CN112648163A

CN112648163A - High-pressure advection infusion pump of liquid chromatograph

Info

Publication number: CN112648163A
Application number: CN202011316696.0A
Authority: CN
Inventors: 章志尧
Original assignee: Jiangsu Tongji Analytical Instrument Co ltd
Current assignee: Jiangsu Tongji Analytical Instrument Co ltd
Priority date: 2020-11-23
Filing date: 2020-11-23
Publication date: 2021-04-13

Abstract

The invention discloses a high-pressure advection infusion pump of a liquid chromatograph, belonging to the technical field of high-pressure advection infusion pumps, and particularly relating to a high-pressure advection infusion pump of a liquid chromatograph, which comprises an infusion pump body, wherein the infusion pump body comprises a pump body and a pump head, the pump head is arranged on the right side of the pump body, the middle part of the pump head is provided with a piston moving cavity, a piston is connected in the piston moving cavity in a sliding way, a liquid inlet one-way valve is arranged below the right side of the pump head, the piston moving cavity is communicated with the liquid inlet one-way valve, the lower side of the liquid inlet one-way valve is fixedly connected with a liquid inlet pipe, the upper side of the right side of the pump head is provided with a liquid outlet one-way valve, the upper side of the liquid outlet one-way valve is fixedly connected with a liquid outlet, the fixed rod is rotatably connected with the bearing, so that the generated friction force and abrasion are small, and the service life is prolonged.

Description

High-pressure advection infusion pump of liquid chromatograph

Technical Field

The invention relates to the technical field of high-pressure advection infusion pumps, in particular to a high-pressure advection infusion pump of a liquid chromatograph.

Background

The high-pressure infusion pump is an important unit component in an analysis system of the liquid chromatograph and is used for inputting a mobile phase and a sample into the chromatographic column and the detector, so that the reliability of the whole instrument and an analysis result is directly influenced by the performance of an analysis of the sample. There are two types of high-pressure infusion pumps for liquid chromatographs, commonly referred to as constant flow pumps and constant pressure pumps. The constant flow pump stabilizes the output liquid flow; and the constant pressure pump stabilizes the output liquid pressure. The constant flow pump is provided with a reciprocating pump, an injection pump and the like; the constant pressure pump comprises a pneumatic amplifying pump and the like.

When the existing high-pressure advection infusion pump for the liquid chromatograph is used, the cam drives the slide block to move through the connecting rod, so that the friction force is large, the abrasion is easy to generate, and the stability for conveying a mobile phase and a sample is poor.

Disclosure of Invention

The invention aims to provide a high-pressure advection infusion pump for a liquid chromatograph, which aims to solve the problems that in the use process of the high-pressure advection infusion pump for the liquid chromatograph, the friction force is large, the abrasion is easy to generate, and the stability for conveying a mobile phase and a sample is poor in the process that a cam drives a sliding block to move through a connecting rod.

In order to achieve the purpose, the invention provides the following technical scheme: a high-pressure advection infusion pump of a liquid chromatograph comprises an infusion pump body, wherein the infusion pump body comprises a pump body and a pump head, the pump head is arranged on the right side of the pump body, a piston moving cavity is arranged in the middle of the pump head, a piston is connected in the piston moving cavity in a sliding manner, a liquid inlet one-way valve is arranged below the right side of the pump head, the piston moving cavity is communicated with the liquid outlet one-way valve, a liquid outlet pipe is fixedly connected on the upper side of the liquid outlet one-way valve, a liquid flow sensor is arranged on a pipeline of the liquid outlet pipe, a plunger rod is fixedly connected in the middle of the left side of the piston, the pump body is provided with a fixed plate, a sliding groove is arranged in the front side of the fixed plate, a sliding block is connected in the sliding groove, and the, the utility model discloses a pump body, including pump body, motor, liquid flow sensor, motor output shaft, bearing hole, bearing, dead lever, bearing and jump ring, the motor is installed at pump body left side rear, the speed reducer is installed to the motor front side, motor output shaft is located the speed reducer, the transmission shaft is installed to the speed reducer front side, transmission shaft front end fixedly connected with cam, the equal fixedly connected with dead lever in cam and slider front side, install the connecting rod between cam and the slider, the dead lever left and right sides has all seted up the dead hole, install the bearing in the dead hole, the dead lever rear side is provided with keeps off the shoulder, the bearing is located keeps off shoulder front side, the dead lever passes through the bearing and is connected with the connecting rod rotation, the dead lever front side is seted up the jump ring groove, install the jump ring.

Preferably, the outer wall of the piston is provided with a sealing ring.

Preferably, the number of the sealing rings is two, and the two sealing rings are respectively positioned at the left side and the right side of the piston.

Preferably, the feed liquor check valve includes first valve body, first spring, first one-way control chamber, first intercommunication chamber and first ball sealer, first intercommunication chamber has been seted up at first valve body middle part, first intercommunication chamber upside is provided with first one-way control chamber, first one-way control chamber downside is big-end-up's toper, the first spring of first one-way control chamber upper end fixedly connected with, the first ball sealer of first spring lower extreme fixedly connected with, first intercommunication chamber lower extreme and feed liquor pipe fixed connection.

Preferably, the first sealing ball presses a tapered wall on the lower side of the first one-way control chamber to form a seal under the elastic force of the first spring.

Preferably, the liquid outlet one-way valve comprises a second valve body, a second spring, a second one-way control cavity, a second communication cavity and a second sealing ball, the second communication cavity is formed in the middle of the second valve body, the second one-way control cavity is arranged on the lower side of the second communication cavity, the lower side of the second one-way control cavity is in a conical shape with a large top and a small bottom, the second spring is fixedly connected to the upper end of the second one-way control cavity, the second sealing ball is fixedly connected to the lower end of the second spring, and the upper end of the second communication cavity is fixedly connected with the liquid outlet pipe.

Preferably, the second sealing ball presses the tapered wall on the lower side of the second one-way control chamber to form a seal under the elastic force of the second spring.

Preferably, the motor is a servo motor.

Preferably, a blocking cover is connected to the front side of the bearing hole through a screw.

Compared with the prior art, the invention has the beneficial effects that:

1) through the arrangement of the bearing, the cam drives the connecting rod to move through the fixed rod and the bearing, the connecting rod drives the sliding block to move through the fixed rod and the bearing, the fixed rod is rotatably connected with the bearing, the generated friction force and abrasion are small, and the service life is prolonged;

2) the infusion pump body can convey liquid at high pressure by the left-right reciprocating movement of the piston, the real-time flow of the liquid is detected by the liquid flow sensor in the liquid conveying process, the flow signal is transmitted to the control box, and the control box controls the rotating speed of the motor, so that the moving speed of the piston is controlled, and the infusion pump body can carry out advection infusion;

3) through the setting of keeping off shoulder and jump ring, improve the stability of junction between cam, connecting rod and the dead lever.

Drawings

FIG. 1 is a schematic structural view of the present invention;

FIG. 2 is a left side view of the cam of the present invention;

FIG. 3 is an enlarged view of FIG. 2A of the present invention;

FIG. 4 is a schematic view of the liquid outlet check valve of the present invention;

fig. 5 is a schematic structural diagram of the liquid inlet check valve.

In the figure: 1 infusion pump body, 2 pump heads, 3 pump bodies, 4 liquid outlet one-way valves, 5 liquid inlet one-way valves, 6 pistons, 7 sealing rings, 8 plunger rods, 9 fixing plates, 10 sliding grooves, 11 sliding blocks, 12 control boxes, 13 cams, 14 connecting rods, 15 motors, 16 speed reducers, 17 transmission shafts, 18 fixing rods, 19 bearing holes, 20 bearings, 21 blocking covers, 22 blocking shoulders, 23 clamping spring grooves, 24 clamping springs, 25 second springs, 26 second valve bodies, 27 second sealing balls, 28 liquid flow sensors, 29 liquid outlet pipes, 30 second one-way control cavities, 31 first one-way control cavities, 32 first springs, 33 first sealing balls, 34 first communication cavities, 35 piston moving cavities, 36 second communication cavities, 37 liquid inlet pipes and 38 first valve bodies.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

In the description of the present invention, it should be noted that the terms "upper", "lower", "inner", "outer", "top/bottom", and the like indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the referred device or element must have a specific orientation, be constructed in a specific orientation, and be operated, and thus should not be construed as limiting the present invention. Furthermore, the terms "first" and "second" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.

In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "disposed," "sleeved/connected," "connected," and the like are to be construed broadly, e.g., "connected," which may be fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.

Example (b):

referring to fig. 1-5, the present invention provides a technical solution: the utility model provides a liquid chromatograph high pressure advection transfer pump, includes transfer pump body 1, transfer pump body 1 includes pump body 3 and pump head 2, pump head 2 is installed on pump body 3 right side, pump head 2 middle part has been seted up the piston and has been removed chamber 35, sliding connection has piston 6 in the piston removes chamber 35, and piston 6 can remove about in piston removal chamber 35, feed liquor check valve 5 is installed to pump head 2 right side below, piston removal chamber 35 and feed liquor check valve 5 intercommunication, 5 downside fixedly connected with feed liquor pipe 37 of feed liquor check valve, liquid chromatograph is arranged in to feed liquor pipe 37 lower extreme, absorbs detection liquid, go out liquid check valve 4 is installed to pump head 2 right side top, piston removal chamber 35 and play liquid check valve 4 intercommunication, go out 4 upside fixedly connected with drain pipe 29 of liquid check valve, detector intercommunication in drain pipe 29 upper end and the liquid chromatograph, a liquid flow sensor 28 is mounted on a pipeline of the liquid outlet pipe 29, a plug rod 8 is fixedly connected to the middle of the left side of the piston 6, the pump body 3 is provided with a fixed plate 9, a chute 10 is formed in the front side of the fixed plate 9, a sliding block 11 is connected in the chute 10 in a sliding manner, the sliding block 11 can slide left and right in the chute 10, the left end of the plug rod 8 is connected with the right end of the sliding block 11 through a bolt, a motor 15 is mounted at the rear of the left side of the pump body 3, a speed reducer 16 is mounted on the front side of the motor 15, an output shaft of the motor 15 is located in the speed reducer 16, a transmission shaft 17 is mounted on the front side of the speed reducer 16, a cam 13 is fixedly connected to the front end of the transmission shaft 17, fixed rods 18 are fixedly connected to the front sides of the cam 13 and, install bearing 20 in the

dead lever

19, 18 rear sides of dead lever are provided with and keep off shoulder 22, carry on spacingly, bearing 20 is located and keeps off shoulder 22 front side, dead lever 18 passes through bearing 20 and is connected with connecting rod 14 rotation, 18 front sides of dead lever are opened and are equipped with jump ring groove 23, install jump ring 24 in jump ring groove 23 for it is spacing, prevent that dead lever 18 from breaking away from bearing 20, also can prevent that bearing 20 from loosening and taking off, jump ring 24 is located the bearing 20 front side, 3 upsides of pump body are provided with control box 12, motor 15, liquid flow sensor 28 all are connected with control box 12 electricity.

And a sealing ring 7 is arranged on the outer wall of the piston 6, so that the sealing property is improved.

The number of the sealing rings 7 is two, and the two sealing rings 7 are respectively positioned at the left side and the right side of the piston 6.

Feed liquor check valve 5 includes first valve body 38, first spring 32, first one-way control chamber 31, first communication chamber 34 and first ball sealer 33, first communication chamber 34 has been seted up at 38 middle parts of first valve body, first communication chamber 34 upside is provided with first one-way control chamber 31, first one-way control chamber 31 downside is big-end-up's toper, first one-way control chamber 31 upper end fixedly connected with first spring 32, first spring 32 lower extreme fixedly connected with first ball sealer 33, first communication chamber 34 lower extreme and feed liquor pipe 37 fixed connection, during the feed liquor, piston 6 removes left, and the piston on 6 right sides removes chamber 35 volume grow, and pressure reduces, makes first ball sealer 33 upwards remove first spring compressor 32, removes the sealed of first communication chamber 34, makes liquid can get into piston removal chamber 35 smoothly.

Under the elastic force of the first spring 32, the first sealing ball 33 presses the tapered wall on the lower side of the first unidirectional control chamber 31 to form a seal.

The liquid outlet one-way valve 4 comprises a second valve body 26, a second spring 25, a second one-way control cavity 30, a second communication cavity 36 and a second sealing ball 27, the second communication cavity 36 is formed in the middle of the second valve body 26, the second one-way control cavity 30 is arranged on the lower side of the second communication cavity 36, the lower side of the second one-way control cavity 30 is in a conical shape with a large upper part and a small lower part, the second spring 25 is fixedly connected to the upper end of the second one-way control cavity 30, the second sealing ball 27 is fixedly connected to the lower end of the second spring 25, the upper end of the second communication cavity 36 is fixedly connected with the liquid outlet pipe 29, when liquid is discharged, the piston 6 moves rightwards, the volume of the piston moving cavity 35 on the right side of the piston 6 is reduced, the pressure is increased, the second sealing ball 27 moves upwards to compress the second spring 25, the sealing of the second one-way control cavity 30 is released, and liquid in the piston, the discharge from the second communication chamber 36 can be smoothly performed.

Under the elastic force of the second spring 25, the second sealing ball 27 presses the tapered wall on the lower side of the second one-way control chamber 30 to form a seal.

The motor 15 is a servo motor and moves accurately.

A stop cover 21 is connected to the front side of the bearing hole 19 through a screw.

The working principle is as follows: the fixed rod 18 drives the transmission shaft 17 to rotate through the speed reducer 16, the transmission shaft 17 drives the cam 13 to rotate, when the cam 13 rotates, the slide block 11 is driven by the connecting rod 14 to reciprocate left and right, the slide block 11 drives the piston 6 to reciprocate left and right through the plug rod 8, when liquid is fed, the piston 6 moves left, the volume of the piston moving cavity 35 on the right side of the piston 6 is increased, the pressure is reduced, the first sealing ball 33 moves upwards to compress the first spring 32 to remove the sealing of the first communication cavity 34, so that the liquid can smoothly enter the piston moving cavity 35, at the moment, the second sealing ball 27 forms the sealing through extruding the conical wall on the lower side of the second one-way control cavity 30 through the elastic action of the second spring 25, when liquid is discharged, the piston 6 moves rightwards, the volume of the piston moving cavity 35 on the right side of the piston 6 is reduced, the pressure is increased, so that the second sealing ball 27 moves, the liquid in the piston moving cavity 35 can be smoothly discharged from the second communicating cavity 36 under the pushing of the piston 6, at the moment, under the elastic force action of the first spring 32, the first sealing ball 33 forms a seal by extruding the conical wall on the lower side of the first one-way control cavity 31, the liquid in the second communicating cavity 36 enters a detector in the liquid chromatograph through the liquid outlet pipe 29, the real-time flow of the liquid is detected through the liquid flow sensor 28 in the liquid conveying process, the flow signal is transmitted to the control box 12, the control box 12 controls the rotating speed of the motor 15, so that the moving speed of the piston 6 is controlled, and the infusion pump body 1 can carry out advection infusion.

While there have been shown and described the fundamental principles and essential features of the invention and advantages thereof, it will be apparent to those skilled in the art that the invention is not limited to the details of the foregoing exemplary embodiments, but is capable of other specific forms without departing from the spirit or essential characteristics thereof; the present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein, and any reference signs in the claims are not intended to be construed as limiting the claim concerned.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims

1. The utility model provides a liquid chromatograph high pressure advection transfer pump, includes transfer pump body (1), its characterized in that: the infusion pump comprises an infusion pump body (1) and a pump head (2), wherein the pump head (2) is arranged on the right side of the pump body (3), the middle part of the pump head (2) is provided with a piston moving cavity (35), the piston moving cavity (35) is internally provided with a piston (6) in a sliding connection manner, a liquid inlet one-way valve (5) is arranged below the right side of the pump head (2), the piston moving cavity (35) is communicated with the liquid inlet one-way valve (5), the liquid inlet one-way valve (5) is fixedly connected with a liquid inlet pipe (37) on the lower side of the liquid inlet one-way valve (5), a liquid outlet one-way valve (4) is arranged above the right side of the pump head (2), the piston moving cavity (35) is communicated with the liquid outlet one-way valve (4), the upper side of the liquid outlet one-way valve (4) is fixedly connected with a liquid outlet pipe (29), a liquid, the pump body (3) is provided with a fixed plate (9), a sliding groove (10) is formed in the front side of the fixed plate (9), a sliding block (11) is connected to the sliding groove (10) in a sliding mode, the left end of a plug rod (8) is connected with the right end of the sliding block (11) through a bolt, a motor (15) is installed on the rear side of the left side of the pump body (3), a speed reducer (16) is installed on the front side of the motor (15), an output shaft of the motor (15) is located in the speed reducer (16), a transmission shaft (17) is installed on the front side of the speed reducer (16), a cam (13) is fixedly connected to the front side of the transmission shaft (17), a fixed rod (18) is fixedly connected to the front sides of the cam (13) and the sliding block (11), a connecting rod (14) is installed between the cam (13) and the sliding block (11), bearing holes (19), dead lever (18) rear side is provided with keeps off shoulder (22), bearing (20) are located and keep off shoulder (22) front side, dead lever (18) are rotated with connecting rod (14) through bearing (20) and are connected, dead lever (18) front side is opened and is equipped with jump ring groove (23), install jump ring (24) in jump ring groove (23), jump ring (24) are located bearing (20) front side, pump body (3) upside is provided with control box (12), motor (15), liquid flow sensor (28) all are connected with control box (12) electricity.

2. The high-pressure advection infusion pump of the liquid chromatograph of claim 1, wherein: and a sealing ring (7) is arranged on the outer wall of the piston (6).

3. The high-pressure advection infusion pump of the liquid chromatograph of claim 2, wherein: the number of the sealing rings (7) is two, and the two sealing rings (7) are respectively positioned at the left side and the right side of the piston (6).

4. The high-pressure advection infusion pump of the liquid chromatograph of claim 1, wherein: feed liquor check valve (5) include first valve body (38), first spring (32), first one-way control chamber (31), first intercommunication chamber (34) and first ball sealer (33), first intercommunication chamber (34) have been seted up at first valve body (38) middle part, first intercommunication chamber (34) upside is provided with first one-way control chamber (31), first one-way control chamber (31) downside is big-end-up's toper, first one-way control chamber (31) upper end fixedly connected with first spring (32), first ball sealer (33) of first spring (32) lower extreme fixedly connected with, first intercommunication chamber (34) lower extreme and feed liquor pipe (37) fixed connection.

5. The high-pressure advection infusion pump of liquid chromatograph of claim 4, characterized in that: under the action of the elastic force of the first spring (32), the first sealing ball (33) presses the conical wall on the lower side of the first one-way control cavity (31) to form a seal.

6. The high-pressure advection infusion pump of the liquid chromatograph of claim 1, wherein: go out liquid check valve (4) and include second valve body (26), second spring (25), second one-way control chamber (30), second intercommunication chamber (36) and second ball sealer (27), second intercommunication chamber (36) have been seted up at second valve body (26) middle part, second intercommunication chamber (36) downside is provided with second one-way control chamber (30), second one-way control chamber (30) downside is big-end-up's toper, second one-way control chamber (30) upper end fixedly connected with second spring (25), second spring (25) lower extreme fixedly connected with second ball sealer (27), second intercommunication chamber (36) upper end and drain pipe (29) fixed connection.

7. The high-pressure advection infusion pump of liquid chromatograph of claim 6, characterized in that: under the action of the elastic force of the second spring (25), the second sealing ball (27) presses the conical wall on the lower side of the second one-way control cavity (30) to form a seal.

8. The high-pressure advection infusion pump of the liquid chromatograph of claim 1, wherein: the motor (15) is a servo motor.

9. The high-pressure advection infusion pump of the liquid chromatograph of claim 1, wherein: the front side of the bearing hole (19) is connected with a blocking cover (21) through a screw.