CN112295481A - Liquid medicament secondary agitated vessel for bio-pharmaceuticals - Google Patents

Liquid medicament secondary agitated vessel for bio-pharmaceuticals Download PDF

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Publication number
CN112295481A
CN112295481A CN202011075621.8A CN202011075621A CN112295481A CN 112295481 A CN112295481 A CN 112295481A CN 202011075621 A CN202011075621 A CN 202011075621A CN 112295481 A CN112295481 A CN 112295481A
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CN
China
Prior art keywords
stirring
rod
rack
gear
bio
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Pending
Application number
CN202011075621.8A
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Chinese (zh)
Inventor
孟广寻
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Individual
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Individual
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Priority to CN202011075621.8A priority Critical patent/CN112295481A/en
Publication of CN112295481A publication Critical patent/CN112295481A/en
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00Other mixers; Mixing plants; Combinations of mixers
    • B01F33/80Mixing plants; Combinations of mixers
    • B01F33/81Combinations of similar mixers, e.g. with rotary stirring devices in two or more receptacles
    • B01F33/811Combinations of similar mixers, e.g. with rotary stirring devices in two or more receptacles in two or more consecutive, i.e. successive, mixing receptacles or being consecutively arranged
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/05Stirrers
    • B01F27/11Stirrers characterised by the configuration of the stirrers
    • B01F27/19Stirrers with two or more mixing elements mounted in sequence on the same axis
    • B01F27/191Stirrers with two or more mixing elements mounted in sequence on the same axis with similar elements
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/22Mixing of ingredients for pharmaceutical or medical compositions

Abstract

The invention relates to a secondary medicament stirring device, in particular to a secondary liquid medicament stirring device for bio-pharmaceuticals. The invention provides a secondary stirring device for liquid medicament for bio-pharmaceuticals, which can perform secondary stirring and improve the stirring effect. The invention provides a secondary stirring device for liquid medicaments for bio-pharmaceuticals, which comprises: a bottom plate, one side of which is connected with a bottom frame; a charging bucket rack is connected to one side of the underframe; the other side of the underframe is connected with the frame; the stirring component is arranged between the rack and the charging basket rack; mix the material subassembly, install on the storage bucket frame and mix the material subassembly, mix the material subassembly and stir the subassembly transmission and be connected. According to the stirring device, the liquid medicament can be stirred for the first time through the stirring assembly, the liquid medicament can be stirred for the second time through the stirring assembly, and the second stirring rod and the first stirring rod are different in shape, so that the stirring effect can be improved.

Description

Liquid medicament secondary agitated vessel for bio-pharmaceuticals
Technical Field
The invention relates to a secondary medicament stirring device, in particular to a secondary liquid medicament stirring device for bio-pharmaceuticals.
Background
The biopharmaceutical raw materials mainly comprise natural biological materials including microorganisms, human bodies, animals, plants, marine organisms and the like, and different liquid medicaments are often required to be stirred to be mixed in the pharmaceutical process.
Through search, the patent publication numbers are: CN210846075U patent discloses a stirring apparatus, which comprises a stirring cylinder, a stirring device disposed in the stirring cylinder, and a driving device mounted on the upper end of the stirring cylinder, wherein the stirring device comprises a first stirring shaft rotatably disposed at two ends of the stirring cylinder, a second stirring shaft sleeved outside the first stirring shaft and rotatably connected with the bottom wall of the stirring cylinder, gear boxes disposed on the two stirring shafts, bevel gears disposed in the gear boxes, and stirring blades fixedly connected to the two stirring shafts, one end of the second stirring shaft far from the bottom wall penetrates into the gear boxes, the bevel gears comprise a first bevel gear fixedly connected to the first stirring shaft, a second bevel gear fixedly connected to the free end of the second stirring shaft, and a third bevel gear rotatably disposed on the inner side wall of the gear box, and the three bevel gears are mutually matched; the stirring device has the advantages that the stirring efficiency is high, the operation is convenient, and the labor amount of workers is greatly reduced.
Therefore, it is necessary to develop a liquid medicine secondary stirring apparatus for bio-pharmaceuticals, which can perform secondary stirring and can improve the stirring effect.
Disclosure of Invention
(1) Technical problem to be solved
In order to overcome the defect that the stirring effect is not ideal enough because the stirring equipment only has one stirring cylinder and can only perform primary stirring work and the stirring blades are the same, the invention provides the secondary stirring equipment for the liquid medicament for the bio-pharmaceuticals, which can perform secondary stirring and improve the stirring effect.
(2) Technical scheme
In order to solve the above technical problems, the present invention provides a secondary stirring apparatus for liquid drug for bio-pharmaceuticals, comprising: a bottom plate, one side of which is connected with a bottom frame; a charging bucket rack is connected to one side of the underframe; the other side of the underframe is connected with the frame; the stirring component is arranged between the rack and the charging basket rack; mix the material subassembly, install on the storage bucket frame and mix the material subassembly, mix the material subassembly and stir the subassembly transmission and be connected.
Preferably, the stirring assembly comprises: the inner wall of the upper part of the charging basket frame is connected with a first charging basket; the end part of the first mixing barrel is connected with the hopper; the servo motor is arranged on one side of the rack; the servo motor is connected with a rotating shaft; the upper part of the outer side surface of the material barrel frame is connected with the shaft sleeve; the sleeve is connected in the shaft sleeve in a rotating mode; the lower parts of the outer walls of the sleeve and the rotating shaft are connected with driving wheels; the belt is connected between the transmission wheels; the hexagonal rotating rod is connected with the sleeve in a sliding manner; one end of the hexagonal rotating rod is rotatably connected with a pressing rod; the other end of the hexagonal rotating rod is connected with a connecting rod; the end part of the connecting rod is connected with a transmission gear; the first stirring rod is rotatably connected to the first stirring barrel; the end part of the first stirring rod is connected with a first gear, and the first gear is meshed with the transmission gear; the lower part of the first mixing barrel is connected with a feeding pipe; the feeding pipe is provided with a first ball valve.
Preferably, the stirring assembly comprises: the inner wall of the lower part of the material barrel frame is connected with a second material mixing barrel, and the tail end of the feeding pipe is connected with the second material mixing barrel; the second stirring rod is rotatably connected to the second stirring barrel; the end part of the second stirring rod is connected with a second gear which is matched with the transmission gear; the lower part of the second mixing barrel is connected with a discharge pipe; the discharge pipe is provided with a second ball valve; the upper part of the outer side surface of the charging basket frame is connected with a fixed block; the fixed block is connected with a connecting spring; the connecting spring is connected with a loop bar, and the inner wall of the loop bar is rotatably connected with the connecting rod; the top in the machine frame is connected with a connecting plate; the connecting plate is connected with a wedge block in a sliding manner, and the wedge block is matched with the loop bar; the reset spring is connected between the wedge-shaped block and the connecting plate; the wedge-shaped blocks are connected with pull rods.
Preferably, the device further comprises a linkage assembly, wherein the linkage assembly comprises: the other side of the rack is connected with a fixed plate which is connected with a pressure rod in a sliding way; the upper part of the fixed plate is rotatably connected with the connecting rod; one end of the connecting rod and the upper part of the rotating shaft are both connected with bevel gears, and the two bevel gears are meshed; the other end of the connecting rod is connected with the one-way clutch; the poking disc is connected with the poking disc on the one-way clutch and matched with the pressing rod.
Preferably, the method further comprises the following steps: the charging bucket is placed on the other side of the bottom plate.
(3) Advantageous effects
Compared with the prior art, the invention has the beneficial effects that: 1. can carry out a stirring work to liquid medicament through stirring the subassembly, can carry out secondary stirring work to liquid medicament through mixing the material subassembly, and the shape of second puddler and first puddler is different to can improve stirring effect.
2. The linkage subassembly can assist and mix the material subassembly and carry out work, and the charging bucket can be collected liquid medicament.
Drawings
Fig. 1 is a schematic perspective view of the present invention.
Fig. 2 is a schematic partial perspective view of a first embodiment of the present invention.
Fig. 3 is a second partial perspective view of the present invention.
FIG. 4 is a perspective view of the linkage assembly of the present invention.
The labels in the figures are: 1-bottom plate, 2-bottom frame, 3-material barrel frame, 4-frame, 5-stirring component, 51-first material mixing barrel, 52-leakage hopper, 53-servo motor, 54-rotating shaft, 55-shaft sleeve, 56-sleeve, 57-driving wheel, 58-belt, 59-hexagonal rotating rod, 510-pressing rod, 511-connecting rod, 512-driving gear, 513-first stirring rod, 514-first gear, 515-feeding pipe, 516-first ball valve, 6-material mixing component, 61-second material mixing barrel, 62-second stirring rod, 63-second gear, 64-discharging pipe, 65-second ball valve, 66-fixing block, 67-sleeve rod, 68-connecting spring, 69-connecting plate, 610-wedge block, 611-return spring, 612-pull rod, 7-linkage component, 71-fixed plate, 72-connecting rod, 73-bevel gear, 74-one-way clutch, 75-dial plate and 8-charging barrel.
Detailed Description
The invention is further described below with reference to the figures and examples.
Example 1
The utility model provides a liquid medicament secondary agitated vessel for bio-pharmaceuticals, as shown in fig. 1 to 3, including bottom plate 1, chassis 2, storage bucket frame 3, frame 4, stirring subassembly 5 and mix material subassembly 6, 1 top left side of bottom plate is connected with chassis 2, 2 top right sides of chassis are connected with storage bucket frame 3, 2 top left sides of chassis are connected with frame 4, install stirring subassembly 5 between frame 4 and the storage bucket frame 3, install on the storage bucket frame 3 and mix material subassembly 6, it is connected with 5 transmission of stirring subassembly to mix material subassembly 6.
The stirring component 5 comprises a first stirring barrel 51, a leakage hopper 52, a servo motor 53, a rotating shaft 54, a shaft sleeve 55, a sleeve 56, a driving wheel 57, a belt 58, a hexagonal rotating rod 59, a pressure rod 510, a connecting rod 511, a transmission gear 512, a first stirring rod 513, a first gear 514, a feeding pipe 515 and a first ball valve 516, the inner wall of the upper part of the material barrel frame 3 is connected with the first stirring barrel 51, the top of the first stirring barrel 51 is connected with the leakage hopper 52, the left side of the top of the rack 4 is provided with the servo motor 53, the output shaft of the servo motor 53 is connected with the rotating shaft 54 through a coupling, the upper part of the outer side surface of the material barrel frame 3 is connected with the shaft sleeve 55, the sleeve 55 is rotatably connected with the sleeve 56, the lower part of the outer wall of the sleeve 56 and the lower part of the outer wall of the rotating shaft 54 are both connected with the driving wheel 57, the belt, the bottom end of the hexagonal rotating rod 59 is connected with a connecting rod 511, the bottom end of the connecting rod 511 is connected with a transmission gear 512, the first stirring barrel 51 is connected with a first stirring rod 513 in a rotating mode, the bottom end of the first stirring rod 513 is connected with a first gear 514, the first gear 514 is meshed with the transmission gear 512, the lower portion of the first stirring barrel 51 is connected with a feeding pipe 515, and a first ball valve 516 is arranged on the feeding pipe 515.
The stirring component 6 comprises a second stirring barrel 61, a second stirring rod 62, a second gear 63, a discharge pipe 64, a second ball valve 65, a fixed block 66, a loop bar 67, a connecting spring 68, a connecting plate 69, a wedge block 610, a reset spring 611 and a pull rod 612, the inner wall of the lower part of the material barrel frame 3 is connected with the second stirring barrel 61, the bottom end of a feed pipe 515 is connected with the second stirring barrel 61, the second stirring barrel 61 is rotatably connected with the second stirring rod 62, the top end of the second stirring rod 62 is connected with the second gear 63, the second gear 63 is matched with a transmission gear 512, the lower part of the second stirring barrel 61 is connected with the discharge pipe 64, the discharge pipe 64 is provided with the second ball valve 65, the upper part of the outer side surface of the material barrel frame 3 is connected with the fixed block 66, the bottom of the fixed block 66 is connected with the connecting spring 68, the bottom end of the connecting spring 68 is connected with the loop bar 67, the inner wall, the connecting plate 69 is connected with a wedge block 610 in a sliding mode, the wedge block 610 is matched with the sleeve rod 67, a return spring 611 is connected between the wedge block 610 and the connecting plate 69, and the left side face of the wedge block 610 is connected with a pull rod 612.
When stirring is to be performed, different liquid medicines are poured into the first stirring barrel 51 through the funnel 52, the servo motor 53 is started to rotate the rotating shaft 54, the rotating shaft 54 rotates to enable the sleeve 56 to rotate through the driving wheel 57 and the belt 58, the sleeve 56 rotates to drive the hexagonal rotating rod 59 to rotate, the hexagonal rotating rod 59 rotates to drive the connecting rod 511 to rotate, the connecting rod 511 rotates to enable the first stirring rod 513 to rotate through the transmission gear 512 and the first gear 514, the first stirring rod 513 rotates to stir the different liquid medicines in the first stirring barrel 51 to enable the different liquid medicines to be uniformly mixed, after the liquid medicines are stirred once in the first stirring barrel 51, the first ball valve 516 is opened, the liquid medicines flow into the second stirring barrel 61 through the feeding pipe 515, then the pressing rod 510 can be moved downwards to enable the hexagonal rotating rod 59 to move downwards, the hexagonal rotating rod 59 moves downwards to drive the connecting rod 511 to move downwards, the connecting rod 511 moves downwards to drive the sleeve rod 67 and the transmission gear 512 to move downwards, the connecting spring 68 is stretched accordingly, the transmission gear 512 can be meshed with the second gear 63, the sleeve rod 67 moves downwards to enable the wedge block 610 to move leftwards, the return spring 611 stretches accordingly, when the sleeve rod 67 moves downwards to be positioned on the lower side of the wedge block 610, the wedge block 610 can move rightwards to be reset under the action of the return spring 611, the sleeve rod 67 can be fixed, the sleeve rod 67 is prevented from moving upwards to be reset, the transmission gear 512 can be fixed, the transmission gear 512 is meshed with the second gear 63, the rotating shaft 54 rotates to enable the second stirring rod 62 to rotate through the transmission gear 512 and the second gear 63, the second stirring rod 62 rotates to mix liquid medicaments in the second stirring barrel 61, and the second stirring rod 62 is different from the first stirring rod 513 in shape, this enables the liquid chemical to be stirred for the second time, and the stirring effect can be improved. After the second stirring operation is completed, the servo motor 53 is turned off, then the second ball valve 65 can be opened to collect the liquid medicine in the second stirring barrel 61, and then the pull rod 612 is pulled leftwards to move the wedge block 610 leftwards, and the return spring 611 is compressed therewith, so that the connecting rod 511 can be moved upwards to be reset under the action of the connecting spring 68.
Example 2
On the basis of embodiment 1, as shown in fig. 4, the device further comprises a linkage assembly 7, the linkage assembly 7 comprises a fixing plate 71, a connecting rod 72, a bevel gear 73, a one-way clutch 74 and a toggle plate 75, the right rear side of the top of the rack 4 is connected with the fixing plate 71, the fixing plate 71 is connected with a compression bar 510 in a sliding manner, the connecting rod 72 is rotatably connected to the left side of the upper part of the fixing plate 71, the bevel gears 73 are connected to the front ends of the connecting rod 72 and the upper part of the rotating shaft 54, the two bevel gears 73 are meshed, the rear end of the connecting rod 72 is connected with the one-way clutch 74, the toggle plate 75 is.
When the pivot 54 rotates, because one-way clutch 74's effect, the dial 75 can not rotate, when making depression bar 510 remove downwards, control servo motor 53 makes pivot 54 antiport, pivot 54 antiport makes connecting rod 72 forward rotation through bevel gear 73, connecting rod 72 forward rotation drives dial 75 forward rotation, dial 75 forward rotation can make depression bar 510 remove downwards, so need not artifical manual removal depression bar 510 of removing downwards, thereby can be laborsaving, after secondary stirring work is accomplished, it can to close servo motor 53.
As shown in figure 1, the device also comprises a charging bucket 8, and the charging bucket 8 is placed on the right side of the top of the bottom plate 1.
After the second ball valve 65 is opened, the liquid medicine in the second mixing barrel 61 flows into the charging barrel 8 through the discharge pipe 64, so that the liquid medicine can be collected.
The above examples are merely representative of preferred embodiments of the present invention, and the description thereof is more specific and detailed, but not to be construed as limiting the scope of the present invention. It should be noted that, for those skilled in the art, various changes, modifications and substitutions can be made without departing from the spirit of the present invention, and these are all within the scope of the present invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims (5)

1. A liquid medicament secondary mixing equipment for bio-pharmaceuticals, its characterized in that includes:
a bottom plate (1) with one side connected with a bottom frame (2);
a charging barrel rack (3) is connected to one side of the bottom frame (2);
the other side of the chassis (2) is connected with the rack (4);
the stirring component (5) is arranged between the rack (4) and the charging basket rack (3);
mix material subassembly (6), install on storage bucket rack (3) and mix material subassembly (6), mix material subassembly (6) and stir subassembly (5) transmission and be connected.
2. A secondary stirring device of liquid agents for biopharmaceuticals according to claim 1, wherein stirring assembly (5) comprises:
the inner wall of the upper part of the charging basket frame (3) is connected with a first charging basket (51);
the end part of the first stirring barrel (51) is connected with the leakage hopper (52);
the servo motor (53) is arranged on one side of the rack (4);
the rotating shaft (54) is connected to the servo motor (53);
the upper part of the outer side surface of the charging bucket rack (3) is connected with the shaft sleeve (55);
the sleeve (56) is connected in the shaft sleeve (55) in a rotating manner;
the lower part of the outer wall of the sleeve (56) and the lower part of the outer wall of the rotating shaft (54) are connected with a driving wheel (57);
the belt (58) is connected between the transmission wheels (57);
the hexagonal rotating rod (59) is connected with the sleeve (56) in a sliding manner;
one end of the hexagonal rotating rod (59) is rotatably connected with the pressing rod (510);
the other end of the hexagonal rotating rod (59) is connected with the connecting rod (511);
the transmission gear (512) is connected with the end part of the connecting rod (511);
the first stirring rod (513) is rotatably connected to the first stirring barrel (51);
the end part of the first stirring rod (513) is connected with a first gear (514), and the first gear (514) is meshed with the transmission gear (512);
the lower part of the first stirring barrel (51) is connected with the feeding pipe (515);
the first ball valve (516) is arranged on the feeding pipe (515).
3. A secondary stirring device of liquid agents for bio-pharmaceuticals according to claim 2, wherein the stirring assembly (6) comprises:
the inner wall of the lower part of the charging basket frame (3) is connected with the second charging basket (61), and the tail end of the feeding pipe (515) is connected with the second charging basket (61);
the second stirring rod (62) is rotatably connected to the second stirring barrel (61);
the end part of the second stirring rod (62) is connected with a second gear (63), and the second gear (63) is matched with the transmission gear (512);
the lower part of the second material mixing barrel (61) is connected with a material outlet pipe (64);
the second ball valve (65) is arranged on the discharge pipe (64);
the upper part of the outer side surface of the charging bucket rack (3) is connected with the fixed block (66);
the fixed block (66) is connected with a connecting spring (68);
the loop bar (67) is connected to the connecting spring (68), and the inner wall of the loop bar (67) is rotatably connected with the connecting rod (511);
the top in the frame (4) is connected with a connecting plate (69);
the wedge block (610) is connected to the connecting plate (69) in a sliding mode, and the wedge block (610) is matched with the sleeve rod (67);
the reset spring (611) is connected between the wedge block (610) and the connecting plate (69);
the pull rod (612) is connected to the wedge block (610).
4. A secondary stirring device of liquid agent for bio-pharmaceuticals according to claim 3 further comprising a linkage assembly (7), the linkage assembly (7) comprising:
the fixing plate (71) is connected to the other side of the rack (4), and the fixing plate (71) is connected with the pressing rod (510) in a sliding mode;
the upper part of the fixed plate (71) is rotatably connected with the connecting rod (72);
one end of the connecting rod (72) and the upper part of the rotating shaft (54) are both connected with the bevel gears (73), and the two bevel gears (73) are meshed;
the other end of the connecting rod (72) is connected with the one-way clutch (74);
the poking disc (75) is connected with the poking disc (75) on the one-way clutch (74), and the poking disc (75) is matched with the pressure lever (510).
5. The apparatus for secondary stirring of liquid agent for bio-pharmaceuticals according to claim 4, further comprising:
the charging bucket (8) is arranged on the other side of the charging bucket (8) and the bottom plate (1).
CN202011075621.8A 2020-10-10 2020-10-10 Liquid medicament secondary agitated vessel for bio-pharmaceuticals Pending CN112295481A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202011075621.8A CN112295481A (en) 2020-10-10 2020-10-10 Liquid medicament secondary agitated vessel for bio-pharmaceuticals

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Application Number Priority Date Filing Date Title
CN202011075621.8A CN112295481A (en) 2020-10-10 2020-10-10 Liquid medicament secondary agitated vessel for bio-pharmaceuticals

Publications (1)

Publication Number Publication Date
CN112295481A true CN112295481A (en) 2021-02-02

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59166231A (en) * 1983-03-11 1984-09-19 Kiyomatsu Ito Emulsion producer
US20150283524A1 (en) * 2014-04-02 2015-10-08 Taiwan Advanced Nanotech Inc. Stirring device and gear train
CN105114552A (en) * 2015-09-11 2015-12-02 苏州农业职业技术学院 Reciprocating mechanism for fluid control
CN106311035A (en) * 2016-11-21 2017-01-11 郑州搜趣信息技术有限公司 Moveable mixing and stirring device with filtering function
CN109126603A (en) * 2018-09-25 2019-01-04 伍超群 A kind of efficient pharmacy agitating device

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59166231A (en) * 1983-03-11 1984-09-19 Kiyomatsu Ito Emulsion producer
US20150283524A1 (en) * 2014-04-02 2015-10-08 Taiwan Advanced Nanotech Inc. Stirring device and gear train
CN105114552A (en) * 2015-09-11 2015-12-02 苏州农业职业技术学院 Reciprocating mechanism for fluid control
CN106311035A (en) * 2016-11-21 2017-01-11 郑州搜趣信息技术有限公司 Moveable mixing and stirring device with filtering function
CN109126603A (en) * 2018-09-25 2019-01-04 伍超群 A kind of efficient pharmacy agitating device

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
徐都,弘学友,恒文: "《建筑机械液力传动》", 31 August 1985, 中国建筑工业出版社 *

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