poria cocos, 30 parts of ginger, 10 parts of rhizoma atractylodis, 9 parts of red ginseng, 60 parts of Chinese date, 9 parts of tree peony bark, 6 parts of cinnamon, 20 parts of Chinese yam, 15 parts of dogwood, 15 parts of prepared rehmannia root, 10 parts of oriental waterplantain rhizome, 3 parts of black cis, 10 parts of Chinese angelica, 10 parts of raw licorice, 3 parts of clematis stem, 6 parts of evodia rutaecarpa fruit, 10 parts of cocklebur fruit, 15 parts of mint, 15 parts of dark plum fruit, 9 parts of starwort root, 6 parts of szechuan lovage rhizome, 3 parts of deerhorn glue, 12.

6. A traditional Chinese medicine composition ointment for treating allergic rhinitis is characterized by being prepared from the traditional Chinese medicine composition of any one of claims 1 to 5.

7. The preparation method of the traditional Chinese medicine composition ointment formula for treating allergic rhinitis, which is disclosed by claim 6, is characterized by comprising the following steps of: the preparation method comprises the steps of taking the raw materials according to the parts by weight, pouring the raw materials into preparation equipment of a traditional Chinese medicine room paste formula, adding water and yellow wine, decocting with strong fire until the pot is boiled, adjusting to slow fire, continuously stirring, decocting for 0.8-1.2 hours, adding maltose, collecting paste, bottling, airing the paste, and sealing to obtain the paste formula.

8. Use of the Chinese medicinal composition for treating allergic rhinitis according to any one of claims 1 to 7 in the preparation of a medicament for treating allergic rhinitis.