CN111743822A - 一种山苍子油与白藜芦醇组成的防晒组合物 - Google Patents
一种山苍子油与白藜芦醇组成的防晒组合物 Download PDFInfo
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- QNVSXXGDAPORNA-UHFFFAOYSA-N Resveratrol Natural products OC1=CC=CC(C=CC=2C=C(O)C(O)=CC=2)=C1 QNVSXXGDAPORNA-UHFFFAOYSA-N 0.000 title claims abstract description 18
- LUKBXSAWLPMMSZ-OWOJBTEDSA-N Trans-resveratrol Chemical compound C1=CC(O)=CC=C1\C=C\C1=CC(O)=CC(O)=C1 LUKBXSAWLPMMSZ-OWOJBTEDSA-N 0.000 title claims abstract description 18
- 235000021283 resveratrol Nutrition 0.000 title claims abstract description 18
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
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Abstract
本发明属于化妆品领域,提供一种含有山苍子油和白藜芦醇的专门用于防护UVB的防晒组合物,其中山苍子油和白藜芦醇的质量比例为150:1~50:3,优选的质量比例为100:1。
Description
技术领域
本发明属于化妆品领域,涉及一种通过吸收紫外线而达到防晒效果的用途的防晒组合物。
背景技术
太阳紫外线照射人体能消毒杀菌,有益于身体健康,但过量的紫外线会损害人体免疫***,加速肌肤老化,使皮肤变黑、粗糙和松弛,导致各种皮肤病,产生黄褐斑和黑斑,甚至癌变。因此,阳光照射对人体的作用有利有弊。近年来,随着自然界中大气臭氧层出现部分空洞,日光紫外线照射对人体所造成的危害已经越来越受到人们的重视。紫外线分UVB、UVA两种。分别是短波紫外线(UVB:290~320nm)与长波紫外线(UVA:320~400nm)。短波紫外线会令表皮具保护作用的脂质层氧化,使皮肤变干;进一步则使表皮细胞内的核酸和蛋白质变性,产生急性皮炎(即晒伤)等症状,皮肤会变红、发痛。严重时,比如长时间的曝晒,还容易导致皮肤癌变。此外,UVB的长期伤害还会引起黑色素细胞的变异,造成难以消除的太阳斑。长波紫外线UVA穿透力可达真皮,可致皮肤黑化、皱化、老化,甚至出现癌变。随着人们防护意识的不断增强,开发安全、有效的防晒护肤品将成为研究的重要课题。
防晒化妆品的功效性评价(秦钰慧主编,化妆品管理及安全性和功效评价[M],北京:化学工业出版社,2007,,535-536),参见具体操作是:使用紫外分光光度计,在短波紫外线范围内选择8个波长点,分别将加入配方组分的样品溶液置于石英比色皿内,以未加配方组分的溶剂为空白,进行吸光值的测定。吸光度<1.0,表述无防晒效果;吸光度=1.0,表示有低级防晒效果;1.0<吸光度<2.0,表示有中级防晒效果;吸光度>2.0,表示有高级防晒效果。
关于中药的防晒效果,已有文献报道。如:张蕾论述了具有防晒和抗紫外线作用的几种天然植物:黄芩、雪莲和姜黄等的防晒功效,并将其进行萃取、复配后制成植物护肤霜进行防晒效果的测试,证实其具有一定的防晒作用(张蕾.天然植物护肤霜的防晒作用研究[J].日用化学品科学,2008,31(7):21-22)。张木歆等证明茶籽油等在250~360nm处有很好的紫外吸收能力。把天然茶籽油、生物活性物质D按一定比例调配成最佳配方,从240~400nm测定产品紫外吸光度,绘制、分析紫外吸收图谱。将天然茶籽油、生物活性物质(代码)与具有物理防晒的TiO2为紫外吸收剂相结合,制成具有良好的紫外吸收效果的O/w型防晒霜(张木歆,李建平,陈创鑫.茶籽油防晒功效的研究与应用[J].广东化工,2011,38(3):52-54)。
山苍子(Litsea cubaba(lour)Pers.)植物名山鸡椒、木姜子,中药名毕澄茄,为樟科木姜子属的落叶灌木或小乔木。山苍子油,又名山鸡椒油、木姜子油,用水蒸汽蒸馏法从山苍子果实提取的精油。作为调味品的山苍子油系由山苍子精油与食用植物油稀释勾兑而成的一种调味油,有柠檬的香气,具有除膻祛腥、提味增鲜的功效。近年来研究还发现有抗菌,抗氧化等功能(黄光文,卢向阳.我国山苍子油研究概况[J].湖南科技学院学报,2005,26(11):97-100)。李湘洲等于2013年发现了山苍子油的防晒功能(ZL 201310706714.X)。戎伟提出了白藜芦醇的防晒性能(紫外光谱法初步评价46种防晒剂的防晒效果[J].香料香精化妆品,2015(3):53-58.)
发明内容
本发明要解决的技术问题是:提供一种山苍子油和白藜芦醇的防晒组合物,该防晒效果对于UVB波长有良好的吸收紫外线效果。山苍子油与白藜芦醇复配展现出的防晒效果,并非简单叠加效应,产生了意想不到的技术效果。
为解决上述技术问题,本发明所采用的技术方案是:
一种山苍子油与白藜芦醇组成的防晒组合物,所述防晒组合物中山苍子油和白藜芦醇的质量比例为150:1~50:3。
所述山苍子油优选是通过物理压榨法制得的山苍子油。
所述白藜芦醇为市售,含量为98%以上来源于虎杖的化学品。
与现有技术相比,本发明的优势是:
山苍子油与白藜芦醇复配展现出的防晒效果,并非简单叠加效应,产生了意想不到的技术效果,可以制备成一种效果更好的新的防晒化妆品。
具体实施方式
下面结合实施例对本发明做进一步的说明。
1原料:白藜芦醇:所述白藜芦醇可以从市场上直接购得。山苍子油:山苍子通过物理压榨法制得植物油。
2配制方法:见下表1
白藜芦醇溶液:2.5×10-5g/g;:山苍子油溶液:1.25×10-3g/g,溶剂为乙醇。
表1样品配制说明表(体积比例)
3防晒效果的测定:按背景资料方法进行测定,结果见表2-表3:
表2防晒效果对比
吸光度<1.0,表述无防晒效果;吸光度=1.0,表示有低级防晒效果;1.0<吸光度<2.0,表示有中级防晒效果;吸光度>2.0,表示有高级防晒效果。
表2防晒效果对比
Claims (3)
1.一种山苍子油与白藜芦醇组成的防晒组合物,其特征是,所述防晒组合物中山苍子油和白藜芦醇的质量比例为150:1~50:3。
2.根据权利要求1所述防晒组合物,其特征是,其特征是,所述防晒组合物中山苍子油和白藜芦醇的质量比例为100:1。
3.根据权利要求1所述防晒组合物,其特征是,所述山苍子油是通过物理压榨法制得的山苍子油。
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CN113509421A (zh) * | 2021-08-19 | 2021-10-19 | 河南科技大学 | 一种牡丹籽壳化妆品防晒原料及其应用 |
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