CN112075949A - Method, device and equipment for quickly searching event position of Anger detector - Google Patents

Method, device and equipment for quickly searching event position of Anger detector Download PDF

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Publication number
CN112075949A
CN112075949A CN202010930645.0A CN202010930645A CN112075949A CN 112075949 A CN112075949 A CN 112075949A CN 202010930645 A CN202010930645 A CN 202010930645A CN 112075949 A CN112075949 A CN 112075949A
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detector
event
anger
screening
energy
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王剑
程金星
王庆波
鲍天威
成建波
李佳健
林志业
黄帅
侯岩松
江年铭
刘迈
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Beijing Novel Medical Equipment Co ltd
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Beijing Novel Medical Equipment Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/42Arrangements for detecting radiation specially adapted for radiation diagnosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/02Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03Computed tomography [CT]
    • A61B6/037Emission tomography

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  • Radiology & Medical Imaging (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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Abstract

The invention discloses a method, a device and equipment for quickly searching an event position of an Anger detector, wherein an FPGA module is additionally arranged on the Anger detector, and the coordinate of gamma photons is quickly searched when the gamma photons are received by the detector, and the coordinate acquisition step comprises the following steps: the detector identifies energy signal events received by each photomultiplier tube, identifies energy characteristics Em and time characteristics Tm of each event, and sends Em and Tm to the FPGA module; and the FPGA module screens according to the input Tm and Em and outputs the coordinates and event information of the photomultiplier according to the screening result.

Description

Method, device and equipment for quickly searching event position of Anger detector
Technical Field
The invention relates to the field of nuclear medicine technical equipment, in particular to a method, a device and equipment for quickly searching an event position of an Anger detector.
Background
The Emission Tomography is a non-invasive nuclear medicine imaging method, and Single Photon Emission Computed Tomography (SPECT) is one kind of Emission Tomography, and is widely used in preclinical drug research and clinical disease diagnosis at present.
When an Anger detector of the SPECT device receives gamma photons, one gamma photon can excite a scintillation crystal to generate a plurality of photon signals, the photon signals are likely to be collected by different photomultiplier tubes, and in order to determine the position information of the gamma photon, after the detector collects event signals, later-stage processing equipment is required to remove noise of the signals sent by the photomultiplier tubes through operation software so as to obtain the final gamma photon position coordinates. At present, the mode of acquiring the gamma photon position through post-processing equipment needs more processing flows, and software compiling is complicated/the calculation process is complex.
Disclosure of Invention
In order to overcome the defects that the conventional mode of acquiring the gamma photon position by the nuclear medicine device through post-processing equipment has more processing flows and complicated software compiling/calculating process, the invention provides a method, a device and equipment for quickly searching the event position of an Anger detector.
The invention provides the following technical scheme:
a method for quickly searching an event position of an Anger detector is characterized in that an FPGA module is additionally arranged on the Anger detector, and when gamma photons are received by the detector, coordinates of the gamma photons are quickly searched out, wherein the coordinate acquisition step comprises the following steps:
the detector identifies energy signal events received by each photomultiplier tube, identifies energy characteristics Em and time characteristics Tm of each event, and sends Em and Tm to the FPGA module;
and the FPGA module screens according to the input Tm and Em and outputs the coordinates and event information of the photomultiplier according to the screening result.
Further, the time characteristic Tm is energy peak corresponding time information of each event, and the energy characteristic Em is energy peak energy information of each time.
Further, the screening steps of Tm and Em comprise: and screening the events with Tm in the same event window into a group, and screening the events with Em in the same energy threshold range into a group.
Further, the screening step further comprises a combination screening step, and the combination screening step comprises: screening events of which the lower threshold is less than or equal to Em and less than or equal to the upper threshold and the | T0-Tm | is less than or equal to an event window, and outputting the events meeting the conditions as screening results; where T0 is the timestamp value that the main peak triggers if the Em condition is met.
Further, the screening result includes time characteristic Tm, energy characteristic Em, and location information of each event.
The invention also provides a device adopting the method, and the device comprises an Anger detector and an FPGA module which is arranged together with the Anger detector.
Further, the device also comprises an identification module, wherein the identification module is arranged together with the Anger detector and used for identifying Tm and Em information for each event.
Furthermore, the device also comprises an output module, wherein the output module is respectively connected with the Anger detector and the FPGA module and used for outputting the screening result.
The invention also proposes a device for a nuclear medicine apparatus, in particular a SPECT or PET apparatus, which uses the apparatus described above.
According to the technical scheme, the hardware searching circuit is added on the Anger detector, the coordinate position of the gamma photon is directly output, the calculation efficiency of firmware grouping and Anger position is high, the real-time performance is good, the resource cost is low, the reaction speed and the applicability of the detector are improved, the processing flow is saved, and the complexity of later equipment software is reduced.
Drawings
Fig. 1 is a schematic method flow diagram of an embodiment of a method for rapidly finding an event position of an Anger detector according to the present invention;
fig. 2 is a schematic diagram of a screening process of an embodiment of the method for rapidly searching an event position of an Anger detector according to the invention;
fig. 3 is a schematic block structure diagram of an embodiment of the apparatus for rapidly finding an event position by using an Anger detector according to the present invention.
Detailed Description
The embodiments of the present invention will be described in further detail with reference to the drawings and examples. The following examples are intended to illustrate the invention but are not intended to limit the scope of the invention.
In the description of the present invention, "a plurality" means two or more unless otherwise specified; "notched" means, unless otherwise stated, a shape other than a flat cross-section. The terms "upper", "lower", "left", "right", "inner", "outer", "front", "rear", "head", "tail", and the like, indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, are only for convenience in describing and simplifying the description, and do not indicate or imply that the device or element referred to must have a particular orientation, be constructed in a particular orientation, and be operated, and thus, should not be construed as limiting the invention. Furthermore, the terms "first," "second," "third," and the like are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; may be directly connected or indirectly connected through an intermediate. The specific meaning of the above terms in the present invention can be understood as appropriate by those of ordinary skill in the art.
Referring to fig. 1, there is shown an event position fast-finding method for an Anger detector of the present invention, in which an FPGA module is added to the Anger detector, and when a gamma photon is received by the detector, the position of the gamma photon is found out quickly, and the coordinate acquiring step includes: referring to fig. 2, T in fig. 2 is time information, E is energy information, X, Y is position information of the PMT array, n is the total number of the photomultiplier arrays, and m is the number of the single photomultiplier tube. The detector identifies energy signal events received by each photomultiplier tube, identifies energy characteristics Em and time characteristics Tm of each event, and sends Em and Tm to the FPGA module; and the FPGA module screens according to the input Tm and Em and outputs the coordinates and event information of the photomultiplier according to the screening result. Referring to fig. 1 and 2, when a nuclear medicine device such as SPECT acquires a gamma photon signal, a plurality of gamma photons are incident on a scintillation crystal through a collimator, and the scintillation crystal generates a plurality of photons per gamma photon under the action of the gamma photons, and the photons generate photoelectric signal events after passing through a photomultiplier tube. When the current detector processes these events, it needs to determine which gamma photon generated the signal generated by each photon, and it needs to avoid the interference of the signal generated by the valid gamma photon by the photon signals generated by other gamma photons.
Therefore, the time identification Tm and the energy identification Em are carried out on the events of each photoelectric signal, the time characteristic Tm is the energy peak corresponding time information of each event, and the energy characteristic Em is the energy peak energy information of each time. And the later FPGA analyzes and judges the event according to the time information Tm and the energy mark Em of the event.
When an actual photomultiplier tube array (PMT array) is used, a gamma photon generates a plurality of photons on a scintillation crystal, and the photons are respectively received by adjacent photomultiplier tubes in the array, wherein the photomultiplier tube closest to the gamma photon striking position or most corresponding to the angle on the scintillation crystal receives the most photons, which is called a main tube, and the photomultiplier tubes around the main tube simultaneously generate signal reaction. In order to determine the position of the main pipe and avoid the interference of discrete single multiplier tube signals, when an event is judged, combined judgment is needed to judge whether the event meets the condition that signals exist in the main pipe and the light spot multiplier tubes around the main pipe. Referring to fig. 2, the screening steps for Tm and Em further include: and screening the events with Tm in the same event window into a group, and screening the events with Em in the same energy threshold range into a group. Further, the screening step further comprises a combination screening step comprising: screening events of which the lower threshold is less than or equal to Em and less than or equal to the upper threshold and the | T0-Tm | is less than or equal to an event window, and outputting the events meeting the conditions as screening results; where T0 is the timestamp value that the main peak triggers if the Em condition is met. In this embodiment, the position of the gamma photon event is determined by screening the time window and the energy window in which the same event is located, and simultaneously performing a combined screening of whether the simultaneous reaction of the main tube and the surrounding photomultiplier tubes is satisfied, and screening the position of the photomultiplier tubes satisfying the gamma photon energy peak characteristics within the time window.
The screening results include the time characteristic Tm, the energy characteristic Em, and the location information of each event.
The invention also provides a device adopting the method, which comprises an Anger detector and an FPGA module arranged together with the Anger detector, as shown in figure 3.
The device further comprises an identification module, wherein the identification module is arranged together with the Anger detector and is used for identifying Tm and Em information for each event.
The device also comprises an output module, wherein the output module is respectively connected with the Anger detector and the FPGA module and used for outputting the screening result.
The invention also proposes a device for a nuclear medicine apparatus, in particular a SPECT or PET apparatus, which uses the apparatus described above.
According to the technical scheme, the hardware FPGA searching circuit is added on the Anger detector, the coordinate position of the gamma photon is directly output, the applicability of the response speed of the detector is improved, the processing flow is saved, and the complexity of later equipment software is reduced.
The embodiments of the present invention have been presented for purposes of illustration and description, and are not intended to be exhaustive or limited to the invention in the form disclosed. Many modifications and variations will be apparent to those of ordinary skill in the art. The embodiment was chosen and described in order to best explain the principles of the invention and the practical application, and to enable others of ordinary skill in the art to understand the invention for various embodiments with various modifications as are suited to the particular use contemplated.

Claims (9)

1. A method for quickly searching an event position of an Anger detector is characterized in that an FPGA module is additionally arranged on the Anger detector, and when gamma photons are received by the detector, coordinates of the gamma photons are quickly searched out, wherein the coordinate acquisition step comprises the following steps:
the detector identifies energy signal events received by each photomultiplier tube, identifies energy characteristics Em and time characteristics Tm of each event, and sends Em and Tm to the FPGA module;
and the FPGA module screens according to the input time characteristic Tm and the input energy characteristic Em and outputs the coordinate and event information of the photomultiplier according to a screening result.
2. The event position fast search method for an Anger detector according to claim 1, wherein the time characteristic Tm is energy peak corresponding time information of each event, and the energy characteristic Em is energy peak energy information of each time.
3. The method for rapid event location finding for Anger detector according to claim 2, wherein the screening step of Tm and Em comprises:
and screening the events of the Tm in the same time window into a group, and screening the events of the Em in the same energy threshold range into a group.
4. The method for rapid event location finding for Anger detectors according to claim 3, wherein the screening step further comprises a combined screening step comprising: screening events of which the lower threshold is less than or equal to Em and less than or equal to the upper threshold and the | T0-Tm | is less than or equal to a time window, and outputting the events meeting the conditions as screening results; where T0 is the timestamp value that the main peak triggers if the Em condition is met.
5. The event location fast search method for Anger detector of claim 4, wherein the screening result comprises time characteristic Tm, energy characteristic Em and location information of each event.
6. An apparatus using the method according to any of claims 1-5, wherein the apparatus comprises an Anger detector and an FPGA module arranged together with the Anger detector.
7. The apparatus according to claim 6, further comprising an identification module provided with the Anger probe for identifying Tm and Em information for each event.
8. The device according to claim 7, further comprising an output module, wherein the output module is respectively connected with the Anger detector and the FPGA module, and is used for outputting the screening result.
9. An apparatus, characterized in that the apparatus employs the device of any of claims 6-8.
CN202010930645.0A 2020-09-07 2020-09-07 Method, device and equipment for quickly searching event position of Anger detector Pending CN112075949A (en)

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102283663A (en) * 2011-05-23 2011-12-21 江苏中惠医疗科技股份有限公司 Primitive event detection module for all-digital processing unit
CN103596504A (en) * 2011-06-16 2014-02-19 皇家飞利浦有限公司 Spatial sampling improvement for list-mode PET acquisition using planned table/gantry movement
CN103890611A (en) * 2011-10-06 2014-06-25 皇家飞利浦有限公司 Data-driven optimization of event acceptance/rejection logic
US20140353511A1 (en) * 2012-01-31 2014-12-04 Ut-Battelle, Llc Neutron camera employing row and column summations
CN104688261A (en) * 2015-03-19 2015-06-10 明峰医疗***股份有限公司 Full digitalization SiPM PET data collection system based on FPGA and ADC
CN104783829A (en) * 2015-04-29 2015-07-22 北京永新医疗设备有限公司 Processing method and system for single photon emission computed tomography
CN107595315A (en) * 2017-09-30 2018-01-19 华中科技大学 The acquisition methods of photoresponse line in a kind of transmitting imaging device

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102283663A (en) * 2011-05-23 2011-12-21 江苏中惠医疗科技股份有限公司 Primitive event detection module for all-digital processing unit
CN103596504A (en) * 2011-06-16 2014-02-19 皇家飞利浦有限公司 Spatial sampling improvement for list-mode PET acquisition using planned table/gantry movement
CN103890611A (en) * 2011-10-06 2014-06-25 皇家飞利浦有限公司 Data-driven optimization of event acceptance/rejection logic
US20140353511A1 (en) * 2012-01-31 2014-12-04 Ut-Battelle, Llc Neutron camera employing row and column summations
CN104688261A (en) * 2015-03-19 2015-06-10 明峰医疗***股份有限公司 Full digitalization SiPM PET data collection system based on FPGA and ADC
CN104783829A (en) * 2015-04-29 2015-07-22 北京永新医疗设备有限公司 Processing method and system for single photon emission computed tomography
CN107595315A (en) * 2017-09-30 2018-01-19 华中科技大学 The acquisition methods of photoresponse line in a kind of transmitting imaging device

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