CN111759290A - Flexible physiological signal detection device - Google Patents
Flexible physiological signal detection device Download PDFInfo
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- CN111759290A CN111759290A CN201910263158.0A CN201910263158A CN111759290A CN 111759290 A CN111759290 A CN 111759290A CN 201910263158 A CN201910263158 A CN 201910263158A CN 111759290 A CN111759290 A CN 111759290A
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- physiological signal
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- signal sensor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/0205—Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
- A61B5/02055—Simultaneously evaluating both cardiovascular condition and temperature
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6844—Monitoring or controlling distance between sensor and tissue
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- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
Abstract
The present disclosure relates to a flexible physiological signal detection device. The method comprises the following steps: the flexible substrate bears the physiological signal sensor and the force application component and attaches the device to the body surface of the organism; the physiological signal sensor is positioned on the flexible substrate and close to the surface of the body surface of the organism, is partially embedded into the flexible substrate and is directly contacted with the body surface of the organism to acquire physiological signals; the force application control component determines a power supply voltage for supplying power to the force application component according to the physiological signal; the force application component is positioned in the flexible substrate and above the physiological signal sensor and is not in contact with the physiological signal sensor, and applies pressure to the physiological signal sensor through deformation generated after power supply of the power supply voltage so as to change the contact force between the physiological signal sensor and the body surface of a living body. The device that this disclosed embodiment provided can make the two closely laminate according to the contact force of physiology signal adjusting device and organism body surface, has improved the accuracy and the stability of the physiology signal that detects.
Description
Technical Field
The present disclosure relates to the field of electronic technology, and in particular, to a flexible physiological signal detection device.
Background
The ductile flexible electronic technology can be summarized as an emerging electronic technology for manufacturing organic/inorganic material electronic devices on flexible/ductile plastic or thin metal substrates, and the manufactured ductile flexible electronic devices have wide application prospects in the fields of information, energy, medical treatment, national defense and the like by unique flexibility/ductility and efficient and low-cost manufacturing processes. However, in the related art, the manufactured flexible electronic device has poor reliability and is susceptible to electrostatic interference.
In the related technology, the extensible flexible electronic device is tightly attached to the skin of a human body to monitor various health physiological indexes of the human body, such as pulse, blood pressure, body temperature and the like, and the change of data is fed back to achieve the purposes of preventing and diagnosing diseases. However, when the human body needs to be monitored for a long time, the extensible flexible electronic device is not attached to the skin due to the influences of human body movement, skin sweat, clothing friction and the like. In the related art, the extensible flexible electronic device is tightly attached to the skin by adding a patch with strong adhesion force, mechanically clamping and the like, but the mode brings discomfort or even certain injury to the skin of a human body.
Disclosure of Invention
In view of this, the present disclosure provides a flexible physiological signal detection device.
According to an aspect of the present disclosure, there is provided a flexible physiological signal detection apparatus, the apparatus including: a flexible substrate, a physiological signal sensor, a force application component and a force application control component,
the flexible substrate is used for bearing the physiological signal sensor and the force application component and is also used for attaching the device to the body surface of a living body;
the physiological signal sensor is positioned on the flexible substrate and close to the surface of the body surface of the organism, is partially embedded into the flexible substrate, and is used for directly contacting with the body surface of the organism and acquiring the physiological signal of the organism;
the force application control component is connected with the physiological signal sensor and the force application component and used for determining a power supply voltage for supplying power to the force application component according to the physiological signal;
the force application component is positioned in the flexible substrate, is positioned above the physiological signal sensor and is not in contact with the physiological signal sensor, and is used for applying pressure to the physiological signal sensor through deformation generated after power supply by the power supply voltage so as to change the contact force between the physiological signal sensor and the body surface of the organism.
For the above apparatus, in one possible implementation manner, the apparatus further includes:
and the adhesive layer is positioned on the surface of the flexible substrate close to the body surface of the organism so as to increase the adhesiveness between the flexible substrate and the body surface of the organism.
With regard to the above device, in one possible implementation, determining a supply voltage for powering the force application member from the physiological signal includes:
determining a current contact force between the physiological signal sensor and the body surface of the living body according to the intensity of the physiological signal;
determining a pressure difference value according to the difference value of the current contact force and the target contact force;
and determining the power supply voltage according to the current power supply voltage of the force application component, the pressure difference value and the corresponding relation between the power supply voltage difference value and the pressure difference value.
For the above device, in one possible implementation, the force application member is disposed in the flexible substrate, and the material of the force application member includes an electroactive polymer.
With regard to the above device, in a possible implementation manner, the force application parts are arranged in an array, or the force application parts are of an integrated structure.
With regard to the above device, in a possible implementation, the distance between the force application member and the physiological signal sensor is less than or equal to a distance threshold, or the thickness of the device is 0.5mm to 5 mm.
With regard to the above device, in one possible implementation manner, the surface of the physiological signal sensor contacting the body surface of the living body and the surface of the flexible substrate attached to the body surface of the living body are at the same horizontal plane.
For the above apparatus, in one possible implementation, the physiological signal includes at least one of: body temperature signal, blood pressure signal, heart rate signal.
The flexible physiological signal detection device provided by the embodiment of the disclosure comprises: the device comprises a flexible substrate, a physiological signal sensor, a force application component and a force application control component, wherein the flexible substrate is used for bearing the physiological signal sensor and the force application component and is also used for attaching the device to the body surface of an organism; the physiological signal sensor is positioned on the flexible substrate and close to the surface of the body surface of the organism, is partially embedded into the flexible substrate and is used for directly contacting with the body surface of the organism and collecting the physiological signal of the organism; the force application control component is connected with the physiological signal sensor and the force application component and used for determining a power supply voltage for supplying power to the force application component according to the physiological signal; the force application component is positioned in the flexible substrate and above the physiological signal sensor and is not in contact with the physiological signal sensor, and is used for applying pressure to the physiological signal sensor through deformation generated after power supply by the power supply voltage so as to change the contact force between the physiological signal sensor and the body surface of the organism. The flexible physiological signal detection device provided by the embodiment of the disclosure can ensure that the device and the body surface of the organism can be tightly attached according to the contact force between the physiological signal adjustment device and the body surface of the organism, and improves the accuracy and stability of the detected physiological signal.
Other features and aspects of the present disclosure will become apparent from the following detailed description of exemplary embodiments, which proceeds with reference to the accompanying drawings.
Drawings
The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate exemplary embodiments, features, and aspects of the disclosure and, together with the description, serve to explain the principles of the disclosure.
Fig. 1 and 2 are schematic structural diagrams of a flexible physiological signal detection device according to an embodiment of the present disclosure.
Fig. 3 illustrates a cross-sectional view of a flexible physiological signal detection device according to an embodiment of the present disclosure.
Fig. 4 shows a schematic diagram of an application scenario of a flexible physiological signal detection apparatus according to an embodiment of the present disclosure.
Fig. 5 illustrates a cross-sectional view of a flexible physiological signal detection device according to an embodiment of the present disclosure.
Detailed Description
Various exemplary embodiments, features and aspects of the present disclosure will be described in detail below with reference to the accompanying drawings. In the drawings, like reference numbers can indicate functionally identical or similar elements. While the various aspects of the embodiments are presented in drawings, the drawings are not necessarily drawn to scale unless specifically indicated.
The word "exemplary" is used exclusively herein to mean "serving as an example, embodiment, or illustration. Any embodiment described herein as "exemplary" is not necessarily to be construed as preferred or advantageous over other embodiments.
Furthermore, in the following detailed description, numerous specific details are set forth in order to provide a better understanding of the present disclosure. It will be understood by those skilled in the art that the present disclosure may be practiced without some of these specific details. In some instances, methods, means, elements and circuits that are well known to those skilled in the art have not been described in detail so as not to obscure the present disclosure.
Fig. 1 and 2 are schematic structural diagrams of a flexible physiological signal detection device according to an embodiment of the present disclosure. Fig. 3 illustrates a cross-sectional view of a flexible physiological signal detection device according to an embodiment of the present disclosure. As shown in fig. 1, 2 and 3, the device 1 comprises a flexible substrate 11, a physiological signal sensor 12, a force application member 13 and a force application control member (not shown).
And the flexible substrate 11 is used for carrying the physiological signal sensor 12 and the force application part 13 and is also used for attaching the device to the body surface of a living body. The physiological signal sensor 12 is located on the flexible substrate 11 at a position close to the surface of the body surface of the living body, is partially embedded in the flexible substrate 11, and is used for directly contacting with the body surface of the living body to acquire the physiological signal of the living body. And the force application control component is connected with the physiological signal sensor 12 and the force application component 13 and is used for determining the power supply voltage for supplying power to the force application component 13 according to the physiological signal. And the force application component 13 is positioned in the flexible substrate 11 and above the physiological signal sensor 12 and is not in contact with the physiological signal sensor 12, and is used for applying pressure to the physiological signal sensor 12 through deformation generated after power supply by the power supply voltage so as to change the contact force between the physiological signal sensor 12 and the body surface of a living body.
In this embodiment, the force application control member may be flexible and may be disposed inside the flexible substrate to reduce the volume of the apparatus. The force application control component may also be disposed outside the flexible substrate, as the present disclosure is not limited thereto. The material used for preparing the flexible substrate may be a flexible material such as Polydimethylsiloxane (PDMS).
In the present embodiment, fig. 4 shows a schematic diagram of an application scenario of a flexible physiological signal detection device according to an embodiment of the present disclosure. As shown in fig. 4, the flexible physiological signal detection device can be directly attached to the back of the hand (i.e. the body surface of the living body) of the human body to detect the physiological signal of the human body.
In this embodiment, the pre-prepared physiological signal sensor can be transferred to the flexible substrate by a transfer technique or the like. The physiological signal sensor may be made by extensible flexible electronics.
In this embodiment, the force application component can be prepared directly during the process of preparing the flexible substrate by using a mask or other techniques, or the required force application component can be prepared in advance and then implanted into the flexible substrate. The skilled person can set the preparation of the force applying component and the implantation of the flexible substrate according to actual needs, and the disclosure is not limited thereto.
The flexible physiological signal detection device provided by the embodiment of the disclosure can ensure that the device and the body surface of the organism can be tightly attached according to the contact force between the physiological signal adjustment device and the body surface of the organism, and improves the accuracy and stability of the detected physiological signal.
In one possible implementation, the device may further comprise an adhesive layer. The adhesive layer is positioned on the surface of the flexible substrate close to the body surface of the living body to increase the adhesion between the flexible substrate and the body surface of the living body. This improves the adhesion of the device to the body surface.
In one possible implementation, determining a supply voltage for powering the force application component from the physiological signal may include:
determining the current contact force between the physiological signal sensor and the body surface of the organism according to the intensity of the physiological signal;
determining a pressure difference value according to the difference value of the current contact force and the target contact force;
and determining the power supply voltage according to the current power supply voltage of the force application component, the pressure difference value and the corresponding relation between the power supply voltage difference value and the pressure difference value.
In this implementation, the target contact force may be set according to the type of physiological signal that needs to be acquired, the position of the device on the body surface of the living body, and the like. The larger the contact force of the target is, the closer the device is contacted with the body surface of the organism, and the higher the accuracy and stability of the detected physiological signal are.
In one possible implementation, the force application member may be disposed in a flexible substrate, and the material of the force application member may include an electroactive polymer.
In this implementation, the smart material (Intelligent material) is a novel functional material that can sense external stimuli, can judge and appropriately process, and can be executed by itself. Among them, an Electroactive polymer (EAP) material such as an ionic polymer-Metal Composites (IPMC) is used as a material of the force application member. Electroactive polymers are one type of smart materials that have relatively special electrical and mechanical properties. The EAP material can generate larger deformation after being induced by an electric field, has large deformation rate and quick response, and can quickly recover to the original shape after the electric field is eliminated. By means of the characteristics of the electroactive polymer, the force application component generates deformation after being electrified, and transmits pressure to the physiological signal sensor through the force generated by deformation. The higher the supply voltage received by the force application member, the greater the deformation generated by the force application member.
In one possible implementation, the force application members may be arranged in an array, or alternatively, the force application members may be of unitary construction.
In this implementation, the force application member may be composed of a plurality of force application units, the material of the force application units is an electroactive polymer, and the plurality of force application units are arranged in an array in the flexible substrate. The force application unit can be in the shape of a disk, a sphere, an ellipsoid, a column, etc. For example, the plurality of force application units of the force application component are spherical and distributed in a lattice manner in the flexible substrate, so that the force application component can generate out-of-plane displacement due to the distribution of the plurality of force application units in the lattice manner under the action of the power supply voltage, and provide pressure to the physiological signal sensor below.
In this implementation, the force application member may also be an integral structure with a certain shape, which ensures that the force application member can apply pressure to the physiological signal sensor below under the action of the power supply voltage.
In one possible implementation, the distance between the force application component and the physiological signal sensor may be less than or equal to a distance threshold.
In this implementation, the force application member and the signal sensor are not in contact with each other, and adverse effects of the power supply voltage on the physiological signal sensor can be avoided. The distance between the force application component and the physiological signal sensor can be smaller than or equal to a distance threshold value, so that the force application component can apply force to the physiological signal sensor under the action of the power supply voltage, and meanwhile, the physiological signal sensor cannot be damaged by pressure applied by the force application component. The distance threshold may be set according to the flexibility of the physiological signal sensor, the size change of the force application member before and after deformation, and the like, which is not limited by the present disclosure.
In one possible implementation, the thickness of the device may be 0.5mm to 5 mm.
In this implementation, reducing the thickness of the device can improve the adhesion effect of the flexible substrate and the body surface of the living body, and enhance the contact force between the physiological signal sensor and the body surface of the living body.
Fig. 5 illustrates a cross-sectional view of a flexible physiological signal detection device according to an embodiment of the present disclosure. In one possible implementation, as shown in fig. 5, the surface of the physiological signal sensor contacting the body surface of the living body and the surface of the flexible substrate attached to the body surface of the living body are at the same horizontal plane.
In this implementation, the physiological signal sensor can be completely embedded in the flexible substrate, so that the surface of the physiological signal sensor contacting with the body surface of the living body and the surface of the flexible substrate attached to the body surface of the living body are in the same level, and the attachment between the device and the body surface of the living body is improved.
In one possible implementation, the physiological signal may include at least one of a body temperature signal, a blood pressure signal, a heart rate signal, and the like, which are related to the physiology of the living organism, and the disclosure is not limited thereto.
It should be noted that, although the flexible physiological signal detection device is described above by taking the above-mentioned embodiment as an example, those skilled in the art can understand that the disclosure should not be limited thereto. In fact, the user can flexibly set each part according to personal preference and/or actual application scene as long as the technical scheme of the disclosure is met.
Having described embodiments of the present disclosure, the foregoing description is intended to be exemplary, not exhaustive, and not limited to the disclosed embodiments. Many modifications and variations will be apparent to those of ordinary skill in the art without departing from the scope and spirit of the described embodiments. The terms used herein were chosen in order to best explain the principles of the embodiments, the practical application, or technical improvements to the techniques in the marketplace, or to enable others of ordinary skill in the art to understand the embodiments disclosed herein.
Claims (8)
1. A flexible physiological signal detection device, characterized in that the device comprises: a flexible substrate, a physiological signal sensor, a force application component and a force application control component,
the flexible substrate is used for bearing the physiological signal sensor and the force application component and is also used for attaching the device to the body surface of a living body;
the physiological signal sensor is positioned on the flexible substrate and close to the surface of the body surface of the organism, is partially embedded into the flexible substrate, and is used for directly contacting with the body surface of the organism and acquiring the physiological signal of the organism;
the force application control component is connected with the physiological signal sensor and the force application component and used for determining a power supply voltage for supplying power to the force application component according to the physiological signal;
the force application component is positioned in the flexible substrate, is positioned above the physiological signal sensor and is not in contact with the physiological signal sensor, and is used for applying pressure to the physiological signal sensor through deformation generated after power supply by the power supply voltage so as to change the contact force between the physiological signal sensor and the body surface of the organism.
2. The apparatus of claim 1, further comprising:
and the adhesive layer is positioned on the surface of the flexible substrate close to the body surface of the organism so as to increase the adhesiveness between the flexible substrate and the body surface of the organism.
3. The device of claim 1, wherein determining a supply voltage to power the force application component from the physiological signal comprises:
determining a current contact force between the physiological signal sensor and the body surface of the living body according to the intensity of the physiological signal;
determining a pressure difference value according to the difference value of the current contact force and the target contact force;
and determining the power supply voltage according to the current power supply voltage of the force application component, the pressure difference value and the corresponding relation between the power supply voltage difference value and the pressure difference value.
4. The device of claim 1, wherein the force application member is disposed in the flexible substrate, the force application member material comprising an electroactive polymer.
5. The device of claim 4, wherein the force applying members are arranged in an array or are of unitary construction.
6. The device of claim 1, wherein a distance between the force applying component and the physiological signal sensor is less than or equal to a distance threshold, or wherein the device has a thickness of 0.5mm-5 mm.
7. The device of claim 1, wherein the physiological signal sensor is positioned at the same level as the surface of the biological body that contacts the surface of the biological body to which the flexible substrate is attached.
8. The apparatus of claim 1, wherein the physiological signal comprises at least one of: body temperature signal, blood pressure signal, heart rate signal.
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