CN111904480B - Clinical biopsy sampling device that uses of medical oncology - Google Patents

Clinical biopsy sampling device that uses of medical oncology Download PDF

Info

Publication number
CN111904480B
CN111904480B CN202010968862.9A CN202010968862A CN111904480B CN 111904480 B CN111904480 B CN 111904480B CN 202010968862 A CN202010968862 A CN 202010968862A CN 111904480 B CN111904480 B CN 111904480B
Authority
CN
China
Prior art keywords
cutting
needle tube
cavity
hole
cutting blade
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN202010968862.9A
Other languages
Chinese (zh)
Other versions
CN111904480A (en
Inventor
张克
李树勇
李美林
时艳艳
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Qingdao Women and Childrens Hospital
Original Assignee
Qingdao Women and Childrens Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Qingdao Women and Childrens Hospital filed Critical Qingdao Women and Childrens Hospital
Priority to CN202010968862.9A priority Critical patent/CN111904480B/en
Publication of CN111904480A publication Critical patent/CN111904480A/en
Application granted granted Critical
Publication of CN111904480B publication Critical patent/CN111904480B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/0233Pointed or sharp biopsy instruments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/0233Pointed or sharp biopsy instruments
    • A61B10/0266Pointed or sharp biopsy instruments means for severing sample
    • A61B10/0275Pointed or sharp biopsy instruments means for severing sample with sample notch, e.g. on the side of inner stylet
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/0233Pointed or sharp biopsy instruments
    • A61B10/0283Pointed or sharp biopsy instruments with vacuum aspiration, e.g. caused by retractable plunger or by connected syringe

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medical Informatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

The invention relates to the technical field of biopsy sampling, in particular to a biopsy sampling device for clinical use in the medical oncology department, which comprises a needle tube, a mounting block and a pull rod, wherein the right end of the needle tube is fixedly provided with the left side of the mounting block, the left end of the needle tube is fixedly provided with a puncture head for puncturing tissues, and one side of the needle tube, which is close to the puncture head, is provided with a cutting hole with an upward opening; a transition cavity is arranged on the left side in the mounting block, and a connecting block is arranged in the transition cavity; the connecting block right side is provided with the pull rod that extends to the installation piece outside right, the pull rod tip is provided with the piece of gripping, it is provided with the spring to grip between piece and the installation piece. The invention can realize multiple times of sampling on the tissues at the cutting hole in the process of one-time puncture through the cutting hole, the cutting blade and the chute, thereby reducing the operation difficulty of sampling and the sampling time, and further reducing the pain of patients; meanwhile, the tissues of a plurality of samples obtained by continuous sampling cannot slide or be lost, and the effect of continuous sampling is ensured.

Description

Clinical biopsy sampling device that uses of medical oncology
Technical Field
The invention relates to the technical field of biopsy sampling, in particular to a biopsy sampling device for clinical use in the medical oncology department.
Background
Tumors are diseases seriously harming human health and life, the incidence rate gradually rises in recent years, the onset age gradually declines, and early detection, correct diagnosis and timely treatment have important influence on prognosis. With the continuous improvement of examination means and methods, the diagnosis accuracy is gradually improved, but a large part of tumors still have no typical imaging characteristics and are difficult to diagnose. The correct diagnosis requires three combinations of clinical, imaging and pathology. Among them, pathological diagnosis plays a key role in the selection of a treatment regimen. Needle biopsy is the primary way to obtain a pathological diagnosis.
The biopsy puncture sampling device is a special surgical instrument for puncture biopsy, and tumor tissue samples can be extracted by the biopsy puncture sampling device for pathological research. The prior art discloses a biopsy needle set comprising a hollow outer needle and a core extending axially through the outer needle. The puncture needle core can reduce puncture resistance for the needle group when pricking the human body. When the needle group is inserted into the central part of the tumor tissue, the puncture needle core is taken out, the needle plug of the outer needle is connected with a syringe, and the tumor tissue is extracted by the syringe.
The biopsy puncture needle set is easy to diffuse to other parts of a human body along the path of pulling out the outer needle after the tumor tissue sampling cannot be controlled, and the influence is small if the puncture is performed on a good heart tumor; if malignant tumor is punctured, the direct sampling by adopting the biopsy puncture needle set can cause tumor tissues to rapidly spread to other parts of a human body, and great threat is caused to the life of a patient.
Chinese patent (application No. 2015101008202) discloses a biopsy puncture sampling device, comprising: an operating handle provided with a propulsion mechanism; the puncture needle group is connected with the propelling mechanism and extends forwards from the inside to the outside of the operating handle; the protective needle sleeve is detachably arranged at the front end of the operating handle and is axially sleeved on the periphery of the puncture needle group; wherein the puncture needle group is provided with a hollow needle sheath and a puncture needle core which axially penetrates through the needle sheath. This biopsy sampling device that punctures sets up the peripheral protection needle cover of axial suit at puncture needle group through the front end at operating handle, when utilizing this biopsy sampling device that punctures to puncture the biopsy operation, can prevent that puncture needle group from contacting with other healthy positions of human body after extracting tumor tissue to avoid tumor tissue's diffusion, reduce the life threat that leads to the fact the patient. However, the above-mentioned device can only take one sample at a time, and in the case of routine endoscopy, one lesion or one biopsy usually requires a plurality of samples, so that it is necessary to take a plurality of punctures when sampling with the above-mentioned device, which is time-consuming and labor-consuming, and causes more harm to the patient.
Therefore, the biopsy sampling device for clinical use in the medical oncology is designed, the tissue at the cutting hole can be sampled for many times in one puncture process through the cutting hole, the cutting blade and the chute, the operation difficulty of sampling is reduced, and the sampling time is shortened, so that the pain of a patient is reduced; meanwhile, the tissues of a plurality of samples obtained by continuous sampling cannot slide or be lost, and the effect of continuous sampling is ensured.
Disclosure of Invention
In order to make up for the defects of the prior art and solve the problem that the conventional biopsy puncture sampling device cannot realize multiple times of sampling in one puncture process, the invention provides a biopsy sampling device for clinical use in the oncology department.
The technical scheme adopted by the invention for solving the technical problems is as follows: a clinical biopsy sampling device for medical oncology comprises a needle tube, an installation block and a pull rod, wherein the right end of the needle tube is fixedly provided with the left side of the installation block, the left end of the needle tube is fixedly provided with a puncture head for puncturing tissues, and one side of the needle tube, which is close to the puncture head, is provided with a cutting hole with an upward opening; a transition cavity is arranged on the left side in the mounting block, and a connecting block is arranged in the transition cavity; a pull rod extending rightwards to the outside of the mounting block is arranged on the right side of the connecting block, a holding block is arranged at the end part of the pull rod, a spring is arranged between the holding block and the mounting block, and the spring is sleeved outside the pull rod; a cutting blade extending into the needle tube is fixedly arranged on the left side of the connecting block, the cutting blade can move left and right in the needle tube, a cutting edge is arranged at the free end of the cutting blade, and a chute inclined to the right is arranged on the inner side of the cutting blade close to one side of the cutting edge; and one side of the puncture head facing the cutting blade is correspondingly provided with a slot matched with the cutting blade.
When the biopsy puncture sampling device is used, a puncture biopsy operation is performed by using the biopsy puncture sampling device, a puncture head of a needle tube is punctured into a tissue through the mounting block, then the puncture head is pulled to the right to the pull rod, the cutting blade is driven to move to the right through the connecting block, and then the cutting hole is opened; the pull rod is pulled to the right again, due to the arrangement of the inclined grooves, tissue samples entering the needle tube can expand and are attached to the inclined grooves, the inclined grooves can hook the tissue samples, the tissue samples are driven to be far away from the right side of the needle tube of the cutting hole, and when the rod is extruded to the left again, the tissue samples can be separated from the inclined grooves and stay in the right side of the needle tube, so that the cutting blade reciprocates in the needle tube for multiple times, the tissues at the cutting hole are sampled for multiple times in the process of one-time puncture, the operation difficulty of sampling is reduced, the sampling time is shortened, and the pain of a patient is reduced; because the cut tissue samples can be stacked in the right side of the needle tube in sequence, a plurality of samples obtained by continuous sampling can not slide or be lost, and the effect of continuous sampling is ensured; in addition, the cut tissue sample can be far away from the cutting hole, so that the tissue entering from the cutting hole subsequently can not be blocked, the condition that the use requirement is not met due to the fact that the tissue sample is blocked and the subsequently cut tissue is small is avoided, and meanwhile, the cut tissue sample is not contacted with other healthy parts of a human body in the subsequent cutting, so that the diffusion of tumor tissues possibly contained in the tissue sample is avoided, and the life threat to a patient is reduced.
Preferably, the left side of the mounting block is provided with an ultrasonic actuator, and an output end of the ultrasonic actuator extends into the needle tube and is abutted with the upper end face of the cutting blade. The ultrasonic actuator can enable the cutting blade to move rightwards, the puncturing process is accompanied with ultrasonic vibration with specific frequency and amplitude, the resistance borne by the cutting blade in the puncturing process can be reduced, and meanwhile, the cutting blade generates cracks on the cross section of the biopsy tissue through vibration motion, so that the human tissue is very easy to break at the position, and the sampling precision is improved.
Preferably, a negative pressure pipe is coaxially arranged in the needle tube, a plurality of first through holes which are arranged at intervals along the left-right direction are formed in the negative pressure pipe at the position right below the cutting hole, the left end of the negative pressure pipe is fixedly arranged on the puncture head, and the right end of the negative pressure pipe extends into the transition cavity and is communicated with the transition cavity; the installation piece lower extreme is provided with the aspirator, aspirator upper end extends to in the transition chamber and communicates with the transition chamber, be provided with the piston of taking out the pole in the aspirator. Through the pull rod pulling piston, can make the transition chamber produce the negative pressure, because transition chamber and negative pressure pipe intercommunication, consequently also produce the negative pressure in the negative pressure pipe, and then make cutting hole department produce the negative pressure through first through-hole, can enough inhale the needle tubing with the human tissue around the cutting hole in, avoid leading to the less and unsatisfied user demand's of follow-up cutting's tissue condition because of the tissue sample blocks, simultaneously can pass through the negative pressure pipe with blood or tissue liquid that the cutting produced again, the transition chamber is arranged to the aspirator in, avoid blood or tissue liquid to pollute the focus, influence the field of vision, improve the accuracy of follow-up biopsy.
Preferably, the rotating pipe is sleeved outside the negative pressure pipe, a plurality of partition plates extending to the inner wall of the needle tube are arranged on the rotating pipe, the partition plates are arranged along the left and right direction, a cutting cavity is formed by the space between every two adjacent partition plates, and a group of cutting blades are arranged in each cutting cavity; a second through hole matched with the first through hole is formed in the rotary pipe in each cutting cavity; the right end of the needle tube is provided with a rotary plug, the rotary plug is sleeved outside the negative pressure tube, and the rotary plug is correspondingly provided with a jack matched with the cutting blade. The cutting piece is rotated by rotating the holding block, the rotating pipe is driven to rotate by pushing the partition plate through the cutting piece, and the position of the cutting cavity is adjusted, so that the cutting piece in one cutting cavity can rotate one station after being used for realizing single cutting, and the cutting piece in the other cutting cavity is used for realizing secondary cutting sampling, so that different cutting pieces adopted by different puncture depths are realized, the tissue infected on the cutting piece is prevented from contacting other healthy parts of a human body when the puncture sampling of different depths is carried out, the diffusion of tumor tissue possibly contained in the tissue sample is avoided, and the life threat to a patient is reduced; the rotary plug can position and support the cutting piece in an auxiliary mode, and the cutting effect is prevented from being influenced by overlong bending of the cutting piece.
Preferably, be provided with the arc between the adjacent baffle, the arc is located between cutting hole and the rotatory stopper, the arc will cut the cutting chamber on cutting hole right side and separate into the direction chamber of top and the chamber that holds of below, the direction chamber is used for cutting the direction and the auxiliary stay of piece, hold taking in that the chamber is used for cutting back tissue. Through the setting of arc, on the one hand, can be used for the direction and the auxiliary stay of cutting piece through the direction chamber, on the other hand can make the sample tissue after the cutting driven by the chute of cutting piece and the extrusion enters into and holds the intracavity, has consequently avoided sample tissue and the contact of cutting piece medial surface and has increased the condition of the resistance that the cutting piece receives.
Preferably, the negative pressure pipe periphery is provided with a plurality of elastic protrusions, all second through-holes except the top second through-hole of the insertion that elastic protrusion can one-to-one, elastic protrusion can break away from corresponding second through-hole when the pressurized. Because the baffle state in the syringe needle is invisible, consequently realize the location of rotatory pipe under the circumstances that does not influence rotatory pipe rotation through elastic bulge, and then realize when elastic bulge inserts corresponding second through-hole, first through-hole and the second through-hole intercommunication of top, the cutting hole only communicates with the cutting chamber of top simultaneously, avoids the inaccurate problem that leads to influencing cutting piece cutting effect in location.
Preferably, the side walls of the cutting aperture are at least partially surrounded by a sharp knife-edge, and the knife-edge cooperates with the cutting edge of the cutting blade when cutting tissue. The human tissue can be easily broken at this point by the knife-edge, and the sample tissue can be easily cut off when it cooperates with the cutting edge of the cutting blade, thereby improving the sampling precision.
The invention has the following beneficial effects:
1. according to the biopsy sampling device for clinical oncology, disclosed by the invention, multiple times of sampling of tissues at the cutting hole can be realized in one puncture process through the cutting hole, the cutting blade and the chute, the operation difficulty of sampling is reduced, and the sampling time is reduced, so that the pain of a patient is reduced; meanwhile, the tissues of a plurality of samples obtained by continuous sampling cannot slide or be lost, and the effect of continuous sampling is ensured.
2. According to the biopsy sampling device for clinical use in the medical oncology department, the different cutting sheets used for different puncture depths are realized through the partition plate, so that the tissues stained on the cutting sheets are prevented from contacting other healthy parts of a human body when puncture sampling is carried out at different depths, the diffusion of tumor tissues possibly contained in tissue samples is avoided, and the life threat to patients is reduced.
Drawings
The invention will be further explained with reference to the drawings.
FIG. 1 is a perspective view of the present invention;
FIG. 2 is a cross-sectional view of the present invention;
FIG. 3 is an enlarged view of a portion of FIG. 2 at A;
FIG. 4 is a sectional view at the separator in the present invention;
FIG. 5 is a schematic view of the structure at the separator in the present invention;
FIG. 6 is an enlarged view of a portion of FIG. 2 at B;
FIG. 7 is a cross-sectional view of a rotating plug according to the present invention;
in the figure:
1. a needle tube; 11. cutting the hole; 12. a needle head; 13. a slot; 14. a rotating plug; 15. a jack; 2. mounting blocks; 21. an ultrasonic actuator; 22. a transition chamber; 3. an aspirator; 31. a piston; 32. drawing a rod; 4. a pull rod; 41. a spring; 42. a connecting disc; 5. a negative pressure tube; 51. a first through hole; 52. an elastic bulge; 6. rotating the tube; 61. a second through hole; 7. a partition plate; 8. an arc-shaped plate; 9. cutting the slices; 91. a chute.
Detailed Description
In order to make the technical means, the creation characteristics, the achievement purposes and the effects of the invention easy to understand, the invention is further described with the specific embodiments.
As shown in fig. 1 to 7, a biopsy sampling device for clinical use in medical oncology comprises a needle tube 1, a mounting block 2 and a pull rod 4, wherein the right end of the needle tube 1 is fixedly provided with the left side of the mounting block 2, the left end of the needle tube 1 is fixedly provided with a puncture head for puncturing tissues, and one side of the needle tube 1, which is close to the puncture head, is provided with a cutting hole 11 with an upward opening; a transition cavity 22 is arranged on the left side in the mounting block 2, and a connecting block is arranged in the transition cavity 22; a pull rod 4 extending rightwards to the outside of the mounting block 2 is arranged on the right side of the connecting block, a holding block is arranged at the end part of the pull rod 4, a spring 41 is arranged between the holding block and the mounting block 2, and the spring 41 is sleeved outside the pull rod 4; a cutting blade 9 extending into the needle tube 1 is fixedly arranged on the left side of the connecting block, the cutting blade 9 can move left and right in the needle tube 1, a cutting edge is arranged at the free end of the cutting blade 9, and a chute 91 inclined to the right is arranged on the inner side of the cutting blade 9 close to one side of the cutting edge; the puncture head is correspondingly provided with a slot 13 matched with the cutting blade 9 towards one side of the cutting blade 9.
When the biopsy puncture sampling device is used, a puncture head of a needle tube 1 is punctured into a tissue through the mounting block 2, then the puncture head is pulled to the right to the pull rod 4, the cutting blade 9 is driven to move to the right through the connecting block, and then the cutting hole 11 is opened, at the moment, part of the tissue enters the needle tube 1 from the cutting hole 11 due to certain elasticity of the tissue, and then the cutting blade 9 is inserted into the slot 13 by extruding the rod to the left, the cutting edge of the cutting blade 9 can cut the tissue entering the needle tube 1 in the process, and single biopsy sampling of single puncture is realized; the pull rod 4 is pulled rightwards again, due to the arrangement of the inclined grooves 91, the tissue sample entering the needle tube 1 can expand and be attached to the inclined grooves 91, the inclined grooves 91 can hook the tissue sample and drive the tissue sample to be far away from the right side of the needle tube 1 of the cutting hole 11, and when the rod is extruded leftwards again, the tissue sample can be separated from the inclined grooves 91 and stays in the right side of the needle tube 1, so that the cutting blade 9 reciprocates for multiple times in the needle tube 1, multiple sampling of the tissue at the cutting hole 11 is realized in one puncture process, the operation difficulty of sampling is reduced, the sampling time is reduced, and the pain of a patient is reduced; because the cut tissue samples can be stacked in the right side of the needle tube 1 in sequence, a plurality of samples obtained by continuous sampling can not slide or be lost, and the effect of continuous sampling is ensured; in addition, the cut tissue sample can be far away from the cutting hole 11, so that the tissue entering from the cutting hole 11 subsequently can not be blocked, the condition that the tissue cut subsequently is small and cannot meet the use requirement due to the blocking of the tissue sample is avoided, and meanwhile, the cut tissue sample can not be contacted with other healthy parts of a human body in the subsequent cutting, so that the diffusion of tumor tissues possibly contained in the tissue sample is avoided, and the life threat to a patient is reduced.
As an embodiment of the present invention, an ultrasonic actuator 21 is provided on the left side of the mounting block 2, and the output end of the ultrasonic actuator 21 extends into the needle tube 1 and is abutted against the upper end face of the cutting blade 9. The ultrasonic actuator 21 can cause the cutting blade 9 to move rightwards, the puncturing process is accompanied with ultrasonic vibration with specific frequency and amplitude, the resistance borne by the cutting blade 9 in the puncturing process can be reduced, and meanwhile, the vibration motion enables the cutting edge to generate cracks on the cross section of the biopsy tissue, so that the human tissue is very easy to break at the position, and the sampling precision is improved.
As an embodiment of the present invention, a negative pressure tube 5 is coaxially arranged in the needle tube 1, a plurality of first through holes 51 arranged at intervals in the left-right direction are arranged at the position of the negative pressure tube 5 right below the cutting hole 11, the left end of the negative pressure tube 5 is fixedly arranged on the puncture head, and the right end of the negative pressure tube 5 extends into the transition cavity 22 and is communicated with the transition cavity 22; the lower end of the mounting block 2 is provided with a suction device 3, the upper end of the suction device 3 extends into the transition cavity 22 and is communicated with the transition cavity 22, and a piston 31 with a suction rod 32 is arranged in the suction device 3. Pulling piston 31 through the pull rod 32, can make transition chamber 22 produce the negative pressure, because transition chamber 22 and negative pressure pipe 5 intercommunication, consequently also produce the negative pressure in the negative pressure pipe 5, and then make cutting hole 11 department produce the negative pressure through first through-hole 51, can enough inhale the human tissue around cutting hole 11 in needle tubing 1, avoid leading to the less unsatisfied user demand's of the tissue of follow-up cutting the circumstances because of tissue sample blocks, can arrange the aspirator 3 through negative pressure pipe 5, transition chamber 22 with the blood or the tissue liquid that the cutting produced simultaneously again, avoid blood or tissue liquid to pollute the focus, influence the field of vision, improve the accuracy of follow-up biopsy.
As an embodiment of the invention, a rotating tube 6 is sleeved outside a negative pressure tube 5, a plurality of partition plates 7 extending to the inner wall of a needle tube 1 are arranged on the rotating tube 6, the partition plates 7 are arranged along the left and right direction, the space between every two adjacent partition plates 7 forms a cutting cavity, and a group of cutting blades 9 are arranged in each cutting cavity; a second through hole 61 matched with the first through hole 51 is formed in the rotary pipe 6 in each cutting cavity; the right end of the needle tube 1 is provided with a rotary plug 14, the rotary plug 14 is sleeved outside the negative pressure tube 5, and the rotary plug 14 is correspondingly provided with a jack 15 matched with the cutting blade 9. The cutting piece 9 is rotated by rotating the holding block, the rotating pipe 6 is driven to rotate by pushing the partition plate 7 through the cutting piece 9, and the adjustment of the position of the cutting cavity is completed, so that the cutting piece 9 in one cutting cavity can be used for realizing one-time cutting and then rotating one station, and the cutting piece 9 in the other cutting cavity is used for realizing the second-time cutting and sampling, so that the cutting pieces 9 adopted by different puncture depths are different, the tissue stained on the cutting piece 9 is prevented from contacting other healthy parts of a human body when the puncture sampling at different depths is carried out, the diffusion of tumor tissue possibly contained in a tissue sample is avoided, and the life threat to a patient is reduced; the rotary plug 14 can position and support the cutting blade 9, and the cutting effect of the cutting blade 9 is prevented from being influenced by overlong bending.
As an embodiment of the present invention, an arc plate 8 is disposed between adjacent partition plates 7, the arc plate 8 is located between the cutting hole 11 and the rotary plug 14, the arc plate 8 divides the cutting cavity on the right side of the cutting hole 11 into an upper guide cavity and a lower accommodating cavity, the guide cavity is used for guiding and supporting the cutting blade 9, and the accommodating cavity is used for accommodating the cut tissue. Through the setting of arc 8, on the one hand, can be used for cutting piece 9's direction and auxiliary stay through the direction chamber, on the other hand can make the sample tissue after the cutting driven and the extrusion enters into by cutting piece 9's chute 91 and holds the intracavity, has consequently avoided sample tissue and cutting piece 9 medial surface contact and has increased the condition of the resistance that cutting piece 9 received.
In one embodiment of the present invention, the negative pressure pipe 5 is provided with a plurality of elastic protrusions 52 on the outer circumference thereof, the elastic protrusions 52 are correspondingly inserted into all the second through holes 61 except the uppermost second through hole 61, and the elastic protrusions 52 are disengaged from the corresponding second through holes 61 when being pressed. Because baffle 7 state in the needle tubing 1 is invisible, consequently realize the location of rotatory pipe 6 under the circumstances that does not influence rotatory pipe 6 rotation through elastic bulge 52, and then realize when elastic bulge 52 inserts corresponding second through-hole 61, first through-hole 51 communicates with the second through-hole 61 of the top, and cutting hole 11 only communicates with the cutting chamber of the top simultaneously, avoids the inaccurate problem that leads to influencing cutting piece 9 cutting effect of location.
As an embodiment of the invention, the side walls of the cutting hole 11 are at least partially surrounded by a sharp knife-edge and the knife-edge cooperates with the cutting edge of the cutting blade 9 when cutting tissue. The human tissue can here be broken very easily by the knife-edge, and the sample tissue can be cut off easily when it cooperates with the cutting edge of the cutting blade 9, thus improving the sampling accuracy.
When the biopsy puncture sampling device is used, a puncture biopsy operation is carried out by utilizing the biopsy puncture sampling device, a puncture head of a needle tube 1 is punctured into a tissue through the mounting block 2, then the puncture head is pulled to the right to the pull rod 4, the cutting blade is driven to move to the right through the connecting block, and then the cutting hole 11 is opened, at the moment, part of the tissue has certain elasticity, can enter the needle tube 1 from the cutting hole 11, then the cutting blade is inserted into the slot 13 by extruding the rod to the left, the cutting blade of the cutting blade can enter the tissue in the needle tube 1 through a cutter in the process, and single puncture biopsy sampling is realized; the pull rod 4 is pulled rightwards again, due to the arrangement of the inclined grooves, the tissue sample entering the needle tube 1 can expand and be attached to the inclined grooves, the inclined grooves can hook the tissue sample and drive the tissue sample to be far away from the right side of the needle tube 1 of the cutting hole 11, and when the rod is extruded leftwards again, the tissue sample can be separated from the inclined grooves and stays in the right side of the needle tube 1, so that the cutting blade reciprocates for a plurality of times in the needle tube 1, the tissue at the position of the cutting hole 11 is sampled for a plurality of times in the process of one-time puncture, the operation difficulty of sampling is reduced, the sampling time is shortened, and the pain of a patient is reduced; because the cut tissue samples can be stacked in the right side of the needle tube 1 in sequence, a plurality of samples obtained by continuous sampling can not slide or be lost, and the effect of continuous sampling is ensured; in addition, the cut tissue sample can be far away from the cutting hole 11, so that the tissue entering from the cutting hole 11 subsequently can not be blocked, the condition that the use requirement is not met due to the small subsequently cut tissue caused by the blocking of the tissue sample is avoided, and meanwhile, the cut tissue sample can not be contacted with other healthy parts of a human body in the subsequent cutting, so that the diffusion of tumor tissue possibly contained in the tissue sample is avoided, and the life threat to a patient is reduced; the ultrasonic actuator 21 can cause the cutting blade to move rightwards, the puncturing process is accompanied with ultrasonic vibration with specific frequency and amplitude, the resistance borne by the cutting blade in the puncturing process can be reduced, and meanwhile, the cutting blade generates cracks on the cross section of the biopsy tissue due to the vibration motion, so that the human tissue is very easy to break at the position, and the sampling precision is improved; the piston 31 is pulled through the drawing rod 32, so that negative pressure can be generated in the transition cavity 22, the transition cavity 22 is communicated with the negative pressure pipe 5, negative pressure is generated in the negative pressure pipe 5, and then negative pressure is generated at the cutting hole 11 through the first through hole, so that human tissues around the cutting hole 11 can be sucked into the needle tube 1, the condition that the use requirement is not met due to small tissues for subsequent cutting caused by the obstruction of a tissue sample is avoided, blood or tissue fluid generated by cutting can be discharged into the aspirator 3 through the negative pressure pipe 5 and the transition cavity 22, the focus is prevented from being polluted by the blood or the tissue fluid, the visual field is prevented from being influenced, and the accuracy of subsequent biopsy is improved; the cutting piece is rotated by rotating the holding block, the rotating pipe is driven to rotate by pushing the partition plate through the cutting piece, and the position of the cutting cavity is adjusted, so that the cutting piece in one cutting cavity can rotate one station after being used for realizing single cutting, and the cutting piece in the other cutting cavity is used for realizing secondary cutting sampling, so that different cutting pieces adopted by different puncture depths are realized, the tissue infected on the cutting piece is prevented from contacting other healthy parts of a human body when the puncture sampling of different depths is carried out, the diffusion of tumor tissue possibly contained in the tissue sample is avoided, and the life threat to a patient is reduced; the rotary plug 14 can position and support the cutting piece in an auxiliary way, so that the cutting effect is prevented from being influenced by overlong bending of the cutting piece; through the arrangement of the arc-shaped plate, on one hand, the guide cavity can be used for guiding and assisting in supporting the cutting blade, and on the other hand, the cut sample tissue can be driven by the chute of the cutting blade and extruded into the accommodating cavity, so that the situation that the sample tissue is contacted with the inner side surface of the cutting blade to increase the resistance of the cutting blade is avoided; because the state of the partition board in the needle tube 1 is invisible, the rotary tube is positioned under the condition that the rotation of the rotary tube is not influenced through the elastic bulge, so that when the elastic bulge is inserted into the corresponding second through hole, the first through hole is communicated with the uppermost second through hole, and meanwhile, the cutting hole 11 is only communicated with the uppermost cutting cavity, thereby avoiding the problem that the cutting effect of a cutting piece is influenced due to inaccurate positioning; the human tissue can be very easily broken at this point by the knife-edge, and the sample tissue can be easily cut off when it cooperates with the cutting edge of the cutting blade, thereby improving the sampling accuracy.
The foregoing illustrates and describes the principles, general features, and advantages of the present invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims (4)

1. A biopsy sampling device for clinical use in medical oncology is characterized by comprising a needle tube (1), a mounting block (2) and a pull rod (4), wherein the right end of the needle tube (1) is fixedly provided with the left side of the mounting block (2), the left end of the needle tube (1) is fixedly provided with a puncture head for puncturing tissues, and one side of the needle tube (1) close to the puncture head is provided with a cutting hole (11) with an upward opening; a transition cavity (22) is arranged on the left side in the mounting block (2), and a connecting block is arranged in the transition cavity (22); a pull rod (4) extending rightwards to the outside of the mounting block (2) is arranged on the right side of the connecting block, a holding block is arranged at the end part of the pull rod (4), a spring (41) is arranged between the holding block and the mounting block (2), and the spring (41) is sleeved outside the pull rod (4); a cutting blade (9) extending into the needle tube (1) is fixedly arranged on the left side of the connecting block, the cutting blade (9) can move left and right in the needle tube (1), a cutting edge is arranged at the free end of the cutting blade, and a chute (91) which is inclined to the right is arranged on the inner side of the cutting blade (9) close to one side of the cutting edge; a slot (13) matched with the cutting blade (9) is correspondingly arranged on one side of the puncture head facing the cutting blade (9);
an ultrasonic actuator (21) is arranged on the left side of the mounting block (2), and the output end of the ultrasonic actuator (21) extends into the needle tube (1) and is abutted against the upper end face of the cutting blade (9);
a negative pressure pipe (5) is coaxially arranged in the needle tube (1), a plurality of first through holes (51) which are arranged at intervals along the left-right direction are formed in the position, located right below the cutting hole (11), of the negative pressure pipe (5), the left end of the negative pressure pipe (5) is fixedly arranged on the puncture head, and the right end of the negative pressure pipe (5) extends into the transition cavity (22) and is communicated with the transition cavity (22); the lower end of the mounting block (2) is provided with a suction device (3), the upper end of the suction device (3) extends into the transition cavity (22) and is communicated with the transition cavity (22), and a piston (31) with a suction rod (32) is arranged in the suction device (3);
a rotating pipe (6) is sleeved outside the negative pressure pipe (5), a plurality of partition plates (7) extending to the inner wall of the needle tube (1) are arranged on the rotating pipe (6), the partition plates (7) are arranged along the left and right directions, a cutting cavity is formed by the space between every two adjacent partition plates (7), and a group of cutting pieces (9) are arranged in each cutting cavity; a second through hole (61) matched with the first through hole (51) is formed in the rotary pipe (6) in each cutting cavity; the needle tube (1) right-hand member is provided with rotatory stopper (14), rotatory stopper (14) suit is outside negative pressure pipe (5), correspond on rotatory stopper (14) and be provided with jack (15) that match with cutting piece (9).
2. The biopsy sampling device for clinical use in oncology department according to claim 1, characterized in that an arc-shaped plate (8) is arranged between adjacent partition plates (7), the arc-shaped plate (8) is located between the cutting hole (11) and the rotating plug (14), the cutting cavity on the right side of the cutting hole (11) is divided into an upper guide cavity and a lower containing cavity by the arc-shaped plate (8), the guide cavity is used for guiding and assisting the support of the cutting blade (9), and the containing cavity is used for containing cut tissues.
3. The biopsy sampling device for clinical use in oncology department according to claim 2, characterized in that the negative pressure tube (5) is provided with a plurality of elastic protrusions (52) at the periphery, the elastic protrusions (52) can be inserted into all the second through holes (61) except the uppermost second through hole (61) in a one-to-one correspondence manner, and the elastic protrusions (52) can be separated from the corresponding second through holes (61) when being pressed.
4. A clinical biopsy sampling device according to claim 3, wherein the side walls of the cutting hole (11) are at least partly surrounded by a sharp knife-edge and the knife-edge cooperates with the cutting edge of the cutting blade (9) when cutting tissue.
CN202010968862.9A 2020-09-15 2020-09-15 Clinical biopsy sampling device that uses of medical oncology Active CN111904480B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010968862.9A CN111904480B (en) 2020-09-15 2020-09-15 Clinical biopsy sampling device that uses of medical oncology

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202010968862.9A CN111904480B (en) 2020-09-15 2020-09-15 Clinical biopsy sampling device that uses of medical oncology

Publications (2)

Publication Number Publication Date
CN111904480A CN111904480A (en) 2020-11-10
CN111904480B true CN111904480B (en) 2022-09-16

Family

ID=73267970

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202010968862.9A Active CN111904480B (en) 2020-09-15 2020-09-15 Clinical biopsy sampling device that uses of medical oncology

Country Status (1)

Country Link
CN (1) CN111904480B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112690835A (en) * 2020-12-23 2021-04-23 重庆市公共卫生医疗救治中心 AIDS lung puncture biopsy device and use method thereof
CN113017776B (en) * 2020-12-24 2022-05-17 中国人民解放军总医院第三医学中心 Superficial tumor closed resection device and use method thereof
CN113100839A (en) * 2021-04-22 2021-07-13 莒县中医医院 Lung tissue extraction element based on medical science inspection is used
CN113440181B (en) * 2021-07-06 2022-07-12 中南大学湘雅医院 Biological tissue biopsy sampling device based on endoscopic system
CN114366179A (en) * 2022-02-14 2022-04-19 南京华银医学检验所有限公司 Liver tissue biopsy device and use method thereof
CN115462842A (en) * 2022-09-30 2022-12-13 哈尔滨理工大学 Rotary-cut mammary gland biopsy device with water conservancy diversion function
CN116509535B (en) * 2023-03-14 2024-01-23 武汉金柏威光电技术有限公司 Medical high-frequency electrotome
CN116296687A (en) * 2023-03-31 2023-06-23 中国中医科学院医学实验中心 Tissue sample preparation device and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101032419A (en) * 2006-03-07 2007-09-12 伊西康内外科公司 Device for minimally invasive internal tissue removal
WO2018161067A1 (en) * 2017-03-03 2018-09-07 Arizona Board Of Regents On Behalf Of The University Of Arizona Biopsy system for enhanced tissue harvesting

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030204199A1 (en) * 2002-04-30 2003-10-30 Novak Theodore A. D. Device and method for ultrasonic tissue excision with tissue selectivity
US6981949B2 (en) * 2002-06-06 2006-01-03 Ethicon Endo-Surgery, Inc. Perimeter cut biopsy probe
US20050165329A1 (en) * 2004-01-22 2005-07-28 Reflux Corporation Multiple biopsy collection device
US20070142852A1 (en) * 2005-12-21 2007-06-21 Manoa Medical, Inc., A Delaware Corporation Tissue cutting device
US20080300506A1 (en) * 2007-05-29 2008-12-04 Boston Scientific Scimed, Inc. Biopsy device with multiple cutters
TR200802738A2 (en) * 2008-04-18 2010-03-22 Eren Orhan A practical and safe needle biopsy device.

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101032419A (en) * 2006-03-07 2007-09-12 伊西康内外科公司 Device for minimally invasive internal tissue removal
WO2018161067A1 (en) * 2017-03-03 2018-09-07 Arizona Board Of Regents On Behalf Of The University Of Arizona Biopsy system for enhanced tissue harvesting

Also Published As

Publication number Publication date
CN111904480A (en) 2020-11-10

Similar Documents

Publication Publication Date Title
CN111904480B (en) Clinical biopsy sampling device that uses of medical oncology
JP6737829B2 (en) Biopsy device
JP4781815B2 (en) Method of manufacturing a needle assembly for use with a biopsy device
ES2347483T3 (en) BIOPSY DEVICE.
US9301737B2 (en) Needle tip for biopsy device
JP2005288175A (en) Marker device and method for arranging marker using surgical biopsy device
US10363019B2 (en) Biopsy needle, biopsy needle assembly, and methods for biopsy
RU50799U1 (en) DEVICE FOR PUNCH BIOPSY
CN104644225A (en) Biopsy puncture sampling device
JP2000232983A (en) Tissue sampling device
CN111345856A (en) Disposable biopsy needle
CN112315557A (en) Puncture needle with aligned inner and outer needle bevels
WO2014091502A1 (en) Devices and methods for biopsy
JP2011030913A (en) Tissue sampling implement for endoscope
CN209734028U (en) Biopsy sampling and collecting device for clinical medicine
CN211022797U (en) Integrated puncture biopsy needle
WO2021151061A2 (en) Bone marrow aspiration and biopsy device
CN112545577A (en) Biopsy device for windowing bone tumor or bone disease
CN204520785U (en) A kind of Biopsy sampler
CN213697105U (en) Bone marrow puncture biopsy integrated needle
CN213465119U (en) Centrum pathology biopsy sampling device
CN220778374U (en) Tissue sampler
CN214511218U (en) Disposable biopsy spoon
CN217390851U (en) Double-electrode electrocoagulation biopsy needle and double-electrode electrocoagulation biopsy system
CN219699985U (en) Biopsy needle structure

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant