CN111774116B - Reagent feeding device for microfluidic detection - Google Patents
Reagent feeding device for microfluidic detection Download PDFInfo
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- CN111774116B CN111774116B CN202010791301.6A CN202010791301A CN111774116B CN 111774116 B CN111774116 B CN 111774116B CN 202010791301 A CN202010791301 A CN 202010791301A CN 111774116 B CN111774116 B CN 111774116B
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- 239000003153 chemical reaction reagent Substances 0.000 title claims abstract description 121
- 238000001514 detection method Methods 0.000 title claims abstract description 30
- 239000004809 Teflon Substances 0.000 claims abstract description 36
- 229920006362 Teflon® Polymers 0.000 claims abstract description 36
- 229910001220 stainless steel Inorganic materials 0.000 claims abstract description 24
- 239000010935 stainless steel Substances 0.000 claims abstract description 24
- 238000009434 installation Methods 0.000 claims description 32
- 230000001105 regulatory effect Effects 0.000 claims description 20
- 239000011324 bead Substances 0.000 claims description 17
- 230000008878 coupling Effects 0.000 claims description 8
- 238000010168 coupling process Methods 0.000 claims description 8
- 238000005859 coupling reaction Methods 0.000 claims description 8
- 230000000149 penetrating effect Effects 0.000 claims description 3
- 230000000694 effects Effects 0.000 claims description 2
- 210000003205 muscle Anatomy 0.000 claims 2
- 238000011160 research Methods 0.000 description 6
- 238000010586 diagram Methods 0.000 description 5
- 238000000034 method Methods 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 3
- 229910000831 Steel Inorganic materials 0.000 description 2
- 238000010276 construction Methods 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 239000010959 steel Substances 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- -1 electronics Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
Abstract
The invention relates to the technical field of microfluidics, in particular to a reagent feeding device for microfluidic detection, which comprises a cover plate, a support, a stainless steel tube, a reagent bottle seat, a reagent bottle, an adjusting seat, a Teflon tube, a moving plate and a screw rod stepping motor, wherein a Teflon tube groove is fixedly arranged at the upper part of the support.
Description
Technical Field
The invention relates to the technical field of microfluidics, in particular to a reagent supply device for microfluidic detection.
Background
The microfluidic technology is a technology for precisely controlling and manipulating microscale fluid, namely, a technology for integrating basic operation units such as sample preparation, reaction, separation, detection and the like in biological, chemical and medical analysis processes on a microfluidic chip with a few square centimeters and automatically completing the whole analysis process, and has been developed into a brand-new research field crossing disciplines such as biology, chemistry, medicine, fluid, electronics, materials, machinery and the like due to great potential in the fields such as biology, chemistry, medicine and the like.
At present, research on microfluidic detection is focused on research on chip development and research on devices (such as a control valve, a magnetic bead control device, a heating device and the like) directly contacted with the chip, research on reagent supply devices for the microfluidic is less, some automatic supply systems are rough, at most, the test requirements can be met only, the reagent replacement process is particularly troublesome, and the reagent bottle with different specification capacities and the supply requirements of different amounts of reagents can not be met, so that the research and the development and the use of microfluidic detection equipment are seriously affected. In a specific operation, a precondition for realizing the automatic microfluidic detection device is to have a reliable reagent feeding device, so that a microfluidic reagent feeding device which is reliable in operation is needed.
Disclosure of Invention
The invention aims to provide a reagent feeding device for microfluidic detection, which can be used for rapidly and conveniently replacing reagents, has small occupied space, simple and reliable movement and convenient connection with a quantitative pump, can meet the feeding requirements of reagent bottles with different specifications and capacities and different quantities of reagents, and has better compatibility with different microfluidic detection equipment.
In order to achieve the above purpose, the invention adopts the following technical scheme:
the utility model provides a microfluidic detection is with reagent feeding device, includes apron, support, nonrust steel pipe, reagent bottle seat, reagent bottle, regulating seat, teflon pipe, fly leaf and lead screw step motor, support upper portion fixedly provided with teflon tube bank for the teflon pipe of external constant delivery pump is installed in the teflon tube bank, the apron install teflon tube bank upper portion position and compress tightly teflon pipe in the teflon tube bank, teflon tube lower part connect nonrust steel pipe, support lower part fixed be provided with lead screw step motor mounting panel, lead screw step motor install on lead screw step motor mounting panel, at lead screw step motor power take off end install the lead screw, the support on fixed mounting have the lead screw support, the other end of lead screw install on the lead screw support, the support on set up the spout that is used for the reagent bottle seat to install, the reagent bottle seat install the spout position on the support, be used for driving the fly leaf that removes the reagent bottle seat and install on the teflon tube bank and link to each other on the screw seat, the reagent bottle seat is installed in the screw bottle seat is installed to the screw half-type of setting up with the screw groove, the reagent bottle seat is installed to the reagent bottle seat is fixed in the reagent bottle of the regulation type.
The reagent bottle seat constitute by backup pad, transitional coupling drive installing frame and roof, the backup pad install and drive installing frame lower part and with transitional coupling and link to each other fixedly at transitional coupling, the roof install and drive installing frame upper portion position and with transitional coupling and link to each other fixedly, for the semi-open mounting groove that is used for reagent bottle installation in transitional coupling drive installing frame, fixed mounting is provided with the locating plate that is used for chucking reagent bottle on the roof on semi-open mounting groove upper portion, processing has the stainless steel pipe guiding hole that is used for stainless steel pipe to run through the installation on the roof between the locating plate, transitional coupling drive installing frame's back fixed mounting have the guide post, the guide post can run through the spout of seting up on the support and install on the movable plate, set up the locating hole in the lower part of guide post, set up the arc recess that is used for conveniently taking out article in the semi-open mounting groove on the both sides wall of transitional coupling drive installing frame, processing has the draw-in groove that is used for adjusting seat installation from top to bottom.
The regulating seat comprises a regulating seat body, clamping plates and limiting ribs, wherein the regulating seat body is internally provided with a through groove which is used for installing the reagent bottle and is opened at the upper end and the lower end, the regulating seat body at the two sides of the through groove is fixedly provided with the limiting ribs which are used for limiting the clamping of the reagent bottle, the clamping plates are fixedly arranged at the two sides of the outer part of the regulating seat body, and the regulating seat body can be installed on a clamping groove on a transitional connection driving installation frame through the clamping plates so that the regulating seat can be installed in the reagent bottle seat.
The movable plate comprises a mounting connecting plate, a thread bush and a side plate, wherein an internal thread hole is formed in the thread bush, the thread bush is mounted on a screw rod through the internal thread hole and is connected with the screw rod in a threaded fit manner, the thread bush is fixedly mounted on the mounting connecting plate, and the side plate for touching the limit switch is fixedly mounted on the mounting connecting plate.
The upper part of the support is fixedly provided with a cover plate mounting hole, and the cover plate is mounted on the support through the cover plate mounting hole.
The support on fixedly be provided with the support mounting hole, the support pass through the support mounting hole and install on micro-fluidic detection equipment.
The upper part of the support is provided with a limit switch mounting seat, and the limit switch mounting seat is provided with a limit switch for limiting the moving plate.
The support on still fixed mounting have the locating bead mounting hole, the locating bead mounting hole in install the locating bead that is used for guaranteeing reagent bottle working position reliability.
The beneficial effects of the invention are as follows: the reagent feeding device for microfluidic detection provided by the invention has the advantages that the whole structure design is very scientific, the installation and the use are convenient, the reagent bottle for containing the reagent can be conveniently and rapidly replaced mainly through the combined cooperation of the structural elements such as the reagent bottle seat, the adjusting seat, the moving plate, the screw rod stepping motor and the like, the whole occupied space is small, the whole structure movement is simple and reliable, the connection with a quantitative pump is convenient, the reagent bottles with different specification and capacity can be met, the feeding requirements of different amounts of reagents are met, and the reagent feeding device has good compatibility with different microfluidic detection equipment.
Drawings
FIG. 1 is a schematic view of the overall construction of the installation of the present invention;
FIG. 2 is a schematic diagram of the overall construction of the installation of the present invention;
FIG. 3 is a schematic view of the structure of the support of the present invention;
FIG. 4 is a second schematic view of the structure of the support of the present invention;
FIG. 5 is a schematic diagram of a reagent bottle holder according to the present invention;
FIG. 6 is a schematic diagram of a reagent bottle holder according to the present invention;
FIG. 7 is a schematic view of the structure of the adjusting seat of the present invention;
FIG. 8 is a schematic diagram of a reagent bottle mounting structure of different specifications;
FIG. 9 is a schematic diagram II of a reagent bottle mounting structure of different specifications;
FIG. 10 is a schematic view showing the structure of the adjusting seat installed in the reagent bottle seat in the present invention;
FIG. 11 is a schematic view of the structure of a reagent bottle according to the present invention;
FIG. 12 is a schematic view of the structure of a moving plate according to the present invention;
the reference numerals in the figures are: 1-cover plate, 2-support, 3-stainless steel tube, 4-reagent bottle seat, 5-reagent bottle, 6-adjusting seat, 7-Teflon tube, 8-limit switch, 9-positioning bead, 10-moving plate, 11-lead screw stepping motor, 12-lead screw, 201-cover plate mounting hole, 202-support mounting hole, 203-chute, 204-positioning bead mounting hole, 205-Teflon tube slot, 206-lead screw support, 207-limit switch mounting seat, 208-lead screw stepping motor mounting plate, 401-stainless steel tube guiding hole, 402-guide column, 403-clamping slot, 404-positioning plate, 405-positioning hole, 406-arc groove, 407-top plate, 408-transitional connection driving mounting frame, 409-supporting plate, 410-semi-open mounting slot, 601-clamping plate, 602-limiting rib, 603-adjusting seat body, 604-through slot, 1001-internal threaded hole, 1002-side plate, 1003-threaded sleeve and 1004-mounting connecting plate.
Detailed Description
Specific example 1: the core of the present invention is to provide a reagent feeding device for microfluidic detection, which mainly enables the reagent bottle 5 containing the reagent to be conveniently and rapidly replaced through the combined cooperation of structural elements such as a reagent bottle seat 4, an adjusting seat 6, a moving plate 10, a screw stepping motor 11, etc., in order to enable the technical scheme of the present invention to be better understood by those skilled in the art, the present invention is further described in detail below with reference to the accompanying drawings and the specific embodiments, and it should be noted that when an element is referred to as being "fixed to" or "arranged on" another element, it can be directly or indirectly connected to the other element. When an element is referred to as being "connected to" another element, it can be directly or indirectly connected to the other element. The terms "left" and "right" used in this specification to denote orientations are each referenced to a particular structure shown in the drawings, and are not to be construed as limiting the structure. As shown in fig. 1-12 of the specification, a reagent feeding device for microfluidic detection mainly comprises a cover plate 1, a support 2, a stainless steel tube 3, a reagent bottle seat 4, a reagent bottle 5, an adjusting seat 6, a teflon tube 7, a moving plate 10 and a screw stepping motor 11, wherein a cover plate mounting hole 201 is fixedly arranged at the upper part of the support 2, the cover plate 1 is arranged on the support 2 through the cover plate mounting hole 201, a teflon tube groove 205 is fixedly arranged at the upper part of the support 2, the teflon tube 7 for externally connecting a quantitative pump is arranged in the teflon tube groove 205, the cover plate 1 is arranged at the upper part of the teflon tube groove 205 at the upper part of the support 2 and tightly presses the teflon tube 7 in the teflon tube groove 205, the lower part of the teflon tube 7 is connected with the stainless steel tube, the lower part of the stainless steel tube is arranged in the reagent bottle 5, a screw stepping motor mounting plate 208 is fixedly arranged at the lower part of the support 2, the screw stepping motor 11 is arranged on the screw stepping motor mounting plate 208, the screw 12 is arranged at the power output end of the screw stepping motor 11, the screw support 206 is fixedly arranged on the support 2, the other end part of the screw 12 is arranged on the screw support 206, the support 2 is provided with a chute 203 for mounting the reagent bottle seat 4, the reagent bottle seat 4 consists of a supporting plate 409, a transitional driving mounting frame 408 and a top plate 407, the supporting plate 409 is fixedly arranged at the lower part of the transitional driving mounting frame 408, the top plate 407 is fixedly arranged at the upper part of the transitional driving mounting frame 408, a semi-open mounting groove 410 for mounting the reagent bottle 5 is arranged in the transitional driving mounting frame 408, a positioning plate 404 for clamping the reagent bottle 5 is fixedly arranged on the top plate 407 at the upper part of the semi-open mounting groove 410, stainless steel tube guide holes 401 for penetrating and installing stainless steel tubes are processed on a top plate 407 between positioning plates 404, the stainless steel tubes are installed in reagent bottles 5 after penetrating through the stainless steel tube guide holes 401, guide columns 402 are fixedly installed on the back surface of a transitional connection driving installation frame 408, the guide columns 402 can penetrate through sliding grooves 203 formed in a support 2 and are installed on a moving plate 10, positioning holes 405 are formed in the lower portion of the guide columns 402, arc-shaped grooves 406 for conveniently taking out articles in a semi-open installation groove 410 are formed in two side walls of the transitional connection driving installation frame 408, clamping grooves 403 for installing adjusting seats are processed in the upper portion and the lower portion of the arc-shaped grooves 406, each adjusting seat consists of an adjusting seat body 603, clamping plates 601 and limiting ribs 602, through grooves 604 with upper ends and lower ends being opened are formed in the adjusting seat body 603 for installing the reagent bottles 5, the regulating seat body 603 at two sides of the through groove 604 is fixedly provided with a limiting rib 602 for clamping and limiting the reagent bottle 5, two sides of the outside of the regulating seat body 603 are fixedly provided with a clamping plate 601, the regulating seat body 603 can be arranged on the clamping groove 403 on the transitional connection driving installation frame 408 through the clamping plate 601 so that the regulating seat 6 can be arranged in the reagent bottle seat 4, the moving plate 10 for driving the reagent bottle seat 4 to move up and down is arranged on the screw rod 12, the moving plate 10 comprises an installation connection plate 1004, a thread bush 1003 and a side plate 1002, the thread bush 1003 is provided with an internal thread hole 1001, the thread bush 1003 is arranged on the screw rod 12 through the internal thread hole 1001 and is connected with the screw rod 12 in a thread fit manner, the thread bush 1003 is fixedly arranged on the installation connection plate 1004, the installation connection plate 1004 is connected with the transitional connection driving installation frame 408 through the guide post 402, the side plate 1002 for touching the limiting switch 8 is fixedly arranged on the installation connection plate 1004, the support 2 is fixedly provided with a support mounting hole 202, the support 2 is mounted on the microfluidic detection device through the support mounting hole 202, the upper portion of the support 2 is further provided with a limit switch mounting seat 207, the limit switch mounting seat 207 is provided with a limit switch 8 for limiting the moving plate 10, the support 2 is further fixedly provided with a positioning bead mounting hole 204, and the positioning bead mounting hole 204 is internally provided with a positioning bead 9 for ensuring the reliability of the working position of the reagent bottle 5. The specific working process of the invention is that, as shown in fig. 1 and 2 of the specification, the reagent bottle 5 is placed in the reagent bottle seat 4, because the detection requirement (the reagent dosage is small, the reagent is difficult to preserve for a long time at room temperature or when the test equipment is used), the specification of the reagent bottle 5 is often required to be adjusted, in order to increase the universality of the microfluidic detection device, the reagent bottle seat 4 is provided with the adjusting seat 6, and according to the detection requirement, the reagent bottle 5 can be placed in the semi-open mounting groove 410 in the reagent bottle seat 4 so as to adapt to reagent bottles 5 with different specifications (further note that the height and the size of the reagent bottle 5 used in the invention are consistent, and the diameter and the capacity are variable). The reagent bottle seat 4 is connected with the moving plate 10 and can move along the sliding groove 203 in the support 2, a threaded hole is arranged in the threaded sleeve 1003 in the moving plate 10 and is matched with the lead screw 12 of the lead screw stepping motor 11, and when the lead screw stepping motor 11 drives the lead screw 12 to rotate, the lead screw 12 can drive the threaded sleeve 1003 to move up and down on the lead screw. The position of the moving plate 10 is controlled by a limit switch 8, the limit switch 8 is arranged on a limit switch mounting seat 207 at the upper and lower parts of the chute 203, the lower limit switch controls the initial position, and the upper limit switch controls the feeding position. The feeding pipeline consists of a stainless steel pipe 3 and a Teflon pipe 7, one end of the stainless steel pipe 3 is fixed on the support 2, the other end of the stainless steel pipe is arranged in a guide hole of the reagent bottle seat, the stainless steel pipe 3 gradually enters the reagent bottle 5 along with the rising of the reagent bottle seat 4, and finally the bottom of the stainless steel pipe 3 and the bottom of the reagent bottle 5 are separated by 1-2mm. One end of the Teflon tube 7 is connected with the stainless steel tube 3, is fixed by the cover plate 1 through a Teflon tube groove 205 on the support 2, and the other end of the Teflon tube is connected with a quantitative pump (not shown in the figure) and is co-fed to the microfluidic chip through the quantitative pump. The number of the positioning beads 9 is 2, and the positioning beads are matched with the positioning holes 405 (in a hemispherical shape) on the reagent bottle seat 4 to ensure the reliability of the working position of the reagent bottles 5, and the number of the reagent bottles 5 in the reagent feeding device for microfluidic detection can be adjusted according to the detection requirement, and is not limited to 6 in the figure. In the specification of the invention, in the attached drawing 3 and the attached drawing 4, cover plate mounting holes 201 are arranged at the left and right 2 parts of the top of a bracket, the cover plate 1 is connected with the cover plate through bolts, support mounting holes 202 are arranged at the four corners of the bracket, the four corners of the bracket are externally connected with microfluidic detection equipment, a chute 203 plays a role in guiding a reagent bottle seat 4 to ensure that a reagent bottle 5 moves up and down, a positioning bead mounting hole 204 and a limit switch mounting seat 207 are also arranged on the bracket, the positions of the positioning bead mounting holes and the limit switch mounting seat are arranged according to the specific height of the reagent bottle 5, a Teflon tube groove 205 is a semicircular groove, the Teflon tube 7 has good guiding and fixing effects, a screw stepping motor mounting plate 208 and a screw stepping motor 11 are fixed through bolts, a screw support 206 supports the tail end of a screw 12 to ensure that the screw 12 moves stably, as shown in the specification of the attached drawing 5, the specification attached drawing 6, the specification attached drawing 7, the specification attached drawing 8, the specification attached drawing 9 and the specification attached drawing 10, in the figure, a stainless steel tube 3 enters a reagent bottle 5 through a stainless steel guide hole 401, a guide column 402 is matched with a sliding groove 203 on a support 2 to penetrate through the sliding groove 203, a threaded hole is arranged on the guide column 402 and is connected with a moving plate 10 through a connecting screw, a reagent bottle seat 4 can only move up and down along the guide sliding groove 203 after being fixed, a clamping groove 403 is matched with a clamping plate 601 on an adjusting seat 6 to fix the adjusting seat 6, a positioning plate 404 can clamp the reagent bottle 5 in the up-down height direction, a positioning hole 405 is matched with a positioning bead 9 to play a role in fixing positions, when a replacement reagent is required to be taken out, an operator can take down the reagent bottle 5 or the adjusting seat 6 through a finger tightly through arc-shaped grooves 406 formed on two side walls of a transitional connection driving installation frame 408, the reagent bottle 5 is convenient and rapid, as shown in an attached figure 11 of the specification, the bottom of the reagent bottle 5 is conical, the structure can make the utilization rate of the reagent in the reagent bottle 5 highest and reduce residual liquid, as shown in the attached figure 12 of the specification, an internal threaded hole 1001 on a threaded sleeve 1003 is matched with a screw rod 12, and rotates along with the screw rod 12 to drive a movable plate 10 to move up and down integrally, and a side plate 1002 is used for touching a limit switch 8 so as to remind an operator of paying attention. The foregoing has shown and described the basic principles, principal features and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, and that the above embodiments and descriptions are merely illustrative of the principles of the present invention, and various changes and modifications may be made without departing from the spirit and scope of the invention, which is defined in the appended claims.
Claims (6)
1. The reagent feeding device for microfluidic detection is characterized by comprising a stainless steel tube, a reagent bottle seat, a reagent bottle, an adjusting seat, a Teflon tube, a moving plate and a screw rod stepping motor, wherein the Teflon tube groove is fixedly arranged at the upper part of a support, the Teflon tube for externally connecting a quantitative pump is arranged in the Teflon tube groove, a cover plate is arranged at the upper part of the support and tightly presses the Teflon tube in the Teflon tube groove, the Teflon tube groove is a semicircular groove, the Teflon tube is provided with good guiding and fixing effect, the lower part of the Teflon tube is connected with the stainless steel tube, the screw rod stepping motor is fixedly arranged at the lower part of the support, a screw rod is arranged at the power output end of the screw rod stepping motor, the support is fixedly provided with the screw rod, the other end part of the screw rod is arranged on the support, the support is provided with a chute for installing the reagent bottle seat, the reagent bottle seat is arranged at the chute part on the support, the reagent bottle seat is used for driving the moving plate to move, the reagent bottle seat is arranged on the screw rod seat, the reagent bottle seat is arranged in the adjusting seat, and the reagent bottle seat is arranged in the groove, the reagent bottle seat is arranged on the reagent bottle seat, and the reagent bottle seat is matched with the screw bottle seat is arranged on the screw bottle seat, and can be fixed by the screw seat, and is arranged on the screw seat, and is fixed on the screw seat, and has a structure;
the reagent bottle seat consists of a supporting plate, a transitional driving installation frame and a top plate, wherein the supporting plate is installed at the lower part of the transitional driving installation frame and fixedly connected with the transitional driving installation frame, the top plate is installed at the upper part of the transitional driving installation frame and fixedly connected with the transitional driving installation frame, a semi-open type installation groove for installing the reagent bottle is formed in the transitional driving installation frame, a positioning plate for clamping the reagent bottle is fixedly installed on the top plate at the upper part of the semi-open type installation groove, a stainless steel pipe guide hole for penetrating and installing a stainless steel pipe is formed in the top plate between the positioning plates, a guide post is fixedly installed at the back of the transitional driving installation frame, the guide post can penetrate through a sliding groove formed in the support and is installed on the movable plate, a positioning hole is formed in the lower part of the guide post, arc grooves for conveniently taking out articles in the semi-open type installation groove are formed in the two side walls of the transitional driving installation frame, and clamping grooves for installing the regulating seat are formed in the upper part and lower part of the arc grooves;
the regulating seat comprises regulating seat body, cardboard and spacing muscle, regulating seat body in be used for the open logical groove of upper and lower end of reagent bottle installation, fixed mounting has the spacing muscle that is used for spacing to reagent bottle chucking on the regulating seat body of logical groove both sides, has the cardboard in the outside both sides fixed mounting of regulating seat body, regulating seat body can be installed on the draw-in groove on transitional coupling drive installing frame through the cardboard and then make regulating seat can install in reagent bottle seat.
2. The reagent feeding device for microfluidic detection according to claim 1, wherein the moving plate comprises an installation connecting plate, a threaded sleeve and a side plate, the threaded sleeve is provided with an internal threaded hole, the threaded sleeve is installed on the screw rod through the internal threaded hole and is connected with the screw rod in a threaded fit manner, the threaded sleeve is fixedly installed on the installation connecting plate, and the side plate for touching the limit switch is fixedly installed on the installation connecting plate.
3. The reagent feeding apparatus for microfluidic detection according to claim 1, wherein the upper part of the support is fixedly provided with a cover plate mounting hole, and the cover plate is mounted on the support through the cover plate mounting hole.
4. The reagent feeding apparatus for microfluidic detection according to claim 1, wherein the holder is fixedly provided with a holder mounting hole, and the holder is mounted on the microfluidic detection device through the holder mounting hole.
5. The reagent feeding device for microfluidic detection according to claim 1, wherein a limit switch mounting seat is mounted on the upper portion of the support, and a limit switch for limiting the moving plate is mounted on the limit switch mounting seat.
6. The reagent feeding device for microfluidic detection according to claim 1, wherein the support is fixedly provided with a positioning bead mounting hole, and a positioning bead for ensuring the reliability of the working position of the reagent bottle is arranged in the positioning bead mounting hole.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010791301.6A CN111774116B (en) | 2020-08-07 | 2020-08-07 | Reagent feeding device for microfluidic detection |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010791301.6A CN111774116B (en) | 2020-08-07 | 2020-08-07 | Reagent feeding device for microfluidic detection |
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| CN111774116A CN111774116A (en) | 2020-10-16 |
| CN111774116B true CN111774116B (en) | 2024-01-09 |
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| CN205720241U (en) * | 2016-04-14 | 2016-11-23 | 四川迈克生物医疗电子有限公司 | Reagents loaded device |
| CN106269587A (en) * | 2016-08-30 | 2017-01-04 | 福州派利德电子科技有限公司 | IC chip cliff cut style testing, sorting machine automatic collecting device |
| CN109517732A (en) * | 2017-09-19 | 2019-03-26 | 德诺杰亿（北京）生物科技有限公司 | Integrated DNA analysis system |
| CN208537555U (en) * | 2018-06-07 | 2019-02-22 | 天津康信华诺科技有限公司 | A kind of platelet aggregation detection device |
| CN109603950A (en) * | 2018-11-27 | 2019-04-12 | 迪瑞医疗科技股份有限公司 | A kind of reagent bottle clamp assemblies, autoloading structure and its loading method |
| CN213050679U (en) * | 2020-08-07 | 2021-04-27 | 河南固创生物科技有限公司 | Reagent supply device for micro-fluidic detection |
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| CN111774116A (en) | 2020-10-16 |
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