CN112675280A - Composition for preventing and treating carsickness and preparation method thereof - Google Patents
Composition for preventing and treating carsickness and preparation method thereof Download PDFInfo
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Abstract
The invention provides a composition for preventing and treating carsickness, which can only comprise an A component or can be used together with the A component and a B component. In the component A, cinnamon, old ginger and dried orange peel are natural medicines for strengthening the spleen and stomach, wherein the old ginger and the dried orange peel are used together, so that the composition has an outstanding curative effect on spleen and stomach qi stagnation syndrome, dyspepsia, abdominal distension and abdominal pain; cortex Cinnamomi has effects of warming spleen and stomach, invigorating primordial qi and yang, and removing cold; the three components can play a good role in preventing and treating carsickness; in the component B, the radix angelicae has the effects of dispelling wind and removing dampness, dredging orifices and relieving pain, and reducing swelling and expelling pus, and the radix angelicae, the lemon juice and the honey are used together, so that the component A can be attached to the navel of a patient and the component B can be attached to the Shanzhong acupoint of the patient aiming at gastric ulcer, gastritis, gastropathy and severe carsickness, and the traditional Chinese medicine composition has a good relieving effect on dizziness and vomiting caused by carsickness and chest distress. The composition provided by the invention can be used repeatedly until the pill is broken and is disposable, and can be used for treating the car sickness of a baby in 0-24 months by the consent of a doctor.
Description
Technical Field
The invention belongs to the technical field of health care products, and particularly relates to a composition for preventing and treating carsickness and a preparation method thereof.
Background
Motion sickness, that is, motion sickness, seasickness, and motion sickness, and diseases caused by rolling, jolting, rotation, and acceleration due to various causes are collectively referred to as motion sickness. The prior art has numerous treatments for motion sickness symptoms, but no good methods of elimination are seen. The prior art has the technical problems of inconvenient use, short duration of drug effect and poor efficacy of the drugs for preventing and treating carsickness.
Disclosure of Invention
In order to solve the technical problems, the invention provides a composition for preventing and treating carsickness, which takes cinnamon, old ginger, dried orange peel, lemon juice and honey as raw materials, wherein the cinnamon, the old ginger and the dried orange peel are natural medicines for strengthening the spleen and the stomach, and the old ginger and the dried orange peel are used together, so that the composition has outstanding curative effects on spleen and stomach qi stagnation syndrome, dyspepsia, abdominal distension and abdominal pain; cortex Cinnamomi has effects of warming spleen and stomach, invigorating primordial qi and yang, and removing cold; the lemon juice and the honey are matched together, so that good carsickness prevention and treatment effects can be achieved. The composition provided by the invention has the advantages of outstanding effect, convenience in use, long efficacy maintaining time and good efficacy of preventing and treating carsickness.
The composition for preventing and treating carsickness, provided by the invention, comprises the following raw materials in parts by weight:
2-5 parts of cinnamon, 2-5 parts of old ginger, 1-3 parts of dried orange peel, 3-10 parts of lemon juice and 3-10 parts of honey.
In the composition for preventing and treating carsickness, cinnamon has the effects of tonifying primordial yang, warming spleen and stomach, removing cold accumulation and promoting blood circulation; the old ginger has the effects of relieving exterior syndrome, dispelling cold, warming middle energizer, arresting vomiting, warming lung, relieving cough, eliminating phlegm, relieving cough and detoxifying; the dried orange peel, pungent in flavor and fragrant in flavor, is good at regulating qi and can enter spleen and lung, so that the dried orange peel, pungent in flavor and fragrant in flavor, can not only disperse lung qi obstruction, but also promote qi circulation and relieve epigastric distention, and has the effects of tonifying spleen and regulating qi; the lemon juice has the effects of reducing phlegm and relieving cough, promoting the production of body fluid and invigorating stomach, brings fresh smell, and calms the mind; the honey has the effects of relaxing bowel, improving immunity and protecting liver, and has certain viscosity, so that the honey is convenient to mix with other raw materials for forming; the composition for preventing and treating carsickness provided by the invention synergistically achieves the effects of strengthening spleen and stomach and helping digestion through the combined action of the cinnamon, the old ginger and the dried orange peel. The traditional Chinese medicine composition can effectively prevent and treat carsickness by regulating the spleen and the stomach, improving the immunity of a human body and relieving or eliminating the symptoms of motion sickness.
In the invention, the cinnamon, the old ginger and the dried orange peel are natural medicines for strengthening the spleen and the stomach, wherein the old ginger and the dried orange peel are used together, so that the traditional Chinese medicine has outstanding curative effects on spleen and stomach qi stagnation syndrome, dyspepsia, abdominal distension and abdominal pain; cortex Cinnamomi has effects of warming spleen and stomach, invigorating primordial qi and yang, and removing cold; the lemon juice and the honey are matched together, so that good carsickness prevention and treatment effects can be achieved.
The preparation method of the composition for preventing and treating carsickness comprises the following steps:
pulverizing cortex Cinnamomi, rhizoma Zingiberis recens and pericarpium Citri Tangerinae into powder, mixing to obtain mixed powder, adding lemon juice and Mel, mixing, and molding to obtain composition for preventing and treating carsickness.
The composition for preventing and treating carsickness, provided by the invention, can be prepared into pills or patches and directly applied to the navel, is convenient to use and can be used repeatedly, and the drug effect is durable.
In the above method for preparing a composition for preventing and treating motion sickness, the particle size of the mixed powder is preferably 150-200 meshes.
The preparation method of the composition for preventing and treating carsickness comprises the following steps:
(1) pulverizing cortex Cinnamomi to obtain cortex Cinnamomi powder, adding cortex Cinnamomi powder into 8-10 times of ethanol, soaking for 6-10h, ultrasonic treating for 30-50min, vacuum filtering, concentrating, and drying to obtain cortex Cinnamomi extract;
the cinnamon extraction method provided by the invention comprises the steps of crushing cinnamon, adding the crushed cinnamon into ethanol, soaking and then carrying out ultrasonic extraction, wherein the obtained cinnamon extract contains cinnamaldehyde, cinnamyl alcohol, caryophyllene and coumarin.
(2) Pulverizing Zingiberis rhizoma, adding 0.6-1.2 times of water, heating to boil, and reflux-extracting to obtain Zingiberis rhizoma extract;
the extraction method of the old ginger provided by the invention can be used for extracting ginger oil in the old ginger, and the obtained old ginger extract contains alpha-zingiberene, beta-bisabolene and curcumene.
Taking dried orange peel, drying, crushing, adding into dilute hydrochloric acid with concentration of 0.1mol/L of 5-10 times, stirring uniformly, then washing with dilute hydrochloric acid with concentration of 0.1mol/L for 2-3 times, then washing with clear water, and drying to obtain pericarpium citri reticulatae powder; adding pericarpium Citri Tangerinae powder into 10-15 times of water, adjusting pH to 2-3, extracting at 85-90 deg.C under stirring for 30-60min, and filtering to obtain residue; drying the filter residue, adding into 8-10 times of methanol, leaching at 80-85 deg.C for 2-3 hr, filtering, and recovering methanol to obtain pericarpium Citri Tangerinae extract; the extraction method of the dried orange peel extract provided by the invention takes methanol as an extractant, and the obtained dried orange peel extract contains abundant hesperidin. Preferably, the concentration of methanol is 90-95%.
(4) And (3) mixing the cinnamon extract obtained in the step (1), the ginger extract obtained in the step (2) and the dried orange peel extract obtained in the step (3) to obtain mixed powder, adding lemon juice and honey, uniformly mixing, and forming to obtain the composition for preventing and treating carsickness.
The composition for preventing and treating carsickness provided by the invention can also be prepared into a patch by extracting the effective components of the raw materials by the method, mixing the effective components with lemon juice and honey, and forming, wherein the patch is directly applied to the navel, is convenient to use and has outstanding drug effect.
The composition for preventing and treating carsickness preferably further comprises the following raw materials in parts by weight:
5-10 parts of angelica dahurica, 3-10 parts of lemon juice, 3-10 parts of honey and 2-3 parts of spice.
The composition for preventing and treating carsickness provided by the invention can also comprise a component B consisting of radix angelicae, lemon juice, honey and spice, wherein the radix angelicae contains imperatorin and isoimperatorin and has the effects of dispelling wind-damp, stopping headache and the like. In the process of preventing and treating carsickness, aiming at patients with gastrointestinal diseases such as gastric ulcer, gastritis and the like, the component A can be attached to the navel, the obtained component B is used for the Shanzhong acupoint, and the component B can assist the component A to achieve more prominent effects of preventing and treating carsickness.
In the component B provided by the invention, the radix angelicae has the effects of dispelling wind and removing dampness, dredging orifices and relieving pain, and reducing swelling and expelling pus, and the radix angelicae, the lemon juice and the honey are used together, so that the component A is pasted on the navel and the component B is pasted on the Danzhong acupoint aiming at people suffering from gastric ulcer, gastritis and gastropathy and severe carsickness, and the component B can play the effects of regulating qi and activating blood, and regulating digestive system and nerve functions, and has a good relieving effect on dizziness and vomiting caused by carsickness and chest distress.
The composition for preventing and treating carsickness, provided by the invention, has a good effect by sticking the component A to the navel aiming at general carsickness people; aiming at the people with severe motion sickness, a method of using the component A and the component B together can be adopted, the component A is attached to the navel, and the component B is attached to the Shanzhong acupoint, so that good prevention and treatment effects are achieved.
The preparation method of the composition for preventing and treating carsickness comprises the following steps:
pulverizing cortex Cinnamomi, rhizoma Zingiberis recens and pericarpium Citri Tangerinae into powder, mixing to obtain mixed powder, adding lemon juice and Mel, and molding to obtain component A of the composition for preventing and treating carsickness;
crushing the angelica dahurica to obtain angelica dahurica powder, adding lemon juice, honey and spice, uniformly mixing, and forming to obtain the component B of the composition for preventing and treating carsickness.
The preparation method of the composition for preventing and treating carsickness comprises the following steps:
(1) pulverizing cortex Cinnamomi to obtain cortex Cinnamomi powder, adding cortex Cinnamomi powder into 8-10 times of ethanol, soaking for 6-10h, ultrasonic treating for 30-50min, vacuum filtering, concentrating, and drying to obtain cortex Cinnamomi extract;
the cinnamon extraction method provided by the invention comprises the steps of crushing cinnamon, adding the crushed cinnamon into ethanol, soaking and then carrying out ultrasonic extraction, wherein the obtained cinnamon extract contains cinnamaldehyde, cinnamyl alcohol, caryophyllene and coumarin.
(2) Pulverizing Zingiberis rhizoma, adding 0.6-1.2 times of water, heating to boil, and reflux-extracting to obtain Zingiberis rhizoma extract;
the extraction method of the old ginger provided by the invention can be used for extracting ginger oil in the old ginger, and the obtained old ginger extract contains alpha-zingiberene, beta-bisabolene and curcumene.
(3) Taking dried orange peel, drying, crushing, adding into dilute hydrochloric acid with concentration of 0.1mol/L of 5-10 times, stirring uniformly, then washing with dilute hydrochloric acid with concentration of 0.1mol/L for 2-3 times, then washing with clear water, and drying to obtain pericarpium citri reticulatae powder; adding pericarpium Citri Tangerinae powder into 10-15 times of water, adjusting pH to 2-3, extracting at 85-90 deg.C under stirring for 30-60min, and filtering to obtain residue; drying the filter residue, adding into 8-10 times of methanol, leaching at 80-85 deg.C for 2-3 hr, filtering, and recovering methanol to obtain pericarpium Citri Tangerinae extract;
(4) mixing the cinnamon extract obtained in the step (1), the ginger extract obtained in the step (2) and the dried orange peel extract obtained in the step (3) to obtain mixed powder, adding lemon juice and honey, uniformly mixing, and forming to obtain a component A of the composition for preventing and treating carsickness;
(5) pulverizing radix Angelicae Dahuricae, adding into 6-10 times of ethanol, extracting for 2-3 times (2-3 hr each time), mixing filtrates, concentrating, and drying to obtain radix Angelicae Dahuricae extract;
the angelica dahurica extract provided by the invention contains imperatorin and isoimperatorin, and has good effects of diminishing inflammation and relieving pain.
Preferably, the concentration of ethanol is 75-80%.
(6) And (3) uniformly mixing the angelica dahurica extract obtained in the step (5) with lemon juice, honey and spice, and forming to obtain a component B of the composition for preventing and treating carsickness.
According to the preparation method provided by the invention, the A component and the B component are respectively obtained by extracting the effective substances in the components, and then mixing and molding the effective substances with other raw materials such as lemon juice, honey and the like, so that the effective components of the medicine can play a better role, and the prevention and treatment effects are improved.
The composition for preventing and treating carsickness provided by the invention needs to follow the medical advice when aiming at 0-24 months of baby carsickness.
The invention has the beneficial effects that:
1. the cinnamon in the composition for preventing and treating the carsickness contains cinnamaldehyde, cinnamyl alcohol, caryophyllene and coumarin; has effects in invigorating primordial yang, warming spleen and stomach, removing cold accumulation, and promoting blood circulation; the old ginger contains alpha-zingiberene, beta-bisabolene and curcumene; has effects in relieving exterior syndrome, dispelling cold, warming middle warmer, relieving vomit, warming lung, relieving cough, eliminating phlegm, relieving cough, and removing toxic substance; pericarpium Citri Tangerinae contains hesperidin; the dried orange peel, pungent in flavor and fragrant in flavor, is good at regulating qi and can enter spleen and lung, so that the dried orange peel, pungent in flavor and fragrant in flavor, can not only disperse lung qi obstruction, but also promote qi circulation and relieve epigastric distention, and has the effects of tonifying spleen and regulating qi; the lemon juice has the effects of reducing phlegm and relieving cough, promoting the production of body fluid and invigorating stomach, brings fresh smell, and calms the mind; the honey has the effects of relaxing bowel, improving immunity and protecting liver, and has certain viscosity, so that the honey is convenient to mix with other raw materials for forming; the composition for preventing and treating carsickness provided by the invention synergistically achieves the effects of strengthening spleen and stomach and helping digestion through the combined action of the cinnamon, the old ginger and the dried orange peel. The traditional Chinese medicine composition can effectively prevent and treat carsickness by regulating the spleen and the stomach, improving the immunity of a human body and relieving or eliminating the symptoms of motion sickness.
2. The composition for preventing and treating carsickness, provided by the invention, can be a composition which only comprises the component A or can simultaneously comprise the component A and the component B; aiming at general carsickness people, the A component can play a good role by being stuck to the navel; aiming at the people with severe motion sickness, a method of using the component A and the component B together can be adopted, the component A is attached to the navel, and the component B is attached to the Shanzhong acupoint, so that good prevention and treatment effects are achieved.
3. The composition for preventing and treating carsickness, provided by the invention, is simple and convenient to use, has a lasting drug effect, is environment-friendly, can be repeatedly used until pills are broken, is disposable, has an outstanding effect and does not have side effects.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be described in detail below. It is to be understood that the described embodiments are merely exemplary of the invention, and not restrictive of the full scope of the invention. All other embodiments, which can be derived by a person skilled in the art from the examples given herein without any inventive step, are within the scope of the present invention.
Example 1
A carsickness prevention and treatment patch for carsickness comprises the following raw materials by weight:
2g of cinnamon, 2g of old ginger, 1g of dried orange peel, 10g of lemon juice and 10g of honey.
The preparation method of the carsickness prevention and treatment patch comprises the following steps:
pulverizing cortex Cinnamomi, rhizoma Zingiberis recens and pericarpium Citri Tangerinae into powder, mixing to obtain mixed powder with particle size of 150 meshes and 200 meshes, adding lemon juice and Mel, mixing, molding, and making into pill to obtain the patch for preventing and treating carsickness.
Example 2
A carsickness prevention and treatment patch for carsickness comprises the following raw materials by weight:
5g of cinnamon, 5g of old ginger, 3g of dried orange peel, 3g of lemon juice and 3g of honey.
The preparation method of the carsickness prevention and treatment patch comprises the following steps:
(1) pulverizing cortex Cinnamomi to obtain cortex Cinnamomi powder, adding cortex Cinnamomi powder into 8 times of ethanol, soaking for 6 hr, ultrasonic treating for 30min, vacuum filtering, concentrating, and drying to obtain cortex Cinnamomi extract;
(2) pulverizing Zingiberis rhizoma, adding 0.6 times of water, heating to boil, and reflux-extracting to obtain Zingiberis rhizoma extract;
(3) taking pericarpium citri reticulatae, drying, crushing, adding into dilute hydrochloric acid with the concentration of 5 times of 0.1mol/L, stirring uniformly, then washing for 2 times by using dilute hydrochloric acid with the concentration of 0.1mol/L, washing by using clear water, and drying to obtain pericarpium citri reticulatae powder; adding pericarpium Citri Tangerinae powder into 10 times of water, adjusting pH to 2, stirring and extracting at 85 deg.C for 30min, and filtering to obtain filter residue; drying the filter residue, adding into 8 times of 90% methanol by weight, leaching at 80 deg.C for 2 hr, filtering, and recovering methanol to obtain pericarpium Citri Tangerinae extract;
(4) and (3) mixing the cinnamon extract obtained in the step (1), the ginger extract obtained in the step (2) and the dried orange peel extract obtained in the step (3) to obtain mixed powder, adding lemon juice and honey, uniformly mixing, and forming to obtain the carsickness prevention and treatment plaster.
Example 3
A carsickness prevention and treatment patch for carsickness comprises the following raw materials by weight:
4g of cinnamon, 4g of old ginger, 2g of dried orange peel, 4g of lemon juice and 5g of honey.
The preparation method of the carsickness prevention and treatment patch comprises the following steps:
(1) pulverizing cortex Cinnamomi to obtain cortex Cinnamomi powder, adding cortex Cinnamomi powder into 10 times of ethanol, soaking for 10 hr, ultrasonic treating for 50min, vacuum filtering, concentrating, and drying to obtain cortex Cinnamomi extract;
(2) pulverizing Zingiberis rhizoma, adding 1.2 times of water, heating to boil, and reflux-extracting to obtain Zingiberis rhizoma extract;
(3) taking pericarpium citri reticulatae, drying, crushing, adding into dilute hydrochloric acid with the concentration of 0.1mol/L which is 10 times of that of the pericarpium citri reticulatae, stirring uniformly, then washing for 3 times by using the dilute hydrochloric acid with the concentration of 0.1mol/L, then washing by using clear water, and drying to obtain pericarpium citri reticulatae powder; adding pericarpium Citri Tangerinae powder into 15 times of water, adjusting pH to 3, stirring and extracting at 90 deg.C for 60min, and filtering to obtain filter residue; drying the filter residue, adding into 8 times of 90% methanol by weight, leaching at 85 deg.C for 3 hr, filtering, and recovering methanol to obtain pericarpium Citri Tangerinae extract;
(4) and (3) mixing the cinnamon extract obtained in the step (1), the ginger extract obtained in the step (2) and the dried orange peel extract obtained in the step (3) to obtain mixed powder, adding lemon juice and honey, uniformly mixing, and forming to obtain the carsickness prevention and treatment plaster.
Example 4
The carsickness prevention and treatment patch comprises a component A and a component B, wherein the component A comprises the following raw materials in parts by weight:
2g of cinnamon, 2g of old ginger, 1g of dried orange peel, 10g of lemon juice and 10g of honey;
the component B comprises the following raw materials in parts by weight:
5g of angelica dahurica, 10g of lemon juice, 10g of honey and 3g of spices.
The preparation method of the carsickness prevention and treatment patch comprises the following steps:
pulverizing cortex Cinnamomi, rhizoma Zingiberis recens and pericarpium Citri Tangerinae into powder, mixing to obtain mixed powder with particle size of 150 meshes and 200 meshes, adding lemon juice and Mel, and molding to obtain component A of the composition for preventing and treating carsickness;
crushing the angelica dahurica to obtain angelica dahurica powder with the particle size of 150-.
Example 5
The carsickness prevention and treatment patch comprises a component A and a component B, wherein the component A comprises the following raw materials in parts by weight:
5g of cinnamon, 5g of old ginger, 3g of dried orange peel, 3g of lemon juice and 3g of honey.
The component B comprises the following raw materials in parts by weight:
10g of angelica dahurica, 3g of lemon juice, 3g of honey and 2g of spice.
The preparation method of the carsickness prevention and treatment patch comprises the following steps:
(1) pulverizing cortex Cinnamomi to obtain cortex Cinnamomi powder, adding cortex Cinnamomi powder into 10 times of ethanol, soaking for 10 hr, ultrasonic treating for 50min, vacuum filtering, concentrating, and drying to obtain cortex Cinnamomi extract;
(2) pulverizing Zingiberis rhizoma, adding 1.2 times of water, heating to boil, and reflux-extracting to obtain Zingiberis rhizoma extract;
(3) taking pericarpium citri reticulatae, drying, crushing, adding into dilute hydrochloric acid with the concentration of 0.1mol/L which is 10 times of that of the pericarpium citri reticulatae, stirring uniformly, then washing for 3 times by using the dilute hydrochloric acid with the concentration of 0.1mol/L, then washing by using clear water, and drying to obtain pericarpium citri reticulatae powder; adding pericarpium Citri Tangerinae powder into 15 times of water, adjusting pH to 3, stirring and extracting at 90 deg.C for 60min, and filtering to obtain filter residue; drying the filter residue, adding into 8 times of 90% methanol by weight, leaching at 85 deg.C for 3 hr, filtering, and recovering methanol to obtain pericarpium Citri Tangerinae extract;
(4) mixing the cinnamon extract obtained in the step (1), the ginger extract obtained in the step (2) and the dried orange peel extract obtained in the step (3) to obtain mixed powder, adding lemon juice and honey, uniformly mixing, and forming to obtain a component A for preventing and treating carsickness;
(5) pulverizing radix Angelicae Dahuricae, adding into 6 times of ethanol, extracting for 2 times (2 hr each time), mixing filtrates, concentrating, and drying to obtain radix Angelicae Dahuricae extract;
(6) and (3) uniformly mixing the angelica dahurica extract obtained in the step (5) with lemon juice, honey and spice, and forming to obtain a component B of the composition for preventing and treating carsickness.
Example 6
The carsickness prevention and treatment patch comprises a component A and a component B, wherein the component A comprises the following raw materials in parts by weight:
4g of cinnamon, 4g of old ginger, 1g of dried orange peel, 4g of lemon juice and 4g of honey;
the component B comprises the following raw materials in parts by weight:
8g of angelica dahurica, 4g of lemon juice, 3g of honey and 2g of spice.
The preparation method of the carsickness prevention and treatment patch comprises the following steps:
(1) pulverizing cortex Cinnamomi to obtain cortex Cinnamomi powder, adding cortex Cinnamomi powder into 10 times of ethanol, soaking for 10 hr, ultrasonic treating for 50min, vacuum filtering, concentrating, and drying to obtain cortex Cinnamomi extract;
(2) pulverizing Zingiberis rhizoma, adding 1.2 times of water, heating to boil, and reflux-extracting to obtain Zingiberis rhizoma extract;
(3) taking pericarpium citri reticulatae, drying, crushing, adding into dilute hydrochloric acid with the concentration of 0.1mol/L which is 10 times of that of the pericarpium citri reticulatae, stirring uniformly, then washing for 3 times by using the dilute hydrochloric acid with the concentration of 0.1mol/L, then washing by using clear water, and drying to obtain pericarpium citri reticulatae powder; adding pericarpium Citri Tangerinae powder into 15 times of water, adjusting pH to 3, stirring and extracting at 90 deg.C for 60min, and filtering to obtain filter residue; drying the filter residue, adding into 8 times of 90% methanol by weight, leaching at 85 deg.C for 3 hr, filtering, and recovering methanol to obtain pericarpium Citri Tangerinae extract;
(4) mixing the cinnamon extract obtained in the step (1), the ginger extract obtained in the step (2) and the dried orange peel extract obtained in the step (3) to obtain mixed powder, adding lemon juice and honey, uniformly mixing, and forming to obtain a component A for preventing and treating carsickness;
(5) pulverizing radix Angelicae Dahuricae, adding into 6 times of ethanol, extracting for 2 times (2 hr each time), mixing filtrates, concentrating, and drying to obtain radix Angelicae Dahuricae extract;
(6) and (3) uniformly mixing the angelica dahurica extract obtained in the step (5) with lemon juice, honey and spice, and forming to obtain a component B of the composition for preventing and treating carsickness.
Comparative example 1
A carsickness prevention and treatment patch for carsickness comprises the following raw materials by weight:
2g of old ginger, 1g of dried orange peel and 10g of honey.
The preparation method of the carsickness prevention and treatment patch comprises the following steps:
pulverizing old ginger and tangerine peel into powder, mixing to obtain mixed powder with the particle size of 150-200 meshes, then adding honey, uniformly mixing, forming and preparing into pills to obtain the carsickness prevention and treatment plaster.
Test examples
1. The inventor compares the carsickness patches obtained in the embodiment 1 and the comparative example 1 to find that the carsickness patch obtained in the comparative example 1 is a conventional commonly-used carsickness patch which takes old ginger and dried orange peel as main components and is used for navel, the effect is slow, the action time is short, the effect is not ideal, and the carsickness patch obtained in the embodiment 1 is pasted on the navel, the effect is fast, the action time is long, the patch can be repeatedly used for about 30 days, and the effect is remarkable. Therefore, the carsickness prevention and treatment patch provided by the invention can effectively improve the carsickness prevention and treatment effects through the interaction of the components.
Typical cases
1. If a woman suffers from stomach diseases, sudden belly swelling pain, pale face and incapability of standing, the carsickness patch A component obtained in the embodiment 4 of the invention is pasted on the navel, the B component is pasted on the Shanzhong acupoint, and the woman can get up, walk and get home on a train after half an hour.
2. Wu and women have symptoms of dull pain of the belly for about 3 days, the disease condition is aggravated, the women cannot stand and lie on a table, so the carsickness obtained by pasting the medicine disclosed by the embodiment 2 of the invention is pasted on the belly button, the symptoms are obviously relieved after about 15 minutes, and the women can stand and walk.
3. For a woman who has a bad breath due to hot weather, who has a cold food, is painful in the belly, wants to vomit, cannot vomit, is dizzy, and cannot stand alone, the carsickness obtained in the embodiment 1 of the invention is pasted on the belly button, the symptoms are relieved after 20 minutes, vomit is vomited, and the woman can walk to sit in a car to go to a hospital.
By combining the three life cases, the carsickness plaster provided by the invention can be fully demonstrated to play a good role in warming the stomach, exhausting air, preventing and treating carsickness.
The above description is only for the specific embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present invention, and all the changes or substitutions should be covered within the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the appended claims.
Claims (9)
1. The composition for preventing and treating carsickness is characterized by comprising the following raw materials in parts by weight:
2-5 parts of cinnamon, 2-5 parts of old ginger, 1-3 parts of dried orange peel, 3-10 parts of lemon juice and 3-10 parts of honey.
2. The composition for preventing and treating carsickness according to claim 1, wherein the composition further comprises the following raw materials B in parts by weight:
5-10 parts of angelica dahurica, 3-10 parts of lemon juice, 3-10 parts of honey and 2-3 parts of spice.
3. The method for preparing a composition for preventing and treating motion sickness according to claim 1, wherein the method comprises the steps of:
pulverizing cortex Cinnamomi, rhizoma Zingiberis recens and pericarpium Citri Tangerinae into powder, mixing to obtain mixed powder, adding lemon juice and Mel, mixing, and molding to obtain composition for preventing and treating carsickness.
4. The method for preparing a composition for the prevention and treatment of motion sickness according to claim 3, wherein the particle size of the mixed powder is 150-200 mesh.
5. The method for preparing a composition for preventing and treating motion sickness according to claim 1, wherein the method comprises the steps of:
(1) pulverizing cortex Cinnamomi to obtain cortex Cinnamomi powder, adding cortex Cinnamomi powder into 8-10 times of ethanol, soaking for 6-10h, ultrasonic treating for 30-50min, vacuum filtering, concentrating, and drying to obtain cortex Cinnamomi extract;
(2) pulverizing Zingiberis rhizoma, adding 0.6-1.2 times of water, heating to boil, and reflux-extracting to obtain Zingiberis rhizoma extract;
(3) taking dried orange peel, drying, crushing, adding into dilute hydrochloric acid with concentration of 0.1mol/L of 5-10 times, stirring uniformly, then washing with dilute hydrochloric acid with concentration of 0.1mol/L for 2-3 times, then washing with clear water, and drying to obtain pericarpium citri reticulatae powder; adding pericarpium Citri Tangerinae powder into 10-15 times of water, adjusting pH to 2-3, extracting at 85-90 deg.C under stirring for 30-60min, and filtering to obtain residue; drying the filter residue, adding into 8-10 times of methanol, leaching at 80-85 deg.C for 2-3 hr, filtering, and recovering methanol to obtain pericarpium Citri Tangerinae extract;
(4) and (3) mixing the cinnamon extract obtained in the step (1), the ginger extract obtained in the step (2) and the dried orange peel extract obtained in the step (3) to obtain mixed powder, adding lemon juice and honey, uniformly mixing, and forming to obtain the composition for preventing and treating carsickness.
6. The method for preparing a composition for the prevention and treatment of motion sickness according to claim 5, wherein the concentration of the methanol in the step (3) is 90-95%.
7. The method for preparing a composition for preventing and treating motion sickness according to claim 2, wherein the method comprises the steps of:
pulverizing cortex Cinnamomi, rhizoma Zingiberis recens and pericarpium Citri Tangerinae into powder, mixing to obtain mixed powder, adding lemon juice and Mel, and molding to obtain component A of the composition for preventing and treating carsickness;
crushing the angelica dahurica to obtain angelica dahurica powder, adding lemon juice, honey and spice, uniformly mixing, and forming to obtain the component B of the composition for preventing and treating carsickness.
8. The method for preparing a composition for preventing and treating motion sickness according to claim 2, wherein the method comprises the steps of:
(1) pulverizing cortex Cinnamomi to obtain cortex Cinnamomi powder, adding cortex Cinnamomi powder into 8-10 times of ethanol, soaking for 6-10h, ultrasonic treating for 30-50min, vacuum filtering, concentrating, and drying to obtain cortex Cinnamomi extract;
(2) pulverizing Zingiberis rhizoma, adding 0.6-1.2 times of water, heating to boil, and reflux-extracting to obtain Zingiberis rhizoma extract;
(3) taking dried orange peel, drying, crushing, adding into dilute hydrochloric acid with concentration of 0.1mol/L of 5-10 times, stirring uniformly, then washing with dilute hydrochloric acid with concentration of 0.1mol/L for 2-3 times, then washing with clear water, and drying to obtain pericarpium citri reticulatae powder; adding pericarpium Citri Tangerinae powder into 10-15 times of water, adjusting pH to 2-3, extracting at 85-90 deg.C under stirring for 30-60min, and filtering to obtain residue; drying the filter residue, adding into 8-10 times of methanol, leaching at 80-85 deg.C for 2-3 hr, filtering, and recovering methanol to obtain pericarpium Citri Tangerinae extract;
(4) mixing the cinnamon extract obtained in the step (1), the ginger extract obtained in the step (2) and the dried orange peel extract obtained in the step (3) to obtain mixed powder, adding lemon juice and honey, uniformly mixing, and forming to obtain a component A of the composition for preventing and treating carsickness;
(5) pulverizing radix Angelicae Dahuricae, adding into 6-10 times of ethanol, extracting for 2-3 times (2-3 hr each time), mixing filtrates, concentrating, and drying to obtain radix Angelicae Dahuricae extract;
(6) and (3) uniformly mixing the angelica dahurica extract obtained in the step (5) with lemon juice, honey and spice, and forming to obtain a component B of the composition for preventing and treating carsickness.
9. The method for preparing a composition for preventing and treating motion sickness according to claim 8, wherein the concentration of the ethanol in the step (5) is 75 to 80%.
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