CN112336787A - Ointment for treating burns and scalds and preparation method thereof - Google Patents
Ointment for treating burns and scalds and preparation method thereof Download PDFInfo
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- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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Abstract
The invention relates to an ointment for treating burns and scalds and a preparation method thereof, wherein the ointment comprises 20 parts of angelica, 11 parts of Chinese taxillus herb, 12 parts of rhubarb, 17 parts of phellodendron, 10 parts of honeysuckle, 23 parts of medical beeswax and 48 parts of sesame oil.
Description
Technical Field
The invention relates to the field of treating burns and scalds by traditional Chinese medicines, in particular to ointment for treating burns and scalds and a preparation method thereof.
Background
Burn and scald are common clinical frequently encountered diseases, and the disease degree, area and parts are different. For three-degree burns and scalds, the injury is characterized by eschar, the whole skin layer, subcutaneous tissues deeply reaching muscles, bones and muscles, no elasticity and pain of the skin, hard skin like leather, white wax, brown and yellow, dry charred skin, dry meat, rotten bones and the like. Clinically, the traditional Chinese medicine has the characteristics of long-term old burn and scald injury, persistent malignant sore due to degeneration, diffusion and infection, and the like. Therefore, serious consequences are caused to patients, the health of people is affected, inconvenience is brought to work, study, labor and life, the mental mood of the patients is anxious and uneasy, the sleep is not good enough, even the patients have lifelong disabilities, or the life safety is endangered. At present, no relevant effective traditional Chinese medicine ointment is seen for treating the burns and scalds, particularly three-degree or deep three-degree burns and scalds, and old burns and scalds which cannot be cured for a long time. Clinically, the externally applied traditional Chinese medicine ointment for treating burns and scalds has various purposes, wherein the ointment can effectively moisten the burns and scalds, has certain defects in the effects of treating the three-degree burn and scald, depth burn and scald and old burn and scald, has unsatisfactory treatment effects in the aspects of resisting infection, healing sore and promoting granulation, sterilizing, controlling seepage, healing wounds and the like, is easy to generate toxic and side effects, and has low cure rate. Based on the above, the invention provides the traditional Chinese medicine ointment for treating the burn diseases, which has the effects of clearing heat, cooling blood, detoxifying, promoting granulation and healing sore.
Disclosure of Invention
The invention aims to provide an ointment for treating burns and scalds and a preparation method thereof, and solves the problems of difficult granulation and sore healing and slow wound healing of the existing ointment for treating burns and scalds, particularly treating third-degree or deep third-degree burns and scalds and old burns and scalds which cannot be healed for a long time.
The invention also aims to provide a preparation method of the traditional Chinese medicine ointment.
The invention adopts the technical scheme that the ointment for treating burns and scalds and the preparation method thereof comprise the following substances in parts by weight: 15-25 parts of angelica, 5-15 parts of Chinese taxillus herb, 5-15 parts of rhubarb, 10-20 parts of phellodendron, 7-12 parts of honeysuckle, 20-30 parts of medical beeswax and 40-55 parts of sesame oil.
Preferably, the ointment for treating burns and scalds comprises the following substances in parts by weight: 18-22 parts of angelica, 8-12 parts of Chinese taxillus herb, 9-13 parts of rhubarb, 13-19 parts of phellodendron, 9-11 parts of honeysuckle, 22-26 parts of medical beeswax and 45-50 parts of sesame oil.
Preferably, the ointment for treating burns and scalds comprises the following substances in parts by weight: 20 parts of angelica, 11 parts of Chinese taxillus herb, 12 parts of rhubarb, 17 parts of phellodendron, 10 parts of honeysuckle, 23 parts of medical beeswax and 48 parts of sesame oil.
Preferably, the preparation method of the ointment for treating burns and scalds is characterized by comprising the following steps:
step 1, weighing 20 parts of angelica, 11 parts of herba taxilli, 12 parts of rheum officinale, 17 parts of phellodendron and 10 parts of honeysuckle according to parts by weight, preferably selecting, slicing and removing impurities, then decocting and extracting twice by using purified water, standing for 1-2 hours, and preserving in another container;
and 2, adding 8-13% of medical beeswax and 55-75% of sesame oil by mass into the substance obtained in the step 1, mixing and heating until the medical beeswax and the sesame oil are fully dissolved, continuously heating and stirring until the liquid does not overflow to form a thick liquid of the glue juice, removing the fire and annealing the gas, and removing the oil and condensing the smoke gas to obtain the ointment for treating the burn and scald.
Preferably, the preparation method of the ointment for treating burns and scalds is that the purified water boiling temperature is 100 ℃, and the time duration is 30-50 minutes.
Preferably, the heating and stirring is continuous clockwise stirring.
Preferably, the preparation method of the ointment for treating burns and scalds is characterized in that the ointment is extracted twice and filtered through a 80-100-mesh gauze double-layer filter.
The invention has the beneficial effects that: the ointment comprehensively compatible with the traditional Chinese medicine ointment has the effects of clearing heat and cooling blood, detoxifying and healing wound and promoting tissue regeneration and healing, can be used for efficiently treating burns and scalds, particularly three-degree or deep three-degree burns and scalds and old burns and scalds which cannot be healed for a long time, can quickly promote tissue regeneration and heal wound, is beneficial to wound healing, and has high cure rate; unique and mild medicinal effect, no toxic or side effect, economy and practicality.
In conclusion, through research and proportioning experiments for many years, the invention aims to provide a Chinese medicinal composition for treating burns and scalds, which is efficient, convenient, safe and free from toxic and side effects, has low cost, and can gradually recover the burns and scalds, is convenient to use and popularize, and aims to solve and improve the beneficial effect that in the field of treating burns and scalds at home and abroad, a preferable scheme except western skin grafting can save a large amount of medical resources for the country and society.
Detailed Description
The present invention is further illustrated by the following examples, which are not to be construed as limiting the invention.
The invention adopts the technical scheme that the ointment for treating burns and scalds and the preparation method thereof comprise the following substances in parts by weight: 15-25 parts of angelica, 5-15 parts of Chinese taxillus herb, 5-15 parts of rhubarb, 10-20 parts of phellodendron, 7-12 parts of honeysuckle, 20-30 parts of medical beeswax and 40-55 parts of sesame oil.
Preferably, the ointment for treating burns and scalds comprises the following substances in parts by weight: 18-22 parts of angelica, 8-12 parts of Chinese taxillus herb, 9-13 parts of rhubarb, 13-19 parts of phellodendron, 9-11 parts of honeysuckle, 22-26 parts of medical beeswax and 45-50 parts of sesame oil.
Preferably, the ointment for treating burns and scalds comprises the following substances in parts by weight: 20 parts of angelica, 11 parts of Chinese taxillus herb, 12 parts of rhubarb, 17 parts of phellodendron, 10 parts of honeysuckle, 23 parts of medical beeswax and 48 parts of sesame oil.
Preferably, the preparation method of the ointment for treating burns and scalds is characterized by comprising the following steps:
step 1, weighing 20 parts of angelica, 11 parts of herba taxilli, 12 parts of rheum officinale, 17 parts of phellodendron and 10 parts of honeysuckle according to parts by weight, preferably selecting, slicing and removing impurities, then decocting and extracting twice by using purified water, standing for 1-2 hours, and preserving in another container;
and 2, adding 8-13% of medical beeswax and 55-75% of sesame oil by mass into the substance obtained in the step 1, mixing and heating until the medical beeswax and the sesame oil are fully dissolved, continuously heating and stirring until the liquid does not overflow to form a thick liquid of the glue juice, removing the fire and annealing the gas, and removing the oil and condensing the smoke gas to obtain the ointment for treating the burn and scald.
Preferably, the preparation method of the ointment for treating burns and scalds is that the purified water boiling temperature is 100 ℃, and the time duration is 30-50 minutes.
Preferably, the heating and stirring is continuous clockwise stirring.
Preferably, the preparation method of the ointment for treating burns and scalds is characterized in that the ointment is extracted twice and filtered through a 80-100-mesh gauze double-layer filter.
The functions and the main functions of the raw materials in the traditional Chinese medicine paste are as follows:
the formula of the ointment of the invention selects 5 traditional Chinese medicines of angelica, monkshood, rhubarb, phellodendron and honeysuckle to be combined to generate a synergistic effect. The medicine has the beneficial effects of clearing heat, cooling blood, relieving pain, detoxifying, healing sore, promoting blood circulation and removing blood stasis on the treatment of serious burn, and has obvious effect on treating water and fire injury skin. Modern researches show that the traditional Chinese medicine has the effects of stopping bleeding and relieving pain on flesh decay bleeding. Has the functions of resisting bacteria and controlling diffusion of staphylococcus aureus infected by the burnt surface of the body surface skin and resisting the hyperplasia of granulation tissues. It has the actions of clearing heat, cooling blood, subduing swelling, removing toxicity, promoting granulation and healing wound, and can reduce exudation, relieve pain and promote healing. For a series of symptoms of severe burn, such as septicemia and coma, the two medicines can be effectively controlled and treated, wherein the symptoms of severe burn are caused by exuberance of fire toxin, yin injury and fluid consumption, deficiency of pathogenic toxin fluid entering nutrient, disharmony of internal organs, imbalance of yin and yang, and the like. The traditional Chinese medicine has strong general reaction to serious burn, should be used by internal and external methods, and treat the symptoms in an urgent way, and should be taken orally immediately to clear ying and detoxify and the like, so that the patient can go through coma and shock periods safely. Effectively controlling the stable state of the septicemia and creating conditions for future treatment. The external burn ointment is fully coated on the wound surface all day, detoxifies, permeates the skin, reduces swelling, sterilizes and protects the damaged skin.
The ointment for treating burns and scalds has obvious effect of controlling seepage, and the assistant principal drugs play a better role in treatment and are used as adjuvant drugs. The traditional Chinese medicine has spectrum antibacterial effect and can recover from various virus infection-caused obstacles. The injury can be detoxified, the decay is removed, the sterility and the infection are kept, and the healing is accelerated. Thereby having stronger control effect on dermatophytes. The effect of the medicament is superior to that of western antibiotics in the burn treatment process, and an environment beneficial to promoting tissue regeneration and recovering is created for the burn.
The burn and scald ointment is a main effective and common traditional Chinese medicine ointment for treating skin diseases in the department of ulcer in all generations, has good effects of detoxifying, reducing swelling, killing parasites, removing necrotic tissue, promoting granulation, healing sore, astringing, stopping bleeding and relieving pain, and achieves satisfactory effects when being used together with main and auxiliary medicines for treating third-degree burn and old and non-healing burn. In addition to the above effects, each Chinese medicinal ointment also has specific effects. In addition, the medicine has the functions of promoting blood circulation, removing blood stasis, removing putrefaction and promoting tissue regeneration, so that the necrotic tissue is quickly fallen off, and the granulation of the regenerated tissue is accelerated to heal. The medicine has good and quick healing effect on burns which can not heal slough for a long time and can not promote tissue regeneration and grow flesh, especially on individual disabled people who have dead bone and can affect tissue regeneration and grow flesh, and the burn can be prevented from falling off due to bone and flesh separation by self when fingers are cut by an operation. It is especially suitable for promoting granulation, astringing and healing. Particularly in the later recovery stage of third-degree burn, the clinical findings show that the new granulation on the bone surface after slough is shed is connected into a fresh granulation from small to large, the enclosed bone is perfect, the separation and shedding of dead bones are accelerated, the new muscle is plump and durable, and no obvious pigment texture exists on the new wound surface. The effect that can not be expected is achieved in the burn recovery stage, and limb cutting operation is avoided.
The coordination and coordination of the medicines achieve the specific effects of clearing heat, cooling blood, removing toxin, activating blood circulation, removing stasis, removing putrefaction, promoting wound healing, promoting granulation and healing, and the invention is completed.
Example 1
Step 1, weighing the following components in parts by weight: 15 parts of angelica, 5 parts of herba taxilli, 5 parts of rhubarb, 10 parts of phellodendron and 7 parts of honeysuckle are preferably selected, sliced and subjected to impurity removal, then the mixture is boiled and extracted twice by purified water, and the mixture is kept still for 1 to 2 hours and stored in another container.
And 2, adding 8-13% of medical beeswax and 55-75% of sesame oil by mass into the substance obtained in the step 1, mixing and heating until the medical beeswax and the sesame oil are fully dissolved, continuously heating and stirring until the liquid does not overflow to form a thick liquid of the glue juice, removing the fire and annealing the gas, and removing the oil and condensing the smoke gas to obtain the ointment for treating the burn and scald.
Example 2
Step 1, weighing the following components in parts by weight: 25 parts of angelica, 15 parts of herba taxilli, 15 parts of rhubarb, 20 parts of phellodendron and 12 parts of honeysuckle are preferably selected, sliced and subjected to impurity removal, then the mixture is boiled and extracted twice by purified water, and the mixture is kept still for 1 to 2 hours and stored in another container.
And 2, adding 8-13% of medical beeswax and 55-75% of sesame oil by mass into the substance obtained in the step 1, mixing and heating until the medical beeswax and the sesame oil are fully dissolved, continuously heating and stirring until the liquid does not overflow to form a thick liquid of the glue juice, removing the fire and annealing the gas, and removing the oil and condensing the smoke gas to obtain the ointment for treating the burn and scald.
Example 3
Step 1, weighing the following components in parts by weight: 20 parts of angelica, 11 parts of Chinese taxillus herb, 12 parts of rhubarb, 17 parts of phellodendron and 10 parts of honeysuckle flower are preferably selected, sliced and subjected to impurity removal, then the mixture is boiled and extracted twice by purified water, and the mixture is kept still for 1 to 2 hours and stored in another container.
And 2, adding 8-13% of medical beeswax and 55-75% of sesame oil by mass into the substance obtained in the step 1, mixing and heating until the medical beeswax and the sesame oil are fully dissolved, continuously heating and stirring until the liquid does not overflow to form a thick liquid of the glue juice, removing the fire and annealing the gas, and removing the oil and condensing the smoke gas to obtain the ointment for treating the burn and scald.
The clinical use condition and the clinical curative effect observation of the traditional Chinese medicine paste for treating the burn and scald are carried out.
First, clinical comparison of the use conditions
9 patients were treated in outpatient clinic, wherein 5 men and 4 women, and 5 patients aged 20 to 50 years old with third or deep degree burn and scald and old burn and scald which can not be cured for a long time were treated by clinical contrast observation. The 9 persons used for comparative observation were divided into 3 groups, a group a, a group B, and a group C, each group having 3 persons.
The group A is treated with SANHUANG ointment 2 times a day, and covered with gauze coated with ointment for 15 days.
Group B is treated with the wet burn ointment 2 times a day, and wrapped with gauze for 15 days.
The ointment for healing burn and scald is applied for 3 times a day, and the ointment is applied externally, covered with gauze and kept warm for 15 days.
The treatment results are as follows:
the red swelling of group A subsides, the exudation is reduced, and the skin is slightly itchy and uncomfortable.
The exudation of the B group has no red swelling, no slough and no wound healing, poor granulation promoting effect, and grey red wound skin
After the medicine is taken, the medicine is free from inflammation, has the effects of healing sore, promoting granulation, healing wound, and promoting wound healing, and the regenerated granulation is ruddy and bright, has no scar texture, and can heal the wound surface quickly. The three groups respectively count that the cure rate of the group A is 55%, the cure rate of the group B is more than 65%, the cure rate of the group C is 100%, and the comparison shows that the group C has obvious treatment effect.
Second, observation of clinical curative effect
General data overview:
9 patients are treated in outpatient clinic, wherein 6 men and 3 women have the treatment and observation effects of 9 third-degree or deep third-degree burns and scalds selected from outpatient clinic treatment cases and old burns and scalds which are not cured for a long time in the ages of 20 years and 50 years.
Clinical symptoms of diagnosis:
the skin is eschar, hurt the whole layer and reach the muscles and bones, the hard and black skin or the wax white eschar is dry, the bones are exposed and the flesh is rotten, the seepage is much, the skin is red and swollen, the deficiency of both qi and blood, the face is yellow and white, the skin is soft and weak, and the pulse is weak.
The treatment method comprises the following steps:
the dressing is changed 3 times per day as the debridement ointment, and the gauze on the outer cover is covered for 10 days for 1 treatment course, and 3 treatment courses are used continuously.
Treatment evaluation: after each burn patient is treated, the total cure rate is 100 percent, and the effect of the treatment requirement is achieved.
6 the human body has good wound surface granulation promoting and sore healing without scars, the wound surface is fast to heal, slight textures exist, the normal diet has red, moist, healthy and strong face, the mental state is good, and no adverse reaction exists after 10 days of healing.
3, the patient has serious wound, the slough skin is later damaged and shed, the tissue regeneration and the flesh growth are good, the injured skin is plump and ruddy, the scar is not obvious, the mental recovery is good, the housework can be managed, and no side effect occurs after the patient is cured in 15 days. Normal diet, strong body, powerful pulse, red, thin and greasy tongue coating.
In order to further understand the remarkable curative effect of the traditional Chinese medicine ointment for treating burns and scalds, disclosed by the invention, in treating third-degree or deep third-degree burns and scalds and old burns and scalds which cannot be cured for a long time, 3 cases are preferably selected to further explain the clinical use condition.
Clinical use case one
Yanchuan county Liujia river village children, 5 years old men. In one day and in villages, a plurality of children are in wheat fields, the pasture is lighted to play, the wind is strong, the fire is strong, the smoke is thick, the direction is lost when the children escape, the hands are burnt to be black by the fire, the red and swollen water bubbles are connected, the children live in the area to treat the disease in the same day due to severe pain, and the children return to Yanchuan after five days. The traditional Chinese medicine ointment for treating the burn and scald disease is used for treating, eschar is formed on both hands after 10 days of treatment, slough is gradually separated and shed, granulation is ruddy, tissue regeneration and granulation are good, and the wounded facial muscle is full and ruddy and scar is not obvious. In the treatment process, the ten fingers are afraid of pain, bending and non-expansion due to isolation and bandaging, the ten fingers cannot bend and stretch to take articles, the patient goes to a delay and safety hospital for correction operation in the second year, and the patient is not affected after going to school writing.
Clinical application conditions 2
Yanchuan Tuo is seen in Chuancun, farmers are 40 years old, the right leg of the diesel oil burn extends to the foot when the neighbors do bereau, then the people live in Yanchuan TCM hospitals for 30 days, the external application is a moist burn ointment, the internal application is an anti-inflammatory tablet and an infusion are used for anti-infection, the wound is cleared and wound seepage and wound surface are not good and have little swelling, afterwards, the people in our clinics clear and externally apply the traditional Chinese medicine ointment for treating the burn and scald disease for 2 times a day, and the people are cured and get home after 10 days.
Clinical use conditions three
Yanchuan Guo Jia river village farmers, female 22 years old, Lizhi, have epilepsy for many years, have epileptic seizures unconscious at a moment when cooking, have right hands held in the heated kang of a stove, after the family knows, have pulled out and all burnt on the side of the forearm of the finger when pulling out, have serious disability, live into regional hospital to treat 10 days and have gone through the coma period in the day, the hospital recommends to do the limb cutting operation, the expense is 10 ten thousand, the family can't pay because of 10 thousand poverty, and the inessential return to Yanchuan to go to the county hospital does not have any treatment. In the clinic of the doctor, the traditional Chinese medicine paste for treating the burn and scald diseases is adopted, wet dressing is carried out, covering is carried out all day long, heat preservation is carried out, blood circulation is facilitated, and decay is removed to promote tissue regeneration. The skin and flesh are separated after 15 days of treatment, the dead skin of the rotten flesh is cut off, the skin, the bones and muscles of the arm and the back of the hand are slightly moistened, the skin and flesh of the ten fingers are atrophied, the wound surface is free of medicine seepage, the bone surface of the 15 days is also treated, the bone surface is found to be fine like small red dots of sand, the bone surface is uniformly distributed, the bone holes grow out, the bone surface grows gradually to grow like beans, the bone surface is connected into a piece of packaging bone to grow tender meat buds, the bone flesh of the wrist is thickened, the packaging of the meat buds is thick, the ten fingers are dry like firewood, and the palm end package is completely dropped after 15 days.
The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention; various modifications and alterations to this invention will become apparent to those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (7)
1. The ointment for treating burns and scalds and the preparation method thereof are characterized by comprising the following substances in parts by weight: 15-25 parts of angelica, 5-15 parts of Chinese taxillus herb, 5-15 parts of rhubarb, 10-20 parts of phellodendron, 7-12 parts of honeysuckle, 20-30 parts of medical beeswax and 40-55 parts of sesame oil.
2. The ointment for treating burns and scalds according to claim 1, which is characterized by comprising the following substances in parts by weight: 18-22 parts of angelica, 8-12 parts of Chinese taxillus herb, 9-13 parts of rhubarb, 13-19 parts of phellodendron, 9-11 parts of honeysuckle, 22-26 parts of medical beeswax and 45-50 parts of sesame oil.
3. The ointment for treating burns and scalds according to claim 1, which is characterized by comprising the following substances in parts by weight: 20 parts of angelica, 11 parts of Chinese taxillus herb, 12 parts of rhubarb, 17 parts of phellodendron, 10 parts of honeysuckle, 23 parts of medical beeswax and 48 parts of sesame oil.
4. The preparation method of the ointment for treating burns and scalds as claimed in claim 1, which is characterized by comprising the following steps:
step 1, weighing 20 parts of angelica, 11 parts of herba taxilli, 12 parts of rheum officinale, 17 parts of phellodendron and 10 parts of honeysuckle according to parts by weight, preferably selecting, slicing and removing impurities, then decocting and extracting twice by using purified water, standing for 1-2 hours, and preserving in another container;
and 2, adding 8-13% of medical beeswax and 55-75% of sesame oil by mass into the substance obtained in the step 1, mixing and heating until the medical beeswax and the sesame oil are fully dissolved, continuously heating and stirring until the liquid does not overflow to form a thick liquid of the glue juice, removing the fire and annealing the gas, and removing the oil and condensing the smoke gas to obtain the ointment for treating the burn and scald.
5. The method for preparing ointment for treating burns and scalds as claimed in claim 4, wherein the purified water boiling temperature is 100 ℃ and the time period is 30-50 minutes.
6. The method for preparing ointment for treating burns and scalds as claimed in claim 4, wherein the heating and stirring are continuous clockwise stirring.
7. The method for preparing ointment for treating burns and scalds as claimed in claim 4, wherein the extraction is performed twice, and the two-layer filtration is performed by 80-100 mesh gauze.
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Application publication date: 20210209 |