CN111812043A - Mobile device with hemoglobin detection function - Google Patents

Mobile device with hemoglobin detection function Download PDF

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CN111812043A
CN111812043A CN201910286917.5A CN201910286917A CN111812043A CN 111812043 A CN111812043 A CN 111812043A CN 201910286917 A CN201910286917 A CN 201910286917A CN 111812043 A CN111812043 A CN 111812043A
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intensity signal
light
wavelength
processing unit
intensity
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CN111812043B (en
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颜硕廷
苏冠暐
王怡骅
张振忠
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Rui Ai Biomedical Co ltd
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Rui Ai Biomedical Co ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation

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  • Health & Medical Sciences (AREA)
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  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

The invention relates to a mobile device with a heme detection function, which comprises a processing unit and a first light source for generating a first light beam, wherein a light sensing module receives a second light beam generated after the first light beam passes through a solution to be detected and generates first to fourth light intensity signals according to the second light beam; the processing unit judges whether the spectral distribution of the second light beam accords with a target spectrum according to the first light intensity signal, the fourth light intensity signal and the fourth light intensity signal, if so, positive result information is generated, otherwise, negative result information is generated, and the target spectrum is the absorption spectrum of the blood solution; the device of the invention has the function of quickly and accurately detecting the blood of the excrement solution, does not need to collect a sample and use a chemical reagent, and ensures that a user can detect at any time to obtain self health information.

Description

Mobile device with hemoglobin detection function
Technical Field
The present invention relates to a mobile device, and more particularly, to a mobile device with hemoglobin detection function.
Background
Hemoglobin exists in blood of blood vessels of human beings and most animals, and when various diseases such as inflammation, cancer cell growth, ulcer and the like occur in internal tissues of human bodies, due to the exudation of blood caused by tissue injury, the hemoglobin in the blood appears in secretions such as excrement, saliva, nasal discharge and the like which are externally discharged by human bodies. Therefore, detecting hemoglobin in the multiple secretions is an important indicator for determining whether a lesion occurs in the body. For example, fecal occult blood test for judging colorectal cancer, urinary occult blood test for judging bladder cancer or kidney cancer, expectoration occult blood test for judging bronchitis or lung tumor, and the like.
The colorectal cancer is the first cancer of the taiwan for eleven years, and in the united states, the incidence of colorectal cancer accounts for 8 percent of the incidence of the total cancer, the incidence is the fourth and the mortality is the second. In China, the number of colorectal cancer diseases accounts for 18.6% of the world, the number of colorectal cancer deaths accounts for 20.1% of the world, and the two are the first in the world. An important index for determining colorectal cancer is fecal occult blood detection, that is, when fecal remains contain blood or hemoglobin, it means that colorectal cancer or early stage lesion may have occurred. In the current method, the common detection method is immunoassay occult blood detection, in which a human subject must collect a stool sample by himself/herself, and send back or send to a hospital for medical examination by himself/herself. However, this method is inconvenient because of the long waiting time, and generally people do not have to perform a related health check at most once a year, the detection period is long, and the related detection information cannot be obtained in time when symptoms appear. In addition, when a fecal specimen is collected, because occult blood is not uniformly distributed in the feces, a detection result may be false negative because a part of the feces containing the occult blood is not collected in the test process, that is, the detection result is judged to be negative, but lesions such as tumors or polyps actually appear; moreover, since the tumor or polyp itself usually bleeds intermittently, but does not bleed continuously, if the tumor or polyp does not bleed on the day of or before the collection of the stool sample, the result of the test is also false negative, and the reliability of the test result is lowered.
IN both THE publications US 8,802,442B2 (APPATUS AND METHOD FOR THE REMOTE SENSING OFBLOOD IN HUMAN FECES AND URINE) AND CN104254621A (APPARATUS AND METHOD FOR telemetering blood IN HUMAN FECES AND URINE), it is necessary to add a fluorescent agent or an oxidizing agent to THE toilet bowl, AND irradiate THE object to be tested IN THE toilet bowl with excitation light to determine whether fluorescence is generated. Therefore, the user must prepare the chemical agent consumables, resulting in inconvenience in use.
In US7223604B1 (Methods and kits for the detection of erythrocytes), fluorescence detection is also used to determine whether or not an analyte contains occult blood, and before the fluorescence detection, a reaction solution containing a strong reducing agent with various compounds must be added to the analyte, if the skin of a person is in contact with the reaction solution, there is a risk of burning. The method and the device have a plurality of procedures before actual detection and have high danger, so the method and the device are not suitable for home operation of general untrained users.
In JP 199833979 (fecal component testing device), the user must perform a stool sampling procedure, add extra diluent and perform a washing procedure, and also need to add additional medicinal liquid and the operation procedure is complicated, which results in inconvenience in use.
As can be seen from the above description, some of the methods for detecting occult blood in secretion in the prior art need to operate a feces collection procedure, or need to add various reagents, fluorescent agents, reagents, and other chemicals, which are complicated in procedure and inconvenient to operate, and are not suitable for general users to operate by themselves for self-health management, so the methods for detecting occult blood in secretion in the prior art need to be further improved.
Disclosure of Invention
In view of the complicated procedure and long detection period of the secretion occult blood measuring method in the prior art, or the pollution or contact danger caused by the addition of chemical reagents, the invention provides a mobile device with a hemoglobin detection function. The mobile device with the heme detection function comprises a first light source, a processing unit and a light sensing module. The first light source generates a first light beam, the light sensing module is electrically connected with the processing unit and used for receiving a second light beam generated after the first light beam passes through a solution to be tested and is reflected, and light intensity information is generated according to the second light beam, wherein the light intensity information generated by the light sensing module comprises a first intensity signal related to first wavelength light, a second intensity signal related to second wavelength light, a third intensity signal related to third wavelength light and a fourth intensity signal related to fourth wavelength light. The wavelength of the first wavelength light is smaller than that of the second wavelength light, the wavelength of the second wavelength light is smaller than that of the third wavelength light, and the wavelength of the third wavelength light is smaller than that of the fourth wavelength light. The processing unit receives the light intensity information of the light sensing module and judges the second light beam according to the light intensity information, wherein the spectral distribution of the light beam accords with a target spectrum. When the processing unit judges that the absorption spectrum distribution of the solution to be detected accords with the target spectrum, positive result information is generated, and when the processing unit judges that the absorption spectrum distribution of the solution to be detected does not accord with the target spectrum, negative result information is generated. When the processing unit judges whether the spectrum distribution of the second light beam accords with the target spectrum according to the light intensity information, whether the second intensity signal, the third intensity signal and the fourth intensity signal are all larger than the first intensity signal or not is judged, and whether the second intensity signal and the fourth intensity signal are larger than the third intensity signal or not is judged.
When the second intensity signal, the third intensity signal and the fourth intensity signal are all greater than the first intensity signal, and when the second intensity signal and the fourth intensity signal are greater than the third intensity signal, the processing unit determines that the absorption spectrum distribution of the solution to be measured conforms to the target spectrum.
The mobile device with hemoglobin detection function of the present invention provides a hemoglobin detection function for users to use conveniently, and the mobile device is preferably a smart phone, a tablet computer, a personal digital assistant, etc., and the first light source is, for example, an auxiliary lighting LED lighting source of the smart phone or the tablet computer. The mobile device with the heme detection function is used for a user to operate and turn on the first light source, the first light beam and the light sensing module face to a container containing a solution to be detected, and when the first light beam passes through the solution to be detected and is reflected by a reflecting surface in the container, the second light beam is generated.
The solution to be measured mainly contains an aqueous solution of human body wastes, and preferably an aqueous solution carrying feces in a toilet bowl. When the excrement falls into the water in the toilet, if the excrement has abnormal occult blood, hemoglobin or red blood cells in the occult blood tend to be dissolved in the water solution in the toilet, so that the water solution contains hemoglobin or red blood cells. That is, the occult blood will also be present in the aqueous solution in the toilet bowl and will not be present only in part of the solid waste. Therefore, the first light beam of the mobile device is incident to the solution to be measured, namely the water solution of the toilet bowl containing excrement, and after the second light beam is generated by the reflection of the inner wall of the toilet bowl, the second light beam has a characteristic spectrum of the solution to be measured in the spectral range relative to the first light beam.
Further, the processing unit judges whether the absorption spectrum distribution of the solution to be detected conforms to a target spectrum according to the generated light intensity information after the light sensing module receives the second light beam, wherein the target spectrum is the absorption spectrum of the blood solution; when the processing unit judges that the absorption spectrum distribution of the solution to be detected does not conform to the target spectrum, the processing unit can confirm that the solution to be detected does not contain blood, which means that the excrement in the closestool does not contain occult blood, thereby generating negative result information.
The mobile device detects the aqueous solution with the excrement through spectral analysis, does not directly detect the excrement, and can effectively avoid false negative results caused by collecting part of excrement but not collecting the part of occult blood, thereby improving the reliability of detection results; by generating the first light beam and analyzing the second light beam, the user does not need to take excrement, stir or wait, thereby greatly reducing the complexity of the operation procedure. In addition, the mobile device analyzes the water solution in the toilet bowl containing the solid excrement, and directly detects the absorption spectrum of the solution to be detected, without adding a fluorescent agent, a reaction reagent, a reducing reagent and the like to the solution to be detected, thereby reducing the danger of human body contacting with chemical agents or environmental pollution. In summary, the present invention provides a fast, convenient and simple-programmed hemoglobin detection device for a user, so that the user can automatically detect whether occult blood is contained in excrement at home at any time, and immediately obtain a detection result according to information of the mobile device, thereby enabling the user to effectively perform home health management.
Drawings
FIG. 1 is a schematic rear plan view of a mobile device with hemoglobin detection of the present invention;
FIG. 2 is a block diagram of a mobile device with hemoglobin detection according to the present invention;
FIG. 3 is a flow chart of a hemoglobin detection method of the present invention;
FIG. 4 is a schematic diagram illustrating an exemplary embodiment of a mobile device with hemoglobin detection;
FIG. 5 is a schematic diagram of a target spectrum of a solution to be tested of the mobile device with hemoglobin detection function according to the present invention;
FIG. 6 is a flow chart of a first preferred embodiment of the method for detecting blood red color of the present invention;
FIG. 7 is a block diagram illustrating a light sensing module of a mobile device with hemoglobin detection according to an embodiment of the present invention;
FIG. 8 is a flow chart of a second preferred embodiment of the method for detecting blood red color of the present invention;
FIG. 9 is a flow chart of a third preferred embodiment of the method for detecting blood red color of the present invention;
FIG. 10 is a block diagram illustrating a light sensing module of a mobile device with hemoglobin detection according to a second preferred embodiment of the present invention;
FIGS. 11A and 11B are schematic plan views illustrating a mobile device with hemoglobin detection according to a fourth preferred embodiment of the present invention;
FIG. 12 is a schematic perspective view of a portion of a sixth preferred embodiment of a mobile device with hemoglobin detection function according to the present invention;
FIG. 13 is a schematic diagram illustrating a sixth preferred embodiment of a mobile device with hemoglobin detection according to the present invention in a using state;
FIG. 14 is a schematic perspective view of a seventh preferred embodiment of a mobile device with hemoglobin detection function according to the present invention;
FIG. 15 is a schematic diagram illustrating a seventh preferred embodiment of a mobile device with hemoglobin detection function according to the present invention in a using state.
Detailed Description
The technical means adopted by the invention to achieve the predetermined object of the invention are further described below with reference to the drawings and the preferred embodiments of the invention.
Referring to fig. 1 and 2, the present invention provides a mobile device 10 with a hemoglobin detection function, which includes a processing unit 11, a first light source 12 and a light sensing module 13. The first light source 12 emits a first light beam L1, the optical sensing module 13 is electrically connected to the processing unit 11, and receives a second light beam L2 generated by the first light beam L1 passing through a solution to be measured and reflecting, and generates light intensity information according to the second light beam L2, wherein the light intensity information generated by the optical sensing module 13 includes a first intensity signal S1 associated with a first wavelength light, a second intensity signal S2 associated with a second wavelength light, a third intensity signal S3 associated with a third wavelength light, and a fourth intensity signal S4 associated with a fourth wavelength light. The wavelength of the first wavelength light is smaller than that of the second wavelength light, the wavelength of the second wavelength light is smaller than that of the third wavelength light, and the wavelength of the third wavelength light is smaller than that of the fourth wavelength light. The processing unit 11 receives the light intensity information of the light sensing module 13 to determine whether the absorption spectrum distribution of the solution to be measured conforms to a target spectrum according to the light intensity information. When the processing unit 11 determines that the absorption spectrum distribution of the solution to be measured conforms to the target spectrum, a positive result is generated, and when the processing unit 11 determines that the absorption spectrum distribution of the solution to be measured does not conform to the target spectrum, a negative result is generated. In the preferred embodiment, when the processing unit 11 determines whether the absorption spectrum distribution of the solution to be tested conforms to the target spectrum according to the light intensity information, it determines whether the second intensity signal S2, the third intensity signal S3 and the fourth intensity signal S4 are all greater than the first intensity signal S1, and determines whether the second intensity signal S2 and the fourth intensity signal S4 are all greater than the third intensity signal S3. When the second intensity signal S2, the third intensity signal S3, and the fourth intensity signal S4 are all greater than the first intensity signal S1, and when the second intensity signal S2 and the fourth intensity signal S4 are greater than the third intensity signal S3, the processing unit 11 determines that the absorption spectrum distribution of the solution to be measured matches the target spectrum.
Referring to fig. 3, the present invention further provides a hemoglobin detection method executed by the mobile device 10, comprising the following steps:
generating and transmitting a first light beam L1 (S301);
receiving a second light beam L2 generated by the first light beam L1 passing through a solution to be measured and reflecting (S302);
generating a light intensity information according to the second light beam L2 (S303); wherein the light intensity information comprises a first intensity signal associated with a first wavelength of light S1, a second intensity signal associated with a second wavelength of light S2, a third intensity signal associated with a third wavelength of light S3, and a fourth intensity signal associated with a fourth wavelength of light S4; wherein the wavelength of the first wavelength light is smaller than that of the second wavelength light, the wavelength of the second wavelength light is smaller than that of the third wavelength light, and the wavelength of the third wavelength light is smaller than that of the fourth wavelength light;
judging whether the absorption spectrum distribution of the solution to be detected accords with a target spectrum or not according to the light intensity information (S304);
generating a positive result when the absorption spectrum of the solution to be measured distributes the target spectrum (S305);
generating negative result information when the absorption spectrum distribution of the solution to be detected does not accord with the target spectrum (S306);
when the absorption spectrum distribution of the solution to be tested is judged to be in accordance with the target spectrum according to the light intensity information, whether the second intensity signal S2, the third intensity signal S3 and the fourth intensity signal S4 are greater than the first intensity signal S1 and whether the second intensity signal S2 and the fourth intensity signal S4 are greater than the third intensity signal S3 are judged;
when the second intensity signal S2, the third intensity signal S3, and the fourth intensity signal S4 are all greater than the first intensity signal S1, and when the second intensity signal S2 and the fourth intensity signal S4 are greater than the third intensity signal S3, it is determined that the absorption spectrum distribution of the solution to be measured matches the target spectrum.
Referring to fig. 4, fig. 4 is a schematic diagram illustrating an application of the mobile device 10 with hemoglobin detection function according to the present invention. The user holds the mobile device 10 to face the solution to be tested in the toilet, and preferably to face a position where the water depth is shallow, so that the first light beam L1 is incident on the solution to be tested, and the light sensing module 13 receives the reflected second light beam. In this way, the second light beam L2 includes an absorption spectrum information of the solution to be measured. In this embodiment, the first to fourth light intensity signals S1 to S4 respectively represent the intensity signals of the absorption spectrum of the analyte solution.
Referring to FIG. 5, FIG. 5 is a schematic diagram of the absorption spectrum of a blood solution, i.e., the target spectrum in the preferred embodiment. In the preferred embodiment, the light generated by an LED light source includes most of visible light frequency bands, and the wavelength range thereof includes 450nm to 650nm, so that the light sensing module 13 captures light intensity signals of characteristic frequency bands with wavelengths of 500nm, 541nm, 550nm and 577nm according to the absorption spectrum of the blood solution and the frequency band range of the first light beam L1, so that the processing unit 11 can determine whether the absorption spectrum distribution of the solution to be measured conforms to the absorption spectrum of the blood solution.
From the absorption spectrum of fig. 5, it can be known that in the absorption spectrum of a blood solution, the light intensity at the wavelength of 541nm and the light intensity at the wavelength of 577nm are greater than the light intensity at the wavelength of 550nm, and the light intensity at the wavelength of 541nm, the light intensity at the wavelength of 550nm and the light intensity at the wavelength of 577nm are greater than the light intensity at the wavelength of 500 nm.
Referring to fig. 6, in a first preferred embodiment of the present invention, when the processing unit 11 determines whether the absorption spectrum distribution of the solution to be tested conforms to the target spectrum, it further determines whether the first intensity signal S1, the second intensity signal S2, the third intensity signal S3, and the fourth intensity signal S4 are in a staggered arrangement in sequence. When the second intensity signal S2, the third intensity signal S3, and the fourth intensity signal S4 are all greater than the first intensity signal S1, and when the second intensity signal S2 and the fourth intensity signal S4 are greater than the third intensity signal S3, and when the first intensity signal S1, the second intensity signal S2, the third intensity signal S3, and the fourth intensity signal S4 are in a staggered arrangement, the processing unit 11 determines that the absorption spectrum distribution of the solution to be measured matches the target spectrum.
That is, in step S304 of the hemoglobin detection method, that is, when determining whether the absorption spectrum distribution of the solution to be detected conforms to the target spectrum according to the light intensity information, it is further determined whether the first intensity signal S1, the second intensity signal S2, the third intensity signal S3, and the fourth intensity signal S4 are sequentially arranged in a staggered manner (S3041);
when the second intensity signal S2, the third intensity signal S3, and the fourth intensity signal S4 are all greater than the first intensity signal S1, and when the second intensity signal S2 and the fourth intensity signal S4 are greater than the third intensity signal S3, and when the first intensity signal S1, the second intensity signal S2, the third intensity signal S3, and the fourth intensity signal S4 are in staggered size in sequence, it is determined that the absorption spectrum distribution of the solution to be measured matches the target spectrum, and the positive result information is generated (S305).
The preferred embodiment further increases the accuracy of the processing unit 11 in determining the positive result information by adding a determination rule.
Referring to fig. 7, in the preferred embodiment, in order to obtain the first to fourth intensity signals S1-S4, preferably, the photo sensing module 13 includes a first filter BP1, a second filter BP2, a third filter BP3, a fourth filter BP4, a first photo detector PD1, a second photo detector PD2, a third photo detector PD3, and a fourth photo detector PD 4. Wherein the first photo-detector PD1 receives the light with the first wavelength through the first filter BP1 to generate the first intensity signal S1; the second photo-detector PD2 receives the second wavelength light through the second filter BP2 to generate the second intensity signal S2; the third photodetector PD3 receives the third wavelength light through the third filter BP3 to generate the third intensity signal S3; the fourth photo detector PD4 receives the fourth wavelength light through the fourth filter BP4 and generates the fourth intensity signal S4. The first filter BP1 only allows the first wavelength light with the wavelength of 500nm to pass through, the second filter BP2 only allows the second wavelength light with the wavelength of 541nm to pass through, the third filter BP3 only allows the third wavelength light with the wavelength of 550nm to pass through, and the fourth filter BP4 only allows the fourth wavelength light with the wavelength of 577nm to pass through. In this way, after the second light beam L2 passes through the first filter BP1, the second filter BP2, the third filter BP3 and the fourth filter BP4, the first wavelength light, the second wavelength light, the third wavelength light and the fourth wavelength light can be filtered out and respectively received by the first photo detector PD1, the second photo detector PD2, the third photo detector PD3 and the fourth photo detector PD4, and corresponding first to fourth light intensity signals S1 to S4 are generated.
In a second preferred embodiment of the present invention, the light intensity information generated by the light sensing module 13 further includes a fifth intensity signal S5 associated with a fifth wavelength of light and a sixth intensity signal S6 associated with a sixth wavelength of light. The wavelength of the fifth wavelength light is smaller than that of the first wavelength light, and the wavelength of the fourth wavelength light is smaller than that of the sixth wavelength light. In this embodiment, when the processing unit 11 determines that the absorption spectrum distribution of the solution to be measured conforms to the target spectrum according to the light intensity information, it further determines that the fifth intensity signal S5 is also greater than the first intensity signal S1, and determines that the fifth intensity signal S5, the first intensity signal S1, the second intensity signal S2, the third intensity signal S3 and the fourth intensity signal S4 are all greater than the sixth intensity signal S6, the processing unit 11 determines that the absorption spectrum distribution of the solution to be measured conforms to the target spectrum.
The wavelength of the fifth wavelength light is 450nm, and the wavelength of the sixth wavelength light is 600 nm.
That is, referring to fig. 8, in step S304 of the hemoglobin detection method, when it is determined whether the absorption spectrum distribution of the solution to be detected matches the target spectrum according to the light intensity information, it is further determined whether the fifth intensity signal S5 is greater than the first intensity signal S1, and whether the fifth intensity signal S5, the first intensity signal S1, the second intensity signal S2, the third intensity signal S3, and the fourth intensity signal S4 are all greater than the sixth intensity signal S6 (S3042).
When the second intensity signal S2, the third intensity signal S3, the fourth intensity signal S4 and the fifth intensity signal S5 are all greater than the first intensity signal S1, and when the second intensity signal S2 and the fourth intensity signal S4 are all greater than the third intensity signal S3, and when the first intensity signal S1, the second intensity signal S2, the third intensity signal S3, the fourth intensity signal S4 and the fifth intensity signal S5 are all greater than the sixth intensity signal S6, it is determined that the absorption spectrum distribution of the solution under test matches the target spectrum.
In the preferred embodiment, in addition to the original first to fourth light intensity signals S1 to S4, a fifth light intensity signal S55 having a wavelength of 450nm and a sixth light intensity signal S6 having a wavelength of 600nm are used.
Therefore, by increasing the number of the captured spectral feature points, the determination condition of whether the absorption spectrum distribution of the solution to be measured meets the target spectrum is increased, and therefore, the purpose of further increasing the accuracy and the reliability of the processing unit 11 in determining whether the positive result information is generated is achieved.
Referring to fig. 9, preferably, in a third preferred embodiment of the present invention, when determining whether the absorption spectrum distribution of the solution to be tested conforms to the target spectrum according to the light intensity information, it is further determined whether the fifth intensity signal S5, the first intensity signal S1, the second intensity signal S2, the third intensity signal S3, the fourth intensity signal S4 and the sixth intensity signal S6 are in a staggered arrangement in sequence (S3043).
When the fifth intensity signal S5, the second intensity signal S2, the third intensity signal S3 and the fourth intensity signal S4 are all greater than the first intensity signal S1, when the second intensity signal S2 and the fourth intensity signal S4 are greater than the third intensity signal S3, when the fifth intensity signal S5, the first intensity signal S1, the second intensity signal S2, the third intensity signal S3 and the fourth intensity signal S4 are all greater than the sixth intensity signal S6, and when the fifth intensity signal S5, the first intensity signal S1, the second intensity signal S2, the third intensity signal S3, the fourth intensity signal S4 and the sixth intensity signal S6 are in sequential magnitude arrangement, the absorption spectrum distribution of the solution under test is determined to be in conformity with the target spectrum.
Referring to fig. 10, in the preferred embodiment, in order to obtain the first to sixth intensity signals S1-S6, preferably, the photo sensing module 13 further includes a fifth photo detector PD5 and a sixth photo detector PD6, and a fifth filter BP5 and a sixth filter BP 6. The fifth photodetector PD5 receives the fifth wavelength light through the fifth filter BP5 to generate the fifth intensity signal S5; the sixth photo-detector PD6 receives the sixth wavelength light through the sixth filter BP6, and generates the sixth intensity signal S6. The fifth filter BP5 only passes the fifth wavelength light with a wavelength of 450nm, and the sixth filter BP6 only passes the sixth wavelength light with a wavelength of 600 nm. In this way, after the second light beam L2 passes through the first filter device BP1, the second filter device BP2, the third filter device BP3, the fourth filter device BP4, the fifth filter device BP5 and the sixth filter device BP6, the first wavelength light, the second wavelength light, the third wavelength light, the fourth wavelength light, the fifth wavelength light and the sixth wavelength light can be filtered out and respectively received by the first photodetector PD1, the second photodetector PD2, the third photodetector PD3, the fourth photodetector PD4, the fifth photodetector PD5 and the sixth photodetector PD6, so as to respectively generate the corresponding first to sixth light intensity signals S1 to S6.
In the preferred embodiment, the light sensing module 13 further extracts the fifth wavelength light with a wavelength of 450nm and the sixth wavelength light with a wavelength of 600nm, that is, extracts a total of six feature points in the frequency band included in the first light beam L1, and adds two feature points to determine whether the spectrum of the second light beam L2 matches the target spectrum, thereby further increasing the accuracy of the detection result.
In a fourth preferred embodiment of the present invention, the mobile device 10 is an intelligent mobile device, such as a smart phone or a tablet computer. The mobile device 10 includes a housing 15 and a display module 16, the processing unit 11 and the first light source 12 are disposed in the housing 15, the housing 15 has a top surface 151 and a back surface 152 opposite to each other, and the display module 16 is disposed on the top surface 151 of the housing 15. When the processing unit 11 generates a positive result message, the processing unit 11 controls the display module 16 to display a positive result graph. When the processing unit 11 generates a negative result message, the processing unit 11 controls the display module 16 to display a negative result graph.
The processing unit 11 is, for example, a main processor of the mobile device 10, and the display module 16 is a display panel of the mobile device 10, for example, a touch-control liquid crystal display panel. When the user holds the mobile device 10, the first light source 12 is turned on, and the detection is performed towards the water solution in the toilet, and the processing unit 11 determines that the detection is completed according to the light intensity information, the display module 16 is controlled to display a relative diagram according to the generated detection result. For example, as shown in fig. 11A, when the processing unit 11 generates a negative result message, a hollow blood drop shape graph can be displayed to indicate that the detection result is that the solution to be detected does not contain blood or hemoglobin; as shown in fig. 11B, when the processing unit 11 generates a positive result message, a solid blood drop shape graph can be displayed to show that the detection result is that the solution to be detected contains blood or hemoglobin, so as to provide a concise and understandable detection result prompt for the user.
Referring to fig. 1 and 4, in a fifth preferred embodiment of the present invention, the mobile device 10 further includes a camera module 17 electrically connected to the processing unit 11. In the preferred embodiment, the camera module 17, the first light source 12 and the light sensing module 13 are all disposed on the back surface 152 of the housing 15, and the processing unit 11 executes an auxiliary detection application program, the camera module 17 receives and stores a target image of the solution to be detected, the processing unit 11 controls the display module 16 to display the target image, and controls the display module 16 to display a recommended detection position index graph X in the target image.
When the first light beam L1 is incident to a shallow depth position of the water solution in the toilet, the incident water solution of the first light beam L1 and the reflected second light beam L2 are less likely to be disturbed or blocked by the floating objects, and the second light beam L2 with better intensity and thus better detection result can be obtained, so that the preferred detection position is a portion of the liquid in the toilet near the front end, that is, a shallow liquid position in the toilet in general, according to the shape of the inner wall in most toilets. Therefore, after receiving the target image, the processing unit 11 displays the recommended detection position indicator graph X at the front position of the solution in the toilet bowl in the target image, and provides a reference of the recommended detection position for the user, so that the user can aim the first light beam generated by the first light source 12 at the recommended detection position.
Referring to fig. 12 and 13, in a sixth preferred embodiment of the present invention, the light-focusing assembly 18 is further included, the light-focusing assembly 18 is disposed outside the housing 15 and is engaged with the housing 15, and is disposed corresponding to the first light source 12 on the back surface 152 of the housing 15, so as to converge the first light beam L1 generated by the first light source 12, converge the divergence angle thereof, and increase the intensity of the first light beam L1 per unit area. Preferably, the light-gathering assembly 18 includes at least one light-gathering lens therein.
In the preferred embodiment, the camera module 17 is a camera module equipped with the smart mobile device 10, and the first light source 12 is an LED light source equipped with the smart mobile device 10 for auxiliary lighting or providing a flash function when taking a picture, so that no additional arrangement is required.
Since the first light source 12 directly uses the LED light source originally provided in the smart mobile device, the LED light source originally provided in the smart mobile device generally provides illumination, and thus the divergence angle is large and the illumination intensity per unit area is small. To achieve the detection object of the present invention, a light-focusing assembly 18 is further disposed outside the first light source L1 of the mobile device, such that the first light beam L1 generated by the first light source 12 passes through the light-focusing assembly 18, and the first light beam L1 is converged to obtain a more concentrated first light beam L1, such that the first light beam can be intensively incident on the solution to be detected in the toilet bowl, and a second light beam with better intensity is obtained after being reflected, thereby improving the detection accuracy. The light-gathering assembly 18 is detachable, and when the user does not need to perform hemoglobin detection, the light-gathering assembly 18 is removed, and the first light source 12 can be used as a general auxiliary illumination light source.
When the user starts the assistant detection application, the mobile device 10 simultaneously starts the camera module 17 and displays the image received by the camera module 17 on the display module 16. When the user holds the mobile device 10 and faces the back 152 of the housing 15 toward the toilet to perform detection, the camera lens receives images of the toilet and the aqueous solution therein, the auxiliary detection application program determines that a target image is received at the moment according to the main shape characteristics of the toilet, and controls the display module 16 to display a recommended detection position index diagram.
Referring to fig. 14 and 15, in a seventh preferred embodiment of the invention, the housing 15 has a first side surface 153 and a second side surface 154 opposite to each other, two opposite sides of the first side surface 153 are respectively connected to the top surface 151 and the back surface 152, two opposite sides of the second side surface 154 are respectively connected to the top surface 151 and the back surface 152, and the light sensing module 13 and the first light source 12 are both disposed on the first side surface 153 of the housing 15. In the preferred embodiment, the light sensing module 13 and the first light source 12 are designed in another way, that is, are disposed at the side of the mobile device 10, so that a user can easily hold the mobile device 10 and direct the first light source 12 and the light sensing module 13 toward the solution to be tested. Preferably, the first light source 12 is provided for the detection function of the light sensing module 13, and an auxiliary light source for assisting a general photographing function of the photographing module 17 is not required to be provided at the same time, so that the first light beam L1 having strong concentration and directivity can be provided for the detection function of the present invention, so as to obtain a good detection result.
In the preferred embodiment, the mobile device 10 further includes a control button 19, and the control button 19 is preferably disposed on the first side 153 or the second side 154 of the housing 15. The control button 19 is electrically connected to the processing unit 11, when the control button 19 is switched to a start detection state, the first light source 12 generates the first light beam L1, and the light sensing module 13 receives the second light beam L2 and generates light intensity information to be provided to the processing unit 11.
Although the present invention has been described with reference to the preferred embodiments, it should be understood that various changes, substitutions and alterations can be made herein without departing from the spirit and scope of the invention as defined by the appended claims.

Claims (10)

1. A mobile device with hemoglobin detection function, comprising:
a processing unit;
a first light source for emitting a first light beam;
the optical sensing module is electrically connected with the processing unit, receives a second light beam generated after the first light beam passes through a solution to be detected and is reflected, and generates light intensity information according to the second light beam, wherein the light intensity information generated by the optical sensing module comprises a first intensity signal related to first wavelength light, a second intensity signal related to second wavelength light, a third intensity signal related to third wavelength light and a fourth intensity signal related to fourth wavelength light; wherein the wavelength of the first wavelength light is less than the wavelength of the second wavelength light, the wavelength of the second wavelength light is less than the wavelength of the third wavelength light, and the wavelength of the third wavelength light is less than the wavelength of the fourth wavelength light;
the processing unit receives light intensity information of the light sensing module and judges whether the absorption spectrum distribution of the solution to be detected accords with a target spectrum or not according to the light intensity information;
when the processing unit judges that the absorption spectrum distribution of the solution to be detected accords with the target spectrum, positive result information is generated;
when the processing unit judges that the absorption spectrum distribution of the solution to be detected does not accord with the target spectrum, negative result information is generated; wherein the content of the first and second substances,
when the processing unit judges whether the absorption spectrum distribution of the solution to be detected conforms to the target spectrum according to the light intensity information, whether the second intensity signal, the third intensity signal and the fourth intensity signal are all larger than the first intensity signal or not is judged, and whether the second intensity signal and the fourth intensity signal are all larger than the third intensity signal or not is judged;
when the second intensity signal, the third intensity signal and the fourth intensity signal are all greater than the first intensity signal, and when the second intensity signal and the fourth intensity signal are greater than the third intensity signal, the processing unit determines that the absorption spectrum distribution of the solution to be measured conforms to the target spectrum.
2. The mobile device with hemoglobin detection function of claim 1,
when the processing unit judges whether the absorption spectrum distribution of the solution to be detected accords with the target spectrum according to the light intensity information, the processing unit further judges whether the first intensity signal, the second intensity signal, the third intensity signal and the fourth intensity signal are sequentially in a size staggered arrangement;
when the second intensity signal, the third intensity signal and the fourth intensity signal are all greater than the first intensity signal, and when the second intensity signal and the fourth intensity signal are greater than the third intensity signal, and when the first intensity signal, the second intensity signal, the third intensity signal and the fourth intensity signal are in size staggered arrangement in sequence, the processing unit determines that the absorption spectrum distribution of the solution to be measured conforms to the target spectrum.
3. The mobile device with hemoglobin detection function of claim 1,
the light intensity information generated by the light sensing module further comprises a fifth intensity signal associated with a fifth wavelength of light and a sixth intensity signal associated with a sixth wavelength of light; wherein the wavelength of the fifth wavelength light is less than the wavelength of the first wavelength light, and the wavelength of the fourth wavelength light is less than the wavelength of the sixth wavelength light;
when the processing unit judges whether the absorption spectrum distribution of the solution to be detected conforms to the target spectrum according to the light intensity information, further judging whether the fifth intensity signal is greater than the first intensity signal, and judging whether the fifth intensity signal, the first intensity signal, the second intensity signal, the third intensity signal and the fourth intensity signal are all greater than the sixth intensity signal;
when the fifth intensity signal, the second intensity signal, the third intensity signal and the fourth intensity signal are all greater than the first intensity signal, and when the second intensity signal and the fourth intensity signal are all greater than the third intensity signal, and when the fifth intensity signal, the first intensity signal, the second intensity signal, the third intensity signal and the fourth intensity signal are all greater than the sixth intensity signal, the processing unit determines that the absorption spectrum distribution of the solution to be measured conforms to the target spectrum.
4. The mobile device with hemoglobin detection function of claim 3,
when the processing unit judges whether the spectrum distribution of the second light beam accords with the target spectrum according to the light intensity information, further judging whether the fifth intensity signal, the first intensity signal, the second intensity signal, the third intensity signal, the fourth intensity signal and the sixth intensity signal are in staggered arrangement in sequence;
when the fifth intensity signal, the second intensity signal, the third intensity signal and the fourth intensity signal are all greater than the first intensity signal, and when the second intensity signal and the fourth intensity signal are all greater than the third intensity signal, and when the fifth intensity signal, the first intensity signal, the second intensity signal, the third intensity signal and the fourth intensity signal are all greater than the sixth intensity signal, and when the fifth intensity signal, the first intensity signal, the second intensity signal, the third intensity signal, the fourth intensity signal and the sixth intensity signal are in size staggered arrangement in sequence, the processing unit determines that the absorption spectrum distribution of the solution to be tested conforms to the target spectrum.
5. The mobile device of claim 1, wherein the light sensing module comprises:
a first filter device;
a first optical detector for receiving said first wavelength light through said first filter device and generating said first intensity signal;
a second filter device;
a second optical detector for receiving the second wavelength light through the second filter device to generate the second intensity signal;
a third filter device;
a third photodetector, receiving said third wavelength light through said third filter, and generating said third intensity signal;
a fourth filter device; and
a fourth photodetector receiving said fourth wavelength light through said fourth filter device and generating said fourth intensity signal.
6. The mobile device with hemoglobin detection function of claim 3, wherein the light sensing module comprises:
a first filter device;
a first optical detector for receiving said first wavelength light through said first filter device and generating said first intensity signal;
a second filter device;
a second optical detector for receiving the second wavelength light through the second filter device to generate the second intensity signal;
a third filter device;
a third photodetector, receiving said third wavelength light through said third filter, and generating said third intensity signal;
a fourth filter device;
a fourth photodetector, receiving said fourth wavelength light through said fourth filter device, and generating said fourth intensity signal;
a fifth filter device;
a fifth photodetector, receiving said fifth wavelength light through said fifth filter device, and generating said fifth intensity signal;
a sixth filter device; and
a sixth optical detector, receiving said sixth wavelength light through said sixth filter device, generating said sixth intensity signal.
7. The mobile device with hemoglobin detection function of any one of claims 1-6,
the mobile device is an intelligent mobile device and further comprises a shell and a display module, the processing unit and the first light source are arranged in the shell, the shell is provided with a top surface and a back surface which are opposite, and the display module is arranged on the top surface of the shell; wherein the content of the first and second substances,
when the processing unit generates a positive result message, the processing unit controls the display module to display a positive result graph;
when the processing unit generates negative result information, the processing unit controls the display module to display a negative result graph.
8. The mobile device with hemoglobin detection function of claim 7, further comprising:
the photographic module is electrically connected with the processing unit;
the photographic module, the first light source and the light sensing module are respectively arranged on the back surface of the shell;
when the processing unit executes an auxiliary detection application program, the photographing module receives and stores a target image of the solution to be detected, and the processing unit controls the display module to display the target image and controls the display module to display a suggested detection position index graphic representation in the target image.
9. The mobile device with hemoglobin detection function of claim 8, further comprising:
the light-gathering assembly is arranged on the shell and clamped with the shell, corresponds to the first light source on the back of the shell, and gathers the first light beam generated by the first light source.
10. The mobile device with hemoglobin detection function of claim 7,
the shell is provided with a first side surface and a second side surface which are opposite, two opposite edges of the first side surface are respectively connected with the top surface and the back surface, and two opposite edges of the second side surface are respectively connected with the top surface and the back surface;
the first light source and the light sensing module are arranged on a first side surface of the shell;
the mobile device with hemoglobin detection function further comprises:
the control key is electrically connected with the processing unit and is arranged on the second side surface of the shell of the mobile device;
when the control key is started, the first light source generates the first light beam, and the light sensing module receives the second light beam.
CN201910286917.5A 2019-04-10 2019-04-10 Mobile device with heme detection function Active CN111812043B (en)

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