CN112156346A

CN112156346A - Vagina drug delivery device

Info

Publication number: CN112156346A
Application number: CN202011238527.XA
Authority: CN
Inventors: 江源; 戴毅敏
Original assignee: Nanjing Drum Tower Hospital
Current assignee: Nanjing Drum Tower Hospital
Priority date: 2020-11-09
Filing date: 2020-11-09
Publication date: 2021-01-01

Abstract

The invention discloses a vagina drug delivery device, wherein a drug delivery inner cavity is axially arranged in a drug delivery tube, the drug delivery inner cavity penetrates through the front end and the rear end of the drug delivery tube, a drug powder bin and a spraying bin are arranged in the drug delivery end, powdery vagina drug can be put in the drug powder bin, a drug leakage channel is arranged on the drug powder bin, the drug leakage channel is communicated with the drug delivery inner cavity, physiological saline is stored in the spraying bin, a spraying push plug is arranged in the spraying bin, the front end of a spraying push rod is inserted into the spraying bin from the rear end of the spraying bin, is fixedly connected with the spray push plug, the front part of the spray bin is provided with a physiological saline replenishing pipe which is communicated with an external physiological saline source, the connecting injection end is provided with a main push rod, a push handle and a main piston, the main piston is arranged in the administration inner cavity in a sliding way, the push handle is positioned at the rear end of the injection end and connected with the main push rod, and the rear end of the spraying push rod extends to the injection end. The invention can effectively reduce the administration difficulty of the fornix vaginalis and simultaneously improve the absorption degree of the medicine by the vaginal mucosa.

Description

Vagina drug delivery device

Technical Field

The invention relates to the technical field of medical equipment, in particular to a vaginal drug delivery device.

Background

The part surrounding the cervix uteri in medicine is called vaginal fornix, which is divided into an anterior part, a posterior part, a left part and a right part according to the position of the vaginal fornix, wherein the posterior fornix is deepest and is closely adjacent to the rectum in the sunken uterus and is the lowest part of the pelvic cavity. Vaginal administration is usually placed at this point clinically.

Clinical early pregnancy induced abortion and middle and late pregnancy induced abortion, misoprostol is placed in the fornix behind the vagina by fingers in a conventional administration operation, and the tablets promote cervical softening through mucosa absorption to achieve good abortion and induced abortion effects. Due to the longer posterior vaginal wall, typically 14-16 cm, the deep posterior fornix may not be reached by normal digital dosing. The drug tablet is not sufficiently absorbed when administered. Thereby causing the possibility of long induced labor time and even failure in abortion. Therefore, if the misoprostol can be ground into powder and sent to the vaginal vault through the device, the effect of abortion induction can be improved.

Currently, the vaginal use of misoprostol presents the following specific problems:

because the posterior vaginal wall is long and the posterior fornix is deep, the medicine can not be pushed to the top end of the posterior fornix of the vagina by the single finger for administration in the vagina, and the abortion and labor induction effects can be directly influenced.

Because the clinically used misoprostol is a tablet, the absorption degree of the clinical misoprostol after being placed into the vagina is poor, the residue of the previous medicine can still be seen when the medicine is placed again, and the medicine can not be fully absorbed to take effect, and if the misoprostol is crushed, the medicine can not be directly plugged by fingers.

When the medicine is put in, the patient adopts the lithotomy position, after the medicine is put in, the patient needs to lie in bed for one hour to wait for the medicine to be absorbed, and the medicine is likely to move downwards after standing and walking and can not stay in the deepest part of the fornix vaginae all the time, thereby influencing the medicine effect.

Disclosure of Invention

The present invention has been made to solve the problems mentioned in the background art, and an object of the present invention is to provide a vaginal drug delivery device, by which misoprostol pulverized into powder can be sprayed to the posterior fornix of the vagina and the absorbability of drug mucosa can be increased by spraying physiological saline, so that misoprostol can be completely absorbed by the vaginal mucosa, thereby achieving the effects of softening the cervix and improving the efficiency of abortion induction.

In order to achieve the technical purpose, the technical scheme adopted by the invention is as follows:

vagina device of dosing including dosing the pipe, doses the pipe including dosing the end and connecting the injection end, dose the end fixed front portion at connecting the injection end, wherein: the drug delivery tube is internally and axially provided with a drug delivery inner cavity, the drug delivery inner cavity penetrates through the front end and the rear end of the drug delivery tube, a powder bin and a spraying bin are arranged in the drug delivery end, powdery vagina drug can be put in the powder bin, a drug leaking channel is arranged on the powder bin and is communicated with the drug delivery inner cavity, a first one-way valve is arranged on the drug leaking channel, the first one-way valve allows the drug powder in the powder bin to enter the drug delivery inner cavity, otherwise, the drug powder is not allowed, physiological saline is stored in the spraying bin, a spraying push plug is arranged in the spraying bin, the front end of the spraying push rod is inserted into the spraying bin from the rear end of the spraying bin and is fixedly connected with the spraying push plug, the front part of the spraying bin is provided with a physiological saline replenishing tube which is communicated with an external physiological saline source, the front end of the drug delivery end is fixedly provided with, the medicine powder spray pipe is communicated with the front end of the medicine feeding cavity, the normal saline spray head is connected with the front end of the spray cabin, a second one-way valve is arranged on a connecting channel of the normal saline spray head and the spray cabin and allows liquid to enter the normal saline spray head from the spray cabin, otherwise, the normal saline is not allowed, when the normal saline is sprayed out from the normal saline spray head, the normal saline spray head faces the front of the medicine powder spray pipe, the connecting injection end is provided with a main push rod, a push handle and a main piston, the main piston is arranged in the medicine feeding cavity in a sliding manner, the push handle is positioned at the rear end of the connecting injection end and is connected with the main push rod, the rear end of the spray push rod extends to the connecting injection end and is fixedly connected with the main push rod through a connecting piece, the push handle pushes the main piston to slide in the medicine feeding cavity by pushing the main push rod, meanwhile, the main push rod drives the spray push rod to follow up, so that the spray push, the air supplementing channel is provided with a third one-way valve, the third one-way valve allows air outside the administration tube to enter the administration inner cavity, otherwise, the third one-way valve is not allowed, and the third one-way valve is positioned in front of the main piston.

In order to optimize the technical scheme, the specific measures adopted further comprise:

the front end and four corners of the sprinkler head are in arc transition.

The sprinkler head is fixedly provided with a soft pulling plate made of flexible materials, the front end of the soft pulling plate extends to the front of the administration tube and bends towards the outer side of the administration tube, and when the sprinkler head extends to the posterior fornix of vagina, the soft pulling plate can push away the cervix so as to fully expose the posterior fornix of vagina.

The administration cavity of the administration end is internally provided with a fourth one-way valve, the fourth one-way valve allows air flow to flow from back to front, otherwise, the fourth one-way valve is not allowed, and the fourth one-way valve is arranged at the front part of the medicine leakage channel.

The medicine powder bin is an openable bin, the cover body of the medicine powder bin is arranged on the outer surface of the medicine feeding pipe, and medicine powder can be supplemented into the medicine powder bin after the cover body of the medicine powder bin is opened.

The length of the administration tube is 20cm to 25 cm.

The invention provides a vagina drug delivery device, which is characterized in that a drug powder bin and a spray bin are arranged at the front part of a drug delivery tube, the drug powder bin is used for preventing powdered drug, the spray bin is used for storing normal saline, when the vagina drug delivery device is used, the drug powder in the drug powder bin can be sucked into a drug delivery inner cavity by pulling a push handle backwards, then the push handle is pushed, the drug powder is sprayed out from the front end of the drug delivery tube, the drug powder can be uniformly adhered to the rear fornix part of the vagina, meanwhile, the spray bin is linked with the push handle, when the push handle is pushed, the normal saline can be simultaneously input into a normal saline spray nozzle by the spray bin, the normal saline is sprayed out in a spray mode, the drug powder sprayed out from the front end of the drug delivery tube is wetted, and the absorption degree.

The vaginal suppository has a simple structure, can effectively reduce the administration difficulty of the posterior fornix vaginae, and simultaneously improves the absorption degree of the medicament by vaginal mucosa.

Drawings

FIG. 1 is an external structural view of the present invention;

FIG. 2 is a schematic view of the internal structure of the present invention;

FIG. 3 is an enlarged view of the portion A of FIG. 2;

FIG. 4 is an enlarged view of the portion B of FIG. 2;

FIG. 5 is an enlarged view of the structure of the portion C of FIG. 2;

FIG. 6 is an enlarged view of the structure of the portion D in FIG. 2;

fig. 7 is an enlarged view of the structure of the portion E of fig. 2.

The label names in the figure: the device comprises an administration tube 1, an administration end 11, a connecting injection end 12, an administration inner cavity 13, a main push rod 14, a push handle 15, a main piston 16, a third one-way valve 17, a fourth one-way valve 18, a connecting piece 19, a medicine powder bin 2, a first one-way valve 21, an atomizing bin 3, an atomizing push plug 31, an atomizing push rod 32, a normal saline supplementing tube 33, a second one-way valve 34, an atomizing head 4, a medicine powder spraying tube 41, a normal saline nozzle 42 and a soft pulling plate 5.

Detailed Description

Embodiments of the present invention are described in further detail below with reference to the accompanying drawings.

Vagina dosing device, including administering tube 1, administer tube 1 including dosing end 11 and connect injection end 12, dosing end 11 is fixed in connecting injection end 12 anterior, wherein: an administration inner cavity 13 is axially arranged in the administration tube 1, the administration inner cavity 13 penetrates through the front end and the rear end of the administration tube 1, a medicine powder bin 2 and a spraying bin 3 are arranged in the administration end 11, powdery vagina administration medicine can be placed in the medicine powder bin 2, a medicine leakage channel is arranged on the medicine powder bin 2 and is communicated with the administration inner cavity 13, a first one-way valve 21 is arranged on the medicine leakage channel, medicine powder in the medicine powder bin 2 is allowed to enter the administration inner cavity 13 by the first one-way valve 21, otherwise, physiological saline is stored in the spraying bin 3, a spraying push plug 31 is arranged in the spraying bin 3, the front end of a spraying push rod 32 is inserted into the spraying bin 3 from the rear end of the spraying bin 3 and is fixedly connected with the spraying push plug 31, a physiological saline replenishing tube 33 is arranged at the front part of the spraying bin 3, the physiological saline replenishing tube 33 is communicated with an external physiological saline source, a spraying head 4 is fixedly arranged at the front end of the administration end, a normal saline nozzle 42 is arranged at one side of the spraying head 4, the medicine powder spray pipe 41 is communicated with the front end of the medicine feeding inner cavity 13, the normal saline nozzle 42 is connected with the front end of the spraying bin 3, a second one-way valve 34 is arranged on a connecting channel between the normal saline nozzle 42 and the spraying bin 3, the second one-way valve 34 allows liquid to enter the normal saline nozzle 42 from the spraying bin 3, otherwise, the normal saline is not allowed, when the normal saline is sprayed out from the normal saline nozzle 42, the normal saline nozzle 42 is in a water mist shape, the normal saline nozzle 42 is just opposite to the front of the medicine powder spray pipe 41, the connecting injection end 12 is provided with a main push rod 14, a push handle 15 and a main piston 16, the main piston 16 is arranged in the medicine feeding inner cavity 13 in a sliding manner, the push handle 15 is arranged at the rear end of the connecting injection end 12, the push handle 15 is connected with the main push rod 14, the rear end of the spraying push rod 32 extends to the connecting end 12 and, meanwhile, the main push rod 14 drives the spray push rod 32 to follow up, so that the spray push plug 31 and the main piston 16 move synchronously, the middle part of the administration tube 1 is provided with an air supplement channel communicated with the side wall of the administration tube 1 and the administration inner cavity 13, the air supplement channel is provided with a third one-way valve 17, the third one-way valve 17 allows air outside the administration tube 1 to enter the administration inner cavity 13, otherwise, the third one-way valve 17 is not allowed to be positioned in front of the main piston 16.

In the embodiment, the front end and four corners of the shower head 4 are rounded.

In the embodiment, a soft pulling plate 5 is fixedly arranged on the sprinkler head 4, the soft pulling plate 5 is made of flexible materials, the front end of the soft pulling plate 5 extends to the front of the administration tube 1 and bends towards the outer side of the administration tube 1, and when the sprinkler head 4 extends to the posterior fornix of the vagina, the soft pulling plate 5 can push away the cervix so as to fully expose the posterior fornix of the vagina.

In the embodiment, a fourth one-way valve 18 is arranged in the administration cavity 13 of the administration end 11, the fourth one-way valve 18 allows air flow from back to front, and otherwise, the fourth one-way valve 18 is not allowed, and the fourth one-way valve 18 is arranged in the front of the medicine leakage channel.

In the embodiment, the powder chamber 2 is an openable chamber, the cover body of the powder chamber 2 is arranged on the outer surface of the administration tube 1, and the powder can be supplemented into the powder chamber 2 after the cover body of the powder chamber 2 is opened.

In the examples, the length of the administration tube 1 is 20cm to 25 cm.

In the embodiment, the diameter of the administration end 11 is larger than that of the connection injection end 12, and the connection part of the administration end 11 and the connection injection end 12 is in smooth transition.

In the examples, the administration end 11 has a diameter of 1.5cm to 1.8 cm.

The vagina administration device of the invention has the structure shown in figures 1-7, and the use mode is as follows:

before administration, misoprostol is ground into powder, the powder is added into a medicine powder bin 2, a normal saline supplementing pipe 33 is connected with a normal saline bag, then whether the device can normally discharge and spray is tested, a push handle 15 is pulled back, a main piston 16 is pulled back, a first one-way valve 21 and a third one-way valve 17 are opened, a fourth one-way valve 18 is closed, air enters the front part of an administration inner cavity 13 from the third one-way valve 17, meanwhile, medicine powder in the medicine powder bin 2 is sucked into the front part of the administration inner cavity 13 through the first one-way valve 21, a spray push rod 32 is pulled back along with the push handle 15, a second one-way valve 34 is closed, the spray bin 3 extracts normal saline from the normal saline supplementing pipe 33, then the push handle 15 is pushed forward, the main piston 16 advances, the first one-way valve 21 and the third one-way valve 17 are closed, the fourth one-way valve 18 and the second one-way valve 34 are opened, air and the medicine powder in the administration, meanwhile, the spraying push rod 32 is pushed forward along with the push handle 15, and the external physiological saline source is provided with a one-way valve for preventing backflow, so that the physiological saline in the spraying bin 3 can be sprayed out only from the physiological saline spray nozzle 42, the sprayed physiological saline is in a water mist shape and faces the front end of the medicinal powder spray pipe 41, the medicinal powder and the physiological saline are mixed to a certain degree, the adhesion capacity of the medicinal powder is improved, and the medicinal powder can be adhered to vaginal mucosa more easily. If the device can discharge and spray the medicine normally, the patient adopts the lithotomy position when the medicine is discharged, the device is inserted into the vagina of the patient, the front end of the device is positioned at the rear fornix of the vagina, the soft poking plate 5 is propped against the cervix, and the cervix is pushed away, so that the rear fornix of the vagina is fully exposed. The powder is then sprayed at the posterior fornix of the vagina by repeatedly pulling back and pushing forward on the push handle 15, and after administration is complete, the device is removed from the patient's vagina.

The above is only a preferred embodiment of the present invention, and the protection scope of the present invention is not limited to the above-mentioned embodiments, and all technical solutions belonging to the idea of the present invention belong to the protection scope of the present invention. It should be noted that modifications and embellishments within the scope of the invention may be made by those skilled in the art without departing from the principle of the invention.

Claims

1. Vagina dosing device, including dosing tube (1), dosing tube (1) including dosing end (11) and connect injection end (12), dosing end (11) fix and connect injection end (12) anterior, characterized by: the utility model discloses a medicine feeding device, including medicine feeding pipe (1), medicine feeding pipe (1) in the axial be provided with one and dose inner chamber (13), medicine feeding inner chamber (13) run through medicine feeding pipe (1) both ends around, medicine feeding end (11) in be provided with medicine powder storehouse (2) and spray storehouse (3), medicine powder storehouse (2) in can put into powdered vagina and use medicine, medicine powder storehouse (2) on be provided with one and leak the medicine passageway, leak medicine passageway and medicine feeding inner chamber (13) intercommunication, leak and install first check valve (21) on the medicine passageway, first check valve (21) allow the powder in medicine powder storehouse (2) to get into medicine feeding inner chamber (13), otherwise then not allow, spray storehouse (3) in store have physiological saline, be equipped with a spraying plug (31) in spray storehouse (3), the front end of a spraying push rod (32) inserts spray storehouse (3) from spray storehouse (3) rear end, with spraying plug (31) fixed connection, the anterior part of spraying storehouse (3) is installed normal saline and is supplyed pipe (33), normal saline supply pipe (33) and external normal saline source intercommunication, the front end fixed mounting who doses end (11) spray head (4), spray head (4) middle part be provided with powder spray tube (41), spray head (4) one side is provided with normal saline shower nozzle (42), powder spray tube (41) and dose inner chamber (13) front end intercommunication, normal saline shower nozzle (42) be connected with spraying storehouse (3) front end, and be provided with second check valve (34) on the connecting channel of normal saline shower nozzle (42) and spraying storehouse (3), second check valve (34) allow liquid to get into normal saline shower nozzle (42) from spraying storehouse (3), otherwise then do not allow, normal saline spout from normal saline shower nozzle (42), the spraying device is in a water mist shape, the normal saline spray head (42) is directly opposite to the front of the medicine powder spray pipe (41), the connecting injection end (12) is provided with a main push rod (14), a push handle (15) and a main piston (16), the main piston (16) is arranged in the medicine feeding inner cavity (13) in a sliding mode, the push handle (15) is located at the rear end of the connecting injection end (12), the push handle (15) is connected with the main push rod (14), the rear end of the spraying push rod (32) extends to the position of the connecting injection end (12) and is fixedly connected with the main push rod (14) through a connecting piece (19), the push handle (15) enables the main piston (16) to slide in the medicine feeding inner cavity (13) by pushing the main push rod (14), meanwhile, the main push rod (14) drives the spraying push rod (32) to move along with the spraying push plug (31) and the main piston (16) synchronously, and the middle of the medicine feeding pipe (1) is provided with a gas supplementing channel communicated with the side wall of the medicine feeding pipe (1) and the, the air supplementing channel is provided with a third one-way valve (17), the third one-way valve (17) allows air outside the administration tube (1) to enter the administration inner cavity (13), otherwise, the third one-way valve (17) is not allowed, and the third one-way valve (17) is positioned in front of the main piston (16).

2. The vaginal drug delivery device as claimed in claim 1, wherein: the front end and four corners of the sprinkler head (4) are in arc transition.

3. The vaginal drug delivery device as claimed in claim 2, wherein: sprinkler (4) on fixed mounting have one to dial soft board (5), dial soft board (5) for flexible material preparation, dial soft board (5) front end and extend to dosing pipe (1) the place ahead to dosing pipe (1) outside is crooked, when sprinkler (4) extend fornix behind the vagina, dial soft board (5) and can push away the cervix uteri, make fornix behind the vagina fully expose.

4. The vaginal drug delivery device as claimed in claim 3, wherein: a fourth one-way valve (18) is arranged in the administration inner cavity (13) of the administration end (11), the fourth one-way valve (18) allows air flow to flow from back to front, otherwise, the fourth one-way valve (18) is not allowed, and the fourth one-way valve (18) is arranged at the front part of the medicine leakage channel.

5. The vaginal drug delivery device as claimed in claim 4, wherein: the powder storehouse (2) be the storehouse that can open and shut, the lid setting of powder storehouse (2) is at the surface of dosing pipe (1), the lid in powder storehouse (2) is opened the back, can mend powder to in powder storehouse (2).

6. The vaginal drug delivery device as claimed in claim 5, wherein: the length of the administration tube (1) is 20cm to 25 cm.

7. The vaginal drug delivery device as claimed in claim 6, wherein: the diameter of the administration end (11) is larger than that of the connection injection end (12), and the connection part of the administration end (11) and the connection injection end (12) is in smooth transition.

8. The vaginal drug delivery device as claimed in claim 7, wherein: the diameter of the administration end (11) is 1.5cm to 1.8 cm.