CN112587782A - Medical guide wire - Google Patents

Medical guide wire Download PDF

Info

Publication number
CN112587782A
CN112587782A CN202011438372.4A CN202011438372A CN112587782A CN 112587782 A CN112587782 A CN 112587782A CN 202011438372 A CN202011438372 A CN 202011438372A CN 112587782 A CN112587782 A CN 112587782A
Authority
CN
China
Prior art keywords
section
guide wire
cutting
guidewire
core wire
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN202011438372.4A
Other languages
Chinese (zh)
Other versions
CN112587782B (en
Inventor
李涛
田梦云
陈万祺
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shanghai Puhui Medical Equipment Co ltd
Original Assignee
Shanghai Puhui Medical Equipment Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Puhui Medical Equipment Co ltd filed Critical Shanghai Puhui Medical Equipment Co ltd
Priority to CN202011438372.4A priority Critical patent/CN112587782B/en
Publication of CN112587782A publication Critical patent/CN112587782A/en
Application granted granted Critical
Publication of CN112587782B publication Critical patent/CN112587782B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09—Guide wires
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/02—Inorganic materials
    • A61L31/022—Metals or alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/048—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09—Guide wires
    • A61M2025/09133—Guide wires having specific material compositions or coatings; Materials with specific mechanical behaviours, e.g. stiffness, strength to transmit torque
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09—Guide wires
    • A61M2025/09175—Guide wires having specific characteristics at the distal tip
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09—Guide wires
    • A61M2025/09175—Guide wires having specific characteristics at the distal tip
    • A61M2025/09183—Guide wires having specific characteristics at the distal tip having tools at the distal tip

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Surgical Instruments (AREA)

Abstract

The invention discloses a medical guide wire, and belongs to the technical field of machinery. The invention provides a guide wire, which comprises a near-end isodiametric core wire section and a far-end reducing core wire section, wherein the reducing core wire section comprises a near-end cutting section and a far-end tip, a plurality of pairs of recesses formed by cutting are uniformly distributed on the cutting section along the axial direction, the two recesses in the same pair are symmetrically arranged relative to the axis of the reducing core wire section, the adjacent two pairs of recesses are arranged in a staggered manner, and the cutting section is arranged, so that the guide wire has stable supporting force on the whole and has better torque transmission capacity, therefore, the guide wire has the capacity of passing through tortuous blood vessels and is not easy to damage the blood vessels. The invention provides a guide wire, wherein a tip end of the guide wire is provided with a tip section and is sleeved with a spring, an elastic sheath is wrapped outside the spring, and the tip end and the elastic sheath are arranged to ensure that the part of the guide wire, preferably contacted with the inner wall of a blood vessel, is soft enough, so that the guide wire is not easy to damage the blood vessel.

Description

Medical guide wire
Technical Field
The invention relates to a medical guide wire, and belongs to the technical field of machinery.
Background
A Guide Wire (Guide Wire), also known as a Guide Wire or Guide Wire, is one of the main tools for percutaneous cannulation. The guide wire plays a role in guiding and supporting the catheter, helps the catheter to enter blood vessels and other cavities, and guides the catheter to smoothly reach a lesion. In catheter treatment procedures, the same importance is placed on catheters.
Because of the in vivo procedures involved, there are high clinical requirements for guidewire safety. However, the conventional guide wires are easy to damage human organs or tissues such as the inner wall of a blood vessel. The main reason is that the existing partial medical guide wire has high hardness and insufficient softness of the head end, is not easy to adjust the angle when passing through tortuous human organs or tissues such as the inner wall of a blood vessel, cannot smoothly pass through the tortuous human organs or tissues such as the inner wall of the blood vessel, and is easy to scratch the tortuous human organs or tissues such as the inner wall of the blood vessel; the other part of the guide wire has too soft head end, insufficient supporting force and poor torque transmission capability, and can not pass through tortuous human organs or tissues such as the inner wall of a blood vessel.
Therefore, it is urgently needed to design a medical guide wire which is soft, has good supporting force and good torque transmission capacity.
Disclosure of Invention
[ problem ] to
The invention aims to provide a medical guide wire which is soft, good in supporting force and good in torque transmission capacity.
[ solution ]
In order to solve the technical problem, the invention provides a guide wire, which comprises a proximal isodiametric core wire section 1 and a distal reducing core wire section 2; the reducing core wire section 2 comprises a cutting section 3 at the near end and a tip 4 at the far end; a plurality of pairs of cut depressions 5 are uniformly distributed on the cutting section 3 along the axial direction, two depressions 5 in the same pair are symmetrically arranged about the axis of the reducing core wire section 2, and two adjacent pairs of depressions 5 are arranged in a staggered manner.
In one embodiment of the invention, the tip 4 is sleeved with a spring 6; an elastic sheath 7 is wrapped outside the spring 6.
In one embodiment of the invention, the depth of the depression 5 tapers from the proximal end to the distal end.
In one embodiment of the invention, two adjacent pairs of recesses 5 are staggered by 180 °.
In one embodiment of the present invention, the cutting segment 3 is a non-cutting portion and a cutting portion distributed with a recess 5 from the proximal end to the distal end; the cutting parts are respectively an A section, a B section, a C section and a D section from the near end to the far end, and the cutting conicity of the concave 5 on the A section, the B section, the C section and the D section is respectively 0.02 degrees, 0.01 degrees, 0.02 degrees and 0.01 degrees.
In one embodiment of the present invention, the lengths of the sections a, B, C and D are 10cm, 10cm and 10cm, respectively.
In one embodiment of the invention, the length of the non-cutting portion is 10 cm.
In one embodiment of the invention, the cross-section of the recess 5 is annular.
In one embodiment of the invention, the tip 4 is a straight section 8 and a cut-off sharpened section 9 from the distal end to the proximal end, respectively, and the diameter of the sharpened section 9 is gradually reduced from the proximal end to the distal end.
In one embodiment of the invention, the grinding taper of the tapering section 9 is 0.03 °.
In one embodiment of the invention, the straight section 8 has an outer diameter of 0.03mm and a length of 10 cm.
In one embodiment of the invention, the maximum outer diameter of the tapered section 8 is 0.05mm, the minimum diameter is 0.03mm, and the length is 20 cm.
In one embodiment of the invention, the surface of the isodiametric core wire section 1 is provided with a hydrophobic coating.
In one embodiment of the invention, the thickness of the hydrophobic coating on the surface of the isodiametric core wire section 1 is 0.004-0.010 mm.
In one embodiment of the invention, the hydrophobic coating on the surface of the isodiametric core wire segment 1 is a green PTFE hydrophobic coating.
In one embodiment of the invention, the material of the equal-diameter core wire section 1 is SS304 stainless steel.
In one embodiment of the invention, the constant diameter core wire section 1 has an outer diameter of 0.35mm and a length of 100 cm.
In one embodiment of the invention, the surface of the reducing core wire section 2 is provided with a hydrophilic coating.
In one embodiment of the present invention, the hydrophilic coating on the surface of the reducing core wire section 2 is a PVP polyvinylpyrrolidone hydrophilic coating.
In one embodiment of the invention, the thickness of the hydrophilic coating on the surface of the reducing core wire section 2 is 0.004-0.010 mm.
In one embodiment of the invention, the material of the variable diameter core wire section 2 is nickel titanium alloy.
In one embodiment of the invention, the reducing core wire section 2 has an outer diameter of 0.35mm and a length of 80 cm.
In one embodiment of the invention, the equal-diameter core wire section 1 and the reducing core wire section 2 are connected by welding, and the connection firmness of the equal-diameter core wire section 1 and the reducing core wire section 2 is not lower than 10N.
In one embodiment of the invention, the tip 4 is a nickel titanium alloy.
In one embodiment of the invention, the material of the spring 6 is a platinum-nickel alloy visible under radiation.
In one embodiment of the present invention, the platinum-nickel alloy is a platinum-nickel alloy having a Pt content of 90% and a Ni content of 10%.
In one embodiment of the invention, the spring 6 is welded or light-fastened to the tip.
In one embodiment of the invention, the spring 6 has an outer diameter of 0.24mm, an inner diameter of 0.18mm and a length of 30 cm.
In one embodiment of the invention, the surface of the elastic sheath 7 is provided with a hydrophilic coating.
In one embodiment of the present invention, the hydrophilic coating on the surface of the elastic sheath 7 is a PVP polyvinylpyrrolidone hydrophilic coating.
In one embodiment of the invention, the thickness of the hydrophilic coating on the surface of the elastic sheath 7 is 0.004-0.010 mm.
In one embodiment of the present invention, the material of the elastic sheath 7 is a tungsten-containing thermoplastic polymer material.
In one embodiment of the present invention, the content of tungsten in the tungsten-containing thermoplastic polymer material is 40 ± 2%.
In one embodiment of the present invention, the thermoplastic polymer material is one or more of polyurethane, polyethylene or rubber.
In one embodiment of the invention, the elastic sheath 7 has an outer diameter of 0.35mm, an inner diameter of 0.25mm and a length of 30 cm.
In one embodiment of the present invention, the tip of the elastic sheath 7 is smooth and arc-shaped.
The invention also provides a medical article which contains the guide wire.
In one embodiment of the invention, the medical article is a thrombectomy device, a fallopian tube deocclusion device, or a urinary catheterisation device.
[ advantageous effects ]
(1) The invention provides a guide wire, which comprises a proximal isodiametric core wire section and a distal reducing core wire section, wherein the reducing core wire section comprises a proximal cutting section and a distal tip, a plurality of pairs of recesses formed by cutting are uniformly distributed on the cutting section along the axial direction, the two recesses in the same pair are symmetrically arranged relative to the axis of the reducing core wire section, the depths of the recesses are staggered, the depths of the recesses are gradually reduced from the proximal end to the distal end, and the arrangement of the cutting section (the gradually reduced recess part provides torque transmission capacity, and the non-recess part provides stable support capacity) ensures that the guide wire has stable support capacity as a whole and excellent torque transmission capacity at the same time.
(2) The invention provides a guide wire, wherein a tip end of the guide wire is provided with a tip cutting section and sleeved with a spring, an elastic sheath is wrapped outside the spring, and the arrangement of the tip end and the elastic sheath enables the part of the guide wire, preferably contacted with the inner wall of a blood vessel, to be soft enough, so that the guide wire is not easy to damage the blood vessel.
(3) The invention provides a guide wire, wherein the surfaces of a reducing core wire section and an elastic sheath of the guide wire are provided with hydrophilic coatings, and the arrangement of the hydrophilic coatings can reduce the friction force of the guide wire on a blood vessel when the guide wire passes through the blood vessel, so that the guide wire is not easy to damage the blood vessel.
(4) The invention provides a guide wire, wherein an elastic sheath of the guide wire is made of a tungsten-containing thermoplastic polymer material, and the tungsten-containing thermoplastic polymer material can increase the visibility of the guide wire in the early operation, so that the guide wire is better in operability.
Drawings
Fig. 1 is a schematic overall structure diagram of one embodiment of the guidewire of the present invention.
Fig. 2 is a schematic cross-sectional view of one embodiment of a guidewire of the present invention.
Fig. 3 is a schematic partial structural view of one embodiment of a guidewire of the present invention.
Fig. 4 is a partial structural schematic view of one embodiment of a constant diameter core wire segment of a guidewire of the present invention.
Fig. 5 is an enlarged schematic view of a portion a in fig. 4.
In fig. 1-5, a constant diameter core wire section 1, a diameter-variable core wire section 2, a cutting section 3, a tip 4, a recess 5, a spring 6, an elastic sheath 7, a straight section 8 and a sharpening section 9.
Detailed Description
The invention will be further elucidated with reference to the embodiments and the drawings.
Example 1: guide wire
Referring to fig. 1-5, the guidewire of the present invention is a guidewire comprising a proximal isodiametric guidewire segment 1 and a distal reducing guidewire segment 2; the reducing core wire section 1 comprises a cutting section 3 at the near end and a tip 4 at the far end; a plurality of pairs of cut depressions 5 are uniformly distributed on the cutting section 3 along the axial direction, two depressions 5 in the same pair are symmetrically arranged about the axis of the reducing core wire section 2, and two adjacent pairs of depressions 5 are arranged in a staggered manner.
Preferably, the tip 4 is sleeved with a spring 6; an elastic sheath 7 is wrapped outside the spring 6.
Preferably, the depth of the recess 5 tapers from the proximal end to the distal end. The cutting section is uniformly distributed with a plurality of pairs of recesses formed by cutting along the axial direction, two recesses of the same pair are symmetrically arranged about the axis of the reducing core wire section, two adjacent pairs of recesses are arranged in a staggered manner, the depth of the recesses is gradually reduced from the near end to the far end, and the arrangement of the cutting section (the gradually reduced recess part provides torque transmission capacity, and the non-recess part provides stable support capacity) ensures that the guide wire of the invention has stable support capacity as a whole and also has better torque transmission capacity.
Preferably, two adjacent pairs of recesses 5 are staggered by 180 °, or two adjacent pairs of recesses 5 are staggered by 120 °. The 180-degree staggered depressions can further improve the supporting force and the torque transmission capacity of the guide wire, and the 180-degree staggered depressions can improve the stability of the supporting force of the guide wire.
Preferably, the cutting section 3 is respectively provided with a non-cutting part and a cutting part distributed with the concave 5 from the near end to the far end; the cutting parts are respectively an A section, a B section, a C section and a D section from the near end to the far end, and the cutting conicity of the concave 5 on the A section, the B section, the C section and the D section is respectively 0.02 degrees, 0.01 degrees, 0.02 degrees and 0.01 degrees. The support force and the torque transmission capacity of the guide wire can be further improved by the cutting taper of the cutting part, and the stability of the support force of the guide wire can be improved by the cutting taper of the cutting part.
Preferably, the lengths of the sections A, B, C and D are 10cm, 10cm and 10cm, respectively.
Preferably, the length of the non-cutting portion is 10 cm.
Preferably, the cross-section of the recess 5 is annular. The arrangement of the annular recess can further improve the supporting force and the torque transmission capacity of the guide wire, and the arrangement of the annular recess can improve the stability of the supporting force of the guide wire.
Preferably, the tip 4 is composed of a straight section 8 and a cut-off sharpened section 9 from the distal end to the proximal end, and the diameter of the sharpened section 9 is gradually reduced from the proximal end to the distal end. The tip of the guide wire is provided with a tip cutting section and sleeved with a spring, the outer side of the spring is wrapped with an elastic sheath, and the arrangement of the tip and the arrangement of the elastic sheath enable the part of the guide wire, preferably contacted with the inner wall of the blood vessel, to be soft enough.
Preferably, the grinding taper of the tapered section 9 is 0.03 °.
Preferably, the straight section 8 has an outer diameter of 0.03mm and a length of 10 cm.
Preferably, the maximum outer diameter of the tapered section 8 is 0.05mm, the minimum diameter is 0.03mm, and the length is 20 cm.
Preferably, the surface of the isodiametric core silk section 1 is provided with a hydrophobic coating.
Preferably, the thickness of the hydrophobic coating on the surface of the isodiametric core wire section 1 is 0.004-0.010 mm.
Preferably, the hydrophobic coating on the surface of the isodiametric core wire section 1 is a green PTFE hydrophobic coating.
Preferably, the material of the isodiametric core wire section 1 is SS304 stainless steel.
Preferably, the equal-diameter core wire section 1 has an outer diameter of 0.35mm and a length of 100 cm.
Preferably, the surface of the reducing core wire section 2 is provided with a hydrophilic coating.
Preferably, the hydrophilic coating on the surface of the reducing core wire section 2 is a PVP polyvinylpyrrolidone hydrophilic coating.
Preferably, the thickness of the hydrophilic coating on the surface of the reducing core wire section 2 is 0.004-0.010 mm.
Preferably, the material of the reducing core wire section 2 is nickel titanium alloy.
Preferably, the diameter-variable core wire section 2 has an outer diameter of 0.35mm and a length of 95 cm.
Preferably, the equal-diameter core wire section 1 and the reducing core wire section 2 are connected through welding, and the connection firmness of the equal-diameter core wire section 1 and the reducing core wire section 2 is not lower than 10N.
Preferably, the tip 4 is made of nitinol.
Preferably, the material of the spring 6 is platinum-nickel alloy visible under radiation.
Preferably, the platinum-nickel alloy is a platinum-nickel alloy with a Pt content of 90% and a Ni content of 10%.
Preferably, the spring 6 is welded or light-fastened to the tip.
Preferably, the spring 6 has an outer diameter of 0.24mm, an inner diameter of 0.18mm, and a length of 30 cm.
Preferably, the surface of the elastic sheath 7 is provided with a hydrophilic coating.
Preferably, the hydrophilic coating on the surface of the elastic sheath 7 is a PVP-polyvinylpyrrolidone hydrophilic coating. The diameter-variable core wire section and the surface of the elastic sheath of the guide wire are provided with hydrophilic coatings, and the arrangement of the hydrophilic coatings can reduce the friction force of the guide wire on blood vessels when the guide wire passes through the blood vessels.
Preferably, the thickness of the hydrophilic coating on the surface of the elastic sheath 7 is 0.004-0.010 mm.
Preferably, the material of the elastic sheath 7 is a tungsten-containing thermoplastic polymer material.
Preferably, the content of tungsten in the tungsten-containing thermoplastic polymer material is 40 ± 2%. The elastic sheath of the guide wire is made of a tungsten-containing thermoplastic polymer material, and the visibility of the guide wire in the early operation can be improved by the tungsten-containing thermoplastic polymer material.
Preferably, the thermoplastic polymer material is one or more of polyurethane, polyethylene or rubber.
Preferably, the elastic sheath 7 has an outer diameter of 0.35mm, an inner diameter of 0.25mm and a length of 30 cm.
Preferably, the tip end of the elastic sheath 7 is formed in a smooth arc shape.
The sizes of all parts of the guide wire can be adjusted according to practical application scenes.
The torque of the guide wire can reach 1: 1.
Example 2: thrombus taking device
The thrombectomy device of the present invention comprises the guidewire of example 1.
Example 3: oviduct dredging device
The tubal deocclusion device of the present invention contains the guidewire of example 1.
Example 4: urethral catheterization device
The urinary catheterization apparatus of the present invention includes the guidewire of example 1.
Although the present invention has been described with reference to the preferred embodiments, it should be understood that various changes and modifications can be made therein by those skilled in the art without departing from the spirit and scope of the invention as defined in the appended claims.

Claims (10)

1. A guidewire comprising a proximal isodiametric guidewire segment and a distal reducing guidewire segment; the reducing core wire section comprises a cutting section at the near end and a tip at the far end; a plurality of pairs of pits formed by cutting are uniformly distributed on the cutting section along the axial direction, two pits in the same pair are symmetrically arranged about the axis of the reducing core wire section, and two adjacent pairs of pits are arranged in a staggered manner.
2. The guidewire of claim 1, wherein the tip is spring loaded; the outer side of the spring is wrapped with an elastic sheath.
3. The guidewire of claim 1, wherein the depression tapers in depth from the proximal end to the distal end.
4. A guide wire as in any of claims 1 to 3 wherein adjacent pairs of recesses are staggered by 180 °.
5. The guide wire of claim 1, wherein the cutting segment comprises a non-cutting portion and a cutting portion with distributed recesses from the proximal end to the distal end; the cutting part is respectively provided with a section A, a section B, a section C and a section D from the near end to the far end, and the cutting conicity of the depressions on the section A, the section B, the section C and the section D is respectively 0.02 degrees, 0.01 degrees, 0.02 degrees and 0.01 degrees.
6. The guidewire of claim 1, wherein the depression is annular in cross-section.
7. The guide wire of claim 1, wherein the tip is a straight section and a cut and sharpened section from the distal end to the proximal end, respectively, the sharpened section having a diameter that gradually decreases from the proximal end to the distal end.
8. The guidewire of claim 7, wherein the grinding taper of the tapered section is 0.03 °.
9. The guidewire of claim 1, wherein the isodiametric core wire segment has a hydrophobic coating on a surface thereof; the surface of the variable diameter core wire section is provided with a hydrophilic coating.
10. A medical article comprising the guidewire of any one of claims 1-9.
CN202011438372.4A 2020-12-07 2020-12-07 Medical guide wire Active CN112587782B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202011438372.4A CN112587782B (en) 2020-12-07 2020-12-07 Medical guide wire

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202011438372.4A CN112587782B (en) 2020-12-07 2020-12-07 Medical guide wire

Publications (2)

Publication Number Publication Date
CN112587782A true CN112587782A (en) 2021-04-02
CN112587782B CN112587782B (en) 2023-05-30

Family

ID=75191590

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202011438372.4A Active CN112587782B (en) 2020-12-07 2020-12-07 Medical guide wire

Country Status (1)

Country Link
CN (1) CN112587782B (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113082466A (en) * 2021-04-08 2021-07-09 哈尔滨医科大学 Guide wire
CN113181512A (en) * 2021-04-28 2021-07-30 深圳市顺美医疗股份有限公司 Advanced high-torsion-control conductive guide wire and preparation method thereof
CN113877041A (en) * 2021-10-15 2022-01-04 佛山市其右医疗科技有限公司 High-shape-retention neurovascular intervention guide wire
CN115054320A (en) * 2021-12-08 2022-09-16 上海心玮医疗科技股份有限公司 Conveying system of intracranial thrombus removal support
CN115252246A (en) * 2022-09-28 2022-11-01 微创神通医疗科技（上海）有限公司 Intracranial vascular interventional device and preparation method thereof
CN116617545A (en) * 2023-06-09 2023-08-22 株洲茂物医疗科技有限公司 Method for manufacturing guide wire and guide wire

Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0778039A1 (en) * 1995-12-07 1997-06-11 Sarcos, Inc. Catheter guide wire
JP2000509641A (en) * 1997-03-06 2000-08-02 シメッド ライフ システムズ インコーポレイテッド Guidewire with a hydrophilically coated tip
US6132389A (en) * 1998-04-23 2000-10-17 Advanced Cardiovascular Systems, Inc. Proximally tapered guidewire tip coil
US20110160680A1 (en) * 2009-12-29 2011-06-30 Cook Incorporated Wire guide with cannula
CN104623790A (en) * 2013-11-11 2015-05-20 微创神通医疗科技（上海）有限公司 Medical guide wire and conveying system
WO2016047499A1 (en) * 2014-09-26 2016-03-31 テルモ株式会社 Guide wire
US20160199620A1 (en) * 2015-01-09 2016-07-14 Mivi Neuroscience Inc. Medical guidewires for tortuous vessels
CN107361727A (en) * 2017-07-17 2017-11-21 天津大学 A kind of controllable apparatus of rigidity and its application process for natural cavity operation
US20180021546A1 (en) * 2016-07-21 2018-01-25 Creganna Unlimited Company High load steerable shaft and method for cardiac catheter
CN109125889A (en) * 2018-08-24 2019-01-04 苏州瑞帆医疗科技有限公司 A kind of seal wire that flexibility can be set and its manufacturing method
CN110354367A (en) * 2019-07-26 2019-10-22 王玉峰 Seal wire
CN110354366A (en) * 2019-06-25 2019-10-22 同济大学 A kind of power sense seal wire for CTO interventional therapy
US20200094027A1 (en) * 2017-05-26 2020-03-26 Scientia Vascular, Llc Core-wire joint with micro-fabricated medical devices
CN111840755A (en) * 2020-07-10 2020-10-30 广东海思卡尔医疗科技有限公司 Guide wire for interventional therapy

Patent Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0778039A1 (en) * 1995-12-07 1997-06-11 Sarcos, Inc. Catheter guide wire
JP2000509641A (en) * 1997-03-06 2000-08-02 シメッド ライフ システムズ インコーポレイテッド Guidewire with a hydrophilically coated tip
US6132389A (en) * 1998-04-23 2000-10-17 Advanced Cardiovascular Systems, Inc. Proximally tapered guidewire tip coil
US20110160680A1 (en) * 2009-12-29 2011-06-30 Cook Incorporated Wire guide with cannula
CN104623790A (en) * 2013-11-11 2015-05-20 微创神通医疗科技（上海）有限公司 Medical guide wire and conveying system
WO2016047499A1 (en) * 2014-09-26 2016-03-31 テルモ株式会社 Guide wire
US20160199620A1 (en) * 2015-01-09 2016-07-14 Mivi Neuroscience Inc. Medical guidewires for tortuous vessels
US20180021546A1 (en) * 2016-07-21 2018-01-25 Creganna Unlimited Company High load steerable shaft and method for cardiac catheter
US20200094027A1 (en) * 2017-05-26 2020-03-26 Scientia Vascular, Llc Core-wire joint with micro-fabricated medical devices
CN107361727A (en) * 2017-07-17 2017-11-21 天津大学 A kind of controllable apparatus of rigidity and its application process for natural cavity operation
CN109125889A (en) * 2018-08-24 2019-01-04 苏州瑞帆医疗科技有限公司 A kind of seal wire that flexibility can be set and its manufacturing method
CN110354366A (en) * 2019-06-25 2019-10-22 同济大学 A kind of power sense seal wire for CTO interventional therapy
CN110354367A (en) * 2019-07-26 2019-10-22 王玉峰 Seal wire
CN111840755A (en) * 2020-07-10 2020-10-30 广东海思卡尔医疗科技有限公司 Guide wire for interventional therapy

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113082466A (en) * 2021-04-08 2021-07-09 哈尔滨医科大学 Guide wire
CN113181512A (en) * 2021-04-28 2021-07-30 深圳市顺美医疗股份有限公司 Advanced high-torsion-control conductive guide wire and preparation method thereof
CN113877041A (en) * 2021-10-15 2022-01-04 佛山市其右医疗科技有限公司 High-shape-retention neurovascular intervention guide wire
CN115054320A (en) * 2021-12-08 2022-09-16 上海心玮医疗科技股份有限公司 Conveying system of intracranial thrombus removal support
CN115252246A (en) * 2022-09-28 2022-11-01 微创神通医疗科技（上海）有限公司 Intracranial vascular interventional device and preparation method thereof
CN115252246B (en) * 2022-09-28 2022-12-16 微创神通医疗科技（上海）有限公司 Intracranial vascular interventional device and preparation method thereof
CN116617545A (en) * 2023-06-09 2023-08-22 株洲茂物医疗科技有限公司 Method for manufacturing guide wire and guide wire
CN116617545B (en) * 2023-06-09 2024-03-22 株洲茂物医疗科技有限公司 Method for manufacturing guide wire and guide wire

Also Published As

Publication number Publication date
CN112587782B (en) 2023-05-30

Similar Documents

Publication Publication Date Title
CN112587782A (en) Medical guide wire
US20210205577A1 (en) Flexible tip catheter
JP3649604B2 (en) Guide wire to guide the catheter
US6106485A (en) Guidewire with shaped intermediate portion
JP5317566B2 (en) Catheter assembly
CA2247424C (en) Intravascular guidewire
JP5381703B2 (en) Thrombus aspiration catheter
US7390323B2 (en) Catheter
JP2008229160A (en) Catheter
CN111359077B (en) Sheath core with quick guide function used in blood vessel interventional operation
CN212067416U (en) Novel micro-guide wire structure and intracranial micro-guide wire applied to acute cerebrovascular disease
JP2009523481A (en) Titanium / molybdenum alloy guide wire
US20100168619A1 (en) Combination wire guide and method of use thereof
EP2481441A1 (en) Guidewire
US8777873B2 (en) Wire guide having a rib for coil attachment
JP2024500098A (en) Medical catheter and its manufacturing method
JP2012070979A (en) Guide wire
WO2024098930A1 (en) Microcatheter
US20230173226A1 (en) Catheter and method for engaging catheter
US6638267B1 (en) Guidewire with hypotube and internal insert
JP2018050723A (en) Support catheter and method for using the same
CN220193780U (en) Non-vascular lumen guide wire
JP5822140B2 (en) Thrombus aspiration catheter
WO2018163564A1 (en) Catheter
JP2012176190A (en) Guidewire

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant