CN111790063A - Superconducting rotating frame for laser accelerating proton cancer treatment device - Google Patents

Superconducting rotating frame for laser accelerating proton cancer treatment device Download PDF

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Publication number
CN111790063A
CN111790063A CN202010644201.0A CN202010644201A CN111790063A CN 111790063 A CN111790063 A CN 111790063A CN 202010644201 A CN202010644201 A CN 202010644201A CN 111790063 A CN111790063 A CN 111790063A
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magnetic field
mixed
local
superconducting
deflection
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朱昆
王科栋
颜学庆
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Peking University
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Peking University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1077Beam delivery systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1077Beam delivery systems
    • A61N5/1081Rotating beam systems with a specific mechanical construction, e.g. gantries
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1085X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy characterised by the type of particles applied to the patient
    • A61N2005/1087Ions; Protons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1092Details

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

The invention discloses a superconducting rotating frame for a laser-accelerated proton cancer treatment device, belonging to the field of medical instruments. The superconducting rotating machine frame comprises a scanning treatment head, a vacuum system, a beam transmission system and a beam diagnosis system, wherein a plurality of local achromatic transmission sections are arranged in the beam transmission system, each local achromatic transmission section comprises a plurality of mixed field type superconducting deflection magnets, the mixed field type superconducting deflection magnets provide a mixed magnetic field, the mixed magnetic field is a high-order magnetic field such as a quadrupole magnetic field and a hexapole magnetic field which are superposed on a deflection magnetic field, and the superconducting rotating machine frame has a deflection function and a focusing function. The invention adopts the technology of local dispersion elimination, avoids overlarge envelope increase of beam current in the transmission process of the rotating frame, and adopts the technology of mixed field type superconducting magnet, thereby reducing the total weight of the rotating frame and the manufacturing cost of the rotating frame.

Description

Superconducting rotating frame for laser accelerating proton cancer treatment device
Technical Field
The invention belongs to the field of medical instruments, and particularly relates to a superconducting rotating frame for a laser-accelerated proton cancer treatment device.
Background
Proton cancer therapy is a very advantageous radiotherapy technique because proton energy deposition in the body has a bragg peak, and therefore, the proper proton energy and lateral irradiation range are selected, which can form the maximum dose irradiation at the tumor site in the patient. Compared with the traditional radiotherapy technologies such as X-ray, gamma ray, electron and the like, the method has the advantages of being more accurate and causing the peripheral normal tissues to be less damaged by irradiation, and is a development direction of a new generation of radiotherapy technology. Proton cancer treatment devices typically use cyclotron, synchrotron, or linear accelerator devices. The application of a novel laser acceleration technology in the aspect of cancer treatment is also a research hotspot, the existing proton cancer treatment device usually designs a rotating rack for irradiating patients from multiple angles, but the design scheme adopted by many rotating racks uses a normal-temperature magnet, and because a beam distribution system needs to realize many functions, the rotating rack has heavy equipment weight which reaches hundreds of tons, and the whole rotating rack is very expensive in manufacturing cost.
Disclosure of Invention
The invention aims to provide a superconducting rotating frame for a laser acceleration proton cancer treatment device, which adopts a local dispersion elimination technology to avoid the increase of the envelope of a beam in the transmission process of the rotating frame, so that the total cost is increased.
The technical scheme of the invention is that the superconducting rotating frame for the laser acceleration proton cancer treatment device comprises a scanning treatment head, a vacuum system, a beam transmission system and a beam diagnosis system, and is characterized in that: the beam transmission system is provided with a plurality of local achromatic transmission sections, each local achromatic transmission section comprises a plurality of mixed field type superconducting deflection magnets, the mixed field type superconducting deflection magnets are used for providing a mixed magnetic field, the mixed magnetic field is formed by superposing high-order magnetic fields such as a quadrupole magnetic field and a hexapole magnetic field on a dipolar deflection magnetic field, and the mixed magnetic field has the functions of deflection, focusing and the like.
The local dispersion-eliminating transmission section comprises more than two mixed field type superconducting deflection magnets, a slit is arranged between the mixed field type superconducting deflection magnets, and the slit is used for selecting the energy of beam current.
The local achromatic transmission section further comprises a plurality of quadrupole lenses for adjusting beam parameters, and the quadrupole lenses are symmetrically arranged on two sides of the plane of the mixed field type superconducting deflection magnet.
The beam transmission system is provided with more than two local dispersion elimination transmission sections, wherein two adjacent local dispersion elimination transmission sections can be directly connected. Or a quadrupole lens group is arranged between two adjacent local achromatic transmission sections and is used for adjusting beam parameters.
The invention has the beneficial effects that:
the invention adopts the technology of local dispersion elimination and a novel mixed field type superconducting deflection magnet, controls the proton beam flow through a plurality of local dispersion elimination transmission sections, realizes the rising, horizontal deflection and falling of the beam flow, and finally vertically irradiates the tumor part of a patient. The invention adopts the local dispersion eliminating technology to avoid the overlarge envelope increase of the high-energy dispersed beam current generated by the laser in the transmission process of the rotating frame, and reduces the aperture of the magnet, thereby reducing the manufacturing cost of the magnet.
Drawings
FIG. 1 is a schematic view of a rotating gantry of a laser proton accelerator of the present invention;
FIG. 2 is a schematic view of a hybrid field superconducting deflection magnet of the present invention providing a hybrid magnetic field;
FIG. 3 is a schematic diagram of a partially-depolarized-dispersion transmission segment according to the present invention;
figure 1-scanning treatment head; 2- -vacuum system; 3-beam diagnosis system; 4-local de-dispersion transmission section; 5- -mixed field superconducting deflection magnet; 6- -quadrupole lens.
Detailed Description
The invention is further illustrated by the following examples. It is noted that the disclosed embodiments are intended to aid in further understanding of the invention, but those skilled in the art will appreciate that: various substitutions and modifications are possible without departing from the spirit and scope of the invention and appended claims. Therefore, the invention should not be limited to the embodiments disclosed, but the scope of the invention is defined by the appended claims.
The rotating frame for the laser proton accelerator comprises a scanning treatment head 1, a vacuum system 2, a beam diagnosis system 3 and a beam transmission system, wherein the scanning treatment head 1 comprises a scanning magnet and a dose detector and a position detector of a gas ionization chamber which are matched with the scanning magnet; the vacuum system 2 comprises a beam vacuum pipeline, a cavity, a vacuum pump and a valve; the beam diagnosis system 3 is used for monitoring information such as beam position, distribution and electric quantity in the beam vacuum pipeline and comprises a cavity BPM beam position detector and a gas ionization chamber position detector which are arranged along a beam line, and a gas ionization chamber dose detector and a position detector which are arranged at a treatment head; the beam transmission system is used for realizing the rising, horizontal deflection and falling of beams, and is provided with a plurality of local dispersion eliminating transmission sections 4, wherein each local dispersion eliminating transmission section 4 comprises one or more mixed field type superconductive deflection magnets 5 and 0 or more quadrupole lenses 6. The mixed field type superconducting deflection magnet can provide a mixed magnetic field structure, the mixed magnetic field is formed by superposing high-order magnetic fields such as a quadrupole magnetic field, a hexapole magnetic field and the like on the basis of a deflection magnetic field, and meanwhile, the mixed magnetic field has the functions of deflection, focusing and the like, so that beam transmission can not be influenced by energy dispersion. The invention relates to a mixed field superconducting deflection magnet CCT (Canted Cosine theta) or DCT (discrete Cosine transform) superconducting magnet.
Embodiment one of the invention
The invention provides a rotating frame comprising three sections of local de-dispersion transmission sections, as shown in figure 1, beam current is deflected from a first section of local de-dispersion transmission section, the deflection angle of a dipolar deflection magnetic field in the local de-dispersion transmission section is 20-45 degrees, the deflection magnetic field is 1.5T-4.5T, the magnetic field gradient of a quadrupole magnetic field is 10-50T/m, and the deflection radius is 0.3 m-1.2 m. The beam direction is changed from horizontal to vertical or inclined upwards (between 45 and 90 degrees), meanwhile, energy selection is carried out on the beam in a local de-dispersion section, and the energy selection function is realized by adjusting the width of a slit between two superconducting magnets so as to adjust the energy spectrum shape of the beam. After passing through the first deflection transmission section, a beam diagnosis system, a BPM beam position detector or a gas ionization chamber position detector is installed and used for measuring beam parameters. After the beam diagnosis system, a quadrupole lens group is installed, and beam parameters such as beam envelope size and the like are controlled by using the focusing function of the quadrupole lens group (optionally installed or not installed), wherein the envelope size is usually between 10mm and 60mm, the magnetic field gradient of the quadrupole lens is between 5 and 30T/m, and the aperture is 40 to 100 mm. And a second section of local achromatic dispersion transmission section is arranged behind the quadrupole lens to adjust the beam in the vertical upward or oblique beam direction to be in the horizontal direction, a quadrupole lens group (which can be optionally installed or not) is arranged behind the second section of local achromatic dispersion transmission section to control beam parameters such as beam envelope size, and the parameter range of the quadrupole lens is the same as that of the first section. And a gas ionization chamber is arranged behind the quadrupole lens group to measure beam position parameters. And a third partial dispersion eliminating transmission section is arranged behind the gas ionization chamber, and deflects the beam current from the horizontal direction to the vertical downward direction. And two scanning magnets are arranged in the treatment head and respectively scan in the x direction and the y direction, two beam position detectors are arranged behind the two scanning magnets to measure the beam position, two beam dose detectors are arranged behind the two beam position detectors, and the beam is irradiated in a large irradiation field by a scanning method.
Embodiment two of the invention
The invention provides a rotating frame comprising two sections of local dispersion eliminating transmission sections, which is characterized in that a beam is deflected from a first section of local dispersion eliminating transmission section, the beam direction is changed from horizontal to vertical upward or inclined upward, the deflection angle of a dipolar deflection magnetic field in the local dispersion eliminating transmission section is 20-45 degrees, the deflection magnetic field is 1.5T-4.5T, the magnetic field gradient of a quadrupole magnetic field is 10-50T/m, the deflection radius is 0.3 m-1.2 m, meanwhile, energy selection can be carried out on the beam in the dispersion eliminating section, the energy selection function is realized by adjusting the width of a slit between two superconducting magnets, and the energy spectrum shape of the beam is adjusted. After passing through the first deflection transmission section, a beam diagnosis system, a BPM beam position detector or a gas ionization chamber position detector is installed and used for measuring beam parameters. After the beam diagnosis system, a quadrupole lens group (which can be optionally installed or not installed) is installed, and beam parameters such as beam envelope size and the like are controlled by using the focusing function of the quadrupole lens group. And a second section of local dispersion elimination transmission section is arranged behind the quadrupole lens to adjust the beam in the beam direction vertically upwards or obliquely downwards, the deflection angle of a two-pole deflection magnetic field in the local dispersion elimination transmission section is 45-90 degrees, the deflection magnetic field is 1.5T-4.5T, the magnetic field gradient of the quadrupole magnetic field is 10-50T/m, and the deflection radius is 0.3 m-1.2 m. The treatment head is provided with two scanning magnets for scanning in the x direction and the y direction respectively, two beam position detectors are arranged behind the two scanning magnets for measuring the beam position, two beam dose detectors are arranged behind the two beam position detectors, and the beam is irradiated in a large irradiation field by a scanning method.
Although the present invention has been described with reference to the preferred embodiments, it is not intended to be limited thereto. Those skilled in the art can make numerous possible variations and modifications to the present invention, or modify equivalent embodiments, using the methods and techniques disclosed above, without departing from the scope of the present invention. Therefore, any simple modification, equivalent change and modification made to the above embodiments according to the technical essence of the present invention are still within the scope of the protection of the technical solution of the present invention, unless the contents of the technical solution of the present invention are departed.

Claims (5)

1. A superconductive rotating frame for a laser acceleration proton cancer treatment device comprises a scanning treatment head, a vacuum system, a beam transmission system and a beam diagnosis system, and is characterized in that: the beam transmission system is provided with a plurality of local achromatic transmission sections, each local achromatic transmission section comprises a plurality of mixed field type superconducting deflection magnets, the mixed field type superconducting deflection magnets are used for providing a mixed magnetic field, and the mixed magnetic field is formed by superposing a four-pole magnetic field or a six-pole magnetic field on the basis of a two-pole deflection magnetic field.
2. The superconducting rotating gantry for laser-accelerated proton cancer therapy device according to claim 1, wherein the local-achromatic transmission section comprises two or more mixed-field superconducting deflection magnets, and a slit is installed between the mixed-field superconducting deflection magnets and used for selecting the energy of the beam.
3. A superconducting rotating gantry for a laser-accelerated proton cancer treatment apparatus according to claim 1 or 2, wherein the local achromatic transmission section further comprises a plurality of quadrupole lenses for beam parameter adjustment, the quadrupole lenses being symmetrically arranged at both sides of the mixed-field superconducting deflection magnet.
4. The superconducting rotating gantry for laser-accelerated proton cancer therapy apparatus according to claim 1, wherein said beam delivery system has two or more local-achromatic transmission segments, and two adjacent local-achromatic transmission segments are directly connected.
5. The superconducting rotating gantry for laser-accelerated proton carcinostatic device according to claim 1, wherein the beam transmission system has two or more local-achromatic transmission sections, and a quadrupole lens set is installed between two adjacent local-achromatic transmission sections, and the quadrupole lens set is used for adjusting beam parameters.
CN202010644201.0A 2020-07-07 2020-07-07 Superconducting rotating frame for laser accelerating proton cancer treatment device Pending CN111790063A (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115413105A (en) * 2022-09-19 2022-11-29 中国科学院近代物理研究所 360 that can realize multi-terminal delivery o Superconducting rotating beam line
CN116585623A (en) * 2023-05-06 2023-08-15 华中科技大学 Large momentum acceptance superconductive rotating frame for proton cancer treatment device
CN117080039A (en) * 2023-09-05 2023-11-17 广东省新兴激光等离子体技术研究院 Analysis magnetic field device and ion implanter
WO2024032049A1 (en) * 2022-08-09 2024-02-15 合肥中科离子医学技术装备有限公司 Superconducting rotating rack and proton therapy device
CN117080039B (en) * 2023-09-05 2024-05-31 广东省新兴激光等离子体技术研究院 Analysis magnetic field device and ion implanter

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024032049A1 (en) * 2022-08-09 2024-02-15 合肥中科离子医学技术装备有限公司 Superconducting rotating rack and proton therapy device
CN115413105A (en) * 2022-09-19 2022-11-29 中国科学院近代物理研究所 360 that can realize multi-terminal delivery o Superconducting rotating beam line
CN116585623A (en) * 2023-05-06 2023-08-15 华中科技大学 Large momentum acceptance superconductive rotating frame for proton cancer treatment device
CN116585623B (en) * 2023-05-06 2023-12-19 华中科技大学 Large momentum acceptance superconductive rotating frame for proton cancer treatment device
CN117080039A (en) * 2023-09-05 2023-11-17 广东省新兴激光等离子体技术研究院 Analysis magnetic field device and ion implanter
CN117080039B (en) * 2023-09-05 2024-05-31 广东省新兴激光等离子体技术研究院 Analysis magnetic field device and ion implanter

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Application publication date: 20201020

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Denomination of invention: Superconducting rotating frame for laser accelerated proton cancer treatment device

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Record date: 20230412

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