CN111656247A - 一种细胞图像处理***、方法、自动读片装置与存储介质 - Google Patents

一种细胞图像处理***、方法、自动读片装置与存储介质 Download PDF

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CN111656247A
CN111656247A CN201880088257.3A CN201880088257A CN111656247A CN 111656247 A CN111656247 A CN 111656247A CN 201880088257 A CN201880088257 A CN 201880088257A CN 111656247 A CN111656247 A CN 111656247A
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cells
cell
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CN111656247B (zh
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叶波
余珊
陈巧妮
邢圆
祁欢
叶燚
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Shenzhen Mindray Bio Medical Electronics Co Ltd
Shenzhen Mindray Scientific Co Ltd
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Shenzhen Mindray Bio Medical Electronics Co Ltd
Shenzhen Mindray Scientific Co Ltd
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    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/365—Control or image processing arrangements for digital or video microscopes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T1/00—General purpose image data processing
    • G06T1/0007—Image acquisition
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T5/00—Image enhancement or restoration
    • G06T5/20—Image enhancement or restoration using local operators
    • G06T5/30—Erosion or dilatation, e.g. thinning
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/50—Depth or shape recovery
    • G06T7/55—Depth or shape recovery from multiple images
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10056—Microscopic image
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30024—Cell structures in vitro; Tissue sections in vitro

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Abstract

本发明公开了一种细胞图像处理***，包括：控制装置，配置为调整数字成像装置与涂片的相对位置；数字成像装置，包括透镜组和数字相机；其中，数字相机配置为相对于涂片的平面发生竖直方向的移动时，拍摄透镜组捕获的视野中细胞的不同对焦深度的图像；显示输出装置，配置为向显示界面输出至少一个视野的不同对焦深度的细胞图像。本发明还公开了一种细胞图像处理***中的细胞图像处理方法、自动读片装置和存储介质。

Description

PCT国内申请，说明书已公开。

Claims (34)

  1. PCT国内申请，权利要求书已公开。
CN201880088257.3A 2018-07-13 2018-07-13 一种细胞图像处理***、方法、自动读片装置与存储介质 Active CN111656247B (zh)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113793336A (zh) * 2021-11-17 2021-12-14 成都西交智汇大数据科技有限公司 一种检测血细胞的方法、装置、设备及可读存储介质
CN114252370A (zh) * 2020-09-25 2022-03-29 深圳迈瑞生物医疗电子股份有限公司 阅片机的细胞重分类方法、样本分析方法及相关设备

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CN114152610B (zh) * 2021-11-02 2023-06-27 桂林优利特医疗电子有限公司 一种基于可视化目标标记的玻片细胞扫描方法

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WO2003102210A2 (en) * 2002-05-30 2003-12-11 The Johns Hopkins University Techniques for automated diagnosis of cell-borne anomalies with a digital optical microscope
JP2004248619A (ja) * 2003-02-21 2004-09-09 Haruo Takabayashi 標的細胞自動探索システム
CN102084399A (zh) * 2008-05-30 2011-06-01 诺维茨公司 通过虚拟分析板进行的试样细胞分析方法
JP2010256077A (ja) * 2009-04-22 2010-11-11 Olympus Corp 細胞画像取得装置及び細胞画像取得方法
TW201104252A (en) * 2009-07-20 2011-02-01 Yaya Tech Co Ltd Cell detecting apparatus
CN103827889A (zh) * 2011-07-19 2014-05-28 奥维茨奥成像***公司 用于检测和/或分类细胞样品中的癌细胞的方法和***
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CN106772975A (zh) * 2017-01-19 2017-05-31 宁波纳美致生物科技有限公司 针对细胞或组织不同深度超分辨率显微成像的照明***
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* Cited by examiner, † Cited by third party
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CN114252370A (zh) * 2020-09-25 2022-03-29 深圳迈瑞生物医疗电子股份有限公司 阅片机的细胞重分类方法、样本分析方法及相关设备
CN113793336A (zh) * 2021-11-17 2021-12-14 成都西交智汇大数据科技有限公司 一种检测血细胞的方法、装置、设备及可读存储介质
CN113793336B (zh) * 2021-11-17 2022-03-11 成都西交智汇大数据科技有限公司 一种检测血细胞的方法、装置、设备及可读存储介质

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