CN112206249A - Medicine for treating female alopecia and preparation method thereof - Google Patents
Medicine for treating female alopecia and preparation method thereof Download PDFInfo
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- CN112206249A CN112206249A CN202011089260.2A CN202011089260A CN112206249A CN 112206249 A CN112206249 A CN 112206249A CN 202011089260 A CN202011089260 A CN 202011089260A CN 112206249 A CN112206249 A CN 112206249A
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- seed oil
- vitamin
- squeezing
- stirring
- blackcurrant
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- 229940079593 drug Drugs 0.000 title description 4
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- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims abstract description 36
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- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
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Abstract
The invention provides a preparation method of a medicine for treating female alopecia, which comprises the following steps: preparing black currant seed oil; preparing pumpkin seed oil; pouring the obtained blackcurrant seed oil and pumpkin seed oil into a stirring barrel; injecting cod liver oil into a stirring barrel, and stirring to obtain a mixture of black currant seed oil, pumpkin seed oil and cod liver oil; adding vitamin C, vitamin E and vitamin B6 into a stirring barrel, and stirring for 30-65 minutes; adding cystine into a stirring barrel, and stirring for ten minutes; the medicine for treating alopecia is obtained. The pharmaceutical composition has ideal treatment effect on various alopecia, and the alopecia is not easy to relapse after the pharmaceutical composition is used for treatment, so the pharmaceutical composition is suitable for various alopecia patients and is very suitable for the current clinical requirements.
Description
Technical Field
The invention relates to the technical field of medicines or health-care products for treating alopecia, in particular to a medicine for treating female alopecia and a preparation method thereof.
Background
Alopecia refers to abnormal or excessive hair loss, i.e. pathological alopecia. The alopecia is caused by a plurality of reasons, including androgen abnormality, genetic factors, mental trauma, endocrine dyscrasia, body malnutrition, metabolism abnormality, blood vessel dysfunction, mechanical stimulation, exposure to radioactive substances, chemical factors, pathogen infection, certain systemic or local diseases, developmental defects, seasonal alopecia and the like.
The treatment for alopecia mainly comprises means of oral hormone treatment, hair planting, nutrition enhancement and the like. In recent years, researches show that substances such as saw palmetto fruits, biotin and the like have certain therapeutic effects on alopecia, however, some products prepared by the components have unsatisfactory effects on alopecia treatment.
Disclosure of Invention
The invention provides a medicine for treating female alopecia and a preparation method thereof, which are used for improving the alopecia treatment effect and reducing the relapse or aggravation of alopecia.
The invention provides a preparation method of a medicine for treating female alopecia, which comprises the following steps:
preparing black currant seed oil;
preparing pumpkin seed oil;
pouring the obtained blackcurrant seed oil and pumpkin seed oil into a stirring barrel;
injecting cod liver oil into a stirring barrel, and stirring to obtain a mixture of black currant seed oil, pumpkin seed oil and cod liver oil;
adding vitamin C, vitamin E and vitamin B6 into a stirring barrel, and stirring for 30-65 minutes;
adding cystine into a stirring barrel, and stirring for ten minutes; the medicine for treating alopecia is obtained.
Preferably, the step of injecting the cod liver oil into the mixing tank and mixing the cod liver oil to obtain the mixture of the blackcurrant seed oil, the pumpkin seed oil and the cod liver oil further comprises the following steps:
and opening the stirring barrel refrigeration mechanism, and refrigerating the mixture in the stirring barrel by using the stirring barrel refrigeration mechanism.
Preferably, the preparation of blackcurrant seed oil further comprises the steps of:
taking mature blackcurrant fruits, removing blackcurrant pulp, and reserving blackcurrant seeds;
screening out the blackcurrant seeds with uniform size and full particles by using a material selecting machine, and cleaning the blackcurrant seeds by using a cleaning mechanism;
crushing the cleaned blackcurrant seeds by using a crusher;
pouring the crushed blackcurrant seeds into a squeezing barrel, starting a squeezing mechanism, and squeezing the blackcurrant seeds to obtain blackcurrant seed oil.
Preferably, the preparation of the pumpkin seed oil comprises the following steps:
selecting full pumpkin seeds;
peeling with a decorticator to obtain pumpkin kernels;
crushing the pumpkin kernels by using a crusher;
and pouring the crushed pumpkin kernels into a squeezing barrel, starting a squeezing mechanism, and squeezing the pumpkin kernels to obtain the pumpkin seed oil.
Preferably, the medicament for treating female alopecia is prepared according to the following medicinal components:
black currant seed oil: 300 and 630 mg;
cod liver oil: 410 and 580 mg;
pumpkin seed oil: 320-550 mg;
lycopene: 0.6-2.3 mg;
vitamin C: 22-38 mg;
vitamin E: 12-26 mg;
vitamin B6: 0.2-0.8 mg;
cystine: 20-48 mg.
Preferably, the medicament for treating female alopecia is prepared according to the following medicinal components:
black currant seed oil: 400 mg;
cod liver oil: 428 mg;
pumpkin seed oil: 436 mg;
lycopene: 0.9 mg;
vitamin C: 26 mg of the total weight of the composition;
vitamin E: 15 mg;
vitamin B6: 0.3 mg;
cystine: 23 mg.
Preferably, the medicament for treating female alopecia is prepared according to the following medicinal components:
black currant seed oil: 450 mg;
cod liver oil: 450 mg;
pumpkin seed oil: 400 mg;
lycopene: 1 mg;
vitamin C: 30 mg;
vitamin E: 15 mg;
vitamin B6: 0.6 mg;
cystine: 42 mg.
Preferably, a stirring mechanism is erected above the stirring barrel, and a feeding hole and a discharging hole are arranged on the side wall of the stirring barrel at intervals;
a feed port of the stirring barrel is connected with the squeezing barrel;
the upper portion of squeezing the bucket erects presses the mechanism, the below of squeezing the bucket is equipped with the filter, the feed inlet of agitator passes through the pipe connection the below oil-out of squeezing the bucket.
The invention has the following beneficial effects:
tests prove that the pharmaceutical composition has ideal treatment effect on various alopecia, and the alopecia is not easy to relapse after the pharmaceutical composition is used for treatment, so that the pharmaceutical composition is suitable for various alopecia patients and is very suitable for the current clinical requirements.
Additional features and advantages of the invention will be set forth in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention. The objectives and other advantages of the invention will be realized and attained by the structure particularly pointed out in the written description and drawings.
The technical solution of the present invention is further described in detail by the accompanying drawings and embodiments.
Drawings
The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the principles of the invention and not to limit the invention. In the drawings:
FIG. 1 is a flow chart of a preparation method of the present invention;
FIG. 2 is a schematic view of the connecting structure of the press barrel and the mixing barrel of the present invention;
FIG. 3 is a schematic view of a connecting structure of a pulverizing barrel and a press barrel according to the present invention;
FIG. 4 is a schematic view of a connection structure of a third shaft and a fourth shaft according to the present invention;
FIG. 5 is a schematic view of the driving mechanism of the present invention;
FIG. 6 is a perspective view of the cooling mechanism of the present invention;
FIG. 7 is a schematic view of the connection structure of the cooling mechanism and the mixing tank according to the present invention;
FIG. 8 is a schematic diagram of the trigger key structure of the present invention;
wherein, 1-a crushing barrel, 2-a squeezing barrel, 3-a stirring barrel, 4-a communication pipeline, 5-a first rotating shaft, 6-a first bracket, 7-a squeezing rod, 8-a first pressing plate, 9-a squeezing ball, 10-a second pressing plate, 11-a squeezing plate and 12-a supporting leg,
13-a first connecting rod, 14-a second connecting rod, 15-a fixed block, 16-a first movable groove, 17-a first baffle, 18-a first spring, 19-a first U-shaped frame, 20-a first mounting plate, 21-a second rotating shaft, 22-a bent elastic sheet, 23-a clamping block, 24-a limiting block, 25-a rotating disc and 26-a third rotating shaft,
27-a bottom plate, 28-a second U-shaped frame, 29-a connecting plate, 30-a third U-shaped frame, 31-a column, 32-a fourth U-shaped frame, 33-a storage tank, 34-an L connecting rod, 35-a movable barrel, 36-a second baffle, 37-a sealing plate, 38-a pressing block, 39-a pressing rod, 40-a second spring, 41-a third connecting rod, 42-a fourth connecting rod, 43-a fifth U-shaped frame, 44-a fifth rotating shaft, 45-a fifth connecting rod, 46-a sixth U-shaped frame, 47-a seventh connecting rod and 48-a linear driver,
49-a first clamping groove, 50-L elastic sheet, 51-a second mounting plate, 52-a support frame, 53-a third mounting plate, 54-a stirring shaft, 55-a fourth rotating shaft, 56-a bevel gear, 57-a motor, 58-a crushing cutter,
59-sealing cover, 60-third spring, 61-cooling pipe, 62-cooling cavity, 63-second support, 64-trigger key.
Detailed Description
The preferred embodiments of the present invention will be described in conjunction with the accompanying drawings, and it will be understood that they are described herein for the purpose of illustration and explanation and not limitation.
According to the drawings 1-8, the invention provides a preparation method of a medicine for treating female alopecia, which comprises the following steps:
preparing black currant seed oil;
preparing pumpkin seed oil;
pouring the obtained blackcurrant seed oil and pumpkin seed oil into a stirring barrel;
injecting cod liver oil into a stirring barrel, and stirring to obtain a mixture of black currant seed oil, pumpkin seed oil and cod liver oil;
adding vitamin C, vitamin E and vitamin B6 into a stirring barrel, and stirring for 30-65 minutes;
adding cystine into a stirring barrel, and stirring for ten minutes; the medicine for treating alopecia is obtained.
The invention has the following beneficial effects:
tests prove that the pharmaceutical composition has ideal treatment effect on various alopecia, and the alopecia is not easy to relapse after the pharmaceutical composition is used for treatment, so that the pharmaceutical composition is suitable for various alopecia patients and is very suitable for the current clinical requirements.
Preferably, the step of injecting the cod liver oil into the mixing tank and mixing the cod liver oil to obtain the mixture of the blackcurrant seed oil, the pumpkin seed oil and the cod liver oil further comprises the following steps:
and opening the stirring barrel refrigeration mechanism, and refrigerating the mixture in the stirring barrel by using the stirring barrel refrigeration mechanism.
Preferably, the preparation of blackcurrant seed oil further comprises the steps of:
taking mature blackcurrant fruits, removing blackcurrant pulp, and reserving blackcurrant seeds;
screening out the blackcurrant seeds with uniform size and full particles by using a material selecting machine, and cleaning the blackcurrant seeds by using a cleaning mechanism;
crushing the cleaned blackcurrant seeds by using a crusher;
pouring the crushed blackcurrant seeds into a squeezing barrel, starting a squeezing mechanism, and squeezing the blackcurrant seeds to obtain blackcurrant seed oil.
Preferably, the preparation of the pumpkin seed oil comprises the following steps:
selecting full pumpkin seeds;
peeling with a decorticator to obtain pumpkin kernels;
crushing the pumpkin kernels by using a crusher;
and pouring the crushed pumpkin kernels into a squeezing barrel, starting a squeezing mechanism, and squeezing the pumpkin kernels to obtain the pumpkin seed oil.
Preferably, the medicament for treating female alopecia is prepared according to the following medicinal components:
black currant seed oil: 300 and 630 mg;
cod liver oil: 410 and 580 mg;
pumpkin seed oil: 320-550 mg;
lycopene: 0.6-2.3 mg;
vitamin C: 22-38 mg;
vitamin E: 12-26 mg;
vitamin B6: 0.2-0.8 mg;
cystine: 20-48 mg.
Example 1
The medicine for treating female alopecia is prepared according to the following steps:
preparing black currant seed oil;
preparing pumpkin seed oil;
pouring the obtained blackcurrant seed oil and pumpkin seed oil into a stirring barrel;
injecting cod liver oil into a stirring barrel, and stirring to obtain a mixture of black currant seed oil, pumpkin seed oil and cod liver oil;
adding vitamin C, vitamin E and vitamin B6 into a stirring barrel, and stirring for 30-65 minutes;
adding cystine into a stirring barrel, and stirring for ten minutes; the medicine for treating alopecia is obtained.
The medicine for treating female alopecia is prepared from the following medicinal components:
black currant seed oil: 400 mg; cod liver oil: 428 mg;
pumpkin seed oil: 436 mg; lycopene: 0.9 mg;
vitamin C: 26 mg of the total weight of the composition; vitamin E: 15 mg;
vitamin B6: 0.3 mg; cystine: 23 mg.
Example 2
The medicine for treating female alopecia is prepared according to the following steps:
preparing black currant seed oil;
preparing pumpkin seed oil;
pouring the obtained blackcurrant seed oil and pumpkin seed oil into a stirring barrel;
injecting cod liver oil into a stirring barrel, and stirring to obtain a mixture of black currant seed oil, pumpkin seed oil and cod liver oil;
adding vitamin C, vitamin E and vitamin B6 into a stirring barrel, and stirring for 30-65 minutes;
adding cystine into a stirring barrel, and stirring for ten minutes; the medicine for treating alopecia is obtained.
The medicine for treating female alopecia is prepared from the following medicinal components:
black currant seed oil: 450 mg; cod liver oil: 450 mg;
pumpkin seed oil: 400 mg; lycopene: 1 mg;
vitamin C: 30 mg; vitamin E: 15 mg;
vitamin B6: 0.6 mg; cystine: 42 mg.
Clinical trial
Case selection and grouping
90 alopecia patients were randomized into 3 groups: examples 1-2 groups and a commercial product, 30 each.
No statistical difference exists among the age, sex, disease course and alopecia symptom severity degree of each group (p is greater than 0.05).
Second, inclusion criteria
(1) Age 18-65 years old;
(2) meets the clinical diagnosis standard of alopecia;
(3) no other treatments were performed within 1 month prior to the trial;
(4) no other serious visceral diseases.
Exclusion criteria
(1) Alopecia due to developmental defects and genetic factors;
(2) alopecia caused by systemic diseases and the systemic diseases are not cured;
(3) pregnant or lactating women;
(4) patients with allergic history or allergic constitution of the medicinal components;
(5) patients with serious primary diseases such as cardiovascular diseases, liver diseases, kidney diseases or hemopoietic diseases;
(6) patients with mental diseases.
Fourth, the therapeutic method
The medicine corresponding to each test group is orally taken, 0.5g is taken each time, 2 times a day, and 42 days are 1 course of treatment.
Fifth, observation index and therapeutic effect judgment standard
The clinical indexes are as follows: clinical symptoms and sign changes are observed day by day during the test period, and the occurrence time, the expression, the degree, the treatment and the results of various adverse reactions are closely monitored.
Laboratory indexes are as follows: before the test and after stopping the drug, the routine examination of blood, urine and stool, and the function of liver and kidney.
And (3) evaluating and grading the curative effect:
the overall improvement degree according to clinical symptoms and physical signs is divided into four grades:
and (3) healing: clinical symptoms disappear, the hair growth returns to normal, and abnormal or excessive shedding phenomenon does not occur;
the effect is shown: the clinical symptoms are obviously improved, the hair growth is basically normal, and the abnormal or excessive shedding phenomenon is not obvious;
the method has the following advantages: the clinical symptoms are improved, but the normal state is not recovered;
and (4) invalidation: the clinical symptoms are not improved or aggravated.
Observation of recurrence rate: after the administration, the patients with recovery, obvious effect and effective cases follow up for 3 months, and the disease recurrence rate is recorded.
Sixth, therapeutic results
The clinical efficacy and recurrence rate statistics for each test group after 42 days of treatment and 3 months follow-up are shown in table 1 below.
TABLE 1 statistical table of curative effect and recurrence rate of each test group
| Group of | Number of examples | Recovery method | Show effect | Is effective | Invalidation | Total effective rate | Recurrence rate |
| Example 1 | 30 | 7 | 16 | 5 | 2 | 93.3％ | 25％ |
| Example 2 | 30 | 5 | 21 | 2 | 2 | 93.3％ | 14.3％ |
| A certain |
30 | 0 | 0 | 4 | 26 | 13.3％ | 75％ |
As can be seen from table 1, the recovery rate, the significant efficiency and the total effective rate of each example group are significantly higher than those of the comparative example group, and the recurrence rate after treatment is lower, which proves that the pharmaceutical composition of the present invention has long-term therapeutic effect on alopecia.
According to the drawings of fig. 1-8, a stirring mechanism is erected above the stirring barrel 3, and a feeding hole and a discharging hole are arranged on the side wall of the stirring barrel 3 at intervals;
a feed inlet of the stirring barrel 3 is connected with the squeezing barrel 2;
the squeezing mechanism is erected above the squeezing barrel 2, a filtering plate is arranged below the squeezing barrel 2, and a feeding hole of the stirring barrel 3 is connected with a lower oil outlet of the squeezing barrel 2 through a pipeline.
When the device works, the crushing barrel is used for crushing raw materials, then the crushed raw materials are injected into the squeezing barrel through the communicating pipeline, and the crushed raw materials are squeezed to obtain raw material squeezing oil; then, the raw material pressed oil flows into the stirring barrel through a pipeline;
the stirring barrel can be connected with a plurality of squeezing barrels, the purpose that a plurality of raw material squeezed oil can be mixed into the stirring barrel together for stirring is achieved, the stirring barrel can also be provided with a feeding port, and the feeding port is used for sequentially adding cod-liver oil, vitamin C, vitamin E, vitamin B6 and cystine; thereby obtaining the medicine for treating female alopecia.
The method comprises the following specific steps:
the blackcurrant seeds and the pumpkin kernels are simultaneously crushed by two crushing barrels;
respectively injecting the crushed blackcurrant seeds and pumpkin kernels into a squeezing barrel through a communication pipeline;
starting a motor, wherein the motor drives the squeezing mechanism to squeeze blackcurrant seeds and pumpkin kernels in each squeezing barrel respectively to obtain blackcurrant seed oil and pumpkin seed oil respectively;
injecting cod liver oil into the stirring barrel; respectively injecting the blackcurrant seed oil and the pumpkin seed oil in each squeezing barrel into a stirring barrel; mixing and stirring to obtain a mixture of blackcurrant seed oil, pumpkin seed oil and cod liver oil;
adding vitamin C, vitamin E and vitamin B6 into a stirring barrel, and stirring for 30 minutes;
adding cystine into a stirring barrel, and stirring for ten minutes; the medicine for treating alopecia is obtained.
According to the figures 1-8, a plurality of supporting legs 12 are arranged below the crushing barrel 1 at intervals, and one side of the crushing barrel 1 close to the supporting legs 12 is connected with the squeezing barrel 2 through a communication pipeline 4;
one end of the crushing barrel 1, which is far away from the supporting legs 12, is a feeding hole, a first support 6 is erected in the feeding hole of the crushing barrel 1, the first support 6 is rotatably erected with a first rotating shaft 5 through a bearing, and one end of the first rotating shaft 5 extends into the crushing barrel 1 and is connected with a crushing cutter 58;
the other end of the first rotating shaft 5 extends out of the crushing barrel 1 and is connected with a driving mechanism;
a plurality of supporting legs 12 are arranged below the squeezing barrel 2, and the squeezing barrel 2 is arranged on one side of the crushing barrel 1 at intervals; the squeezing barrel 2 is connected with the stirring barrel 3 through a pipeline; a stirring shaft 54 is erected above the stirring barrel 3, one end of the stirring shaft 54, which is positioned inside the stirring barrel 3, is provided with a stirring paddle, and the other end of the stirring shaft 54 is connected with the driving device;
the squeezing mechanism includes: a press bar 7 and a first presser plate 8;
a second support 63 of a U-shaped structure is arranged above the squeezing barrel 2, a motor 57 is arranged at the outer top of the second support 63, the rotating end of the motor 57 penetrates through the second support 63 and extends to the inner top of the U-shaped structure of the second support 63, the rotating end of the motor 57 is connected with a squeezing rod 7, and a first pressing plate 8 and a second pressing plate 10 are arranged at intervals at one end of the squeezing rod 7, which is far away from the second support 63;
a plurality of arc-shaped convex squeezing balls 9 are arranged on one surface of the first pressing plate 8 close to the second pressing plate 10 at intervals, and a plurality of squeezing plates 11 are arranged on one surface of the second pressing plate 10 far away from the first pressing plate 8 at intervals;
the driving device includes: a rotary plate 25 and a first link 13,
a first connecting rod 13 is connected to the outer wall of the squeezing rod 7, and the first connecting rod 13 is positioned between the second bracket 63 and the first pressing plate 8; the other end of the first connecting rod 13 is connected with a second connecting rod 14, the squeezing rod 7, the first connecting rod 13 and the second connecting rod 14 form a U-shaped structure, and the first connecting rod 13 extends out of the squeezing barrel 2;
a fixed block 15 is arranged on the outer wall of the squeezing barrel 2, a first movable groove 16 is arranged on one surface, far away from the squeezing barrel 2, of the fixed block 15, and the fixed block 15 is movably connected with the second connecting rod 14; one end of the second connecting rod 14, which is far away from the first connecting rod 13, is connected with a first U-shaped frame 19, and a U-shaped opening end of the first U-shaped frame 19 is rotatably connected with a clamping block 23 through a second rotating shaft 21;
a first spring 18 is sleeved on the second connecting rod 14, the first spring 18 is positioned in the first movable groove 16, and a first baffle 17 is arranged at one end of the first spring 18 close to the first connecting rod 13;
a first mounting plate 20 is mounted on one side of the first U-shaped frame 19, a bent elastic sheet 22 is connected to the first mounting plate 20 close to the U-shaped opening end of the first U-shaped frame 19, and an angle between the bent elastic sheet 22 and the first mounting plate 20 is an obtuse angle;
the stirring mechanism comprises a stirring shaft and a stirring paddle;
a rotating disc 25 is arranged on one side of the clamping block 23 away from the bent elastic sheet 22, one side of the rotating disc 25 is connected with a fourth rotating shaft 55, and the fourth rotating shaft 55 is meshed with the stirring shaft 54 through a bevel gear 56 and is used for driving the stirring paddle to rotate by the stirring shaft 54;
a limit block 24 is arranged on one side of the turntable 25, which is far away from the fourth rotating shaft 55, the limit block 24 is of a square structure, L-shaped elastic pieces 50 of an L structure are respectively arranged on two sides of the limit block 24, an L opening of each L-shaped elastic piece is arranged on one side, which is far away from the limit block 24, and the L-shaped elastic pieces 50 are respectively arranged on the second mounting plates 51 at intervals; one end of the limiting block 24 far away from the turntable 25 is connected with a third rotating shaft 26;
a plurality of first clamping grooves 49 are uniformly distributed on the circumferential outer wall of the rotating disc 25 at intervals, and the first clamping grooves 49 are matched with one ends of the clamping blocks 23 far away from the first U-shaped frame 19;
the two sides of the second mounting plate 51 are respectively provided with a third mounting plate 53, one end of the third mounting plate 53, which is far away from the second mounting plate 51, is respectively connected with a support frame 52, two bearings are respectively penetrated through the two support frames 52, and each bearing is respectively used for rotatably connecting a third rotating shaft 26 and a fourth rotating shaft 55; one end of the third rotating shaft 26 far away from the limiting block 24 is meshed with the first rotating shaft 5 through a bevel gear 56.
The working principle and the beneficial effects of the embodiment are as follows:
when the squeezing mechanism works, firstly, after the motor is started, the motor drives the squeezing rod to move up and down, so that the first pressing plate and the second pressing plate are driven to move up and down in the squeezing barrel, and the purpose of squeezing raw materials in the squeezing barrel by using the first pressing plate and the second pressing plate is achieved;
the squeezing rod can drive the squeezing balls below the first pressing plate to squeeze the raw materials in the process of moving up and down; the second pressing plate enables the pressing plate to be inserted and extended in the raw material in a reciprocating mode to achieve the purpose of loosening the raw material, and the second pressing plate is used for compressing the raw material in a reciprocating mode; the purpose that raw materials in the squeezing barrel are well squeezed is achieved by reciprocating in the way;
the squeezing rod can drive the first connecting rod connected with the outer side wall of the squeezing rod to move up and down in the process of moving up and down;
the first connecting rod can move up and down when moving up and down, the second connecting rod can drive the first U-shaped frame to move up and down when moving up and down, one side of the first U-shaped frame is provided with a V-shaped limiting structure formed by a first mounting plate and a bent elastic sheet, and the V-shaped limiting structure is used for limiting a clamping block rotatably connected to the first U-shaped frame, so that the clamping block can be mutually clamped with first clamping grooves arranged at intervals on a rotary disc at the other side when moving up and down along with the second connecting rod; therefore, the purpose of stirring the rotating disc to rotate is achieved, the rotating disc can drive the third rotating shaft and the fourth rotating shaft to rotate after rotating, and the purpose of driving the stirring mechanism and the crushing mechanism to move together is achieved;
in the rotating process of the turntable, the unidirectional rotation of the turntable is realized by utilizing the L-shaped elastic sheet and the limiting block, so that the condition that the turntable rotates reversely in the rotating process is reduced;
the first spring is used for achieving the purpose that when the second connecting rod moves upwards, the second connecting rod is favorable for driving the first baffle to move upwards.
In one embodiment, the first movable slot 16 is further provided with a trigger key 64, and the trigger key 64 is in contact with a surface of the first baffle 17 away from the first spring 18;
the trigger key 64 is used for turning on or off the refrigeration mechanism;
the refrigeration mechanism includes: the refrigerator comprises a closing mechanism, a storage box 33 and a bottom plate 27, wherein the closing mechanism and the storage box 33 are respectively installed on the bottom plate 27, the storage box 33 is used for storing a refrigeration medium, an opening is formed above the storage box 33, and a sealing cover 59 is buckled on the opening; a cooling pipeline 61 is connected to the outer side of the sealing cover 59;
a cooling cavity 62 is formed in the inner wall of the stirring barrel 3, and the cooling cavity 62 is communicated with the inside of the sealing cover 59 through a cooling pipeline 61;
a sealing plate 37 is arranged between the sealing cover 59 and the storage box 33, and the sealing plate 37 is used for communicating or sealing the sealing cover 59 and the storage box 33;
a second baffle plate 36 is arranged on one surface of the storage box 33 close to the sealing cover 59 at intervals, a third spring 60 is arranged on one surface of the second baffle plate 36 close to the sealing cover 59, and the third spring 60 is used for connecting the sealing plate 37; the closing plate 37 is provided with a closing mechanism on the side thereof remote from the second shutter 36.
The working principle and the beneficial effects of the embodiment are as follows:
the trigger key can move up and down along with the second connecting rod when the first baffle moves up and down, and further the first baffle can intermittently trigger the trigger key, so that the closing mechanism is intermittently closed or opened, and the aim of intermittently opening or closing the storage box by using the closing mechanism is fulfilled;
the storage tank is also provided with an inlet for injecting a cooling medium, preferably nitrogen; the closing mechanism can be intermittent type open or close the bin realizes the discharge that the nitrogen gas of bin can be intermittent type to further arrange via cooling tube the cooling intracavity, the cooling chamber still is equipped with the delivery outlet, the delivery outlet intercommunication the import of bin is used for retrieving cooling chamber exhaust nitrogen gas to save the nitrogen gas energy, improve the nitrogen gas rate of utilization.
In operation, after the closing mechanism is activated, the sealing plate moves from right to left in fig. 7 and closes the communication between the storage tank and the sealing cover, so as to cut off the communication between the storage tank and the cooling pipeline; when needs are opened during the intercommunication of bin and sealed cowling, close closing mechanism, the shrouding loses the roof pressure back, the third spring will promote the shrouding is moved to the left to open the bin with the intercommunication of sealed cowling, thereby the realization is carried the purpose of nitrogen gas to cooling pipeline.
In one embodiment, as shown in fig. 1-8, the closure mechanism comprises: a second U-shaped frame 28, an L-shaped connecting rod 34 and a pressing block 38; the second U-shaped frame 28 is fixed on the bottom plate 27 through a connecting plate 29, the U-shaped open end of the second U-shaped frame 28 is far away from the connecting plate 29, the U-shaped open end of the second U-shaped frame 28 is rotatably connected with a linear driver 48, the driving end of the linear driver 48 is connected with a seventh connecting rod 47, and one end of the seventh connecting rod 47, which is far away from the driving end of the linear driver 48, is connected with the third U-shaped frame 30;
the open end of the third U-shaped frame 30 is far away from the seventh connecting rod 47, and the U-shaped open end of the third U-shaped frame 30 is rotatably connected to the outer wall of the movable cylinder 35 through a rotating shaft;
the outer walls of the two sides of the U-shaped opening end of the third U-shaped frame 30 are respectively and rotatably connected in a U-shaped notch of a sixth U-shaped frame 46;
the movable cylinder 35 is coaxially and movably sleeved on the circumferential outer wall of the third connecting rod 41, one end of the third connecting rod 41 is fixedly connected with the upright column 31, one end of the upright column 31, which is far away from the third connecting rod 41, is rotatably connected to the fourth U-shaped frame 32, one end of the fourth U-shaped frame 32, which is far away from the upright column 31, is fixed on the bottom plate 27 through the connecting plate 29, and the fourth U-shaped frame 32 is positioned between the second U-shaped frame 28 and the storage box 33;
the other end of the third connecting rod 41 is rotatably connected with a pressure sensor, one end of the pressure sensor is connected with a fifth U-shaped frame 43 through a fourth connecting rod 42, the U-shaped opening end of the fifth U-shaped frame 43 is rotatably connected with a fifth connecting rod 45 through a fifth rotating shaft 44, and the other end of the fifth connecting rod 45 is connected with one end, far away from the third lower right corner, of the sixth U-shaped frame 46;
the third connecting rod 41 is sleeved with a second spring 40, one end of the second spring 40 is close to the pressure, and the other end of the second spring 40 is connected with the end part of the movable cylinder 35; a pressing block 38 is arranged at one end of the pressing rod 39 far away from the fourth connecting rod 42, one end of the pressing block 38 far away from the pressing rod 39 is of an arc-shaped structure, and the surface of the arc-shaped structure is used for pressing the upper surface of the sealing plate 37;
one side that stand 31 kept away from second U type frame 28 is connected with the L connecting rod 34 of L structure, the other end of L connecting rod 34 is equipped with the kicking block, the kicking block orientation the lateral surface setting of shrouding 37, just the kicking block supports shrouding 37's lateral surface.
The working principle and the beneficial effects of the embodiment are as follows:
when the closing mechanism works, the triggering key opens or closes the linear driver; when the linear driver is electrified to work, the seventh connecting rod is pushed to move towards the direction of the third U-shaped frame; thereby driving the third U-shaped frame and the sixth U-shaped frame to move; the movable barrel is sleeved on the third connecting rod, so that the third connecting rod can slide on the third connecting rod; the fifth connecting rod drives the fifth U-shaped frame and the third connecting rod to carry out linkage; the straight rod is formed by the fifth U-shaped frame, the third connecting rod and the pressing rod, so that the straight rod is rightwards inclined by taking a part where the third connecting rod is rotatably connected with the pressing rod as a fulcrum, and the pressing block is pressed on the upper surface of the sealing plate;
meanwhile, the third connecting rod can drive the stand column to swing on the fourth U-shaped frame, so that the L-shaped connecting rod on the stand column inclines towards the sealing plate, and further drives the top block of the L-shaped connecting rod to abut against the side face of the sealing plate, so that the sealing plate extrudes and compresses the third spring, and finally the storage box and the sealing cover are sealed;
through intermittent type to the bin is opened or is closed, realizes the purpose of the intermittent exhaust of nitrogen gas, reduces nitrogen gas too much from this, and refrigeration is colder the condition that excessively cools off appears in the raw materials cooling process in to the agitator. Namely, the coagulation phenomenon of the blackcurrant seed oil, the pumpkin seed oil and the cod liver oil in the stirring process of the mixture of the blackcurrant seed oil, the pumpkin seed oil and the cod liver oil is reduced; meanwhile, the situation that the vitamins are subjected to nutrient loss due to high temperature in the stirring process of the vitamin C, the vitamin E and the vitamin B6 can be reduced through cooling; namely, the condition that the vitamins lose efficacy due to high temperature generated in the squeezing process or high temperature generated in the stirring process is reduced, and the effectiveness of the medicinal components of the medicament in the preparation process is effectively guaranteed.
It will be apparent to those skilled in the art that various changes and modifications may be made in the present invention without departing from the spirit and scope of the invention. Thus, if such modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include such modifications and variations.
Claims (8)
1. The preparation method of the medicine for treating female alopecia is characterized by comprising the following steps:
preparing black currant seed oil;
preparing pumpkin seed oil;
pouring the obtained blackcurrant seed oil and pumpkin seed oil into a stirring barrel;
injecting cod liver oil into a stirring barrel, and stirring to obtain a mixture of black currant seed oil, pumpkin seed oil and cod liver oil;
adding vitamin C, vitamin E and vitamin B6 into a stirring barrel, and stirring for 30-65 minutes;
adding cystine into a stirring barrel, and stirring for ten minutes; the medicine for treating alopecia is obtained.
2. The method of claim 1, wherein the step of injecting cod liver oil into the blender and blending the oil to obtain the mixture of blackcurrant seed oil, pumpkin seed oil and cod liver oil further comprises the steps of:
and opening the stirring barrel refrigeration mechanism, and refrigerating the mixture in the stirring barrel by using the stirring barrel refrigeration mechanism.
3. The process for preparing a medicament for treating alopecia in women according to claim 1, wherein the step of preparing blackcurrant seed oil further comprises the steps of:
taking mature blackcurrant fruits, removing blackcurrant pulp, and reserving blackcurrant seeds;
screening out the blackcurrant seeds with uniform size and full particles by using a material selecting machine, and cleaning the blackcurrant seeds by using a cleaning mechanism;
crushing the cleaned blackcurrant seeds by using a crusher;
pouring the crushed blackcurrant seeds into a squeezing barrel, starting a squeezing mechanism, and squeezing the blackcurrant seeds to obtain blackcurrant seed oil.
4. The method of claim 1, wherein the step of preparing the pumpkin seed oil comprises the steps of:
selecting full pumpkin seeds;
peeling with a decorticator to obtain pumpkin kernels;
crushing the pumpkin kernels by using a crusher;
and pouring the crushed pumpkin kernels into a squeezing barrel, starting a squeezing mechanism, and squeezing the pumpkin kernels to obtain the pumpkin seed oil.
5. The preparation method of the medicine for treating female alopecia is applicable to any one of claims 1 to 4, and is characterized in that the medicine for treating female alopecia is prepared according to the following medicine components:
black currant seed oil: 300 and 630 mg;
cod liver oil: 410 and 580 mg;
pumpkin seed oil: 320-550 mg;
lycopene: 0.6-2.3 mg;
vitamin C: 22-38 mg;
vitamin E: 12-26 mg;
vitamin B6: 0.2-0.8 mg;
cystine: 20-48 mg.
6. The medicament for treating female alopecia as claimed in claim 5, wherein the medicament for treating female alopecia is prepared from the following medicinal components:
black currant seed oil: 400 mg;
cod liver oil: 428 mg;
pumpkin seed oil: 436 mg;
lycopene: 0.9 mg;
vitamin C: 26 mg of the total weight of the composition;
vitamin E: 15 mg;
vitamin B6: 0.3 mg;
cystine: 23 mg.
7. The medicament for treating female alopecia as claimed in claim 5, wherein the medicament for treating female alopecia is prepared from the following medicinal components:
black currant seed oil: 450 mg;
cod liver oil: 450 mg;
pumpkin seed oil: 400 mg;
lycopene: 1 mg;
vitamin C: 30 mg;
vitamin E: 15 mg;
vitamin B6: 0.6 mg;
cystine: 42 mg.
8. The method of claim 1, wherein the step of preparing the composition for treating female alopecia comprises,
a stirring mechanism is erected above the stirring barrel, and a feeding hole and a discharging hole are arranged on the side wall of the stirring barrel at intervals;
a feed port of the stirring barrel is connected with the squeezing barrel;
the upper portion of squeezing the bucket erects presses the mechanism, the below of squeezing the bucket is equipped with the filter, the feed inlet of agitator passes through the pipe connection the below oil-out of squeezing the bucket.
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