CN112057350A - 一种透明质酸补水美白面膜 - Google Patents
一种透明质酸补水美白面膜 Download PDFInfo
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- CN112057350A CN112057350A CN202010815767.5A CN202010815767A CN112057350A CN 112057350 A CN112057350 A CN 112057350A CN 202010815767 A CN202010815767 A CN 202010815767A CN 112057350 A CN112057350 A CN 112057350A
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- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title claims abstract description 23
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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Abstract
本发明介绍了一种透明质酸补水美白面膜,由精华液和面膜膜布组成。精华液包含:四种特定分子量透明质酸钠组合,灵芝、树莓、黄瓜等植物提取物,玫瑰发酵液提取物,烟酰胺及相关辅助制剂。本发明能有效解决透明质酸面膜吸收率低,传统美白面膜效果欠佳的缺陷,能够深入持久保持肌肤水分,滋养淡化细纹,有效抑制黑色素的生成,焕白肌肤,令肌肤柔嫩水润。
Description
技术领域
本发明属于护肤品领域,具体涉及一种透明质酸补水美白面膜。
背景技术
当下女性护肤需求,主要集中在补水保湿调理和美白焕肤修复。目前已经出现了大量的面膜,但是这些面膜美白补水效果欠佳,因此需要一种能够深层持久补水,具有明显美白效果的面膜。
专利文献CN111346044A公开的技术方案中,将白术、白参等大量中草药碾磨成粉联合牛奶等混合成泥状后敷脸,制备成中药抗皱美白面膜。该发明中药成分复杂,由干粉直接混合制备,细腻和贴服性,相对欠佳,美白效果待考量。专利文献CN111346042A公开的技术方案中,将五味子、虎杖等植物成分研磨过筛提取功效成分制备增白面膜液,相对成分复杂,其中透明质酸仅作为少量添加剂,补水效果欠佳。专利文献CN104644510A公开的技术方案中,联合应用透明质酸和芦荟等提取物,侧重敏感皮肤修护,舒缓功效,不能满足美白滋润需求。
发明内容
基于背景技术存在的问题,本发明提出了一种透明质酸补水美白面膜,能够深层持久补水,具有明显美白效果。
为此,本发明采用以下技术方案:一种透明质酸补水美白面膜,由面膜精华液和面膜膜布构成;其特征在于面膜精华液含有以下重量份的原料组分:分子量120k-160kDa的透明质酸钠0.05-0.2份、60k-100kDa的透明质酸钠0.05-0.3份、10k-60kDa的透明质酸钠0.2-0.5份、3k-9kDa的水解透明质酸钠0.1-0.2份、灵芝提取物0.005-0.04份、黄瓜提取物0.05-0.2份、芦荟提取物0.02-0.2份、马齿苋提取物0.05-0.2份、树莓提取物0.01-0.04份、玫瑰发酵液提取物0.005-0.03份,,烟酰胺0.1-1份;稳定剂0.01-0.05份、芳香剂0.001-0.01份,防腐剂0.1-0.35份,增稠剂0.1-0.2份、保湿剂0.05-0.2份和纯水。
优选的,包括以下重量份的原料:分子量120k-160kDa的透明质酸钠0.1份、60k-100kDa的透明质酸钠0.2份、10k-60kDa的透明质酸钠0.4份、3k-9kDa的水解透明质酸钠0.1份、灵芝提取物0.01份、黄瓜提取物0.2份、芦荟提取物0.05份、马齿苋提取物0.1份、树莓提取物0.03份、玫瑰发酵液提取物0.01份,烟酰胺1份;稳定剂0.03份、芳香剂0.002份,防腐剂0.3份,增稠剂0.15份、保湿剂0.1份和纯水。烟酰胺1份;稳定剂0.03份、芳香剂0.002份,防腐剂0.3份,增稠剂0.15份、保湿剂0.1份和纯水。
所述稳定剂、芳香剂、防腐剂、增稠剂、保湿剂均可采用适于面膜使用的相应助剂,均可通过市场采购获得。烟酰胺作为美白成分,也可通过市场采购获得。优选地,所述稳定剂为甘草酸二钾,芳香剂为香精,防腐剂为Germall IS-45(美国ASHLAND公司的复配防腐剂),增稠剂为黄原胶,保湿剂为丁二醇。
所述黄瓜提取物,可通过市场采购获得,如广州美懿生物科技有限公司的小黄瓜提取液(成分≥10%);也可以在制备面膜精华液前,直接制备。其制备步骤为:将黄瓜切片捣碎,研磨过滤后用有机溶剂提取,蒸发浓缩后获得提取物,再用水溶解获得提取物溶液。黄瓜提取液富含维生素C、氨基酸,具备舒缓、保湿亮肤功效。
所述芦荟提取物,市场原料丰富,如广州美懿生物科技有限公司的库拉索芦荟提取液(成分≥10%);也可以在制备面膜精华液前,直接制备。其制备步骤为:将新鲜芦荟清洗,去皮切碎,匀浆过滤,用有机溶剂提取,蒸发浓缩后获得提取物,再用水溶解获得提取物溶液。芦荟提取液中包含氨基酸和复合多糖,可补充皮肤损失水分,保持肌肤柔润光滑有弹性。
所述马齿苋提取物,可购买获取,如广州美懿生物科技有限公司的马齿苋提取液(成分≥10%)。该提取液,属于化妆品护肤原料,作为抗刺激的生物活性添加剂。
所述灵芝提取物,可通过灵芝子实体切片干燥粉碎,溶剂提取,蒸发浓缩后获得提取物,再用水溶解获得提取物溶液;也可通过灵芝菌发酵液提取,蒸发浓缩后获得提取物,再用水溶解获得提取物溶液。灵芝提取物富含多糖、氨基酸等大量活性成分,可显著清除机体自由基,延缓细胞衰老。
所述树莓提取物,可将冻干树莓粉碎,有机溶剂提取,蒸发浓缩后获得提取物,再用水溶解获得提取物溶液;也可通过新鲜树莓研磨,过滤后有机溶剂提取,蒸发浓缩后获得提取物,再用水溶解获得提取物溶液。树莓作为世界第三代水果,富含黄酮、多酚等大量抗氧化活性物质,能够清除自由基,抑制酪氨酸酶,美白肌肤。
所述玫瑰发酵液提取物,可将玫瑰的冻干粉溶解灭菌后和微生物发酵培养,培养液灭菌过滤离心后取上清液,冷冻干燥,得到玫瑰发酵液提取物,用水溶解获得提取物溶液。有研究表明,玫瑰发酵液提取物具有较高的皮肤安全性,有抗氧化、抑制酪氨酸酶活性、抑制黑色素生成的功效。
优选地,所述面膜膜布为隐形蚕丝面膜,市场资源丰富,如南通康吉无纺布有限公司的羽翼丝光面膜。
本发明中,透明质酸补水美白面膜采用四种不同分子量透明质酸钠配方,有效解决吸收率低的问题,同时联合应用灵芝、树莓、玫瑰发酵液提取物、烟酰胺等成分,能深层补水滋润,淡化细纹,抑制黑色素沉淀,美白水润肌肤。
具体实施方式
以下结合实施例,对本发明做阐述,下述实施例是说明性的,不是限定性的,不能以下述说明限定本发明的保护范围。
先说明实施例1-3的透明质酸补水美白面膜的制备过程,实施例1-3的制备步骤相同,只是原料配方不同(见表1),所述制备过程包括以下步骤:
S1-1:将不同分子量透明质酸钠,根据表1混合配比投料,搅拌溶解得A相;
S1-2:将灵芝子实体,切片干燥粉碎,20目筛网过滤,乙醇超声水浴浸提24h后过滤,旋转蒸发(设定温度:55℃)浓缩,用纯化水溶解,过滤除菌,西林瓶加塞密封备用;
S1-3:将冻干的树莓粉碎,乙醇超声水浴浸提24h后,过滤旋转蒸发浓缩(设定温度:50℃),纯化水溶解,过滤除菌,西林瓶加塞密封备用;
S1-4:将玫瑰花冷冻干燥,粉碎过筛,纯化水溶解,湿热灭菌后与酵母菌液摇床35℃震荡培养30h,湿热灭菌,过滤离心,收集上清液,冷冻干燥后,纯化水溶解,过滤除菌,西林瓶加塞密封备用。
S1-5:通过有资质的供应商购买芦荟、黄瓜和马齿苋提取物以及烟酰胺、黄原胶等化妆品原料备用。(其中芦荟、黄瓜和马齿苋提取液以含量10%计算相应的提取物添加量。)
S1-6:将上述灵芝、树莓、黄瓜、芦荟、马齿苋和玫瑰发酵液提取物根据表1配方进行混合后得B相。
S1-7:将上述两相混合搅拌后,将保湿剂、防腐剂、稳定剂和芳香剂等按所述重量百分数一起置于配料罐中进行搅拌,根据配制量控制搅拌时间,保证制品溶解且制品搅拌均匀,得透明质酸补水美白面膜精华液;
S1-8:将步骤S1-7所得精华液,转移至灌装机中;
S1-9:将隐形蚕丝面膜折叠好,称取记录重量后,放入铝箔包装袋中;
S1-10:利用灌装机将精华液20g灌入包装袋中,热合,即得。
对比例1、2样品的制备步骤基本相同,原料配方不同(见表1),对比例1没有添加透明质酸钠成分;对比例2没有选取四种不同分子量的透明质酸钠组合配方。所述制备过程包括以下步骤:
S2-1:将透明质酸钠原料根据表1配方,搅拌溶解得A相;(对比例1无此步骤)
S2-2:将灵芝子实体,切片干燥粉碎,20目筛网过滤,乙醇超声水浴浸提24h后过滤,旋转蒸发(设定温度:55℃)浓缩,用纯化水溶解,过滤除菌,西林瓶加塞密封备用;
S2-3:将冻干的树莓粉碎,乙醇超声水浴浸提24h后,过滤旋转蒸发浓缩(设定温度:50℃),纯化水溶解,过滤除菌,西林瓶加塞密封备用;
S2-4:将玫瑰花冷冻干燥,粉碎过筛,纯化水溶解,湿热灭菌后与酵母菌液摇床35℃震荡培养30h,湿热灭菌,过滤离心,收集上清液,西林瓶加塞密封备用。
S2-5:通过有资质的供应商购买芦荟、黄瓜和马齿苋提取物以及烟酰胺、黄原胶等化妆品原料备用。(其中芦荟、黄瓜和马齿苋提取液以含量10%计算相应的提取物添加量。)
S2-6:将上述灵芝、树莓、黄瓜、芦荟、马齿苋和玫瑰发酵液提取物根据表1配方进行混合后得B相。
S2-7:将上述两相和保湿剂、防腐剂、稳定剂和芳香剂等按所述重量百分数一起置于配料罐中进行搅拌,根据配制量控制搅拌时间,保证制品溶解且制品搅拌均匀,得透明质酸补水美白面膜精华液;(对比例1无A相,即只有B相和配方要求重量分数的保湿剂、防腐剂、稳定剂和芳香剂等)
S2-8:将所得的精华液,转移至灌装机中;
S2-9:将隐形蚕丝面膜折叠好,称取记录重量后,放入铝箔包装袋中;
S2-10:利用灌装机将精华液20g灌入包装袋中,热合,即得。
表1:实施例1-3及对比例1、2的配方表:
实施例4-13的透明质酸补水美白精华液配方与上述实施例1-3以及对比例1、2的精华液配方相同,具体对应关系见表2;精华液的制备过程对应按照上述实施例1-3和对比例1、2的制备方法;后续使用的面膜膜布,存在差异(见表2),后续制备过程包括以下步骤:
S3-1:根据表2中实施例4-13的配方对应关系,以及表1中实施例1-3和对比例1-2的配方,对应按照上述实施例1-3和对比例1、2制备方法制备透明质酸补水美白精华液;
S3-2:根据表2,选用相应的面膜膜布(壳聚糖面膜或生物质纤维膜),以相同方式折叠好,称取记录重量后,放入铝箔包装袋中;
S3-3:利用灌装机将精华液20g灌入包装袋中,热合,即得。
表2:实施例1-13及对比例1、2样品的组成表:
实验例1
对上述实施例1-13例和对比例1-2例样品,进行面膜膜布对面膜精华液的吸附能力测试。设置三组平行数据。
实验方法:取上述实施例1-13和对比例1-2各三个样品,查询记录其面膜膜布重量M0。常温下,利用撕口撕开上述样品,将面膜膜布展开,悬空停留30s后,称取面膜膜布重量M1。计算不同面膜膜布对不同样品的吸附率F,吸附率%F=(M1-M0)/M0*100%。实验结果如表3。
表3:实施例1-13及对比例1、2的面膜膜布吸附率实验结果统计表
分析:实施例1-13例和对比例1-2例制品在不同的面膜膜布中,吸附率不同;相同面膜膜布对不同配方的吸附率也存在差异。发现隐形蚕丝面膜吸附率相对其余两款面膜膜布更高。本发明选用吸附率较高的隐形蚕丝面膜,其蚕丝般的触感和良好的服贴性,可明显提升补水滋润效果以及用户的体验。
实验例2
对实施例1-3例和对比例1、2例样品进行指标检测,检测结果见下述表4:
表4:实施例1-3及对比例1、2的样品指标检验结果统计表
分析:实施例1-3例和对比例1-2例样品,透明质酸补水美白面膜中多重透明质酸钠和美白功效成分的联合应用,以及防腐剂和助剂的用量和配比都满足行业标准中理化、感官以及微生物的要求。
实验例3
皮肤感受使用情况
实验方法:随机选择40例皮肤干燥,年龄25-35的女性,将其分成5组,每组8人,每周进行三次上述实施例1-3及对比例1、2的使用,每次贴敷15-20分钟,随后清洗面部,进行常规护肤步骤。连续使用2周、4周和8周后,利用肌肤水分测试仪记录皮肤使用2小时后的指标(保证环境:室温25±2℃,相对湿度50±5%);连续观察使用者的面部情况。使用8周后对面膜使用者进行调查问卷评分收集,评分标准:补水美白的效果不佳1分;补水美白的效果一般2分;补水持久,美白的效果可以,但不会考虑后期继续使用3分;补水效果持久良好,美白的效果明显,会考虑后期继续使用4分;补水滋养效果持久,美白的效果特别明显,皮肤明显改善5分。具体结果见下表5
表5:实施例1-3及对比例1、2的样品皮肤感受使用情况结果统计表:
分析:
实施例1-3例和对比例1-2例制品皮肤感受实验结果体现了,40位使用者使用后透明质酸补水美白面膜精华液,结合隐形蚕丝面膜的面膜膜布,皮肤对抗干燥,补水美白作用明显。
其中,实施例1和对比例1的区别主要是对比例1未添加透明质酸钠,根据皮肤使用前后含水量变化的情况(实施例1:24.9%;对比例1:18.2%),体现透明质酸明显的补水效果;实施例1和对比例2的主要区别为对比例2未采用多重透明质酸钠组合配方,其皮肤使用评价为“不易吸收,表层透明质酸膜,紧绷感明显”。多重透明质酸钠组合的应用,可解决透明质酸钠面膜吸收率低,补水效果不明显的问题。本发明添加了树莓提取物、玫瑰发酵液提取物和烟酰胺等主要的美白功效成分。通过微生物发酵多糖、熊果苷等抗氧化功效明显的成分对自由基的清除和对酪氨酸酶的抑制来达到皮肤美白的功效。
通过皮肤感受试验结果统计数据,以及对使用者皮肤的连续观察,发现实施例试验组的使用者,其皮肤均发生改善,其中实施例1实验组综合评价高达38分(总分40分),符合现代女性对补水美白面膜功效的要求。
以上所述仅为本发明的优选实施例,并非因此限制本发明的专利范围,在不脱离本发明权利要求书中内容的前提下,本技术领域人员做出的很多变化,都应当视为属于本发明创造的保护范围内。
Claims (4)
1.一种透明质酸补水美白面膜,由面膜精华液和面膜膜布构成;其特征在于面膜精华液含有以下重量份的原料组分:四种特定分子量透明质酸钠组合、灵芝提取物0.005-0.04份、黄瓜提取物0.05-0.2份、芦荟提取物0.02-0.2份、马齿苋提取物0.05-0.2份、树莓提取物0.01-0.04份、玫瑰发酵液提取物0.005-0.03份,烟酰胺0.1-1份;稳定剂0.01-0.05份、芳香剂0.001-0.01份,防腐剂0.1-0.35份,增稠剂0.1-0.2份、保湿剂0.05-0.2份和纯水;
所述四种特定分子量透明质酸钠组合为:分子量120k-160kDa的透明质酸钠0.05-0.2份、分子量60k-100kDa的透明质酸钠0.05-0.3份、分子量10k-60kDa的透明质酸钠0.2-0.5份、分子量3k-9kDa的水解透明质酸钠0.1-0.2份。
2.如权利要求1所述的一种透明质酸补水美白面膜,其特征在于,包括以下重量份的原料:分子量120k-160kDa的透明质酸钠0.1份、60k-100kDa的透明质酸钠0.2份、10k-60kDa的透明质酸钠0.4份、3K-9KDa的水解透明质酸钠0.1份、灵芝提取物0.01份、黄瓜提取物0.2份、芦荟提取物0.05份、马齿苋提取物0.1份、树莓提取物0.03份、玫瑰发酵液提取物0.01份,烟酰胺1份;稳定剂0.03份、芳香剂0.002份,防腐剂0.3份,增稠剂0.15份、保湿剂0.1份和纯水。
3.如权利要求1所述透明质酸补水美白面膜,其特征在于,所述稳定剂优选为甘草酸二钾,芳香剂为香精,防腐剂优选为Germall IS-45,增稠剂优选为黄原胶,保湿剂优选为丁二醇。
4.如权利要求1所述透明质酸补水美白面膜,其特征在于,所述面膜膜布为隐形蚕丝面膜。
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Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104971029A (zh) * | 2015-07-31 | 2015-10-14 | 桂林市宏旭生物科技有限公司 | 美白面膜及其制备方法 |
CN105640845A (zh) * | 2016-03-30 | 2016-06-08 | 韩玉逍 | 一种肌龄多效蚕丝面膜液 |
CN107550750A (zh) * | 2016-06-30 | 2018-01-09 | 株式会社爱茉莉太平洋 | 含有不同分子量透明质酸的化妆品组合物 |
CN109330957A (zh) * | 2018-11-25 | 2019-02-15 | 何霖 | 白灵芝美容护肤面膜及洗液 |
-
2020
- 2020-08-14 CN CN202010815767.5A patent/CN112057350A/zh active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104971029A (zh) * | 2015-07-31 | 2015-10-14 | 桂林市宏旭生物科技有限公司 | 美白面膜及其制备方法 |
CN105640845A (zh) * | 2016-03-30 | 2016-06-08 | 韩玉逍 | 一种肌龄多效蚕丝面膜液 |
CN107550750A (zh) * | 2016-06-30 | 2018-01-09 | 株式会社爱茉莉太平洋 | 含有不同分子量透明质酸的化妆品组合物 |
CN109330957A (zh) * | 2018-11-25 | 2019-02-15 | 何霖 | 白灵芝美容护肤面膜及洗液 |
Non-Patent Citations (3)
Title |
---|
张靳绮: "《https://mp.weixin.qq.com/s?src=3×tamp=1664262362&ver=1&signature=OXHEq8UbqGjyP7-b*O5WwAYbfMI3vuY4shN720rF9iMKWmgbhPiFVUEEEEQpUgq0GEx0feVIfX2cFkoBXGhtgT2L*AThOKEMVxLkjqFZZ47hwPJABSa8LqZAxwdCdQ*aq5vkiRB64ZCfJEdsMW9A2Q==》", 14 April 2016 * |
王洪: "《非织造材料及其应用》", 31 July 2020 * |
鹰击长空化学信息: "《https://mp.weixin.qq.com/s/eK0nW8Om_Zo-amT_wE2y2w》", 23 July 2019, 微信公众平台 * |
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