CN112655710A - Pesticide composition, application thereof and herbicide - Google Patents
Pesticide composition, application thereof and herbicide Download PDFInfo
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Abstract
The invention relates to the field of pesticides, and discloses a pesticide composition, and application and a herbicide thereof, wherein the composition contains a component A and a component B with weeding effective amounts, and the weight ratio of the component A to the component B is 1: (0.5-70), wherein the component A is a compound 168 shown in a formula (I), and the component B is cyhalofop-butyl shown in a formula (II); optionally, the composition also contains a component C shown in a formula (III). The pesticide composition and the herbicide provided by the invention can overcome the existing resistance of gramineous weeds such as barnyard grass, moleplant seed, large crabgrass, leersia hexandra and the like to the aryloxyphenoxypropionic acid ester herbicide such as cyhalofop-butyl in rice fieldsThe herbicide has the advantages of overcoming the defect that the herbicide easily causes phytotoxicity to crops such as rice when the cyclohexenone herbicide is used for preventing and controlling weeds, having excellent weeding effect and having good safety to the crops such as the rice.
Description
Technical Field
The invention relates to the field of pesticides, and particularly relates to a pesticide composition, application of the pesticide composition in weed control and a herbicide.
Background
The grass weeds such as barnyard grass, moleplant seed, large crabgrass, rice leersia hexandra and the like in the paddy field are seriously damaged. The existing control methods mainly comprise closed treatment and stem and leaf spray treatment, wherein stem and leaf spray is adopted to control the weeds as a main means. However, the weeds have certain resistance to conventional medicaments such as quinclorac, penoxsulam, metamifop and the like, the control difficulty is increased, and the control cost is increased.
Cyhalofop-butyl is an aryloxy phenoxy propionate which is only a pair of herbicides with high rice safety and is of a systemic conduction type and is mainly absorbed by plant stems and leaves. The composition can effectively prevent and control the moleplant seed, the small-age barnyard grass and the large crabgrass, and the application of the moleplant seed is limited to a certain extent because the composition can only prevent and control the small-age barnyard grass and the large crabgrass and the moleplant seed also generates certain resistance to the small-age barnyard grass and the small crabgrass.
The compound 168 (the name of English is (R) -2- (1- (2- (4-chlorophenoxy) proxyimino) -butyl) -5- (2- (ethylhio) propyl) -3-hydroxycyclohexex-2-one) is also a cyclohexenone herbicide, and acts as an ACCase inhibitor. Is mainly used for preventing and controlling barnyard grass, large crabgrass, moleplant seed and golden green bristlegrass in the paddy field. The structural formula is as follows:
disclosure of Invention
One of the purposes of the invention is to overcome the defect of the prior art that gramineous weeds such as barnyard grass, moleplant seed, large crabgrass, and Leersia graminis have resistance to aryloxyphenoxypropionate herbicides such as cyhalofop-butyl.
The invention also aims to overcome the defects that the effect of using the cyclohexenone herbicide compound 168 on controlling broadleaf weeds and cyperaceae weeds in paddy fields is not ideal, and the weeds (especially gramineous weeds) are easily damaged by pesticide on crops such as paddy when the dosage concentration is increased in the prior art.
The inventor of the invention finds in research that cyhalofop-butyl is specifically mixed with a cyclohexenone herbicide compound 168 in a weight ratio of (0.5-70): 1, can overcome the defect of resistance when only cyhalofop-butyl is used for preventing and controlling weeds (particularly grassy weeds) and can prevent the defect of easy phytotoxicity on crops such as rice when cyclohexenone herbicides are used, and can effectively prevent and control the malignant weeds such as the elderberry, the crabgrass, the resistant barnyard grass and the paspalum distichum which can not be prevented and controlled when only cyhalofop-butyl is used in the prior art. Based on this, the inventors of the present invention have completed the technical solution of the present invention.
In view of the above two objects, the present invention provides a novel pesticidal composition and a herbicide which have an excellent controlling effect on weeds in crops, particularly grassy weeds, and are highly safe.
In order to achieve the above object, one aspect of the present invention provides a pesticide composition comprising a herbicidally effective amount of a component a and a component B, wherein the component a and the component B are present in a weight ratio of 1: (0.5-70), wherein the component A is a compound 168 shown in a formula (I), and the component B is cyhalofop-butyl shown in a formula (II); optionally, the composition also contains a component C shown in a formula (III);
in another aspect, the invention provides the use of the aforementioned pesticide composition for controlling weeds.
In a further aspect of the present invention, there is provided a herbicide comprising an active ingredient and an adjuvant, wherein the active ingredient is the pesticide composition according to the first aspect of the present invention.
The pesticide composition and the herbicide provided by the invention can overcome the defect that gramineous weeds such as barnyard grass, moleplant seed, large crabgrass, leersia hexandra, green bristlegrass and reed in a paddy field have resistance to aryloxyphenoxypropionate herbicides such as cyhalofop-butyl, can overcome the defect that the cyclohexenone herbicides are easy to cause phytotoxicity to crops such as rice when used for preventing and controlling the weeds, have an obvious excellent weeding effect, and have good safety to the crops such as the rice.
Compared with the prior art, the pesticide composition and the herbicide provided by the invention can ensure a good weeding effect on the premise of reducing the pesticide dosage, so that the cost can be saved.
Particularly, the pesticide composition and the herbicide provided by the invention can effectively prevent and control the malignant weeds such as older moleplant seeds, large crabgrass, resistant barnyard grass and paspalum distichum which cannot be prevented and controlled by singly using the cyhalofop-butyl in the prior art.
Detailed Description
The endpoints of the ranges and any values disclosed herein are not limited to the precise range or value, and such ranges or values should be understood to encompass values close to those ranges or values. For ranges of values, between the endpoints of each of the ranges and the individual points, and between the individual points may be combined with each other to give one or more new ranges of values, and these ranges of values should be considered as specifically disclosed herein.
As described above, the first aspect of the present invention provides a pesticidal composition comprising a herbicidally effective amount of component a and component B in a weight ratio of 1: (0.5-70), wherein the component A is a compound 168 shown in a formula (I), and the component B is cyhalofop-butyl shown in a formula (II); optionally, the composition also contains a component C shown in a formula (III);
the components in the pesticide composition provided by the invention can be stored in a mixed way or can be stored separately, and the composition provided by the invention comprises the steps of storing the components in the pesticide composition respectively and mixing the components for use in a tank mixing way.
Preferably, in the pesticide composition, the content weight ratio of the component A to the component B is 1: (1-60); more preferably 1: (1.02-50).
The inventors of the present invention have found that, in particular, a catalyst containing, by mass, 1: (1.02-50) the pesticide composition of the component A and the component B can be used for preventing and controlling weeds in paddy fields, and the formed pesticide composition has a broad-spectrum effect on gramineous weeds in paddy fields and is very safe for paddy.
Preferably, in the pesticide composition, the weight ratio of the component a to the component C is 1: (0.1-1).
In fact, the component C in the herbicidal composition of the present invention does not have a good effect of controlling weeds, but, due to the limitations of the existing processes, it is difficult to achieve 100% purity of the component a obtained in the prior art and to control the cost, and a certain amount of the component C is basically contained, so that the herbicidal composition of the present invention optionally contains the component C, and the inventors of the present invention have found that when the weight ratio of the component C to the component a is not more than 0.5: 1, the herbicidal compositions of the present invention all have excellent weed control effects and are highly safe to crops.
As mentioned above, the second aspect of the present invention provides the use of the aforementioned pesticidal composition for controlling weeds.
Preferably, the weeds are grassy weeds.
Preferably, the grass weeds are one or more of moleplant seed, large crabgrass, barnyard grass, green bristlegrass, reed, rice grass, paspalum distichum and eleusine indica.
As mentioned above, the third aspect of the present invention provides a herbicide, which consists of an active ingredient and an adjuvant, wherein the active ingredient comprises the pesticide composition of the first aspect.
Preferably, the content of the active ingredient is preferably 5 to 100 wt% based on the total weight of the herbicide; more preferably 15 to 98 wt%.
Preferably, in the herbicide, the adjuvant is at least one of an emulsifier, a dispersant, a wetting agent, a spreader, a stabilizer, a defoamer, a synergist, a penetrant, a binder, a safener, a carrier and a filler.
Preferably, the herbicide of the present invention has a formulation selected from at least one of wettable powder, soluble powder, emulsifiable concentrate, aqueous suspension, dispersible oil suspension, aqueous emulsion, microemulsion and water dispersible granule.
Several preferred embodiments of the herbicides of the invention are provided below:
embodiment mode 1:
the herbicide is in the form of emulsifiable concentrate, and the content of the active ingredient is 1-60 wt% based on the total weight of the herbicide; preferably 5 to 40 wt%.
Embodiment mode 2:
the herbicide is in the form of an aqueous emulsion, and the content of the active ingredients is 1-50 wt% based on the total weight of the herbicide; preferably 5 to 35 wt%.
Embodiment mode 3:
the herbicide is an oil suspending agent, and the content of the active ingredients is 1-40 wt% based on the total weight of the herbicide; preferably 5 to 35 wt%.
The method for forming the formulations such as emulsifiable solution, aqueous emulsion and oil suspension agent is not particularly limited, and the person skilled in the art can form various formulations provided by the invention by referring to the method provided in the modern pesticide formulation processing technology (edited by Liu Guang text, chemical industry Press).
The component B of the present invention may be in other active forms of the foregoing, for example, in the form of an ester or salt thereof, and the like.
Preferably, the herbicide of the present invention is prepared by separately storing the components of the pesticidal composition forming the active ingredient and mixing them together as a tank mix.
The present invention will be described in detail below by way of examples.
In the following examples, various raw materials used were commercially available unless otherwise specified.
The preparation method of (R) -2- (4-chloro-phenoxy) -propoxylamine comprises the following steps:
adding p-chlorophenol (0.515mol), potassium carbonate (0.5mol) and petroleum ether (500ml) into a reaction bottle for refluxing and water diversion, reacting for 30min, dropwise adding (S) -methyl chloropropionate (0.5mol), after dropwise adding, continuously refluxing and water diversion for 12h at 65 ℃, adding water (100ml) after HPLC (high performance liquid chromatography) detects that the methyl chloropropionate is basically unchanged, stirring, standing for demixing, washing an organic phase with water twice, and removing the petroleum ether under reduced pressure to obtain the 2-p-chlorophenoxypropionic acid methyl ester.
Adding sodium borohydride (1mol), anhydrous calcium chloride (0.05mol), toluene (500ml) and ethanol (500ml) into a reaction bottle, uniformly mixing, continuously dropwise adding the prepared methyl 2-p-chlorophenoxypropionate (0.5mol), reacting for 4 hours at 30 ℃ after the dropwise adding is finished, adding 20 wt% ammonium chloride aqueous solution (1mol calculated by pure substances) for hydrolysis reaction after HPLC (high performance liquid chromatography) detects that the content of the methyl 2-p-chlorophenoxypropionate is less than 1 wt%, wherein the hydrolysis temperature is 30 ℃, the hydrolysis time is 1 hour, standing and layering after the reaction is finished, extracting twice by using toluene, combining organic phases, and cleaning and removing a solvent to obtain (R)2- (4-chlorophenoxy) -propanol.
Adding 2- (4-chloro-phenoxy) -propanol (0.5mol), triethylamine (0.585mol) and toluene (500ml) into a reaction bottle, dropwise adding methanesulfonyl chloride (0.6mol), reacting for 3h at 30 ℃, adding water for stirring and layering after detecting that the content of 2- (4-chloro-phenoxy) -propanol is less than 1 wt% by HPLC (high performance liquid chromatography), and removing toluene from an organic phase to obtain methanesulfonic acid [2- (4-chloro-phenoxy) -propyl ] ester.
Adding methanesulfonic acid [2- (4-chloro-phenoxy) -propyl ] ester (0.5mol), acetohydroxamic acid (0.85mol) and DMSO (600ml) into a reaction bottle, stirring to dissolve, adding sodium hydroxide (2mol), reacting at 60 ℃ for 10h, detecting by HPLC that the methanesulfonic acid [2- (4-chloro-phenoxy) -propyl ] ester is basically unchanged, distilling to remove DMSO, dissolving residual organic phase in the bottle with water, extracting with dichloromethane for three times, and removing dichloromethane to obtain N- [2- (4-chloro-phenoxy) -propoxy ] acetamide.
Adding N- [2- (4-chloro-phenoxy) -propoxy ] acetamide (0.5mol) and ethanol (100ml) into a reaction bottle, dropwise adding 30 wt% of hydrochloric acid (1mol calculated by hydrogen ions), reacting for 5h at 30 ℃, removing the ethanol in the system after detecting the content of the N- [2- (4-chloro-phenoxy) -propoxy ] acetamide by HPLC (high performance liquid chromatography) to be less than 1 wt%, adding 30 wt% of NaOH to adjust the pH value to 14, extracting twice by using dichloromethane, and removing the dichloromethane to obtain (R) -2- (4-chloro-phenoxy) -propoxylamine, wherein the optical purity is not less than 95%.
The preparation method of (S) -2- (4-chloro-phenoxy) -propoxylamine comprises the following steps:
similar to the preparation of (R) -2- (4-chloro-phenoxy) -propoxylamine, except that: replacing (S) -methyl chloropropionate with (R) -methyl chloropropionate to prepare (S) -2- (4-chloro-phenoxy) -propoxylamine, wherein the optical purity is more than or equal to 95%.
2- (1-butyryl) -5- (2-ethylmercaptopropyl) -1, 3-cyclohexanedione: purchased from Shandong Xianda agrichemical Co., Ltd.
Mass spectrometry: manufactured by icpms-2030 Shimadzu.
400M nuclear magnetism: manufactured by Bruker.
Automatic polarimeters: WZZ-2S, Shanghai instrumental electrical production.
The raw materials used in the following examples are specifically as follows:
and (2) component A:
compound 168: the synthesis in laboratory is as follows:
the specific synthesis method comprises the following steps: to a reaction flask were added 5.5g of (R) -2- (4-chloro-phenoxy) -propoxyamine, 7.3g of 2- (1-butyryl) -5- (2-ethylmercaptopropyl) -1, 3-cyclohexanedione and 100.0ml of petroleum ether, the temperature was kept constant at 35 ℃ for 6 hours, 100.0ml of saturated saline was added to the system, and the aqueous phase was adjusted to pH 1 or so with 20 wt% hydrochloric acid, and after stirring sufficiently, the layers were separated, the organic phase was washed with saline to neutrality, and the solvent was removed to obtain a yellow viscous liquid, which was determined to have an optical purity of more than 95% by mass spectrometry, 400M nuclear magnetism and an automatic analyzer.
And (B) component:
cyhalofop-butyl: purchased from Jiangsu Zhongqi science and technology, Inc.
And (3) component C: the synthesis in laboratory is as follows:
the specific synthesis method comprises the following steps: to a reaction flask were added 5.5g of (S) -2- (4-chloro-phenoxy) -propoxyamine and 7.3g of 2- (1-butyryl) -5- (2-ethylmercaptopropyl) -1, 3-cyclohexanedione and 100.0ml of petroleum ether, the temperature was kept constant at 35 ℃ for 6 hours, 100.0ml of saturated saline was added to the system, and the aqueous phase was adjusted to pH 1 or so with 20 wt% hydrochloric acid, and after sufficient stirring, the mixture was separated into layers, the organic phase was washed with saline to neutrality, and the solvent was removed to obtain a yellow viscous liquid, and component C having an optical purity of more than 95% was determined by mass spectrometry, 400M nuclear magnetism and an automatic analyzer.
Calcium dodecyl sulfonate used below was an emulsifier, purchased from Shandong Tiandao; styryl phenol polyoxyethylene ether is used as a dispersant and purchased from Haian petrochemical; the solvent oil is 150# solvent oil which is purchased from Mobil corporation; nonylphenol polyoxyethylene ether is used as a suspending agent and is purchased from Shandong Tiandao company; farm milk 500# is an emulsifier, purchased from Shandong Tiandao company; NP-10 is an emulsifier available from Shandong Tiandao; methyl oleate is a solvent and is purchased from jacai, gaily, inc.
The amounts of the raw materials used in the following examples are in parts by weight unless otherwise specified, and each part by weight represents 1 g.
Example 1: 12.5% by weight of emulsifiable concentrate
Cyhalofop-butyl 10, compound 168 is 2.5, calcium dodecyl sulfonate 6, styrylphenol polyoxyethylene ether 6, and solvent oil to make up to 100.
Adding the components into a stirring kettle, and uniformly stirring to obtain the missible oil.
Comparative example 1: 12.5% by weight of emulsifiable concentrate
10 parts of cyhalofop-butyl, 2.5 parts of clethodim, 6 parts of calcium dodecyl sulfonate, 6 parts of styrylphenol polyoxyethylene ether and solvent oil, wherein the solvent oil is supplemented to 100 parts.
Adding the components into a stirring kettle, and uniformly stirring to obtain the missible oil.
Example 2: 20% by weight aqueous emulsion
Cyhalofop-butyl 10, 10 of compound 168, 6 of calcium dodecyl sulfonate, 6 of styrylphenol polyoxyethylene ether, 3 of nonylphenol polyoxyethylene ether, 20 of solvent oil and water, wherein the balance is 100.
Adding the oil phase substances in the components into the water phase, and shearing by a shearing machine to obtain the aqueous emulsion.
Comparative example 2: 20% by weight aqueous emulsion
Fenoxaprop-p-ethyl 10, 10 of a compound 168, 6 of calcium dodecyl sulfonate, 6 of styrylphenol polyoxyethylene ether, 3 of nonylphenol polyoxyethylene ether, 20 of solvent oil and water, wherein the balance is 100.
And adding the oil phase substances in the composition into the water phase, and shearing by a shearing machine to obtain the aqueous emulsion.
Example 3: 25% by weight of emulsifiable concentrate
Cyhalofop-butyl 20, compound 168 is 5, calcium dodecyl sulfonate 6, styrylphenol polyoxyethylene ether 6, and solvent oil to make up to 100.
Adding the components into a stirring kettle, and uniformly stirring to obtain the missible oil.
Example 4: 8% by weight of an oil suspension
Cyhalofop-butyl 6, compound 168 is 2, agricultural emulsion 500# is 8, NP-10 is 9, methyl oleate is made up to 100.
And adding the components into a shearing kettle for shearing, and grinding in a sand mill to obtain the oil suspending agent.
Example 5: 25 wt% oil suspension
Cyhalofop-butyl 20, compound 168 is 5, Nongru 500# is 8, NP-10 is 9, methyl oleate makes up to 100.
And adding the components into a shearing kettle for shearing, and grinding in a sand mill to obtain the oil suspending agent.
Indoor toxicity assay
Reagent to be tested: cyhalofop-butyl technical (95 wt%), compound 168 technical (95 wt%).
Test targets: barnyard grass (Echinochloa crusgalli (L.)), Euphorbia lathyris (Eurobia lathyris L.), and Digitaria sanguinalis (L.); the crop is rice.
The dosage design of the medicament:
the single dose of cyhalofop-butyl is 150, 300 and 600g a.i./ha; single doses of the cyclohexenone herbicide compound 168 were 37.5, 75, 150g a.i./ha; cyhalofop-butyl and the single cyclohexenone herbicide compound 168 were used in amounts of 150+37.5, 150+75, 150+150, 300+37.5, 300+75, 300+150, 600+37.5, 600+75, 600+150g a.i./ha.
Cyhalofop-butyl and compound 168 were dissolved in acetone, respectively, and diluted with a 0.1 wt% aqueous solution of T-80 to prepare a 5g/L solution. Control treatment 0.1mL of acetone was added and 80mL of 0.1 wt% aqueous T-80 solution was added.
Herbicidal activity test method: a stem and leaf spraying method (NY/T1155.4-2006) is adopted, quantitative soil is filled in a pot with the height of 11cm and the diameter of 9cm to reach the position 3/4 of the pot, 15-20 weed seeds to be tested targets are uniformly sown on the soil surface of the pot, and the pot is covered with fine soil of about 1cm and then placed in a greenhouse (the temperature is 22-28 ℃, the humidity is 97 percent, the same is applied below) for culture. And carrying out stem and leaf spraying treatment when the weeds grow to 3-5 leaf stage, and spraying 1mL of pesticide liquid in each pot. Each treatment was repeated 4 times, and the control was treated without the agent, and the treated test specimens were cultivated in a greenhouse, and the growth of the target weeds was observed periodically, and the results are shown in tables 1 to 6.
The investigation method comprises the following steps: after 30 days of test treatment, the target damage symptoms and growth inhibition condition are visually observed, the fresh weight of the overground part is weighed, and the fresh weight inhibition rate (%) is calculated. Fresh weight inhibition (%) - (control fresh weight-treated fresh weight)/control fresh weight × 100
The combined action evaluation method comprises the following steps: the mode of action of the herbicide combinations was evaluated according to the Gowing method (NY/T1155.7-2006), which is formulated as: e0X + yx (100-X)/100, wherein X is the fresh weight inhibition ratio of the target weed when cyhalofop-butyl is used alone; y is the fresh weight inhibition rate of the target weed when the cyclohexenone herbicide is used alone; e0The herbicide is a theoretical prevention effect of a target when cyhalofop-butyl and cyclohexenone herbicides are mixed; and E is the actual prevention effect of the target when the cyhalofop-butyl and the cyclohexenone herbicides are mixed.
Evaluation criteria: when E-E0>When 10% is expressed as a synergistic effect, when E-E0Within. + -. 10% is additive when E-E0<Antagonism was indicated at-10%.
Table 1: cyhalofop-butyl and compound 168 treatment pairsBarnyard grassResults of indoor toxicity measurement
Table 2: cyhalofop-butyl and compound 168 treatment pairsAll-grass of Japanese stephaniaResults of indoor toxicity measurement
Table 3: cyhalofop-butyl and compound 168 treatment pairsTang style foodResults of indoor toxicity measurement
As can be seen from the indoor toxicity measurement results in tables 1, 2 and 3, the combination of cyhalofop-butyl and compound 168 has synergistic effect on barnyard grass, moleplant seed and large crabgrass.
Determination of safety indoor toxicity of rice
Two leaves and one heart period of rice
Compound 168 was set at 5 doses: 75. 150, 300, 450, 600g.a.i./ha
Compound 168 plus cyhalofop-butyl was set at 6 doses: 75+300, 150+300, 300+300, 450+300, 600+300g.a.i./ha
The method for testing the safety of the rice comprises the following steps: adopting a stem leaf spraying method (NY/T1155.4-2006): quantitative soil is filled in a pot with the height of 11cm and the diameter of 9cm to 3/4 parts of the pot, rice of each variety of the target to be tested is sowed on the soil surface of the pot, and the pot is covered with fine soil about 1cm and then is cultured in a greenhouse. When the rice grows to 2-leaf stage, carrying out stem and leaf spraying treatment, and spraying 1mL of liquid in each pot. Repeating the treatment for 4 times, taking the treatment without the medicament as a control, culturing the treated test material in a greenhouse, and regularly observing the growth condition of the rice.
The investigation method comprises the following steps: after the test treatment for 20 days, the target damage symptoms and growth inhibition conditions are visually observed, the plant height of the rice is measured, and the plant height inhibition rate (%) is calculated.
The inhibition rate (%) of the plant height is equal to (control plant height-treated plant height)/control plant height is multiplied by 100, and the DPS statistical software is used for carrying out regression analysis on the logarithm value of the medicament dosage and the inhibition rate of the plant height of the rice, and calculating the correlation coefficient and ED10(amount of herbicide used to inhibit rice plant height 10%) and 95% confidence intervals, the results are shown in tables 4-5, respectively.
Table 4: indoor toxicity assay (plant height inhibition rate) of compound 168 on rice by itself
Table 5: toxicity determination result of compound 168+ cyhalofop-butyl (20g.a.i/mu) on inhibition of plant heights of different rice varieties
According to the indoor bioassay results, the compound 168 can generate a certain whitening phenomenon on rice when being used alone, and the growth of the rice is inhibited to a certain extent; the compound 168 is compounded with cyhalofop-butyl, so that the safety of the compound to rice is improved by more than 1 time on the premise of adding and synergizing the effect on weeds, the safety is obviously improved, and the growth of the rice is not influenced under the active dose of the herbicide.
And (3) field efficacy test:
and (3) test crops: direct seeding rice
The administration period is as follows: 15 days after sowing, 3 leaves and 1 heart of rice and 3-4 leaves of weeds
And (3) test treatment:
10 wt% cyhalofop-butyl emulsifiable concentrate, 3000, 6000 mL/ha;
10% by weight of compound 168 emulsifiable concentrate, 750, 1500 mL/ha;
example 1 agents: 12.5 wt% of missible oil, 3000, 6000 mL/ha;
example 2 agents: 20 wt% aqueous emulsion, 750, 1500 mL/ha;
example 3 agents: 25 wt% of emulsifiable concentrate, 1500, 3000 mL/ha;
example 4 agents: 8 wt% of oil suspending agent, 3000, 6000 mL/ha;
example 5 agents: 25 wt% oil suspending agent, 1500, 3000 mL/ha;
comparative example 1 agent: 12.5 wt% of missible oil, 3000, 6000 mL/ha;
comparative example 2 agent: 20 wt% aqueous emulsion, 750, 1500 mL/ha;
selecting the heavy-weight land with the length of 20m for barnyard grass, moleplant seed, large crabgrass and paspalum distichum2Repeating each treatment for 3 times in a small area, spraying stems and leaves 15 days after direct seeding, watering 48 hours after application, and keeping water for 5-7 days.
And observing the treatment area and the control area 30 days after treatment, counting the number of weeds and calculating the plant control effect of the weeds in the treatment area.
And observing the treatment area and the control area 30 days after treatment, and counting fresh weight control effect. And the safety of the drug to rice was evaluated according to the evaluation criteria visual method of table 7.
The control effect and safety of each agent on weeds are shown in table 6, and the control effect in table 6 is represented by fresh weight inhibition ratio P (%).
Table 6: the control effect and safety of each example and comparative example on weeds
Table 7: standard for evaluating safety of medicine by visual inspection method
As can be seen from the results in Table 6, the mixture of cyhalofop-butyl and the compound 168 has good control effect on gramineous weeds in paddy fields, and the synergistic effect between the agents is obvious.
The field pesticide effect result shows that when the compound 168 is used alone, the rice can generate pesticide damage, which is mainly reflected in that whitening stripes appear and the plant height is dwarfed to a certain extent compared with a control.
The results of the comparative example show that cyhalofop-butyl has obvious phytotoxicity on rice when being compounded with a common cyclohexenone herbicide clethodim; moreover, when the similar compound of cyhalofop-butyl, fenoxaprop-p-ethyl, is compounded with the compound 168, the pesticide has obvious phytotoxicity to rice. However, the inventor of the invention discovers through creative research that when the cyhalofop-butyl is compounded with the compound 168, the weeding spectrum of the cyhalofop-butyl in the paddy field is expanded, and the cyhalofop-butyl has obvious synergistic effect, is more important, is safe to paddy and has practical application value.
The preferred embodiments of the present invention have been described above in detail, but the present invention is not limited thereto. Within the scope of the technical idea of the invention, many simple modifications can be made to the technical solution of the invention, including combinations of various technical features in any other suitable way, and these simple modifications and combinations should also be regarded as the disclosure of the invention, and all fall within the scope of the invention.
Claims (10)
1. A pesticide composition comprises a component A and a component B with effective weeding amount, wherein the content weight ratio of the component A to the component B is 1: (0.5-70), wherein the component A is a compound 168 shown in a formula (I), and the component B is cyhalofop-butyl shown in a formula (II); optionally, the composition also contains a component C shown in a formula (III);
2. the composition according to claim 1, wherein the content weight ratio of the cyclohexenone herbicide to the cyhalofop-butyl is 1: (1-60); preferably 1: (1.02-50).
3. The composition of claim 1 or 2, wherein the weight ratio of component a to component C is 1: (0.1-1).
4. Use of the pesticidal composition of any one of claims 1 to 3 for controlling weeds.
5. Use according to claim 4, wherein the weeds are grasses; preferably, the first and second electrodes are formed of a metal,
the grass family weeds are one or more than two of moleplant seed, large crabgrass, barnyard grass, rice grass, green bristlegrass, reed, paspalum distichum and goosegrass.
6. A herbicide, which consists of an active ingredient and an auxiliary material, wherein the active ingredient is the pesticide composition as claimed in any one of claims 1 to 3.
7. The herbicide as claimed in claim 6, wherein the active ingredient is contained in an amount of 5 to 100% by weight, based on the total weight of the herbicide; preferably 15 to 98 wt%.
8. A herbicide as claimed in claim 6, wherein the adjuvant is at least one of an emulsifier, a dispersant, a wetting agent, a spreader, a stabilizer, an antifoaming agent, a synergist, a penetrant, a binder, a safener, a carrier and a filler.
9. The herbicide according to claim 6, wherein the formulation of the herbicide is at least one selected from the group consisting of wettable powder, soluble powder, emulsifiable concentrate, water suspension, dispersible oil suspension, aqueous emulsion, microemulsion and water dispersible granule.
10. The herbicide as claimed in claim 6, wherein the herbicide is in the form of emulsifiable concentrate, and the content of the active ingredient is 1-60 wt% based on the total weight of the herbicide; preferably, the first and second electrodes are formed of a metal,
the herbicide is in the form of an aqueous emulsion, and the content of the active ingredients is 1-50 wt% based on the total weight of the herbicide; preferably, the first and second electrodes are formed of a metal,
the herbicide is an oil suspending agent, and the content of the active ingredients is 1-40 wt% based on the total weight of the herbicide.
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| CN114591230A (en) * | 2022-03-07 | 2022-06-07 | 沈阳万菱生物技术有限公司 | Cyclohexenone compound, application thereof and pesticide herbicide |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW232646B (en) * | 1992-02-13 | 1994-10-21 | Basf Ag | |
| CN107094764A (en) * | 2017-06-23 | 2017-08-29 | 江苏富田农化有限公司 | The Herbicidal combinations and its application in agent for removing grass in paddy field of the ketone of sulphur containing ring and cyhalofop-butyl |
-
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW232646B (en) * | 1992-02-13 | 1994-10-21 | Basf Ag | |
| CN107094764A (en) * | 2017-06-23 | 2017-08-29 | 江苏富田农化有限公司 | The Herbicidal combinations and its application in agent for removing grass in paddy field of the ketone of sulphur containing ring and cyhalofop-butyl |
Non-Patent Citations (3)
| Title |
|---|
| 夏海生: "7种除草剂对直播水稻田稗草的防除效果研究", 《现代农业科技》 * |
| 山东先达农化股份有限公司: "12.5%苯丙•氰氟草酯乳油", 《山东先达农化股份有限公司企业标准》 * |
| 张佩 等: "20%氰氟草酯和10%氰氟草酯防除水稻田禾本科杂草药效比较试验", 《上海农业科技》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114591230A (en) * | 2022-03-07 | 2022-06-07 | 沈阳万菱生物技术有限公司 | Cyclohexenone compound, application thereof and pesticide herbicide |
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