CN111839522A - 计算机辅助制作制备生物填充材料的方法 - Google Patents

计算机辅助制作制备生物填充材料的方法 Download PDF

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CN111839522A
CN111839522A CN202010122223.0A CN202010122223A CN111839522A CN 111839522 A CN111839522 A CN 111839522A CN 202010122223 A CN202010122223 A CN 202010122223A CN 111839522 A CN111839522 A CN 111839522A
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computer
filling material
biological filling
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陈蕾
祁少海
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First Affiliated Hospital of Sun Yat Sen University
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/107—Measuring physical dimensions, e.g. size of the entire body or parts thereof
    • A61B5/1073—Measuring volume, e.g. of limbs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/10—Computer-aided planning, simulation or modelling of surgical operations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/44—Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
    • A61B5/441—Skin evaluation, e.g. for skin disorder diagnosis
    • A61B5/445—Evaluating skin irritation or skin trauma, e.g. rash, eczema, wound, bed sore
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/0059—Cosmetic or alloplastic implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/10—Computer-aided planning, simulation or modelling of surgical operations
    • A61B2034/101—Computer-aided simulation of surgical operations
    • A61B2034/105—Modelling of the patient, e.g. for ligaments or bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2240/00—Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2240/001—Designing or manufacturing processes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Veterinary Medicine (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Measuring And Recording Apparatus For Diagnosis (AREA)

Abstract

本实验设计主要针对人体对称部位烧伤后所致局部缺损，通过三维扫描获得创面数据，经计算机处理后重建缺损组织的三维立体结构，经过再处理获得烧伤片面数据，根据数据生产制作与创面契合的生物填充材料，以期达到接近原状态的修复。

Description

计算机辅助制作制备生物填充材料的方法
技术领域
本发明涉及医疗测量领域，特别是一种计算机辅助烧伤创面的测量方法。
背景技术
整形创伤外科在关注严重毁损组织的恢复之外，越来越注重组织修复后的美的平衡和对称，让创伤后的幸存者真正回到正常的社会生活当中，这需要明确先天或者后天造成的畸形或缺损组织的解剖层次、预制修复组织的精确单位、感觉和运动的良好重建，以及适当的化装修饰。
多年来，美容整形修复手术主要凭借经验来估计，以至于经常发生手术效果欠佳的担忧。目前医学界中外伤、烧伤、肿瘤术后局部组织畸形和缺损需求修复的患者日渐增多，高难度的先天畸形和组织缺损的矫正修复更需要提供术前设计、术后显示和快速量化的矫正模块—以避免医生的盲目性操作、缩短手术时间。在患者创面手动测量，存在人为因素和测量面不平整等操作困难，造成测量费时费力结果却不精确的结果。为了解决这些切实的问题，确立科学的量化指标，采集手术前后的患者创面数据，以指导临床应用，是迫在眉睫的事情。
发明内容
计算机图像技术的出现，为上面问题的解决带来了希望，而三维测量的引入是形态学精确测量分析的另外一个突破，它可以时实的完成测量物各个角度的测量和分析，获得的数据具有很高的精确度和可重复性。三维图像的出现，令术者和受术者的术前“完美”模拟成为可能。准确的三维重建图像能够在三维层面上加深人们对组织形态结构的了解，从而能准确、完整地显示组织比邻关系以及立体形态，并且可以根据时间轴量化衰老。如此，仿真的术前设计、真实的术后效果评估，都将随着三维扫描仪和快速成型***的出现，一步一步的走向完善。让临床医生在诊断和治疗上得到一定的帮助。
本实验设计主要针对人体对称部位烧伤后所致局部缺损，通过三维扫描获得创面数据，经计算机处理后重建缺损组织的三维立体结构，经过再处理获得烧伤片面数据，根据数据生产制作与创面契合的生物填充材料，以期达到接近原状态的修复。
具体步骤如下：
步骤1、正常组织结构的测量与分析，将扫描(OBJ格式)数据导入Geomagic studio软件，见图1；
步骤2、缺陷的测量及计算机辅助轮廓重建，选择需要的面片数据，并将其他的无关数据删除，见图2；
步骤3、辅助制造，平滑面片边界，并根据需求增厚见图3；
步骤4、组织生物力学分析结合，将增厚后的实体数据保存为STL格式或OBJ格式。再将该数据导入Materialise Magics软件，见图4-5。
附图说明
图1：将扫描(OBJ格式)数据导入Geomagic studio软件；
图2：选择需要的面片数据，并将其他的无关数据删除；
图3：平滑面片边界，并根据需求增厚；
图4：将增厚后的实体数据保存为STL格式或OBJ格式，再将该数据导入Materialise Magics软件
图5：成品
从上所述，本发明的计算机辅助烧伤创面测量方法，可大幅提高烧伤创面的测量准确性，相应提高了诊断与治疗的准确性，增强治疗效率，同时还具有降低因为医疗失误所导致的治疗、提高治疗质量等诸多优点。

Claims (1)

1.一种生物填充材料的制备方法：其特征在于：
步骤1、正常组织结构的测量与分析，将扫描(OBJ格式)数据导入Geomagic studio软件；
步骤2、缺陷的测量及计算机辅助轮廓重建，选择需要的面片数据，并将其他的无关数据删除；
步骤3、辅助制造，平滑面片边界，并根据需求增厚；
步骤4、组织生物力学分析结合，将增厚后的实体数据保存为STL格式或OBJ格式。再将该数据导入Materialise Magics软件。
CN202010122223.0A 2020-02-27 2020-02-27 计算机辅助制作制备生物填充材料的方法 Pending CN111839522A (zh)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101019785A (zh) * 2007-03-06 2007-08-22 赵亚群 颅骨补片及其制备方法
CN102169519A (zh) * 2011-02-21 2011-08-31 中国人民解放军第四军医大学 一种腭裂牙槽骨塑形矫治器数字化方法
CN103006364A (zh) * 2012-12-31 2013-04-03 中国人民解放军第四军医大学 一种唇腭裂外鼻矫治器数字化制备方法
CN103919631A (zh) * 2014-04-28 2014-07-16 四川大学 一种颌骨缺损个性化修复体的制备方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101019785A (zh) * 2007-03-06 2007-08-22 赵亚群 颅骨补片及其制备方法
CN102169519A (zh) * 2011-02-21 2011-08-31 中国人民解放军第四军医大学 一种腭裂牙槽骨塑形矫治器数字化方法
CN103006364A (zh) * 2012-12-31 2013-04-03 中国人民解放军第四军医大学 一种唇腭裂外鼻矫治器数字化制备方法
CN103919631A (zh) * 2014-04-28 2014-07-16 四川大学 一种颌骨缺损个性化修复体的制备方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
潘景光等: "睁眼数字化面模在眶缺损仿真修复中的应用", 《实用口腔医学杂志》 *
焦婷等: "计算机辅助设计颌面缺损修复技术的开发应用研究", 《中华口腔医学杂志》 *

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Application publication date: 20201030