CN111956686A - Honey enema and preparation method thereof - Google Patents

Honey enema and preparation method thereof Download PDF

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Publication number
CN111956686A
CN111956686A CN202010840553.3A CN202010840553A CN111956686A CN 111956686 A CN111956686 A CN 111956686A CN 202010840553 A CN202010840553 A CN 202010840553A CN 111956686 A CN111956686 A CN 111956686A
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Prior art keywords
soluble
honey
oil
enema
coating layer
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Pending
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CN202010840553.3A
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Chinese (zh)
Inventor
刘超奇
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Wuhan Natural Innovation Technology Co ltd
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Wuhan Natural Innovation Technology Co ltd
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Priority to CN202010840553.3A priority Critical patent/CN111956686A/en
Publication of CN111956686A publication Critical patent/CN111956686A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/14Alkali metal chlorides; Alkaline earth metal chlorides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0031Rectum, anus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10Laxatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Abstract

The invention discloses a honey enema and a preparation method thereof, wherein the honey enema comprises the following components: a soluble coating layer; the liquid preparation is filled in the coating layer; the lubricant is coated on the surface of the coating layer; the liquid preparation consists of honey, acetic acid, physiological saline and auxiliary materials; the coating layer comprises a soluble shaping film and a water-soluble coating layer coated on the outer surface of the shaping layer; the shaping layer is an oil-soluble shaping film, and the liquid preparation is filled in the inner cavity of the oil-soluble shaping film; the lubricant is coated on the surface of the water-soluble coating layer; this honey glycerine enema adopts honey, acetic acid and normal saline as the main materials, not only it has better lubrication action, still has the function of nourishing the intestinal, and is milder during the use, adopts the formula material that can dissolve to pack, directly during the use fill in the intestinal can with it, it is more convenient to use, can not produce situations such as scratch health, the result of use is safe, effective.

Description

Honey enema and preparation method thereof
Technical Field
The invention relates to the technical field of medicines, in particular to honey enema and a preparation method thereof.
Background
Constipation refers to the condition of stool staying in the colon for a long time, with reduced water content, dry and hard, and difficult discharge. The current general diagnosis standard of constipation is (1) the defecation frequency is reduced; (2) difficult defecation or incomplete defecation; (3) the feces are dry and hard. Constipation can be diagnosed if 1 or a combination of 1 to 3 items are present. Usually with a reduced defecation frequency. Generally, constipation may occur once every 2 to 3 days or more, and attention needs to be paid. Mental and psychological disorders such as insomnia, dysphoria, depression, anxiety and the like easily appear in constipation; nausea and anorexia are caused by abdominal fullness; may induce anal fissure, hemorrhoid, etc.; if cardiovascular and cerebrovascular diseases exist, constipation can become a fatal risk factor, abdominal pressure can be continuously increased for a long time in defecation, the quantity of return blood is reduced, intracranial pressure is continuously increased, and cardiac arrhythmia and cerebrovascular accidents are easily caused; may also induce colon cancer, liver disease, and breast disease.
With the physiological characteristics of accelerated life rhythm, psychosocial factors, pregnancy or age increase and the like, the constipation prevalence rate in China shows a rising trend. Pregnant women, sedentary workers, the elderly and the like are high-incidence people with constipation. According to incomplete statistics, constipation is very common in the elderly over 60 years old, and the incidence rate is about 22%. Constipation is also common in pregnant women due to reduced activity, physiological structure and hormone secretion during pregnancy, and about 38% of pregnant women will suffer from constipation through research.
At present, most of the treatment or improvement modes for constipation are oral Chinese and western medicines or external medicines.
The existing external medicine is mainly liquid enema which is composed of glycerin and water components and is poured into the intestinal tract through the liquid enema to stimulate the intestinal tract and lubricate the stool. The existing enema only has the functions of stimulating intestinal tracts and smaller lubrication, has single function, can be used by special auxiliary equipment when in use, is very troublesome to operate, can scratch the body easily when in use, and has very poor use effect.
Disclosure of Invention
In order to solve the problems, the invention provides honey enema and a preparation method thereof.
The technical scheme adopted by the invention is as follows: a honey enema comprising:
a soluble coating layer;
the liquid preparation is filled in the coating layer;
the lubricant is coated on the surface of the coating layer;
the liquid preparation consists of honey, acetic acid, physiological saline and auxiliary materials;
the coating layer comprises a soluble shaping film and a water-soluble coating layer coated on the outer surface of the shaping layer; the shaping layer is an oil-soluble shaping film, and the liquid preparation is filled in the inner cavity of the oil-soluble shaping film; the lubricant is coated on the surface of the water-soluble coating layer.
Furthermore, the diameter of one end of the oil-soluble shaping film is gradually increased towards the other end, and the end part of the small-diameter end is of a round-head structure.
Further, the auxiliary material is an active agent.
Further, the active agent comprises one or more of extracts of scutellaria baicalensis, phellodendron amurense, sophora flavescens and bupleurum chinense.
Further, the active agent comprises one or more of extracts of rhizoma Atractylodis Macrocephalae, radix Scutellariae, radix Glycyrrhizae, radix Angelicae sinensis, and radix Salviae Miltiorrhizae.
In another aspect of the present invention, a method for preparing the honey glycerine enema in the above technical scheme is provided, which comprises the following steps:
(a) mixing honey, acetic acid, physiological saline and auxiliary materials to prepare a liquid preparation;
(b) preparing an oil-soluble shaping film from the oil-soluble material through a die;
(c) pouring the liquid preparation into an oil-soluble shaping film and packaging;
(d) covering the outer surface of the packaged oil-soluble shaping film with a water-soluble coating;
(e) and applying a lubricant to the outside of the water-soluble coating.
Further, the step of covering the outer surface of the oil-soluble shaping film with a water-soluble coating is to put the oil-soluble shaping film into a coating machine for coating.
Further, the method also comprises the step of packaging the honey glycerine enema.
Compared with the prior art, the invention has the following beneficial effects:
the honey enema provided by the invention is prepared from honey, normal saline and acetic acid as main materials, has a better lubricating effect, has a function of nourishing intestinal tracts, is milder when being used, is assisted by scutellaria baicalensis, golden cypress, radix sophorae flavescentis, radix bupleuri, bighead atractylodes rhizome, scutellaria baicalensis, liquorice, angelica sinensis, salvia miltiorrhiza and the like, can be used for relieving constipation better, and can be used for preventing and treating symptoms such as infection and ulcer caused by anal fissure and haemorrhoids.
The honey enema provided by the invention is packaged by adopting a soluble material, and is directly plugged into an intestinal tract when in use, so that the honey enema is more convenient to use, does not scratch the body and the like, and is safe and effective in use effect.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the structures shown in the drawings without creative efforts.
FIG. 1 is a schematic structural diagram of a honey enema in the invention;
figure 2 is a flow chart of the preparation of the honey glycerine enema of the invention.
The implementation, functional features and advantages of the objects of the present invention will be further explained with reference to the accompanying drawings.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
It should be noted that all the directional indicators (such as up, down, left, right, front, and rear … …) in the embodiment of the present invention are only used to explain the relative position relationship between the components, the movement situation, etc. in a specific posture (as shown in the drawing), and if the specific posture is changed, the directional indicator is changed accordingly.
In addition, the descriptions related to "first", "second", etc. in the present invention are for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In addition, technical solutions between various embodiments may be combined with each other, but must be realized by a person skilled in the art, and when the technical solutions are contradictory or cannot be realized, such a combination should not be considered to exist, and is not within the protection scope of the present invention.
A Mel glycerine enema as shown in figure 1 comprises soluble coating layer, liquid preparation, and lubricant; the liquid preparation is filled in the coating layer; the lubricant is coated on the surface of the coating layer; the coating layer comprises a soluble shaping film and a water-soluble coating layer coated on the outer surface of the shaping layer; the shaping layer is an oil-soluble shaping film, and the liquid preparation is filled in the inner cavity of the oil-soluble shaping film; the lubricant is coated on the surface of the water-soluble coating layer.
One end of the oil-soluble shaping film is gradually enlarged towards the other end, and the end part of the small-diameter end is of a round-head structure.
The liquid preparation consists of honey, acetic acid, physiological saline and auxiliary materials;
in this embodiment, the excipient is an active agent; the active agent comprises one or more of Scutellariae radix, cortex Phellodendri, radix Sophorae Flavescentis, and bupleuri radix extract.
Further, the active agent comprises one or more of extracts of rhizoma Atractylodis Macrocephalae, radix Scutellariae, radix Glycyrrhizae, radix Angelicae sinensis, and radix Salviae Miltiorrhizae.
The honey enema is prepared from main materials of honey, normal saline and acetic acid, has better lubricating effect and a function of nourishing intestinal tracts compared with the mode that the traditional enema is prepared from materials such as glycerol or sorbitol, is milder in use, is assisted by important materials such as scutellaria baicalensis, golden cypress, radix sophorae flavescentis, radix bupleuri, bighead atractylodes rhizome, scutellaria baicalensis, liquorice, angelica sinensis and salvia miltiorrhiza, can better relieve constipation, and can prevent and treat symptoms such as infection and ulcer caused by anal fissure and haemorrhoids.
The preparation method of the honey glycerine enema of the invention is shown in figure 2 and comprises the following steps:
(a) mixing honey, acetic acid, physiological saline and auxiliary materials to prepare a liquid preparation;
(b) preparing an oil-soluble shaping film from the oil-soluble material through a die;
(c) pouring the liquid preparation into an oil-soluble shaping film and packaging;
(d) covering the outer surface of the packaged oil-soluble shaping film with a water-soluble coating;
(e) and applying a lubricant to the outside of the water-soluble coating.
The step of covering the outer surface of the oil-soluble shaping film with a water-soluble coating is to put the oil-soluble shaping film into a coating machine for coating.
The method also comprises the step of packaging the honey glycerine enema.
Example 1
(a) Mixing honey, acetic acid, normal saline, bighead atractylodes rhizome and scutellaria baicalensis to prepare a liquid preparation;
(b) preparing an oil-soluble shaping film from the oil-soluble material through a die;
(c) pouring the liquid preparation into an oil-soluble shaping film and packaging;
(d) covering the outer surface of the packaged oil-soluble shaping film with a water-soluble coating;
(e) and coating the lubricating oil on the outer side of the water-soluble coating.
(f) And packaging the honey glycerine enema.
Example 2
(a) Mixing honey, acetic acid, normal saline, bighead atractylodes rhizome and scutellaria baicalensis to prepare a liquid preparation;
(b) preparing an oil-soluble shaping film from the oil-soluble material through a die;
(c) pouring the liquid preparation into an oil-soluble shaping film and packaging;
(d) putting the packaged oil-soluble shaping film outside a coating machine for water-soluble coating;
(e) and coating the lubricating oil on the outer side of the water-soluble coating.
(f) And packaging the honey glycerine enema.
Example 3
(a) Mixing honey, acetic acid, normal saline, phellodendron and radix bupleuri to prepare a liquid preparation;
(b) preparing an oil-soluble shaping film from the oil-soluble material through a die;
(c) pouring the liquid preparation into an oil-soluble shaping film and packaging;
(d) putting the packaged oil-soluble shaping film outside a coating machine for water-soluble coating;
(e) and coating the lubricating oil on the outer side of the water-soluble coating.
(f) And packaging the honey glycerine enema.
Example 4
(a) Mixing honey, acetic acid, normal saline, angelica, radix bupleuri and rhizoma atractylodis macrocephalae to prepare a liquid preparation;
(b) preparing an oil-soluble shaping film from the oil-soluble material through a die;
(c) pouring the liquid preparation into an oil-soluble shaping film and packaging;
(d) putting the packaged oil-soluble shaping film outside a coating machine for water-soluble coating;
(e) and coating the lubricating oil on the outer side of the water-soluble coating.
(f) And packaging the honey glycerine enema.
Example 5
(a) Mixing honey, acetic acid, normal saline, scutellaria baicalensis, golden cypress, radix sophorae flavescentis and radix bupleuri to prepare a liquid preparation;
(b) preparing an oil-soluble shaping film from the oil-soluble material through a die;
(c) pouring the liquid preparation into an oil-soluble shaping film and packaging;
(d) putting the packaged oil-soluble shaping film outside a coating machine for water-soluble coating;
(e) and coating the lubricating oil on the outer side of the water-soluble coating.
(f) And packaging the honey glycerine enema.
Example 6
(a) Mixing honey, acetic acid, normal saline, bighead atractylodes rhizome, scutellaria baicalensis, liquorice, angelica and salvia miltiorrhiza to prepare a liquid preparation;
(b) preparing an oil-soluble shaping film from the oil-soluble material through a die;
(c) pouring the liquid preparation into an oil-soluble shaping film and packaging;
(d) putting the packaged oil-soluble shaping film outside a coating machine for water-soluble coating;
(e) and coating the lubricating oil on the outer side of the water-soluble coating.
(f) And packaging the honey glycerine enema.
The honey enema prepared by the implementation can be used only by tearing off the package, and can be conveniently plugged into an intestinal tract due to the lubricating oil on the outer surface, after the honey enema is plugged into the intestinal tract, the water is contained in the intestinal tract, the water-soluble coating layer on the outer layer is gradually dissolved, and after the water-soluble coating layer on the outer layer is dissolved, the oil-soluble film-fixing layer and the external lubricating oil can be used as a base, so that the honey enema is gradually dissolved under the action of the lubricating oil, and the internal liquid preparation flows out; the honey enema adopts soluble materials to package, and can be directly plugged into the intestinal tract during use, so that the honey enema is more convenient to use, does not scratch the body and has safe and effective use effect.
The above description is only a preferred embodiment of the present invention, and is not intended to limit the scope of the present invention, and all modifications and equivalents of the present invention, which are made by the contents of the present specification and the accompanying drawings, or directly/indirectly applied to other related technical fields, are included in the scope of the present invention.

Claims (9)

1. A honey glycerine enema is characterized by comprising:
a soluble coating layer;
the liquid preparation is filled in the coating layer;
the lubricant is coated on the surface of the coating layer;
the liquid preparation consists of honey, acetic acid, physiological saline and auxiliary materials;
the coating layer comprises a soluble shaping film and a water-soluble coating layer coated on the outer surface of the shaping layer; the shaping layer is an oil-soluble shaping film, and the liquid preparation is filled in the inner cavity of the oil-soluble shaping film; the lubricant is coated on the surface of the water-soluble coating layer.
2. A honey enema according to claim 1, wherein the diameter of one end of the oil-soluble shaped film gradually increases towards the other end, and the end of the small diameter end is of a round head structure.
3. A honey enema according to claim 2, wherein the excipient is an active agent.
4. A honey enema according to claim 3, characterized in that: the active agent comprises one or more of Scutellariae radix, cortex Phellodendri, radix Sophorae Flavescentis, and bupleuri radix extract.
5. A honey enema according to claim 3, wherein the active agent comprises one or more of extracts of Atractylodes macrocephala, Scutellaria baicalensis, Glycyrrhiza uralensis, Angelica sinensis, Salvia miltiorrhiza.
6. A honey enema according to any of claims 1 to 5, wherein the lubricant is a lubricating oil.
7. The preparation method of the honey glycerine enema is characterized by comprising the following steps:
(a) mixing honey, acetic acid, physiological saline and auxiliary materials to prepare a liquid preparation;
(b) preparing an oil-soluble shaping film from the oil-soluble material through a die;
(c) pouring the liquid preparation into an oil-soluble shaping film and packaging;
(d) covering the outer surface of the packaged oil-soluble shaping film with a water-soluble coating;
(e) and applying a lubricant to the outside of the water-soluble coating.
8. A method for preparing a honey enema according to claim 7, wherein the step of coating the outer surface of the oil soluble setting film with a water soluble coating is carried out in a coating machine.
9. A method of preparing honey enema according to claim 7, further comprising the step of packaging the honey enema.
CN202010840553.3A 2020-08-20 2020-08-20 Honey enema and preparation method thereof Pending CN111956686A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1224346A (en) * 1996-07-04 1999-07-28 吉水公子 Lubrication assistant and process for preparation of ethyl stearate used therein
CN101385790A (en) * 2007-09-14 2009-03-18 浙江康莱特集团有限公司 Intestine moisturizing soft capsules and preparation method and use thereof
CN110507630A (en) * 2019-09-29 2019-11-29 陈汝霖 A kind of portable cavity sterilization soft capsule

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1224346A (en) * 1996-07-04 1999-07-28 吉水公子 Lubrication assistant and process for preparation of ethyl stearate used therein
CN101385790A (en) * 2007-09-14 2009-03-18 浙江康莱特集团有限公司 Intestine moisturizing soft capsules and preparation method and use thereof
CN110507630A (en) * 2019-09-29 2019-11-29 陈汝霖 A kind of portable cavity sterilization soft capsule

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
吴永钧,等: "蜂蜜灌肠合麻仁滋脾丸治疗老年习惯性便秘47例", 《中国民间疗法》 *
陈德洪,等: "蜂蜜灌肠治疗老年性便秘的效果观察", 《当代护士(学术版)》 *

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Application publication date: 20201120