CN111643051A - Reference arm, ophthalmic OCT imaging system and imaging method thereof - Google Patents
Reference arm, ophthalmic OCT imaging system and imaging method thereof Download PDFInfo
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- CN111643051A CN111643051A CN202010527874.8A CN202010527874A CN111643051A CN 111643051 A CN111643051 A CN 111643051A CN 202010527874 A CN202010527874 A CN 202010527874A CN 111643051 A CN111643051 A CN 111643051A
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- 238000003384 imaging method Methods 0.000 title claims abstract description 48
- 230000003287 optical effect Effects 0.000 claims abstract description 104
- 230000007246 mechanism Effects 0.000 claims abstract description 65
- 238000000034 method Methods 0.000 claims description 9
- 239000000919 ceramic Substances 0.000 claims description 3
- 230000002452 interceptive effect Effects 0.000 claims description 3
- 238000012545 processing Methods 0.000 claims description 3
- 238000011084 recovery Methods 0.000 claims description 3
- 238000005452 bending Methods 0.000 abstract description 5
- 238000012634 optical imaging Methods 0.000 abstract description 2
- 230000000007 visual effect Effects 0.000 abstract description 2
- 238000012014 optical coherence tomography Methods 0.000 description 29
- 230000008859 change Effects 0.000 description 9
- 230000008569 process Effects 0.000 description 6
- 238000003745 diagnosis Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 230000003595 spectral effect Effects 0.000 description 2
- 208000017442 Retinal disease Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000001427 coherent effect Effects 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000012631 diagnostic technique Methods 0.000 description 1
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 208000030533 eye disease Diseases 0.000 description 1
- 230000004402 high myopia Effects 0.000 description 1
- 239000013307 optical fiber Substances 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/102—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for optical coherence tomography [OCT]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/12—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes
- A61B3/1225—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes using coherent radiation
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
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Abstract
The invention discloses a reference arm, an ophthalmic OCT imaging system and an imaging method thereof, and belongs to the technical field of optical imaging. The reference arm comprises an optical path adjusting mechanism and a reflector capable of reflecting incident light in a primary path; the optical path adjusting mechanism comprises an optical path coarse adjusting mechanism and an optical path fine adjusting mechanism arranged on the optical path coarse adjusting mechanism; the reflector is arranged on the optical path fine adjustment mechanism. When the reference arm and the ophthalmic OCT imaging system are used for scanning the fundus of the eye to be inspected, the optical path of the reference arm can be conveniently and quickly adjusted, so that the imaging depth is increased, the signal-to-noise ratio is improved, the image bending degree is reduced, and a larger imaging visual field range is obtained.
Description
Technical Field
The invention relates to a reference arm, an ophthalmic OCT imaging system and an imaging method thereof, belonging to the technical field of optical imaging.
Background
Optical Coherence Tomography (OCT) is a new optical diagnostic technique that has rapidly developed in recent years. The ophthalmic OCT imaging system is one of the most commonly used examination methods for fundus diseases, and has great clinical significance in the aspects of screening, diagnosis, follow-up observation, treatment effect evaluation and the like of eye diseases, particularly fundus retinal diseases. The reference arm is a very important component, and provides a reference light path, so that a determined aplanatism is generated between the sample arm and the reference arm, and a clear interference image is formed.
At present, based on the imaging principle of OCT imaging, interference imaging can be performed only if the optical path difference between a sample arm and a reference arm is within the coherence length, so that imaging cannot be performed when the optical path difference of the sample arm at different positions in scanning exceeds the interference length. In the conventional spectral domain OCT, the position of the reference arm is kept unchanged when fundus scanning is carried out, so that images can be bent to different degrees along with the change of the optical path of the sample arm in the scanning process, and the bending degree is related to the change of the optical path of the sample arm.
Chinese patent No. cn201520546371.x, 12/30/2015, discloses an OCT reference arm structure and an OCT imaging system, wherein the OCT reference arm and an OCT sample arm are connected in parallel to two different ports of an optical fiber coupler, and the OCT reference arm and the OCT sample arm include a collimating coupling mirror, a laser energy adjusting unit, and at least one right-angle prism capable of performing dispersion compensation and folding an optical path, which are sequentially arranged in the output direction of the ports, and a corner cube capable of reflecting incident light in the original path is further arranged in the reflection direction of the right-angle prism. The back scattering mirror of the pyramid prism moves back and forth along with the linear motor, but the reference arm is kept fixed in the whole fundus scanning process, the OCT image is bent along with the change of the optical path of the sample arm, the quality of the part of the image which is bent greatly is reduced, and the imaging depth is limited.
Disclosure of Invention
The invention aims to overcome the defects in the prior art, provides a reference arm, an ophthalmic OCT imaging system and an imaging method thereof, and solves the technical problems that in the prior art, during fundus scanning, the reference arm is fixed and cannot be adjusted according to the change of the optical path of a sample arm, so that OCT images are bent, and the image quality is reduced.
In order to solve the technical problems, the invention is realized by adopting the following technical scheme:
in a first aspect, the present invention provides a reference arm, comprising an optical path adjusting mechanism and a mirror capable of reflecting incident light in a primary path; the optical path adjusting mechanism comprises an optical path coarse adjusting mechanism and an optical path fine adjusting mechanism arranged on the optical path coarse adjusting mechanism; the reflector is arranged on the optical path fine adjustment mechanism.
Furthermore, the optical path coarse adjustment mechanism comprises a linear guide rail and a driving mechanism, the linear guide rail is laid along the incident or reflection direction of light, and the optical path fine adjustment mechanism and the reflector can move along the linear guide rail under the driving of the driving mechanism.
Further, the optical path coarse adjustment mechanism is a linear motor, and the linear motor can drive the optical path fine adjustment mechanism and the reflector to move along the light incidence or reflection direction.
Further, the optical path fine adjustment mechanism is a piezoelectric ceramic motor, or a voice coil motor, or a galvanometer.
Further, the reflector is any one of a right-angle prism and a plane reflector.
In a second aspect, the present invention provides an ophthalmic OCT imaging system comprising a coupler, a sample arm, and a reference arm of any one of the preceding claims; the reference arm and the sample arm are connected to two different ports of the coupler, respectively.
In a third aspect, the present invention provides an imaging method of an ophthalmic OCT imaging system, the method comprising:
step A: roughly adjusting the optical path of the reference arm by using an optical path rough adjusting mechanism to enable optical signals reflected by the reference arm to enter the coupler, and interfering the optical signals reflected by the same arm to generate an eyeground interference image;
and B: when the sample arm carries out image scanning, the optical path of the reference arm is compensated and adjusted by using an optical path fine adjustment mechanism so as to obtain a flat fundus interference image;
and C: and performing image recovery processing according to the optical path of the reference arm and the acquired flat fundus interference image to acquire a real fundus OCT image.
Furthermore, the imaging method also comprises the step of expanding the image scanning range of the sample arm after the optical path of the reference arm is compensated and adjusted.
Compared with the prior art, the invention has the following beneficial effects:
according to the change of the optical path of the sample arm, the optical path adjusting mechanism in the reference arm is adjusted, so that the reference arm can be respectively positioned at the equal optical path position when the scanning is started and in the scanning process, the adjustment of the optical path of the reference arm is realized, the bending degree of an interference image is reduced, and the imaging depth is increased.
Drawings
Fig. 1 is a schematic diagram of an optical path adjusting mechanism of a reference arm according to an embodiment of the present invention;
FIG. 2 is a schematic diagram of an ophthalmic OCT imaging system provided in accordance with an embodiment of the invention;
FIG. 3 is a flow chart of an imaging method of the ophthalmic OCT imaging system of FIG. 2;
in the figure: 10. an optical path coarse adjustment mechanism; 20. an optical path fine-tuning mechanism; 30. a mirror; 11. a drive mechanism; 12. a linear guide rail.
Detailed Description
The invention is further described below with reference to the accompanying drawings. The following examples are only for illustrating the technical solutions of the present invention more clearly, and the protection scope of the present invention is not limited thereby.
In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on those shown in the drawings, and are used only for convenience in describing the present invention and for simplicity in description, and do not indicate or imply that the referenced devices or elements must have a particular orientation, be constructed and operated in a particular orientation, and thus, are not to be construed as limiting the present invention.
In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood by those of ordinary skill in the art through specific situations.
As shown in fig. 1, the embodiment of the present invention provides a reference arm, which includes an optical path adjusting mechanism and a mirror 30 capable of reflecting incident light in a primary path; the optical path adjusting mechanism comprises an optical path coarse adjusting mechanism 10 and an optical path fine adjusting mechanism 20 arranged on the optical path coarse adjusting mechanism 10, wherein the optical path fine adjusting mechanism 20 is any one of piezoelectric ceramic motors, voice coil motors, vibrating mirrors and other mechanisms with fine adjusting functions; the reflecting mirror 30 is connected to the optical path fine adjustment mechanism 20, and the reflecting mirror 30 may be a rectangular prism, a plane mirror, or the like. The optical path coarse adjustment mechanism 10 includes a linear guide rail 12 and a driving mechanism 11, the linear guide rail 12 is laid along the light incidence or reflection direction, the optical path fine adjustment mechanism 20 and the reflecting mirror 30 can move along the linear guide rail 12 under the driving of the driving mechanism 11, thereby realizing the coarse adjustment of the optical path of the reference arm, and then the optical path fine adjustment mechanism 20 is adjusted to adjust the position of the reflecting mirror 30, thereby realizing the rapid fine adjustment of the optical path of the reference arm.
In an embodiment of the present invention, the optical path coarse adjustment mechanism 10 may also be a linear motor or other linear moving mechanism, and the linear motor can drive the optical path fine adjustment mechanism 20 and the reflection mirror 30 to move along the incident or reflection direction of the light.
In performing a fundus scan, the sample arm may perform a B-scan (transverse scan) or an A-scan (longitudinal scan) of the fundus. When the sample arm starts fundus scanning, the reference arm is adjusted, the optical path fine adjustment mechanism 20 and the reflector 30 on the driving mechanism 11 can be moved in the direction of incident light by adjusting the driving mechanism 11, the reflection position of the incident light of the reference arm is roughly adjusted, the reflection position of the incident light of the reference arm is positioned at a reference position, even if the reflected light of the reference arm and the sample arm keeps equal optical path or approximate equal optical path, so that the optical path difference of the light of the reference arm and the light of the sample arm is within a coherent length and generates interference, a clear interference image is obtained, and the optical path rough adjustment mechanism 10 can roughly adjust the optical path range of the reflected light of the reference arm within a large range to complete the preparation positioning work of scanning the fundus; in the sample arm scanning process, according to the change of the optical path of the reflected light of different parts of the fundus scanned by the sample arm, the optical path fine adjustment mechanism 20 can be quickly adjusted in a small range in real time, so that the position of the reflecting mirror 30 on the optical path fine adjustment mechanism 20 is changed, the reflection position of the incident light of the reference arm is positioned at an aplanatism position or an approximate aplanatism position, namely the optical path of the reference arm and the optical path of the sample arm are kept synchronous and interference can be realized. It should be noted that the aplanatic positions of the reference arm and the sample arm change with the change of the optical path of the sample arm.
The reference arm can respectively adjust the optical path of the reference arm at the beginning and in the scanning process of scanning, so that the optical path of the reference arm and the optical path of the sample arm are kept or approximate to equal optical path, the optical path compensation of the reference arm is increased, and the signal-to-noise ratio of optical signals is improved, thereby reducing the bending degree of fundus imaging images, increasing the imaging depth and improving the fundus imaging image quality.
As shown in fig. 2, an ophthalmic OCT imaging system according to an embodiment of the present invention includes an OCT imaging light source, a coupler, a spectrometer, a sample arm, and the reference arm, where the reference arm and the sample arm are respectively connected to two different ports of the coupler. Light emitted by the OCT imaging light source enters the sample arm and the reference arm respectively after being split by the coupler, enters the coupler respectively after being reflected by the sample arm and the reference arm, is combined into a beam of light to generate interference, and is output from the other port of the coupler and then is received by a spectrometer connected to the coupler.
As shown in fig. 3, an embodiment of the present invention provides an imaging method of an ophthalmic OCT imaging system, which includes the following specific steps:
step A: roughly adjusting the optical path of the reference arm by using an optical path rough adjusting mechanism 10, keeping the light reflected by the reference arm and the sample arm in an equal optical path or an approximate equal optical path, enabling the optical signal reflected by the reference arm to enter a coupler, and interfering the optical signal reflected by the sample arm to generate a fundus interference image;
and B: while the sample arm scans images, the optical path of the reference arm is compensated and adjusted by using an optical path fine adjustment mechanism 20, so that the reflected light of the reference arm and the sample arm keeps an aplanatism or an approximate aplanatism, and a flat fundus interference image is obtained;
and C: and performing image recovery processing according to the optical path of the reference arm and the acquired flat fundus interference image to acquire a real fundus OCT image.
Based on the imaging property of the spectral domain OCT spectrometer, when the sample arm is at different positions and the optical path difference between the sample arm and the reference arm exceeds the interference length or is far away from the aplanatism, the image quality is lower than that of the reference arm and the sample arm at the aplanatism position due to the reduction of the signal-to-noise ratio, and therefore the image quality of the periphery of the eyeground is reduced when the eye is highly myopic. The imaging method of the ophthalmic OCT imaging system provided by the embodiment can be used for examination and diagnosis of high-myopia eyes, and the influence of the interference length of the traditional OCT is avoided by performing light supplement adjustment on the optical path of the reference arm, namely the transverse field of view of the interference image is limited by the change of the imaging depth of the eyeground, so that the problem of the reduction of the image quality of the periphery of the eyeground is solved, and a larger imaging field range can be obtained.
In the fundus examination scanning process, the operations from the step a to the step C in the imaging method can be repeated for a plurality of times according to specific conditions, and the fundus interference image with small bending degree, large imaging depth and large imaging visual field range can be obtained by coarsely and finely adjusting the optical path of the reference arm.
The above description is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, several modifications and variations can be made without departing from the technical principle of the present invention, and these modifications and variations should also be regarded as the protection scope of the present invention.
Claims (8)
1. A reference arm is characterized by comprising an optical path adjusting mechanism and a reflector capable of reflecting incident light in a primary path;
the optical path adjusting mechanism comprises an optical path coarse adjusting mechanism and an optical path fine adjusting mechanism arranged on the optical path coarse adjusting mechanism; the reflector is arranged on the optical path fine adjustment mechanism.
2. The reference arm according to claim 1, characterized in that the optical path coarse adjustment mechanism comprises a linear guide rail and a driving mechanism, the linear guide rail is laid along the light incidence or reflection direction, and the optical path fine adjustment mechanism and the reflecting mirror can move along the linear guide rail under the driving of the driving mechanism.
3. The reference arm of claim 1, wherein the optical path coarse adjustment mechanism is a linear motor, and the linear motor can drive the optical path fine adjustment mechanism and the reflector to move along the incident or reflecting direction of the light.
4. The reference arm according to claim 1, wherein the optical path fine tuning mechanism is a piezo ceramic motor, or a voice coil motor, or a galvanometer.
5. The reference arm of claim 1, wherein the mirror is any one of a right angle prism, a flat mirror.
6. An ophthalmic OCT imaging system comprising a coupler, a sample arm, and the reference arm of any one of claims 1 to 5; the reference arm and the sample arm are connected to two different ports of the coupler, respectively.
7. An imaging method of an ophthalmic OCT imaging system of claim 6, the method comprising:
step A: roughly adjusting the optical path of the reference arm by using an optical path rough adjusting mechanism to enable optical signals reflected by the reference arm to enter the coupler, and interfering the optical signals reflected by the same arm to generate an eyeground interference image;
and B: when the sample arm carries out image scanning, the optical path of the reference arm is compensated and adjusted by using an optical path fine adjustment mechanism so as to obtain a flat fundus interference image;
and C: and performing image recovery processing according to the optical path of the reference arm and the acquired flat fundus interference image to acquire a real fundus OCT image.
8. The imaging method of claim 7, further comprising expanding an image scan range of the sample arm after compensating for adjustments to the reference arm optical path length.
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| Application Number | Priority Date | Filing Date | Title |
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| CN202010527874.8A CN111643051A (en) | 2020-06-11 | 2020-06-11 | Reference arm, ophthalmic OCT imaging system and imaging method thereof |
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| CN202010527874.8A CN111643051A (en) | 2020-06-11 | 2020-06-11 | Reference arm, ophthalmic OCT imaging system and imaging method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117146700A (en) * | 2023-10-30 | 2023-12-01 | 天津恒宇医疗科技有限公司 | OCT equipment optical path calibration method and device and OCT equipment |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2296531A1 (en) * | 2008-04-23 | 2011-03-23 | Bioptigen, Inc. | Optical coherence tomography (oct) imaging systems for use in pediatric ophthalmic applications and related methods and computer program products |
| CN206333889U (en) * | 2016-07-28 | 2017-07-18 | 南方科技大学 | A kind of OCT reference arms self-checking device |
| CN108433697A (en) * | 2018-04-26 | 2018-08-24 | 天津市索维电子技术有限公司 | It is a kind of to realize the device assessed in ophthalmologic operation art |
| CN110013212A (en) * | 2019-04-23 | 2019-07-16 | 广东唯仁医疗科技有限公司 | Multi-parameter, multi-functional eyes measuring instrument based on optical coherence tomography |
-
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- 2020-06-11 CN CN202010527874.8A patent/CN111643051A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2296531A1 (en) * | 2008-04-23 | 2011-03-23 | Bioptigen, Inc. | Optical coherence tomography (oct) imaging systems for use in pediatric ophthalmic applications and related methods and computer program products |
| CN206333889U (en) * | 2016-07-28 | 2017-07-18 | 南方科技大学 | A kind of OCT reference arms self-checking device |
| CN108433697A (en) * | 2018-04-26 | 2018-08-24 | 天津市索维电子技术有限公司 | It is a kind of to realize the device assessed in ophthalmologic operation art |
| CN110013212A (en) * | 2019-04-23 | 2019-07-16 | 广东唯仁医疗科技有限公司 | Multi-parameter, multi-functional eyes measuring instrument based on optical coherence tomography |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117146700A (en) * | 2023-10-30 | 2023-12-01 | 天津恒宇医疗科技有限公司 | OCT equipment optical path calibration method and device and OCT equipment |
| CN117146700B (en) * | 2023-10-30 | 2024-01-30 | 天津恒宇医疗科技有限公司 | OCT equipment optical path calibration method and device and OCT equipment |
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Application publication date: 20200911 |