CN112198652A - Inverted automatic slide scanner device and using method thereof - Google Patents
Inverted automatic slide scanner device and using method thereof Download PDFInfo
- Publication number
- CN112198652A CN112198652A CN202010942215.0A CN202010942215A CN112198652A CN 112198652 A CN112198652 A CN 112198652A CN 202010942215 A CN202010942215 A CN 202010942215A CN 112198652 A CN112198652 A CN 112198652A
- Authority
- CN
- China
- Prior art keywords
- ball screw
- axis
- slide
- lens
- axis ball
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
- G02B21/365—Control or image processing arrangements for digital or video microscopes
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/0036—Scanning details, e.g. scanning stages
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/0088—Inverse microscopes
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/24—Base structure
- G02B21/241—Devices for focusing
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/24—Base structure
- G02B21/248—Base structure objective (or ocular) turrets
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/24—Base structure
- G02B21/26—Stages; Adjusting means therefor
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
- G02B21/361—Optical details, e.g. image relay to the camera or image sensor
-
- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
- H04N1/00—Scanning, transmission or reproduction of documents or the like, e.g. facsimile transmission; Details thereof
- H04N1/00127—Connection or combination of a still picture apparatus with another apparatus, e.g. for storage, processing or transmission of still picture signals or of information associated with a still picture
Landscapes
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Engineering & Computer Science (AREA)
- Multimedia (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Signal Processing (AREA)
- Microscoopes, Condenser (AREA)
Abstract
The invention discloses an inverted automatic slide scanner device and a using method thereof, which are used for solving the problems that the prior cervical cytology slide reading personnel are deficient, the slide reading quantity pressure is high, the slide reading personnel have about 65 percent of sensitivity due to factors such as fatigue, skill level, subjective interpretation and the like, the slide reading efficiency is low, the inverted automatic slide scanner device comprises an inverted microscope, an electric objective table is additionally arranged on the inverted microscope, a positioning device is arranged on the objective table, the slide produced on the TCT slide producing machine does not need to be subjected to a complicated slide sealing process, the special slide making disc can be directly placed on the objective table to be scanned line by line, the system automatically finishes image focusing, scanning, image splicing and the like, the slide making device is simple, convenient, quick and rapid to use, the slide reading speed is greatly improved, and the slide sealing process in the traditional slide making method is complex in steps, low in efficiency, easy to oxidize and unsuitable for quick detection.
Description
Technical Field
The invention belongs to the field of liquid-based cytology reading; relates to cytology reading technology; in particular to an inverted automatic slide scanner device and a using method thereof.
Background
Cervical cancer is one of the two most common malignant tumors in gynecology, the incidence rate is second to breast cancer, but the mortality rate is the first to death of female cancer, and the 4 th mortality rate of all cancers. Every year, 50 million new patients die and 23 million die all over the world; accounts for 10% of female malignancies (2002). The average age is 52.2 years, and the distribution of the ages is two peaks 35-39 and 60-64. According to 2016 statistics of the international cancer research agency, 98900 cases of cervical cancer in China account for 18.7 percent of the total cases in the world;
at present, cervical cytology radiograph reading personnel are deficient, the radiograph reading quantity pressure is high, the sensitivity of radiograph reading personnel is only about 65 percent due to factors such as fatigue, skill level, subjective interpretation and the like, and the radiograph reading efficiency is low;
the automatic slide scanner can effectively assist a doctor in screening, obviously improve the slide reading efficiency, improve the sensitivity and specificity of pathological cells and realize the auxiliary slide reading of a cervical cell slide.
Disclosure of Invention
The invention aims to provide an inverted automatic slide scanner device and a using method thereof, which are used for solving the problems that the conventional cervical cytology film reading personnel are deficient, the pressure on the film reading quantity is high, the sensitivity of the film reading personnel is only about 65 percent due to factors such as fatigue, skill level and subjective interpretation, and the film reading efficiency is low.
The purpose of the invention can be realized by the following technical scheme:
an inverted automatic slide scanner device comprises a camera assembly, wherein the camera assembly is fixed on a support assembly through a bolt, the support assembly is composed of an upper support and a support base, the support base is fixed at one end of a support plate through a bolt, the support plate is fixed on a base assembly through a bolt, the base assembly is composed of a power supply groove, a switch, a Z-axis lifting motor, an access hole, a data transmission groove and a base main body, and the base main body is fixedly connected with an observation assembly through a bolt;
further, the upper end of the supporting plate is fixedly connected with an electric objective table assembly through a bolt, and the upper end of the electric objective table assembly is connected with a slice making disc assembly;
further, the electric objective table assembly comprises an objective bottom plate, an X-axis moving plate, a Y-axis moving plate, an X-axis ball screw and a Y-axis ball screw, the X-axis moving plate is fixed at the upper end of the objective bottom plate through bolts, the X-axis ball screw is mounted on one side of the X-axis moving plate, slide rails are symmetrically arranged on two sides of the upper end surface of the X-axis moving plate, the Y-axis moving plate is mounted at the upper end of the X-axis moving plate, slide blocks are arranged on two sides of the lower end of the Y-axis moving plate and are in sliding fit with each other, an X-axis ball screw nut seat is mounted on one side of the Y-axis moving plate and is in mutual fit with the X-axis ball screw, the Y-axis ball screw is mounted on one side of the Y-axis moving plate, a slide rail II is symmetrically arranged on the upper end surface of the Y, the slicing device comprises a slicing disc assembly, a slicing disc and a fixed handle, wherein the slicing disc assembly is composed of a slicing bin, the slicing bin is installed at the upper end of the slicing disc, a fixed hole is formed in the slicing disc, the bottom end of the fixed handle is embedded into the fixed hole of the slicing disc, two sides of the lower end of the slicing disc are respectively provided with a second sliding block, the second sliding blocks are in sliding fit with two sliding rails, one end of the slicing disc is provided with a Y-axis ball screw nut seat, the Y-axis ball screw is matched with the Y-axis ball screw nut seat, the slicing bin is clamped on the slicing disc through a buckle, the slicing disc is provided with a plurality of first holes, the slicing bin is provided with a plurality of second holes, and the first holes are arranged corresponding to the second holes;
furthermore, an inverted microscope is arranged at the bottom of the supporting plate and fixed at one end of the L-shaped support through a bolt, and the other end of the L-shaped support is fixed inside the base component through a bolt.
Further, the upper support is fixedly connected to the upper end of the support base through a bolt.
Furthermore, the camera component comprises an electronic camera, a focusing lens barrel and a focusing sheet, the focusing lens barrel is in clearance fit with the upper support of the support component, the focusing sheet is arranged inside the focusing lens barrel, and the electronic camera is fixed to the top of the focusing lens barrel through a buckle.
Further, one side of base main part is equipped with power supply groove and data transmission groove, one side that power supply groove and data transmission groove were kept away from to the base main part is equipped with the access hole, and the switch setting is in one side that power supply groove and data transmission groove are adjacent, and Z axle elevator motor installs in the one side of keeping away from the switch, and Z axle elevator motor meshes with lifting gear mutually.
Furthermore, the observation assembly comprises a lens barrel, a lens arm, a lens column, a lens base, an objective converter and an adjuster, wherein the lens base is fixed on the base main body through a bolt, the lens column is fixed on the lens base through a bolt, the lens arm is fixed on the lens column through a bolt, the lens barrel is placed in a cavity inside the lens arm, and the lens column is further provided with the objective converter and the adjuster.
An inverted automatic slide scanner device, the method of use comprising the steps of:
firstly, after starting, a slide making disc for completing slide making in a liquid-based cytology slide making machine is placed on an electric objective table assembly, then a start button is clicked, the electric objective table assembly drives an X-axis ball screw nut seat to move linearly in the X-axis direction through an X-axis ball screw, so that the electric objective table assembly resets in the X-axis direction, the electric objective table assembly drives a Y-axis ball screw nut seat to move linearly in the Y-axis direction through a Y-axis ball screw, so that the electric objective table assembly resets in the Y-axis direction, and the electric objective table assembly after resetting drives the X-axis ball screw nut seat and the Y-axis ball screw nut seat to move linearly in the X-axis direction and the Y-axis direction through the X-axis ball screw and the Y-axis ball screw;
the second step is that: when a slide reader needs to directly observe, the electric objective table assembly drives the slide making bin to move to a lens of the inverted microscope, focusing is carried out by adjusting the objective lens converter and the adjuster, after focusing is finished, the X-axis ball screw nut seat and the Y-axis ball screw nut seat are driven to linearly move in the X-axis direction and the Y-axis direction through the X-axis ball screw and the Y-axis ball screw, and the slide making bin is observed one by one through the lens cone arranged on the lens arm;
the third step: when the scanner scans, the electric objective table component drives the film making bins to move to the camera component one by one, the Z-axis lifting motor drives the lifting gear to rotate, the height of the camera component is adjusted, focusing is started, and after the focusing is finished, the X-axis ball screw nut seat and the Y-axis ball screw nut seat are driven to move linearly in the X-axis direction and the Y-axis direction through the X-axis ball screw and the Y-axis ball screw, so that the line-by-line scanning of the film making bins is finished;
the fourth step: the camera component transmits the pictures to the scanner, the scanner splices each scanned picture to generate a complete scanned picture, and the scanning is completed at the moment.
Compared with the prior art, the invention has the beneficial effects that:
1. the device provided by the invention uses the TCT slide making machine to make slides which are not sealed to be scanned and analyzed, is simple and convenient to use, greatly increases the slide reading speed, and solves the problem of a traditional slide sealing process with complicated steps in manual slide reading;
2. the device of the invention adopts the screw motor and the linear guide rail to realize the axial movement of the object stage X, Y, and the movement is precise and stable;
3. by adopting an inverted microscope, the slide which is prepared in the TCT film making machine but is not sealed can be scanned, and the sealing piece which still has fixing liquid in the film making bin can also be scanned.
Drawings
In order to facilitate understanding for those skilled in the art, the present invention will be further described with reference to the accompanying drawings.
FIG. 1 is a schematic structural view of an inverted automatic slide scanner apparatus;
FIG. 2 is a schematic view of the mating of the motorized stage assembly and the pellet assembly;
figure 3 is a schematic plan view of an inverted automatic slide scanner device.
In the figure: 1. a camera assembly; 2. a bracket assembly; 3. a pellet assembly; 301. preparing a sheet disc; 302. a tablet making bin; 303. fixing a handle; 4. an electric stage assembly; 401. a loading base plate; 402. moving the plate along the X axis; 403. moving the plate along the Y axis; 404. an X-axis ball screw; 405. a Y-axis ball screw; 5. a support plate; 6. an inverted microscope; 7. a base assembly; 8. and an observation component.
Detailed Description
The technical solutions of the present invention will be described clearly and completely with reference to the following embodiments, and it should be understood that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
As shown in fig. 1-3, an inverted automatic slide scanner device includes a camera assembly 1, the camera assembly 1 is composed of an electronic camera, a focusing lens barrel, and a focusing mechanism;
the electronic camera is fixed on the top of the focusing lens barrel through a buckle, the camera component 1 is installed on the support component 2 through a bolt, the support component 2 is composed of an upper support and a support base, and the upper support is fixedly connected to the upper end of the support base through a bolt;
the bracket component 2 is fixed at one end of the supporting plate 5 through a bolt, the supporting plate 5 is fixed on the base component 7 through a bolt, the base component 7 is fixedly connected with an observation component 8 through a bolt, the observation component 8 consists of a lens cone, a lens arm, a lens column, a lens base, an objective converter and an adjuster, the lens base is fixed on the base main body through a bolt, the lens column is fixed on the lens base through a bolt, the lens arm is fixed on the lens column through a bolt, the lens cone is placed in a cavity inside the lens arm, and the lens column is also provided with the objective converter and the adjuster;
an electric objective table component 4 is fixed at the upper end of a supporting plate 5 through a bolt, a sheet making disc component 3 is connected at the upper end of the electric objective table component 4, an inverted microscope 6 is arranged at the bottom of the supporting plate 5, the inverted microscope 6 is fixed at one end of an L-shaped support through a bolt, the other end of the L-shaped support is fixed inside a base component 7 through a bolt, the base component 7 comprises a power supply groove, a switch, a Z-axis lifting motor, an access hole and a data transmission groove, and a base main body, wherein the power supply groove and the data transmission groove are arranged on one side of the base main body;
the electric objective table assembly 4 comprises an objective bottom plate 401, an X-axis moving plate 402, a Y-axis moving plate 403, an X-axis ball screw 404 and a Y-axis ball screw 405, the X-axis moving plate 402 is fixed at the upper end of the objective bottom plate 401 through bolts, the X-axis ball screw 404 is installed at one side of the X-axis moving plate 402, slide rails are arranged at two ends of the outer side of the upper end surface of the X-axis moving plate 402, the Y-axis moving plate 403 is installed at the upper end of the X-axis moving plate 402, slide blocks are arranged at two sides of the lower end of the Y-axis moving plate 403 and are in sliding fit with each other, an X-axis ball screw nut seat is installed at one side of the Y-axis moving plate 403, the X-axis ball screw nut seat is in fit with the X-axis ball screw 404, a Y-axis ball screw 405 is installed at one side of, the slicing mechanism is characterized in that a slicing disc assembly 3 is mounted at the upper end of the Y-axis moving plate 403, the slicing disc assembly 3 comprises a slicing bin 302, a slicing disc 301 and a fixed handle 303, the slicing bin 302 is mounted at the upper end of the slicing disc 301, a fixed hole is formed in the slicing disc 301, the bottom end of the fixed handle 303 is embedded into the fixed hole of the slicing disc 301, two sliding blocks are arranged on two sides of the lower end of the slicing disc 301 and are in sliding fit with sliding rails, a Y-axis ball screw nut seat is mounted at one end of the slicing disc 301, a Y-axis ball screw 405 is matched with the Y-axis ball screw nut seat, the slicing bin 302 is clamped on the slicing disc 301 through a buckle, a plurality of first holes are formed in the slicing disc 301, a plurality of second holes are formed in the slicing disc 302, and the first holes and the second holes are correspondingly arranged;
an inverted automatic slide scanner device, the method of use comprising the steps of:
firstly, after starting up, a slide making disc 301 which finishes slide making in a liquid-based cytology slide making machine is placed on an electric objective table assembly 4, then a start button is clicked, the electric objective table assembly 4 drives an X-axis ball screw nut seat to move linearly in the X-axis direction through an X-axis ball screw 404, so that the electric objective table assembly 4 resets in the X-axis direction, the electric objective table assembly 4 drives a Y-axis ball screw nut seat to move linearly in the Y-axis direction through a Y-axis ball screw 405, so that the electric objective table assembly 4 resets in the Y-axis direction, and the electric objective table assembly 4 after resetting drives the X-axis ball screw nut seat and the Y-axis ball screw nut seat to move linearly in the X-axis direction and the Y-axis direction through the X-axis ball screw 404 and the Y-axis ball screw 405;
the second step is that: when a reader needs to directly observe, the electric objective table assembly 4 drives the film making bin 302 to move to a lens of the inverted microscope 6, the focusing is carried out by adjusting the objective lens converter and the adjuster, after the focusing is finished, the X-axis ball screw nut seat and the Y-axis ball screw nut seat are driven to linearly move in the X-axis direction and the Y-axis direction through the X-axis ball screw 404 and the Y-axis ball screw 405, and the film making bin 302 is observed one by one through a lens cone arranged on a lens arm;
the third step: when the scanner scans, the electric objective table component 4 drives the film making bin 302 to move to the camera component 1 one by one, the Z-axis lifting motor drives the lifting gear to rotate, the height of the camera component 1 is adjusted, focusing is started, after the focusing is finished, the X-axis ball screw nut seat and the Y-axis ball screw nut seat are driven to move linearly in the X-axis direction and the Y-axis direction through the X-axis ball screw 404 and the Y-axis ball screw 405, and the line-by-line scanning of the film making bin 302 is finished;
the fourth step: the camera assembly 1 transmits the pictures to the scanner, and the scanner splices each scanned picture to generate a complete scanned picture, and the scanning is completed at this time.
When the invention is used specifically: placing a flaking disc 301 which finishes flaking in a liquid-based cytology flaking machine on an electric objective table assembly 4, clicking a start button, driving an X-axis ball screw nut seat to linearly move in the X-axis direction by the electric objective table assembly 4 through an X-axis ball screw 404, so that the electric objective table assembly 4 resets in the X-axis direction, driving a Y-axis ball screw nut seat to linearly move in the Y-axis direction by the electric objective table assembly 4 through a Y-axis ball screw 405, and enabling the electric objective table assembly 4 to reset in the Y-axis direction; when a reader needs to directly observe, the electric objective table assembly 4 drives the film making bin 302 to move to a lens of the inverted microscope 6, the focusing is carried out by adjusting the objective lens converter and the adjuster, after the focusing is finished, the X-axis ball screw nut seat and the Y-axis ball screw nut seat are driven to linearly move in the X-axis direction and the Y-axis direction through the X-axis ball screw 404 and the Y-axis ball screw 405, and the film making bin 302 is observed one by one through a lens cone arranged on a lens arm;
when the scanner scans, the electric objective table component 4 drives the film making bin 302 to move to the camera component 1 one by one, the Z-axis lifting motor drives the lifting gear to rotate, the height of the camera component 1 is adjusted, focusing is started, after the focusing is finished, the X-axis ball screw nut seat and the Y-axis ball screw nut seat are driven to move linearly in the X-axis direction and the Y-axis direction through the X-axis ball screw 404 and the Y-axis ball screw 405, and the line-by-line scanning of the film making bin 302 is finished;
the objective table is driven by the control system to move by the screw motor, the screw motor drives the electric objective table assembly 4 to carry out X, Y-axis motion, so that the slide on the slide making bin 302 is scanned, and the Z-axis motion of the objective table is controlled by the lifting motor of the electric objective table assembly 4 additionally arranged on the inverted microscope 6, so that the focusing function is realized; in the circular area of the film making bin 302, when scanning point by point, the Z-axis control motor controls the lifting of the electric objective table component 4, so that the real-time focusing is realized if the focusing is not clear, and the optimal image is obtained; the shot pictures are transmitted to a computer through a data line of the camera for splicing processing. Because the inverted microscope 6 is adopted, the scanning of the slide which is not sealed and is manufactured in the TCT slide manufacturing machine can be realized, and the scanning can be carried out under the condition that the fixing liquid exists in the slide manufacturing bin 302; the adopted flaking disc 301 is provided with a hole with the same diameter as the flaking bin 302 under the flaking bin 302, so that the inverted microscope 6 can scan conveniently; the microscope is additionally provided with a motor for controlling the object stage to lift so as to control the Z-axis motion of the object stage and realize the focusing function. In the circular area of the film making bin 302, when scanning point by point, the Z-axis control motor controls the object stage to ascend and descend, so as to realize focusing and obtain the best image. The shot pictures are transmitted to a computer through a data line of the camera for splicing processing.
Open on the electronic objective table subassembly 4 and have the constant head tank, accomplish the film-making storehouse 302 after the film-making in the liquid-based cytology film-making machine, can directly take electronic objective table subassembly 4 on, can realize quick location and quick dress card.
The preferred embodiments of the invention disclosed above are intended to be illustrative only. The preferred embodiments are not intended to be exhaustive or to limit the invention to the precise forms disclosed. Obviously, many modifications and variations are possible in light of the above teaching. The embodiments were chosen and described in order to best explain the principles of the invention and the practical application, to thereby enable others skilled in the art to best utilize the invention. The invention is limited only by the claims and their full scope and equivalents.
Claims (6)
1. An inverted automatic slide scanner device comprises a camera component (1) and is characterized in that the camera component (1) is fixed on a support component (2) through bolts, the support component (2) is composed of an upper support and a support base, the support base is fixed at one end of a support plate (5) through bolts, the support plate (5) is fixed on a base component (7) through bolts, the base component (7) is composed of a power supply groove, a switch, a Z-axis lifting motor, an access hole, a data transmission groove and a base main body, and the base main body is fixedly connected with an observation component (8) through bolts;
the upper end of the supporting plate (5) is fixedly connected with an electric objective table assembly (4) through a bolt, and the upper end of the electric objective table assembly (4) is connected with a slice making disc assembly (3);
the electric objective table assembly (4) comprises an object carrying bottom plate (401), an X-axis moving plate (402), a Y-axis moving plate (403), an X-axis ball screw (404) and a Y-axis ball screw (405), wherein the X-axis moving plate (402) is fixed at the upper end of the object carrying bottom plate (401) through bolts, the X-axis ball screw (404) is installed on one side of the X-axis moving plate (402), slide rails are symmetrically arranged on two sides of the upper end surface of the X-axis moving plate (402), the Y-axis moving plate (403) is installed at the upper end of the X-axis moving plate (402), slide blocks are arranged on two sides of the lower end of the Y-axis moving plate (403), the slide blocks and the slide rails are in mutual sliding fit, an X-axis ball screw nut seat is installed on one side of the Y-axis moving plate (402), the X-axis ball screw nut seat and the X-axis ball screw (404) are in mutual, y axle movable plate (403) up end is close to edge bilateral symmetry and has seted up slide rail two, slice making dish subassembly (3) are installed to Y axle movable plate (403) upper end, slice making dish subassembly (3) comprise slice making storehouse (302), slice making dish (301) and fixed handle (303), slice making storehouse (302) are installed to slice making dish (301) upper end, slice making dish (301) inside sets up the fixed orifices, the bottom embedding of fixed handle (303) is in the fixed orifices of slice making dish (301), the lower extreme both sides of slice making dish (301) all are equipped with slider two, slider two and slide rail two sliding fit each other, Y axle ball screw nut seat is installed to the one end of slice making dish (301), Y axle ball screw (405) and Y axle ball screw nut seat mutually support and cooperate, slice making storehouse (302) are through the buckle chucking on slice making dish (301), the film making disc (301) is provided with a plurality of first holes, the film making bin (302) is provided with a plurality of second holes, and the plurality of first holes and the plurality of second holes are correspondingly arranged;
the bottom of backup pad (5) is equipped with inversion formula microscope (6), inversion formula microscope (6) pass through the bolt fastening in the one end of L type support, the other end of L type support passes through the inside of bolt fastening in base subassembly (7).
2. The inverted automatic slide scanner device according to claim 1, wherein the upper support is fixedly attached to the support base by bolts.
3. The inverted automatic slide scanner device according to claim 1, wherein the camera assembly (1) is composed of an electronic camera, a focusing lens barrel, a focusing sheet and a scanner, the focusing lens barrel is in clearance fit with the upper support of the support assembly (2), the focusing sheet is installed inside the focusing lens barrel, the electronic camera is fixed on the top of the focusing lens barrel through a buckle, and the electronic camera is connected with the scanner through a cable.
4. The inverted automatic slide scanner device according to claim 1, wherein the base body has a power supply slot and a data transmission slot on one side, the base body has an access hole on a side away from the power supply slot and the data transmission slot, the switch is disposed on a side of the power supply slot adjacent to the data transmission slot, the Z-axis lift motor is mounted on a side away from the switch, and the Z-axis lift motor is engaged with the lift gear.
5. The inverted automatic slide scanner device according to claim 1, wherein the observation assembly (8) is composed of a lens barrel, a lens arm, a lens column, a lens base, an objective lens changer and an adjuster, the lens base is fixed on the base body by bolts, the lens column is fixed on the lens base by bolts, the lens arm is fixed on the lens column by bolts, the lens barrel is placed in the cavity inside the lens arm, and the objective lens changer and the adjuster are further provided on the lens column.
6. A method of using an inverted automatic slide scanner, the method comprising the steps of:
firstly, after starting a machine, placing a slide making disc (301) which finishes slide making in a liquid-based cytology slide making machine on an electric objective table assembly (4), clicking a start button, wherein the electric objective table assembly (4) drives an X-axis ball screw nut seat to move linearly in the X-axis direction through an X-axis ball screw (404), so that the electric objective table assembly (4) resets in the X-axis direction, the electric objective table assembly (4) drives a Y-axis ball screw nut seat to move linearly in the Y-axis direction through a Y-axis ball screw (405), so that the electric objective table assembly (4) resets in the Y-axis direction, and the electric objective table assembly (4) after resetting drives the X-axis ball screw nut seat and the Y-axis ball screw nut seat to move linearly in the X-axis and Y-axis directions through the X-axis ball screw (404) and the Y-axis ball screw (405);
the second step is that: when a reader needs to directly observe, the electric objective table assembly (4) drives the film making bin (302) to move to a lens of the inverted microscope (6), focusing is carried out by adjusting the objective lens converter and the adjuster, after focusing is finished, the X-axis ball screw nut seat and the Y-axis ball screw nut seat are driven to linearly move in the X-axis direction and the Y-axis direction through the X-axis ball screw (404) and the Y-axis ball screw (405), and the film making bin (302) is observed one by one through the lens cones arranged on the lens arms;
the third step: when a scanner scans, the electric objective table component (4) drives the film making bin (302) to move onto the camera component (1) one by one, the Z-axis lifting motor drives the lifting gear to rotate, the height of the camera component (1) is adjusted, focusing is started, after the focusing is finished, the X-axis ball screw nut seat and the Y-axis ball screw nut seat are driven to move linearly in the X-axis direction and the Y-axis direction through the X-axis ball screw (404) and the Y-axis ball screw (405), and the line-by-line scanning of the film making bin (302) is finished;
the fourth step: the camera assembly (1) transmits the pictures to the scanner, the scanner splices each scanned picture to generate a complete scanned picture, and the scanning is finished at the moment.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010942215.0A CN112198652A (en) | 2020-09-09 | 2020-09-09 | Inverted automatic slide scanner device and using method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010942215.0A CN112198652A (en) | 2020-09-09 | 2020-09-09 | Inverted automatic slide scanner device and using method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112198652A true CN112198652A (en) | 2021-01-08 |
Family
ID=74014446
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010942215.0A Pending CN112198652A (en) | 2020-09-09 | 2020-09-09 | Inverted automatic slide scanner device and using method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN112198652A (en) |
Citations (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20010021064A1 (en) * | 1997-08-27 | 2001-09-13 | Shuji Toyoda | Inverted microscope |
| CN1529194A (en) * | 2003-10-14 | 2004-09-15 | 南开大学 | Microscope automatic operation system |
| CN1862308A (en) * | 2006-06-19 | 2006-11-15 | 中国科学院上海光学精密机械研究所 | Modularized scanning probe microscope |
| CN2867371Y (en) * | 2005-09-12 | 2007-02-07 | 桂林电子工业学院 | Automatic inverted microscope |
| CN2916659Y (en) * | 2006-06-19 | 2007-06-27 | 中国科学院上海光学精密机械研究所 | Modular scanning probe microscope |
| US20080055718A1 (en) * | 2006-09-06 | 2008-03-06 | Olympus Corporation | Microscope apparatus control method and microscope apparatus |
| CN102122063A (en) * | 2011-03-09 | 2011-07-13 | 北京工业大学 | Inverted digital holographic microscope |
| CN102351964A (en) * | 2011-07-15 | 2012-02-15 | 天津大学 | Controllable drop coalescence prepared anisotropic particle material and microfluid device |
| CN103353670A (en) * | 2013-08-01 | 2013-10-16 | 陈松 | Full-automatic electrically-controlled microscope sample bench |
| CN103698771A (en) * | 2013-12-17 | 2014-04-02 | 广西科技大学 | Experimental apparatus applying SRR in scanning imaging system |
| CN204188877U (en) * | 2014-08-15 | 2015-03-04 | 杭州卓腾信息技术有限公司 | Based on the panoramic scanning device of the micro-image of photoetching slide |
| CN104459972A (en) * | 2014-12-25 | 2015-03-25 | 中国科学院化学研究所 | Upright microscope and inverted microscope integrated photonic system |
| CN104830681A (en) * | 2014-02-09 | 2015-08-12 | 李保伟 | Cell culture glass slide system |
| CN205787338U (en) * | 2016-07-12 | 2016-12-07 | 江苏赛尔蒂扶医疗科技有限公司 | A kind of stage mechanism |
| CN206039027U (en) * | 2015-06-26 | 2017-03-22 | 莱卡微***Cms有限责任公司 | Microscope and microscopic system of camera with remotely controlled |
| CN107065160A (en) * | 2017-06-07 | 2017-08-18 | 李昕昱 | A kind of full-automatic micro- scanner |
| CN209656986U (en) * | 2019-03-14 | 2019-11-19 | 广州蓝勃生物科技有限公司 | A kind of cell microscopic imaging device |
| CN210894842U (en) * | 2019-12-10 | 2020-06-30 | 武汉六杰科技有限公司 | Simple microscopic imaging and automatic scanning acquisition device |
-
2020
- 2020-09-09 CN CN202010942215.0A patent/CN112198652A/en active Pending
Patent Citations (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20010021064A1 (en) * | 1997-08-27 | 2001-09-13 | Shuji Toyoda | Inverted microscope |
| CN1529194A (en) * | 2003-10-14 | 2004-09-15 | 南开大学 | Microscope automatic operation system |
| CN2867371Y (en) * | 2005-09-12 | 2007-02-07 | 桂林电子工业学院 | Automatic inverted microscope |
| CN1862308A (en) * | 2006-06-19 | 2006-11-15 | 中国科学院上海光学精密机械研究所 | Modularized scanning probe microscope |
| CN2916659Y (en) * | 2006-06-19 | 2007-06-27 | 中国科学院上海光学精密机械研究所 | Modular scanning probe microscope |
| US20080055718A1 (en) * | 2006-09-06 | 2008-03-06 | Olympus Corporation | Microscope apparatus control method and microscope apparatus |
| CN102122063A (en) * | 2011-03-09 | 2011-07-13 | 北京工业大学 | Inverted digital holographic microscope |
| CN102351964A (en) * | 2011-07-15 | 2012-02-15 | 天津大学 | Controllable drop coalescence prepared anisotropic particle material and microfluid device |
| CN103353670A (en) * | 2013-08-01 | 2013-10-16 | 陈松 | Full-automatic electrically-controlled microscope sample bench |
| CN103698771A (en) * | 2013-12-17 | 2014-04-02 | 广西科技大学 | Experimental apparatus applying SRR in scanning imaging system |
| CN104830681A (en) * | 2014-02-09 | 2015-08-12 | 李保伟 | Cell culture glass slide system |
| CN204188877U (en) * | 2014-08-15 | 2015-03-04 | 杭州卓腾信息技术有限公司 | Based on the panoramic scanning device of the micro-image of photoetching slide |
| CN104459972A (en) * | 2014-12-25 | 2015-03-25 | 中国科学院化学研究所 | Upright microscope and inverted microscope integrated photonic system |
| CN206039027U (en) * | 2015-06-26 | 2017-03-22 | 莱卡微***Cms有限责任公司 | Microscope and microscopic system of camera with remotely controlled |
| CN205787338U (en) * | 2016-07-12 | 2016-12-07 | 江苏赛尔蒂扶医疗科技有限公司 | A kind of stage mechanism |
| CN107065160A (en) * | 2017-06-07 | 2017-08-18 | 李昕昱 | A kind of full-automatic micro- scanner |
| CN209656986U (en) * | 2019-03-14 | 2019-11-19 | 广州蓝勃生物科技有限公司 | A kind of cell microscopic imaging device |
| CN210894842U (en) * | 2019-12-10 | 2020-06-30 | 武汉六杰科技有限公司 | Simple microscopic imaging and automatic scanning acquisition device |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| WO2018223510A1 (en) | Fully automatic microscopic scanner | |
| KR101636524B1 (en) | Apparatus for acquiring data of tongue and face images based on traditional chinese medicine | |
| CN201417255Y (en) | Digital core image scanner | |
| CN105988209B (en) | One kind being based on microscopical automatic detection system | |
| CN108254383A (en) | A kind of high-precision optical fiber adapter visual detection equipment | |
| CN111855578B (en) | Pathological section scanner | |
| CN216590694U (en) | Three-dimensional reconstruction shooting device based on multi-view vision | |
| CN113252691A (en) | Product defect detector and detection method | |
| CN109921082A (en) | Battery organizes disk machine automatically | |
| CN110456093A (en) | A kind of slide carousel, apparatus for automatically loading and pathological section scanner | |
| CN112198652A (en) | Inverted automatic slide scanner device and using method thereof | |
| CN109682809B (en) | All-in-one machine for imaging physical rock debris, physical rock core and physical specimen | |
| CN217717430U (en) | Focusing device of cell counter | |
| CN216669776U (en) | Strain gauge defect recognition equipment based on machine vision | |
| CN114577126B (en) | Non-contact double-layer composite quartz crucible wall thickness detection method | |
| CN109932367A (en) | A kind of curved surface carved image acquisition device | |
| CN216234801U (en) | Automatic get and put slide mechanism | |
| CN206818969U (en) | A kind of full-automatic micro- scanner | |
| CN114324161B (en) | Electronic chip vision detection device | |
| CN115188685A (en) | Solar cell defect detection device | |
| CN213541800U (en) | High-flexibility visual detection platform | |
| CN113640318A (en) | Four mirror surface intellectual detection system equipment of monocular | |
| CN207039795U (en) | A kind of full-automatic focusing machine of wide-angle camera one drag two double | |
| CN220854896U (en) | Clip full-automatic digital slice scanning system | |
| CN220829432U (en) | Vickers hardness tester capable of manually measuring and automatically measuring |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20210108 |