CN111991917A - Device for preparing coagulation factor concentrate from blood sample - Google Patents
Device for preparing coagulation factor concentrate from blood sample Download PDFInfo
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- CN111991917A CN111991917A CN202010824635.9A CN202010824635A CN111991917A CN 111991917 A CN111991917 A CN 111991917A CN 202010824635 A CN202010824635 A CN 202010824635A CN 111991917 A CN111991917 A CN 111991917A
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- sleeve
- cylindrical container
- coagulation factor
- hole
- blood sample
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D36/00—Filter circuits or combinations of filters with other separating devices
- B01D36/04—Combinations of filters with settling tanks
- B01D36/045—Combination of filters with centrifugal separation devices
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Abstract
The invention discloses a device for preparing a coagulation factor concentrate from a blood sample, and relates to the technical field of medical instruments. The blood sampling device comprises a cylindrical container, a pushing device, a blood sampling device and an injector, wherein the cylindrical container is of a cavity structure, the blood sampling device is arranged on one surface of the cylindrical container, the pushing device is arranged on the upper surface of the cylindrical container, and the injector is arranged in the pushing device. According to the invention, a closed extraction environment is provided for the blood sample in an integrated manner of storage, centrifugation and extraction, sample pollution is avoided, the integrity of the sample is ensured, various compounds are conveniently added through the first filter and the second filter, the preparation efficiency is improved, and the extraction of the coagulation factor concentrate is facilitated through the built-in injector structure, so that sample pollution is avoided.
Description
Technical Field
The invention belongs to the technical field of medical instruments, and particularly relates to a device for preparing a coagulation factor concentrate from a blood sample.
Background
A method for preparing a coagulation factor such as fibrinogen, fibronectin from a blood sample by subjecting the blood sample to centrifugal separation, the blood sample being separated into a plasma fraction and a cell-containing fraction, the coagulation factor being subsequently extracted from the plasma fraction by cryoprecipitation or by means of a coagulation promoting agent such as ethanol, the extract containing mainly fibrinogen and, with the addition of a suitable enzyme such as thrombin, it can be used, for example, as a tissue glue for surgical wounds, the fibrinogen forming a similarly natured fibrin when bound to thrombin, the fibrin forming an insoluble network of fibrous material which forms a tissue glue which binds to the wound surface during wound healing. Therefore, a coagulation factor concentrate mainly containing fibrinogen performs extremely well for surgical wound healing.
The existing blood sample preparation method is easy to cause infection and destroy the integrity of the sample through multiple transfers, and simultaneously, blood is easy to coagulate, so that all samples cannot be utilized, and the rest samples are stuck on the wall of a container to cause waste.
Disclosure of Invention
The invention aims to provide a device for preparing a coagulation factor concentrate from a blood sample, which provides a closed extraction environment for the blood sample in a mode of integrating storage, centrifugation and extraction, avoids sample pollution and ensures the integrity of the sample.
In order to solve the technical problems, the invention is realized by the following technical scheme:
the invention relates to a device for preparing a coagulation factor concentrate from a blood sample, which comprises a cylindrical container, a pushing device, a blood sampling device and an injector, wherein the cylindrical container is of a cavity structure, the blood sampling device is arranged on one surface of the cylindrical container, the pushing device is arranged on the upper surface of the cylindrical container, and the injector is arranged in the pushing device.
Preferably, a first through hole is formed in one surface of the cylindrical container, a first connecting piece is mounted on one surface of the first through hole to facilitate communication with an external device, a second through hole is formed in the other surface of the cylindrical container, a second connecting piece is mounted on one surface of the second through hole, a second filter is mounted at one end of the second connecting piece, and a vehicle such as alcohol in the form of ethanol is added through the second filter to promote precipitation of the coagulation factor concentrate.
Preferably, surface mounting has the sealing member on the cylinder container, sealing member week side is provided with solid fixed ring, gu fixed ring upper surface welding has a plurality of handles, the handle is "L" shape structure, makes things convenient for operating personnel to snatch, the sealing member upper surface is provided with the opening, the inside sleeve that is provided with of opening, telescopic diameter suits with the opening diameter, a plurality of handles one end weld with sleeve week side mutually.
Preferably, the sleeve is the through-hole structure, surface mounting has the apron on the sleeve, first piston is installed to the sleeve other end, sleeve internally mounted has the syringe, makes things convenient for the extraction of coagulation factor concentrate, the block piece is installed to syringe one side, the block piece is "L" shape pipe, block piece one end and install inside first piston, the block piece other end extends to sleeve one end, block piece one end and be provided with the third through-hole, enter into the second compartment from first compartment through blocking piece control blood sample.
Preferably, the first piston divides the interior of the cylindrical container into a first compartment and a second compartment, the first compartment is communicated with the first through hole, the second compartment is communicated with the second through hole, a first channel and a second channel are arranged in the first piston, one end of the blocking piece is placed in the first channel, and the third through hole is matched with the first channel.
Preferably, the syringe includes syringe sleeve pipe, piston rod and pipe, syringe sleeve pipe internally mounted has the piston rod, the second piston is installed to piston rod one end, syringe sleeve pipe one end is connected with the pipe, the pipe is linked together through second passageway and second compartment inside, conveniently draws the coagulation factor concentrate to syringe inside.
Preferably, the blood sampling device comprises a hose, a first filter and a needle head, one end of the hose is connected with the first connecting piece, the needle head is installed at the other end of the hose, and the first filter is installed on the peripheral side face of the hose.
The invention has the following beneficial effects:
1. the invention provides a closed extraction environment for the blood sample by integrating storage, centrifugation and extraction, thereby avoiding sample pollution and ensuring the integrity of the sample.
2. According to the invention, through the structures of the first filter and the second filter, various compounds can be conveniently added, and the preparation efficiency is improved.
3. The invention is convenient for the extraction of the coagulation factor concentrate by the structure of the built-in injector, and avoids the sample pollution.
Of course, it is not necessary for any product in which the invention is practiced to achieve all of the above-described advantages at the same time.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings used in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art that other drawings can be obtained according to the drawings without creative efforts.
FIG. 1 is a schematic diagram of the construction of an apparatus for preparing a coagulation factor concentrate from a blood sample according to the present invention;
FIG. 2 is a schematic diagram of a front view of an apparatus for preparing a coagulation factor concentrate from a blood sample according to the present invention;
FIG. 3 is a schematic top view of an apparatus for preparing a coagulation factor concentrate from a blood sample according to the present invention;
FIG. 4 is a schematic diagram showing the internal structure of an apparatus for preparing a coagulation factor concentrate from a blood sample according to the present invention;
FIG. 5 is a schematic view of a blocker according to the present invention.
In the drawings, the components represented by the respective reference numerals are listed below:
1. a cylindrical container; 2. a pushing device; 3. a blood collection device; 4. a fixing ring; 5. a handle; 6. a seal member; 7. an opening; 8. a sleeve; 9. a cover plate; 10. a first through hole; 11. a first connecting member; 12. a second through hole; 13. a second connecting member; 14. a first filter; 15. a hose; 16. a needle head; 17. a second filter; 18. a first piston; 19. a first compartment; 20. a second compartment; 21. an injector; 22. a syringe cannula; 23. a piston rod; 24. a conduit; 25. a blocking member; 26. a third through hole; 27. a first channel; 28. a second channel; 29. a second piston.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In the description of the present invention, it is to be understood that the terms "upper", "middle", "outer", "inner", and the like, indicate orientations or positional relationships, are used for convenience in describing the present invention and simplifying the description, but do not indicate or imply that the referenced components or elements must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention.
The first embodiment is as follows:
referring to fig. 1-5, the present invention is an apparatus for preparing a coagulation factor concentrate from a blood sample, comprising a cylindrical container 1, a pushing device 2, a blood sampling device 3 and a syringe 21, wherein the cylindrical container 1 is a hollow structure, the blood sampling device 3 is mounted on one surface of the cylindrical container 1, the pushing device 2 is arranged on the upper surface of the cylindrical container 1, and the syringe 21 is mounted inside the pushing device 2.
A first through hole 10 is formed in one surface of a cylindrical container 1, a first connecting piece 11 is installed on one surface of the first through hole 10 to facilitate communication with an external device, a second through hole 12 is formed in the other surface of the cylindrical container 1, a second connecting piece 13 is installed on one surface of the second through hole 12, a second filter 17 is installed at one end of the second connecting piece 13, and a medium such as alcohol in the form of ethanol is added through the second filter 17 to promote precipitation of coagulation factor concentrate.
Surface mounting has sealing member 6 on the cylinder container 1, and 6 week side faces of sealing member are provided with solid fixed ring 4, and solid fixed ring 4 upper surface welding has a plurality of handles 5, and handle 5 is "L" shape structure, makes things convenient for operating personnel to snatch, and 6 upper surfaces of sealing member are provided with opening 7, and opening 7 is inside to be provided with sleeve 8, and sleeve 8's diameter suits with opening 7 diameter, and a plurality of handles 5 one end weld with 8 week side faces of sleeve mutually.
The first piston 18 divides the interior of the cylindrical container 1 into a first compartment 19 and a second compartment 20, the first compartment 19 is communicated with the first through hole 10, the second compartment 20 is communicated with the second through hole 12, the first piston 18 is internally provided with a first passage 27 and a second passage 28, one end of the blocking member 25 is placed in the first passage 27, and the third through hole 26 is mutually matched with the first passage 27.
The device is characterized in that the injector 21 comprises an injector sleeve 22, a piston rod 23 and a conduit 24, the piston rod 23 is arranged in the injector sleeve 22, a second piston 29 is arranged at one end of the piston rod 23, the conduit 24 is connected to one end of the injector sleeve 22, and the conduit 24 is communicated with the interior of the second compartment 20 through a second channel 28, so that the blood coagulation factor concentrate can be conveniently extracted into the injector 21.
The blood sampling device 3 comprises a hose 15, a first filter 14 and a needle 16, wherein one end of the hose 15 is connected with the first connecting piece 11, the needle 16 is arranged at the other end of the hose 15, and the first filter 14 is arranged on the peripheral side surface of the hose 15.
The second embodiment is as follows:
referring to fig. 1-5, the present invention is an apparatus for preparing a coagulation factor concentrate from a blood sample, using the method comprising: first of all by pushing the pushing means 2 to bring the first piston 18 into the bottom of the second compartment 20, establishing a depression inside the first compartment 19, then the operator automatically takes the blood sample inside the first compartment 19 through the needle 16, injecting an anticoagulant inside the first compartment 19 before or at the same time as the transfer of the blood sample through the first filter 14; after the blood sample is taken, the device is placed into a centrifuge for centrifugation, the centrifugation causes the blood sample in the first compartment 19 to be divided into a plasma part and a cell-containing part, the plasma part is close to the first piston 18, the third through hole 26 is changed in direction by rotating the blocking member 25, thereby opening the first passage 27, then the handle 5 is pulled to pull the first piston 18 until the plasma part is transferred to the inside of the second compartment 20 through the first passage 27, the precipitation of the coagulation factor in the second compartment 20 is promoted by cooling the coagulation factor in the plasma part or adding a vehicle such as alcohol in the form of ethanol through the second filter 17, then the first piston 18 is pushed to discharge the plasma part remaining in the second compartment 20 into the first compartment 19 through the first passage 27, and then the first passage 27 is closed by rotating the blocking member 25; through the heating device bottom, make the inside precipitate liquefaction of second compartment 20, open apron 9, pulling piston rod 23 is that the liquefaction precipitate draws to syringe 21 inside through pipe 24, through storage, centrifugation and the integrative mode of extraction, for blood sample provides a confined environment of drawing, avoids the sample to pollute, guarantees the integrality of sample.
In the description herein, references to the description of "one embodiment," "an example," "a specific example" or the like are intended to mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
The preferred embodiments of the invention disclosed above are intended to be illustrative only. The preferred embodiments are not intended to be exhaustive or to limit the invention to the precise embodiments disclosed. Obviously, many modifications and variations are possible in light of the above teaching. The embodiments were chosen and described in order to best explain the principles of the invention and the practical application, to thereby enable others skilled in the art to best utilize the invention. The invention is limited only by the claims and their full scope and equivalents.
Claims (7)
1. An apparatus for preparing a coagulation factor concentrate from a blood sample, comprising a cylindrical container (1), a pushing means (2), a blood sampling means (3) and a syringe (21), characterized in that: the blood sampling device is characterized in that the cylindrical container (1) is of a cavity structure, a blood sampling device (3) is mounted on one surface of the cylindrical container (1), a pushing device (2) is arranged on the upper surface of the cylindrical container (1), and an injector (21) is mounted inside the pushing device (2).
2. The device for preparing a coagulation factor concentrate from a blood sample according to claim 1, wherein a first through hole (10) is formed in one surface of the cylindrical container (1), a first connecting member (11) is mounted on one surface of the first through hole (10), a second through hole (12) is formed in the other surface of the cylindrical container (1), a second connecting member (13) is mounted on one surface of the second through hole (12), and a second filter (17) is mounted at one end of the second connecting member (13).
3. The device for preparing the coagulation factor concentrate from the blood sample according to claim 1, wherein a sealing element (6) is surface-mounted on the cylindrical container (1), a fixing ring (4) is arranged on the peripheral side of the sealing element (6), a plurality of handles (5) are welded on the upper surface of the fixing ring (4), the handles (5) are in an L-shaped structure, an opening (7) is arranged on the upper surface of the sealing element (6), a sleeve (8) is arranged inside the opening (7), the diameter of the sleeve (8) is adapted to the diameter of the opening (7), and one end of each handle (5) is welded on the peripheral side of the sleeve (8).
4. The device for preparing the coagulation factor concentrate from the blood sample as claimed in claim 3, wherein the sleeve (8) is a through hole structure, the cover plate (9) is mounted on the upper surface of the sleeve (8), the first piston (18) is mounted at the other end of the sleeve (8), the syringe (21) is mounted in the sleeve (8), the blocking member (25) is mounted at one side of the syringe (21), the blocking member (25) is an "L" -shaped circular tube, one end of the blocking member (25) is mounted in the first piston (18), the other end of the blocking member (25) extends to one end of the sleeve (8), and the third through hole (26) is arranged at one end of the blocking member (25).
5. The device for preparing a coagulation factor concentrate from a blood sample according to claim 4, wherein the first piston (18) divides the interior of the cylindrical container (1) into a first compartment (19) and a second compartment (20), the first compartment (19) is communicated with the first through hole (10), the second compartment (20) is communicated with the second through hole (12), the first piston (18) is internally provided with a first passage (27) and a second passage (28), one end of the blocking member (25) is placed in the first passage (27), and the third through hole (26) is mutually matched with the first passage (27).
6. The device for preparing a coagulation factor concentrate from a blood sample according to claim 1, wherein the syringe (21) comprises a syringe sleeve (22), a piston rod (23) and a conduit (24), the syringe sleeve (22) is internally provided with the piston rod (23), one end of the piston rod (23) is provided with a second piston (29), one end of the syringe sleeve (22) is connected with the conduit (24), and the conduit (24) is communicated with the inside of the second compartment (20) through a second channel (28).
7. The device according to claim 1, wherein the blood sampling device (3) comprises a flexible tube (15), a first filter (14) and a needle (16), one end of the flexible tube (15) is connected with the first connector (11), the other end of the flexible tube (15) is provided with the needle (16), and the peripheral side of the flexible tube (15) is provided with the first filter (14).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010824635.9A CN111991917A (en) | 2020-08-17 | 2020-08-17 | Device for preparing coagulation factor concentrate from blood sample |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010824635.9A CN111991917A (en) | 2020-08-17 | 2020-08-17 | Device for preparing coagulation factor concentrate from blood sample |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN111991917A true CN111991917A (en) | 2020-11-27 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010824635.9A Pending CN111991917A (en) | 2020-08-17 | 2020-08-17 | Device for preparing coagulation factor concentrate from blood sample |
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| CN (1) | CN111991917A (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1056632A (en) * | 1990-05-14 | 1991-12-04 | 于内斯有限公司 | The device of preparation such as fibrinogenic concentrate of coagulation factors from blood sample |
| CN105214343A (en) * | 2015-10-26 | 2016-01-06 | 张家港高品诚医械科技有限公司 | A kind of extraction suit of platelet rich plasma |
-
2020
- 2020-08-17 CN CN202010824635.9A patent/CN111991917A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1056632A (en) * | 1990-05-14 | 1991-12-04 | 于内斯有限公司 | The device of preparation such as fibrinogenic concentrate of coagulation factors from blood sample |
| CN105214343A (en) * | 2015-10-26 | 2016-01-06 | 张家港高品诚医械科技有限公司 | A kind of extraction suit of platelet rich plasma |
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Application publication date: 20201127 |
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| RJ01 | Rejection of invention patent application after publication |