CN112587428A - Antibacterial skin-moistening hand sanitizer and preparation method thereof - Google Patents

Antibacterial skin-moistening hand sanitizer and preparation method thereof Download PDF

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Publication number
CN112587428A
CN112587428A CN202011532659.3A CN202011532659A CN112587428A CN 112587428 A CN112587428 A CN 112587428A CN 202011532659 A CN202011532659 A CN 202011532659A CN 112587428 A CN112587428 A CN 112587428A
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fatty acid
purified water
hand sanitizer
essential oil
methyl ester
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高旭
陈小云
何学明
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Jiangsu Jinri Health Products Co ltd
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Jiangsu Jinri Health Products Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41Amines
    • A61K8/416Quaternary ammonium compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/46Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
    • A61K8/466Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfonic acid derivatives; Salts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86Polyethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The invention discloses an antibacterial skin-moistening hand sanitizer and a preparation method thereof, wherein the hand sanitizer comprises the following components: the cedar essential oil and the purified water are prepared from 1.5% of dodecyl dimethyl amine oxide, lauryl alcohol oleate, sodium fatty acid methyl ester sulfonate, sodium fatty acid polyoxyethylene ether sulfate, cedar essential oil and purified water, wherein the selection ratio of the dodecyl dimethyl amine oxide, the lauryl alcohol oleate, the sodium fatty acid methyl ester sulfonate, the sodium fatty acid polyoxyethylene ether sulfate, the cedar essential oil and the purified water is: 2.5%: 5%: 2.5%: 3.5%: 85%, the prepared hand sanitizer has good degreasing and sterilizing effects, has a good inhibiting effect on bacteria, does not hurt hands in the using process, can lubricate and maintain the skin of the hand after use, and further meets the use requirements of people on the hand sanitizer.

Description

Antibacterial skin-moistening hand sanitizer and preparation method thereof
Technical Field
The invention relates to the technical field of hand sanitizer preparation, and particularly relates to an antibacterial skin-moistening hand sanitizer and a preparation method thereof.
Background
The hand sanitizer is a skin care cleansing liquid mainly used for cleaning hands, and certain specific components can play a role in disinfection and sterilization and can be divided into a common hand sanitizer, a disinfection hand sanitizer and a heavy oil-contaminated hand sanitizer; chemical substances in the hand sanitizer can stimulate the skin of hands and are not suitable for people who are easy to be allergic to the skin, and the hand sanitizer is recommended to be applied after being washed, and is generally harmless, in the using method of the prior art, clean water is firstly used for fully wetting the hands, a proper amount of the hand sanitizer is taken to be fully kneaded by the hands in the palm for at least more than 30 seconds, the fingers and the gaps between the fingers are required to be kneaded in the process, foam can cover all parts of the whole hands, and the hand sanitizer is washed clean by running water after being kneaded; finally, care should be taken to dry with a clean dry towel or towel, preferably without drying, because the rapid evaporation of surface water can cause the skin to partially dehydrate, causing the skin to dry and become rough.
The hand sanitizer in the prior art is easy to have the following problems in use:
(1) when the hands are stained with oil stains, on one hand, the existing hand sanitizer has poor cleaning effect, and the hands are cleaned by using more hand sanitizer under normal conditions, but the cleaning effect is still not ideal, and on the other hand, in the process, more hand sanitizer is adhered to the hand surface and is difficult to clean, remains in gaps between fingertips and fingers, and can damage the hands;
(2) the hand cleaning agent only has a simple dirt removing effect on hands, bacteria adhered to the hand surface are difficult to remove, and the cleaned hands are dry, so that the hand cleaning agent is easy to cause discomfort of people and does not have a good skin care effect after cleaning.
Therefore, the invention provides an antibacterial skin-moistening hand sanitizer and a preparation method thereof, which are used for solving the problems.
Disclosure of Invention
The invention aims to provide an antibacterial skin-moistening hand sanitizer and a preparation method thereof, and aims to solve the problems in the background art.
In order to achieve the purpose, the invention provides the following technical scheme: an antibacterial skin-moistening hand sanitizer comprises the following components: dodecyl dimethyl amine oxide, lauryl alcohol oleate, sodium fatty acid methyl ester sulfonate, sodium fatty acid polyoxyethylene ether sulfate, cedar essential oil and purified water.
Preferably, the selection ratio of the dodecyl dimethyl amine oxide, the lauryl alcohol oleate, the sodium fatty acid methyl ester sulfonate, the sodium fatty acid polyoxyethylene ether sulfate, the cedar essential oil and the purified water is 1.5%: 1.5%: 6%: 4.5%: 1.5%: 85 percent.
Preferably, the selection ratio of the dodecyl dimethyl amine oxide, the lauryl alcohol oleate, the sodium fatty acid methyl ester sulfonate, the sodium fatty acid polyoxyethylene ether sulfate, the cedar essential oil and the purified water is 1.5%: 1.5%: 5%: 4.5%: 2.5%: 85 percent.
Preferably, the selection ratio of the dodecyl dimethyl amine oxide, the lauryl alcohol oleate, the sodium fatty acid methyl ester sulfonate, the sodium fatty acid polyoxyethylene ether sulfate, the cedar essential oil and the purified water is 1.5%: 2.5%: 5%: 2.5%: 3.5%: 85 percent.
Preferably, the selection proportion of the dodecyl dimethyl amine oxide, the lauryl alcohol oleate, the sodium fatty acid methyl ester sulfonate, the sodium fatty acid polyoxyethylene ether sulfate, the cedar essential oil and the purified water is 2.5%: 1.5%: 4%: 2.5%: 4.5%: 85 percent.
Preferably, the amount of the purified water in the solution is fixed, and other components are changed.
A hand sanitizer with antibacterial and skin moisturizing effects and a preparation method thereof comprise the following steps
S1: (preparation work) the above prepared raw materials are proportioned quantitatively and proportioned according to the above four proportioning methods, and placed in a specific container, and an equivalent container is prepared, wherein a hand sanitizer in the prior art is placed, and five rubber handles A, B, C, D, E adhered with greasy bacteria are prepared; (rubber handle as a hand, where E as a comparison glove for the experiment)
S2: (prefabricating) after quantitative proportioning of various medicaments, placing the medicaments in respective independent containers, then preparing four large mixed reaction container bottles, cleaning and drying the mixed reaction container bottles to prevent influence of redundant moisture and impurities on preparation (the process can avoid influence of physical factors outside an experiment on the preparation and ensure success rate of experimental preparation);
s3: firstly, adding purified water, and leaving a small amount of purified water without adding the purified water, then adding dodecyl dimethyl amine oxide, lauryl alcohol oleate, sodium fatty acid methyl ester sulfonate, sodium fatty acid polyoxyethylene ether sulfate and cedar essential oil into a mixed reaction vessel bottle according to the proportion, and respectively adding the mixture according to four proportion modes;
s4: pouring the residual purified water into a storage bottle (cleaning the storage bottle), and then pouring the residual purified water into the storage bottle, wherein the storage bottle is filled with dodecyl dimethyl amine oxide, lauryl alcohol oleate, sodium fatty acid methyl ester sulfonate, sodium fatty acid polyoxyethylene ether sulfate and cedar essential oil, shaking the storage bottle, and then pouring the obtained product into a mixed reaction container bottle (so that the phenomenon that the dodecyl dimethyl amine oxide, the lauryl alcohol oleate, the sodium fatty acid methyl ester sulfonate, the sodium fatty acid polyoxyethylene ether sulfate and the cedar essential oil are adhered to the storage bottle can be avoided, the accuracy of the proportioning of various raw materials is ensured, and further, the preparation error is avoided from being caused, and the quality of the finally prepared solution is not influenced);
s5: (inspection work) the prepared solutions were placed in four containers, and the four solutions were applied in sequence to rubber grips A, B, C, D with attached greasy bacteria, respectively, and a comparative hand sanitizer was applied to rubber grips E, and rubber grips A, B, C, D, E were rubbed at room temperature for 30 to 60 seconds, and then cleaned with clean water, and then the amount of greasy dirt on rubber grips A, B, C, D, E and the amount of bacteria on the surface thereof were observed, and finally rubber grips A, B, C, D, E were left for 10 minutes to feel the degree of dryness of the surface thereof.
Compared with the prior art, the invention has the beneficial effects that:
the preparation method of the hand sanitizer has the advantages of reasonable matching of all steps, simple process and convenience in popularization and application, the prepared hand sanitizer has good oil stain removing and bacterium removing effects, has a good inhibition effect on bacteria, does not hurt hands in the using process, and can lubricate and maintain the skin of the hands after being used, so that the using requirements of people on the hand sanitizer are met.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
EXAMPLE one (Room temperature)
The invention provides a technical scheme that: in order to achieve the purpose, the invention provides the following technical scheme: an antibacterial skin-moistening hand sanitizer comprises the following components: dodecyl dimethyl amine oxide, lauryl alcohol oleate, sodium fatty acid methyl ester sulfonate, sodium fatty acid polyoxyethylene ether sulfate, cedar essential oil and purified water.
Preferably, the selection ratio of the dodecyl dimethyl amine oxide, the lauryl alcohol oleate, the sodium fatty acid methyl ester sulfonate, the sodium fatty acid polyoxyethylene ether sulfate, the cedar essential oil and the purified water is 1.5%: 1.5%: 6%: 4.5%: 1.5%: 85 percent.
Preferably, the amount of the purified water in the solution is fixed, and other components are changed.
An antibacterial skin-moistening hand sanitizer and a preparation method thereof, comprising the following steps:
s1: (preparation work) the above prepared raw materials are proportioned quantitatively and proportioned according to the above four proportioning methods, and placed in a specific container, and an equivalent container is prepared, wherein a hand sanitizer in the prior art is placed, and five rubber handles A, B, C, D, E adhered with greasy bacteria are prepared; (rubber handle as a hand, where E as a comparison glove for the experiment)
S2: (prefabricating) after quantitative proportioning of various medicaments, placing the medicaments in respective independent containers, then preparing four large mixed reaction container bottles, cleaning and drying the mixed reaction container bottles to prevent influence of redundant moisture and impurities on preparation (the process can avoid influence of physical factors outside an experiment on the preparation and ensure success rate of experimental preparation);
s3: firstly, adding purified water, and leaving a small amount of purified water without adding the purified water, then adding dodecyl dimethyl amine oxide, lauryl alcohol oleate, sodium fatty acid methyl ester sulfonate, sodium fatty acid polyoxyethylene ether sulfate and cedar essential oil into a mixed reaction vessel bottle according to the proportion, and respectively adding the mixture according to four proportion modes;
s4: pouring the residual purified water into a storage bottle (cleaning the storage bottle), and then pouring the residual purified water into the storage bottle, wherein the storage bottle is filled with dodecyl dimethyl amine oxide, lauryl alcohol oleate, sodium fatty acid methyl ester sulfonate, sodium fatty acid polyoxyethylene ether sulfate and cedar essential oil, shaking the storage bottle, and then pouring the obtained product into a mixed reaction container bottle (so that the phenomenon that the dodecyl dimethyl amine oxide, the lauryl alcohol oleate, the sodium fatty acid methyl ester sulfonate, the sodium fatty acid polyoxyethylene ether sulfate and the cedar essential oil are adhered to the storage bottle can be avoided, the accuracy of the proportioning of various raw materials is ensured, and further, the preparation error is avoided from being caused, and the quality of the finally prepared solution is not influenced);
s5: (inspection work) the prepared solutions were placed in four containers, and the four solutions were applied in sequence to rubber grips A, B, C, D with attached greasy bacteria, respectively, and a comparative hand sanitizer was applied to rubber grips E, and rubber grips A, B, C, D, E were rubbed at room temperature for 30 to 60 seconds, and then cleaned with clean water, and then the amount of greasy dirt on rubber grips A, B, C, D, E and the amount of bacteria on the surface thereof were observed, and finally rubber grips A, B, C, D, E were left for 10 minutes to feel the degree of dryness of the surface thereof.
Example two (Room temperature)
The invention provides a technical scheme that: in order to achieve the purpose, the invention provides the following technical scheme: an antibacterial skin-moistening hand sanitizer comprises the following components: dodecyl dimethyl amine oxide, lauryl alcohol oleate, sodium fatty acid methyl ester sulfonate, sodium fatty acid polyoxyethylene ether sulfate, cedar essential oil and purified water.
Preferably, the selection ratio of the dodecyl dimethyl amine oxide, the lauryl alcohol oleate, the sodium fatty acid methyl ester sulfonate, the sodium fatty acid polyoxyethylene ether sulfate, the cedar essential oil and the purified water is 1.5%: 1.5%: 5%: 4.5%: 2.5%: 85 percent.
Preferably, the amount of the purified water in the solution is fixed, and other components are changed.
An antibacterial skin-moistening hand sanitizer and a preparation method thereof, comprising the following steps:
s1: (preparation work) the above prepared raw materials are proportioned quantitatively and proportioned according to the above four proportioning methods, and placed in a specific container, and an equivalent container is prepared, wherein a hand sanitizer in the prior art is placed, and five rubber handles A, B, C, D, E adhered with greasy bacteria are prepared; (rubber handle as a hand, where E as a comparison glove for the experiment)
S2: (prefabricating) after quantitative proportioning of various medicaments, placing the medicaments in respective independent containers, then preparing four large mixed reaction container bottles, cleaning and drying the mixed reaction container bottles to prevent influence of redundant moisture and impurities on preparation (the process can avoid influence of physical factors outside an experiment on the preparation and ensure success rate of experimental preparation);
s3: firstly, adding purified water, and leaving a small amount of purified water without adding the purified water, then adding dodecyl dimethyl amine oxide, lauryl alcohol oleate, sodium fatty acid methyl ester sulfonate, sodium fatty acid polyoxyethylene ether sulfate and cedar essential oil into a mixed reaction vessel bottle according to the proportion, and respectively adding the mixture according to four proportion modes;
s4: pouring the residual purified water into a storage bottle (cleaning the storage bottle), and then pouring the residual purified water into the storage bottle, wherein the storage bottle is filled with dodecyl dimethyl amine oxide, lauryl alcohol oleate, sodium fatty acid methyl ester sulfonate, sodium fatty acid polyoxyethylene ether sulfate and cedar essential oil, shaking the storage bottle, and then pouring the obtained product into a mixed reaction container bottle (so that the phenomenon that the dodecyl dimethyl amine oxide, the lauryl alcohol oleate, the sodium fatty acid methyl ester sulfonate, the sodium fatty acid polyoxyethylene ether sulfate and the cedar essential oil are adhered to the storage bottle can be avoided, the accuracy of the proportioning of various raw materials is ensured, and further, the preparation error is avoided from being caused, and the quality of the finally prepared solution is not influenced);
s5: (inspection work) the prepared solutions were placed in four containers, and the four solutions were applied in sequence to rubber grips A, B, C, D with attached greasy bacteria, respectively, and a comparative hand sanitizer was applied to rubber grips E, and rubber grips A, B, C, D, E were rubbed at room temperature for 30 to 60 seconds, and then cleaned with clean water, and then the amount of greasy dirt on rubber grips A, B, C, D, E and the amount of bacteria on the surface thereof were observed, and finally rubber grips A, B, C, D, E were left for 10 minutes to feel the degree of dryness of the surface thereof.
EXAMPLE III (Room temperature)
The invention provides a technical scheme that: in order to achieve the purpose, the invention provides the following technical scheme: an antibacterial skin-moistening hand sanitizer comprises the following components: dodecyl dimethyl amine oxide, lauryl alcohol oleate, sodium fatty acid methyl ester sulfonate, sodium fatty acid polyoxyethylene ether sulfate, cedar essential oil and purified water.
Preferably, the selection ratio of the dodecyl dimethyl amine oxide, the lauryl alcohol oleate, the sodium fatty acid methyl ester sulfonate, the sodium fatty acid polyoxyethylene ether sulfate, the cedar essential oil and the purified water is 1.5%: 2.5%: 5%: 2.5%: 3.5%: 85 percent.
Preferably, the amount of the purified water in the solution is fixed, and other components are changed.
An antibacterial skin-moistening hand sanitizer and a preparation method thereof, comprising the following steps:
s1: (preparation work) the above prepared raw materials are proportioned quantitatively and proportioned according to the above four proportioning methods, and placed in a specific container, and an equivalent container is prepared, wherein a hand sanitizer in the prior art is placed, and five rubber handles A, B, C, D, E adhered with greasy bacteria are prepared; (rubber handle as a hand, where E as a comparison glove for the experiment)
S2: (prefabricating) after quantitative proportioning of various medicaments, placing the medicaments in respective independent containers, then preparing four large mixed reaction container bottles, cleaning and drying the mixed reaction container bottles to prevent influence of redundant moisture and impurities on preparation (the process can avoid influence of physical factors outside an experiment on the preparation and ensure success rate of experimental preparation);
s3: firstly, adding purified water, and leaving a small amount of purified water without adding the purified water, then adding dodecyl dimethyl amine oxide, lauryl alcohol oleate, sodium fatty acid methyl ester sulfonate, sodium fatty acid polyoxyethylene ether sulfate and cedar essential oil into a mixed reaction vessel bottle according to the proportion, and respectively adding the mixture according to four proportion modes;
s4: pouring the residual purified water into a storage bottle (cleaning the storage bottle), and then pouring the residual purified water into the storage bottle, wherein the storage bottle is filled with dodecyl dimethyl amine oxide, lauryl alcohol oleate, sodium fatty acid methyl ester sulfonate, sodium fatty acid polyoxyethylene ether sulfate and cedar essential oil, shaking the storage bottle, and then pouring the obtained product into a mixed reaction container bottle (so that the phenomenon that the dodecyl dimethyl amine oxide, the lauryl alcohol oleate, the sodium fatty acid methyl ester sulfonate, the sodium fatty acid polyoxyethylene ether sulfate and the cedar essential oil are adhered to the storage bottle can be avoided, the accuracy of the proportioning of various raw materials is ensured, and further, the preparation error is avoided from being caused, and the quality of the finally prepared solution is not influenced);
s5: (inspection work) the prepared solutions were placed in four containers, and the four solutions were applied in sequence to rubber grips A, B, C, D with attached greasy bacteria, respectively, and a comparative hand sanitizer was applied to rubber grips E, and rubber grips A, B, C, D, E were rubbed at room temperature for 30 to 60 seconds, and then cleaned with clean water, and then the amount of greasy dirt on rubber grips A, B, C, D, E and the amount of bacteria on the surface thereof were observed, and finally rubber grips A, B, C, D, E were left for 10 minutes to feel the degree of dryness of the surface thereof.
EXAMPLE four (Room temperature)
The invention provides a technical scheme that: in order to achieve the purpose, the invention provides the following technical scheme: an antibacterial skin-moistening hand sanitizer comprises the following components: dodecyl dimethyl amine oxide, lauryl alcohol oleate, sodium fatty acid methyl ester sulfonate, sodium fatty acid polyoxyethylene ether sulfate, cedar essential oil and purified water.
Preferably, the selection proportion of the dodecyl dimethyl amine oxide, the lauryl alcohol oleate, the sodium fatty acid methyl ester sulfonate, the sodium fatty acid polyoxyethylene ether sulfate, the cedar essential oil and the purified water is 2.5%: 1.5%: 4%: 2.5%: 4.5%: 85 percent.
Preferably, the amount of the purified water in the solution is fixed, and other components are changed.
An antibacterial skin-moistening hand sanitizer and a preparation method thereof, comprising the following steps:
s1: (preparation work) the above prepared raw materials are proportioned quantitatively and proportioned according to the above four proportioning methods, and placed in a specific container, and an equivalent container is prepared, wherein a hand sanitizer in the prior art is placed, and five rubber handles A, B, C, D, E adhered with greasy bacteria are prepared; (rubber handle as a hand, where E as a comparison glove for the experiment)
S2: (prefabricating) after quantitative proportioning of various medicaments, placing the medicaments in respective independent containers, then preparing four large mixed reaction container bottles, cleaning and drying the mixed reaction container bottles to prevent influence of redundant moisture and impurities on preparation (the process can avoid influence of physical factors outside an experiment on the preparation and ensure success rate of experimental preparation);
s3: firstly, adding purified water, and leaving a small amount of purified water without adding the purified water, then adding dodecyl dimethyl amine oxide, lauryl alcohol oleate, sodium fatty acid methyl ester sulfonate, sodium fatty acid polyoxyethylene ether sulfate and cedar essential oil into a mixed reaction vessel bottle according to the proportion, and respectively adding the mixture according to four proportion modes;
s4: pouring the residual purified water into a storage bottle (cleaning the storage bottle), and then pouring the residual purified water into the storage bottle, wherein the storage bottle is filled with dodecyl dimethyl amine oxide, lauryl alcohol oleate, sodium fatty acid methyl ester sulfonate, sodium fatty acid polyoxyethylene ether sulfate and cedar essential oil, shaking the storage bottle, and then pouring the obtained product into a mixed reaction container bottle (so that the phenomenon that the dodecyl dimethyl amine oxide, the lauryl alcohol oleate, the sodium fatty acid methyl ester sulfonate, the sodium fatty acid polyoxyethylene ether sulfate and the cedar essential oil are adhered to the storage bottle can be avoided, the accuracy of the proportioning of various raw materials is ensured, and further, the preparation error is avoided from being caused, and the quality of the finally prepared solution is not influenced);
s5: (inspection work) the prepared solutions were placed in four containers, and the four solutions were applied in sequence to rubber grips A, B, C, D with attached greasy bacteria, respectively, and a comparative hand sanitizer was applied to rubber grips E, and rubber grips A, B, C, D, E were rubbed at room temperature for 30 to 60 seconds, and then cleaned with clean water, and then the amount of greasy dirt on rubber grips A, B, C, D, E and the amount of bacteria on the surface thereof were observed, and finally rubber grips A, B, C, D, E were left for 10 minutes to feel the degree of dryness of the surface thereof.
Comparative example: the rubber handle E is kneaded for 30 to 60 seconds at room temperature by using common hand sanitizer and the rubber handle E adhered with greasy dirt bacteria, then cleaned by using clean water, and finally placed for 10 minutes to feel the surface dryness of the rubber handle E.
The hand sanitizer is prepared by the four groups of embodiments, firstly, the hand sanitizer has good effect on removing oil stains, bacteria remained on the rubber gloves in the embodiments can achieve good bacteriostatic effect compared with a comparative example, the rubber gloves in the embodiments are smooth and mellow compared with the comparative example, but the result obtained by comparison among the four groups of embodiments is that the hand sanitizer prepared in the third embodiment has the best use effect, the oil stains on the rubber handle C washed by the hand sanitizer in the third embodiment are the least, the bacteria content is the least, and the surface of the rubber handle C is the most smooth and mellow, so that the requirements of people on bacteriostasis, skin moistening and quick oil stain removal are met.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (7)

1. The bacteriostatic skin-moistening hand sanitizer is characterized in that: comprises the following components: dodecyl dimethyl amine oxide, lauryl alcohol oleate, sodium fatty acid methyl ester sulfonate, sodium fatty acid polyoxyethylene ether sulfate, cedar essential oil and purified water.
2. The bacteriostatic skin-moisturizing hand sanitizer according to claim 1, which is characterized in that: the selection proportion of the dodecyl dimethyl amine oxide, the lauryl alcohol oleate, the fatty acid methyl ester sodium sulfonate, the fatty acid polyoxyethylene ether sodium sulfate, the cedar essential oil and the purified water is 1.5 percent: 1.5%: 6%: 4.5%: 1.5%: 85 percent.
3. The bacteriostatic skin-moisturizing hand sanitizer according to claim 1, which is characterized in that: the selection proportion of the dodecyl dimethyl amine oxide, the lauryl alcohol oleate, the fatty acid methyl ester sodium sulfonate, the fatty acid polyoxyethylene ether sodium sulfate, the cedar essential oil and the purified water is 1.5 percent: 1.5%: 5%: 4.5%: 2.5%: 85 percent.
4. The bacteriostatic skin-moisturizing hand sanitizer according to claim 1, which is characterized in that: the selection proportion of the dodecyl dimethyl amine oxide, the lauryl alcohol oleate, the fatty acid methyl ester sodium sulfonate, the fatty acid polyoxyethylene ether sodium sulfate, the cedar essential oil and the purified water is 1.5 percent: 2.5%: 5%: 2.5%: 3.5%: 85 percent.
5. The bacteriostatic skin-moisturizing hand sanitizer according to claim 1, which is characterized in that: the selection proportion of the dodecyl dimethyl amine oxide, the lauryl alcohol oleate, the fatty acid methyl ester sodium sulfonate, the fatty acid polyoxyethylene ether sodium sulfate, the cedar essential oil and the purified water is 2.5 percent: 1.5%: 4%: 2.5%: 4.5%: 85 percent.
6. The bacteriostatic skin-moisturizing hand sanitizer according to claim 1, which is characterized in that: the amount of the purified water in the solution is fixed, and other components are changed.
7. The bacteriostatic skin-moistening hand sanitizer according to any one of claims 1 to 6 and the preparation method thereof, characterized by comprising the following steps
S1: (preparation work) the above prepared raw materials are proportioned quantitatively and proportioned according to the above four proportioning methods, and placed in a specific container, and an equivalent container is prepared, wherein a hand sanitizer in the prior art is placed, and five rubber handles A, B, C, D, E adhered with greasy bacteria are prepared; (rubber handle as a hand, where E as a comparison glove for the experiment)
S2: (prefabricating) after quantitative proportioning of various medicaments, placing the medicaments in respective independent containers, then preparing four large mixed reaction container bottles, cleaning and drying the mixed reaction container bottles to prevent influence of redundant moisture and impurities on preparation (the process can avoid influence of physical factors outside an experiment on the preparation and ensure success rate of experimental preparation);
s3: firstly, adding purified water, and leaving a small amount of purified water without adding the purified water, then adding dodecyl dimethyl amine oxide, lauryl alcohol oleate, sodium fatty acid methyl ester sulfonate, sodium fatty acid polyoxyethylene ether sulfate and cedar essential oil into a mixed reaction vessel bottle according to the proportion, and respectively adding the mixture according to four proportion modes;
s4: pouring the residual purified water into a storage bottle (cleaning the storage bottle), and then pouring the residual purified water into the storage bottle, wherein the storage bottle is filled with dodecyl dimethyl amine oxide, lauryl alcohol oleate, sodium fatty acid methyl ester sulfonate, sodium fatty acid polyoxyethylene ether sulfate and cedar essential oil, shaking the storage bottle, and then pouring the obtained product into a mixed reaction container bottle (so that the phenomenon that the dodecyl dimethyl amine oxide, the lauryl alcohol oleate, the sodium fatty acid methyl ester sulfonate, the sodium fatty acid polyoxyethylene ether sulfate and the cedar essential oil are adhered to the storage bottle can be avoided, the accuracy of the proportioning of various raw materials is ensured, and further, the preparation error is avoided from being caused, and the quality of the finally prepared solution is not influenced);
s5: (inspection work) the prepared solutions were placed in four containers, and the four solutions were applied in sequence to rubber grips A, B, C, D with attached greasy bacteria, respectively, and a comparative hand sanitizer was applied to rubber grips E, and rubber grips A, B, C, D, E were rubbed at room temperature for 30 to 60 seconds, and then cleaned with clean water, and then the amount of greasy dirt on rubber grips A, B, C, D, E and the amount of bacteria on the surface thereof were observed, and finally rubber grips A, B, C, D, E were left for 10 minutes to feel the degree of dryness of the surface thereof.
CN202011532659.3A 2020-12-22 2020-12-22 Antibacterial skin-moistening hand sanitizer and preparation method thereof Pending CN112587428A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103565678A (en) * 2013-11-12 2014-02-12 上海方木精细化工有限公司 Mint liquid soap
CN105326680A (en) * 2015-10-31 2016-02-17 夏子煜 Hand sanitizer for children

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103565678A (en) * 2013-11-12 2014-02-12 上海方木精细化工有限公司 Mint liquid soap
CN105326680A (en) * 2015-10-31 2016-02-17 夏子煜 Hand sanitizer for children

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