CN112273549A - Vitamin premix for breeding pigs and preparation method thereof - Google Patents
Vitamin premix for breeding pigs and preparation method thereof Download PDFInfo
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- CN112273549A CN112273549A CN202011070963.0A CN202011070963A CN112273549A CN 112273549 A CN112273549 A CN 112273549A CN 202011070963 A CN202011070963 A CN 202011070963A CN 112273549 A CN112273549 A CN 112273549A
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- Prior art keywords
- vitamin
- lactobacillus
- premix
- extract
- bifidobacterium
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- 241000282887 Suidae Species 0.000 title claims abstract description 49
- 238000009395 breeding Methods 0.000 title claims abstract description 49
- 230000001488 breeding effect Effects 0.000 title claims abstract description 49
- 235000019742 Vitamins premix Nutrition 0.000 title claims abstract description 36
- 238000002360 preparation method Methods 0.000 title abstract description 12
- 241000186660 Lactobacillus Species 0.000 claims abstract description 65
- 229940039696 lactobacillus Drugs 0.000 claims abstract description 65
- 239000000284 extract Substances 0.000 claims abstract description 58
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims abstract description 42
- 241000186000 Bifidobacterium Species 0.000 claims abstract description 26
- 239000011724 folic acid Substances 0.000 claims abstract description 24
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 claims abstract description 21
- 229960000304 folic acid Drugs 0.000 claims abstract description 21
- 235000019152 folic acid Nutrition 0.000 claims abstract description 21
- 229940088594 vitamin Drugs 0.000 claims abstract description 20
- 229930003231 vitamin Natural products 0.000 claims abstract description 20
- 235000013343 vitamin Nutrition 0.000 claims abstract description 20
- 239000011782 vitamin Substances 0.000 claims abstract description 20
- 229940036811 bone meal Drugs 0.000 claims abstract description 19
- 239000002374 bone meal Substances 0.000 claims abstract description 19
- 241000382455 Angelica sinensis Species 0.000 claims abstract description 18
- 229920001353 Dextrin Polymers 0.000 claims abstract description 18
- 239000004375 Dextrin Substances 0.000 claims abstract description 18
- 235000019425 dextrin Nutrition 0.000 claims abstract description 18
- 239000011716 vitamin B2 Substances 0.000 claims abstract description 18
- 239000011726 vitamin B6 Substances 0.000 claims abstract description 18
- 239000011652 vitamin K3 Substances 0.000 claims abstract description 18
- WHMDKBIGKVEYHS-IYEMJOQQSA-L Zinc gluconate Chemical compound [Zn+2].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O WHMDKBIGKVEYHS-IYEMJOQQSA-L 0.000 claims abstract description 17
- BVTBRVFYZUCAKH-UHFFFAOYSA-L disodium selenite Chemical compound [Na+].[Na+].[O-][Se]([O-])=O BVTBRVFYZUCAKH-UHFFFAOYSA-L 0.000 claims abstract description 17
- 239000011781 sodium selenite Substances 0.000 claims abstract description 17
- 229960001471 sodium selenite Drugs 0.000 claims abstract description 17
- 235000015921 sodium selenite Nutrition 0.000 claims abstract description 17
- 239000011670 zinc gluconate Substances 0.000 claims abstract description 17
- 235000011478 zinc gluconate Nutrition 0.000 claims abstract description 17
- 229960000306 zinc gluconate Drugs 0.000 claims abstract description 17
- 150000003722 vitamin derivatives Chemical class 0.000 claims abstract description 15
- 239000011709 vitamin E Substances 0.000 claims abstract description 12
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims abstract description 8
- 229930003427 Vitamin E Natural products 0.000 claims abstract description 4
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims abstract description 4
- 235000019165 vitamin E Nutrition 0.000 claims abstract description 4
- 229940046009 vitamin E Drugs 0.000 claims abstract description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 32
- 238000003756 stirring Methods 0.000 claims description 20
- 239000004575 stone Substances 0.000 claims description 17
- 238000001035 drying Methods 0.000 claims description 16
- 239000011691 vitamin B1 Substances 0.000 claims description 16
- 239000011647 vitamin D3 Substances 0.000 claims description 16
- 238000002156 mixing Methods 0.000 claims description 15
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims description 10
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 claims description 10
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims description 10
- 235000019155 vitamin A Nutrition 0.000 claims description 10
- 239000011719 vitamin A Substances 0.000 claims description 10
- 229940045997 vitamin a Drugs 0.000 claims description 10
- 241000218588 Lactobacillus rhamnosus Species 0.000 claims description 9
- 238000001816 cooling Methods 0.000 claims description 7
- 239000007788 liquid Substances 0.000 claims description 7
- 230000004048 modification Effects 0.000 claims description 7
- 238000012986 modification Methods 0.000 claims description 7
- 230000001376 precipitating effect Effects 0.000 claims description 7
- 241000901050 Bifidobacterium animalis subsp. lactis Species 0.000 claims description 5
- 241001608472 Bifidobacterium longum Species 0.000 claims description 5
- 229940009289 bifidobacterium lactis Drugs 0.000 claims description 5
- 229940009291 bifidobacterium longum Drugs 0.000 claims description 5
- 241000186016 Bifidobacterium bifidum Species 0.000 claims description 4
- 229940002008 bifidobacterium bifidum Drugs 0.000 claims description 4
- 238000000034 method Methods 0.000 claims 5
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims 1
- 239000009188 angelicae sinensis extract Substances 0.000 claims 1
- 229910052708 sodium Inorganic materials 0.000 claims 1
- 239000011734 sodium Substances 0.000 claims 1
- 235000015097 nutrients Nutrition 0.000 abstract description 10
- 238000010521 absorption reaction Methods 0.000 abstract description 9
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract description 4
- 239000011575 calcium Substances 0.000 abstract description 4
- 229910052791 calcium Inorganic materials 0.000 abstract description 4
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract description 3
- 230000004083 survival effect Effects 0.000 abstract description 3
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract description 2
- 238000013329 compounding Methods 0.000 abstract description 2
- 229910052742 iron Inorganic materials 0.000 abstract description 2
- 239000011573 trace mineral Substances 0.000 abstract description 2
- 235000013619 trace mineral Nutrition 0.000 abstract description 2
- 239000011701 zinc Substances 0.000 abstract description 2
- 229910052725 zinc Inorganic materials 0.000 abstract description 2
- 210000002257 embryonic structure Anatomy 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 9
- 238000012360 testing method Methods 0.000 description 7
- 238000004519 manufacturing process Methods 0.000 description 5
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 description 2
- 208000032843 Hemorrhage Diseases 0.000 description 2
- 208000019255 Menstrual disease Diseases 0.000 description 2
- 206010027514 Metrorrhagia Diseases 0.000 description 2
- 208000034702 Multiple pregnancies Diseases 0.000 description 2
- 208000002193 Pain Diseases 0.000 description 2
- 241000405414 Rehmannia Species 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 239000011616 biotin Substances 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 230000012010 growth Effects 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 229910052500 inorganic mineral Inorganic materials 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 235000010755 mineral Nutrition 0.000 description 2
- 239000011707 mineral Substances 0.000 description 2
- 235000015816 nutrient absorption Nutrition 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 230000035764 nutrition Effects 0.000 description 2
- 230000035935 pregnancy Effects 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000001291 vacuum drying Methods 0.000 description 2
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 description 1
- AZJQQNWSSLCLJN-UHFFFAOYSA-N 2-ethoxyquinoline Chemical compound C1=CC=CC2=NC(OCC)=CC=C21 AZJQQNWSSLCLJN-UHFFFAOYSA-N 0.000 description 1
- 206010000242 Abortion threatened Diseases 0.000 description 1
- 241000125175 Angelica Species 0.000 description 1
- 208000000412 Avitaminosis Diseases 0.000 description 1
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 208000005171 Dysmenorrhea Diseases 0.000 description 1
- 206010013935 Dysmenorrhoea Diseases 0.000 description 1
- 208000012671 Gastrointestinal haemorrhages Diseases 0.000 description 1
- 235000001287 Guettarda speciosa Nutrition 0.000 description 1
- 208000034507 Haematemesis Diseases 0.000 description 1
- 208000000616 Hemoptysis Diseases 0.000 description 1
- 206010021135 Hypovitaminosis Diseases 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 235000019764 Soybean Meal Nutrition 0.000 description 1
- 208000005985 Threatened Abortion Diseases 0.000 description 1
- 229930003451 Vitamin B1 Natural products 0.000 description 1
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 description 1
- 208000031971 Yin Deficiency Diseases 0.000 description 1
- DFPAKSUCGFBDDF-ZQBYOMGUSA-N [14c]-nicotinamide Chemical compound N[14C](=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-ZQBYOMGUSA-N 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 206010000210 abortion Diseases 0.000 description 1
- 231100000176 abortion Toxicity 0.000 description 1
- 239000003674 animal food additive Substances 0.000 description 1
- 230000002924 anti-infective effect Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 230000002457 bidirectional effect Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 235000020958 biotin Nutrition 0.000 description 1
- 229960002685 biotin Drugs 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- -1 compound vitamin Chemical class 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 230000007368 endocrine function Effects 0.000 description 1
- 208000001780 epistaxis Diseases 0.000 description 1
- 235000021112 essential micronutrients Nutrition 0.000 description 1
- 230000008175 fetal development Effects 0.000 description 1
- 210000003754 fetus Anatomy 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 208000035861 hematochezia Diseases 0.000 description 1
- 230000003053 immunization Effects 0.000 description 1
- 238000002649 immunization Methods 0.000 description 1
- 208000000509 infertility Diseases 0.000 description 1
- 230000036512 infertility Effects 0.000 description 1
- 231100000535 infertility Toxicity 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 210000001161 mammalian embryo Anatomy 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000005906 menstruation Effects 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 239000002366 mineral element Substances 0.000 description 1
- 235000006286 nutrient intake Nutrition 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 229940055726 pantothenic acid Drugs 0.000 description 1
- 235000019161 pantothenic acid Nutrition 0.000 description 1
- 239000011713 pantothenic acid Substances 0.000 description 1
- 230000032696 parturition Effects 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000001850 reproductive effect Effects 0.000 description 1
- 210000000582 semen Anatomy 0.000 description 1
- 230000001568 sexual effect Effects 0.000 description 1
- 210000001082 somatic cell Anatomy 0.000 description 1
- 239000004455 soybean meal Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 229960003495 thiamine Drugs 0.000 description 1
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 235000010374 vitamin B1 Nutrition 0.000 description 1
- 239000011715 vitamin B12 Substances 0.000 description 1
- QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 description 1
- 235000005282 vitamin D3 Nutrition 0.000 description 1
- 229940021056 vitamin d3 Drugs 0.000 description 1
- 208000030401 vitamin deficiency disease Diseases 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
- 229940110280 zinc methionine Drugs 0.000 description 1
- CNMFGFBWPBBGKX-SCGRZTRASA-L zinc;(2s)-2-amino-4-methylsulfanylbutanoate Chemical compound [Zn+2].CSCC[C@H](N)C([O-])=O.CSCC[C@H](N)C([O-])=O CNMFGFBWPBBGKX-SCGRZTRASA-L 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
- A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
- A23K10/18—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/20—Animal feeding-stuffs from material of animal origin
- A23K10/26—Animal feeding-stuffs from material of animal origin from waste material, e.g. feathers, bones or skin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/163—Sugars; Polysaccharides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/174—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/28—Silicates, e.g. perlites, zeolites or bentonites
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/30—Oligoelements
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Food Science & Technology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Health & Medical Sciences (AREA)
- Physiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Inorganic Chemistry (AREA)
- Biochemistry (AREA)
- Botany (AREA)
- Mycology (AREA)
- Birds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Fodder In General (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
The invention discloses a vitamin premix for breeding pigs and a preparation method thereof, belonging to the field of feeds. Each 1 kg of premix contains: vitamin A150-18-20g and vitamin B215-40 ten thousand IU and vitamin B6150-315-40 ten thousand IU, 8-20g vitamin E and vitamin K31.2-2g of folic acid, 1.2-5g of folic acid, 10-20 hundred million cfu of lactobacillus, 10-20 hundred million cfu of bifidobacterium, 5-10g of zinc gluconate, 3-5g of sodium selenite, 5-10g of bone meal, 10-20g of folium artemisiae argyi extract, 10-20g of radix rehmanniae preparata extract and 20-40g of angelica sinensis extract; the balance being resistant dextrin. The invention can improve the utilization rate of nutrients and promote the absorption of trace elements such as calcium, iron, zinc and the like, and can promote the absorption of nutrient elements, improve the survival rate of embryos, increase the litter size and the weight of weaned piglets by compounding with high-calcium bone meal, lactobacillus and bifidobacterium.
Description
Technical Field
The invention relates to the field of feeds, in particular to a vitamin premix for breeding pigs and a preparation method thereof.
Background
The vitamin premix is a uniform mixture prepared by one or more vitamins and a carrier diluent according to a certain proportion. Vitamins are essential micronutrients for keeping pigs healthy and ensuring normal growth and reproduction. Through exploration of pig raising production practices in various regions and experimental research of scientific research departments for many years, it is proved that vitamin deficiency in pigs is easily caused by improper proportioning of a compound vitamin formula in pig feed, and thus absorption and metabolism of energy and protein are influenced. In the production performance of the breeding pigs, the breeding is an important function of breeding pigs, and the nutrition is an important factor influencing the breeding functions of somatic cells, sexual organs, endocrine functions, fetal development and the like of the breeding pigs. The reproductive performance of the breeding pigs directly influences the production performance of a pig farm, so the breeding management level of breeding sows is more and more paid attention and concerned by people. At present, most of the vitamins and minerals required by the boar are simply mixed, and the absorption effect is rarely emphasized, so that the loss of the nutrient elements is caused. For example, CN102356826A discloses a compound vitamin premix for pigs and a production process thereof, which mainly comprises vitamin A and vitamin B1Vitamin B2Vitamin B6Vitamin D3Vitamin E, vitamin K3Folic acid, vitamin B12Biotin, nicotinamide, pantothenic acid, antioxidant and ethoxyquinoline. The compound premix feed for the breeding pigs disclosed in the publication No. CN108567049A is prepared by fully mixing vitamin A, vitamin B1, vitamin D3, vitamin E, folic acid, biotin, L-carnitine, fruit extract, zinc methionine, sodium selenite and carrier puffed soybean meal, which are also directly mixed with nutrient elements required by the breeding pigs, and is difficult to improve the absorption of the nutrient elements。
Disclosure of Invention
In order to solve the problems, the invention provides a vitamin premix for breeding pigs, which can promote the absorption of the breeding pigs on nutrient elements and improve the physique of the breeding pigs.
Furthermore, in order to improve the utilization rate of nutrient elements, the invention also provides a preparation method of the vitamin premix for the breeding pigs.
In order to achieve the purpose, the invention is realized by the following technical scheme:
the vitamin premix for breeding pigs contains the following components in 1 kilogram of premix: vitamin A150-18-20g and vitamin B215-40 ten thousand IU and vitamin B6150-315-40 ten thousand IU, 8-20g vitamin E and vitamin K31.2-2g of folic acid, 1.2-5g of folic acid, 10-20 hundred million cfu of lactobacillus, 10-20 hundred million cfu of bifidobacterium, 5-10g of zinc gluconate, 3-5g of sodium selenite, 5-10g of bone meal, 10-20g of folium artemisiae argyi extract, 10-20g of radix rehmanniae preparata extract and 20-40g of angelica sinensis extract; the balance being resistant dextrin.
Furthermore, the vitamin premix for the breeding pigs contains the following components in 1 kg of premix: vitamin A200-300 ten thousand IU and vitamin B18-15g and vitamin B220-30 ten thousand IU and vitamin B6200-300 ten thousand IU and vitamin D325-35 ten thousand IU, vitamin E10-20g, vitamin K31.2-1.5g of folic acid, 1.2-3g of folic acid, 10-20 hundred million cfu of lactobacillus, 15-20 hundred million cfu of bifidobacterium, 8g of zinc gluconate, 5g of sodium selenite, 10g of bone meal, 20g of folium artemisiae argyi extract, 15g of radix rehmanniae preparata extract and 30g of angelica sinensis extract; the balance being resistant dextrin.
Further, the bifidobacteria comprise any one or combination of several of bifidobacterium bifidum, bifidobacterium longum and bifidobacterium lactis.
Further, the lactobacillus is lactobacillus rhamnosus.
The preparation method of the vitamin premix for the pigs comprises the following steps:
(1) modification of lactobacillus: putting lactobacillus into water, adding nanoscale medical stone, stirring at high speed, adsorbing, precipitating, concentrating, and vacuum drying to obtain modified lactobacillus:
(2) mixing vitamin A and vitamin B1Vitamin B2Vitamin B6Vitamin D3Vitamin E, vitamin K3Adding folic acid, modified lactobacillus, bifidobacterium, zinc gluconate, sodium selenite, bone meal, folium artemisiae argyi extract, radix rehmanniae preparata extract, angelica sinensis extract and resistant dextrin into a stirrer, keeping the stirring temperature at 30-35 ℃, fully mixing and stirring at the temperature, cooling and drying to obtain the vitamin premix for the breeding pigs.
Further, the water in the step (1) is warm water with the temperature of 35 ℃, and the solid-to-liquid ratio of the lactobacillus to the water is 1: (5-8).
Preferably, the ratio of lactobacillus to water is 1: 8.
furthermore, the amount of the nano medical stone added in the step (1) is 0.5 to 1 time of the amount of the lactobacillus.
Folium artemisiae argyi: has effects of warming channels, stopping bleeding, dispelling cold, relieving pain, eliminating dampness, and relieving itching. Can be used for treating hematemesis, epistaxis, hemoptysis, hematochezia, metrorrhagia, gestational hemorrhage, menoxenia, dysmenorrhea, threatened abortion, and psychroalgia of heart and abdomen. The folium artemisiae argyi extract is powder obtained by concentrating and drying water extract.
Prepared rhizome of rehmannia: has effects in replenishing blood, nourishing yin, replenishing essence, and replenishing marrow. It can be used for treating blood deficiency, sallow complexion, menoxenia, metrorrhagia, metrostaxis, and kidney yin deficiency. The prepared rehmannia root extract is powder obtained by concentrating and drying water extract.
Chinese angelica: has effects of replenishing blood, regulating menstruation, promoting blood circulation, relieving pain, and loosening bowel to relieve constipation. The angelica extract is powder obtained by concentrating and drying water extract.
The traditional Chinese medicine extract, the folium artemisiae argyi, the angelica sinensis and the radix rehmanniae preparata added in the invention have the effects of fetus protection and multiple pregnancy, and the boar can improve the sperm activity, improve the sperm-egg combination and achieve the effect of multiple pregnancy.
The vitamin premix for the breeding pigs and the preparation method thereof have the beneficial effects that:
(1) in the invention, the resistant dextrin is water-soluble, can improve the utilization rate of nutrients and promote the absorption of trace elements such as calcium, iron, zinc and the like, and can promote the absorption of the nutrient elements by compounding with high-calcium bone meal, lactobacillus and bifidobacterium.
(2) The lactobacillus rhamnosus added in the invention can promote nutrient absorption, improve immunity and anti-infection effect, improve nutrition and promote nutrient absorption and intake. Meanwhile, the nano medical stone is improved, the nano medical stone has large specific surface area and strong adsorbability, contains a large amount of beneficial mineral elements, is mixed and stirred at high speed at the temperature of 30-35 ℃, can enable water-soluble lactobacillus rhamnosus to be fully adsorbed, and can greatly adsorb the lactobacillus in medical stone micropores after vacuum drying at the temperature of less than 40 ℃, so that the loss of the lactobacillus is reduced, the propagation of the lactobacillus in intestinal tracts of breeding pigs is improved, and the absorption of the breeding pigs on nutrient substances is promoted.
(3) The microbial feed additive can be added with microbes to perform bidirectional regulation, improve the metabolism of breeding pigs, is mixed with various vitamins and mineral substances for utilization, can improve the immunity, reduce the symptoms of abortion, infertility and the like caused by stress of sows, can act on the whole physiological process of reproduction, improve the semen quality of boars, improve the embryo survival rate, and increase the litter size and the weight of weaned piglets.
Detailed Description
The present invention will be described in further detail with reference to the following examples.
Example 1
The vitamin premix for breeding pigs contains the following components in 1 kilogram of premix: vitamin A150 ten thousand IU and vitamin B120g of vitamin B215 ten thousand IU and vitamin B6150 ten thousand IU and vitamin D315 ten thousand IU, vitamin E20 g and vitamin K31.2g, 1.2g of folic acid, 10 hundred million cfu of lactobacillus, 20 hundred million cfu of bifidobacterium, 10g of zinc gluconate, 3g of sodium selenite, 5g of bone meal, 10g of folium artemisiae argyi extract, 10g of radix rehmanniae preparata extract and 40g of angelica sinensis extract; the balance being resistant dextrin.
In this example, the lactobacillus was lactobacillus rhamnosus.
In this example, the bifidobacterium was bifidobacterium bifidum.
A preparation method of vitamin premix for breeding pigs comprises the following steps:
(1) modification of lactobacillus: putting lactobacillus into water, wherein the water is warm water with the temperature of 35 ℃, and the solid-liquid ratio of the lactobacillus to the water is 1: 5; adding nanoscale medical stone, stirring at high speed, adsorbing, precipitating, concentrating and drying to obtain modified lactobacillus: wherein the addition amount of the nano medical stone is 0.5 times of the amount of the lactobacillus.
(2) Mixing vitamin A and vitamin B1Vitamin B2Vitamin B6Vitamin D3Vitamin E, vitamin K3Adding folic acid, modified lactobacillus, bifidobacterium, zinc gluconate, sodium selenite, bone meal, folium artemisiae argyi extract, radix rehmanniae preparata extract, angelica sinensis extract and resistant dextrin into a stirrer, keeping the stirring temperature at 35 ℃, fully mixing and stirring at the temperature, cooling and drying to obtain the vitamin premix for the breeding pigs.
Example 2
The vitamin premix for breeding pigs contains the following components in 1 kilogram of premix: 350 ten thousand IU of vitamin A and vitamin B18g, vitamin B240 ten thousand IU and vitamin B6350 ten thousand IU and vitamin D340 ten thousand IU, vitamin E8 g and vitamin K32g, 5g of folic acid, 20 hundred million cfu of lactobacillus, 10 hundred million cfu of bifidobacterium, 5g of zinc gluconate, 5g of sodium selenite, 10g of bone meal, 20g of folium artemisiae argyi extract, 15g of radix rehmanniae preparata extract and 20g of angelica sinensis extract; the balance being resistant dextrin.
In this example, the lactobacillus was lactobacillus rhamnosus.
In this example, the bifidobacterium is bifidobacterium longum.
A preparation method of vitamin premix for breeding pigs comprises the following steps:
(1) modification of lactobacillus: putting lactobacillus into water, wherein the water is warm water with the temperature of 35 ℃, and the solid-liquid ratio of the lactobacillus to the water is 1: 8; adding nanoscale medical stone, stirring at high speed, adsorbing, precipitating, concentrating and drying to obtain modified lactobacillus: wherein the addition amount of the nano medical stone is 1 time of that of the lactobacillus.
(2) Mixing vitamin A and vitamin B1Vitamin B2Vitamin B6Vitamin D3Vitamin E, vitamin K3Adding folic acid, modified lactobacillus, bifidobacterium, zinc gluconate, sodium selenite, bone meal, folium artemisiae argyi extract, radix rehmanniae preparata extract, angelica sinensis extract and resistant dextrin into a stirrer, keeping the stirring temperature at 30 ℃, fully mixing and stirring at the temperature, cooling and drying to obtain the vitamin premix for the breeding pigs.
Example 3
The vitamin premix for breeding pigs contains the following components in 1 kilogram of premix: vitamin A200 ten thousand IU and vitamin B115g of vitamin B220 ten thousand IU and vitamin B6200 ten thousand IU and vitamin D325 ten thousand IU, vitamin E10g and vitamin K31.5g, 3g of folic acid, 15 hundred million cfu of lactobacillus, 15 hundred million cfu of bifidobacterium, 5g of zinc gluconate, 5g of sodium selenite, 10g of bone meal, 15g of folium artemisiae argyi extract, 20g of radix rehmanniae preparata extract and 30g of angelica sinensis extract; the balance being resistant dextrin.
In this example, the lactobacillus was lactobacillus rhamnosus.
In this example, the bifidobacteria were a mixture of bifidobacterium longum and bifidobacterium lactis at a ratio of 2: 1.
A preparation method of vitamin premix for breeding pigs comprises the following steps:
(1) modification of lactobacillus: putting lactobacillus into water, wherein the water is warm water with the temperature of 35 ℃, and the solid-liquid ratio of the lactobacillus to the water is 1: 6; adding nanoscale medical stone, stirring at high speed, adsorbing, precipitating, concentrating and drying to obtain modified lactobacillus: wherein the addition amount of the nano medical stone is 0.8 times of the amount of the lactobacillus.
(2) Mixing vitamin A and vitamin B1Vitamin B2Vitamin B6Vitamin D3Vitamin E, vitamin K3Folic acid, modified lactobacillus, bifidobacterium, zinc gluconate, sodium selenite,Adding the bone meal, the folium artemisiae argyi extract, the radix rehmanniae preparata extract, the angelica sinensis extract and the resistant dextrin into a stirrer, keeping the stirring temperature at 35 ℃, fully mixing and stirring at the temperature, cooling and drying to obtain the vitamin premix for the breeding pigs.
Example 4
The vitamin premix for breeding pigs contains the following components in 1 kilogram of premix: vitamin A300 ten thousand IU and vitamin B115g of vitamin B230 ten thousand IU and vitamin B6300 ten thousand IU and vitamin D335 ten thousand IU, vitamin E20 g and vitamin K31.2g, 2g of folic acid, 20 hundred million cfu of lactobacillus, 20 hundred million cfu of bifidobacterium, 8g of zinc gluconate, 5g of sodium selenite, 10g of bone meal, 20g of folium artemisiae argyi extract, 15g of radix rehmanniae preparata extract and 30g of angelica sinensis extract; the balance being resistant dextrin.
In this example, the lactobacillus was lactobacillus rhamnosus.
In this example, the bifidobacteria were a mixture of bifidobacterium bifidum, bifidobacterium longum and bifidobacterium lactis at a ratio of 1:2: 1.
A preparation method of vitamin premix for breeding pigs comprises the following steps:
(1) modification of lactobacillus: putting lactobacillus into water, wherein the water is warm water with the temperature of 35 ℃, and the solid-liquid ratio of the lactobacillus to the water is 1: 5; adding nanoscale medical stone, stirring at high speed, adsorbing, precipitating, concentrating and drying to obtain modified lactobacillus: wherein the addition amount of the nano medical stone is 0.5 times of the amount of the lactobacillus.
(2) Mixing vitamin A and vitamin B1Vitamin B2Vitamin B6Vitamin D3Vitamin E, vitamin K3Adding folic acid, modified lactobacillus, bifidobacterium, zinc gluconate, sodium selenite, bone meal, folium artemisiae argyi extract, radix rehmanniae preparata extract, angelica sinensis extract and resistant dextrin into a stirrer, keeping the stirring temperature at 35 ℃, fully mixing and stirring at the temperature, cooling and drying to obtain the vitamin premix for the breeding pigs.
Example 5
Vitamin premix for breeding pigs, 1 per doseThe kilogram premix contains: vitamin A300 ten thousand IU and vitamin B115g of vitamin B230 ten thousand IU and vitamin B6300 ten thousand IU and vitamin D335 ten thousand IU, vitamin E20 g and vitamin K31.2g, 2g of folic acid, 20 hundred million cfu of lactobacillus, 20 hundred million cfu of bifidobacterium, 8g of zinc gluconate, 5g of sodium selenite, 10g of bone meal, 15g of folium artemisiae argyi extract, 15g of radix rehmanniae preparata extract and 30g of angelica sinensis extract; the balance being resistant dextrin.
In this example, the lactobacillus was lactobacillus rhamnosus.
In this example, the bifidobacterium is bifidobacterium lactis.
A preparation method of vitamin premix for breeding pigs comprises the following steps:
(1) modification of lactobacillus: putting lactobacillus into water, wherein the water is warm water with the temperature of 35 ℃, and the solid-liquid ratio of the lactobacillus to the water is 1: 6; adding nanoscale medical stone, stirring at high speed, adsorbing, precipitating, concentrating and drying to obtain modified lactobacillus: wherein the addition amount of the nano medical stone is 0.8 times of the amount of the lactobacillus.
(2) Mixing vitamin A and vitamin B1Vitamin B2Vitamin B6Vitamin D3Vitamin E, vitamin K3Adding folic acid, modified lactobacillus, bifidobacterium, zinc gluconate, sodium selenite, bone meal, folium artemisiae argyi extract, radix rehmanniae preparata extract, angelica sinensis extract and resistant dextrin into a stirrer, keeping the stirring temperature at 35 ℃, fully mixing and stirring at the temperature, cooling and drying to obtain the vitamin premix for the breeding pigs.
Test examples
1. Test time
Time: : from 18 days 5 and 8 months in 2019 (during non-pregnant period) to 25 days 8 and 2020 (during 90 days of pregnancy), the piglets were fed for 100 days, and the farrowing of each sow was recorded until the piglets were born.
2. Test method
120 nonpregnant sows were randomly selected and divided into 6 groups of 20, the 1 st group being a control group and the 2 nd to 6 th groups being test groups.
3. Feeding management
The sow feeding and immunization are carried out according to conventional feeding management. The daily ration for feeding the sows is the conventional basal daily ration for the sows, and the compound premix for the sows in the examples 1-5 is added to the test group on the basis of the conventional daily ration according to the feed standard of 1 g/kg. Feeding is properly carried out according to the pregnancy period and the body condition of the sow so as to ensure the fat condition of the sow.
4. Measurement items
And (3) comparing and observing the development conditions of mammary tissues of the pregnant sows of the test group and the control group in the later period of the test, and respectively recording the total farrowing number, the live farrowing number and the dead piglet number of the test group and the control group in parturition. And (5) observing uniformity of the piglets.
The results obtained are shown in the following table:
as can be seen from the above table: the experimental group (namely the invention) has high farrowing amount, high coarse survival rate, rapid growth and breeding of later-stage piglets, less morbidity of sows after production, good physical function and strong restorability. And only 1g of the premix can be added into every kilogram of feed to achieve good effect, which shows that the premix has high absorptivity.
The technical solutions provided by the embodiments of the present invention are described in detail above, and the principles and embodiments of the present invention are explained herein by using specific examples, and the descriptions of the embodiments are only used to help understanding the principles of the embodiments of the present invention; meanwhile, for a person skilled in the art, according to the embodiments of the present invention, there may be variations in the specific implementation manners and application ranges, and in summary, the content of the present description should not be construed as a limitation to the present invention.
Claims (7)
1. The vitamin premix for breeding pigs is characterized in that: each 1 kg of premix contains: vitamin A150-18-20g and vitamin B215-40 ten thousand IU and vitamin B6150-315-40 ten thousand IU and vitaminE8-20 g, vitamin K31.2-2g of folic acid, 1.2-5g of folic acid, 10-20 hundred million cfu of lactobacillus, 10-20 hundred million cfu of bifidobacterium, 5-10g of zinc gluconate, 3-5g of sodium selenite, 5-10g of bone meal, 10-20g of folium artemisiae argyi extract, 10-20g of radix rehmanniae preparata extract and 20-40g of angelica sinensis extract; the balance being resistant dextrin.
2. The vitamin premix for breeding pigs according to claim 1, which is characterized in that: each 1 kg of premix contains: vitamin A200 + 300 ten thousand IU, vitamin B18-15g and vitamin B220-30 ten thousand IU and vitamin B6200-300 ten thousand IU and vitamin D325-35 ten thousand IU, 10-20g vitamin E, vitamin K31.2-1.5g of folic acid, 1.2-3g of folic acid, 10-20 hundred million cfu of lactobacillus, 15-20 hundred million cfu of bifidobacterium, 8g of zinc gluconate, 5g of sodium selenite, 10g of bone meal, 20g of folium artemisiae argyi extract, 15g of radix rehmanniae preparata extract and 30g of angelica sinensis extract; the balance being resistant dextrin.
3. The vitamin premix for breeding pigs according to claim 1, which is characterized in that: the Bifidobacterium comprises one or more of Bifidobacterium bifidum, Bifidobacterium longum and Bifidobacterium lactis.
4. The method for preparing the vitamin premix for the breeding pigs according to claim 1, which is characterized in that: the lactobacillus is lactobacillus rhamnosus.
5. A method for preparing the vitamin premix for the breeding pigs according to any one of claims 1 to 4, which is characterized by comprising the following steps: the method comprises the following steps:
(1) modification of lactobacillus: putting lactobacillus into water, adding nanoscale medical stone, stirring at high speed, adsorbing, precipitating, concentrating and drying to obtain modified lactobacillus:
(2) mixing vitamin A and vitamin B1Vitamin B2Vitamin B6Vitamin D3Vitamin E, vitamin K3Folic acid, modified lactobacillus, bifidobacterium, zinc gluconate and selenious acidAdding sodium, bone meal, folium Artemisiae Argyi extract, radix rehmanniae Preparata extract, radix Angelicae sinensis extract and resistant dextrin into a stirrer, maintaining stirring temperature at 30-35 deg.C, mixing thoroughly at this temperature, cooling and drying to obtain vitamin premix for breeding pigs.
6. The method for preparing the vitamin premix for the breeding pigs according to claim 5, which is characterized in that: the water in the step (1) is warm water with the temperature of 35 ℃, and the solid-to-liquid ratio of the lactobacillus to the water is 1: (5-8).
7. The method for preparing the vitamin premix for the breeding pigs according to claim 5, which is characterized in that: the amount of the nano medical stone added in the step (1) is 0.5 to 1 time of the amount of the lactobacillus.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN114631595A (en) * | 2022-04-18 | 2022-06-17 | 江苏恒丰强生物技术有限公司 | Veterinary composite microecological preparation and preparation method and application thereof |
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| CN102204645A (en) * | 2011-06-22 | 2011-10-05 | 武汉回盛生物科技有限公司 | Compound premixed feed for breeding pigs and preparation method thereof |
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| CN101735962A (en) * | 2008-11-12 | 2010-06-16 | 中国农业大学 | Low temperature fermentation inoculum for preparing straw feed |
| CN102204645A (en) * | 2011-06-22 | 2011-10-05 | 武汉回盛生物科技有限公司 | Compound premixed feed for breeding pigs and preparation method thereof |
| CN102987116A (en) * | 2012-10-08 | 2013-03-27 | 安徽长风农牧科技有限公司 | Feed additive for improving reproductive performance of multiparous sow |
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