CN112022761A - High-moisturizing whitening repair gel - Google Patents
High-moisturizing whitening repair gel Download PDFInfo
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61K8/27—Zinc; Compounds thereof
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
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- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
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- A61Q19/00—Preparations for care of the skin
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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Abstract
The invention provides a high-moisture-retention whitening repair gel which comprises an active ingredient, a gelling ingredient and a functional auxiliary agent, wherein the mass percentage of the active ingredient, the gelling ingredient and the functional auxiliary agent is respectively 1.5-4.8%, 15-22% and the balance; the gel product is formed by reasonably selecting and matching raw materials and optimizing the proportion, is used for film forming repair of the skin surface, has excellent effects of moisturizing, whitening, wrinkle removing, oxidation resistance and the like, and has strong affinity to the skin, stable overall performance, mildness and safety.
Description
Technical Field
The invention relates to the technical field of cosmetics, in particular to a high-moisturizing whitening repairing gel.
Background
With the increasing pursuit of health and the rapid development of skin medicine, skin care has become a study in modern times, and medical skin care products with higher safety and effectiveness have become an unblocked trend. At present, various cosmetic and skin care products on the market are various in types and have different qualities, and in recent years, the skin itch, stabbing pain, sensitivity and other events caused by the use of cosmetics are frequent, so that consumers are questioned about the quality safety of the cosmetics, and the cosmetics become an attention point of various social circles. Along with more women paying attention to the quality and safety of skin care products, professionals can deeply research and know the structure and physiological action of skin and accessories thereof, and the research on the skin care products and the cosmetics is more specialized and has more pertinence, reliability and competitiveness in performance.
Disclosure of Invention
In view of the above, the invention aims to provide a high-moisturizing whitening repair gel, which is formed into a gel product by reasonably selecting and matching raw materials and optimizing the proportion, is used for film-forming repair of the skin surface, has excellent moisturizing, whitening, wrinkle removing, oxidation resisting and other effects, and has strong affinity to the skin, stable overall performance, mildness and safety.
In order to achieve the purpose, the invention provides the following technical scheme:
a high moisture retention whitening repair gel comprises an active ingredient, a gelling ingredient and a functional auxiliary agent, wherein the mass percentage of the active ingredient, the gelling ingredient and the functional auxiliary agent is respectively 1.5-4.8%, 15-22% and the balance; wherein the active ingredients comprise bitter almond extract, eriodictyol, nano inorganic powder and shea butter.
As a further preferred aspect of the invention, the active ingredients comprise 30-35% of the bitter almond extract, 10-20% of eriodictyol, 10-20% of nano inorganic powder and 25-45% of shea butter.
Further preferably, the nano inorganic powder comprises fumed silica and nano zinc white in a mass ratio of 1: 0.5-1.
As a further preferred aspect of the invention, the gelling component comprises seaweed gel and nano silica sol in a mass ratio of 1: 0.5-0.8.
The functional assistant comprises, by mass, 1.5-3.5% of methyl glucoside sesquistearate, 3-7% of hexanediol, 3-7% of isoprene glycol, 2-5% of octadecanol, 3-6% of hexyldecanol, 2.5-4% of phenyl trimethicone, 6-10% of glycerol and the balance of distilled water.
In the further preferable high moisturizing, whitening and repairing gel of the invention, the bitter almond extract is prepared by the following steps,
1) cleaning semen Armeniacae amarum, drying, pulverizing, sieving with No. 2 sieve, adding ethanol, ultrasonic extracting, centrifuging, and collecting supernatant;
2) adding complex enzyme into the supernatant obtained in the step 1) for enzymolysis, performing microwave enzyme deactivation treatment after the enzymolysis treatment, then performing centrifugation treatment again, and taking the supernatant;
3) adding activated carbon into the supernatant obtained in the step 2), adsorbing and filtering, concentrating the filtrate under reduced pressure until ethanol is completely removed, adding a proper amount of deionized water, uniformly mixing, adding the mixture into a D101 macroporous resin column for elution, and finally concentrating the eluate under reduced pressure until the solvent is completely removed to obtain the compound.
As a further preferred mode of the invention, the ethanol in the step 1) is 40 vt% ethanol solution, and the dosage is 10-12 times of the mass of the bitter almond; ultrasonic extracting at 38-40KHz and 30-35 deg.C; the centrifugal treatment is performed at 3000-3200rpm and 6-6.5cm radius.
As a further preferred mode of the invention, the complex enzyme in the step 2) comprises protease, cellulase and pectinase, and the mass ratio of the protease to the cellulase to the pectinase is 1:2-3: 1-1.5.
As further preferred in the invention, the enzymolysis treatment in the step 2) is carried out at the temperature of between 38 and 40 ℃ for 60 to 100 min; the centrifugation was carried out at 3000rpm and a radius of 6.5 cm.
The invention has the beneficial effects that: the gel product is formed by reasonably selecting and matching raw materials and optimizing the proportion, is used for film-forming repair of the skin surface, has excellent effects of moisturizing, whitening, wrinkle removal, oxidation resistance and the like, and has strong affinity to the skin, stable overall performance, mildness and safety.
According to the preparation method, plant extraction components and inorganic materials are compounded, effective components are loaded and embedded in powder with high specific surface area and mesoporous structure, the preparation method has excellent adhesiveness, slow-release dissolution property and catalytic property, and the powder is uniformly dispersed in gel, so that the surface of the nano inorganic material is favorably combined and modified, the dispersion effect of the nano material is improved, the toughness of gel film forming is improved, the gel film forming is light, thin and unbroken, the overall coverage is strong, the nutrition supplementing effect for relaxing pores is good, and the water locking repairing effect is effectively improved.
The bitter almond extract in the active ingredients contains abundant flavonoids and polyphenols, has excellent antibacterial and antioxidant effects, is very comprehensive in nutrient element composition, can effectively promote skin microcirculation and improve absorption, and greatly improves the skin repairing effect by matching with other active ingredients. Eriodictyol is used for calming the skin, improving the absorption and repair of cuticle, improving the aging resistance of the skin from the inside, matching with the reflection and shielding of nano inorganic powder to external ultraviolet light, remarkably improving the problems of dark and yellow skin and melanin accumulation, achieving quick whitening effect and lasting effect, providing good skin-friendly property for active ingredients as a high-softness emulsion, having good compatibility with the skin, not only quickly supplementing water, improving dry cracking and sunburn, but also having a repairing effect, permeating into the inner layer of the skin, stimulating the growth of cells, having excellent healing effect on acne, red swelling and pox on the surface of the skin, and having efficient and comprehensive repairing effect.
The gel component is formed by combining seaweed gel and nano silica sol, has excellent skin care and beauty effects, simultaneously has good film forming adsorbability, can realize the effect of exchanging and conducting active components and impurities on the surface layer of skin through inorganic powder in the gel component, integrates skin cleaning and maintenance, and greatly improves the application value.
The reasonable extraction process is adopted, the ratio of flavonoids, polyphenols and glycosides in the prepared bitter almond extract is increased by at least 1.5 percent, and the antibacterial, anti-inflammatory and antioxidant effects of the gel are greatly improved.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments of the present invention without any inventive step, are within the scope of the present invention.
Example 1:
a high-moisture-retention whitening repair gel comprises an active ingredient, a gelling ingredient and a functional auxiliary agent, wherein the mass percentage of the active ingredient, the gelling ingredient and the functional auxiliary agent is respectively 3.5 percent, 18 percent and the balance; wherein the content of the first and second substances,
the active ingredients comprise 35% of bitter almond extract, 10% of eriodictyol, 15% of nano inorganic powder and 40% of shea butter.
Further, the nano inorganic powder comprises fumed silica and nano zinc white in a mass ratio of 1: 0.5.
The gelling component comprises seaweed gel and nano silica sol in a mass ratio of 1: 0.5.
The functional assistant comprises, by mass, 1.5-3.5% of methyl glucoside sesquistearate, 3-7% of hexanediol, 3-7% of isoprene glycol, 2-5% of octadecanol, 3-6% of hexyldecanol, 2.5-4% of phenyl trimethicone, 6-10% of glycerol and the balance of distilled water.
The high-moisture-retention whitening and repairing gel is prepared based on the raw materials, wherein the bitter almond extract is prepared by the following steps,
1) cleaning semen Armeniacae amarum, drying, pulverizing, sieving with No. 2 sieve, adding ethanol, ultrasonic extracting, centrifuging, and collecting supernatant;
2) adding complex enzyme into the supernatant obtained in the step 1) for enzymolysis, performing microwave enzyme deactivation treatment after the enzymolysis treatment, then performing centrifugation treatment again, and taking the supernatant;
3) adding activated carbon into the supernatant obtained in the step 2), adsorbing and filtering, concentrating the filtrate under reduced pressure until ethanol is completely removed, adding a proper amount of deionized water, uniformly mixing, adding the mixture into a D101 macroporous resin column for elution, and finally concentrating the eluate under reduced pressure until the solvent is completely removed to obtain the compound.
Wherein, the ethanol in the step 1) is 40 vt% ethanol solution, and the dosage is 10-12 times of the mass of the bitter almond; ultrasonic extraction treatment is carried out at 40KHz and 30 ℃; the centrifugation was carried out at 3000rpm with a radius of 6 cm.
The compound enzyme in the step 2) comprises protease, cellulase and pectinase with the mass ratio of 1:2.5: 1.5; the enzymolysis treatment in the step 2) is carried out at 38-40 ℃ for 80 min; the centrifugation was carried out at 3000rpm and a radius of 6.5 cm.
Example 2:
a high-moisture-retention whitening repair gel comprises an active ingredient, a gelling ingredient and a functional auxiliary agent, wherein the mass percentage of the active ingredient, the gelling ingredient and the functional auxiliary agent is respectively 4.2 percent, 20 percent and the balance; wherein the content of the first and second substances,
the active ingredients comprise bitter almond extract, eriodictyol, nano inorganic powder and shea butter, wherein the active ingredients comprise 30% of bitter almond extract, 15% of eriodictyol, 15% of nano inorganic powder and 40% of shea butter.
Further, the nano inorganic powder comprises fumed silica and nano zinc white in a mass ratio of 1: 0.5.
The gelling component comprises seaweed gel and nano silica sol in a mass ratio of 1: 0.5.
The functional assistant comprises, by mass, 1.5-3.5% of methyl glucoside sesquistearate, 3-7% of hexanediol, 3-7% of isoprene glycol, 2-5% of octadecanol, 3-6% of hexyldecanol, 2.5-4% of phenyl trimethicone, 6-10% of glycerol and the balance of distilled water.
The preparation method of the bitter almond extract is the same as that in example 1.
Wherein, the ethanol in the step 1) is 40 vt% ethanol solution, and the dosage is 10-12 times of the mass of the bitter almond; ultrasonic extraction treatment is carried out at 40KHz and 35 ℃; the centrifugation was carried out at 3200rpm and a radius of 6 cm.
The compound enzyme in the step 2) comprises protease, cellulase and pectinase, and the mass ratio of the protease to the cellulase to the pectinase is 1:3: 1; the enzymolysis treatment in the step 2) is carried out at 38-40 ℃ for 90 min; the centrifugation was carried out at 3000rpm and a radius of 6.5 cm.
Example 3:
a high-moisture-retention whitening repair gel comprises an active ingredient, a gelling ingredient and a functional auxiliary agent, wherein the mass percentage of the active ingredient, the gelling ingredient and the functional auxiliary agent is respectively 4.8 percent, 20 percent and the balance; wherein the content of the first and second substances,
the active ingredients comprise 35% of bitter almond extract, 15% of eriodictyol, 15% of nano inorganic powder and 35% of shea butter.
Further, the nano inorganic powder comprises fumed silica and nano zinc white in a mass ratio of 1: 1.
The gelling component comprises seaweed gel and nano silica sol in a mass ratio of 1: 0.5.
The functional assistant comprises, by mass, 1.5-3.5% of methyl glucoside sesquistearate, 3-7% of hexanediol, 3-7% of isoprene glycol, 2-5% of octadecanol, 3-6% of hexyldecanol, 2.5-4% of phenyl trimethicone, 6-10% of glycerol and the balance of distilled water.
The preparation method of the bitter almond extract is the same as that in example 1.
Wherein, the ethanol in the step 1) is 40 vt% ethanol solution, and the dosage is 10-12 times of the mass of the bitter almond; ultrasonic extraction treatment is carried out at 38KHz and 35 ℃; the centrifugation was carried out at 3200rpm and a radius of 6 cm.
The compound enzyme in the step 2) comprises protease, cellulase and pectinase, and the mass ratio of the protease to the cellulase to the pectinase is 1:2: 1; the enzymolysis treatment in the step 2) is carried out at 38-40 ℃ for 60 min; the centrifugation was carried out at 3000rpm and a radius of 6.5 cm.
Example 4:
a high-moisture-retention whitening repair gel comprises an active ingredient, a gelling ingredient and a functional auxiliary agent, wherein the mass percentage of the active ingredient, the gelling ingredient and the functional auxiliary agent is respectively 3.5 percent, 15 percent and the balance; wherein the content of the first and second substances,
the active ingredients comprise 35% of bitter almond extract, 20% of eriodictyol, 20% of nano inorganic powder and 25% of shea butter.
Further, the nano inorganic powder comprises fumed silica and nano zinc white in a mass ratio of 1: 1.
The gelling component comprises seaweed gel and nano silica sol in a mass ratio of 1: 0.8.
The functional assistant comprises, by mass, 1.5-3.5% of methyl glucoside sesquistearate, 3-7% of hexanediol, 3-7% of isoprene glycol, 2-5% of octadecanol, 3-6% of hexyldecanol, 2.5-4% of phenyl trimethicone, 6-10% of glycerol and the balance of distilled water.
The preparation method of the bitter almond extract is the same as that in example 1.
Wherein, the ethanol in the step 1) is 40 vt% ethanol solution, and the dosage is 10-12 times of the mass of the bitter almond; ultrasonic extraction treatment is carried out at 38KHz and 30 ℃; the centrifugation was carried out at 3200rpm and a radius of 6.5 cm.
The compound enzyme in the step 2) comprises protease, cellulase and pectinase with the mass ratio of 1:2.5: 1; the enzymolysis treatment in the step 2) is carried out at the temperature of 38-40 ℃ for 100 min; the centrifugation was carried out at 3000rpm and a radius of 6.5 cm.
Example 5:
a high-moisture-retention whitening repair gel comprises an active ingredient, a gelling ingredient and a functional auxiliary agent, wherein the mass percentage of the active ingredient, the gelling ingredient and the functional auxiliary agent is respectively 1.5 percent, 20 percent and the balance; wherein the content of the first and second substances,
the active ingredients comprise 35% of bitter almond extract, 15% of eriodictyol, 20% of nano inorganic powder and 30% of shea butter.
Further, the nano inorganic powder comprises fumed silica and nano zinc white in a mass ratio of 1: 1.
The gelling component comprises seaweed gel and nano silica sol in a mass ratio of 1: 0.5.
The functional assistant comprises, by mass, 1.5-3.5% of methyl glucoside sesquistearate, 3-7% of hexanediol, 3-7% of isoprene glycol, 2-5% of octadecanol, 3-6% of hexyldecanol, 2.5-4% of phenyl trimethicone, 6-10% of glycerol and the balance of distilled water.
The preparation method of the bitter almond extract is the same as that in example 1.
Wherein, the ethanol in the step 1) is 40 vt% ethanol solution, and the dosage is 10-12 times of the mass of the bitter almond; ultrasonic extraction treatment is carried out at 40KHz and 30 ℃; the centrifugation was carried out at 3200rpm and a radius of 6.5 cm.
The compound enzyme in the step 2) comprises protease, cellulase and pectinase, and the mass ratio of the protease to the cellulase to the pectinase is 1:3: 1.5; the enzymolysis treatment in the step 2) is carried out at 38-40 ℃ for 60 min; the centrifugation was carried out at 3000rpm and a radius of 6.5 cm.
Example 6:
a high-moisture-retention whitening repair gel comprises an active ingredient, a gelling ingredient and a functional auxiliary agent, wherein the mass percentage of the active ingredient, the gelling ingredient and the functional auxiliary agent is respectively 2.8 percent, 15 percent and the balance; wherein the content of the first and second substances,
the active ingredients comprise bitter almond extract, eriodictyol, nano inorganic powder and shea butter, wherein the active ingredients comprise 30% of bitter almond extract, 20% of eriodictyol, 15% of nano inorganic powder and 35% of shea butter.
Further, the nano inorganic powder comprises fumed silica and nano zinc white in a mass ratio of 1: 1.
The gelling component comprises seaweed gel and nano silica sol in a mass ratio of 1: 0.5.
The functional assistant comprises, by mass, 1.5-3.5% of methyl glucoside sesquistearate, 3-7% of hexanediol, 3-7% of isoprene glycol, 2-5% of octadecanol, 3-6% of hexyldecanol, 2.5-4% of phenyl trimethicone, 6-10% of glycerol and the balance of distilled water.
The preparation method of the bitter almond extract is the same as that in example 1.
Wherein, the ethanol in the step 1) is 40 vt% ethanol solution, and the dosage is 10-12 times of the mass of the bitter almond; ultrasonic extraction treatment is carried out at 38KHz and 30 ℃; the centrifugation was carried out at 3200rpm and a radius of 6.5 cm.
The compound enzyme in the step 2) comprises protease, cellulase and pectinase, and the mass ratio of the protease to the cellulase to the pectinase is 1:2: 1.5; the enzymolysis treatment in the step 2) is carried out at 38-40 ℃ for 80 min; the centrifugation was carried out at 3000rpm and a radius of 6.5 cm.
Example 7:
a high-moisture-retention whitening repair gel comprises an active ingredient, a gelling ingredient and a functional auxiliary agent, wherein the mass percentage of the active ingredient, the gelling ingredient and the functional auxiliary agent is respectively 3.6 percent, 22 percent and the balance; wherein the content of the first and second substances,
the active ingredients comprise bitter almond extract, eriodictyol, nano inorganic powder and shea butter, wherein the active ingredients comprise 30% of bitter almond extract, 15% of eriodictyol, 10% of nano inorganic powder and 45% of shea butter.
Further, the nano inorganic powder comprises fumed silica and nano zinc white in a mass ratio of 1: 1.
The gelling component comprises seaweed gel and nano silica sol in a mass ratio of 1: 0.5.
The functional assistant comprises, by mass, 1.5-3.5% of methyl glucoside sesquistearate, 3-7% of hexanediol, 3-7% of isoprene glycol, 2-5% of octadecanol, 3-6% of hexyldecanol, 2.5-4% of phenyl trimethicone, 6-10% of glycerol and the balance of distilled water.
The preparation method of the bitter almond extract is the same as that in example 1.
Wherein, the ethanol in the step 1) is 40 vt% ethanol solution, and the dosage is 10-12 times of the mass of the bitter almond; ultrasonic extraction treatment is carried out at 40KHz and 35 ℃; the centrifugation was carried out at 3000rpm with a radius of 6.5 cm.
The compound enzyme in the step 2) comprises protease, cellulase and pectinase, and the mass ratio of the protease to the cellulase to the pectinase is 1:2: 1; the enzymolysis treatment in the step 2) is carried out at the temperature of 38-40 ℃ for 100 min; the centrifugation was carried out at 3000rpm and a radius of 6.5 cm.
Comparative example 1:
based on the ratio of the components in example 1, the active ingredient was removed and the other conditions were not changed to prepare control 1.
Comparative example 2:
based on the ratio of the components in example 1, the almond extract was removed from the active ingredient, and the other conditions were unchanged, to prepare control 2.
Comparative example 2:
based on the ratio of the components in example 1, the nano inorganic powder in the active ingredient was removed, and the other conditions were unchanged, to obtain control 3.
The skin care effect evaluation is carried out on the products of the above examples, and the test subjects: 400 healthy women aged 28 to 45 years were randomly divided into 10 groups of 40 persons, each of the groups 1 to 7 using the products of examples 1 to 7, respectively, and the groups 8 to 10 using the products of comparative examples 1 to 3.
The test method comprises the following steps: before the gel is coated, a subject uses the same mild cleanser to clean the face, then the subject coats the corresponding gel product (1-3g, the thickness is not more than 0.2mm, the gel product can be independently coated on a certain part according to the coating area) on the face, after the gel product is uniformly spread, the gel product is kept for 8-10min and then taken off, the use frequency is once every morning and night, and the gel product is continuously used for 4 weeks. Insolation was avoided during the test period, and no other cosmetics, drugs and health products were used.
The test results are given in the following table (data for macroscopic efficacy):
wrinkle (wrinkle) | Comedo | White skin | Mottled pox mark | Smooth gloss | |
Examples | 77.5 | 82.5 | 100 | 87.5 | 100 |
Comparative example 1 | 27.5 | 25 | 45 | 25 | 60 |
Comparative example 2 | 40 | 37.5 | 65 | 42.5 | 72.5 |
Comparative example 3 | 37.5 | 42.5 | 57.5 | 45 | 85 |
Wherein, the data of the examples are the comprehensive evaluation values of the examples 1 to 7.
According to the table, the skin care cream has an excellent skin care effect, can obviously improve wrinkles, comedones, mottle and acne marks and the like, is quick in effect, small in irritation, and capable of permeating into essential problems of skin, optimizing skin quality, whitening, ruddy and glossy.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other identical elements in a process, method, article, or apparatus that comprises the element.
The above examples are only intended to illustrate the technical solution of the present invention, but not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions of the embodiments of the present invention.
Claims (9)
1. The high-moisture-retention whitening repair gel is characterized in that: comprises active ingredients, gelling ingredients and functional additives, wherein the mass percentage of the active ingredients, the gelling ingredients and the functional additives is 1.5-4.8 percent, 15-22 percent and the balance respectively; wherein the active ingredients comprise bitter almond extract, eriodictyol, nano inorganic powder and shea butter.
2. The high moisturizing whitening repair gel according to claim 1, characterized in that: the active ingredients comprise 30-35% of bitter almond extract, 10-20% of eriodictyol, 10-20% of nano inorganic powder and 25-45% of shea butter.
3. The high moisturizing whitening repair gel according to claim 2, characterized in that: the nano inorganic powder comprises fumed silica and nano zinc white in a mass ratio of 1: 0.5-1.
4. The high moisturizing whitening repair gel according to claim 1, characterized in that: the gelling component comprises seaweed gel and nano silica sol in a mass ratio of 1: 0.5-0.8.
5. The high moisturizing whitening repair gel according to claim 1, characterized in that: the functional assistant comprises, by mass, 1.5-3.5% of methyl glucoside sesquistearate, 3-7% of hexanediol, 3-7% of isoprene glycol, 2-5% of octadecanol, 3-6% of hexyldecanol, 2.5-4% of phenyl trimethicone, 6-10% of glycerol and the balance of distilled water.
6. The high moisturizing whitening repair gel according to any one of claims 1 to 5, wherein: the preparation method of the bitter almond extract comprises the following steps,
1) cleaning semen Armeniacae amarum, drying, pulverizing, sieving with No. 2 sieve, adding ethanol, ultrasonic extracting, centrifuging, and collecting supernatant;
2) adding complex enzyme into the supernatant obtained in the step 1) for enzymolysis, performing microwave enzyme deactivation treatment after the enzymolysis treatment, then performing centrifugation treatment again, and taking the supernatant;
3) adding activated carbon into the supernatant obtained in the step 2), adsorbing and filtering, concentrating the filtrate under reduced pressure until ethanol is completely removed, adding a proper amount of deionized water, uniformly mixing, adding the mixture into a D101 macroporous resin column for elution, and finally concentrating the eluate under reduced pressure until the solvent is completely removed to obtain the compound.
7. The high moisturizing whitening repair gel according to claim 6, characterized in that: in the step 1), the ethanol is 40 vt% ethanol solution, the dosage is 10-12 times of the quality of bitter almond; ultrasonic extracting at 38-40KHz and 30-35 deg.C; the centrifugal treatment is performed at 3000-3200rpm and 6-6.5cm radius.
8. The high moisturizing whitening repair gel according to claim 6, characterized in that: the complex enzyme in the step 2) comprises protease, cellulase and pectinase, and the mass ratio of the protease to the cellulase to the pectinase is 1:2-3: 1-1.5.
9. The high moisturizing whitening repair gel according to claim 6, characterized in that: the enzymolysis treatment in the step 2) is carried out at the temperature of 38-40 ℃ for 60-100 min; the centrifugation was carried out at 3000rpm and a radius of 6.5 cm.
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN117174220A (en) * | 2023-11-02 | 2023-12-05 | 南通逸美医疗科技有限公司 | Design optimization method and system for collagen gel |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN117174220A (en) * | 2023-11-02 | 2023-12-05 | 南通逸美医疗科技有限公司 | Design optimization method and system for collagen gel |
CN117174220B (en) * | 2023-11-02 | 2023-12-22 | 南通逸美医疗科技有限公司 | Design optimization method and system for collagen gel |
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