CN112093280B - Hematopoietic stem cell blood bag cryopreservation box - Google Patents
Hematopoietic stem cell blood bag cryopreservation box Download PDFInfo
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- CN112093280B CN112093280B CN202011187532.2A CN202011187532A CN112093280B CN 112093280 B CN112093280 B CN 112093280B CN 202011187532 A CN202011187532 A CN 202011187532A CN 112093280 B CN112093280 B CN 112093280B
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
- B65D81/18—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents providing specific environment for contents, e.g. temperature above or below ambient
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D11/00—Containers having bodies formed by interconnecting or uniting two or more rigid, or substantially rigid, components made wholly or mainly of plastics material
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- B65D11/12—Containers having bodies formed by interconnecting or uniting two or more rigid, or substantially rigid, components made wholly or mainly of plastics material of polygonal cross-section and all parts being permanently connected to each other of drawer-and-shell type
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D25/00—Details of other kinds or types of rigid or semi-rigid containers
- B65D25/38—Devices for discharging contents
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D55/00—Accessories for container closures not otherwise provided for
- B65D55/02—Locking devices; Means for discouraging or indicating unauthorised opening or removal of closure
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D7/00—Containers having bodies formed by interconnecting or uniting two or more rigid, or substantially rigid, components made wholly or mainly of metal
- B65D7/02—Containers having bodies formed by interconnecting or uniting two or more rigid, or substantially rigid, components made wholly or mainly of metal characterised by shape
- B65D7/06—Containers having bodies formed by interconnecting or uniting two or more rigid, or substantially rigid, components made wholly or mainly of metal characterised by shape of polygonal cross-section, e.g. tins, boxes
- B65D7/10—Containers having bodies formed by interconnecting or uniting two or more rigid, or substantially rigid, components made wholly or mainly of metal characterised by shape of polygonal cross-section, e.g. tins, boxes of drawer-and-shell type
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
- B65D81/02—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents specially adapted to protect contents from mechanical damage
- B65D81/05—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents specially adapted to protect contents from mechanical damage maintaining contents at spaced relation from package walls, or from other contents
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
- B65D81/18—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents providing specific environment for contents, e.g. temperature above or below ambient
- B65D81/20—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents providing specific environment for contents, e.g. temperature above or below ambient under vacuum or superatmospheric pressure, or in a special atmosphere, e.g. of inert gas
- B65D81/2069—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents providing specific environment for contents, e.g. temperature above or below ambient under vacuum or superatmospheric pressure, or in a special atmosphere, e.g. of inert gas in a special atmosphere
- B65D81/2076—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents providing specific environment for contents, e.g. temperature above or below ambient under vacuum or superatmospheric pressure, or in a special atmosphere, e.g. of inert gas in a special atmosphere in an at least partially rigid container
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D9/00—Containers having bodies formed by interconnecting or uniting two or more rigid, or substantially rigid, components made wholly or mainly of wood or substitutes therefor
- B65D9/06—Boxes or crates of polygonal cross-section
- B65D9/08—Boxes or crates of polygonal cross-section of drawer-and-shell type
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Abstract
The invention relates to the technical field of medical equipment, in particular to a hematopoietic stem cell blood bag cryopreservation box which comprises a cryopreservation outer frame bearing device, a fixed elastic connecting device, a blood bag storage platform device, a telescopic fixed lock component, a connecting and stretching device, a cooling storage drawer device, a ventilation plugging sliding plug device and an upper sealing plate component, wherein the fixed elastic connecting device is provided with six fixed elastic connecting devices, the six fixed elastic connecting devices are fixedly connected in the cryopreservation outer frame bearing device, the blood bag storage platform device is fixedly connected above the six fixed elastic connecting devices, the blood bag storage platform device is in sliding connection with the cryopreservation outer frame bearing device, the telescopic fixed lock component is in sliding connection with the blood bag storage platform device, and the telescopic fixed lock component is in contact with the blood bag storage platform device and is in sliding connection. The device can be used for freezing and storing hematopoietic stem cells in blood bags, and ensures the survivability of the hematopoietic stem cells in the transportation process.
Description
Technical Field
The invention relates to the technical field of medical equipment, in particular to a hematopoietic stem cell blood bag cryopreservation box.
Background
Hematopoietic stem cells refer to stem cells in bone marrow, have self-renewal ability and can differentiate into various blood cell precursors, eventually producing various blood cell components including erythrocytes, leukocytes and platelets, which can also differentiate into various other cells. The hematopoietic stem cells have good differentiation and proliferation capabilities, and can help many people with blood diseases, most commonly leukemia, the donated hematopoietic stem cells do not have great harm to the body of a donor, the hematopoietic stem cells need to be stored in a blood bag and transported when the hematopoietic stem cells are donated in different places, and the hematopoietic stem cells need to be frozen in the blood bag during transportation, so the design of the hematopoietic stem cell blood bag freezing storage box is particularly important.
Disclosure of Invention
The invention relates to the technical field of medical equipment, in particular to a hematopoietic stem cell blood bag cryopreservation box which comprises a cryopreservation outer frame bearing device, a fixed elastic connecting device, a blood bag storage platform device, a telescopic fixed locking member, a connecting and stretching device, a cooling storage drawer device, a ventilation plugging sliding plug device and an upper sealing plate member.
Hemopoietic stem cell blood bag cryopreserved box, store platform device, flexible fixed lock component, connection draw gear, cooling storage drawer device, shutoff sliding plug device of taking a breath and upper seal plate component, its characterized in that including cryopreserving frame bearing device, fixed elasticity connecting device, blood bag: six fixed elastic connecting devices are arranged and are fixedly connected in the freezing and storing outer frame bearing device, the blood bag storage platform device is fixedly connected above the six fixed elastic connecting devices and is connected with the freezing outer frame bearing device in a sliding way, the freezing outer frame bearing device is connected with a telescopic fixing locking component in a sliding way, the telescopic fixing locking component is contacted with the blood bag storage platform device and is connected with the blood bag storage platform device in a sliding way, the connecting and stretching device is fixedly connected with the rear end of the telescopic fixing and locking component, the freezing outer frame bearing device is connected with a cooling storage drawer device in a sliding way, the left end of the freezing and storing outer frame bearing device is connected with a ventilation plugging sliding plug device, and an upper sealing plate component is hinged above the freezing and storing outer frame bearing device.
As a further optimization of the technical scheme, the cryopreservation outer frame bearing device of the hematopoietic stem cell and blood bag cryopreservation box comprises a storage outer frame, a gas inlet pipe, an exhaust pipe and a drawer sliding opening, wherein the gas inlet pipe and the exhaust pipe are fixedly connected to the left end of the storage outer frame, the gas inlet pipe is positioned below the exhaust pipe, and the drawer sliding opening is arranged below the right end of the storage outer frame.
As a further optimization of the technical scheme, the fixed elastic connecting device of the hematopoietic stem cell blood bag cryopreservation box comprises a vertical bearing cavity, a limiting ring, six lifting slide columns, a limiting slide plate and lifting springs, wherein the limiting ring is fixedly connected above the vertical bearing cavity, the limiting slide plate is fixedly connected below the lifting slide columns, the lifting springs are placed in the vertical bearing cavity and are located below the limiting slide plate, the six fixed elastic connecting devices are provided, the six vertical bearing cavities are uniformly and fixedly connected below the inner part of the storage frame, and the six lifting springs are all located above the bottom surface of the storage frame.
As a further optimization of the technical scheme, the blood bag storage platform device of the hematopoietic stem cell blood bag cryopreservation box comprises a bearing transverse plate, communication holes, a storage isolation frame and right-angle locking blocks I, wherein the bearing transverse plate is provided with a plurality of communication holes, the storage isolation frame is fixedly connected above the bearing transverse plate, the right-angle locking blocks I are fixedly connected below the bearing transverse plate, the outer ends of the right-angle locking blocks I are designed to be inclined planes, sponges are adhered to right-angle edges of the right-angle locking blocks I, and the bearing transverse plate is fixedly connected above the six lifting sliding columns.
As a further optimization of the technical scheme, the telescopic fixing lock component of the hematopoietic stem cell and blood bag cryopreservation box comprises a right-angle lock block II, telescopic sliding columns and a switch spring, wherein the outer end of the right-angle lock block II is designed to be an inclined surface, a sponge is adhered to the right-angle edge of the right-angle lock block II, two telescopic sliding columns are fixedly connected to the rear of the right-angle lock block II, the switch spring is sleeved on each of the two telescopic sliding columns, the two telescopic sliding columns are both in sliding connection with the storage outer frame, the two switch springs are both located between the right-angle lock block II and the storage outer frame, and the right-angle lock block I is in contact with and in sliding connection with the right-angle lock block II.
As a further optimization of the technical scheme, the connecting and stretching device of the hematopoietic stem cell and blood bag cryopreservation box comprises a connecting pulling plate, bearing lug plates and a handle cylinder, wherein the connecting pulling plate is fixedly connected behind the two telescopic sliding columns, the connecting pulling plate is attached to the storage outer frame, the two bearing lug plates are fixedly connected behind the connecting pulling plate, and the handle cylinder is fixedly connected between the two bearing lug plates.
As a further optimization of the technical scheme, the cooling storage drawer device of the hematopoietic stem cell and blood bag cryopreservation box comprises an ice storage drawer, a fixed side plate and fixing bolts I, wherein the ice storage drawer is slidably connected in a drawer sliding port, the right end of the ice storage drawer is fixedly connected with the fixed side plate, the fixed side plate is attached to a storage outer frame, the four corners of the fixed side plate are rotatably connected with the fixing bolts I, and the four fixing bolts I are respectively connected with the storage outer frame through threads.
As a further optimization of the technical scheme, the ventilation sealing sliding plug device of the hematopoietic stem cell and blood bag cryopreservation box comprises two limiting vertical shafts, a bearing sliding plate, a sealing plug, two end fixing plates, an extrusion sliding column, a sealing spring and a handle circular plate, wherein the two limiting vertical shafts are fixedly connected with a storage outer frame, the bearing sliding plate is slidably connected with the two limiting vertical shafts, the sealing plug is fixedly connected onto the bearing sliding plate, the sealing plug is slidably connected into an exhaust pipe, the outer ends of the two limiting vertical shafts are fixedly connected with the end fixing plates, the end fixing plates are slidably connected with the extrusion sliding column, the extrusion sliding column is fixedly connected with the bearing sliding plate, the extrusion sliding column is sleeved with the sealing spring, the sealing spring is positioned between the sliding plate and the end fixing plates, and the outer end of the extrusion sliding column is fixedly connected with the handle circular plate.
As a further optimization of the technical scheme, the upper sealing plate component of the hematopoietic stem cell and blood bag cryopreservation box comprises an upper cover plate, a fixing insertion hole and a fixing bolt II, wherein the front end of the upper cover plate is hinged with the storage outer frame, the fixing insertion hole is arranged at the center of the upper cover plate, two fixing bolts II are rotatably connected to the rear of the upper cover plate, and both the two fixing bolts II are in threaded connection with the storage outer frame.
As a further optimization of the technical scheme, a sealing strip is adhered above the storage outer frame of the hematopoietic stem cell blood bag cryopreservation box, and the sealing strip is positioned between the storage outer frame and the upper cover plate.
The hematopoietic stem cell blood bag cryopreservation box has the beneficial effects that:
place some ice-cubes and install in the ice storage drawer, reduce the temperature of storing in the frame, let gaseous admission pipe be connected with nitrogen generator, place a plurality of hematopoietic stem cell blood bags on the bearing diaphragm and lie in and store the isolation frame, install the upper cover plate, at this moment, hematopoietic stem cell blood bag can be stored to the device in, transport, after the device reachs the hospital, take out two fixing bolt I, backward pulling right angle locking piece II lets it break away from with a plurality of right angle locking piece I, at this moment, utilize a plurality of lift springs to drive bearing diaphragm rebound, at this moment, store the isolation frame and can open the upper cover plate, quick take out the hematopoietic stem cell blood bag and store next culture apparatus after opening, ensure the survival rate of hematopoietic stem cell.
Drawings
The invention is described in further detail below with reference to the accompanying drawings and specific embodiments.
In the description of the present invention, it should be noted that the terms "central", "longitudinal", "lateral", "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", "outer" and "upright", etc., indicate orientations or positional relationships based on those shown in the drawings, merely for convenience of description and simplification of description, and do not indicate or imply that the referred device or element must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention.
In the description of the present invention, it should be noted that, unless explicitly fixed or limited otherwise, the terms "mounted," "connected" and "connected" are to be understood broadly, and for example, they may be fixed or detachable, or they may be directly or indirectly connected through an intermediate medium, or they may be connected inside two components. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.
In addition, in the description of the present invention, the meaning of "a plurality", or "a plurality" is two or more unless otherwise specified.
FIG. 1 is a schematic diagram of a freezing storage box for hematopoietic stem cells and blood bags according to the present invention;
FIG. 2 is a schematic cross-sectional view of a part of a cryopreservation box for hematopoietic stem cells and blood bags;
FIG. 3 is a schematic structural view of a freezing outer frame bearing device;
FIG. 4 is another schematic structural diagram of the freezing frame carrying device;
FIG. 5 is a schematic view of a fixed elastic connecting device;
FIG. 6 is a cross-sectional structural view of the elastic fastening device;
FIG. 7 is a schematic view of a blood bag storage platform device;
FIG. 8 is another schematic view of the blood bag storage platform device;
FIG. 9 is a schematic view of the structure of the retractable locking member;
FIG. 10 is a schematic view of the connecting and stretching device;
FIG. 11 is a schematic view of a cooling storage drawer arrangement;
FIG. 12 is a schematic view of a ventilation occluding sliding plug device;
FIG. 13 is a schematic view of the upper seal plate member construction.
In the figure: freezing and storing the outer frame bearing device 1; storing the outer frame 1-1; a gas inlet pipe 1-2; 1-3 of an exhaust pipe; 1-4 drawer sliding openings; a fixed elastic connecting device 2; supporting the vertical cavity 2-1; 2-2 of a limiting ring; 2-3 of a lifting sliding column; 2-4 of a limiting sliding plate; 2-5 of a lifting spring; a blood bag storage platform device 3; supporting a transverse plate 3-1; a communicating hole 3-2; 3-3 of a storage isolation frame; a right-angle locking block I3-4; a telescopic fixing lock member 4; a right-angle locking block II 4-1; 4-2 of a telescopic sliding column; 4-3 of a switch spring; connecting a stretching device 5; connecting a pulling plate 5-1; a bearing ear plate 5-2; 5-3 of a handle cylinder; a cooling storage drawer device 6; an ice storage drawer 6-1; fixing the side plate 6-2; fixing bolt I6-3; a ventilation plugging sliding plug device 7; a limiting vertical shaft 7-1; supporting the sliding plate 7-2; 7-3 of plugging; 7-4 of an end fixing plate; 7-5 of an extrusion sliding column; 7-6 of a plugging spring; 7-7 of a handle circular plate; an upper seal plate member 8; an upper cover plate 8-1; a fixed jack 8-2; and a bolt II8-3 is fixed.
Detailed Description
The first embodiment is as follows:
the embodiment is described below with reference to fig. 1-13, the invention relates to the technical field of medical equipment, and more specifically relates to a hematopoietic stem cell blood bag cryopreservation box, which comprises a cryopreservation outer frame bearing device 1, a fixed elastic connecting device 2, a blood bag storage platform device 3, a telescopic fixed locking member 4, a connecting and stretching device 5, a cooling storage drawer device 6, a ventilation blocking sliding plug device 7 and an upper sealing plate member 8, wherein a plurality of ice blocks are placed and installed in an ice storage drawer 6-1 to reduce the temperature in the storage outer frame 1-1, a gas inlet pipe 1-2 is connected with a nitrogen generator, a plurality of hematopoietic stem cell blood bags are placed on a bearing transverse plate 3-1 and positioned in a storage isolation frame 3-3, and the upper cover plate 8-1 is installed, so that the hematopoietic stem cell bags can be stored in the device for transportation, after the device arrives at a hospital, two fixing bolts I8-3 are taken out, the right-angle locking block II4-1 is pulled backwards to be separated from the right-angle locking blocks I3-4, the supporting transverse plate 3-1 is driven to move upwards by the aid of the lifting springs 2-5, the upper cover plate 8-1 is pushed open by the storage isolation frame 3-3, and after the upper cover plate is pushed open, hematopoietic stem cells and blood bags are rapidly taken out and stored in a next culture device, so that the survival rate of the hematopoietic stem cells is guaranteed;
hematopoietic stem cell blood bag cryopreserved box, including cryopreserved frame load-bearing device 1, fixed elasticity connecting device 2, blood bag storage platform device 3, flexible fixed lock component 4, connection draw gear 5, cooling storage drawer device 6, the shutoff sliding plug device 7 of taking a breath and upper seal plate component 8, its characterized in that: freezing frame load device 1 and nitrogen making machine and being connected, nitrogen can be beaten into to freezing frame load device 1 in to the nitrogen making machine, freezing frame load device 1 plays the effect of bearing the weight of and supporting, provides fixed space for whole device, fixed elasticity connecting device 2 be provided with six, six equal fixed connection of fixed elasticity connecting device 2 in freezing frame load device 1, utilize six fixed elasticity connecting device 2 to provide fixed space to blood bag storage platform device 3, every fixed elasticity connecting device 2 can stretch out and draw back, adjustable blood bag storage platform device 3's height, blood bag storage platform device 3 fixed connection in six fixed elasticity connecting device 2's top, can place the hemopoietic stem cell bag in blood bag storage platform device 3, blood bag storage platform device 3 and freezing frame load device 1 sliding connection, the cryopreservation outer frame bearing device 1 is connected with a telescopic fixed locking component 4 in a sliding way, the height of the blood bag storage platform device 3 is fixed by the telescopic fixed locking component 4, when the telescopic fixed locking component 4 is separated from the blood bag storage platform device 3, the blood bag storage platform device 3 can move upwards, the telescopic fixed locking component 4 is contacted with the blood bag storage platform device 3 and is connected with the blood bag storage platform device in a sliding way, the connecting and stretching device 5 is fixedly connected at the rear end of the telescopic fixed locking component 4, the telescopic fixed locking component 4 is driven by the connecting and stretching device 5 to move backwards, the cryopreservation outer frame bearing device 1 is connected with a cooling storage drawer device 6 in a sliding way, ice blocks are stored in the cooling storage drawer device 6, hematopoietic stem cells stored on the blood bag storage platform device 3 are cooled by the ice blocks, the left end of the cryopreservation outer frame bearing device 1 is connected with a plugging sliding plug device 7, when the temperature in the device is too high, the air in the device needs to be discharged through the movement of the ventilation sealing sliding plug device 7, nitrogen is injected into the device to ensure the proper temperature in the device, an upper sealing plate member 8 is hinged above the freezing and storing outer frame bearing device 1, and the upper sealing plate member 8 is used for shielding and sealing the upper part of the freezing and storing outer frame bearing device 1.
The second embodiment is as follows:
the embodiment is described below with reference to fig. 1 to 13, and the embodiment further describes a first embodiment, in which the freezing storage frame bearing device 1 includes a storage frame 1-1, a gas inlet pipe 1-2, an exhaust pipe 1-3, and a drawer sliding opening 1-4, the storage frame 1-1 plays a role of bearing, and provides a fixed space for the whole device, the left end of the storage frame 1-1 is fixedly connected with the gas inlet pipe 1-2 and the exhaust pipe 1-3, the gas inlet pipe 1-2 is connected with a nitrogen generator, nitrogen is pumped into the storage frame 1-1 through the gas inlet pipe 1-2 to ensure that the temperature in the storage frame 1-1 is proper, when the temperature in the storage frame 1-1 is too high, the air in the storage frame 1-1 is exhausted through the exhaust pipe 1-3, the gas inlet pipe 1-2 is positioned below the gas outlet pipe 1-3, a drawer sliding opening 1-4 is arranged below the right end of the storage outer frame 1-1, and the drawer sliding opening 1-4 can provide a sliding space for the ice storage drawer 6-1.
The third concrete implementation mode:
the embodiment is described below with reference to fig. 1-13, and the embodiment will be further described, where the fixed elastic connection device 2 includes a vertical bearing cavity 2-1, a limiting ring 2-2, a lifting slide post 2-3, a limiting slide plate 2-4, and a lifting spring 2-5, the vertical bearing cavity 2-1 plays a role of bearing connection, the limiting ring 2-2 is fixedly connected above the vertical bearing cavity 2-1, the limiting slide plate 2-4 can be limited by the limiting ring 2-2, the lifting slide post 2-3 is prevented from being separated from the limiting ring 2-2, the limiting slide plate 2-4 is fixedly connected below the lifting slide post 2-3, the lifting spring 2-5 is placed in the vertical bearing cavity 2-1, and the lifting spring 2-5 is located below the limiting slide plate 2-4, the fixed elastic force connecting device 2 is provided with six vertical bearing cavities 2-1 which are uniformly and fixedly connected below the inside of the storage outer frame 1-1, the six lifting springs 2-5 are all positioned above the bottom surface of the storage outer frame 1-1, and the desk calendars generated by the six lifting springs 2-5 are used for acting on the six limiting sliding plates 2-4, so that the six lifting sliding columns 2-3 can be driven to move upwards, and the six lifting sliding columns 2-3 can drive the transverse bearing plate 3-1 to move upwards.
The fourth concrete implementation mode:
the present embodiment is described below with reference to fig. 1-13, and the blood bag storage platform device 3 further described in the third embodiment of the present invention includes a supporting horizontal plate 3-1, a communication hole 3-2, a storage isolation frame 3-3, and a right-angled locking block I3-4, a plurality of hematopoietic stem cell blood bags can be placed on the supporting horizontal plate 3-1, the supporting horizontal plate 3-1 is provided with a plurality of communication holes 3-2, nitrogen and cold air flow through the plurality of communication holes 3-2 to the upper side of the supporting horizontal plate 3-1, to ensure the same gas temperature in the upper and lower sides of the supporting horizontal plate 3-1, the storage isolation frame 3-3 is fixedly connected above the supporting horizontal plate 3-1, the plurality of hematopoietic stem cell blood bags are separated by the storage isolation frame 3-3, the plurality of right-angled locking blocks I3-4 are fixedly connected below the supporting horizontal plate 3-1, utilize a plurality of right angle locking pieces I3-4 to fix the height of bearing diaphragm 3-1, the outer end of right angle locking piece I3-4 is the inclined plane design, and the inclined plane is convenient to slide and is extruded, and the right angle edge of right angle locking piece I3-4 is pasted and is had the sponge, and the purpose that is provided with the sponge plays the effect of buffering, and bearing diaphragm 3-1 fixed connection is in six lift travelers 2-3's top.
The fifth concrete implementation mode:
the fourth embodiment is described below with reference to fig. 1-13, and the fourth embodiment is further described in the present embodiment, in which the telescopic fixing lock member 4 includes a right angle lock block II4-1, a telescopic sliding column 4-2 and a switch spring 4-3, the outer end of the right angle lock block II4-1 is designed as an inclined surface, a sponge is adhered to the right angle edge of the right angle lock block II4-1, the right angle lock block II4-1 is used to limit a plurality of right angle lock blocks I3-4, when the right angle lock block II4-1 moves backward and is separated from the plurality of right angle lock blocks I3-4, the limit of the support transverse plate 3-1 is eliminated, at this time, the support transverse plate 3-1 will move upward instantly, when the support transverse plate 3-1 is pressed, the plurality of right angle lock blocks I3-4 will move downward, at this time, the inclined surfaces of the plurality of right angle lock blocks I3-4 will contact the inclined surfaces of the right angle lock blocks II4-1, at this time, the right-angle locking block II4-1 is driven to move backwards, when the two inclined planes are separated, the right-angle surfaces of the right-angle locking blocks I3-4 are in contact with the right-angle locking block II4-1, the right-angle locking blocks I3-4 are limited, the two telescopic sliding columns 4-2 are fixedly connected to the rear of the right-angle locking block II4-1, the two telescopic sliding columns 4-2 can provide a connecting space for the switch spring 4-3, the right-angle locking block II4-1 can be driven to move backwards by the two telescopic sliding columns 4-2, so that the right-angle locking block II4-1 is separated from the right-angle locking blocks I3-4, the switch springs 4-3 are sleeved on the two telescopic sliding columns 4-2, the right-angle locking block II4-1 is driven to move forwards by the elastic force generated by the two switch springs 4-3, and the right-angle locking blocks I3-4 are ensured to be limited successfully, two telescopic sliding columns 4-2 are connected with a storage outer frame 1-1 in a sliding mode, two switch springs 4-3 are located between a right-angle lock block II4-1 and the storage outer frame 1-1, and a right-angle lock block I3-4 is in contact with and connected with a right-angle lock block II4-1 in a sliding mode.
The sixth specific implementation mode:
the present embodiment is described below with reference to fig. 1 to 13, and the fifth embodiment is further described in the present embodiment, where the connection stretching device 5 includes a connection pulling plate 5-1, a bearing ear plate 5-2 and a handle cylinder 5-3, the connection pulling plate 5-1 is fixedly connected behind two telescopic sliding columns 4-2, the connection pulling plate 5-1 plays a role of bearing connection, the connection pulling plate 5-1 is attached to the storage outer frame 1-1, two bearing ear plates 5-2 are fixedly connected behind the connection pulling plate 5-1, the two bearing ear plates 5-2 can provide a fixed space for the handle cylinder 5-3, the handle cylinder 5-3 is fixedly connected between the two bearing ear plates 5-2, the handle cylinder 5-3 drives the right-angle locking block II4-1 to move backwards through the connection pulling plate 5-1 and the bearing ear plates 5-2, at this time, the supporting transverse plate 3-1 will move upward, and the hematopoietic stem cell blood bag on the supporting transverse plate 3-1 can be taken out.
The seventh embodiment:
the embodiment is described below with reference to fig. 1-13, and the sixth embodiment is further described in the present embodiment, in which the cooling storage drawer device 6 includes an ice storage drawer 6-1, a fixed side plate 6-2 and a fixing bolt I6-3, the ice storage drawer 6-1 is slidably connected in a drawer sliding opening 1-4, some ice cubes are stored in the ice storage drawer 6-1, the gas in the storage outer frame 1-1 is cooled, the right end of the ice storage drawer 6-1 is fixedly connected with the fixed side plate 6-2, the fixed side plate 6-2 plays a role of bearing connection, a gap between the fixed side plate 6-2 and the drawer sliding opening 1-4 is sealed, so as to prevent the temperature rise caused by air leakage of the device, and prevent hematopoietic stem cells from living, the fixed side plate 6-2 is attached to the storage outer frame 1-1, the four corners of the fixed side plate 6-2 are rotatably connected with fixed bolts I6-3, the four fixed bolts I6-3 are connected with the storage outer frame 1-1 through threads, and the fixed side plate 6-2 is fixedly connected with the storage outer frame 1-1 through the four fixed bolts I6-3.
The specific implementation mode is eight:
this embodiment mode will be described below with reference to fig. 1 to 13, and this embodiment mode will further describe embodiment mode seven: the ventilation blocking sliding plug device 7 comprises a limiting vertical shaft 7-1, a bearing sliding plate 7-2, a blocking plug 7-3, an end fixing plate 7-4, an extrusion sliding column 7-5, a blocking spring 7-6 and a handle circular plate 7-7, wherein the number of the limiting vertical shafts 7-1 is two, the two limiting vertical shafts 7-1 are both fixedly connected with a storage outer frame 1-1, the limiting vertical shaft 7-1 plays a role in bearing connection, the bearing sliding plate 7-2 is in sliding connection with the two limiting vertical shafts 7-1, the bearing sliding plate 7-2 can drive the blocking plug 7-3 to move, the blocking plug 7-3 is fixedly connected with the bearing sliding plate 7-2, the exhaust pipe 1-3 is blocked by the blocking plug 7-3, and the blocking plug 7-3 is in the exhaust pipe 1-3 in a sliding manner, the outer ends of the two limiting vertical shafts 7-1 are fixedly connected with end fixing plates 7-4, the end fixing plates 7-4 can provide a sliding space for the extrusion sliding columns 7-5, the end fixing plates 7-4 are connected with the extrusion sliding columns 7-5 in a sliding manner, the extrusion sliding columns 7-5 can provide a connecting space for the plugging springs 7-6, the extrusion sliding columns 7-5 are fixedly connected with the bearing sliding plates 7-2, the extrusion sliding columns 7-5 are sleeved with the plugging springs 7-6, the elastic force generated by the plugging springs 7-6 is utilized to act on the bearing sliding plates 7-2, the plugging springs 7-3 can be connected in the exhaust pipes 1-3 in a sliding manner to plug the exhaust pipes 1-3, the gas in the storage outer frame 1-1 cannot flow out, the plugging springs 7-6 are positioned between the bearing sliding plates 7-2 and the end fixing plates 7-4, the outer end of the extrusion sliding column 7-5 is fixedly connected with a handle circular plate 7-7, when the temperature in the storage outer frame 1-1 is overhigh, pulling the handle circular plate 7-7 to drive the sealing plug 7-3 to move leftwards through the bearing sliding plate 7-2 and the extrusion sliding column 7-5, at the moment, the exhaust pipe 1-3 is communicated with the air, a nitrogen making machine connected with the gas inlet pipe 1-2 is started, nitrogen is injected into the storage outer frame 1-1, hot gas in the storage outer frame 1-1 is extruded and exhausted by the nitrogen, after the temperature in the storage outer frame 1-1 is reduced, and (3) loosening the handle circular plate 7-7, and utilizing the elastic force generated by the plugging spring 7-6 to act on the bearing sliding plate 7-2 to enable the plugging plug 7-3 to be connected in the exhaust pipe 1-3 in a sliding manner to plug the exhaust pipe 1-3.
The specific implementation method nine:
the embodiment is described below with reference to fig. 1 to 13, and the embodiment further describes an embodiment eight, in which the upper sealing plate member 8 includes an upper cover plate 8-1, a fixing insertion hole 8-2 and a fixing bolt II8-3, the front end of the upper cover plate 8-1 is hinged to the storage outer frame 1-1 through a hinge, the upper cover plate 8-1 is used to seal the empty opening above the storage outer frame 1-1, the fixing insertion hole 8-2 is disposed at the center of the upper cover plate 8-1, a thermometer is fixedly connected to the fixing insertion hole 8-2, the temperature in the storage outer frame 1-1 is constantly observed, two fixing bolts II8-3 are rotatably connected to the rear of the upper cover plate 8-1, and the two fixing bolts II8-3 are both connected to the storage outer frame 1-1 through threads, two fixing bolts II8-3 are used to fixedly connect the upper cover plate 8-1 and the storage outer frame 1-1 together, so as to ensure the sealing between the upper cover plate 8-1 and the storage outer frame 1-1.
The specific implementation mode is ten:
the present embodiment is described below with reference to fig. 1 to 13, and the ninth embodiment is further described in the present embodiment that a sealing strip is attached on the upper side of the storage outer frame 1-1, the sealing strip is located between the storage outer frame 1-1 and the upper cover plate 8-1, and the sealing strip is arranged to seal the gap between the upper cover plate 8-1 and the storage outer frame 1-1, so as to ensure that no gap exists between the upper cover plate 8-1 and the storage outer frame 1-1.
The working principle of the hematopoietic stem cell blood bag cryopreservation box of the invention is as follows:
placing some ice blocks in an ice storage drawer 6-1 and connecting the ice blocks in a drawer sliding opening 1-4 in a sliding way, fixedly connecting a fixed side plate 6-2 with a storage outer frame 1-1 by four fixing bolts I6-3, plugging a gap between the ice storage drawer 6-1 and the drawer sliding opening 1-4 by the fixed side plate 6-2 at the moment to prevent the temperature from rising due to air leakage of the device, connecting an air inlet pipe 1-2 with a nitrogen generator, placing a plurality of hematopoietic stem cell blood bags on a supporting transverse plate 3-1 and in a storage isolation frame 3-3, fixedly connecting an upper cover plate 8-1 above the storage outer frame 1-1 by two fixing bolts II8-3 to realize the plugging of the storage outer frame 1-1 to the upper part, and then hermetically storing the hematopoietic stem cell blood bags in the device, carrying out transportation, constantly monitoring the temperature in the storage outer frame 1-1 in the transportation process, when the temperature in the storage outer frame 1-1 is overhigh, pulling the handle circular plate 7-7 to drive the sealing plug 7-3 to move leftwards through the supporting sliding plate 7-2 and the extrusion sliding column 7-5, then the exhaust pipe 1-3 is communicated with the air, starting a nitrogen generator connected with the air inlet pipe 1-2, injecting nitrogen into the storage outer frame 1-1, extruding and exhausting hot air in the storage outer frame 1-1 by using the nitrogen, loosening the handle circular plate 7-7 after the temperature in the storage outer frame 1-1 is reduced, applying the elastic force generated by the sealing spring 7-6 to the supporting sliding plate 7-2, and enabling the sealing plug 7-3 to be slidably connected in the exhaust pipe 1-3 to seal the exhaust pipe 1-3, and the sponge on the right-angle locking block II4-1 and the sponge on the right-angle locking block I3-4 can play the roles of buffering and damping, the vibration amplitude of hematopoietic stem cell blood bags is reduced, when the device arrives at a hospital, two fixing bolts I8-3 are taken out, the handle cylinder 5-3 is pulled to drive the right-angle locking block II4-1 to move backwards through the connecting pull plate 5-1 and the bearing ear plate 5-2, at the moment, the right-angle locking block II4-1 is separated from a plurality of right-angle locking blocks I3-4, at the moment, the bearing transverse plate 3-1 is driven to move upwards by a plurality of lifting springs 2-5, the upper cover plate 8-1 can be pushed open by the storage isolation frame 3-3 which moves upwards, the hematopoietic stem cell blood bags are rapidly taken out and stored in the next culture device after being pushed open, the survival rate of hematopoietic stem cells is ensured, when a hematopoietic stem cell blood bag is taken out, it is necessary to take out the hematopoietic stem cell blood bag quickly, and the hematopoietic stem cell blood bag cannot be brought into contact with air for a long time.
It is to be understood that the above description is not intended to limit the present invention, and the present invention is not limited to the above examples, and that various changes, modifications, additions and substitutions which are within the spirit and scope of the present invention and which may be made by those skilled in the art are also within the scope of the present invention.
Claims (2)
1. Hematopoietic stem cell blood bag cryopreserved box, including cryopreserved frame load-bearing device (1), fixed elasticity connecting device (2), blood bag storage platform device (3), flexible fixed lock component (4), connection stretching device (5), cooling storage drawer device (6), shutoff sliding plug device (7) and upper seal plate component (8) take a breath, its characterized in that: the fixed elastic connecting device (2) be provided with six, six equal fixed connection of fixed elastic connecting device (2) in freezing and depositing frame load-bearing device (1), blood bag store platform device (3) fixed connection in six fixed elastic connecting device's (2) top, blood bag store platform device (3) and freezing and depositing frame load-bearing device (1) sliding connection, freezing and depositing frame load-bearing device (1) go up sliding connection and have flexible fixed locking component (4), flexible fixed locking component (4) and blood bag store platform device (3) contact and sliding connection, connection stretching device (5) fixed connection in the rear end of flexible fixed locking component (4), freezing and depositing frame load-bearing device (1) go up sliding connection and have cooling drawer storage device (6), the left end of freezing and depositing frame load-bearing device (1) be connected with shutoff sliding plug device (7) of taking a breath, an upper sealing plate component (8) is hinged above the freezing outer frame bearing device (1);
the freezing and storing outer frame bearing device (1) comprises a storing outer frame (1-1), a gas inlet pipe (1-2), an exhaust pipe (1-3) and a drawer sliding opening (1-4), wherein the left end of the storing outer frame (1-1) is fixedly connected with the gas inlet pipe (1-2) and the exhaust pipe (1-3), the gas inlet pipe (1-2) is positioned below the exhaust pipe (1-3), and the drawer sliding opening (1-4) is arranged below the right end of the storing outer frame (1-1);
the fixed elastic connecting device (2) comprises a vertical bearing cavity (2-1), a limiting ring (2-2), a lifting sliding column (2-3), a limiting sliding plate (2-4) and a lifting spring (2-5), wherein the limiting ring (2-2) is fixedly connected above the vertical bearing cavity (2-1), the limiting sliding plate (2-4) is fixedly connected below the lifting sliding column (2-3), the lifting spring (2-5) is placed in the vertical bearing cavity (2-1), the lifting spring (2-5) is positioned below the limiting sliding plate (2-4), six fixed elastic connecting devices (2) are arranged, six vertical bearing cavities (2-1) are uniformly and fixedly connected to the lower part of the interior of the storage outer frame (1-1), and six lifting springs (2-5) are positioned above the bottom surface of the storage outer frame (1-1);
the blood bag storage platform device (3) comprises a bearing transverse plate (3-1), communication holes (3-2), a storage isolation frame (3-3) and right-angle locking blocks I (3-4), wherein the bearing transverse plate (3-1) is provided with a plurality of communication holes (3-2), the storage isolation frame (3-3) is fixedly connected above the bearing transverse plate (3-1), a plurality of right-angle locking blocks I (3-4) are fixedly connected below the bearing transverse plate (3-1), the outer ends of the right-angle locking blocks I (3-4) are designed to be inclined planes, sponges are adhered to right-angle edges of the right-angle locking blocks I (3-4), and the bearing transverse plate (3-1) is fixedly connected above the six lifting sliding columns (2-3);
the telescopic fixing lock component (4) comprises a right-angle lock block II (4-1), the device comprises a telescopic sliding column (4-2) and a switch spring (4-3), wherein the outer end of a right-angle lock block II (4-1) is designed to be an inclined plane, a sponge is adhered to the right-angle edge of the right-angle lock block II (4-1), two telescopic sliding columns (4-2) are fixedly connected to the rear side of the right-angle lock block II (4-1), the switch spring (4-3) is sleeved on each of the two telescopic sliding columns (4-2), the two telescopic sliding columns (4-2) are slidably connected with a storage outer frame (1-1), the two switch springs (4-3) are located between the right-angle lock block II (4-1) and the storage outer frame (1-1), and the right-angle lock block I (3-4) is in contact with and slidably connected with the right-angle lock block II (4-1);
the connecting and stretching device (5) comprises a connecting pulling plate (5-1), bearing lug plates (5-2) and a handle cylinder (5-3), the connecting pulling plate (5-1) is fixedly connected to the rear parts of the two telescopic sliding columns (4-2), the connecting pulling plate (5-1) is attached to the storage outer frame (1-1), the rear part of the connecting pulling plate (5-1) is fixedly connected with the two bearing lug plates (5-2), and the handle cylinder (5-3) is fixedly connected between the two bearing lug plates (5-2);
the cooling storage drawer device (6) comprises an ice storage drawer (6-1), a fixed side plate (6-2) and fixing bolts I (6-3), the ice storage drawer (6-1) is connected in a drawer sliding opening (1-4) in a sliding mode, the right end of the ice storage drawer (6-1) is fixedly connected with the fixed side plate (6-2), the fixed side plate (6-2) is attached to a storage outer frame (1-1), the four corners of the fixed side plate (6-2) are rotatably connected with the fixing bolts I (6-3), and the four fixing bolts I (6-3) are connected with the storage outer frame (1-1) through threads;
the ventilation sealing sliding plug device (7) comprises two limiting vertical shafts (7-1), two bearing sliding plates (7-2), two sealing plugs (7-3), two end fixing plates (7-4), an extrusion sliding column (7-5), a sealing spring (7-6) and a handle circular plate (7-7), wherein the two limiting vertical shafts (7-1) are fixedly connected with a storage outer frame (1-1), the bearing sliding plates (7-2) are slidably connected with the two limiting vertical shafts (7-1), the sealing plugs (7-3) are fixedly connected onto the bearing sliding plates (7-2), the sealing plugs (7-3) are slidably connected into exhaust pipes (1-3), the outer ends of the two limiting vertical shafts (7-1) are fixedly connected with the end fixing plates (7-4), an extrusion sliding column (7-5) is connected onto the end fixing plate (7-4) in a sliding manner, the extrusion sliding column (7-5) is fixedly connected with the bearing sliding plate (7-2), a plugging spring (7-6) is sleeved on the extrusion sliding column (7-5), the plugging spring (7-6) is positioned between the bearing sliding plate (7-2) and the end fixing plate (7-4), and a handle circular plate (7-7) is fixedly connected to the outer end of the extrusion sliding column (7-5);
the upper sealing plate component (8) comprises an upper cover plate (8-1), a fixing insertion hole (8-2) and a fixing bolt II (8-3), the front end of the upper cover plate (8-1) is hinged with the storage outer frame (1-1), the fixing insertion hole (8-2) is formed in the center of the upper cover plate (8-1), the rear of the upper cover plate (8-1) is rotatably connected with the two fixing bolts II (8-3), and the two fixing bolts II (8-3) are both in threaded connection with the storage outer frame (1-1).
2. The hematopoietic stem cell blood bag cryopreservation kit of claim 1 wherein: and a sealing strip is adhered above the storage outer frame (1-1), and is positioned between the storage outer frame (1-1) and the upper cover plate (8-1).
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| CN202011187532.2A CN112093280B (en) | 2020-10-30 | 2020-10-30 | Hematopoietic stem cell blood bag cryopreservation box |
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| KR101377467B1 (en) * | 2010-02-19 | 2014-03-25 | 도버 케미칼 코포레이션 | Alkylphenol free -liquid polymeric polyphosphite polymer stabilizers |
| US8573392B2 (en) * | 2010-09-22 | 2013-11-05 | Liposonix, Inc. | Modified atmosphere packaging for ultrasound transducer cartridge |
| CN108357763B (en) * | 2018-02-13 | 2019-07-16 | 京东方科技集团股份有限公司 | A kind of biological sheet storage device |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN208724772U (en) * | 2018-06-25 | 2019-04-12 | 上海帛龙生物科技有限公司 | A kind of candidate stem cell blood bag freezing storing box |
| CN211268328U (en) * | 2019-07-02 | 2020-08-18 | 中源协和生物细胞存储服务(天津)有限公司 | Stem cell cryopreservation box fixing structure |
| CN210793979U (en) * | 2019-10-23 | 2020-06-19 | 长春市会志印刷包装有限公司 | Multipurpose packing box |
| CN111776480A (en) * | 2020-08-20 | 2020-10-16 | 陕西生命源生物科技有限公司 | Insulation can of temporary storage stem cell preparation |
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